PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CCNE1	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Harbour JW (1999), Manenti S (1999), Horton LE (1997), Higashi H (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999)	9
RASSF1	3	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	UBE2D1	0	pull down	Kazlauskaite A (2014)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
MAP2K3	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	BUB1B	0	bioid	Coyaud E (2015)	1
BTRC	1	E2F1	0	enzymatic study	Ohta T (2001)	1
CKS2	0	CCNA1	3	pull down	Radulovic M (2010)	1
CDC14B	1	FZR1	1	affinity chromatography technology	Bassermann F (2008)	1
ANAPC11	0	UBE2S	2	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Huang NJ (2012), Wang W (2013), Frye JJ (2013), Chang L (2014), Brown NG (2014), Wu T (2010), Sedgwick GG (2013), Fukushima H (2013), Yamaguchi M (2015), Brown NG (2015), Brown NG (2014), Kelly A (2014), Kelly A (2014), Craney A (2016), Zhang S (2016), Williamson A (2011), Qiao R (2016), Brown NG (2016), Li Q (2016)	19
CCND2	2	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	HHEX	1	affinity chromatography technology	Salsi V (2016)	1
AKT1	1	TERT	7	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Kawauchi K (2005), Kim MO (2008), Ivanov AA (2017)	3
FZR1	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	NAT2	0	two hybrid	Arroyo R (2015)	1
SMURF1	4	UBE2D1	0	pull down, enzymatic study	Kristariyanto YA (2015), Andrews PS (2010)	2
NINL	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
ERBB2	6	THRSP	0	two hybrid	Arroyo R (2015)	1
SKP2	2	WEE1	2	affinity chromatography technology	Watanabe N (2004)	1
CDC27	2	CDC26	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Gmachl M (2000), Kraft C (2003), Dube P (2005), Holzmann J (2011), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003), Masuda K (2015)	8
BTRC	1	RASSF1	3	two hybrid, affinity chromatography technology, bioid, affinity chromatography technology	Vinayagam A (2011), Zhou X (2012), Coyaud E (2015), Huttlin EL (2017)	4
VHL	0	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid	Lai Y (2011), Lai Y (2011), Duan DR (1995), Minervini G (2015)	4
FGFR4	6	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
ANAPC13	0	CDC16	2	biochemical, biochemical, affinity chromatography technology, genetic interference	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Horlbeck MA (2018)	4
HSP90AA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
CDKN2A	1	HSP90AA1	7	pull down	Souza-Rodrigues E (2007)	1
PRKDC	12	CHEK2	2	enzymatic study	Chan DW (2000)	1
ANAPC13	0	CDC26	0	biochemical, affinity chromatography technology, genetic interference	Havugimana PC (2012), Huttlin EL (2017), Horlbeck MA (2018)	3
FBXO5	2	BTRC	1	pull down, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Hansen DV (2004), Loveless TB (2015), Coyaud E (2015), Huttlin EL (2017), Margottin-Goguet F (2003)	5
ANAPC4	0	ANAPC5	2	biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015)	8
LRRC46	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PDGFRA	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC2	0	ANAPC10	0	biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015)	3
AURKA	1	RASSF1	3	enzymatic study, fluorescent resonance energy transfe	Chow C (2011), Ivanov AA (2017)	2
CSF3R	2	FZR1	1	affinity chromatography technology	Erkeland SJ (2007)	1
LATS2	1	CDC23	3	affinity chromatography technology, affinity chromatography technology	Zhu C (2018), Zhu C (2018)	2
FZR1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIM1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mizuno K (2001), Mizuno K (2001), Mizuno K (2001), Shay KP (2005), Shay KP (2005)	5
MAP2K5	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SMURF1	4	NEK2	2	enzymatic study	Andrews PS (2010)	1
BTRC	1	SIRT2	1	bioid	Coyaud E (2015)	1
CDC20	1	LNP1	1	affinity chromatography technology	Salsi V (2016)	1
TRIM25	5	RNF34	1	affinity chromatography technology	Choudhury NR (2017)	1
ANAPC5	2	CDC16	2	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
CUL1	7	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Michel JJ (1998)	2
CHEK2	2	FOXM1	3	enzymatic study	Tan Y (2007)	1
CDC14A	4	CDC6	0	enzymatic study	Bremmer SC (2012)	1
ANAPC1	1	ANAPC5	2	biochemical, biochemical, affinity chromatography technology, biochemical	Sumara I (2000), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015)	4
AURKA	1	LATS2	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, fluorescent resonance energy transfe	Yabuta N (2011), Toji S (2004), Toji S (2004), Toji S (2004), Toji S (2004), Ivanov AA (2017)	6
CCNE1	1	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
FZR1	1	CDC26	0	pull down, unspecified method, biochemical, affinity chromatography technology	Vodermaier HC (2003), Vodermaier HC (2003), Masuda K (2015), Huttlin EL (2017)	4
CDT1	2	ANAPC7	2	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
FZR1	1	HSF2	2	pull down, affinity chromatography technology	Ahlskog JK (2010), Ahlskog JK (2010)	2
AURKB	2	RACGAP1	2	enzymatic study, enzymatic study	Minoshima Y (2003), Toure A (2008)	2
CDT1	2	GMNN	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2008), Ballabeni A (2004), Nishitani H (2004), Nishitani H (2004), Teer JK (2008), Roukos V (2007), Wong PG (2010), Sugimoto N (2004), Takeda DY (2005), Ramachandran N (2004), Higa LA (2003), Higa LA (2003), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	15
MDC1	8	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Townsend K (2009), Townsend K (2009), Woods NT (2012)	3
CDC20	1	ANAPC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Hein JB (2014), Lischetti T (2014), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	8
AURKB	2	TPX2	4	affinity chromatography technology	Fu J (2009)	1
CUL1	7	RACGAP1	2	affinity chromatography technology	Bennett EJ (2010)	1
ANAPC10	0	ANAPC1	1	biochemical	Havugimana PC (2012)	1
CHEK2	2	CHEK1	2	genetic interference	Srivas R (2016)	1
CCNB1	3	CDC6	0	enzymatic study	Jiang W (1999)	1
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
UBE2S	2	CDC16	2	pull down	Brown NG (2014)	1
MAP2K5	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2S	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Williamson A (2009), Brown NG (2014), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016)	7
CDK1	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MDC1	8	ANAPC1	1	affinity chromatography technology, pull down, affinity chromatography technology	Coster G (2007), Townsend K (2009), Woods NT (2012)	3
ANAPC15	0	FBXO5	2	affinity chromatography technology	Hein MY (2015)	1
CHEK2	2	BEX1	0	two hybrid	Arroyo R (2015)	1
TRIM25	5	ARHGAP32	11	affinity chromatography technology	Choudhury NR (2017)	1
RNF34	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Puliyappadamba VT (2011), Puliyappadamba VT (2011)	2
TP53	0	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	UBE2D3	1	pull down	Jin L (2008)	1
USP37	1	CDT1	2	affinity chromatography technology	Hernandez-Perez S (2016)	1
CCNB1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Di Fiore B (2010), Nishiyama A (2000), Wolthuis R (2008), Desai D (1995), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
CDK4	2	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Ivanov AA (2017)	2
CHEK2	2	CUL1	7	affinity chromatography technology	Huh J (2013)	1
BECN1	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	NEK2	2	affinity chromatography technology	Boekhout M (2015)	1
ANAPC11	0	E2F1	0	affinity chromatography technology	Nath S (2014)	1
FBXO5	2	ANAPC4	0	pull down, biochemical, affinity chromatography technology	Miller JJ (2006), Chang L (2015), Voets E (2015)	3
NEDD9	3	AURKA	1	pull down	Ice RJ (2013)	1
BTRC	1	UBE2D1	0	affinity chromatography technology	Fernandez-Sanchez ME (2010)	1
CDC23	3	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
RASSF1	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Kehn K (2004), Kehn K (2004), Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017), Denicourt C (2008), Ivanov AA (2017)	8
CDC27	2	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Lee SJ (2012), Hayes MJ (2006), Havugimana PC (2012), Vodermaier HC (2003), Tran K (2010), Wan C (2015), Hein MY (2015), Qiao R (2016), Qiao R (2016), Boldt K (2016)	18
DNM1L	3	CDK1	0	affinity chromatography technology	Malty RH (2017)	1
NF2	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	CUL1	7	affinity chromatography technology	von der Lehr N (2003)	1
BUB1B	0	CDC16	2	affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Tipton AR (2013)	2
PLK1	0	RRM2	2	biochemical	Wan C (2015)	1
CCNA2	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
MDC1	8	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Coster G (2007), Coster G (2007), Townsend K (2009), Townsend K (2009), Woods NT (2012)	5
TRIM25	5	MYC	2	affinity chromatography technology	Choudhury NR (2017)	1
CDK4	2	CHEK2	2	genetic interference	Shen JP (2017)	1
SOX2	4	CDK1	0	affinity chromatography technology	Cox JL (2013)	1
CDC16	2	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Huttlin EL (2017)	2
CDK1	0	FBXO5	2	enzymatic study	Moshe Y (2011)	1
CDC27	2	ANAPC5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Koloteva-Levine N (2004), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Havugimana PC (2012), Song MS (2011), Vodermaier HC (2003), Tran K (2010), Kelly A (2014), Craney A (2016), Qiao R (2016)	15
TACC3	1	KAT2A	1	pull down	Gangisetty O (2004)	1
USP37	1	ANAPC7	2	affinity chromatography technology, bioid	Huang X (2011), Yeh C (2015)	2
PDGFRA	3	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	RRM2	2	affinity chromatography technology	Truman AW (2015)	1
CDK6	0	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TPX2	4	UBE2S	2	biochemical	Havugimana PC (2012)	1
FZR1	1	MTA3	3	two hybrid	Arroyo R (2015)	1
TERT	7	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	FBXO5	2	genetic interference	Toyoshima M (2012)	1
TEAD2	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	UBE2D3	1	pull down	Chong RA (2014)	1
TP53	0	CDC14A	4	two hybrid, affinity chromatography technology, pull down	Li L (2000), Li L (2000), Li L (2000)	3
PTEN	24	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
FZR1	1	UBE2K	0	pull down	Jin L (2008)	1
MDC1	8	ANAPC2	0	affinity chromatography technology	Woods NT (2012)	1
FZR1	1	CDC25A	2	affinity chromatography technology, pull down, enzymatic study	Gao D (2009), Donzelli M (2002), Donzelli M (2002)	3
CDC6	0	CDKN2A	1	pull down	Ramachandran N (2004)	1
GLIS2	2	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	GLIS2	2	affinity chromatography technology	Choudhury NR (2017)	1
TP53	0	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC2	0	ANAPC7	2	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003)	3
VHL	0	CHEK2	2	affinity chromatography technology, enzymatic study	Roe JS (2011), Roe JS (2011)	2
HSP90AA1	7	PRKDC	12	affinity chromatography technology	Falsone SF (2005)	1
HSP90AA1	7	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu W (2001), Jeong JH (2008), Mollapour M (2010), Citri A (2002), Jung Y (2007), Suzuki T (2011), Tsutsumi S (2012), Taipale M (2012), Bali P (2005), Woodford MR (2016), Yan YY (2011), Yan YY (2011)	12
CDC25A	2	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Galaktionov K (1991), Li X (2016)	2
FZR1	1	CCND1	1	affinity chromatography technology	Pawar SA (2010)	1
TRIM25	5	HSP90AA1	7	affinity chromatography technology	Choudhury NR (2017)	1
ARNT	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTTG1	0	BTRC	1	affinity chromatography technology	Limon-Mortes MC (2008)	1
CDC6	0	UBE2K	0	two hybrid	Wang J (2011)	1
FZR1	1	NEK2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sedgwick GG (2012), Boekhout M (2015), Lee SB (2015)	3
ANAPC7	2	E2F1	0	affinity chromatography technology	Nath S (2014)	1
MYC	2	KAT2A	1	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	McMahon SB (2000), Faiola F (2005), Liu X (2008), Conacci-Sorrell M (2010), Liu X (2003), Liu X (2003), Ivanov AA (2017)	7
PDGFRA	3	VHL	0	genetic interference	Shen JP (2017)	1
CCNE1	1	SKP2	2	pull down, enzymatic study	Yeh KH (2001), Enchev RI (2012)	2
CDC20	1	ID1	0	affinity chromatography technology, affinity chromatography technology	Wang X (2008), Wang X (2008)	2
PRKN	1	AURKB	2	affinity chromatography technology	Lee SB (2015)	1
GLIS2	2	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Hu J (2004), Hu J (2004), Hu J (2004), Hu J (2004), Zhang Y (2012)	5
MYC	2	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HECW2	13	ANAPC5	2	affinity chromatography technology	Lu L (2013)	1
MYC	2	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC13	0	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
FZR1	1	E2F3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ping Z (2012), Ping Z (2012), Ping Z (2012)	3
