PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PRKN	1	UBE2N	1	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Joch M (2007), Olzmann JA (2007), Chaugule VK (2011), Sha D (2010), Lim GG (2013), Durcan TM (2011), McKeon JE (2014), Sha D (2010)	8
HDAC6	0	ATM	9	affinity chromatography technology	New M (2013)	1
PRKN	1	UBE2D1	0	pull down	Kazlauskaite A (2014)	1
CDC5L	2	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
ATR	6	RPA2	0	enzymatic study, affinity chromatography technology	Olson E (2006), Marechal A (2014)	2
MSH2	4	ATM	9	biochemical	Wang Y (2000)	1
EP300	36	MRE11	3	affinity chromatography technology	Jung SY (2005)	1
MSH6	2	TOPBP1	5	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
EP300	36	TERF2	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Her YR (2013), Her YR (2013), Her YR (2013), Her YR (2013)	4
MDC1	8	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Xu X (2003), Goldberg M (2003), Goldberg M (2003), Stewart GS (2003), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	7
BARD1	4	MSH2	4	pull down	Wang Q (2001)	1
SIRT1	3	WRN	6	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Law IK (2009), Law IK (2009), Li K (2008), Li K (2008), Li K (2008), Li K (2008)	6
RPA1	0	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
PAXIP1	1	RPA1	0	two hybrid	Woods NT (2012)	1
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
RPA1	0	MRE11	3	affinity chromatography technology	Marechal A (2014)	1
SUMO2	0	ATRX	7	pull down	Ouyang J (2009)	1
ATRIP	1	ATR	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2003), Wang Y (2003), Cortez D (2004), Cortez D (2001), Cortez D (2001), Cortez D (2001), Cortez D (2001), Rendtlew Danielsen JM (2009), Kulkarni A (2008), Sivasubramaniam S (2008), Sivasubramaniam S (2008), Itakura E (2004), Itakura E (2004), Itakura E (2004), Pabla N (2008), Pabla N (2011), Collis SJ (2007), Collis SJ (2007), Warmerdam DO (2010), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Bomgarden RD (2004), Choi JH (2007), Lovejoy CA (2009), Huttlin EL (2017)	27
EP300	36	MDC1	8	affinity chromatography technology	Jung SY (2005)	1
PRKDC	12	ATM	9	unspecified method, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Suzuki K (1999), Suzuki K (1999)	3
NBN	1	UBE2A	0	affinity chromatography technology	Yanagihara H (2011)	1
ATR	6	RPA1	0	unspecified method, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Pabla N (2008), Marechal A (2014)	3
SNW1	0	VRK1	0	affinity chromatography technology	Lleres D (2010)	1
RPA3	2	RPA2	0	biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
BRCA1	7	RAD50	3	biochemical, biochemical, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Greenberg RA (2006), Chen L (2008), Hill SJ (2014), Acharya S (2014)	10
SIRT1	3	HSPA4	3	affinity chromatography technology	Law IK (2009)	1
CBX8	3	NCL	1	affinity chromatography technology	Vandamme J (2011)	1
HDAC6	0	NCL	1	affinity chromatography technology	Watson GW (2016)	1
PRKN	1	NBN	1	affinity chromatography technology	Zhu X (2017)	1
NBN	1	CASC3	0	two hybrid	Arroyo R (2015)	1
UBE2D1	0	NBN	1	pull down	Lu CS (2012)	1
PAXIP1	1	BLM	2	affinity chromatography technology	Cho YW (2007)	1
ATR	6	WRN	6	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Otterlei M (2006), Patro BS (2011), Patro BS (2011)	4
RPA3	2	TERF2	2	affinity chromatography technology	Marechal A (2014)	1
BRIP1	2	MSH2	4	genetic interference	Peng M (2014)	1
XRCC5	5	BARD1	4	affinity chromatography technology, affinity chromatography technology	Wei L (2008), Woods NT (2012)	2
RPA2	0	MED4	2	affinity chromatography technology	Marechal A (2014)	1
TERF1	1	IPO5	0	two hybrid	Lee OH (2011)	1
HDAC6	0	MRE11	3	affinity chromatography technology	Zhang M (2014)	1
BMI1	0	SNW1	0	affinity chromatography technology	Cao Q (2014)	1
DPPA4	0	NBN	1	affinity chromatography technology	Oliviero G (2015)	1
BRCA1	7	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Acharya S (2014), Ertych N (2016)	3
HIST1H3E	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology, biochemical	Drane P (2010), Shuaib M (2010), Campos EI (2015)	3
DDX1	6	RAD50	3	affinity chromatography technology	Li L (2008)	1
MTOR	14	PRKDC	12	genetic interference	Shen JP (2017)	1
RGS20	2	NBN	1	affinity chromatography technology	Huttlin EL (2017)	1
MRE11	3	MLH1	6	biochemical	Wang Y (2000)	1
MCPH1	4	NBN	1	imaging technique	Rai R (2006)	1
BARD1	4	BRIP1	2	unspecified method, affinity chromatography technology	Thanassoulas A (2010), Wu W (2016)	2
MRE11	3	RFC1	1	biochemical	Wang Y (2000)	1
BRCA1	7	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu Y (2012), Lu Y (2012), Parameswaran B (2015)	3
MDM2	2	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Nihira NT (2017), Nihira NT (2017), Nihira NT (2017)	3
BARD1	4	H2AFX	1	pull down	Mallery DL (2002)	1
HDAC6	0	MSH2	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	New M (2013), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014)	7
KAT5	1	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang J (2010), Wang J (2010), Yamagata K (2009), Yamagata K (2009), Peng L (2012)	5
UBE2D1	0	UBE2B	3	biochemical	Havugimana PC (2012)	1
PRKDC	12	WRN	6	unspecified method, affinity chromatography technology, enzymatic study	Kim ST (1999), Karmakar P (2002), Karmakar P (2002)	3
BLM	2	WRN	6	affinity chromatography technology, pull down	von Kobbe C (2002), von Kobbe C (2002)	2
HDAC6	0	RAD50	3	affinity chromatography technology	Zhang M (2014)	1
CHEK1	2	XRCC5	5	affinity chromatography technology	Goudelock DM (2003)	1
PRKDC	12	RPA2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Shao RG (1999), Shao RG (1999), Shao RG (1999), Wu X (2006), Zernik-Kobak M (1997), Chan DW (2000), Marechal A (2014), Fried LM (1996)	8
BLM	2	TERF2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Opresko PL (2002), Bhattacharyya S (2009), Lillard-Wetherell K (2004), Lillard-Wetherell K (2004)	4
CCNE1	1	SKP2	2	pull down, enzymatic study	Yeh KH (2001), Enchev RI (2012)	2
RPA1	0	RPA2	0	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017)	13
BMI1	0	NCL	1	affinity chromatography technology	Cao Q (2014)	1
PAXIP1	1	CDC5L	2	affinity chromatography technology	Woods NT (2012)	1
RAD50	3	RNF8	2	affinity chromatography technology	Lu CS (2012)	1
BRCA1	7	TOPBP1	5	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Greenberg RA (2006), Mok MT (2010), Tian F (2013), Hill SJ (2014), Sakasai R (2012)	5
MSH2	4	MLH1	6	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Wang Y (2000), Matton N (2000), Plotz G (2003), Plotz G (2003), Chen TC (2014)	5
ATR	6	NBN	1	unspecified method, pull down, affinity chromatography technology	Kim ST (1999), Falck J (2005), Falck J (2005)	3
ATRX	7	RPA1	0	affinity chromatography technology	Leung JW (2013)	1
PAXIP1	1	NBN	1	affinity chromatography technology	Cho YW (2007)	1
CCNE1	1	TUBG1	2	biochemical	Matsumoto Y (2004)	1
POU5F1	0	NBN	1	affinity chromatography technology	Oliviero G (2015)	1
BMP1	5	RAD50	3	affinity chromatography technology	Huttlin EL (2017)	1
NBN	1	SNAI1	1	two hybrid	Arroyo R (2015)	1
ATM	9	TERF2	2	affinity chromatography technology, pull down	Karlseder J (2004), Karlseder J (2004)	2
SNW1	0	UBE2N	1	affinity chromatography technology	Lleres D (2010)	1
SKP2	2	OFD1	3	affinity chromatography technology	Huttlin EL (2017)	1
MCM9	1	MSH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Hutchins JR (2016), Traver S (2015), Traver S (2015), Traver S (2015), Traver S (2015)	5
CBX8	3	KAT5	1	two hybrid, affinity chromatography technology	Stelzl U (2005), Tan J (2011)	2
POU5F1	0	CDC5L	2	affinity chromatography technology	Oliviero G (2015)	1
HDAC6	0	MSH6	2	affinity chromatography technology, affinity chromatography technology	Zhang M (2014), Zhang M (2014)	2
ATM	9	RBBP8	1	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Li S (2000), Li S (2000), Kim ST (1999), Li S (2000)	4
TERF2	2	NCL	1	two hybrid	Lee OH (2011)	1
BRIP1	2	MRE11	3	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down	Suhasini AN (2013), Suhasini AN (2013), Suhasini AN (2013), Suhasini AN (2013), Suhasini AN (2013)	5
BLM	2	ATRX	7	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Srivastava V (2009), Srivastava V (2009), Srivastava V (2009), Srivastava V (2009)	4
ATM	9	CHEK1	2	unspecified method, enzymatic study, genetic interference	Kim ST (1999), Sorensen CS (2003), Shen JP (2017)	3
NANOG	0	XRCC5	5	affinity chromatography technology	Oliviero G (2015)	1
EP300	36	UBE2D1	0	pull down, pull down	Shi D (2009), Grossman SR (2003)	2
BARD1	4	MLH1	6	biochemical	Greenberg RA (2006)	1
