PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RHOA	0	CAV1	0	pull down	Nethe M (2010)	1
ARHGDIA	3	MSN	0	biochemical, biochemical	Gajate C (2005), Wan C (2015)	2
CASP8AP2	3	FADD	1	affinity chromatography technology	Imai Y (1999)	1
BABAM2	2	FAS	2	affinity chromatography technology, affinity chromatography technology	Li Q (2004), Li Q (2004)	2
PML	7	DAXX	5	two hybrid, two hybrid, affinity chromatography technology, imaging technique, two hybrid, affinity chromatography technology, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique	Ishov AM (1999), Li H (2000), Li H (2000), Li H (2000), Lehembre F (2001), Zhong S (2000), Cuchet-Lourenco D (2011), Chu Y (2011), Meinecke I (2007), Jang MS (2002), Chang CC (2011), Wethkamp N (2011), Ferguson BJ (2007), Delbarre E (2013), Delbarre E (2013), Sahin U (2014), Lin DY (2006), Lin DY (2006), Lin DY (2006), Lin DY (2006), Torii S (1999)	21
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
FASLG	0	PIK3R1	6	imaging technique	Chen TC (2014)	1
CTNNB1	30	EZR	8	affinity chromatography technology	Hiscox S (1999)	1
FAS	2	TCAP	0	two hybrid	Wang J (2011)	1
EZR	8	TNFRSF1A	3	biochemical	Gajate C (2005)	1
BID	1	FASLG	0	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
ECSIT	3	ACAD9	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Guarani V (2014), Guarani V (2014), Nouws J (2010), Nouws J (2010), Huttlin EL (2017)	6
CFLAR	1	TNFRSF1A	3	genetic interference	Ma Y (2017)	1
CASP10	1	RIPK1	2	affinity chromatography technology	Chaudhary PM (2000)	1
FAS	2	NDUFAF1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNFRSF1A	3	TRAF3	1	pull down	Mosialos G (1995)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
BID	1	TNFRSF1A	3	biochemical	Gajate C (2005)	1
CASP8	1	RIPK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chaudhary PM (2000), Oshima S (2009), Bertrand MJ (2008), Knox PG (2011), Kim S (2010), Cheung HH (2009), Tenev T (2011), Tenev T (2011), Mahul-Mellier AL (2011), Legarda-Addison D (2009), Biton S (2011), Bellail AC (2012), Bellail AC (2012), Lee EW (2012), Rebe C (2007), Feoktistova M (2012), Puliyappadamba VT (2013), Wu P (2014), Wu P (2014), Feoktistova M (2011), Selmi T (2015), Yamaguchi N (2015), Moquin DM (2013), Ranjan K (2016), Zinngrebe J (2016), Nakazawa S (2016), Zheng M (2016)	27
FAS	2	MAPK8	3	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
HNRNPC	0	UBE2I	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RHOA	0	BID	1	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
EHD1	5	FADD	1	biochemical	Wan C (2015)	1
CASP8	1	RB1	2	enzymatic study	Lemaire C (2005)	1
PML	7	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down	Alcalay M (1998), Alcalay M (1998), Alcalay M (1998)	3
FAS	2	PEX1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CASP10	1	TNFRSF10B	1	biochemical, affinity chromatography technology	Gajate C (2005), MacFarlane M (1997)	2
LCK	0	FAS	2	pull down	Schlottmann KE (1996)	1
TUBB3	3	MSN	0	biochemical	Kristensen AR (2012)	1
FAF1	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang L (2011), Zhang L (2012), Kim H (2015)	3
ARHGDIA	3	TNFRSF10B	1	biochemical	Gajate C (2005)	1
DAXX	5	SUMO1	0	two hybrid, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, two hybrid, x-ray crystallography, two hybrid	Lin DY (2002), Ryu SW (2000), Ryu SW (2000), Ryu SW (2000), Escobar-Cabrera E (2011), Escobar-Cabrera E (2011), Naik MT (2011), Chang CC (2011), Chang CC (2011), Chen A (2006), Chen A (2006), Saul VV (2014), Ullmann R (2012), Lin DY (2006), Lin DY (2006), Ullmann R (2012), Ullmann R (2012), Lin DY (2006), Naik MT (2011), Li C (2017)	20
BID	1	CRMP1	0	two hybrid	Vinayagam A (2011)	1
MSN	0	BID	1	biochemical	Gajate C (2005)	1
CASP10	1	FASLG	0	biochemical	Gajate C (2005)	1
TMX1	4	SQSTM1	0	affinity chromatography technology	Huttlin EL (2017)	1
FAS	2	FADD	1	biochemical, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Gajate C (2005), MacFarlane M (1997), Pan G (1997), Huang B (1996), Huang B (1996), Chinnaiyan AM (1995), Chinnaiyan AM (1995), Chinnaiyan AM (1995), Thomas LR (2002), Kumar A (2001), Lee EW (2012), Zhang M (2011), Huttlin EL (2015), Chen TC (2014), Jeong M (2017), Huttlin EL (2017), Kleber S (2008), Torii S (1999), Torii S (1999), Chang HY (1999)	20