NF2	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
MAP2K5	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TAS2R13	2	CDC20	1	affinity chromatography technology	Ohoka N (2010)	1
FZR1	1	GMNN	0	affinity chromatography technology, enzymatic study, pull down	Pfleger CM (2001), Williamson A (2011), Williamson A (2011)	3
LATS2	1	RASSF1	3	fluorescent resonance energy transfe, pull down, fluorescent resonance energy transfe	Mo XL (2015), Mo XL (2015), Ivanov AA (2017)	3
FZR1	1	UBE2D1	0	pull down	Jin L (2008)	1
FGFR4	6	THRSP	0	two hybrid	Arroyo R (2015)	1
CDC16	2	CCNB1	3	affinity chromatography technology	van Zon W (2010)	1
CHEK2	2	TP53	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Louria-Hayon I (2003), Shieh SY (2000), Bjorling-Poulsen M (2005), Hirao A (2000), Adams CJ (2008)	5
AURKA	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA1	3	CDK2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, imaging technique	Sweeney C (1996), Yang R (1997), Yang R (1997), Mueller-Tidow C (2001), Brown NR (1999), Niida H (2005), Yam CH (2000), Wang H (2009), Narayanan R (2005), Harwell RM (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Peiretti A (2003), Pan ZQ (1993), Kim KS (2002), Lyapina SA (1998), Desai D (1995), Thomas DM (2004), Johnson LN (2002), Rohaly G (2005), Chen TC (2014)	22
AURKB	2	BUB1B	0	affinity chromatography technology	Ferrand A (2009)	1
NUP98	5	PTTG1	0	affinity chromatography technology, affinity chromatography technology	Jeganathan KB (2006), Jeganathan KB (2006)	2
FZR1	1	TPX2	4	affinity chromatography technology, affinity chromatography technology	Stewart S (2005), Stewart S (2005)	2
NINL	1	CDC27	2	affinity chromatography technology	Wang Y (2007)	1
CHEK2	2	ERBB2	6	genetic interference	Shen JP (2017)	1
CDC20	1	HHEX	1	affinity chromatography technology	Salsi V (2016)	1
DAXX	5	TP53	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, unspecified method	Tang J (2006), Kim EJ (2003), Kim EJ (2003), Kim EJ (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Wethkamp N (2011), Zhao LY (2004), Zhao LY (2004), Zhao LY (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Zhao LY (2004), Zhao LY (2004), Zhang H (2013), Zhang H (2013), Chen TC (2014), Li Z (2017)	23
ANAPC10	0	HOXD13	0	affinity chromatography technology	Salsi V (2016)	1
SOX2	4	SRP68	2	affinity chromatography technology	Cox JL (2013)	1
CDC26	0	CDC16	2	pull down, x-ray crystallography, two hybrid, two hybrid, biochemical, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Wang J (2009), Wang J (2009), Wang J (2011), Rolland T (2014), Wan C (2015), Yu H (2011), Hein MY (2015), Masuda K (2015), Masuda K (2015), Masuda K (2015), Huttlin EL (2017)	11
ANAPC15	0	RRM2	2	affinity chromatography technology	Hein MY (2015)	1
CDC27	2	ANAPC15	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Uzunova K (2012), Hein MY (2015)	3
CCND2	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017)	3
BECN1	2	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	NUP98	5	affinity chromatography technology	Salsi V (2016)	1
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
SIRT2	1	CDC20	1	enzymatic study	Kim HS (2011)	1
CCNA2	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Higashi H (1996), Knudsen ES (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Nakanishi M (1999)	7
CHEK2	2	CCL5	1	two hybrid	Arroyo R (2015)	1
FZR1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Lv XB (2010), Lv XB (2010)	2
PLK1	0	TP53	0	enzymatic study	Dias SS (2009)	1
ANAPC4	0	CDC26	0	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Masuda K (2015)	6
USP37	1	CUL1	7	affinity chromatography technology	Burrows AC (2012)	1
SKP2	2	CCNB1	3	affinity chromatography technology	Bashir T (2010)	1
CCNB1	3	ANAPC10	0	affinity chromatography technology	Voets E (2015)	1
ERBB2	6	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
CDT1	2	CCNA2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teer JK (2008), Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
HECW2	13	CDC16	2	affinity chromatography technology	Lu L (2013)	1
CDK4	2	MYC	2	enzymatic study, two hybrid, fluorescent resonance energy transfe	Anders L (2011), Wang J (2011), Ivanov AA (2017)	3
ERBB2	6	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Dube P (2005), Holzmann J (2011), Lee SJ (2012), Hayes MJ (2006), Havugimana PC (2012), Gmachl M (2000), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Gmachl M (2000), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
CCND2	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	E2F1	0	affinity chromatography technology	Nath S (2014)	1
PRKN	1	CUL1	7	affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	3
BECN1	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC16	2	ANAPC7	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Havugimana PC (2012), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	5
ANAPC15	0	FZR1	1	affinity chromatography technology	Hein MY (2015)	1
SPRTN	0	FZR1	1	affinity chromatography technology	Mosbech A (2012)	1
ARNT	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKIL	3	FZR1	1	affinity chromatography technology	Stroschein SL (2001)	1
HCCS	0	FZR1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAP2K5	1	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PHF8	6	CDC26	0	affinity chromatography technology	Lim HJ (2013)	1
ANAPC4	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Izawa D (2011), Di Fiore B (2015), Voets E (2015)	3
FZR1	1	RNF157	3	affinity chromatography technology	Dogan T (2017)	1
ANAPC4	0	DCPS	1	biochemical	Chang L (2014)	1
MDC1	8	CDC27	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Coster G (2007), Coster G (2007), Townsend K (2009), Townsend K (2009), Townsend K (2009), Coster G (2012)	6
AURKB	2	TTK	4	affinity chromatography technology	Huttlin EL (2015)	1
UBE2S	2	VHL	0	pull down, pull down, enzymatic study, affinity chromatography technology	Lim JH (2016), Lim JH (2016), Lim JH (2016), Lim JH (2016)	4
SOX2	4	ANAPC4	0	affinity chromatography technology	Cox JL (2013)	1
FZR1	1	BRSK2	5	affinity chromatography technology	Li R (2012)	1
FGFR4	6	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	HOXD13	0	affinity chromatography technology	Salsi V (2016)	1
ERBB2	6	RRM2	2	genetic interference	Shen JP (2017)	1
HSP90AA1	7	HIF1A	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hogenesch JB (1997), Qian DZ (2006), Kong X (2006), Kubo T (2004), Zhou J (2004), Fu B (2007), Choi YK (2010), Choi YK (2010), Lee JM (2011), Liu YV (2007), Liu YV (2007), Katschinski DM (2004), Katschinski DM (2004), Katschinski DM (2004), Trisciuoglio D (2010), Trisciuoglio D (2010), Ueda K (2008), Sun H (2013), Kawanami D (2009), Prince TL (2015), Prince TL (2015), Isaacs JS (2004), Lee SH (2015)	23
CDT1	2	CDC6	0	pull down, pull down, imaging technique	Sugimoto N (2008), Ramachandran N (2004), Sugimoto N (2015)	3
AURKA	1	BTRC	1	affinity chromatography technology	Irelan JT (2007)	1
CCND1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Lin DI (2006), Wei S (2008), Yu ZK (1998)	4
CCNB1	3	CKS2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Radulovic M (2010), Hein MY (2015), Huttlin EL (2017)	4
PDGFRA	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TK1	0	GLB1	3	two hybrid	Vinayagam A (2011)	1
TERT	7	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
TERT	7	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAK	3	FZR1	1	affinity chromatography technology, enzymatic study	Wang LY (2012), Wang LY (2012)	2
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
FBXO5	2	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Moshe Y (2011), Miller JJ (2006), Miller JJ (2006), Miller JJ (2006), Miller JJ (2006), Huttlin EL (2017)	6
CDC27	2	ANAPC1	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Sumara I (2000), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Holzmann J (2011), Havugimana PC (2012), Vodermaier HC (2003), Tran K (2010), Wan C (2015), Qiao R (2016), Qiao R (2016)	12
ANAPC10	0	ANAPC7	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
FZR1	1	GRIA1	5	affinity chromatography technology	Fu AK (2011)	1
AURKA	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HIF1A	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	UBE2S	2	pull down	Kazlauskaite A (2014)	1
FZR1	1	USP37	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2011), Huang X (2011), Saxena N (2014), Huttlin EL (2017)	4
CDC20	1	ANAPC5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Qiao R (2016)	6
LATS2	1	ANAPC2	0	affinity chromatography technology	Zhu C (2018)	1
FZR1	1	CYP17A1	5	two hybrid	Arroyo R (2015)	1
ANAPC13	0	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
CKS2	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
STK11	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTGF	1	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
CDC20	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stewart S (2005), Jia L (2011), Zhang Y (2001), Fogeron ML (2013), Lee SB (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016)	9
CDK4	2	CDKN2A	1	affinity chromatography technology, unspecified method, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Fahraeus R (1996), Li J (2004), Sugimoto M (1999), Serrano M (1993), Serrano M (1993), Serrano M (1993), Coleman KG (1997), Zhang Y (1998), Haddad MM (1999), Li J (2002), Li J (2002), Lal G (2000), Yarbrough WG (1999), Della Torre G (2001), Jones R (2007), Jones R (2007), Ramachandran N (2004), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Fei HJ (2017), Huttlin EL (2017), Ivanov AA (2017)	25
CHEK1	2	FZR1	1	genetic interference	Srivas R (2016)	1
CDK6	0	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Sugimoto M (1999), Lin J (2001), Sweeney KJ (1997), Ruas M (2007), Shu F (2007), Ramachandran N (2004), Ghiani C (2001)	7
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
CHEK2	2	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
CDKN2A	1	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Herkert B (2010), Amente S (2007), Zhang Q (2013), Ivanov AA (2017)	4
MET	7	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	FOXM1	3	affinity chromatography technology	Taipale M (2012)	1
AURKA	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Tsunematsu T (2013), Tsunematsu T (2013), Tsunematsu T (2013)	3
LATS2	1	AURKB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yabuta N (2011), Yabuta N (2011), Yabuta N (2011)	3
CHEK2	2	WEE1	2	genetic interference	Srivas R (2016)	1
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	CDC16	2	affinity chromatography technology	Zhu C (2018)	1
CDK6	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUEDC2	0	CDC27	2	affinity chromatography technology, affinity chromatography technology	Gao YF (2011), Zhang WN (2013)	2
TRIM25	5	PRKDC	12	affinity chromatography technology	Choudhury NR (2017)	1
C16orf87	0	ANAPC7	2	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	HSPA2	3	affinity chromatography technology	Horikawa I (2014)	1
FZR1	1	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
USP37	1	CDC16	2	bioid	Yeh C (2015)	1
RB1	2	CCNA1	3	pull down, affinity chromatography technology, enzymatic study	Yang R (1999), Yang R (1999), Zarkowska T (1997)	3
USP37	1	CCNB1	3	affinity chromatography technology	Huang X (2011)	1
FZR1	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	E2F1	0	affinity chromatography technology, pull down	Eymin B (2001), Eymin B (2001)	2
HSP90AA1	7	EPHA4	3	affinity chromatography technology	Taipale M (2012)	1
PIM1	2	MYC	2	affinity chromatography technology, affinity chromatography technology	Zippo A (2007), Zippo A (2007)	2
FZR1	1	PRKN	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
FZR1	1	THRSP	0	two hybrid	Arroyo R (2015)	1
E2F1	0	CCNA1	3	pull down, affinity chromatography technology, pull down	Yang R (1999), Yang R (1999), Ji P (2006)	3
FZR1	1	RRM2B	1	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	SKP2	2	affinity chromatography technology	Choudhury NR (2017)	1
RBBP8	1	FANCD2	3	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, genetic interference, imaging technique, affinity chromatography technology	Yeo JE (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Murina O (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014), Unno J (2014)	12
MCPH1	4	MDC1	8	imaging technique	Rai R (2006)	1
EYA1	4	MYC	2	enzymatic study, affinity chromatography technology, affinity chromatography technology	Li J (2017), Li J (2017), Li J (2017)	3
PDGFRA	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	FOXM1	3	enzymatic study	Anders L (2011)	1
AKT1	1	THRSP	0	two hybrid	Arroyo R (2015)	1
RRM2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FZR1	1	USP1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Cataldo F (2013), Cotto-Rios XM (2011), Cotto-Rios XM (2011), Cotto-Rios XM (2011)	4