TERF2	2	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	OConnor MS (2004), OConnor MS (2004), OConnor MS (2004), Li B (2000), Zhu XD (2000), Zhu XD (2000), Chen Y (2011), Chen Y (2011), Chen Y (2011), Chen Y (2011), Liu D (2004), Liu D (2004), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Her YR (2009), Havugimana PC (2012), Her YR (2013), Wan C (2015), Hein MY (2015), Her J (2015), Arat N Oe (2012), Li JS (2017), Jeong YY (2016), Ilic A (2017), Ilic A (2017)	28
SKP2	2	NBN	1	affinity chromatography technology, affinity chromatography technology	Wu J (2012), Wu J (2012)	2
RNF8	2	MDC1	8	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Huen MS (2007), Mailand N (2007), Mailand N (2007), Kolas NK (2007), Kolas NK (2007), Watanabe S (2013), Henriksson S (2014), Henriksson S (2014), Rassoolzadeh H (2015)	9
BMI1	0	ATRX	7	affinity chromatography technology, biochemical	Abdouh M (2016), Abdouh M (2016)	2
FANCD2	3	BRCA1	7	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reuter TY (2003), Vandenberg CJ (2003), Garcia-Higuera I (2001), Garcia-Higuera I (2001), Loke J (2015)	5
RAD50	3	MLH1	6	biochemical	Wang Y (2000)	1
OFD1	3	IPO5	0	affinity chromatography technology	Gupta GD (2015)	1
CDC5L	2	CHEK1	2	affinity chromatography technology	Lleres D (2010)	1
LZTS2	4	CD3EAP	3	affinity chromatography technology	Huttlin EL (2017)	1
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
UBE2A	0	MRE11	3	affinity chromatography technology	An H (2017)	1
ATR	6	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down	Stauffer D (2007), Stauffer D (2007), Stauffer D (2007)	3
ATF2	1	H2AFX	1	affinity chromatography technology	Bhoumik A (2008)	1
ATR	6	MRE11	3	unspecified method	Kim ST (1999)	1
SNW1	0	RAD50	3	affinity chromatography technology	Lleres D (2010)	1
BARD1	4	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down	Mallery DL (2002), Dong Y (2003), Wu-Baer F (2003), Hashizume R (2001), Nhukeaw T (2014), Thakar A (2010)	6
HIF1A	1	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kong X (2006), Qian DZ (2006), Kong X (2006), Zhou J (2004), Zhou J (2004), van de Sluis B (2009), Luo W (2010), Luo W (2010), Luo W (2010), Bento CF (2010), Katschinski DM (2004), Sun H (2013)	12
CDC5L	2	TUBG1	2	affinity chromatography technology	Lleres D (2010)	1
MDC1	8	MDM2	2	unspecified method, affinity chromatography technology	Rodriguez M (2003), Inoue K (2008)	2
SIRT1	3	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology	Lim JH (2010), Lim JH (2010), Lim JH (2010)	3
DDX1	6	NBN	1	affinity chromatography technology	Li L (2008)	1
TOPBP1	5	BLM	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013)	7
ATM	9	MRE11	3	unspecified method, biochemical, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Falck J (2005)	3
PRKDC	12	MRE11	3	unspecified method	Kim ST (1999)	1
KAT5	1	HIST3H3	0	unspecified method, pull down	Sun Y (2009), Sun Y (2009)	2
BRCA1	7	H2AFX	1	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, enzymatic study, affinity chromatography technology, imaging technique	Mallery DL (2002), Paull TT (2000), Ray A (2009), Tsai WB (2008), Mok MT (2010), Nelson AC (2010), Chen A (2002), Dutta D (2015), Dutta D (2015)	9
POU5F1	0	ATR	6	affinity chromatography technology	Oliviero G (2015)	1
POU5F1	0	MRE11	3	affinity chromatography technology	Oliviero G (2015)	1
MDM2	2	UBE2N	1	pull down	David Y (2011)	1
SNAI1	1	HIST1H3A	3	affinity chromatography technology	Lin Y (2010)	1
RPA2	0	NCL	1	affinity chromatography technology	Marechal A (2014)	1
UBE2A	0	UBE2B	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hong JH (2015), Hong JH (2015), Huttlin EL (2017)	3
RBBP8	1	FANCD2	3	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, genetic interference, imaging technique, affinity chromatography technology	Yeo JE (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014)	12
MDM4	0	EP300	36	pull down	Kadakia M (2002)	1
MCPH1	4	MDC1	8	imaging technique	Rai R (2006)	1
HIST1H3E	0	HSPA4	3	biochemical	Campos EI (2015)	1
H2AFX	1	HIST1H3A	3	affinity chromatography technology, imaging technique	Lee HS (2010), Soldi M (2013)	2
ATRX	7	MRE11	3	affinity chromatography technology, affinity chromatography technology	Leung JW (2013), Huh MS (2016)	2
SKP2	2	RAD50	3	affinity chromatography technology	Wu J (2012)	1
NBN	1	BAP1	4	two hybrid	Arroyo R (2015)	1
SIRT1	3	HIST1H3A	3	enzymatic study	Das C (2009)	1
BRCA1	7	DDX1	6	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	RFC1	1	biochemical, affinity chromatography technology	Wang Y (2000), Hill SJ (2014)	2
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
XRCC4	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Drouet J (2005)	2
RPA1	0	MSH2	4	affinity chromatography technology, biochemical	Marechal A (2014), Wan C (2015)	2
HIST1H3A	3	LIG3	6	bioid	Lambert JP (2015)	1
FANCD2	3	NBN	1	affinity chromatography technology	Nakanishi K (2002)	1
DCLRE1C	3	NBN	1	affinity chromatography technology	Zhang X (2004)	1
SNAI1	1	ATM	9	affinity chromatography technology	Liu T (2017)	1
MCM9	1	MSH6	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2016), Traver S (2015), Traver S (2015)	3
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
BRCA1	7	BAP1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Jensen DE (1998), Jensen DE (1998), Jensen DE (1998), Jensen DE (1998)	4
RECQL5	3	RAD50	3	affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009)	3
ATRX	7	MDM2	2	unspecified method	Li Z (2017)	1
SIRT1	3	MTOR	14	affinity chromatography technology, affinity chromatography technology	Back JH (2011), Singh BK (2016)	2
ATF2	1	MRE11	3	imaging technique	Bhoumik A (2005)	1
MTOR	14	PRKN	1	affinity chromatography technology	Park D (2014)	1
HDAC6	0	NBN	1	affinity chromatography technology	Zhang M (2014)	1
FAM219A	1	MRE11	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HIST1H3A	3	FANCD2	3	pull down, enzymatic study, pull down	Sato K (2012), Sato K (2012), Sato K (2012)	3
ATM	9	TOPBP1	5	affinity chromatography technology	Perfettini JL (2009)	1
TOPBP1	5	ATRIP	1	affinity chromatography technology	Venere M (2007)	1
SNAI1	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lim SO (2011), Lim SO (2010), Lim SO (2010)	3
SKP2	2	RICTOR	4	affinity chromatography technology	Huttlin EL (2017)	1
BLM	2	RPA1	0	pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brosh RM (2000), Opresko PL (2002), Moens PB (2002), Meetei AR (2003), Meetei AR (2003), Meetei AR (2003), Wang J (2013), Marechal A (2014), Chaudhury I (2014), Elia AE (2015)	10
MDM4	0	MDM2	2	pull down, two hybrid, enzymatic study, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, two hybrid, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, two hybrid, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Kadakia M (2002), Tanimura S (1999), Badciong JC (2002), Tanimura S (1999), Tanimura S (1999), Linke K (2008), Okamoto K (2005), Pan Y (2003), Kashuba E (2011), Kashuba E (2011), Ohtsubo C (2009), Singh RK (2007), Zhu Y (2009), Zhu Y (2009), Allende-Vega N (2010), Okamoto K (2009), Okamoto K (2009), Li X (2011), Nie J (2010), Nie J (2010), Li M (2011), Li M (2011), Singh RK (2007), de Graaf P (2003), Wade M (2012), Uldrijan S (2007), Wade M (2012), Stad R (2000), Dolezelova P (2012), Kulikov R (2005), Kawai H (2007), Kawai H (2007), Miller KR (2010), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Li C (2002), Wu S (2012), Ranaweera RS (2013), Woodsmith J (2012), Wang J (2011), Egorova O (2014), Chang YS (2013), Malbert-Colas L (2014), Yasuhara T (2014), Yasuhara T (2014), Iyappan S (2010), Stad R (2001), Marcar L (2015), Ling X (2014), Leslie PL (2015), Jacob AG (2014), Jacob AG (2014), Tournillon AS (2015), Tournillon AS (2015), Tournillon AS (2015), Zhang H (2015), Chen L (2015), Pellegrino M (2015), Pellegrino M (2015), Pellegrino M (2015), Medina-Medina I (2016), Medina-Medina I (2016), Moscetti I (2016), Liu T (2017), Liu T (2017), Liu T (2017), Huttlin EL (2017), Wu W (2015), Ivanov AA (2017), Mancini F (2016), Mancini F (2016)	74
FANCD2	3	BLM	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pichierri P (2004), Pichierri P (2004), Chaudhury I (2014)	3
MDC1	8	NCL	1	pull down	Kobayashi J (2012)	1
PRKDC	12	FANCD2	3	genetic interference	Aggarwal M (2013)	1
MDC1	8	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, pull down, affinity chromatography technology, imaging technique	Xu X (2003), Goldberg M (2003), Goldberg M (2003), Lukas C (2004), Cha H (2010), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Lou Z (2004), Hari FJ (2010), Lu CS (2012), Wu L (2008), Wu L (2008), Wu L (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	18
