PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NAB2	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
CHD4	22	CHD3	19	affinity chromatography technology, affinity chromatography technology, biochemical	Xue Y (1998), Xue Y (1998), Havugimana PC (2012)	3
NAB2	2	NAB1	1	affinity chromatography technology	Huttlin EL (2017)	1
KRTAP10-8	0	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
SCNM1	0	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
NAB1	1	EGR1	1	two hybrid, pull down, affinity chromatography technology	Russo MW (1995), Russo MW (1995), Huttlin EL (2017)	3
MDFI	1	PIN1	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
SCNM1	0	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
NEDD9	3	RBPMS	0	two hybrid	Rolland T (2014)	1
NAB2	2	TNIP1	1	affinity chromatography technology	Huttlin EL (2017)	1
NAB2	2	TTC19	0	two hybrid	Rolland T (2014)	1
NAB2	2	CCDC33	3	two hybrid	Rolland T (2014)	1
AES	2	RBPMS	0	two hybrid	Rolland T (2014)	1
PIN1	0	TNIP1	1	two hybrid, two hybrid	Wang J (2011), Rolland T (2014)	2
NAB2	2	NAB2	2	two hybrid	Rolland T (2014)	1
SCNM1	0	CCDC33	3	two hybrid	Rolland T (2014)	1
NAB2	2	391257	0	two hybrid	Rolland T (2014)	1
PIN1	0	KRT40	0	two hybrid	Rolland T (2014)	1
PIN1	0	JAKMIP2	3	two hybrid	Rolland T (2014)	1
EGR1	1	NAB2	2	two hybrid	Svaren J (1996)	1
NAB2	2	CHD4	22	affinity chromatography technology, affinity chromatography technology	Srinivasan R (2006), Srinivasan R (2006)	2
LENG1	2	KRT40	0	two hybrid	Rolland T (2014)	1
MCM7	5	NAB2	2	two hybrid	Rolland T (2014)	1
MAPK3	4	CUEDC2	0	enzymatic study	Zhang WN (2013)	1
NAB2	2	CWF19L2	2	two hybrid	Rolland T (2014)	1
MDFI	1	NAB2	2	two hybrid	Rolland T (2014)	1
NAB2	2	CUEDC2	0	affinity chromatography technology	Huttlin EL (2017)	1
NAB2	2	TCHP	0	two hybrid	Rolland T (2014)	1
TCHP	0	KRT40	0	two hybrid	Rolland T (2014)	1
PIN1	0	CCDC33	3	two hybrid	Rolland T (2014)	1
CCHCR1	2	POLD2	2	two hybrid	Wang J (2011)	1
PHF1	1	RBPMS	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
SCNM1	0	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
NAB2	2	JAKMIP2	3	two hybrid	Rolland T (2014)	1
NAB2	2	RFC5	2	two hybrid	Rolland T (2014)	1
NAB2	2	ZBED8	1	two hybrid	Rolland T (2014)	1
NAB2	2	ZMYND19	1	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
NME7	0	TCHP	0	two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Boldt K (2016)	3
LMNA	2	C9orf78	0	bioid	Roux KJ (2012)	1
AES	2	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
NAB2	2	TGIF2LY	0	two hybrid	Rolland T (2014)	1
DGCR6	0	AES	2	two hybrid	Corominas R (2014)	1
DGCR6	0	NOTCH2NL	1	two hybrid	Corominas R (2014)	1
NME7	0	CCHCR1	2	two hybrid	Rolland T (2014)	1
NAB2	2	C9orf78	0	affinity chromatography technology	Huttlin EL (2017)	1
NAB2	2	MORF4L1	1	two hybrid	Rolland T (2014)	1
CCHCR1	2	KRT40	0	two hybrid	Rolland T (2014)	1
NAB2	2	TLN1	5	biochemical	Havugimana PC (2012)	1
KRT40	0	CWF19L2	2	two hybrid	Rolland T (2014)	1
NAB2	2	LENG1	2	two hybrid	Rolland T (2014)	1
NAB2	2	PHOSPHO2	0	two hybrid	Rolland T (2014)	1
MORF4L1	1	LMNA	2	affinity chromatography technology, two hybrid	Hayakawa T (2007), Dittmer TA (2014)	2
NAB2	2	CHD3	19	affinity chromatography technology	Srinivasan R (2006)	1
AES	2	KRT40	0	two hybrid	Rolland T (2014)	1
NAB2	2	TCEANC	0	two hybrid	Rolland T (2014)	1
LMNA	2	TCEANC	0	two hybrid	Dittmer TA (2014)	1
AES	2	SCNM1	0	two hybrid	Rolland T (2014)	1
NAB2	2	KRT40	0	two hybrid	Rolland T (2014)	1
NAB2	2	NBEA	15	affinity chromatography technology	Huttlin EL (2017)	1
AES	2	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
NAB2	2	VBP1	0	biochemical	Havugimana PC (2012)	1
KRTAP10-3	1	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
NAB2	2	GCC1	1	two hybrid	Rolland T (2014)	1
NAB2	2	PHF1	1	two hybrid	Rolland T (2014)	1
CCDC33	3	MDFI	1	two hybrid	Xin X (2009)	1
NAB2	2	NME7	0	two hybrid	Rolland T (2014)	1
GRN	2	CCDC33	3	two hybrid	Rolland T (2014)	1
AES	2	NAB2	2	two hybrid	Rolland T (2014)	1
LMNA	2	CWF19L2	2	two hybrid	Dittmer TA (2014)	1
TTC19	0	CCDC33	3	two hybrid	Rolland T (2014)	1
NAB2	2	GRN	2	affinity chromatography technology	Huttlin EL (2017)	1
NAB2	2	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
DGCR6	0	CCDC33	3	two hybrid	Corominas R (2014)	1
NAB2	2	POLD2	2	affinity chromatography technology	Huttlin EL (2017)	1
PIN1	0	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
LMNA	2	NAB2	2	two hybrid	Dittmer TA (2014)	1
DGCR6	0	NAB2	2	two hybrid	Corominas R (2014)	1
AES	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
NAB2	2	CCHCR1	2	two hybrid	Rolland T (2014)	1
NME7	0	TNIP1	1	two hybrid, two hybrid, two hybrid	Wang J (2011), Rolland T (2014), Yu H (2011)	3
NAB1	1	CHD4	22	affinity chromatography technology	Srinivasan R (2006)	1
TNIP1	1	MORF4L1	1	two hybrid	Rolland T (2014)	1
NAB2	2	RBPMS	0	two hybrid	Rolland T (2014)	1
LMNA	2	KRTAP10-3	1	two hybrid	Rolland T (2014)	1
NAB2	2	PIN1	0	two hybrid	Rolland T (2014)	1
EGR2	1	NAB2	2	enzymatic study	Garcia-Gutierrez P (2011)	1
KRTAP10-8	0	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
NAB2	2	NEDD9	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
NAB2	2	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
NAB2	2	SCNM1	0	two hybrid	Rolland T (2014)	1
PIN1	0	RBPMS	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
MAPK3	4	NAB2	2	two hybrid	Corominas R (2014)	1