TERT	7	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA4	3	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Fu AK (2011), Fu AK (2011)	2
ANAPC4	0	LNP1	1	affinity chromatography technology	Salsi V (2016)	1
CDC20	1	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Voets E (2015), Kelly A (2014), Craney A (2016)	4
CDKN2A	1	HIF1A	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Fatyol K (2001), Fatyol K (2001), Ivanov AA (2017)	3
RASSF1	3	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	MET	7	genetic interference	Shen JP (2017)	1
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
CDKN2A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Zhang Y (2003), Zhang Y (2003), Rizos H (2003), Zhang Y (1998), Zhang Y (1998), Li L (2010), Li L (2010), Kamijo T (1998), Stott FJ (1998), Ivanov AA (2017)	10
STK11	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	MAP3K5	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	McLaughlin NJ (2006), McLaughlin NJ (2006), Yoon KW (2009), Yoon KW (2009), Ivanov AA (2017)	5
FZR1	1	AKT1S1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	LATS2	1	enzymatic study, enzymatic study	Okada N (2011), Suzuki H (2013)	2
USP37	1	CDC20	1	affinity chromatography technology	Huang X (2011)	1
TEAD2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	BUB1B	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Fang G (2002), Fang G (2002), Wu H (2000), Wu H (2000), Wu H (2000), Kallio MJ (2002), Sudakin V (2001), Sudakin V (2001), Skoufias DA (2001), Nilsson J (2008), Ho CY (2010), Ho CY (2010), Garnett MJ (2009), Hutchins JR (2010), Di Fiore B (2010), Di Fiore B (2010), Mansfeld J (2011), Jia L (2011), Braunstein I (2007), Eytan E (2008), Eytan E (2008), Ma HT (2011), Miniowitz-Shemtov S (2012), Tang Z (2001), Tang Z (2001), Tang Z (2001), Tang Z (2001), Bolanos-Garcia VM (2011), Ge S (2009), Liu L (2007), Westhorpe FG (2011), Westhorpe FG (2011), Kwan PS (2013), Tian W (2012), Tian W (2012), Tian W (2012), Santaguida S (2011), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Han JS (2014), Izawa D (2014), Hein JB (2014), So J (2015), Scialpi F (2015), Scialpi F (2015), Diaz-Martinez LA (2015), Diaz-Martinez LA (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Voets E (2015), Chen TC (2014), Lischetti T (2014), Lischetti T (2014), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Huttlin EL (2017), Izawa D (2012), Jia L (2016), Jia L (2016), Hein JB (2016), Kaisari S (2017)	73
ANAPC1	1	CDC26	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
FZR1	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK2	2	LATS2	1	enzymatic study	Okada N (2011)	1
CDC20	1	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kallio MJ (2002), Kallio M (1998), Nilsson J (2008), Hutchins JR (2010), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Listovsky T (2013), Qiao R (2016), Izawa D (2012)	12
CDC6	0	CDK2	0	affinity chromatography technology, enzymatic study	Saha P (1998), Jiang W (1999)	2
CHEK1	2	CDC14A	4	genetic interference	Srivas R (2016)	1
PDGFRA	3	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
FZR1	1	DNM1L	3	enzymatic study, pull down	Horn SR (2011), Horn SR (2011)	2
FZR1	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EMILIN1	1	CDC23	3	affinity chromatography technology	Ban KH (2007)	1
TP53	0	SOX4	5	pull down, affinity chromatography technology, affinity chromatography technology	Pan X (2009), Pan X (2009), Pan X (2009)	3
PRKN	1	BECN1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Choubey V (2014), Lonskaya I (2014), Lonskaya I (2014), Lonskaya I (2014)	4
ANAPC10	0	ANAPC4	0	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Voets E (2015)	8
WEE1	2	RB1	2	genetic interference	Srivas R (2016)	1
CKS1B	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
ZC3HC1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down	Bassermann F (2007), Bassermann F (2005), Bassermann F (2005)	3
CCND1	1	CDK5	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK4	2	CDC6	0	enzymatic study	Anders L (2011)	1
CDT1	2	CUL1	7	affinity chromatography technology	Li X (2003)	1
UBE2S	2	ANAPC7	2	pull down	Brown NG (2014)	1
CDKN2B	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC11	0	UBE2K	0	pull down, pull down, pull down	Bassermann F (2008), Rodrigo-Brenni MC (2007), Van Voorhis VA (2014)	3
CDK2	0	LATS2	1	enzymatic study	Toji S (2004)	1
FZR1	1	ZC3HC1	1	enzymatic study, affinity chromatography technology	von Klitzing C (2011), von Klitzing C (2011)	2
MAP3K5	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	PTTG1	0	enzymatic study	Lee SB (2015)	1
PTEN	24	VHL	0	genetic interference	Shen JP (2017)	1
RB1	2	CDC27	2	affinity chromatography technology, biochemical, two hybrid, pull down	Binne UK (2007), Binne UK (2007), Chen PL (1995), Chen PL (1995)	4
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
STK11	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	HIF1A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOX4	5	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO5	2	CDC16	2	affinity chromatography technology, pull down, affinity chromatography technology	Miller JJ (2006), Miller JJ (2006), Hein MY (2015)	3
PTEN	24	BEX1	0	two hybrid	Arroyo R (2015)	1
MET	7	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Taipale M (2012), Zanon A (2013)	3
HIF1A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	LNP1	1	affinity chromatography technology	Salsi V (2016)	1
CDK4	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	VHL	0	genetic interference	Shen JP (2017)	1
CCNE1	1	CDK4	2	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
PRKN	1	DNM1L	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang H (2011), Wang H (2011), Wang H (2011), Wang H (2011)	4
LATS2	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	FANCD2	3	genetic interference	Aggarwal M (2013)	1
FZR1	1	PTTG1	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Pfleger CM (2001), Jin L (2008), Tian W (2012), He J (2013), Wang W (2013), Van Voorhis VA (2014), Gmachl M (2000), Wu T (2010), Vodermaier HC (2003), Jeganathan KB (2006), Yamaguchi M (2015), Brown NG (2015), Williamson A (2011), Qiao R (2016), Brown NG (2016)	15
MDC1	8	CDC20	1	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Townsend K (2009), Townsend K (2009), Townsend K (2009), Townsend K (2009), Woods NT (2012)	5
AURKB	2	RASSF1	3	enzymatic study	Chow C (2011)	1
FGFR4	6	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KMT5A	2	CUL1	7	affinity chromatography technology	Wang Z (2015)	1
ANAPC1	1	CDC23	3	biochemical, biochemical, affinity chromatography technology	Sumara I (2000), Havugimana PC (2012), Hein MY (2015)	3
HIF1A	1	RB1	2	unspecified method, pull down, affinity chromatography technology	Budde A (2005), Budde A (2005), Budde A (2005)	3
AURKB	2	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
CDC23	3	CDC26	0	affinity chromatography technology	Hein MY (2015)	1
STK11	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KAT2A	1	CDK2	0	enzymatic study	Mateo F (2009)	1
E2F1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology	Xu M (1994), Xu M (1994), Schulman BA (1998)	3
ANAPC13	0	ANAPC5	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
CDK6	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM33	4	CDC20	1	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Sedgwick GG (2012)	2
IST1	0	ANAPC2	0	affinity chromatography technology	Zhang X (2011)	1
ANAPC2	0	ANAPC4	0	biochemical, biochemical, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Boekhout M (2015)	11
CDC14B	1	PHF8	6	bioid	St-Denis N (2016)	1
RASSF1	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
SMURF1	4	UBE2K	0	enzymatic study	Andrews PS (2010)	1
NF2	1	HIF1A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Mansfeld J (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Wolthuis R (2008), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Fogeron ML (2013), Hein JB (2014), Hein JB (2014), Voets E (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Izawa D (2012), Izawa D (2012), Izawa D (2012), Izawa D (2012), Salsi V (2016)	25
RACGAP1	2	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK5	0	HSP90AA1	7	affinity chromatography technology	Varjosalo M (2013)	1
CCNF	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2011), Jeong YT (2013), Choudhury R (2017), Reitsma JM (2017)	4
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
BECN1	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	RASSF1	3	unspecified method	Kim ST (1999)	1
UBE2S	2	ANAPC5	2	pull down	Brown NG (2014)	1
FZR1	1	ANAPC10	0	unspecified method	Vodermaier HC (2003)	1
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
PLK1	0	RBBP8	1	affinity chromatography technology	Hein MY (2015)	1
PDGFRA	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TEAD2	2	CDC27	2	affinity chromatography technology	Li X (2015)	1
CDC16	2	CDC23	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	6
HECW2	13	FZR1	1	affinity chromatography technology, pull down, enzymatic study	Lu L (2013), Lu L (2013), Lu L (2013)	3
CDC20	1	HSF2	2	pull down, affinity chromatography technology	Ahlskog JK (2010), Ahlskog JK (2010)	2
HECW2	13	TRIM25	5	affinity chromatography technology	Lu L (2013)	1
USP37	1	CDC23	3	bioid	Yeh C (2015)	1
SENP2	3	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down	Lu H (2014), Lu H (2014), Lu H (2014)	3
FZR1	1	HOXD13	0	affinity chromatography technology	Salsi V (2016)	1
TRIM25	5	CCNF	2	affinity chromatography technology	Choudhury NR (2017)	1
HSP90AA1	7	CHEK1	2	affinity chromatography technology, pull down, affinity chromatography technology	Ha K (2011), Arlander SJ (2006), Taipale M (2012)	3
CDKN2A	1	CCND1	1	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Sugimoto M (1999), Ruas M (2007), Hein MY (2015), Fei HJ (2017)	4
RASSF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2D3	1	UBE2C	1	biochemical	Wan C (2015)	1
SKP2	2	RASSF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song MS (2008), Song MS (2008), Calvisi DF (2009)	3
FZR1	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Bashir T (2010), Rosner M (2009), Rosner M (2004), Zhang H (1995), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
BECN1	2	TP53	0	affinity chromatography technology	Verma N (2017)	1
STK11	2	THRSP	0	two hybrid	Arroyo R (2015)	1
NINL	1	TP53	0	bioid	Gupta GD (2015)	1
NF2	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	NEK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2013), Sedgwick GG (2013), Voets E (2015), Boekhout M (2015), Boekhout M (2015)	5
PHF8	6	ANAPC1	1	affinity chromatography technology	Lim HJ (2013)	1
FGFR4	6	EPSTI1	0	two hybrid	Arroyo R (2015)	1
RB1	2	MAPK8	3	affinity chromatography technology	Li H (2001)	1
AURKA	1	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
ANAPC15	0	ANAPC13	0	affinity chromatography technology	Hein MY (2015)	1
FBXO5	2	CDC23	3	pull down, affinity chromatography technology	Miller JJ (2006), Hein MY (2015)	2
CDK1	0	RACGAP1	2	enzymatic study	Toure A (2008)	1
CHEK1	2	RB1	2	enzymatic study, pull down	Inoue Y (2007), Inoue Y (2007)	2
CCNA2	1	CDC20	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Di Fiore B (2010), Di Fiore B (2010), Di Fiore B (2010), Wolthuis R (2008), Wolthuis R (2008), Ge S (2009), Townsend K (2009), Di Fiore B (2010), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Huttlin EL (2017), Izawa D (2012), Hein JB (2016)	25
CDC6	0	MYC	2	pull down	Takayama M (2000)	1
FANCD2	3	FZR1	1	affinity chromatography technology, affinity chromatography technology	Lai F (2012), Lai F (2012)	2
MDC1	8	STAU1	1	affinity chromatography technology	Woods NT (2012)	1
NF2	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Kurasawa Y (1999), Kurasawa Y (1999), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015)	13
C16orf87	0	ANAPC2	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXO5	2	ANAPC11	0	pull down	Miller JJ (2006)	1
PHF8	6	CDC23	3	affinity chromatography technology	Lim HJ (2013)	1
RNF34	1	TP53	0	affinity chromatography technology	Yang W (2007)	1
USP1	4	FANCD2	3	affinity chromatography technology, enzymatic study, biochemical	Nijman SM (2005), Cohn MA (2007), Nijman SM (2005)	3
CDC20	1	NUP98	5	affinity chromatography technology	Salsi V (2016)	1
AURKB	2	CDC27	2	affinity chromatography technology	Nguyen HG (2005)	1
TRIM25	5	E2F3	0	affinity chromatography technology	Choudhury NR (2017)	1
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
RRM2B	1	RRM2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AURKA	1	DKK3	3	two hybrid	Arroyo R (2015)	1
PHF8	6	CDC16	2	affinity chromatography technology	Lim HJ (2013)	1
ANAPC15	0	CDC26	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