BMP1	5	NBN	1	affinity chromatography technology	Huttlin EL (2017)	1
TUBG1	2	HSPA4	3	biochemical	Wigley WC (1999)	1
SNW1	0	MSH6	2	affinity chromatography technology	Lleres D (2010)	1
XRCC5	5	NCL	1	biochemical	Kristensen AR (2012)	1
WRN	6	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Orren DK (2001), Li B (2004), Li B (2004), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Partridge JJ (2003), Partridge JJ (2003), Hein MY (2015)	14
MSH2	4	MSH6	2	biochemical, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, biochemical, affinity chromatography technology, imaging technique	Wang Y (2000), Wang Y (2003), Guerrette S (1998), Bocker T (1999), Bocker T (1999), Acharya S (1996), Matton N (2000), Matton N (2000), Yang Q (2004), Havugimana PC (2012), Gradia S (1997), Owen BA (2009), Wan C (2015), Hein MY (2015), Chen TC (2014)	15
ATRX	7	WRN	6	far western blotting	Otterlei M (2006)	1
MCPH1	4	ATM	9	imaging technique	Rai R (2006)	1
BRIP1	2	HIST1H3A	3	affinity chromatography technology	Wu W (2016)	1
MDM2	2	MRE11	3	affinity chromatography technology, affinity chromatography technology	Alt JR (2005), Alt JR (2005)	2
ATR	6	TOPBP1	5	affinity chromatography technology	Rendtlew Danielsen JM (2009)	1
CDC5L	2	FANCD2	3	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	BACH1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cantor SB (2001), Cantor SB (2001), Kumaraswamy E (2007), Kumaraswamy E (2007), Shiozaki EN (2004), Shiozaki EN (2004), Greenberg RA (2006), Greenberg RA (2006), Sy SM (2009), Wang B (2007), Wang B (2007), Wang B (2007), Botuyan MV (2004), Botuyan MV (2004), Hu Y (2014)	15
RNF8	2	BARD1	4	affinity chromatography technology	Yang Q (2016)	1
PHRF1	7	XRCC5	5	affinity chromatography technology	Chang CF (2015)	1
POU5F1	0	DPPA4	0	affinity chromatography technology	Oliviero G (2015)	1
RPA1	0	WRN	6	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Elia AE (2015)	2
CHEK1	2	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference	Yarden RI (2002), Yarden RI (2002), Inoue Y (2007), Shen JP (2017)	4
EP300	36	HDAC6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Han Y (2009), Han Y (2009), Liu Y (2012), Kirilyuk A (2012), Girdwood D (2003)	5
FANCD2	3	H2AFX	1	affinity chromatography technology, affinity chromatography technology	Bogliolo M (2007), Bogliolo M (2007)	2
NANOG	0	MRE11	3	affinity chromatography technology	Oliviero G (2015)	1
CHEK1	2	RFC1	1	genetic interference	Srivas R (2016)	1
TERF2IP	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), OConnor MS (2004), Liu D (2004)	3
MDC1	8	ATM	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Xu X (2003), Kolas NK (2007), Stewart GS (2003), Stewart GS (2003), Rassoolzadeh H (2015)	5
ATRX	7	H2AFX	1	imaging technique	Choi EH (2017)	1
BRCA1	7	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian F (2013), Tian F (2013), Hill SJ (2014)	3
EP300	36	PRKDC	12	pull down	Karmakar S (2010)	1
BRIP1	2	RAD50	3	affinity chromatography technology, affinity chromatography technology	Suhasini AN (2013), Suhasini AN (2013)	2
DDX1	6	ATM	9	affinity chromatography technology, pull down	Li L (2008), Li L (2008)	2
RPA1	0	RFC1	1	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Elia AE (2015)	2
TERF2IP	1	HSPA4	3	affinity chromatography technology	Liu D (2004)	1
NBN	1	RNF8	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Lu CS (2012), Lu CS (2012), Monsalve DM (2016)	3
MLH1	6	BRIP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cannavo E (2007), Xie J (2010), Xie J (2010), Xie J (2010), Peng M (2007), Peng M (2007), Peng M (2007), Peng M (2014), Mori R (2013), Guo M (2014)	10
SIRT1	3	RICTOR	4	enzymatic study, affinity chromatography technology	Glidden EJ (2012), Singh BK (2016)	2
XRCC5	5	NBN	1	affinity chromatography technology	Falck J (2005)	1
MSH2	4	ATR	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Wang Y (2003), Wang Y (2003), Wang Y (2003), Wang Y (2003), Pabla N (2011), Pabla N (2011), Pabla N (2011)	7
MRE11	3	RNF8	2	affinity chromatography technology	Lu CS (2012)	1
BACH1	3	TOPBP1	5	affinity chromatography technology	Greenberg RA (2006)	1
NBN	1	TUBG1	2	biochemical, affinity chromatography technology	Shimada M (2009), Shimada M (2009)	2
NBN	1	BRIP1	2	affinity chromatography technology	Suhasini AN (2013)	1
CCNE1	1	NBN	1	affinity chromatography technology	Stewart GS (2003)	1
PRKDC	12	RBBP8	1	unspecified method	Kim ST (1999)	1
KAT5	1	HIST1H3A	3	enzymatic study	Park JH (2010)	1
KAT5	1	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2002), Legube G (2002), Wu Q (2009), Dohmesen C (2008), Dohmesen C (2008), Kim JW (2008)	6
RNF8	2	BLM	2	enzymatic study, pull down	Tikoo S (2013), Tikoo S (2013)	2
FANCD2	3	TERF1	1	enzymatic study, imaging technique	Lyakhovich A (2011), Fan Q (2009)	2
RICTOR	4	MAPKAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Jacinto E (2006), Yang Q (2006), Jacinto E (2006), Pearce LR (2007), Pearce LR (2007), Gao D (2010), Gao D (2010), Oh WJ (2010), Oh WJ (2010), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Martin J (2008), Thedieck K (2007), Hong F (2008), Facchinetti V (2008), Chen CH (2011), Glidden EJ (2012), Thedieck K (2007)	24
HSPA4	3	MTOR	14	affinity chromatography technology, affinity chromatography technology	Martin J (2008), Martin J (2008)	2
BRIP1	2	BLM	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Suhasini AN (2011), Suhasini AN (2011), Suhasini AN (2011), Suhasini AN (2011), Sommers JA (2014)	5
MLH1	6	ATM	9	biochemical	Wang Y (2000)	1
RPA3	2	NCL	1	affinity chromatography technology	Marechal A (2014)	1
XRCC5	5	DCLRE1C	3	affinity chromatography technology, affinity chromatography technology	Drouet J (2006), Drouet J (2006)	2
POU5F1	0	NCL	1	affinity chromatography technology, affinity chromatography technology	Hawkins PG (2010), Johansson H (2010)	2
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
MSH6	2	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Yang Q (2004), Yang Q (2004)	3
BRCA1	7	TERF2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009), Hill SJ (2014)	3
BRCA1	7	NCL	1	affinity chromatography technology	Ertych N (2016)	1
RPA3	2	RAD50	3	affinity chromatography technology	Marechal A (2014)	1
SUMO2	0	NBN	1	pull down	Ouyang J (2009)	1
RPA2	0	CDC5L	2	affinity chromatography technology, pull down	Marechal A (2014), Marechal A (2014)	2
RPA2	0	LIG3	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Huttlin EL (2015), Huttlin EL (2017)	3
MSH6	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
SLX4	6	MSH2	4	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Svendsen JM (2009), Ghosal G (2012)	4
PRKDC	12	HIF1A	1	affinity chromatography technology	Um JH (2004)	1
RPA2	0	RAD50	3	affinity chromatography technology	Marechal A (2014)	1
RPA3	2	WRN	6	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Boldt K (2016)	2
MDC1	8	XRCC5	5	pull down, affinity chromatography technology	Lou Z (2004), Lou Z (2004)	2
NBN	1	TERF2IP	1	biochemical	Havugimana PC (2012)	1
MDC1	8	H2AFX	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, imaging technique	Stewart GS (2003), Stewart GS (2003), Xu X (2003), Lukas C (2004), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Pan MR (2011), Pei H (2011), Campbell SJ (2010), Rassoolzadeh H (2015)	13
BRCA1	7	RPA1	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Suhasini AN (2011), Mok MT (2010), Tian F (2013)	3
PRKN	1	BACH1	3	affinity chromatography technology	Zenke-Kawasaki Y (2007)	1
POU5F1	0	MSH6	2	affinity chromatography technology	Oliviero G (2015)	1
ATF2	1	BACH1	3	fluorescent resonance energy transfe	Reinke AW (2013)	1
SUMO2	0	RAD50	3	pull down	Ouyang J (2009)	1
SLX4	6	TOPBP1	5	affinity chromatography technology	Gritenaite D (2014)	1
MDM4	0	UBE2D1	0	pull down, pull down	Badciong JC (2002), Singh RK (2007)	2
XRCC5	5	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Um JH (2004), Um JH (2004)	2
HIST1H3A	3	VRK1	0	bioid	Lambert JP (2015)	1
NBN	1	ATF2	1	affinity chromatography technology, imaging technique	Bhoumik A (2005), Bhoumik A (2005)	2
NANOG	0	NBN	1	affinity chromatography technology	Oliviero G (2015)	1
RPA2	0	MDC1	8	affinity chromatography technology	Marechal A (2014)	1
FAM219A	1	RAD50	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TOPBP1	5	RPA1	0	imaging technique	Gong Z (2010)	1
HIST1H3A	3	MSH6	2	unspecified method, pull down	Sankaran SM (2016), Sankaran SM (2016)	2
