Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
PCK1 5105 PHOSPHOENOLPYRUVATE CHEMBL1235228 DrugBank 17139284, 17016423
PCK1 5105 CHEMBL120708 CHEMBL120708 DrugBank 17139284, 17016423, 10592235

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
PCK1 rs4810083 T metformin efficacy no Treatment success was defined as 1) achieving HbA1c <7 % and 2) absolute reduction in HbAlc after 6-months of metformin therapy. The relationships between genotypes and outcomes were evaluated using multivariate logistic and linear models. Allele T is not associated with response to metformin in people with Diabetes Mellitus as compared to allele C. 25327507 1296666461