HSP90AA1	7	SKP2	2	affinity chromatography technology	Taipale M (2012)	1
UBE2D1	0	TRIM25	5	two hybrid, pull down, pull down, pull down, pull down	Markson G (2009), Gack MU (2007), Wang Y (2014), Ronchi VP (2012), Wang S (2016)	5
ANAPC11	0	MAK	3	two hybrid	Wang J (2011)	1
MAP2K3	1	HIF1A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Lara-Gonzalez P (2011), Mansfeld J (2011), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Eytan E (2013), Wang K (2014), Han JS (2014), Han JS (2014), Lara-Gonzalez P (2011), So J (2015), Boekhout M (2015), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
MAP2K3	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	CYP17A1	5	two hybrid	Arroyo R (2015)	1
PDGFRA	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC13	0	BUB1B	0	genetic interference	Horlbeck MA (2018)	1
BTRC	1	CCNE1	1	enzymatic study, enzymatic study	Saha A (2008), Pierce NW (2013)	2
CUEDC2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology	Gao YF (2011), Gao YF (2011)	2
C16orf87	0	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC1	1	ANAPC2	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sumara I (2000), Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003)	4
PRKDC	12	RBBP8	1	unspecified method	Kim ST (1999)	1
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
GLIS2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TTK	4	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu ST (2003), Cui Y (2010), Cui Y (2010), Liu C (2011)	4
ANAPC10	0	NUP98	5	affinity chromatography technology	Salsi V (2016)	1
C16orf87	0	ANAPC5	2	affinity chromatography technology	Huttlin EL (2017)	1
LATS2	1	NINL	1	bioid	Couzens AL (2013)	1
CDKN2A	1	BECN1	2	pull down, fluorescent resonance energy transfe	Pimkina J (2009), Ivanov AA (2017)	2
C16orf87	0	NEK2	2	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC1	1	USP1	4	affinity chromatography technology	Cotto-Rios XM (2011)	1
PTEN	24	DDB1	6	pull down	Verrastro I (2015)	1
HIF1A	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2K	0	CCNB1	3	affinity chromatography technology	Bae Y (2010)	1
CUL1	7	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina SA (1998), Huttlin EL (2015), Huttlin EL (2017)	4
MYC	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	CCNB1	3	affinity chromatography technology, pull down	Sugimoto N (2004), Sugimoto N (2004)	2
HECW2	13	KAT2A	1	affinity chromatography technology	Lu L (2013)	1
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC13	0	FBXO5	2	affinity chromatography technology	Huttlin EL (2017)	1
FZR1	1	PLK1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013), Sedgwick GG (2012), Lee SB (2015), Williamson A (2011)	5
TRIM25	5	NUP98	5	affinity chromatography technology	Choudhury NR (2017)	1
USP37	1	CDC27	2	affinity chromatography technology, bioid	Huang X (2011), Yeh C (2015)	2
HSP90AA1	7	BTRC	1	affinity chromatography technology	Taipale M (2012)	1
CCNA2	1	CDK4	2	affinity chromatography technology, affinity chromatography technology	Datta NS (1998), Kikuchi R (2014)	2
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
FZR1	1	DCPS	1	enzymatic study, enzymatic study, enzymatic study	Chang L (2014), Zhang S (2016), Li Q (2016)	3
GLIS2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	CCND2	2	pull down, pull down, fluorescent resonance energy transfe	Li J (2004), Li J (2002), Ivanov AA (2017)	3
CDK1	0	CCNF	2	affinity chromatography technology	Kong M (2000)	1
TEAD2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PHF8	6	ANAPC7	2	affinity chromatography technology	Lim HJ (2013)	1
GLIS2	2	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	CCND2	2	affinity chromatography technology	Gong Y (2014)	1
TRIM25	5	FOXM1	3	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
TRIM33	4	UBE2D3	1	pull down, pull down	Agricola E (2011), Weng L (2014)	2
AURKB	2	AURKA	1	affinity chromatography technology	Fogeron ML (2013)	1
CDC20	1	NEK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sedgwick GG (2012), Boekhout M (2015), Boekhout M (2015), Kelly A (2014)	4
FZR1	1	PTEN	24	affinity chromatography technology, pull down, affinity chromatography technology	Song MS (2011), Song MS (2011), Choi BH (2014)	3
MAP2K3	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC23	3	BUB1B	0	affinity chromatography technology	Hein MY (2015)	1
ANAPC11	0	UBE2D3	1	pull down	Choudhury R (2016)	1
PRKDC	12	HIF1A	1	affinity chromatography technology	Um JH (2004)	1
CDK6	0	MYC	2	enzymatic study, fluorescent resonance energy transfe	Anders L (2011), Ivanov AA (2017)	2
CHEK1	2	PTEN	24	genetic interference	Shen JP (2017)	1
CDC27	2	FOXM1	3	affinity chromatography technology	Park HJ (2008)	1
ERBB2	6	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
TTK	4	HSP90AA1	7	enzymatic study, affinity chromatography technology	Woodford MR (2016), Woodford MR (2016)	2
FZR1	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC13	0	ANAPC4	0	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Huttlin EL (2017)	6
CDC20	1	CUL1	7	affinity chromatography technology	Wu F (2017)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC20	1	GMNN	0	affinity chromatography technology, affinity chromatography technology	Pfleger CM (2001), Tsunematsu T (2013)	2
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
KMT5A	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Wu S (2010), Wu S (2010)	2
CDK4	2	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	EPSTI1	0	two hybrid	Arroyo R (2015)	1
TRIM25	5	MAD2L2	0	affinity chromatography technology	Choudhury NR (2017)	1
CDC20	1	CCNA1	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Ohtoshi A (2000), Ohtoshi A (2000), Gao D (2009)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
TRIM25	5	MAP2K3	1	affinity chromatography technology	Choudhury NR (2017)	1
MAP2K5	1	PDGFRA	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC2	0	CDC26	0	affinity chromatography technology, affinity chromatography technology	Gmachl M (2000), Vodermaier HC (2003)	2
FZR1	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	CCND1	1	affinity chromatography technology	Yang P (2016)	1
TK1	0	TP53	0	two hybrid, two hybrid	Stelzl U (2005), Vinayagam A (2011)	2
CCNA2	1	CDK6	0	affinity chromatography technology	Datta NS (1998)	1
SOX2	4	ANAPC1	1	affinity chromatography technology	Cox JL (2013)	1
C16orf87	0	CDC23	3	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	TERT	7	genetic interference, genetic interference	Xie L (2013), Xie L (2013)	2
LATS2	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	PRR36	4	affinity chromatography technology	Huttlin EL (2017)	1
BTRC	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	2
TK1	0	FZR1	1	affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, affinity chromatography technology	Ke PY (2004), Ke PY (2004), Ke PY (2004), Ke PY (2007), Ke PY (2007), Huttlin EL (2017)	6
AURKB	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
CDKN2A	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	ANAPC1	1	pull down, unspecified method, affinity chromatography technology	Vodermaier HC (2003), Vodermaier HC (2003), Huttlin EL (2017)	3
SIRT2	1	FZR1	1	enzymatic study	Kim HS (2011)	1
TEAD2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ID1	0	VHL	0	affinity chromatography technology	Lee SB (2016)	1
CUEDC2	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang WN (2013), Huttlin EL (2015), Huttlin EL (2017)	3
MYC	2	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
ANAPC1	1	ANAPC7	2	biochemical, biochemical, biochemical	Sumara I (2000), Havugimana PC (2012), Wan C (2015)	3
CHEK1	2	NEK2	2	biochemical	Kraemer A (2004)	1
PTTG1	0	CDC27	2	affinity chromatography technology, pull down, pull down	Jeganathan KB (2006), Miller JJ (2006), Qiao R (2016)	3
ANAPC15	0	CDC20	1	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
HECW2	13	ANAPC1	1	affinity chromatography technology	Lu L (2013)	1
ANAPC15	0	CDC16	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
FZR1	1	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	HSPA2	3	affinity chromatography technology	Choudhury NR (2017)	1
CDK2	0	CDK6	0	biochemical, imaging technique	Cheng A (2000), Chen TC (2014)	2
CDK6	0	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	RRM2	2	genetic interference	Shen JP (2017)	1
FZR1	1	EPSTI1	0	two hybrid	Arroyo R (2015)	1
HECW2	13	CDC27	2	affinity chromatography technology	Lu L (2013)	1
RASSF1	3	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOX2	4	CDC23	3	affinity chromatography technology	Cox JL (2013)	1
MAP2K3	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNB1	3	PRKDC	12	affinity chromatography technology, pull down	Shang ZF (2015), Shang ZF (2015)	2
WEE1	2	CDC6	0	genetic interference	Srivas R (2016)	1
NF2	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	So J (2015), Lischetti T (2014)	2
BECN1	2	DDB1	6	affinity chromatography technology	Antonioli M (2014)	1
ANAPC4	0	CDC16	2	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Ma HT (2011), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Masuda K (2015), Boekhout M (2015), Huttlin EL (2017)	14
ARNT	1	TACC3	1	x-ray crystallography, pull down, biochemical	Guo Y (2015), Guo Y (2015), Guo Y (2015)	3
ANAPC13	0	ANAPC2	0	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC2	0	CDC23	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Hein MY (2015)	4
PLK1	0	FBXO5	2	affinity chromatography technology	Hansen DV (2004)	1
RASSF1	3	CUL1	7	affinity chromatography technology	Song MS (2008)	1
MYC	2	USP37	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Pan J (2014), Pan J (2014), Pan J (2014), Pan J (2014)	4
CCNE1	1	CDC25A	2	affinity chromatography technology, pull down	Shanahan F (1999), Xu X (1996)	2
FZR1	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC11	0	ANAPC2	0	pull down, pull down, two hybrid, biochemical, affinity chromatography technology	Tang Z (2001), Tang Z (2001), Ohta T (1999), Lu L (2013), Vodermaier HC (2003)	5
CCND1	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, pull down	Wei S (2008), Wei S (2008), Wei S (2008)	3
TP53	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	ANAPC2	0	affinity chromatography technology	Taipale M (2012)	1
UBE2S	2	UBE2D3	1	affinity chromatography technology	Kuang P (2016)	1
HSP90AA1	7	HSPA2	3	affinity chromatography technology	Gano JJ (2010)	1
STK11	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Zhou L (2015)	6
CUL1	7	EPSTI1	0	affinity chromatography technology	Bennett EJ (2010)	1
C16orf87	0	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
PLK1	0	GLB1	3	two hybrid	Vinayagam A (2011)	1
UBE2D3	1	TRIM25	5	two hybrid, pull down, pull down, affinity chromatography technology	Markson G (2009), Ronchi VP (2012), Choudhury NR (2017), Choudhury NR (2017)	4
DAXX	5	RASSF1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, unspecified method	Song MS (2008), Song MS (2008), Kitagawa D (2006), Kitagawa D (2006), Giovinazzi S (2012), Giovinazzi S (2012), Escobar-Cabrera E (2010), Zhang H (2013), Li Z (2017)	9
CCNB1	3	STAU1	1	affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015)	2
BECN1	2	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	ANAPC4	0	affinity chromatography technology, affinity chromatography technology	Song MS (2011), Song MS (2011)	2
FZR1	1	CKAP2	3	affinity chromatography technology, affinity chromatography technology	Hong KU (2007), Hong KU (2007)	2
MCPH1	4	CDC27	2	affinity chromatography technology, affinity chromatography technology, x-ray crystallography	Singh N (2012), Singh N (2012), Singh N (2012)	3
ANAPC5	2	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Sedgwick GG (2012)	2
SKP2	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), Zhang Q (2013), Kim TA (2013), Jamal A (2015), Fujii M (2006)	9
SOX4	5	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015), Hein MY (2015)	3
MAP3K5	1	DAXX	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Chang HY (1998), Chang HY (1998), Fukuyo Y (2009), Ko YG (2001), Ko YG (2001), Junn E (2005), Song JJ (2004), Charette SJ (2000), Chen TC (2014), Donath S (2016)	10
HIF1A	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	CDK4	2	affinity chromatography technology	Liu E (2004)	1
CDC20	1	PLK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Sedgwick GG (2012), Hyun SY (2013), Hyun SY (2013), Hyun SY (2013), Jia L (2016)	5
CKS1B	0	HSP90AA1	7	pull down	Radulovic M (2010)	1
HIF1A	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Amador V (2007), Horton LE (1997), Lin ML (2011), Lin ML (2011), OConnor PM (1993), Varjosalo M (2013), Kikuchi R (2014), Mateo F (2009), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	13
ANAPC2	0	GRIA1	5	affinity chromatography technology	Fu AK (2011)	1