MCPH1	4	RPA1	0	imaging technique	Rai R (2006)	1
FANCD2	3	MLH1	6	affinity chromatography technology	Williams SA (2011)	1
NCL	1	CD3EAP	3	pull down	Kobayashi J (2012)	1
XRCC5	5	PRKDC	12	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology	Jin S (1997), Matheos D (2002), Gell D (1999), Drouet J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Olsen BB (2012), Olsen BB (2012), Sand-Dejmek J (2011), Sartorius CA (2000), Sartorius CA (2000), Drouet J (2006), Drouet J (2006), Sibanda BL (2010), Wan C (2015), Hein MY (2015)	17
MRE11	3	BLM	2	biochemical	Wang Y (2000)	1
TERF2	2	H2AFX	1	two hybrid	Lee OH (2011)	1
MRE11	3	MSH2	4	biochemical	Wang Y (2000)	1
RNF8	2	XRCC5	5	affinity chromatography technology	Feng L (2012)	1
BRCA1	7	MSH2	4	two hybrid, pull down, biochemical, affinity chromatography technology, genetic interference	Wang Q (2001), Wang Q (2001), Wang Y (2000), Wada-Hiraike O (2005), Peng M (2014)	5
SUMO2	0	PRKDC	12	pull down	Ouyang J (2009)	1
TERF1	1	ATM	9	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down	Kishi S (2001), Kishi S (2001), Kishi S (2001), Takai H (2007), Karlseder J (2004)	5
CDC5L	2	RAD50	3	affinity chromatography technology	Lleres D (2010)	1
RPA2	0	MRE11	3	affinity chromatography technology	Marechal A (2014)	1
RGS20	2	RAD50	3	affinity chromatography technology	Huttlin EL (2017)	1
CHEK1	2	BLM	2	affinity chromatography technology, imaging technique, genetic interference	Sengupta S (2004), Sengupta S (2004), Srivas R (2016)	3
XRCC4	0	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Drouet J (2005), Havugimana PC (2012), Wang YG (2004)	3
H2AFX	1	BMI1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ginjala V (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011)	4
HIST1H3E	0	PRKDC	12	affinity chromatography technology, affinity chromatography technology, biochemical	Drane P (2010), Shuaib M (2010), Campos EI (2015)	3
MCM9	1	MLH1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Hutchins JR (2016), Traver S (2015), Traver S (2015), Traver S (2015), Traver S (2015)	5
SIRT1	3	NBN	1	affinity chromatography technology, pull down, enzymatic study	Yuan Z (2007), Yuan Z (2007), Yuan Z (2007)	3
CCNE1	1	MRE11	3	affinity chromatography technology	Stewart GS (2003)	1
BRCA1	7	MAPKAP1	0	affinity chromatography technology	Woods NT (2012)	1
CELA2B	1	MRE11	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PAXIP1	1	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Patel SR (2007), Cho YW (2007), Cho YW (2007)	3
MDC1	8	RECQL5	3	affinity chromatography technology	Woods NT (2012)	1
SUMO2	0	WRN	6	two hybrid	Hecker CM (2006)	1
EP300	36	MSH6	2	affinity chromatography technology	Jung SY (2005)	1
DDX1	6	RPA2	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Marechal A (2014)	2
TOPBP1	5	BRIP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gong Z (2010), Gong Z (2010), Gong Z (2010), Gong Z (2010), Sakasai R (2012), Sakasai R (2012), Guo M (2014)	7
BMI1	0	PRKDC	12	affinity chromatography technology	Facchino S (2010)	1
FANCD2	3	SLX4	6	affinity chromatography technology, imaging technique, affinity chromatography technology	Unno J (2014), Yamamoto KN (2011), Yamamoto KN (2011)	3
SNW1	0	MSH2	4	affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Lleres D (2010)	2
ATM	9	NAT2	0	two hybrid, affinity chromatography technology	Arroyo R (2015), Arroyo R (2015)	2
SUMO2	0	BLM	2	two hybrid	Hecker CM (2006)	1
KAT5	1	LZTS2	4	two hybrid	Rolland T (2014)	1
MDM4	0	NBN	1	affinity chromatography technology	Carrillo AM (2015)	1
BMP1	5	MRE11	3	affinity chromatography technology	Huttlin EL (2017)	1
CDC5L	2	ATR	6	affinity chromatography technology, affinity chromatography technology	Zhang N (2009), Zhang N (2009)	2
MCPH1	4	H2AFX	1	pull down, affinity chromatography technology	Shao Z (2011), Ge C (2015)	2
HIST1H3A	3	BARD1	4	bioid, affinity chromatography technology	Lambert JP (2015), Wu W (2015)	2
SNW1	0	ATRX	7	affinity chromatography technology	Lleres D (2010)	1
TLK1	5	NBN	1	enzymatic study	Krause DR (2003)	1
TERF2	2	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Zhu XD (2000), Zhu XD (2000), Li B (2008), Havugimana PC (2012)	4
MDM2	2	RBBP8	1	affinity chromatography technology	Okoro DR (2013)	1
MDC1	8	CDC5L	2	affinity chromatography technology	Woods NT (2012)	1
ATM	9	ATF2	1	enzymatic study, affinity chromatography technology	Bhoumik A (2005), Bhoumik A (2008)	2
CHEK1	2	TLK1	5	enzymatic study	Krause DR (2003)	1
ATM	9	FANCD2	3	pull down, affinity chromatography technology, two hybrid, enzymatic study	Taniguchi T (2002), Taniguchi T (2002), Reuter TY (2003), Taniguchi T (2002)	4
NBN	1	HIST3H3	0	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Cao LL (2016), Cao LL (2016), Cao LL (2016), Cao LL (2016)	4
NBN	1	CHEK1	2	genetic interference	Pichierri P (2004)	1
NBN	1	PRKDC	12	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
HDAC6	0	HIF1A	1	affinity chromatography technology	Qian DZ (2006)	1
ATM	9	BRCA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Gatei M (2000), Gatei M (2000), Kim ST (1999), Cortez D (1999), Cortez D (1999), Tibbetts RS (2000), Wang Y (2000), Mu JJ (2007), Tsai WB (2008), Gatei M (2000), Gatei M (2000), Gatei M (2000)	12
MTOR	14	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Geng Q (2017), Geng Q (2017), Geng Q (2017)	3
FANCD2	3	RAD18	3	affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, biochemical	Williams SA (2011), Williams SA (2011), Park HK (2010), Chen X (2016), Chen X (2016)	5
BMI1	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Cao Q (2014)	2
BRCA1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Woods NT (2012), Woods NT (2012)	3
DCLRE1C	3	ATM	9	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang X (2004), Zhang X (2004), Zhang X (2004)	3
BRCA1	7	TERF1	1	affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009)	2
BLM	2	TERF1	1	pull down	Lillard-Wetherell K (2004)	1
SKP2	2	BARD1	4	affinity chromatography technology	Lu Y (2012)	1
RAD18	3	UBE2A	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Xin H (2000), Xin H (2000), Tateishi S (2000), Tateishi S (2000), Markson G (2009), Inagaki A (2011), Watanabe K (2004), Masuda Y (2012), Masuda Y (2012), Masuda Y (2012), Watson NB (2008), Miyase S (2005), Barkley LR (2012), Unk I (2006), Kumar R (2014), Kumar R (2014), Zeman MK (2014), Masuda Y (2012), Hong JH (2015), Hein MY (2015), Hein MY (2015), Masuda Y (2015)	22
HDAC6	0	KAT5	1	affinity chromatography technology	Chen PB (2013)	1
PRKN	1	TUBG1	2	affinity chromatography technology, affinity chromatography technology	Hampe C (2006), Zhao J (2003)	2
POU5F1	0	FANCD2	3	affinity chromatography technology	Oliviero G (2015)	1
CBX8	3	EP300	36	affinity chromatography technology	Vandamme J (2011)	1
BRCA1	7	UBE2N	1	two hybrid, x-ray crystallography, pull down, two hybrid, pull down	Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Christensen DE (2007), David Y (2011)	5
POU5F1	0	TUBG1	2	affinity chromatography technology	Oliviero G (2015)	1
BRIP1	2	FANCD2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Clark DW (2015), Clark DW (2015), Chen X (2014), Chen X (2014), Chen X (2014)	5
SNW1	0	PRKDC	12	affinity chromatography technology	Lleres D (2010)	1
FANCD2	3	KAT5	1	two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Hejna J (2008), Hejna J (2008), Hejna J (2008), Hejna J (2008), Hejna J (2008)	5
BARD1	4	RAD50	3	biochemical, affinity chromatography technology	Greenberg RA (2006), Greenberg RA (2006)	2
CBX8	3	LIG3	6	affinity chromatography technology	Vandamme J (2011)	1
MSH6	2	XRCC5	5	affinity chromatography technology	Shahi A (2011)	1
MDM2	2	RNF8	2	two hybrid	Woodsmith J (2012)	1
RBBP8	1	MRE11	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lafranchi L (2014), Broderick R (2016), Liu H (2015), Ferretti LP (2016), Ferretti LP (2016)	5
TERF2IP	1	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), OConnor MS (2004), Liu D (2004), Havugimana PC (2012)	4
RPA3	2	NBN	1	affinity chromatography technology	Marechal A (2014)	1
PRKDC	12	CHEK1	2	unspecified method, pull down, genetic interference	Kim ST (1999), Goudelock DM (2003), Shen JP (2017)	3
RPA1	0	TERF2	2	affinity chromatography technology	Marechal A (2014)	1
RPA2	0	RFC1	1	affinity chromatography technology	Marechal A (2014)	1
RPA2	0	MSH2	4	affinity chromatography technology	Marechal A (2014)	1
TERF2IP	1	MRE11	3	affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), Liu D (2004), Havugimana PC (2012)	3
SNAI1	1	EP300	36	affinity chromatography technology	Hsu DS (2014)	1