GADD45A	1	RARA	5	affinity chromatography technology	Yi YW (2000)	1
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
SQSTM1	0	FAS	2	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Liang X (2013)	2
FAS	2	TRAF3	1	pull down	Mosialos G (1995)	1
CASP8	1	FADD	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Micheau O (2003), Srinivasula SM (1997), Srinivasula SM (1997), Henshall DC (2003), Boldin MP (1996), Oshima S (2009), Thomas LR (2002), Ikner A (2011), Tenev T (2011), Ramakrishnan P (2011), Mahul-Mellier AL (2011), Won M (2010), Ryu SW (2003), Sinha SK (2004), Biton S (2011), Fu K (2012), Fu K (2012), Gonzalvez F (2012), Lee EW (2012), Rebe C (2007), Feoktistova M (2012), Wang J (2011), Puliyappadamba VT (2013), Choi H (2011), Feoktistova M (2011), Selmi T (2015), Yamaguchi N (2015), Saitoh Y (2016), Moquin DM (2013), Ranjan K (2016), Nakazawa S (2016), Jeong M (2017), Jeong M (2017), Pescatore A (2016)	35
TP63	0	DAXX	5	two hybrid, affinity chromatography technology, two hybrid, pull down	Kim EJ (2003), Kim EJ (2003), Gostissa M (2004), Gostissa M (2004)	4
RHOA	0	CRMP1	0	genetic interference	Leung T (2002)	1
FAS	2	ARHGDIA	3	biochemical	Gajate C (2005)	1
FAS	2	DAXX	5	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down	Ko YG (2001), Kim YY (2003), Cermak L (2002), Yang X (1997), Yang X (1997), Yang X (1997), Charette SJ (2000), Chen TC (2014), Chang HY (1999)	9
FASLG	0	FYN	1	pull down, pull down, pull down, unspecified method, imaging technique	Wenzel J (2001), Hane M (1995), Zuccato E (2007), Voss M (2009), Chen TC (2014)	5
FAS	2	METTL13	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
C17orf75	1	FAM91A1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	MDN1	19	affinity chromatography technology	Huttlin EL (2015)	1
FAS	2	FAS	2	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Stanger BZ (1995), Wright DA (1996), Zhang M (2011), Kleber S (2008)	4
SQSTM1	0	RIPK1	2	pull down, affinity chromatography technology, affinity chromatography technology	Sanz L (1999), Sanz L (1999), Sanz L (1999)	3
FAS	2	ALDH16A1	4	affinity chromatography technology	Huttlin EL (2015)	1
TNFRSF1A	3	SUMO1	0	two hybrid, two hybrid, pull down	Liou ML (1999), Okura T (1996), Okura T (1996)	3
FAS	2	DPH1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
YES1	1	FYN	1	affinity chromatography technology, affinity chromatography technology	Piedra J (2003), Huttlin EL (2017)	2
FAS	2	RHOBTB3	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	MAP1S	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TUBB2B	2	TUBB3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNFRSF1A	3	DPH1	7	affinity chromatography technology	Huttlin EL (2017)	1
TP63	0	EEF1A1	0	affinity chromatography technology	Amoresano A (2010)	1
FYN	1	TCAP	0	two hybrid	Wang J (2011)	1
DAXX	5	TRAF3	1	two hybrid	Wang J (2011)	1
EHD1	5	NOL3	0	biochemical	Kristensen AR (2012)	1
EZR	8	CASP8	1	biochemical	Gajate C (2005)	1
UBE2I	0	RB1	2	enzymatic study, pull down	Ledl A (2005), Ledl A (2005)	2
FAS	2	YES1	1	affinity chromatography technology	Kleber S (2008)	1
BID	1	TNFRSF10B	1	biochemical	Gajate C (2005)	1
RIPK1	2	FADD	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen D (2002), Young JA (2011), Tenev T (2011), Ramakrishnan P (2011), Legarda-Addison D (2009), ODonnell MA (2012), Vanlangenakker N (2011), Biton S (2011), Biton S (2011), Lee EW (2012), Puliyappadamba VT (2013), Wu P (2014), Huttlin EL (2015), Baratchian M (2016), Moquin DM (2013), Ranjan K (2016), Pescatore A (2016), Zheng M (2016)	18
CASP8	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pan JA (2011), Huang S (2013), Huang S (2013)	3
FAS	2	TUBB4A	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Kleber S (2008), Kleber S (2008)	2
HIPK3	5	FAS	2	affinity chromatography technology	Rochat-Steiner V (2000)	1
RHOA	0	FADD	1	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
ARHGDIA	3	EZR	8	biochemical, biochemical	Gajate C (2005), Wan C (2015)	2
FAS	2	CTNNB1	30	imaging technique	Chen TC (2014)	1
UBE2I	0	TNFRSF1A	3	two hybrid, pull down	Saltzman A (1998), Saltzman A (1998)	2