PTTG1	0	BUB1B	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Kim HS (2009), Kim HS (2009), Kim HS (2009), Kim HS (2009), Horlbeck MA (2018)	5
CHEK2	2	FZR1	1	genetic interference	Srivas R (2016)	1
CCND2	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Moorthamer M (1999), Sweeney KJ (1997), Jiang W (1998), Welcker M (1998)	4
PRKDC	12	TP53	0	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim ST (1999), Goudelock DM (2003), Yavuzer U (1998), Maiti AK (2010), Shieh SY (1997), Chan DW (2000), Kim ST (1999), Sakaguchi K (1998), Borcherds W (2014)	9
USP37	1	CDC26	0	bioid	Yeh C (2015)	1
CHEK1	2	CDC6	0	genetic interference	Srivas R (2016)	1
LATS2	1	ANAPC1	1	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Zhu C (2018), Zhu C (2018), Zhu C (2018), Zhu C (2018)	6
TRIM33	4	BUB1B	0	affinity chromatography technology	Sedgwick GG (2012)	1
CDKN2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKB	2	RB1	2	pull down, enzymatic study, affinity chromatography technology	Nair JS (2009), Nair JS (2009), Nair JS (2009)	3
TRIM25	5	PLK1	0	affinity chromatography technology	Choudhury NR (2017)	1
TACC3	1	FZR1	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeng JC (2009), Jeng JC (2009), Jeng JC (2009), Jeng JC (2009), Ohoka N (2014)	5
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
SOX2	4	DNM1L	3	affinity chromatography technology	Cox JL (2013)	1
HECW2	13	CHEK1	2	affinity chromatography technology	Lu L (2013)	1
TP53	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOX2	4	TRIM33	4	affinity chromatography technology	Cox JL (2013)	1
BECN1	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Liu W (2011), Liu W (2011)	2
CCNA2	1	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTEN	24	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Song MS (2011), Song MS (2011), Song MS (2011), Song MS (2011)	4
ANAPC15	0	NEK2	2	affinity chromatography technology	Hein MY (2015)	1
CDC25A	2	MAP3K5	1	two hybrid, affinity chromatography technology, pull down	Zou X (2001), Zou X (2001), Zou X (2001)	3
CKS2	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
USP37	1	ANAPC1	1	bioid	Yeh C (2015)	1
NF2	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SENP2	3	MYC	2	enzymatic study	Gonzalez-Prieto R (2015)	1
CCND2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Sedgwick GG (2012)	2
CLSPN	1	PLK1	0	affinity chromatography technology, affinity chromatography technology	Peschiaroli A (2006), Mailand N (2006)	2
MDC1	8	CDC23	3	affinity chromatography technology	Woods NT (2012)	1
PAX3	6	DAXX	5	affinity chromatography technology	Hollenbach AD (1999)	1
CDC27	2	LNP1	1	affinity chromatography technology	Salsi V (2016)	1
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
CDK4	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NINL	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
MAP2K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	HOXD13	0	affinity chromatography technology	Salsi V (2016)	1
CDK1	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Major ML (2004)	2
TP53	0	CDC14B	1	affinity chromatography technology, pull down	Li L (2000), Li L (2000)	2
CDC20	1	STAU1	1	affinity chromatography technology, affinity chromatography technology	Boulay K (2014), Boulay K (2014)	2
FZR1	1	FMR1	1	affinity chromatography technology, affinity chromatography technology	Huang J (2015), Huang J (2015)	2
GLIS2	2	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	CLSPN	1	affinity chromatography technology	Gao D (2009)	1
SOX2	4	ANAPC5	2	affinity chromatography technology	Cox JL (2013)	1
FZR1	1	ARHGAP32	11	affinity chromatography technology, affinity chromatography technology	Kannan M (2012), Kannan M (2012)	2
CDC20	1	CDC23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016)	8
STK11	2	NAT2	0	two hybrid	Arroyo R (2015)	1
CCNF	2	CDC6	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Walter D (2016), Walter D (2016), Walter D (2016), Walter D (2016)	4
FZR1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhou Y (2003), Kramer ER (1998), Farhana L (2002), Cen B (2010), Sorensen CS (2001), Binne UK (2007), Wang X (2008), Tran K (2008), Wang LY (2012), Wang LY (2012), Ban KH (2007), Lv XB (2010), Huang KT (2012), Song MS (2011), Fukushima H (2013), Lau AW (2013), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Choi BH (2014), Jeganathan KB (2006), Fang G (1998), Sedgwick GG (2012), Kelly A (2014), Listovsky T (2013), Pavlides SC (2016), Huttlin EL (2017)	28
CDK6	0	TPX2	4	enzymatic study	Anders L (2011)	1
MET	7	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	PDGFRA	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	CCNE1	1	affinity chromatography technology	Liu E (2004)	1
GLIS2	2	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KMT5A	2	DDB1	6	affinity chromatography technology	Abbas T (2010)	1
HECW2	13	ANAPC4	0	affinity chromatography technology	Lu L (2013)	1
CHEK2	2	CDC6	0	genetic interference	Srivas R (2016)	1
FZR1	1	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	ANAPC10	0	affinity chromatography technology	Boekhout M (2015)	1
TTK	4	CDC16	2	affinity chromatography technology	Liu ST (2003)	1
MAP2K5	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
TTK	4	TP53	0	affinity chromatography technology, pull down, enzymatic study	Huang YF (2009), Huang YF (2009), Huang YF (2009)	3
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
BECN1	2	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
FZR1	1	NEDD9	3	affinity chromatography technology, pull down, pull down	Nourry C (2004), Nourry C (2004), Ice RJ (2013)	3
NINL	1	TTK	4	bioid	Gupta GD (2015)	1
MYC	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	RNF157	3	affinity chromatography technology	Dogan T (2017)	1
UBE2S	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, pull down	Williamson A (2009), Williamson A (2009), Williamson A (2009), Williamson A (2009), Williamson A (2009), Wang W (2013), Brown NG (2014), Kelly A (2014)	8
DAXX	5	FZR1	1	affinity chromatography technology	Kwan PS (2013)	1
AURKA	1	HSPA2	3	affinity chromatography technology	Fogeron ML (2013)	1
RNF34	1	CDC20	1	affinity chromatography technology	Puliyappadamba VT (2011)	1
DAXX	5	CDC20	1	affinity chromatography technology	Kwan PS (2013)	1
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
PRKDC	12	MAPK8	3	enzymatic study	Park SJ (2001)	1
CHEK2	2	CYP17A1	5	two hybrid	Arroyo R (2015)	1
CDK1	0	CKS2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Varjosalo M (2013), Radulovic M (2010), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
BECN1	2	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK8	3	AKT1	1	enzymatic study	Xiao L (2010)	1
NF2	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	PRKDC	12	genetic interference	Shen JP (2017)	1
EYA1	4	SIX1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Buller C (2001), Buller C (2001), Huttlin EL (2015), Huttlin EL (2017)	4
ANAPC7	2	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
CDK2	0	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
TP53	0	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC11	0	PTTG1	0	enzymatic study, enzymatic study, enzymatic study	Gmachl M (2000), Tang Z (2001), Vodermaier HC (2003)	3
ANAPC4	0	FZR1	1	biochemical, biochemical, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Boekhout M (2015), Huttlin EL (2017)	6
CCNA2	1	CDC27	2	affinity chromatography technology	Mateo F (2009)	1
PRKN	1	NEK2	2	affinity chromatography technology, enzymatic study	Lee SB (2015), Lee SB (2015)	2
SOX2	4	MTA3	3	affinity chromatography technology	Cox JL (2013)	1
PTEN	24	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM33	4	CCNA2	1	affinity chromatography technology	Sedgwick GG (2012)	1
FZR1	1	PDGFRA	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	CDC26	0	affinity chromatography technology	Zhu C (2018)	1
FBXO5	2	ANAPC2	0	pull down	Miller JJ (2006)	1
DDB1	6	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
FZR1	1	MAPK8	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Gutierrez GJ (2010), Gutierrez GJ (2010), Gutierrez GJ (2010)	3
PTEN	24	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
E2F1	0	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Budhavarapu VN (2012), Nath S (2014)	2
CDK4	2	CDKN2B	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Rual JF (2005), Stelzl U (2005), Vinayagam A (2011), Xin X (2009), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Ivanov AA (2017)	12
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
VHL	0	AURKA	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Martin B (2013), Martin B (2013), Hasanov E (2017), Hasanov E (2017), Hasanov E (2017)	5
TP53	0	HECW2	13	affinity chromatography technology	Miyazaki K (2003)	1
PRKDC	12	CHEK1	2	unspecified method, pull down, genetic interference	Kim ST (1999), Goudelock DM (2003), Shen JP (2017)	3
FZR1	1	ANAPC11	0	affinity chromatography technology, pull down, unspecified method	Bassermann F (2008), Vodermaier HC (2003), Vodermaier HC (2003)	3
MAP2K5	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRP68	2	FZR1	1	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC2	0	CDC16	2	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
TRIM25	5	WEE1	2	affinity chromatography technology	Choudhury NR (2017)	1
CDK4	2	FOXM1	3	enzymatic study	Anders L (2011)	1
FZR1	1	GLB1	3	affinity chromatography technology	Huttlin EL (2017)	1
FGFR4	6	BLID	0	two hybrid	Arroyo R (2015)	1
NF2	1	CDK5	0	affinity chromatography technology	Zhou L (2015)	1
PTEN	24	AKT1	1	affinity chromatography technology, fluorescent resonance energy transfe	Mistafa O (2010), Ivanov AA (2017)	2
TP53	0	STK11	2	affinity chromatography technology, fluorescent resonance energy transfe	Karuman P (2001), Ivanov AA (2017)	2
RASSF1	3	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS1B	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
AKT1	1	CHEK1	2	genetic interference	Shen JP (2017)	1
MAP2K5	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	FBXO5	2	affinity chromatography technology	Reitsma JM (2017)	1
LATS2	1	ANAPC5	2	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Zhu C (2018), Zhu C (2018)	4
HECW2	13	CCNA1	3	affinity chromatography technology	Lu L (2013)	1
TRIM25	5	AKT1S1	1	affinity chromatography technology	Choudhury NR (2017)	1
ANAPC4	0	CDK1	0	affinity chromatography technology	Voets E (2015)	1
TAS2R13	2	FZR1	1	affinity chromatography technology	Ohoka N (2010)	1
HECW2	13	CDT1	2	affinity chromatography technology	Lu L (2013)	1
MYC	2	PRKDC	12	affinity chromatography technology, genetic interference	Koch HB (2007), Zhou Z (2014)	2
TP53	0	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	CLSPN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Peschiaroli A (2006), Mailand N (2006), Peschiaroli A (2006), Gao D (2009), Bassermann F (2008), Kee Y (2009)	6
KMT5A	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang Z (2015), Wang Z (2015), Wang Z (2015), Wang Z (2015), Wang Z (2015)	5
MYC	2	WEE1	2	genetic interference	Toyoshima M (2012)	1
CDK4	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	FZR1	1	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
CKS1B	0	CDC27	2	pull down	Di Fiore B (2010)	1
HSP90AA1	7	CDK6	0	affinity chromatography technology	Taipale M (2012)	1
ARHGAP32	11	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Kannan M (2012), Kannan M (2012)	2
MAP3K5	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARNT	1	MTA3	3	two hybrid	Wang J (2011)	1
MAP2K5	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	FZR1	1	affinity chromatography technology	Choudhury NR (2017)	1
TK1	0	CDC20	1	pull down	Ke PY (2004)	1
MOAP1	0	DDB1	6	affinity chromatography technology	Matsuura K (2016)	1
PDGFRA	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	PLK1	0	affinity chromatography technology, enzymatic study	Li Z (2014), Li Z (2014)	2
SOX2	4	ANAPC2	0	affinity chromatography technology	Cox JL (2013)	1
FZR1	1	HSPA2	3	affinity chromatography technology	Huttlin EL (2017)	1
CDK4	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	PHF8	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2K	0	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay	Bae Y (2013), Bae Y (2013), Bae Y (2013)	3
GMNN	0	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
GLS	3	FZR1	1	affinity chromatography technology	Zhao J (2017)	1
NF2	1	IST1	0	affinity chromatography technology	Zhou L (2015)	1
PRKN	1	AURKA	1	affinity chromatography technology	Lee SB (2015)	1
CDC6	0	CDC20	1	pull down	Ke PY (2004)	1
CDT1	2	ANAPC5	2	affinity chromatography technology	Sugimoto N (2008)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
SMURF1	4	TP53	0	affinity chromatography technology	Nie J (2010)	1
