PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
UBC 7 RLIM 1 affinity chromatography technology Matsumoto M (2005) 1
UBXN1 0 UNK 3 biochemical Havugimana PC (2012) 1
EGFR 5 RLIM 1 affinity chromatography technology Yao Z (2017) 1
HDAC2 1 SS18L1 2 two hybrid Ravasi T (2010) 1
HDAC2 1 ESR1 0 affinity chromatography technology, affinity chromatography technology Itoh Y (2007), Tarallo R (2011) 2
SS18L1 2 RLIM 1 two hybrid Ravasi T (2010) 1
UNK 3 RLIM 1 affinity chromatography technology Murn J (2015) 1
UBC 7 TOLLIP 3 pull down, pull down, pull down, biochemical, pull down, pull down, pull down, pull down Fenner BJ (2009), Nathan JA (2013), Mitra S (2013), Mitra S (2013), Shih SC (2003), Lu K (2014), Lu K (2014), Zhang X (2017) 8
SIAH1 2 UBE2D1 0 two hybrid, two hybrid, pull down, pull down, pull down Matsuzawa SI (2001), Markson G (2009), Dimitrova YN (2010), Rott R (2008), Liu QY (2008) 5
NR4A1 4 RLIM 1 affinity chromatography technology Zhou F (2014) 1
MDM2 2 UBC 7 pull down, enzymatic study, enzymatic study Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007) 3
UBXN1 0 UBC 7 pull down, pull down, affinity chromatography technology, pull down, pull down, pull down Wu-Baer F (2010), Fenner BJ (2009), Alexandru G (2008), LaLonde DP (2011), McNeill H (2004), Zhang X (2017) 6
UBE2D1 0 RLIM 1 two hybrid, pull down, pull down, pull down Markson G (2009), Gontan C (2012), Her YR (2009), Gao K (2016) 4
STMN1 0 RLIM 1 affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology Chen X (2014), Chen X (2014), Chen X (2014), Chen X (2014), Li C (2015), Li C (2015) 6
SMURF2 3 UBC 7 enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down Maspero E (2013), Zhang L (2013), Kristariyanto YA (2015), Mari S (2014), Zhang Y (2017) 5
UBE2D3 1 SIAH1 2 two hybrid, two hybrid, pull down, pull down, pull down van Wijk SJ (2009), Markson G (2009), Liu M (2012), Mei Y (2007), Kim SY (2009) 5
SMURF2 3 UBE2D3 1 pull down, pull down, pull down, pull down, pull down, pull down, pull down Kim S (2010), Nie J (2010), Lu K (2011), Maspero E (2013), Kristariyanto YA (2015), Mari S (2014), Emanuelli A (2017) 7
UBE2D4 0 RLIM 1 two hybrid Markson G (2009) 1
LHX3 0 RLIM 1 pull down Bach I (1999) 1
TOLLIP 3 RLIM 1 affinity chromatography technology Li S (2011) 1
SIAH1 2 RLIM 1 affinity chromatography technology Kraemer OH (2008) 1
UBE2E2 1 HDAC2 1 affinity chromatography technology Kraemer OH (2008) 1
TNFAIP3 3 UBC 7 x-ray crystallography, enzymatic study, pull down, pull down, x-ray crystallography, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, x-ray crystallography, pull down Bosanac I (2010), Bremm A (2010), Fenner BJ (2009), Tokunaga F (2012), Tokunaga F (2012), Verhelst K (2012), Mevissen TE (2013), Komander D (2009), Evans PC (2004), Skaug B (2011), Bohgaki M (2008), Boone DL (2004), Mevissen TE (2016), Mevissen TE (2016) 14
UBE2D1 0 UNK 3 biochemical Havugimana PC (2012) 1
UBC 7 UBE2D3 1 affinity chromatography technology, two hybrid, x-ray crystallography, pull down, pull down, pull down Matsumoto M (2005), Vinayagam A (2011), Pruneda JN (2014), Li Y (2014), Poyurovsky MV (2007), Zhang X (2017) 6
UBXN1 0 RLIM 1 affinity chromatography technology, affinity chromatography technology Alexandru G (2008), Raman M (2015) 2
RLIM 1 LNX2 2 two hybrid Woodsmith J (2012) 1
MDM2 2 UBE2E2 1 pull down, pull down David Y (2011), Yamauchi T (2014) 2
UBE2D4 0 SIAH1 2 two hybrid van Wijk SJ (2009) 1
SIN3A 13 RLIM 1 affinity chromatography technology Bach I (1999) 1
TNFAIP3 3 RLIM 1 two hybrid Hayes SD (2012) 1
STAT6 1 RLIM 1 two hybrid Ravasi T (2010) 1
NR4A1 4 AXIN2 1 affinity chromatography technology Zhou F (2014) 1
LDB1 2 ESR1 0 pull down Johnsen SA (2009) 1
DNAJB2 0 RLIM 1 affinity chromatography technology Huttlin EL (2017) 1
BAG6 2 UBXN1 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Raman M (2015), Raman M (2015), Raman M (2015) 3
UBE2D1 0 UBC 7 x-ray crystallography Bosanac I (2010) 1
RLIM 1 MDM2 2 affinity chromatography technology, pull down, pull down, enzymatic study Gao K (2016), Gao K (2016), Gao K (2016), Gao K (2016) 4
UBE2D3 1 RLIM 1 two hybrid Markson G (2009) 1
SIAH1 2 TOLLIP 3 two hybrid Rolland T (2014) 1
RLIM 1 RLIM 1 affinity chromatography technology Johnsen SA (2009) 1
UBE2E2 1 SIAH1 2 pull down, affinity chromatography technology, affinity chromatography technology Kraemer OH (2008), Kraemer OH (2008), Lee JT (2008) 3