EZR	8	PRKCA	7	affinity chromatography technology	Ng T (2001)	1
MAPK8	3	CASP10	1	biochemical	Gajate C (2005)	1
MAPK8	3	FASLG	0	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
RARA	5	UBQLN1	1	two hybrid, pull down	Zhu D (2010), Zhu D (2010)	2
MSN	0	FASLG	0	biochemical	Gajate C (2005)	1
CASP8	1	FAF1	1	affinity chromatography technology, affinity chromatography technology	Knox PG (2011), Caballero-Lopez MJ (2017)	2
TRAF3	1	CFLAR	1	affinity chromatography technology	Kataoka T (2000)	1
FAS	2	PRKCA	7	imaging technique	Chen TC (2014)	1
PML	7	SQSTM1	0	affinity chromatography technology	Hein MY (2015)	1
RARA	5	FAS	2	affinity chromatography technology	Tao RH (2011)	1
TNF	0	TRADD	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Micheau O (2003), Legler DF (2003), Kuai J (2004), Kuai J (2004), Haas TL (2009), Ea CK (2006), Skaug B (2011), Fu J (2013), Fritsch J (2014), Schlicher L (2016)	10
FAS	2	CHD1L	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAF2	4	NDUFAF1	0	affinity chromatography technology	Huttlin EL (2015)	1
TNFRSF1A	3	TNFRSF10B	1	biochemical	Gajate C (2005)	1
FAS	2	TMX1	4	two hybrid	Wang J (2011)	1
FAS	2	TIMM29	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CASP8	1	TNFRSF1A	3	biochemical	Gajate C (2005)	1
FAS	2	UFSP2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PML	7	TP63	0	affinity chromatography technology, pull down	Bernassola F (2005), Bernassola F (2005)	2
RAP1A	1	FADD	1	pull down	Stoletov KV (2004)	1
ARHGDIA	3	RHOA	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, biochemical, pull down, biochemical, pull down, x-ray crystallography	Ewing RM (2007), Gajate C (2005), Michaelson D (2001), Gorvel JP (1998), Faure J (2001), Man JH (2010), Rolland T (2014), Wan C (2015), Jaffe AB (2004), Kuhlmann N (2016), Kuhlmann N (2016), Kuhlmann N (2016)	12
CFLAR	1	NOL3	0	genetic interference	Koseki T (1998)	1
TNF	0	CASP8	1	affinity chromatography technology	Fritsch J (2014)	1
CASP10	1	CASP8	1	biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Micheau O (2003), Micheau O (2003), Guo Y (2002), Srinivasula SM (1996), Srinivasula SM (1996), Sinha SK (2004), Lee EW (2012), Feoktistova M (2011)	9
SUMO1	0	FAM118B	0	two hybrid	Rolland T (2014)	1
FAS	2	TUBB2A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SUMO1	0	FBF1	2	two hybrid	Rolland T (2014)	1
FAS	2	WRB	0	affinity chromatography technology	Huttlin EL (2015)	1
FAS	2	UBQLN1	1	two hybrid	Wang J (2011)	1
FAS	2	GPN3	4	affinity chromatography technology	Huttlin EL (2017)	1
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
LCK	0	SQSTM1	0	pull down	Joung I (1996)	1
RB1	2	MAPK8	3	affinity chromatography technology	Li H (2001)	1
HIPK3	5	SUMO1	0	two hybrid	Minty A (2000)	1
PIK3R1	6	MAP3K5	1	affinity chromatography technology, affinity chromatography technology	Xie D (2009), Xie D (2009)	2
FASLG	0	SRC	2	unspecified method	Voss M (2009)	1
FAF2	4	ARF5	0	affinity chromatography technology	Christianson JC (2012)	1
BID	1	CASP10	1	biochemical	Gajate C (2005)	1
MAPK8	3	CASP8	1	biochemical	Gajate C (2005)	1
TNF	0	FAS	2	affinity chromatography technology	Legler DF (2003)	1
SQSTM1	0	PIK3R1	6	far western blotting, affinity chromatography technology	Sung CK (1998), Sung CK (1998)	2
FAS	2	CRMP1	0	two hybrid	Stelzl U (2005)	1
TNFRSF1A	3	TNF	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Bouwmeester T (2004), Micheau O (2003), Legler DF (2003), Kuai J (2004), Skaug B (2011), Tokunaga F (2012), Klingseisen L (2012), Thoma B (1990), Keusekotten K (2013), Crowe PD (1994), Liu LS (1998), Higuchi M (1992), Chaturvedi MM (1994), Schaeffer V (2014), Fritsch J (2014), Chainy GB (1996), Huttlin EL (2015), Chen TC (2014), Yamaguchi N (2015), Draber P (2015), Pescatore A (2016), Huttlin EL (2017), Nielsen FS (2004), Ameloot P (2001)	24
FASLG	0	CFLAR	1	affinity chromatography technology	Tao RH (2011)	1
BID	1	CASP8	1	biochemical, enzymatic study	Gajate C (2005), Guo Y (2002)	2
EZR	8	CASP10	1	biochemical	Gajate C (2005)	1
RHOA	0	CASP8	1	biochemical	Gajate C (2005)	1
EZR	8	MAPK8	3	biochemical	Gajate C (2005)	1
SQSTM1	0	BID	1	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Liang X (2013)	2