NBN	1	CD3EAP	3	affinity chromatography technology	Yanagihara H (2011)	1
RPA1	0	CDC5L	2	affinity chromatography technology, pull down, affinity chromatography technology	Marechal A (2014), Marechal A (2014), Lleres D (2010)	3
EP300	36	NANOG	0	affinity chromatography technology	Xie X (2014)	1
BRCA1	7	MLH1	6	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cannavo E (2007), Suhasini AN (2011), Hill SJ (2014)	4
CELA2B	1	RAD50	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RECQL5	3	PRKDC	12	affinity chromatography technology	Zheng L (2009)	1
MSH2	4	CHEK1	2	affinity chromatography technology	Adamson AW (2005)	1
SNW1	0	RAD18	3	affinity chromatography technology	Lleres D (2010)	1
RPA3	2	DDX1	6	affinity chromatography technology	Marechal A (2014)	1
RPA2	0	TERF2	2	affinity chromatography technology	Marechal A (2014)	1
EP300	36	SNW1	0	pull down	Leong GM (2004)	1
NBN	1	RAD50	3	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Desai-Mehta A (2001), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Greenberg RA (2006), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015)	17
UBE2A	0	RPA2	0	biochemical	Wan C (2015)	1
PAXIP1	1	CBX8	3	two hybrid	Woods NT (2012)	1
RNF8	2	H2AFX	1	enzymatic study, enzymatic study, imaging technique	Mattiroli F (2012), Yu M (2016), Liang L (2017)	3
NBN	1	H2AFX	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kobayashi J (2002), Kobayashi J (2002), Park JH (2006), Cheng WH (2005), Lukas C (2004), Kobayashi J (2002), Kobayashi J (2002), Pan MR (2011), Kobayashi J (2012)	9
BRIP1	2	BRCA1	7	affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, unspecified method, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Botuyan MV (2004), Botuyan MV (2004), Botuyan MV (2004), Joo WS (2002), Yu X (2003), Yu X (2003), Rodriguez M (2003), Rodriguez M (2003), Clapperton JA (2004), Clapperton JA (2004), Yu X (2003), Kim H (2007), Sobhian B (2007), Suhasini AN (2011), Xie J (2010), Peng M (2007), Peng M (2007), Gupta R (2007), Nelson AC (2010), Nelson AC (2010), Nomine Y (2008), Dohrn L (2012), Drikos I (2009), Tischkowitz M (2008), Campbell SJ (2010), Hill SJ (2014), Wu W (2016), Suhasini AN (2013), Sakasai R (2012), Guo M (2014), Ertych N (2016)	31
BMI1	0	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2009), Maertens GN (2009), Maertens GN (2010), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	11
BARD1	4	NBN	1	biochemical, affinity chromatography technology	Greenberg RA (2006), Greenberg RA (2006)	2
CDC5L	2	MRE11	3	affinity chromatography technology	Lleres D (2010)	1
HDAC6	0	XRCC5	5	affinity chromatography technology	New M (2013)	1
BLM	2	RFC1	1	biochemical	Wang Y (2000)	1
MSH2	4	BLM	2	biochemical, affinity chromatography technology	Wang Y (2000), Yang Q (2004)	2
MLH1	6	BLM	2	biochemical, pull down, two hybrid, far western blotting, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, two hybrid, unspecified method, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Langland G (2001), Langland G (2001), Langland G (2001), Langland G (2001), Freire R (2001), Pedrazzi G (2001), Pedrazzi G (2001), Pedrazzi G (2001), Dherin C (2009), Dherin C (2009), Meetei AR (2003), Meetei AR (2003)	13
HIST1H3A	3	HDAC6	0	pull down	Li X (2014)	1
NBN	1	HSPA4	3	affinity chromatography technology	Falck J (2005)	1
CHEK1	2	FANCD2	3	enzymatic study, genetic interference	Zhi G (2009), Pichierri P (2004)	2
NBN	1	BLM	2	biochemical	Wang Y (2000)	1
SIRT1	3	SNW1	0	two hybrid, pull down, affinity chromatography technology	Kang MR (2010), Kang MR (2010), Kang MR (2010)	3
EP300	36	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liu B (2009), Brackertz M (2006), Faiola F (2005), Daujat S (2002), Kalkhoven E (2002), Seo SB (2002), Kim JH (2005), Bordoli L (2001), Kim MY (2001), Kutney SN (2004), Wang F (2010), Loven MA (2004), Kiernan RE (1999), Wong K (2005), Ogryzko VV (1996), Yamaguchi Y (2004), Furumatsu T (2005), An W (2002), Delvecchio M (2013), Delvecchio M (2013), Tropberger P (2013), Das C (2009), Shimura M (2011), Ji A (2003), Fu M (2005), Suganuma T (2002), Tang Z (2013), Kim JH (2006), Lopes da Rosa J (2013), Li X (2014), Wang YL (2008), Du C (2017), Yi P (2017), Wan W (2017)	34
BRIP1	2	RPA1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down	Gong Z (2010), Gupta R (2007), Gupta R (2007), Gupta R (2007), Gupta R (2007)	5
H2AFX	1	KAT5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Heo K (2008), Heo K (2008), Heo K (2008), Lee HS (2010)	4
ATM	9	WRN	6	unspecified method	Kim ST (1999)	1
ATM	9	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun Y (2009), Sun Y (2005), Sun Y (2005), Dittmann K (2011)	4
NBN	1	IPO5	0	affinity chromatography technology	Falck J (2005)	1
SNW1	0	DDX1	6	affinity chromatography technology	Lleres D (2010)	1
RAD50	3	MCM9	1	affinity chromatography technology, affinity chromatography technology	Lee KY (2015), Lee KY (2015)	2
KAT5	1	RAD50	3	affinity chromatography technology	Chailleux C (2010)	1
MDC1	8	WRN	6	unspecified method	Rodriguez M (2003)	1
ATR	6	DCLRE1C	3	enzymatic study	Zhang X (2004)	1
PAXIP1	1	MDC1	8	affinity chromatography technology	Woods NT (2012)	1
RPA1	0	MDC1	8	affinity chromatography technology	Marechal A (2014)	1
RPA3	2	PRKDC	12	affinity chromatography technology	Marechal A (2014)	1
KAT5	1	NBN	1	affinity chromatography technology	Chailleux C (2010)	1
DCLRE1C	3	MRE11	3	affinity chromatography technology	Zhang X (2004)	1
BARD1	4	MRE11	3	affinity chromatography technology	Greenberg RA (2006)	1
TOPBP1	5	MDC1	8	biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Wang J (2011), Wang J (2011), Wang J (2011), Wang J (2013)	4
MSH6	2	MLH1	6	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Matton N (2000), Matton N (2000), Plotz G (2003), Plotz G (2003)	5
RPA1	0	NCL	1	affinity chromatography technology	Marechal A (2014)	1
HIST1H3E	0	NBN	1	affinity chromatography technology	Campos EI (2015)	1
NBN	1	VRK1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Monsalve DM (2016), Monsalve DM (2016), Monsalve DM (2016)	3
PAXIP1	1	EP300	36	pull down	Hoffmeister A (2002)	1
HIST1H3E	0	RAD50	3	affinity chromatography technology	Campos EI (2015)	1
OFD1	3	MRE11	3	affinity chromatography technology	Gupta GD (2015)	1
RAD18	3	NBN	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Yanagihara H (2011), Yanagihara H (2011), Yanagihara H (2011), Yanagihara H (2011)	4
MDM2	2	HSPA4	3	affinity chromatography technology	Lu TL (2010)	1
BRCA1	7	RBBP8	1	unspecified method, two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Rodriguez M (2003), Li S (1999), Li S (1999), Li S (1999), Wong AK (1998), Wong AK (1998), Li S (2000), Wu-Baer F (2001), Yu X (1998), Yu X (1998), Yu X (2000), Yu X (2000), Yu X (2000), Kim H (2007), Yu X (2006), Yu X (2006), Wu-Baer F (2010), Volcic M (2012), Wang B (2007), Wang B (2007), Furuta S (2006), Furuta S (2006), Drikos I (2009), Tischkowitz M (2008), Li S (2000), Wu-Baer F (2001), Chen L (2008), Sevcik J (2013), Johnson N (2013), Hill SJ (2014), Cruz-Garcia A (2014), Hu Y (2014), Parameswaran B (2015), Liu H (2015), Renaud E (2016)	35
XRCC5	5	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wei L (2008), Wei L (2008), Jiang G (2013), Jiang G (2013), Jiang G (2013), Ertych N (2016)	6
DCLRE1C	3	BRCA1	7	affinity chromatography technology	Zhang X (2004)	1
UBE2N	1	RNF8	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, fluorescent resonance energy transfe, pull down, two hybrid	Markson G (2009), Bekker-Jensen S (2010), Lok GT (2011), Lok GT (2011), Campbell SJ (2012), Plans V (2006), Plans V (2006), Huen MS (2008), Zhang X (2013), Guerra-Rebollo M (2012), Zhao H (2014), Hodge CD (2015), Ho YK (2015), Weber E (2017), Weber E (2017), Schimmack G (2017)	16
MED4	2	OFD1	3	bioid	Lambert JP (2015)	1
NCL	1	CDC5L	2	affinity chromatography technology	Salvetti A (2016)	1
NBN	1	RBBP8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Chen L (2008), Chen L (2008), Liu H (2015), Liu H (2015), Liu H (2015), Ferretti LP (2016), Ferretti LP (2016)	7
XRCC5	5	ATM	9	pull down	Falck J (2005)	1
RPA3	2	ATRIP	1	affinity chromatography technology, pull down	Marechal A (2014), Tomida J (2013)	2
RPA1	0	LIG3	6	affinity chromatography technology, affinity chromatography technology	Marechal A (2014), Elia AE (2015)	2
BMI1	0	NBN	1	affinity chromatography technology	Wei F (2015)	1
ATM	9	HIF1A	1	enzymatic study	Cam H (2010)	1
XRCC5	5	RFC1	1	affinity chromatography technology, biochemical	Matheos D (2002), Wan C (2015)	2
