Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
GAL 51083 PRASTERONE CHEMBL90593 NCI 12195234
GAL 51083 LIOTHYRONINE SODIUM CHEMBL1201119 NCI 12147214
GAL 51083 ESTRADIOL BENZOATE CHEMBL282575 NCI 14666144
GAL 51083 HYDROCORTISONE CHEMBL389621 NCI 17982695

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
GAL rs948854 C antidepressants efficacy yes This was specific to premenopausal women(not seen in postmenopausal women or in men). The same allele was associated with more severe vegetative but not cognitive depressive symptoms. Patients were on a variety of therapies, with the three largest groups being SSRIs,Tricyclics, and Mirtazapine. Allele C is associated with decreased response to antidepressants, benzodiazepine derivatives, mirtazapine or Selective serotonin reuptake inhibitors in women Depressive Disorder, Major as compared to allele T. 20237460 981754640