FAS	2	CASP10	1	biochemical, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Vincenz C (1997), MacFarlane M (1997)	3
CASP8AP2	3	SUMO1	0	affinity chromatography technology	Sun H (2012)	1
FAF2	4	CAV1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNF	0	FADD	1	affinity chromatography technology	Fritsch J (2014)	1
FAS	2	SRC	2	affinity chromatography technology	Kleber S (2008)	1
CCND3	1	RARA	5	two hybrid, pull down, affinity chromatography technology	Despouy G (2003), Despouy G (2003), Despouy G (2003)	3
CASP8	1	FASLG	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Micheau O (2003), Legler DF (2003), Tao RH (2011)	4
PDCD6	2	MAP3K5	1	affinity chromatography technology, pull down, imaging technique	Hwang IS (2002), Hwang IS (2002), Hwang IS (2002)	3
RHOA	0	MAPK8	3	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
SRC	2	CRMP1	0	two hybrid	Vinayagam A (2011)	1
CTNNB1	30	MAPK8	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lee MH (2009), Lee MH (2009), Lee MH (2009)	3
BAG6	2	LCK	0	affinity chromatography technology, affinity chromatography technology	Rangachari M (2012), Rangachari M (2012)	2
TNFSF13	0	TNFRSF1A	3	pull down	Kelly K (2000)	1
C17orf75	1	WDR11	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	UBE2I	0	affinity chromatography technology, two hybrid, pull down, two hybrid	Becker K (1997), Wright DA (1996), Wright DA (1996), Wright DA (1996)	4
PML	7	SUMO1	0	two hybrid, imaging technique, fluorescent resonance energy transfe, two hybrid, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, x-ray crystallography, fluorescent resonance energy transfe, unspecified method, two hybrid, pull down	Lin DY (2002), Cuchet-Lourenco D (2011), Percherancier Y (2009), Cuchet-Lourenco D (2012), Stehmeier P (2009), Duprez E (1999), Shen TH (2006), Shen TH (2006), Saether T (2007), Cappadocia L (2015), Cappadocia L (2015), Cappadocia L (2015), Li C (2017), Li C (2017)	14
RHOA	0	CASP10	1	biochemical	Gajate C (2005)	1
PML	7	FAS	2	affinity chromatography technology	Tao RH (2011)	1
FAS	2	EZR	8	biochemical	Gajate C (2005)	1
MAP3K5	1	DAXX	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Chang HY (1998), Chang HY (1998), Fukuyo Y (2009), Ko YG (2001), Ko YG (2001), Junn E (2005), Song JJ (2004), Charette SJ (2000), Chen TC (2014), Donath S (2016)	10
FAS	2	FAF2	4	two hybrid	Imai Y (2002)	1
ARHGDIA	3	MAPK8	3	biochemical	Gajate C (2005)	1
FAS	2	MAP3K5	1	affinity chromatography technology, imaging technique	Ko YG (2001), Chen TC (2014)	2
TNFRSF1A	3	TRADD	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang Y (1999), Schuetze S (1999), Pan G (1997), Hsu H (1996), Hsu H (1996), Hsu H (1996), Shu HB (1996), Blankenship JW (2009), Kolliputi N (2009), Fujikura D (2012), Park KJ (2002), Guan YJ (2011), Hsu H (1995), Kumar A (2001), Zheng L (2006), Kim TW (2013), Zhang H (2004), Chang YL (2014), Nakazawa S (2016), Huttlin EL (2017)	20
KRIT1	1	FAS	2	affinity chromatography technology, pull down	Ahn EY (2004), Ahn EY (2004)	2
MSN	0	FADD	1	biochemical	Gajate C (2005)	1
FAF2	4	ECSIT	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNFSF13	0	FAS	2	pull down	Kelly K (2000)	1
CASP10	1	CASP8AP2	3	two hybrid	McDonald ER (2004)	1
FAS	2	TRADD	0	affinity chromatography technology	Kumar A (2001)	1
PML	7	CTNNB1	30	affinity chromatography technology, pull down, affinity chromatography technology	Satow R (2012), Satow R (2012), Shtutman M (2002)	3
CASP8	1	TRADD	0	affinity chromatography technology, affinity chromatography technology	Micheau O (2003), Kolliputi N (2009)	2
FAS	2	CTU2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNF	0	RIPK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legler DF (2003), Haas TL (2009), Ea CK (2006), Ramakrishnan P (2011), Skaug B (2011), Darding M (2011), Tokunaga F (2012), Klingseisen L (2012), Schaeffer V (2014), Fritsch J (2014), Yamaguchi N (2015), Draber P (2015), Pescatore A (2016), Schlicher L (2016)	14
FAF2	4	TUBB3	3	affinity chromatography technology	Raman M (2015)	1
GADD45A	1	EEF1A1	0	two hybrid	Vinayagam A (2011)	1
MSN	0	CASP8	1	biochemical	Gajate C (2005)	1
RB1	2	BAG6	2	affinity chromatography technology	Hein MY (2015)	1