SNW1	0	MLH1	6	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	TUBG1	2	imaging technique, affinity chromatography technology, pull down, biochemical, imaging technique, affinity chromatography technology, enzymatic study, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down	Hsu LC (2001), Hsu LC (2001), Hsu LC (2001), Hsu LC (1998), Hsu LC (1998), Hsu LC (1998), Starita LM (2004), Brodie KM (2012), Tarapore P (2012), Tarapore P (2012), Tarapore P (2012), Matsuzawa A (2014)	12
WRN	6	H2AFX	1	affinity chromatography technology, pull down	Cheng WH (2005), Cheng WH (2005)	2
BRCA1	7	CCNE1	1	affinity chromatography technology	Matsuoka S (2007)	1
BACH1	3	MLH1	6	affinity chromatography technology	Greenberg RA (2006)	1
CDC5L	2	UBE2D1	0	affinity chromatography technology	Lleres D (2010)	1
ATR	6	FANCD2	3	enzymatic study, imaging technique, enzymatic study	Ho GP (2006), Pichierri P (2004), Shigechi T (2012)	3
KAT5	1	MRE11	3	affinity chromatography technology	Chailleux C (2010)	1
NBN	1	TERF1	1	two hybrid	Wu G (2000)	1
EYA2	2	NBN	1	bioid	St-Denis N (2016)	1
NCL	1	MSH6	2	affinity chromatography technology, affinity chromatography technology	Salvetti A (2016), Salvetti A (2016)	2
ATRIP	1	MSH2	4	affinity chromatography technology, affinity chromatography technology	Wang Y (2003), Wang Y (2003)	2
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
XRCC5	5	MSH2	4	biochemical	Kristensen AR (2012)	1
MRE11	3	RAD50	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Chiba N (2001), Chiba N (2001), Dolganov GM (1996), Dolganov GM (1996), Trujillo KM (1998), Goedecke W (1999), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Cho YW (2007), Greenberg RA (2006), Alt JR (2005), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Wijnhoven P (2015), Boldt K (2016), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015), Nicholson J (2017)	25
PAXIP1	1	HIST1H3A	3	enzymatic study	Patel SR (2007)	1
NBN	1	LIG3	6	affinity chromatography technology	Falck J (2005)	1
UBE2A	0	NCL	1	affinity chromatography technology	An H (2017)	1
BRCA1	7	ATRIP	1	affinity chromatography technology, pull down, x-ray crystallography	Venere M (2007), Liu X (2013), Liu X (2013)	3
PRKDC	12	HIST1H3A	3	imaging technique	Olsen BB (2012)	1
SUMO2	0	XRCC5	5	pull down	Ouyang J (2009)	1
BARD1	4	UBE2N	1	pull down	David Y (2011)	1
BMI1	0	HIST1H3A	3	affinity chromatography technology	Abdouh M (2016)	1
RPA3	2	MDC1	8	affinity chromatography technology	Marechal A (2014)	1
SNW1	0	CHEK1	2	affinity chromatography technology	Lleres D (2010)	1
NBN	1	XRCC4	0	two hybrid	Matsuzaki K (2008)	1
TERF1	1	TERF2IP	1	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Huttlin EL (2015), Hein MY (2015)	6
PHRF1	7	HIST3H3	0	affinity chromatography technology, unspecified method	Chang CF (2015), Chang CF (2015)	2
HIST1H3A	3	RECQL5	3	bioid	Lambert JP (2015)	1
BLM	2	H2AFX	1	affinity chromatography technology, imaging technique	Sengupta S (2004), Sengupta S (2004)	2
DPPA4	0	MDC1	8	affinity chromatography technology	Oliviero G (2015)	1
ATF2	1	RAD18	3	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	RAD50	3	affinity chromatography technology, pull down	Jung SY (2005), Karmakar S (2010)	2
SNW1	0	ATM	9	affinity chromatography technology	Lleres D (2010)	1
UBE2D1	0	MDM2	2	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Singh RK (2007), Poyurovsky MV (2007), Li M (2003), Yogosawa S (2003), Honda R (1997), Sun XX (2011), Singh RK (2007), Taira N (2010), Fu X (2010), Wang KS (2011), Wang X (2004), Sehat B (2008), Wawrzynow B (2007), Burch L (2004), Frazier DP (2012), Huart AS (2012), Pettersson S (2009), Gama V (2009), Demma M (2010), Chymkowitch P (2011), Yan C (2010), Yang Y (2013), Ranaweera RS (2013), Siepe D (2009), Shi D (2009), Uchiki T (2009), Grossman SR (2003), Xirodimas DP (2004), Saville MK (2004), Liu T (2015), Batuello CN (2015), Fraser JA (2015), Yamauchi T (2014), Liu D (2016), McClurg UL (2016), Landre V (2017)	36
RPA2	0	WRN	6	affinity chromatography technology	Marechal A (2014)	1
ATRX	7	RAD50	3	affinity chromatography technology	Leung JW (2013)	1
NBN	1	MSH2	4	biochemical	Wang Y (2000)	1
RPA1	0	MED4	2	affinity chromatography technology	Marechal A (2014)	1
MDM2	2	RAD50	3	affinity chromatography technology, affinity chromatography technology	Alt JR (2005), Alt JR (2005)	2
BARD1	4	HSPA4	3	affinity chromatography technology	Tembe V (2015)	1
CHEK1	2	WRN	6	genetic interference	Srivas R (2016)	1
NBN	1	MSH6	2	biochemical	Wang Y (2000)	1
HIF1A	1	NBN	1	affinity chromatography technology, affinity chromatography technology, pull down	Kuo YC (2015), Kuo YC (2015), Kuo YC (2015)	3
RAD50	3	MSH6	2	biochemical	Wang Y (2000)	1
MED4	2	NBN	1	bioid	Lambert JP (2015)	1
LZTS2	4	NBN	1	affinity chromatography technology	Huttlin EL (2017)	1
CDC5L	2	RAD18	3	affinity chromatography technology	Lleres D (2010)	1
RPA3	2	CDC5L	2	affinity chromatography technology, pull down	Marechal A (2014), Marechal A (2014)	2
H2AFX	1	NCL	1	pull down, pull down	Kobayashi J (2012), Kobayashi J (2012)	2
ATF2	1	KAT5	1	affinity chromatography technology	Bhoumik A (2008)	1
MCM9	1	NBN	1	affinity chromatography technology	Lee KY (2015)	1
RECQL5	3	NCL	1	affinity chromatography technology	Zheng L (2009)	1
BLM	2	RPA3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meetei AR (2003), Meetei AR (2003), Marechal A (2014)	3
MRE11	3	HIST3H3	0	affinity chromatography technology, affinity chromatography technology	Cao LL (2016), Cao LL (2016)	2
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
MAPKAP1	0	MTOR	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Pearce LR (2007), Oh WJ (2010), Yang Q (2006), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Hong F (2008), Facchinetti V (2008), Facchinetti V (2008), Glidden EJ (2012), Vander Haar E (2007)	17
BRCA1	7	MSH6	2	two hybrid, pull down, biochemical, affinity chromatography technology	Wang Q (2001), Wang Q (2001), Wang Y (2000), Hill SJ (2014)	4
OFD1	3	HSPA4	3	bioid	Gupta GD (2015)	1
H2AFX	1	LIG3	6	affinity chromatography technology	Huttlin EL (2017)	1
RECQL5	3	NBN	1	affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009)	3
SNW1	0	TUBG1	2	affinity chromatography technology	Lleres D (2010)	1
HSPA4	3	PRKN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Moore DJ (2008), Hampe C (2006), Tsai YC (2003), Morishima Y (2008), Kalia SK (2004), Kalia SK (2004), Imai Y (2003), Imai Y (2003)	8
RPA3	2	ATR	6	affinity chromatography technology	Marechal A (2014)	1
BMI1	0	KAT5	1	two hybrid	Stelzl U (2005)	1
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
NBN	1	UBE2B	3	affinity chromatography technology	Yanagihara H (2011)	1
ATRIP	1	PRKDC	12	pull down	Falck J (2005)	1
SUMO2	0	MDC1	8	pull down	Ouyang J (2009)	1
SUMO2	0	MSH2	4	pull down, pull down	Ouyang J (2009), Ouyang J (2015)	2
TERF2	2	WRN	6	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Li B (2008)	6
ATRX	7	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung JW (2013), Leung JW (2013), Huh MS (2016)	3
MTOR	14	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007)	59
CELA2B	1	NBN	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	IPO5	0	affinity chromatography technology	Ertych N (2016)	1
RPA3	2	RFC1	1	affinity chromatography technology	Marechal A (2014)	1
RECQL5	3	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009), Zheng L (2009)	4
TERF1	1	XRCC5	5	affinity chromatography technology	Giannone RJ (2010)	1
MDM2	2	HIF1A	1	pull down, affinity chromatography technology, enzymatic study, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Chen D (2003), Chen D (2003), Ravi R (2000), Lee YM (2009), Lee YM (2009), Lee YM (2009), Maroni P (2014), Amelio I (2015), Yoo YG (2004), LaRusch GA (2007), LaRusch GA (2007), Nieminen AL (2005)	12
H2AFX	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Sand-Dejmek J (2011)	3
SKP2	2	MRE11	3	affinity chromatography technology	Wu J (2012)	1
CDC5L	2	UBE2N	1	affinity chromatography technology	Lleres D (2010)	1
RPA2	0	ATRIP	1	affinity chromatography technology, pull down	Marechal A (2014), Tomida J (2013)	2
RPA3	2	RPA1	0	biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015)	8
XRCC5	5	ATR	6	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
CDC5L	2	MSH2	4	affinity chromatography technology	Lleres D (2010)	1
XRCC5	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Zhang Z (2017), Zhang Z (2017)	2
ATRIP	1	ATM	9	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
BARD1	4	TOPBP1	5	biochemical, affinity chromatography technology	Greenberg RA (2006), Greenberg RA (2006)	2
