Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
IGF2R 3482 CHEMBL402001 CHEMBL402001 DrugBank 17139284, 17016423, 10592235

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
IGF2R rs8191725 AG salbutamol efficacy yes The allele associated with increased response and low frequency is not explicitly stated. Response is increased for carriers of the rare, minor allele. This association was significant in the initial GWAS (in GALA II), but it was not significant in an attempted replication by imputation in silico in GALA I. GALAII genotyping was done using the Affymetrix LAT1 Array, which was designed to capture Latino population variation. Genotype AG is associated with increased response to salbutamol in children with Asthma as compared to genotype AA. 23992748 1183680038