CFLAR	1	RIPK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kataoka T (2000), Chaudhary PM (2000), Rebe C (2007), Feoktistova M (2011), Ranjan K (2016), Ranjan K (2016)	6
FYN	1	CAV1	0	biochemical	Mastick CC (1997)	1
ATP6V0B	1	FAS	2	two hybrid	Wang J (2011)	1
FAS	2	ALDH1L2	1	affinity chromatography technology	Huttlin EL (2015)	1
TNF	0	SFXN5	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	COX16	0	affinity chromatography technology	Huttlin EL (2015)	1
PRKCA	7	CTNNB1	30	affinity chromatography technology	Mertz JA (2011)	1
PRKAG1	1	FAS	2	affinity chromatography technology	Huttlin EL (2015)	1
TNF	0	CAV1	0	affinity chromatography technology	Legler DF (2003)	1
RAP1A	1	ARHGDIA	3	biochemical	Wan C (2015)	1
MDN1	19	TUBB3	3	biochemical	Havugimana PC (2012)	1
RARA	5	LRIF1	3	two hybrid, far western blotting, pull down	Li HJ (2007), Li HJ (2007), Li HJ (2007)	3
TNFRSF1A	3	CAV1	0	biochemical	Legler DF (2003)	1
FAS	2	ERG28	0	two hybrid	Stelzl U (2005)	1
BAG6	2	TP63	0	two hybrid	Wang J (2011)	1
FASLG	0	YES1	1	unspecified method	Voss M (2009)	1
BID	1	ERG28	0	two hybrid	Vinayagam A (2011)	1
FAS	2	WDR11	4	affinity chromatography technology	Huttlin EL (2015)	1
CASP8AP2	3	FAS	2	affinity chromatography technology	Imai Y (1999)	1
HIPK3	5	FADD	1	affinity chromatography technology	Rochat-Steiner V (2000)	1
RARA	5	SRC	2	two hybrid, two hybrid	He B (2003), Lee HK (2007)	2
CASP8	1	CFLAR	1	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Micheau O (2003), Shu HB (1997), Goltsev YV (1997), Srinivasula SM (1997), Srinivasula SM (1997), Srinivasula SM (1997), Micheau O (2002), Han DK (1997), Han DK (1997), Han DK (1997), Roth W (2002), Zhang L (2009), Tenev T (2011), Kerr E (2012), Sinha SK (2004), Lee EW (2012), Rebe C (2007), Rebe C (2007), Kaunisto A (2009), Feoktistova M (2011), Feoktistova M (2011), Huttlin EL (2015), Huttlin EL (2017)	23
FAS	2	TUBB3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	RIPK1	2	two hybrid	Stanger BZ (1995)	1
FAS	2	HNRNPC	0	two hybrid	Wang J (2011)	1
RB1	2	CCND3	1	two hybrid, affinity chromatography technology, pull down	Stern MD (2007), Bockstaele L (2006), Jaenicke RU (1996)	3
CASP10	1	FADD	1	biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, pull down, pull down	Gajate C (2005), Vincenz C (1997), Vincenz C (1997), Srinivasula SM (1997), Srinivasula SM (1997), Wang J (2001), McDonald ER (2004), Choi H (2011), Choi H (2011)	9
ARHGDIA	3	CASP8	1	biochemical	Gajate C (2005)	1
PML	7	RARA	5	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhong S (1999), Zhong S (1999), Minucci S (2000), Kraemer OH (2008), Wang K (2010), Wang K (2010), Cote S (2000), Bellodi C (2006), Villa R (2007)	9
BID	1	FADD	1	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
BID	1	TUBB2B	2	two hybrid	Vinayagam A (2011)	1
TNFRSF10B	1	RIPK1	2	affinity chromatography technology, affinity chromatography technology	Chaudhary PM (1997), Bellail AC (2012)	2
RHOBTB3	1	ARF5	0	affinity chromatography technology	Huttlin EL (2017)	1
FAS	2	MSN	0	biochemical	Gajate C (2005)	1
FAS	2	MBD4	1	two hybrid	Wang J (2011)	1
SQSTM1	0	CAV1	0	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Luo X (2017)	2
TRADD	0	NOL3	0	genetic interference	Koseki T (1998)	1
TNFRSF10B	1	TRADD	0	affinity chromatography technology	Chaudhary PM (1997)	1
FAS	2	SPATA5L1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ARHGDIA	3	BID	1	biochemical	Gajate C (2005)	1
TRAF3	1	MAP3K5	1	affinity chromatography technology	Nishitoh H (1998)	1
UBQLN1	1	PDCD6	2	biochemical	Wan C (2015)	1
FYN	1	TNF	0	pull down	Simms HH (1997)	1
FAS	2	SPATA5	7	affinity chromatography technology	Huttlin EL (2015)	1
RHOA	0	TNFRSF10B	1	biochemical	Gajate C (2005)	1
MAPK8	3	TNFRSF1A	3	biochemical	Gajate C (2005)	1
SQSTM1	0	RARA	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Z (2011), Wang Z (2011), Yang L (2015), Yang L (2015)	4
FADD	1	TNFRSF10B	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Chaudhary PM (1997), Kim Y (2002), Guo F (2005), Gonzalvez F (2012), Huttlin EL (2015), Huttlin EL (2017), Xu L (2017)	8
FAF1	1	FADD	1	pull down, affinity chromatography technology	Ryu SW (2003), Ryu SW (2003)	2