HDAC6	0	MLH1	6	affinity chromatography technology, affinity chromatography technology	Zhang M (2014), Zhang M (2014)	2
KAT5	1	PRKDC	12	affinity chromatography technology, affinity chromatography technology	Jiang X (2006), Jiang X (2006)	2
NBN	1	MAPKAP1	0	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
CHEK1	2	MTOR	14	genetic interference, genetic interference, genetic interference	Shen JP (2017), Srivas R (2016), Srivas R (2016)	3
EYA2	2	LZTS2	4	bioid	St-Denis N (2016)	1
BACH1	3	MRE11	3	affinity chromatography technology	Greenberg RA (2006)	1
WRN	6	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng WH (2005), Kobayashi J (2010), Kobayashi J (2010)	3
MDM2	2	HIST3H3	0	pull down, enzymatic study, affinity chromatography technology	Chen L (2010), Chen L (2010), Chen L (2010)	3
HIST3H3	0	NCL	1	unspecified method	Vermeulen M (2010)	1
TERF1	1	EP300	36	affinity chromatography technology	Her YR (2013)	1
NBN	1	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
RGS20	2	MRE11	3	affinity chromatography technology	Huttlin EL (2017)	1
MLH1	6	PRKDC	12	affinity chromatography technology	Cannavo E (2007)	1
NBN	1	RFC1	1	biochemical	Wang Y (2000)	1
SNW1	0	RPA1	0	affinity chromatography technology	Lleres D (2010)	1
NCL	1	NBN	1	pull down	Kobayashi J (2012)	1
PRKDC	12	H2AFX	1	enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Park EJ (2003), Mischo HE (2005), Heo K (2008), Heo K (2008), Li A (2010), Kim K (2012)	6
CDC5L	2	MSH6	2	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	MTOR	14	affinity chromatography technology	Woods NT (2012)	1
WRN	6	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Zhang N (2005), Zhang N (2005)	2
RAD50	3	RBBP8	1	affinity chromatography technology	Greenberg RA (2006)	1
BAP1	4	IPO5	0	affinity chromatography technology	Sowa ME (2009)	1
MDC1	8	BARD1	4	affinity chromatography technology	Lou Z (2003)	1
BRCA1	7	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Kang HJ (2006), Kang HJ (2006)	2
TERF2	2	HSPA4	3	affinity chromatography technology	Giannone RJ (2010)	1
MDM4	0	RAD50	3	affinity chromatography technology	Carrillo AM (2015)	1
SLX4	6	MSH6	2	affinity chromatography technology	Ghosal G (2012)	1
ATM	9	MDM2	2	enzymatic study, enzymatic study	Wang Z (2012), Luo H (2016)	2
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
BARD1	4	KAT5	1	two hybrid	Goehler H (2004)	1
RICTOR	4	HSPA4	3	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Pearce LR (2007), Martin J (2008), Martin J (2008), Martin J (2008)	4
RPA3	2	MSH2	4	affinity chromatography technology	Marechal A (2014)	1
PRKN	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Staropoli JF (2003), Veeriah S (2010), Veeriah S (2010), Gong Y (2014), Gong Y (2014)	5
SUMO2	0	SLX4	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ouyang J (2009), Ouyang J (2015), Ouyang J (2015), Ouyang J (2015), Guervilly JH (2015), Guervilly JH (2015)	6
UBE2D1	0	HIF1A	1	enzymatic study	Miller F (2005)	1
MSH6	2	ATM	9	biochemical	Wang Y (2000)	1
PRKDC	12	DCLRE1C	3	pull down, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Ma Y (2002), Ma Y (2002), Ma Y (2002), Zhang X (2004), Ma Y (2005), Drouet J (2006), Drouet J (2006)	7
TERF2	2	NBN	1	affinity chromatography technology, affinity chromatography technology, biochemical	Zhu XD (2000), Zhu XD (2000), Havugimana PC (2012)	3
SNW1	0	LZTS2	4	two hybrid	Rolland T (2014)	1
RAD50	3	HIST3H3	0	affinity chromatography technology, affinity chromatography technology	Cao LL (2016), Cao LL (2016)	2
MLH1	6	RFC1	1	biochemical	Wang Y (2000)	1
ATF2	1	MLH1	6	two hybrid	Wang J (2011)	1
RPA1	0	NBN	1	affinity chromatography technology	Marechal A (2014)	1
SKP2	2	ATM	9	affinity chromatography technology	Wu J (2012)	1
BARD1	4	RBBP8	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu X (2000), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Wu-Baer F (2010), Coleman KA (2011), Hu Y (2014)	7
FANCD2	3	RPA1	0	affinity chromatography technology	Unno J (2014)	1
EP300	36	NBN	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Jung SY (2005), Jang ER (2011), Jang ER (2011)	3
ATM	9	RPA2	0	enzymatic study	Chan DW (2000)	1
TERF2	2	TERF1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Giannone RJ (2010), Ye JZ (2004), Ye JZ (2004)	3
MDC1	8	FANCD2	3	affinity chromatography technology	Stewart GS (2003)	1
RAD50	3	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Acharya S (2014), Acharya S (2014)	3
DDX1	6	MRE11	3	affinity chromatography technology, biochemical	Li L (2008), Kristensen AR (2012)	2
SLX4	6	TERF2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, imaging technique, x-ray crystallography, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Wilson JS (2013), Wilson JS (2013), Wilson JS (2013), Wan B (2013), Wan B (2013), Wan B (2013), Wan B (2013), Wan B (2013), Ouyang J (2015)	11
ATRIP	1	NBN	1	affinity chromatography technology	Falck J (2005)	1
RAD18	3	UBE2B	3	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, biochemical, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Xin H (2000), Xin H (2000), Tateishi S (2000), Tateishi S (2000), Markson G (2009), Hibbert RG (2011), Inagaki A (2011), Watanabe K (2004), Huang A (2011), Huang A (2011), Huang A (2011), Notenboom V (2007), Notenboom V (2007), Song IY (2010), Tomida J (2008), Masuda Y (2010), Han J (2014), Hong JH (2015), Huttlin EL (2017), Foglizzo M (2016)	20
ATR	6	ATM	9	unspecified method, enzymatic study	Kim ST (1999), Stiff T (2006)	2
ATR	6	CHEK1	2	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, genetic interference	Kim ST (1999), Sun TP (2009), Zhao H (2001), Rocha S (2005), Choi JH (2007), Ha K (2011), Srivas R (2016)	7
RPA1	0	DDX1	6	affinity chromatography technology	Marechal A (2014)	1
PRKDC	12	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Gong Z (2011), Marechal A (2014)	3
ATM	9	H2AFX	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tsai WB (2008), Tsai WB (2008), Dittmann K (2011), Pan MR (2011), Kim K (2012), Rezaeian AH (2017)	6
MED4	2	XRCC4	0	affinity chromatography technology	Lambert JP (2015)	1
HIST3H3	0	BMI1	0	unspecified method	Vermeulen M (2010)	1
ATM	9	RFC1	1	biochemical	Wang Y (2000)	1
ATM	9	BMI1	0	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Pan MR (2011)	2
RNF8	2	SUMO2	0	two hybrid, pull down, affinity chromatography technology, imaging technique	Liang L (2017), Liang L (2017), Liang L (2017), Liang L (2017)	4
HIST1H3A	3	NBN	1	affinity chromatography technology	Fnu S (2011)	1
ATR	6	H2AFX	1	imaging technique, enzymatic study	Ray A (2009), Kim K (2012)	2
ATM	9	NBN	1	unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Cariveau MJ (2007), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Wu J (2012), Wei F (2015)	12
SNW1	0	NBN	1	affinity chromatography technology	Lleres D (2010)	1
SLX4	6	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Ghosal G (2012)	3
RPA3	2	MED4	2	affinity chromatography technology	Marechal A (2014)	1
BACH1	3	BARD1	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Kumaraswamy E (2007), Kumaraswamy E (2007), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Hu Y (2014)	7
MRE11	3	MSH6	2	biochemical	Wang Y (2000)	1
SLX4	6	MRE11	3	affinity chromatography technology	Ouyang J (2015)	1
BRCA1	7	HSPA4	3	affinity chromatography technology	Ertych N (2016)	1
OFD1	3	RAD50	3	affinity chromatography technology	Gupta GD (2015)	1
HIST1H3A	3	RFC1	1	bioid	Lambert JP (2015)	1
NBN	1	MLH1	6	biochemical	Wang Y (2000)	1
CDC5L	2	IPO5	0	affinity chromatography technology	Lleres D (2010)	1
XRCC5	5	HSPA4	3	biochemical	Kristensen AR (2012)	1
SNW1	0	BLM	2	affinity chromatography technology	Lleres D (2010)	1
MDM4	0	MRE11	3	affinity chromatography technology	Carrillo AM (2015)	1
SUMO2	0	BRCA1	7	affinity chromatography technology	Hu X (2012)	1
RPA3	2	LIG3	6	affinity chromatography technology	Marechal A (2014)	1
MCM9	1	MRE11	3	affinity chromatography technology	Lee KY (2015)	1
BMI1	0	TERF2	2	affinity chromatography technology	Cao Q (2014)	1
TUBG1	2	RICTOR	4	affinity chromatography technology	Hein MY (2015)	1
MSH6	2	PRKDC	12	affinity chromatography technology	Shahi A (2011)	1
CHEK1	2	MDM4	0	enzymatic study, enzymatic study	Jin Y (2006), Chen L (2005)	2
BRCA1	7	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down, two hybrid, x-ray crystallography, pull down, two hybrid, pull down, pull down, pull down, pull down	Mallery DL (2002), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Wu-Baer F (2003), Hashizume R (2001), Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Morris JR (2006), Vandenberg CJ (2003), Morris JR (2006), Nhukeaw T (2014), Thakar A (2010)	14
