Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ITIH3 rs2535629 AA clozapine efficacy yes Patients were treated for up to 26 weeks prior to assessment. Improvement was measured on the negative symptom Brief Psychiatric Rating Scale measure, but no association was seen in overall BPRS scores. Genotype AA is associated with increased response to clozapine in people with Schizophrenia as compared to genotypes AG + GG. 27396837 1448123760