RHOA	0	TNFRSF1A	3	biochemical	Gajate C (2005)	1
FAS	2	FAM118B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EZR	8	FASLG	0	biochemical, affinity chromatography technology	Gajate C (2005), Parlato S (2000)	2
TUBB2A	2	TUBB3	3	affinity chromatography technology	Huttlin EL (2017)	1
FAS	2	ABHD11	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RHOA	0	FASLG	0	biochemical	Gajate C (2005)	1
FASLG	0	LCK	0	pull down	Wenzel J (2001)	1
UBE2I	0	CASP8AP2	3	two hybrid, enzymatic study	Bandyopadhyay S (2010), Gocke CB (2005)	2
FAS	2	ACAD9	1	affinity chromatography technology	Huttlin EL (2015)	1
FAS	2	NOL3	0	genetic interference	Koseki T (1998)	1
CAV1	0	SRC	2	pull down	Li S (1996)	1
TP63	0	UBE2I	0	two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study	Huang YP (2004), Huang YP (2004), Huang YP (2004), Ghioni P (2005)	4
BAG6	2	FAF2	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu Y (2012), Xu Y (2013), Xu Y (2013), Raman M (2015)	4
FAF2	4	ACAD9	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Raman M (2015), Huttlin EL (2017)	3
FAS	2	ARF5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD4	1	FADD	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Screaton RA (2003), Screaton RA (2003), Screaton RA (2003)	3
UBQLN1	1	BAG6	2	affinity chromatography technology, affinity chromatography technology	Kurlawala Z (2017), Kurlawala Z (2017)	2
FAS	2	TNFRSF1A	3	biochemical	Gajate C (2005)	1
FAS	2	FAF1	1	affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology	Chu K (1995), Ryu SW (1999), Ryu SW (1999), Imai Y (2002), Ryu SW (2003)	5
FAS	2	CASP8	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Shu HB (1997), MacFarlane M (1997), Huttlin EL (2015), Jeong M (2017), Huttlin EL (2017), Kleber S (2008)	7
TNFRSF1A	3	FYN	1	biochemical	Legler DF (2003)	1
RARA	5	PRAM1	4	affinity chromatography technology	Tao RH (2011)	1
SUMO1	0	TP63	0	affinity chromatography technology	Huang YP (2004)	1
UBE2I	0	TRAF3	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Miliara S (2013), Miliara S (2013), Miliara S (2013), Miliara S (2013)	4
FAS	2	BID	1	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
SPATA5	7	SPATA5L1	2	affinity chromatography technology, affinity chromatography technology	Blomen VA (2015), Huttlin EL (2017)	2
FAS	2	C17orf75	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HNRNPC	0	SUMO1	0	two hybrid	Rolland T (2014)	1
CFLAR	1	FADD	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shu HB (1997), Srinivasula SM (1997), Srinivasula SM (1997), Srinivasula SM (1997), Srinivasula SM (1997), Srinivasula SM (1997), Han DK (1997), Kerr E (2012), Rebe C (2007), Choi H (2011), Feoktistova M (2011), Ranjan K (2016), Jeong M (2017)	13
FADD	1	TRADD	0	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henshall DC (2003), Hsu H (1996), Hsu H (1996), Thomas LR (2002), Guan YJ (2011), Park KJ (2003), Qi Z (2014)	7
MSN	0	TNFRSF1A	3	biochemical	Gajate C (2005)	1
CAV1	0	BID	1	affinity chromatography technology, affinity chromatography technology	Zhang M (2011), Zhang M (2011)	2
TP63	0	FAS	2	affinity chromatography technology	Amoresano A (2010)	1
SUMO1	0	FAS	2	two hybrid, pull down	Okura T (1996), Okura T (1996)	2
FAF1	1	BAG6	2	affinity chromatography technology	Baron Y (2014)	1
BAG6	2	TUBB3	3	affinity chromatography technology	Hein MY (2015)	1
TNFRSF1A	3	PIK3R1	6	affinity chromatography technology	Pincheira R (2008)	1
FAS	2	RUFY1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FADD	1	DAXX	5	affinity chromatography technology	Meinecke I (2007)	1
FADD	1	FASLG	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Gajate C (2005), Micheau O (2003), Legler DF (2003), Tao RH (2011), Chen TC (2014)	5
TMX1	4	UFSP2	1	affinity chromatography technology	Huttlin EL (2017)	1
FASLG	0	TNFRSF10B	1	biochemical	Gajate C (2005)	1
CASP10	1	RB1	2	enzymatic study	Lemaire C (2005)	1
MSN	0	CASP10	1	biochemical	Gajate C (2005)	1
FAS	2	CFLAR	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shu HB (1997), MacFarlane M (1997), Jeong M (2017)	3
CASP10	1	TNFRSF1A	3	biochemical, affinity chromatography technology	Gajate C (2005), Vincenz C (1997)	2