CDK4	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nair JS (2009), Takaki T (2004), Deep G (2006), Kehn K (2004), Scholz A (2003), Gladden AB (2003), Mori S (1999), Higashi H (1996), Musgrove EA (1996), Sarmento LM (2005), Kim KS (2002), Li J (2002), Garcia-Morales P (2006), Tsai CH (2009), Miralem T (2003), Toji S (2004), Halder SK (2005), Dynlacht BD (1997), Mandal M (1998), Voit R (1999), Annicotte JS (2006), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Kitagawa M (1996), Anders L (2011), Gaiddon C (2003), Seo DW (2006), Kabuta T (2013), Lee B (2006), Kossatz U (2006), Zarkowska T (1997), Nakanishi M (1999), Iyer NG (2007), Guidoboni M (2005), Barbash O (2009), Wang C (2001), Denicourt C (2008), Pan W (2001)	39
CCNE1	1	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Luescher-Firzlaff JM (2006)	2
CDC20	1	CDC26	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Masuda K (2015), Kelly A (2014), Craney A (2016)	4
FZR1	1	BLID	0	two hybrid	Arroyo R (2015)	1
VHL	0	EPHA4	3	affinity chromatography technology	Lai Y (2011)	1
KAT2A	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	NAT2	0	two hybrid	Arroyo R (2015)	1
MAP2K5	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	FZR1	1	affinity chromatography technology, affinity chromatography technology	Fukushima H (2013), Fukushima H (2013)	2
ANAPC10	0	HHEX	1	affinity chromatography technology	Salsi V (2016)	1
CDKN2A	1	DAXX	5	pull down, affinity chromatography technology, affinity chromatography technology	Ivanchuk SM (2008), Ivanchuk SM (2008), Ivanchuk SM (2008)	3
DDB1	6	KAT2A	1	affinity chromatography technology, pull down, affinity chromatography technology	Martinez E (2001), Martinez E (2001), Li Y (2011)	3
CCND2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC11	0	CDC16	2	biochemical	Lu L (2013)	1
CKS1B	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
RASSF1	3	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC25A	2	CCNA2	1	affinity chromatography technology	Li X (2016)	1
ARNT	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MET	7	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	FANCD2	3	enzymatic study, genetic interference	Zhi G (2009), Pichierri P (2004)	2
IST1	0	FZR1	1	affinity chromatography technology	Zhang X (2011)	1
CKS2	0	HSP90AA1	7	pull down	Radulovic M (2010)	1
BUB1B	0	CCNA2	1	pull down	Di Fiore B (2015)	1
CCNA1	3	CDC25A	2	affinity chromatography technology, affinity chromatography technology	Liu D (2000), Li X (2016)	2
CDKN2B	0	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	CDC25A	2	pull down, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Goloudina A (2003), Sanchez Y (1997), Sanchez Y (1997), Zhao H (2002), Jin J (2008), Hassepass I (2003), Sorensen CS (2003), Li X (2016)	8
MAP2K5	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAD2L2	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical	Iwai H (2007), Chen J (2001), Chen J (2001), Listovsky T (2013), Listovsky T (2013), Listovsky T (2013), Listovsky T (2013), Listovsky T (2013)	8
FZR1	1	NUP98	5	affinity chromatography technology	Salsi V (2016)	1
FZR1	1	ANAPC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Stewart S (2005), Wen H (2010), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Huttlin EL (2017)	6
FZR1	1	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
MAP2K5	1	TP53	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CCNA1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sorensen CS (2001), Sorensen CS (2001), Gao D (2009), Fukushima H (2013)	4
CDC20	1	RASSF1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chow C (2011), Chow C (2011), Wang X (2008), Song MS (2004)	4
SOX4	5	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
VHL	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, far western blotting, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, protein complementation assay, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Corn PG (2003), Li Z (2003), Mahon PC (2001), Tanimoto K (2000), Min JH (2002), Yu F (2001), Yu F (2001), Jung JE (2008), Jung JE (2008), Andre H (2008), Park YK (2008), Kim BY (2008), Park SS (2008), Baek JH (2007), Baek JH (2007), Baek JH (2007), Kondo S (2006), Ietta F (2006), Kwon SJ (2005), Bae MK (2005), Baek JH (2005), Hon WC (2002), Hon WC (2002), Lewis MD (2004), Kasuno K (2004), Metzen E (2003), Metzen E (2003), Zhou J (2003), Yuan Y (2003), Maynard MA (2003), Jeong JW (2002), Yoo YG (2008), Hansen WJ (2002), Masson N (2001), Masson N (2001), Clifford SC (2001), Jaakkola P (2001), Jaakkola P (2001), Kamura T (2000), Kamura T (2000), Kamura T (2000), Ohh M (2000), Ohh M (2000), Cockman ME (2000), Cockman ME (2000), Sufan RI (2006), Chang CC (2011), Sufan RI (2009), Stickle NH (2004), Luo W (2010), Lee HY (2011), Roe JS (2011), Ivan M (2001), Ivan M (2001), Huang LE (2002), Callapina M (2005), Callapina M (2005), Maranchie JK (2002), DAngelo G (2003), DAngelo G (2003), Miller F (2005), Grosfeld A (2007), Grosfeld A (2007), Rajakumar A (2008), Bonicalzi ME (2001), Bemis L (2004), Berra E (2001), Yu F (2001), Bex C (2007), Zhou J (2012), Wiesener MS (2002), Maxwell PH (1999), Maxwell PH (1999), Lee SH (2012), Lee SH (2012), Ivan M (2002), Aprelikova O (2009), Choi CY (2009), Choi CY (2009), Heir P (2013), Russell RC (2008), Russell RC (2008), Park JH (2011), Park JH (2011), Liu Q (2013), Yeh IJ (2013), Choi YK (2010), Yang F (2014), Yang F (2014), Yang F (2014), Parsanejad M (2014), Yang C (2013), Yang C (2013), Chen K (2013), Park MH (2014), Gerez J (2015), Hein MY (2015), Park MH (2015), Fu R (2016), Alahari S (2015), Zhang CS (2015), Song D (2013), Chen K (2016), Hicks KC (2016), Groulx I (2002), Groulx I (2002), Groulx I (2002), Huttlin EL (2017), Guo J (2016), Sun W (2017), Sun W (2017), Guo J (2016), Li YM (2005), Yoo YG (2004), Kimura M (2008), Ferrer CM (2014)	116
LATS2	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOX2	4	CDC26	0	affinity chromatography technology	Cox JL (2013)	1
CDT1	2	CDC20	1	pull down	Sugimoto N (2008)	1
CDC14A	4	CKAP2	3	bioid	St-Denis N (2016)	1
CDC27	2	DCPS	1	two hybrid	Wang J (2011)	1
CCND1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology	Pawar SA (2010), Pawar SA (2010)	2
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
UBE2S	2	CDC23	3	affinity chromatography technology, pull down, pull down	Wang W (2013), Brown NG (2014), Kelly A (2014)	3
AURKA	1	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
AURKA	1	TPX2	4	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kufer TA (2002), Kufer TA (2002), Katayama H (2008), Trieselmann N (2003), Hutchins JR (2010), Maxwell CA (2011), Maxwell CA (2011), Fu J (2009), Huttlin EL (2015), Huttlin EL (2017), Ertych N (2016)	11
CDC25A	2	CDK2	0	pull down, enzymatic study, affinity chromatography technology	Xu X (1996), Cheng A (2005), Li X (2016)	3
CDKN2A	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDCA3	0	WEE1	2	pull down	Ayad NG (2003)	1
CDC27	2	CDC16	2	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Ollendorff V (1997), Kallio M (1998), Gmachl M (2000), Kraft C (2003), Li Y (1997), Lara-Gonzalez P (2011), Binne UK (2007), van Zon W (2010), Dube P (2005), Holzmann J (2011), Hayes MJ (2006), Tugendreich S (1995), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Kelly A (2014), Listovsky T (2013), Qiao R (2016), Huttlin EL (2017), Boldt K (2016)	22
E2F3	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inoue Y (2007), Moberg K (1996), Ianari A (2009), Lees JA (1993)	4
SMURF1	4	PDGFRA	3	enzymatic study	Andrews PS (2010)	1
SOX4	5	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	THRSP	0	two hybrid	Arroyo R (2015)	1
CDK6	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Garcia-Morales P (2006), Aprelikova O (1995), Yarbrough WG (1999), Dynlacht BD (1997), Jiang W (1998), Anders L (2011), Nakanishi M (1999), Iyer NG (2007)	8
EPHA2	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STAU1	1	PRKDC	12	affinity chromatography technology	Milev MP (2012)	1
CDKN2B	0	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	CKS1B	0	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Radulovic M (2010), Huttlin EL (2017)	3
FZR1	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Luescher-Firzlaff JM (2006)	2
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
PHF8	6	FZR1	1	affinity chromatography technology	Lim HJ (2013)	1
LATS2	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSP90AA1	7	BECN1	2	affinity chromatography technology	Xu C (2011)	1
KMT5A	2	TP53	0	enzymatic study	Shi X (2007)	1
SOX4	5	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARNT	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
ANAPC4	0	CDC23	3	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015)	8
ARNT	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	UBE2S	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Choudhury NR (2017)	2
CDK5	0	CCNB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	5
CDK1	0	E2F1	0	enzymatic study	Dynlacht BD (1997)	1
CKS2	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
USP37	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, bioid, affinity chromatography technology	Burrows AC (2012), Burrows AC (2012), Burrows AC (2012), Saxena N (2014), Yeh C (2015), Huttlin EL (2017)	6
AURKA	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	RBBP8	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fusco C (1998), Fusco C (1998), Liu F (2006)	4
RASSF1	3	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIM1	2	FZR1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Cen B (2010), Cen B (2010)	3
CCND1	1	RB1	2	pull down, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Siegert JL (2000), Siegert JL (2000), Dowdy SF (1993), Chan HM (2001), Dasgupta P (2004), Dasgupta P (2004), Sweeney KJ (1997), Higashi H (1996), Musgrove EA (1996), Yarbrough WG (1999), Connell-Crowley L (1997), Kitagawa M (1996), Poon RY (1996), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999), Welcker M (1998)	17
ERBB2	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	ANAPC2	0	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC27	2	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Mansfeld J (2011), Lara-Gonzalez P (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Ma HT (2011), Ma HT (2011), Dube P (2005), Holzmann J (2011), Wolthuis R (2008), Havugimana PC (2012), Uzunova K (2012), Song MS (2011), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Tran K (2010), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Voets E (2015), Masuda K (2015), Boekhout M (2015), Craney A (2016), Qiao R (2016), Izawa D (2012), Hein JB (2016)	34
CCNE1	1	CDK1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Koff A (1992), Koff A (1992), Horton LE (1997)	4
CDKN2A	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KAT2A	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	CHEK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu S (2009), Huh J (2013), Zhang YW (2005)	3
AKT1	1	CCNF	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Choudhury R (2017), Choudhury R (2017), Choudhury R (2017)	3
ANAPC13	0	CDC23	3	biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference	Havugimana PC (2012), Rolland T (2014), Hein MY (2015), Huttlin EL (2017), Horlbeck MA (2018)	5
NINL	1	CKAP2	3	bioid	Gupta GD (2015)	1
CDC27	2	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Tran K (2008), Dube P (2005), Holzmann J (2011), Havugimana PC (2012), Sedgwick GG (2012), Song MS (2011), Vodermaier HC (2003), Tran K (2010), Yamaguchi M (2015), Yamaguchi M (2015), Wan C (2015), Kelly A (2014), Craney A (2016), Qiao R (2016), Boldt K (2016)	19
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
ANAPC10	0	CDC16	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Kurasawa Y (1999), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	4
CDK5	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
MDC1	8	ANAPC10	0	affinity chromatography technology	Woods NT (2012)	1
PLK1	0	CHEK2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Tsvetkov L (2003), Tsvetkov L (2003), Tsvetkov L (2003), van Vugt MA (2010)	4
BECN1	2	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	HSF2	2	pull down, affinity chromatography technology	Ahlskog JK (2010), Ahlskog JK (2010)	2
SOX4	5	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	MAPK8	3	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Choi BY (2005), Choi BY (2005), Choi BY (2005), Choi BY (2005)	4
CDK6	0	CDC6	0	enzymatic study	Anders L (2011)	1
E2F1	0	KAT2A	1	affinity chromatography technology	Lang SE (2001)	1
PRKN	1	CDK5	0	affinity chromatography technology, enzymatic study	Avraham E (2007), Avraham E (2007)	2
CDK4	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	PLK1	0	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Izumi H (2009), Izumi H (2009), Izumi H (2009), Matsumura S (2007), Matsumura S (2007), Matsumura S (2007), Matsumura S (2007), Beck J (2013), Metzger T (2013), Zhuo X (2015)	10