BMI1	0	CASC3	0	affinity chromatography technology	Cao Q (2014)	1
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
HDAC6	0	DDX1	6	affinity chromatography technology	New M (2013)	1
MCPH1	4	ATR	6	imaging technique	Rai R (2006)	1
DCLRE1C	3	RAD50	3	affinity chromatography technology	Zhang X (2004)	1
PRKN	1	UBE2A	0	pull down	Kazlauskaite A (2014)	1
RAD50	3	ATM	9	biochemical	Wang Y (2000)	1
EP300	36	HIF1A	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Lando D (2002), Freedman SJ (2002), Lewis MD (2004), Matt T (2004), Sang N (2002), Luo W (2010), Freedman SJ (2003), Bodily JM (2011), Lee YM (2009), Lee YM (2009), Lee YM (2009), Kung AL (2004), Kung AL (2004), Kung AL (2004), Land SC (2007), Zhang Y (2010), Zhang Y (2010), Fath DM (2006), Fath DM (2006), Lee SJ (2013), Wang D (2014), Kaluz S (2006), Kaluz S (2006), Kaluz S (2006), Shin DH (2008), Shin DH (2008), Wang Y (2012), Huang C (2009), Hewitson KS (2002), Cook KM (2009), Cook KM (2009), Hubbi ME (2012), Kim SY (2014), Sang N (2003), Sang N (2003), Sang N (2003), Yasinska IM (2003), Na YR (2013), Na YR (2013), Mendonca DB (2011), Arany Z (1996), Arany Z (1996), Chen R (2012), Li SH (2008), Galbraith MD (2013), Chen Z (2014), Li Q (2012), Geng H (2012), Geng H (2012), Kato H (2004), Lim JH (2010), Kyle HF (2015), Kyle HF (2015), Rath S (2016), Kimura M (2008), Dubey R (2013)	56
SUMO2	0	MRE11	3	pull down	Ouyang J (2009)	1
MDC1	8	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Xu X (2003), Xu X (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Stewart GS (2003), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	10
MSH6	2	ATR	6	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
CBX8	3	NBN	1	affinity chromatography technology	Vandamme J (2011)	1
UBE2D1	0	HDAC6	0	enzymatic study	Hoeller D (2007)	1
TERF2	2	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), Zhu XD (2000), Zhu XD (2000), Li B (2008), Havugimana PC (2012)	5
TOPBP1	5	CHEK1	2	enzymatic study	Choi JH (2007)	1
ATM	9	RPA1	0	enzymatic study	Chan DW (2000)	1
ATR	6	HSPA4	3	affinity chromatography technology	Ha K (2011)	1
ATRX	7	PRKDC	12	affinity chromatography technology	Leung JW (2013)	1
RAD50	3	MSH2	4	biochemical	Wang Y (2000)	1
NBN	1	MTOR	14	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
EP300	36	HIST3H3	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Seo SB (2001), Ott M (1999), Thomas MC (2005), Sabari BR (2015), Sabari BR (2015), Yi P (2015)	6
BACH1	3	NBN	1	affinity chromatography technology	Greenberg RA (2006)	1
UBE2A	0	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lyakhovich A (2003), Chen S (2012), Chen S (2012)	3
MSH2	4	RFC1	1	biochemical	Wang Y (2000)	1
MDM2	2	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alt JR (2005), Alt JR (2005), Bouska A (2008)	3
RPA3	2	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
ATRX	7	HIST1H3A	3	pull down	Dhayalan A (2011)	1
RNF8	2	UBE2D1	0	pull down, pull down	Ito K (2001), Feng L (2012)	2
TOPBP1	5	NBN	1	affinity chromatography technology, affinity chromatography technology	Morishima K (2007), Morishima K (2007)	2
RPA3	2	MRE11	3	affinity chromatography technology	Marechal A (2014)	1
BARD1	4	MSH6	2	pull down, biochemical	Wang Q (2001), Greenberg RA (2006)	2
NBN	1	NAT2	0	two hybrid	Arroyo R (2015)	1
NANOG	0	PAXIP1	1	affinity chromatography technology	Oliviero G (2015)	1
MCPH1	4	KAT5	1	two hybrid	Liu X (2017)	1
MSH6	2	RFC1	1	biochemical	Wang Y (2000)	1
BMI1	0	EP300	36	affinity chromatography technology	Cao Q (2014)	1
LIG3	6	XRCC5	5	affinity chromatography technology, pull down	Leppard JB (2003), Leppard JB (2003)	2
SNW1	0	ATR	6	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	RECQL5	3	affinity chromatography technology	Woods NT (2012)	1
EP300	36	SUMO2	0	pull down, enzymatic study	Ullmann R (2012), Ullmann R (2012)	2
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
UBE2B	3	MDM2	2	affinity chromatography technology	Chen S (2012)	1
FANCD2	3	MSH2	4	affinity chromatography technology, genetic interference	Williams SA (2011), Peng M (2014)	2
KAT5	1	BRCA1	7	two hybrid	Hill SJ (2014)	1
PAXIP1	1	MRE11	3	affinity chromatography technology, affinity chromatography technology	Cho YW (2007), Cho YW (2007)	2
HIST3H3	0	CBX8	3	unspecified method, x-ray crystallography, unspecified method	Kaustov L (2011), Kaustov L (2011), Vermeulen M (2010)	3
FAM219A	1	NBN	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VRK1	0	HIST3H3	0	affinity chromatography technology	Cantarero L (2015)	1
POU5F1	0	PRKDC	12	affinity chromatography technology	Oliviero G (2015)	1
CBX8	3	LZTS2	4	two hybrid	Rolland T (2014)	1
RPA1	0	RAD50	3	affinity chromatography technology	Marechal A (2014)	1
UBE2A	0	RPA3	2	biochemical	Wan C (2015)	1
SUMO2	0	IPO5	0	pull down	Ouyang J (2009)	1
CDC5L	2	NBN	1	affinity chromatography technology	Lleres D (2010)	1
RPA2	0	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
ATM	9	BLM	2	biochemical, pull down, affinity chromatography technology	Wang Y (2000), Beamish H (2002), Beamish H (2002)	3
SLX4	6	NBN	1	affinity chromatography technology	Ouyang J (2015)	1
HDAC6	0	HSPA4	3	affinity chromatography technology	New M (2013)	1
TERF1	1	PRKDC	12	affinity chromatography technology	Takai H (2007)	1
PAXIP1	1	H2AFX	1	x-ray crystallography, unspecified method	Yan W (2011), Yan W (2011)	2
EP300	36	ATF2	1	biochemical	Duyndam MC (1999)	1
EP300	36	MDM2	2	pull down, affinity chromatography technology, biochemical, pull down, pull down, enzymatic study, affinity chromatography technology, biochemical, enzymatic study	Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Matt T (2004), Wang X (2004), Gillotin S (2010), Kobet E (2000), Nihira NT (2017)	9
HIST1H3E	0	MRE11	3	affinity chromatography technology	Campos EI (2015)	1
CHEK1	2	MCPH1	4	pull down	Alderton GK (2006)	1
BLM	2	RPA2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meetei AR (2003), Meetei AR (2003), Marechal A (2014)	3
H2AFX	1	HIF1A	1	affinity chromatography technology, imaging technique	Rezaeian AH (2017), Rezaeian AH (2017)	2
TERF1	1	HSPA4	3	affinity chromatography technology	Giannone RJ (2010)	1
ATRIP	1	RPA1	0	imaging technique, pull down, affinity chromatography technology, pull down, pull down	Zou L (2003), Liu Y (2011), Marechal A (2014), Tomida J (2013), Shigechi T (2012)	5
TERF2	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), Giannone RJ (2010)	2
ATR	6	BRCA1	7	pull down, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tibbetts RS (2000), Kim ST (1999), Mu JJ (2007), Chen J (2000), Chen J (2000), Tibbetts RS (2000), Gatei M (2001), Gatei M (2001), Gatei M (2001), Tian F (2013)	10
BRCA1	7	CDC5L	2	affinity chromatography technology	Ertych N (2016)	1
PRKN	1	UBE2B	3	pull down	Kazlauskaite A (2014)	1
UBE2N	1	NBN	1	pull down	Lu CS (2012)	1
RPA2	0	NBN	1	affinity chromatography technology	Marechal A (2014)	1
NBN	1	PHRF1	7	affinity chromatography technology, affinity chromatography technology	Chang CF (2015), Chang CF (2015)	2
SNW1	0	MRE11	3	affinity chromatography technology	Lleres D (2010)	1
MDC1	8	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, imaging technique, imaging technique	Matsuoka S (2007), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Lou Z (2003), Mok MT (2010), Au WW (2005)	7
H2AFX	1	RAD50	3	imaging technique, affinity chromatography technology	Paull TT (2000), Lukas C (2004)	2
TERF1	1	RAD50	3	affinity chromatography technology	Giannone RJ (2010)	1
BLM	2	ATR	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Davies SL (2004), Davies SL (2004), Davies SL (2004)	3
SLX4	6	RPA1	0	affinity chromatography technology	Ouyang J (2015)	1
RNF8	2	VRK1	0	affinity chromatography technology	Monsalve DM (2016)	1
H2AFX	1	MRE11	3	affinity chromatography technology, imaging technique, affinity chromatography technology	Lukas C (2004), Kobayashi J (2002), Kobayashi J (2002)	3
TERF1	1	MTOR	14	affinity chromatography technology	Takai H (2007)	1
OFD1	3	NBN	1	affinity chromatography technology	Gupta GD (2015)	1
RAD50	3	RFC1	1	biochemical	Wang Y (2000)	1
NCL	1	MDM2	2	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Saxena A (2006), Bhatt P (2011), Bhatt P (2011), Miyamoto-Sato E (2010), Okoro DR (2013), Saxena A (2006), Saxena A (2006)	7
POU5F1	0	PAXIP1	1	affinity chromatography technology	Oliviero G (2015)	1
ATRX	7	XRCC5	5	affinity chromatography technology	Leung JW (2013)	1