TRAF3	1	SRC	2	affinity chromatography technology, affinity chromatography technology	Wong BR (1999), Johnsen IB (2009)	2
FYN	1	TNFRSF10B	1	affinity chromatography technology	Huttlin EL (2017)	1
FAS	2	EEF1A1	0	two hybrid	Stelzl U (2005)	1
RHOA	0	EZR	8	biochemical	Gajate C (2005)	1
MAPK8	3	FADD	1	biochemical	Gajate C (2005)	1
ARHGDIA	3	TNFRSF1A	3	biochemical	Gajate C (2005)	1
UBE2I	0	DAXX	5	two hybrid, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, two hybrid	Ryu SW (2000), Knipscheer P (2008), Hsieh YL (2013), Hsieh YL (2013), Hsieh YL (2013), Chang CC (2011), Lin DY (2006), Lin DY (2006)	8
RHOA	0	MSN	0	biochemical	Gajate C (2005)	1
CASP8AP2	3	CASP8	1	affinity chromatography technology	Imai Y (1999)	1
TNFRSF1A	3	SRC	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Narita T (2005), Pincheira R (2008), Darnay BG (1997)	3
BAG6	2	FAS	2	two hybrid	Wang J (2011)	1
CASP8	1	TNFRSF10B	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), MacFarlane M (1997), Kim Y (2002), Kaunisto A (2009), Kaunisto A (2009), Guo F (2005), Gonzalvez F (2012), Gonzalvez F (2012), Huttlin EL (2015), Huttlin EL (2017), Xu L (2017), Xu L (2017)	12
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
TNFRSF1A	3	DAXX	5	two hybrid, pull down	Yang X (1997), Yang X (1997)	2
UBE2I	0	ARHGDIA	3	enzymatic study	Kuhlmann N (2016)	1
PIK3R1	6	EZR	8	affinity chromatography technology, pull down	Gautreau A (1999), Gautreau A (1999)	2
FAS	2	TNFRSF10B	1	biochemical	Gajate C (2005)	1
GADD45A	1	ERG28	0	two hybrid	Vinayagam A (2011)	1
RAP1A	1	FAS	2	pull down, imaging technique	Stoletov KV (2004), Chen TC (2014)	2
BID	1	MAPK8	3	biochemical	Gajate C (2005)	1
DAXX	5	CFLAR	1	affinity chromatography technology, affinity chromatography technology	Kim YY (2003), Kim YY (2003)	2
FYN	1	FAS	2	affinity chromatography technology	Atkinson EA (1996)	1
FAS	2	FAM91A1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RAP1A	1	FAF1	1	pull down	Stoletov KV (2004)	1
FAS	2	PDXDC1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2I	0	HIPK3	5	two hybrid	Bandyopadhyay S (2010)	1
NOL3	0	DAXX	5	affinity chromatography technology, affinity chromatography technology	Donath S (2016), Donath S (2016)	2
EZR	8	FADD	1	biochemical, affinity chromatography technology, imaging technique	Gajate C (2005), Young JA (2011), Chen TC (2014)	3
FADD	1	TNFRSF1A	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Hsu H (1996), Kumar A (2001), Zheng L (2006)	4
CASP8	1	NOL3	0	genetic interference, affinity chromatography technology	Koseki T (1998), Koseki T (1998)	2
HNRNPC	0	TRAF3	1	unspecified method	Schultz AS (2017)	1
TMX1	4	EHD1	5	affinity chromatography technology	Huttlin EL (2017)	1
TNFRSF1A	3	UBQLN1	1	two hybrid	Wang J (2011)	1
MAPK8	3	TNFRSF10B	1	biochemical	Gajate C (2005)	1
ACAD9	1	NDUFAF1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guarani V (2014), Guarani V (2014), Nouws J (2010), Nouws J (2010), Huttlin EL (2017)	5
ARHGDIA	3	CASP10	1	biochemical	Gajate C (2005)	1
FAS	2	RHOA	0	biochemical, imaging technique	Gajate C (2005), Chen TC (2014)	2
RIPK1	2	TNFRSF1A	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim JW (2000), Duan H (1997), Hsu H (1996), Blankenship JW (2009), Newton K (2008), Varfolomeev E (2008), Fearns C (2006), Vince JE (2009), Dynek JN (2010), Kim S (2010), Cheung HH (2009), Tenev T (2011), Mahul-Mellier AL (2011), Won M (2010), Glowacka WK (2012), Fan YH (2011), Cusson-Hermance N (2005), ODonnell MA (2012), Zheng L (2006), Vince JE (2007), Mitsuhashi S (2008), Kim TW (2013), Wertz IE (2004), Liao W (2008), Wang YB (2015), Chang YL (2014), Zilberman-Rudenko J (2016), Zemirli N (2014), Moquin DM (2013), Nakazawa S (2016), Jeong M (2017), Huttlin EL (2017), Elliott PR (2016)	33
FAS	2	EHD1	5	affinity chromatography technology	Huttlin EL (2015)	1
FAS	2	PRAM1	4	affinity chromatography technology	Tao RH (2011)	1
FAF2	4	TIMM29	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MSN	0	EZR	8	biochemical, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Gajate C (2005), Gary R (1995), Gary R (1993), Gary R (1993), Hein MY (2015)	5
FAS	2	LRIF1	3	two hybrid	Stelzl U (2005)	1
FAS	2	RB1	2	affinity chromatography technology	Huttlin EL (2015)	1