CDK6	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	HIF1A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang J (2012), Cataldo F (2013), Maestre C (2008), Maestre C (2008)	4
ARNT	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Song MS (2011), Song MS (2011)	2
HIF1A	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	ANAPC5	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Sedgwick GG (2012), Huttlin EL (2017)	3
GLIS2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	RBBP8	1	affinity chromatography technology, pull down	Lafranchi L (2014), Lafranchi L (2014)	2
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
CCNA1	3	SKP2	2	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji P (2006), Ji P (2006), Ji P (2006), Yam CH (2000), Gao D (2009), Ji P (2007)	6
VHL	0	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology	Ji W (2014), Ji W (2014), Ji W (2014)	3
MAPK8	3	NUP98	5	affinity chromatography technology	So J (2015)	1
MDC1	8	TP53	0	affinity chromatography technology	Xu X (2003)	1
TEAD2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	MCPH1	4	affinity chromatography technology, affinity chromatography technology	Liu X (2017), Liu X (2017)	2
RASSF1	3	ID1	0	affinity chromatography technology	Wang X (2008)	1
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
ANAPC1	1	ANAPC4	0	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Sumara I (2000), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015)	9
TTK	4	CDK2	0	enzymatic study	Nekhai S (1997)	1
CDCA3	0	FZR1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RB1	2	ARNT	1	affinity chromatography technology	Ge NL (1998)	1
E2F1	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Budhavarapu VN (2012), Budhavarapu VN (2012), Budhavarapu VN (2012), Singh RK (2017)	4
ZC3HC1	1	CCNB1	3	pull down, affinity chromatography technology, enzymatic study, enzymatic study	Bassermann F (2007), Bassermann F (2005), Bassermann F (2005), Liu YQ (2015)	4
SOX4	5	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	CDK1	0	affinity chromatography technology	Choudhury NR (2017)	1
BRSK2	5	WEE1	2	enzymatic study	Lu R (2004)	1
FZR1	1	FOXM1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park HJ (2008), Myatt SS (2013), Laoukili J (2008), Laoukili J (2008)	4
MYC	2	CDK2	0	genetic interference, genetic interference	Toyoshima M (2012), Zhou Z (2014)	2
ID1	0	FZR1	1	affinity chromatography technology, affinity chromatography technology	Wang X (2008), Wang X (2008)	2
CDK6	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Sweeney KJ (1997), Varjosalo M (2013), Ivanov AA (2017)	4
CDC27	2	NEK2	2	affinity chromatography technology, affinity chromatography technology	Hayes MJ (2006), Boekhout M (2015)	2
KAT2A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CCL5	1	two hybrid	Arroyo R (2015)	1
PRKDC	12	AKT1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Feng J (2004), Feng J (2004), Feng J (2004), Dragoi AM (2005), Dragoi AM (2005), Dragoi AM (2005), Shen JP (2017)	7
ARNT	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	CLSPN	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Chini CC (2003), Chini CC (2003), Chini CC (2006), Chini CC (2006), Chini CC (2006), Huh J (2013), Clarke CA (2005), Clarke CA (2005)	8
STK11	2	TRIM25	5	two hybrid	Arroyo R (2015)	1
KAT2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTTG1	0	CUL1	7	affinity chromatography technology, pull down	Molina-Jimenez F (2010), Molina-Jimenez F (2010)	2
CDC27	2	ANAPC11	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Dube P (2005), Lu L (2013), Gmachl M (2000), Vodermaier HC (2003), Craney A (2016)	8
LATS2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	PTTG1	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Bernal JA (2002), Bernal JA (2002), Bernal JA (2002), Kim HS (2009)	4
ARNT	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNF	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Choudhury R (2016), Choudhury R (2016), Choudhury R (2016)	3
ERBB2	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK8	3	HSP90AA1	7	affinity chromatography technology	Nieto-Miguel T (2008)	1
DAXX	5	TERT	7	affinity chromatography technology	Tang M (2015)	1
MAP2K3	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA2	3	FANCD2	3	affinity chromatography technology	Hein MY (2015)	1
CDKN2A	1	NAT2	0	two hybrid	Arroyo R (2015)	1
CDK1	0	CHEK1	2	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	ANAPC1	1	affinity chromatography technology	Choudhury NR (2017)	1
PRKN	1	UBE2C	1	pull down	Kazlauskaite A (2014)	1
TP53	0	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	4
GLIS2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	PTTG1	0	enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Braunstein I (2007), Eytan E (2006), Pfleger CM (2001), Kim HS (2009), Kwan PS (2013), Tian W (2012), Van Voorhis VA (2014), Lara-Gonzalez P (2011), Wu T (2010), Izawa D (2014), Hellmuth S (2014), Wu T (2010), Shoji S (2014), Lara-Gonzalez P (2011), Di Fiore B (2015), Lee SB (2015), Qiao R (2016), Alfieri C (2016), Izawa D (2012), Jia L (2016)	20
BUB1B	0	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Sedgwick GG (2012), Sedgwick GG (2016)	4
CDC25A	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2003), Donzelli M (2004), Busino L (2003), Donzelli M (2002), He N (2005), Li X (2016)	6
MYC	2	NEK2	2	genetic interference	Toyoshima M (2012)	1
TP53	0	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC5	2	ANAPC7	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Sedgwick GG (2012)	2
CDC16	2	NEK2	2	affinity chromatography technology	Hein MY (2015)	1
CCNA2	1	CKS2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Huttlin EL (2017)	4
CDC20	1	HOXD13	0	affinity chromatography technology	Salsi V (2016)	1
ARNT	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	SMURF1	4	pull down, affinity chromatography technology, affinity chromatography technology	Lee MG (2016), Lee MG (2016), Lee MG (2016)	3
FZR1	1	DKK3	3	two hybrid	Arroyo R (2015)	1
ARNT	1	HIF1A	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, two hybrid, imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, two hybrid, two hybrid	Woods SL (2002), Hogenesch JB (1997), Hogenesch JB (1997), Behrends C (2010), Wang F (2004), Lim W (2011), Sufan RI (2009), Sufan RI (2009), Katschinski DM (2004), Katschinski DM (2004), Chun YS (2002), Hein MY (2015), Huttlin EL (2017), Kalousi A (2010), Kalousi A (2010), Isaacs JS (2004), Chilov D (1999), Chilov D (1999), Chilov D (1999), Kallio PJ (1997), Amir S (2009), Yang L (2008), Hur E (2002), Lando D (2000), Sadek CM (2000), Chapman-Smith A (2006), Suzuki H (2001), Suzuki H (2001), Li YM (2005), Jiang BH (1996), Jiang BH (1996), Jiang BH (1996), Jiang BH (1996), Park EJ (2006), Park EJ (2006), Ruas JL (2005), Wotzlaw C (2007), Ivanov AA (2017), Depping R (2004), Depping R (2004), Depping R (2004)	41
UBE2C	1	BUB1B	0	biochemical	Reddy SK (2007)	1
SIX1	3	FZR1	1	affinity chromatography technology	Christensen KL (2007)	1
CCNB1	3	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Zon W (2010), Izawa D (2011), Voets E (2015), Voets E (2015)	4
RB1	2	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
PTEN	24	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	PTEN	24	genetic interference	Shen JP (2017)	1
HSP90AA1	7	TERT	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Holt SE (1999), Lee JH (2010), Lee JH (2010), Forsythe HL (2001)	6
MDC1	8	FZR1	1	affinity chromatography technology	Woods NT (2012)	1
C16orf87	0	CDC16	2	affinity chromatography technology	Huttlin EL (2017)	1
CCNA1	3	CDK1	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sweeney C (1996), Lukas J (1992), Desai D (1995), Rohaly G (2005)	4
PTEN	24	HSPA2	3	affinity chromatography technology	Maddika S (2011)	1
CUL1	7	STAU1	1	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	CDR2	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	ODonovan KJ (2010), Okano HJ (1999), Okano HJ (1999), Okano HJ (1999), Okano HJ (1999)	5
AURKA	1	TACC3	1	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology	Tien AC (2004), Tien AC (2004), Huttlin EL (2015), Huttlin EL (2017)	4
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
HECW2	13	CDC20	1	affinity chromatography technology	Lu L (2013)	1
AKT1	1	FANCD2	3	affinity chromatography technology	Zhang X (2016)	1
GLIS2	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDC1	8	CHEK2	2	affinity chromatography technology, pull down	Lou Z (2003), Lou Z (2003)	2
MET	7	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
CCND1	1	CDK2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sweeney KJ (1997), Higashi H (1996), Higashi H (1996), Varjosalo M (2013), Hein MY (2015), Huttlin EL (2017)	6
PDGFRA	3	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	ANAPC7	2	unspecified method, affinity chromatography technology	Vodermaier HC (2003), Sedgwick GG (2012)	2
NF2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	ANAPC7	2	affinity chromatography technology, affinity chromatography technology	Song MS (2011), Song MS (2011)	2
CDKN2A	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lee SB (2015), Lee SB (2015), Lee SB (2015)	3
ANAPC4	0	ANAPC15	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Uzunova K (2012), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Chang L (2015), Yamaguchi M (2015), Hein MY (2015)	8
GLIS2	2	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
USP37	1	ANAPC13	0	bioid	Yeh C (2015)	1
DDB1	6	TERT	7	affinity chromatography technology	Jung HY (2013)	1
MYC	2	FANCD2	3	affinity chromatography technology, imaging technique	Koch HB (2007), Panneerselvam J (2014)	2
NF2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PDGFRA	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARNT	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	PTEN	24	genetic interference	Shen JP (2017)	1
CDK4	2	ERBB2	6	genetic interference, fluorescent resonance energy transfe	Shen JP (2017), Ivanov AA (2017)	2
FZR1	1	NAT2	0	two hybrid	Arroyo R (2015)	1
AKT1	1	NF2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Tang X (2007), Tang X (2007), Tang X (2007), Tang X (2007), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Ivanov AA (2017)	9
E2F1	0	DDB1	6	affinity chromatography technology	Hayes S (1998)	1
HIF1A	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
VHL	0	CDK2	0	affinity chromatography technology	Ewing RM (2007)	1
CDT1	2	CDC23	3	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
CCNE1	1	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
MYC	2	BTRC	1	affinity chromatography technology, enzymatic study	Popov N (2010), Popov N (2010)	2
CHEK1	2	VHL	0	genetic interference	Shen JP (2017)	1
BTRC	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Xia Y (2009), Verma S (2011)	2
FBXO5	2	FZR1	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hsu JY (2002), Hsu JY (2002), Reimann JD (2001), Miller JJ (2006), Huttlin EL (2017)	5
EPHA2	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	PLK1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lee SB (2015), Lee SB (2015), Lee SB (2015)	3
MAP2K5	1	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOX2	4	ANAPC7	2	affinity chromatography technology	Cox JL (2013)	1
ANAPC11	0	CCNB1	3	pull down	Frye JJ (2013)	1
FBXO5	2	ANAPC1	1	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
CDKN2A	1	CDK6	0	unspecified method, x-ray crystallography, pull down, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Fahraeus R (1996), Russo AA (1998), Kaldis P (2001), Yarbrough WG (1999), Della Torre G (2001), Ezhevsky SA (1997), Ezhevsky SA (1997), Jones R (2007), Jones R (2007), Ramachandran N (2004), Varjosalo M (2013), Souza-Rodrigues E (2007), Huttlin EL (2015), Huttlin EL (2017), Ivanov AA (2017)	15
RB1	2	MYC	2	two hybrid, fluorescent resonance energy transfe	Adnane J (1995), Ivanov AA (2017)	2
CHEK1	2	WEE1	2	genetic interference, genetic interference	Srivas R (2016), Srivas R (2016)	2
BECN1	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDC1	8	ANAPC4	0	affinity chromatography technology	Woods NT (2012)	1
CDKN2A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Roe JS (2011), Roe JS (2011), Roe JS (2011)	3
UBE2D3	1	STAU1	1	two hybrid	Vinayagam A (2011)	1
HSP90AA1	7	EPHA2	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
PRKN	1	HSPA2	3	affinity chromatography technology	Zanon A (2013)	1
FZR1	1	UBE2C	1	pull down, pull down, enzymatic study	Jin L (2008), Williamson A (2009), Williamson A (2011)	3
CDK6	0	CDKN2B	0	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Mo XL (2015), Huttlin EL (2017), Ivanov AA (2017)	8