RLIM 1 ESR1 0 affinity chromatography technology, affinity chromatography technology, pull down Johnsen SA (2009), Johnsen SA (2009), Johnsen SA (2009) 3
TNFAIP3 3 UBE2D1 0 pull down, pull down Wertz IE (2004), Lee JH (2017) 2
UBE2E2 1 RLIM 1 two hybrid, affinity chromatography technology Markson G (2009), Kraemer OH (2008) 2
EGFR 5 SMURF2 3 affinity chromatography technology, affinity chromatography technology, pull down Ray D (2011), Ray D (2011), Ray D (2011) 3
MDM2 2 UBE2D3 1 pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down Yadavilli S (2009), Nie J (2010), Minsky N (2004), Wang X (2011), Sionov RV (2001), Oh W (2010), Zhu Y (2009), Latini P (2011), Jung CR (2010), David Y (2011), Ye B (2013), Cheng Q (2014), Saville MK (2004), Yamauchi T (2014), Jin M (2017) 15
UBE2D1 0 MDM2 2 two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down Singh RK (2007), Poyurovsky MV (2007), Li M (2003), Yogosawa S (2003), Honda R (1997), Sun XX (2011), Singh RK (2007), Taira N (2010), Fu X (2010), Wang KS (2011), Wang X (2004), Sehat B (2008), Wawrzynow B (2007), Burch L (2004), Frazier DP (2012), Huart AS (2012), Pettersson S (2009), Gama V (2009), Demma M (2010), Chymkowitch P (2011), Yan C (2010), Yang Y (2013), Ranaweera RS (2013), Siepe D (2009), Shi D (2009), Uchiki T (2009), Grossman SR (2003), Xirodimas DP (2004), Saville MK (2004), Liu T (2015), Batuello CN (2015), Fraser JA (2015), Yamauchi T (2014), Liu D (2016), McClurg UL (2016), Landre V (2017) 36
UNK 3 HDAC2 1 affinity chromatography technology Murn J (2015) 1
LDB1 2 TOLLIP 3 two hybrid Rual JF (2005) 1
SMURF2 3 UBE2D2 0 pull down Kristariyanto YA (2015) 1
RLIM 1 SNX17 0 two hybrid Wang J (2011) 1
UBE2D1 0 UBE2D2 0 biochemical Havugimana PC (2012) 1
BAG6 2 RLIM 1 affinity chromatography technology Rodrigo-Brenni MC (2014) 1
LDB1 2 RLIM 1 affinity chromatography technology, affinity chromatography technology Xu Z (2007), Howard PW (2010) 2
RLIM 1 UPF3B 6 affinity chromatography technology Huttlin EL (2017) 1
MDM2 2 RPS14 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wei S (2012), Zhou X (2012), Zhou X (2012), Zhang J (2012), Zhang J (2012), Mukhopadhyay R (2016), Mukhopadhyay R (2016) 7
EGFR 5 ESR1 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hitosugi T (2007), Hitosugi T (2007), Yao Z (2017) 3
ESR1 0 RPS14 0 affinity chromatography technology Tarallo R (2011) 1
RLIM 1 PDLIM1 1 affinity chromatography technology, affinity chromatography technology Johnsen SA (2009), Johnsen SA (2009) 2
RLIM 1 SMURF2 3 imaging technique, affinity chromatography technology, affinity chromatography technology, pull down Huang Y (2011), Huang Y (2011), Huang Y (2011), Huang Y (2011) 4
AXIN2 1 RLIM 1 affinity chromatography technology Zhou F (2014) 1
LNX2 2 UBE2D2 0 pull down Nayak D (2015) 1
EGFR 5 UBC 7 affinity chromatography technology, affinity chromatography technology Tong J (2009), Bishop N (2002) 2
ESR1 0 MDM2 2 pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001) 8
SMURF2 3 UBE2D1 0 pull down, pull down, enzymatic study, affinity chromatography technology, pull down Kim S (2010), Shukla S (2014), Shukla S (2014), Shukla S (2014), Kristariyanto YA (2015) 5
UBE2E1 1 RLIM 1 two hybrid Markson G (2009) 1
DNAJB2 0 UBC 7 affinity chromatography technology, pull down, two hybrid Westhoff B (2005), Fenner BJ (2009), Westhoff B (2005) 3
UBE2D2 0 UBC 7 x-ray crystallography, x-ray crystallography, enzymatic study, pull down, pull down Juang YC (2012), Dou H (2012), Sheng Y (2012), Buetow L (2015), Zhang X (2017) 5
RLIM 1 REXO1 6 enzymatic study Gontan C (2012) 1
UBE2D2 0 RLIM 1 two hybrid Markson G (2009) 1
HDAC2 1 RLIM 1 affinity chromatography technology Brandl A (2012) 1
UNK 3 SIN3A 13 affinity chromatography technology Murn J (2015) 1
PDLIM1 1 ESR1 0 affinity chromatography technology, affinity chromatography technology Johnsen SA (2009), Johnsen SA (2009) 2
RLIM 1 TERF1 1 two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study Her YR (2009), Her YR (2009), Her YR (2009), Her YR (2009) 4
SIN3A 13 ESR1 0 affinity chromatography technology, affinity chromatography technology Ellison-Zelski SJ (2009), Zhu P (2006) 2
PDLIM1 1 STMN1 0 biochemical Wan C (2015) 1
MDM2 2 UBE2D2 0 pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013) 33
RLIM 1 RPS14 0 two hybrid Wang J (2011) 1
UBE2D2 0 SIAH1 2 two hybrid, two hybrid, pull down, pull down van Wijk SJ (2009), Markson G (2009), Szargel R (2009), Winter M (2008) 4
HDAC2 1 SIN3A 13 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014) 20