FAS	2	TUBB2B	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MSN	0	TNFRSF10B	1	biochemical	Gajate C (2005)	1
KRIT1	1	RAP1A	1	two hybrid	Serebriiskii I (1997)	1
FAS	2	FBF1	2	two hybrid	Schmidt T (2000)	1
FAS	2	INTS2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FAS	2	ECSIT	3	affinity chromatography technology	Huttlin EL (2015)	1
MSN	0	MAPK8	3	biochemical	Gajate C (2005)	1
TNFRSF1A	3	NOL3	0	genetic interference	Koseki T (1998)	1
CTNNB1	30	PIK3R1	6	pull down, imaging technique	Espada J (1999), Chen TC (2014)	2
APOA5	1	FAS	2	two hybrid	Wang J (2011)	1
FAS	2	MOCS3	0	affinity chromatography technology	Huttlin EL (2015)	1
FADD	1	NOL3	0	genetic interference	Koseki T (1998)	1
TNF	0	CDYL	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FASLG	0	TNFRSF1A	3	biochemical, affinity chromatography technology	Gajate C (2005), Legler DF (2003)	2
FAS	2	FASLG	0	biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Gajate C (2005), Micheau O (2003), Starling GC (1997), Schneider P (1997), Legler DF (2003), Tao RH (2011), Chen TC (2014)	7
FAS	2	SFXN5	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CAV1	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Li Y (2008), Rodriguez DA (2009)	2
CCND3	1	FAS	2	two hybrid	Wang J (2011)	1
FAS	2	UGDH	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CAV1	0	TRADD	0	affinity chromatography technology	Feng X (2001)	1
TRADD	0	RIPK1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hsu H (1996), Hsu H (1996), Hsu H (1996), Ea CK (2006), Guan YJ (2011), Jeon J (2014), Lin B (2016)	7
TRAF3	1	RIPK1	2	affinity chromatography technology	Hsu H (1996)	1
FAS	2	CDYL	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BABAM2	2	TNFRSF1A	3	affinity chromatography technology, affinity chromatography technology	Li Q (2004), Li Q (2004)	2
TP63	0	DPH1	7	affinity chromatography technology	Lunardi A (2010)	1
CASP10	1	CFLAR	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	Micheau O (2003), Goltsev YV (1997), Srinivasula SM (1997), Srinivasula SM (1997), Srinivasula SM (1997), Feoktistova M (2011), Chen TC (2014)	7
TNFRSF10B	1	CFLAR	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	MacFarlane M (1997), Kim Y (2002), Kaunisto A (2009), Gonzalvez F (2012)	4
EZR	8	TNFRSF10B	1	biochemical	Gajate C (2005)	1
ARHGDIA	3	FASLG	0	biochemical	Gajate C (2005)	1
UBE2I	0	SUMO1	0	affinity chromatography technology, pull down, two hybrid, two hybrid, fluorescent resonance energy transfe, pull down, two hybrid, two hybrid, pull down, pull down, two hybrid, pull down, fluorescent resonance energy transfe, pull down, two hybrid, pull down, pull down, enzymatic study, enzymatic study, biochemical, affinity chromatography technology	Ewing RM (2007), Tatham MH (2003), Minty A (2000), Shen Z (1996), Song Y (2011), Knipscheer P (2007), Boutell C (2011), Gong L (1997), Gong L (1997), Hemelaar J (2004), Hecker CM (2006), Hecker CM (2006), Martin SF (2008), Everett RD (2014), Rolland T (2014), Zilio N (2013), Carbia-Nagashima A (2007), Knipscheer P (2007), Matic I (2008), Wan C (2015), Hein MY (2015)	21
FYN	1	CTNNB1	30	enzymatic study, imaging technique	Piedra J (2003), Chen TC (2014)	2
EZR	8	BID	1	biochemical	Gajate C (2005)	1
CAV1	0	FAS	2	affinity chromatography technology, affinity chromatography technology	Zhang M (2011), Zhang M (2011)	2
FAIM2	2	FAS	2	affinity chromatography technology	Somia NV (1999)	1
GADD45A	1	BAG6	2	two hybrid	Vinayagam A (2011)	1
FAS	2	GADD45A	1	two hybrid	Wang J (2011)	1
MSN	0	CTNNB1	30	biochemical	Wan C (2015)	1
CASP8AP2	3	PML	7	two hybrid	Wang J (2011)	1
FAF2	4	YES1	1	biochemical	Havugimana PC (2012)	1
FAS	2	GPD1L	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NDUFAF1	0	ECSIT	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vogel RO (2007), Vogel RO (2007), Huttlin EL (2015), Guarani V (2014), Guarani V (2014), Nouws J (2010), Nouws J (2010), Huttlin EL (2017)	8
ALDH1L2	1	WDR11	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ARHGDIA	3	FADD	1	biochemical	Gajate C (2005)	1
FAS	2	PDCD6	2	two hybrid, affinity chromatography technology, pull down	Jung YS (2001), Jung YS (2001), Jung YS (2001)	3