NF2	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC11	0	UBE2C	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Wu T (2010), Ke PY (2007), Jia L (2011), Braunstein I (2007), van Zon W (2010), Eytan E (2006), Ping Z (2012), Townsend K (2009), Huang NJ (2012), Chow C (2011), Zhang Z (2012), Bassermann F (2008), Wang W (2013), Frye JJ (2013), Han JS (2013), Chang L (2014), Lara-Gonzalez P (2011), He J (2013), Lau AW (2013), Han JS (2014), Sedgwick GG (2013), von Klitzing C (2011), Tang Z (2001), Shoji S (2014), Fukushima H (2013), Yamaguchi M (2015), Sajman J (2015), Brown NG (2015), Brown NG (2014), Cao J (2015), Zhang S (2016), Williamson A (2011), Qiao R (2016), Alfieri C (2016), Brown NG (2016), Li Q (2016), Izawa D (2012)	37
GLIS2	2	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MCPH1	4	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang SZ (2008), Yang SZ (2008), Aoki I (2012)	3
VHL	0	UBE2D1	0	pull down	Gao C (2010)	1
AKT1	1	USP1	4	affinity chromatography technology	Zhang X (2016)	1
USP37	1	CCNA2	1	affinity chromatography technology, enzymatic study	Huang X (2011), Huang X (2011)	2
CUL1	7	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015)	2
CDC20	1	ANAPC11	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study	Nilsson J (2008), Chen TC (2014), Lee SB (2015), Alfieri C (2016)	4
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
MAPK8	3	MYC	2	enzymatic study, pull down, affinity chromatography technology	Noguchi K (1999), Noguchi K (1999), Noguchi K (1999)	3
ERBB2	6	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	AURKA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, genetic interference, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Katayama H (2004), Katayama H (2004), Katayama H (2004), Katayama H (2004), Hsueh KW (2013), Huttlin EL (2015), Huttlin EL (2017)	12
BTRC	1	CDC25A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Ray D (2005), Jin J (2003), Jin J (2003), Honaker Y (2010), Honaker Y (2010), Gao D (2009), Donzelli M (2004), Donzelli M (2004), Jin J (2005), Busino L (2003), Busino L (2003), Busino L (2003), Busino L (2003), Kim TY (2014), Jin J (2003), Coyaud E (2015), Loveless TB (2015), Coyaud E (2015), He N (2005), He N (2005), St-Denis N (2016), Huttlin EL (2017)	23
E2F1	0	CDK2	0	pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu M (1994), Dynlacht BD (1997), Dynlacht BD (1997), Ohta T (2001)	4
USP37	1	ANAPC4	0	bioid	Yeh C (2015)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
SOX4	5	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CDR2	1	enzymatic study	ODonovan KJ (2010)	1
PHF8	6	ANAPC5	2	affinity chromatography technology	Lim HJ (2013)	1
UBE2C	1	CKAP2	3	enzymatic study	Hong KU (2007)	1
CKS1B	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jackman M (2002), Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
PDGFRA	3	RRM2	2	genetic interference	Shen JP (2017)	1
CDC14B	1	AURKB	2	bioid	St-Denis N (2016)	1
GLIS2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO5	2	ANAPC7	2	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
SPRTN	0	STAU1	1	affinity chromatography technology	Kim MS (2013)	1
SMURF1	4	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Cui Y (2011), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017)	5
DDB1	6	BTRC	1	affinity chromatography technology	He YJ (2006)	1
MYC	2	HIF1A	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Koshiji M (2004), Koshiji M (2004), Ivanov AA (2017)	3
SMURF1	4	UBE2D3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Nie J (2010), Nie J (2010), Fei C (2013), Wang J (2013), Cao Y (2014), Xie P (2014), Xie P (2014), Lu K (2008), Kristariyanto YA (2015), Andrews PS (2010), He S (2017), Zhang Y (2017)	12
WEE1	2	FZR1	1	genetic interference	Srivas R (2016)	1
UBE2S	2	SRP68	2	affinity chromatography technology	Hu L (2017)	1
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
CUL1	7	AKT1	1	affinity chromatography technology	Reitsma JM (2017)	1
STAU1	1	CDK1	0	affinity chromatography technology	Milev MP (2012)	1
TRIM25	5	BTRC	1	affinity chromatography technology	Choudhury NR (2017)	1
UBE2S	2	ANAPC2	0	affinity chromatography technology, pull down, pull down, pull down	Wang W (2013), Brown NG (2014), Brown NG (2014), Kelly A (2014)	4
RNF34	1	FZR1	1	affinity chromatography technology, affinity chromatography technology	Puliyappadamba VT (2011), Puliyappadamba VT (2011)	2
NF2	1	CDK1	0	affinity chromatography technology	Zhou L (2015)	1
CDK1	0	WEE1	2	enzymatic study	Watanabe N (2004)	1
CCNB1	3	RB1	2	enzymatic study, enzymatic study	Jiang W (1998), Knudsen ES (1997)	2
PHF8	6	CDC27	2	affinity chromatography technology	Lim HJ (2013)	1
CDKN2A	1	ANAPC15	0	two hybrid	Daakour S (2016)	1
CCNB1	3	CCNF	2	affinity chromatography technology	Kong M (2000)	1
MYC	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	RRM2	2	affinity chromatography technology	Choudhury NR (2017)	1
SRP68	2	CDC27	2	affinity chromatography technology	Huttlin EL (2017)	1
USP37	1	ANAPC15	0	bioid	Yeh C (2015)	1
CDT1	2	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Nishitani H (2004), Liu E (2004)	2
RASSF1	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
CHEK1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Leung-Pineda V (2009), Huh J (2013), Williamson EA (2014)	4
CDK2	0	USP37	1	enzymatic study, bioid	Huang X (2011), Yeh C (2015)	2
CDK4	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RRM2	2	CDC27	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MYC	2	MAP2K3	1	genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Toyoshima M (2012), Ivanov AA (2017), Ivanov AA (2017), Ivanov AA (2017)	4
HECW2	13	UBE2D3	1	pull down	Miyazaki K (2003)	1
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
CCNB1	3	FZR1	1	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Ke PY (2004), Huang NJ (2012), Pfleger CM (2001), Miller JJ (2006), Song MS (2011), Frye JJ (2013), Lau AW (2013), Brown NG (2014), Summers MK (2009), ODonovan KJ (2010), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Lu L (2013), Yamaguchi M (2015), Brown NG (2015), Chen TC (2014), Williamson A (2011), Qiao R (2016), Brown NG (2016), Huttlin EL (2017)	22
GMNN	0	CDKN2A	1	pull down, two hybrid	Ramachandran N (2004), Daakour S (2016)	2
ANAPC10	0	CDC26	0	biochemical	Wan C (2015)	1
RRM2	2	WEE1	2	genetic interference	Shen JP (2017)	1
CHEK2	2	CDC14A	4	genetic interference	Srivas R (2016)	1
FZR1	1	SMURF1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Kannan M (2012), Kannan M (2012), Wan L (2011), Wan L (2011), Wan L (2011), Wan L (2011)	6
MET	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Jang KW (2011), Prince TL (2015)	2
RRM2	2	TP53	0	affinity chromatography technology	Xue L (2003)	1
TACC3	1	CDC27	2	affinity chromatography technology	Ohoka N (2014)	1
MAP2K5	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	RACGAP1	2	affinity chromatography technology	Nishimura K (2013)	1
STK11	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DNM1L	3	RRM2	2	two hybrid	DeGrado-Warren J (2008)	1
CDK5	0	RB1	2	enzymatic study	Moorthamer M (1999)	1
ANAPC4	0	ANAPC11	0	affinity chromatography technology, biochemical, biochemical, pull down, biochemical, affinity chromatography technology	Mansfeld J (2011), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015)	6
PRKN	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Staropoli JF (2003), Veeriah S (2010), Veeriah S (2010), Gong Y (2014), Gong Y (2014)	5
ANAPC11	0	UBE2D1	0	pull down, pull down, pull down, pull down	Wu T (2010), Townsend K (2009), Summers MK (2009), Cao J (2015)	4
FZR1	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ZC3HC1	1	PLK1	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2D1	0	HIF1A	1	enzymatic study	Miller F (2005)	1
CCNE1	1	CDC6	0	enzymatic study	Jiang W (1999)	1
LATS2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	CDC25A	2	enzymatic study	Chang KH (2012)	1
CDC20	1	ANAPC7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Townsend K (2009), Townsend K (2009), Townsend K (2009), Sedgwick GG (2012), Fogeron ML (2013), Hein JB (2014), Vodermaier HC (2003), Kelly A (2014), Craney A (2016), Craney A (2016), Qiao R (2016), Hein JB (2016)	13
CDC20	1	AURKA	1	affinity chromatography technology, affinity chromatography technology	Farruggio DC (1999), Katayama H (2012)	2
ANAPC13	0	ANAPC7	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
RASSF1	3	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
ERBB2	6	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MOAP1	0	SIRT2	1	affinity chromatography technology	Huttlin EL (2017)	1
BECN1	2	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	FZR1	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Jin L (2008), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Williamson A (2011), Huttlin EL (2017), Choudhury R (2016)	8
GLIS2	2	HIF1A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	PLK1	0	affinity chromatography technology, enzymatic study	Koch HB (2007), Xiao D (2016)	2
SKIL	3	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Ikeuchi Y (2014), Ikeuchi Y (2014)	2
NF2	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
CDC27	2	NUP98	5	affinity chromatography technology	Salsi V (2016)	1
TERT	7	UBE2D3	1	two hybrid, affinity chromatography technology	Wang W (2013), Wang W (2013)	2
USP1	4	UBE2K	0	enzymatic study	Das DS (2017)	1
STAU1	1	FMR1	1	affinity chromatography technology	Brendel C (2004)	1
ANAPC2	0	UBE2C	1	pull down, biochemical, pull down, x-ray crystallography, pull down	Tang Z (2001), Reddy SK (2007), Tang Z (2001), Brown NG (2015), Brown NG (2015)	5
ARNT	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	CCNB1	3	enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Garnett MJ (2009), ODonovan KJ (2010), Ke PY (2004), Braunstein I (2007), van Zon W (2010), van Zon W (2010), Pfleger CM (2001), Wolthuis R (2008), Kwan PS (2013), Tian W (2012), Han JS (2013), Lim HJ (2013), Han JS (2014), Brown NG (2014), Townsend K (2009), Sedgwick GG (2013), Lara-Gonzalez P (2011), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Wu T (2010), Uzunova K (2012), Shoji S (2014), Sedgwick GG (2013), Lara-Gonzalez P (2011), Diaz-Martinez LA (2015), Brown NG (2015), Lischetti T (2014), Tipton AR (2013), Lee SB (2015), Lee SB (2015), Jia L (2016)	33
CCNF	2	CDC20	1	affinity chromatography technology	Choudhury R (2016)	1
CDC25A	2	CDC20	1	affinity chromatography technology	Li X (2016)	1
FZR1	1	STAU1	1	affinity chromatography technology, affinity chromatography technology	Boulay K (2014), Boulay K (2014)	2
ANAPC11	0	CCNA2	1	affinity chromatography technology	Kikuchi R (2014)	1
MAPK8	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Hu MC (1997), Yin ZM (2004), Yin ZM (2004), Fuchs SY (1998), Topisirovic I (2009), Drago-Ferrante R (2008), Wang J (2000), Chang NS (2003), Fuchs SY (1998)	9
BECN1	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDC1	8	FANCD2	3	affinity chromatography technology	Stewart GS (2003)	1
TERT	7	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	ANAPC7	2	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Mansfeld J (2011), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Sedgwick GG (2013), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Sedgwick GG (2016)	10
CDKN2A	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	USP1	4	genetic interference	Xie L (2013)	1
TRIM25	5	ANAPC11	0	affinity chromatography technology	Choudhury NR (2017)	1
HIF1A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	PDGFRA	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Mansfeld J (2011), Izawa D (2011), Sedgwick GG (2012), Hein JB (2014), Di Fiore B (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Boekhout M (2015), Sedgwick GG (2016), Izawa D (2012), Salsi V (2016)	13
MAD2L2	0	CDC20	1	pull down, affinity chromatography technology	Chen J (2001), Chen J (2001)	2
MYC	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STAU1	1	SRP68	2	affinity chromatography technology	Milev MP (2012)	1
AKT1	1	EPSTI1	0	two hybrid	Arroyo R (2015)	1
GLIS2	2	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
C16orf87	0	CDC27	2	affinity chromatography technology	Huttlin EL (2017)	1
CCND1	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang H (1993), Zhang H (1993), Hein MY (2015), Huttlin EL (2017)	4
CHEK2	2	CDC25A	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down	Jin J (2008), Hassepass I (2003), Sorensen CS (2003), Falck J (2001), Falck J (2001)	5
PHF8	6	ANAPC2	0	affinity chromatography technology	Lim HJ (2013)	1
UBE2S	2	FBXO5	2	affinity chromatography technology	Wang W (2013)	1
ANAPC10	0	CDC23	3	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
CCNB1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Yang Q (2000), Pines J (1989), Kong M (2000), Amador V (2007), Paulsen MT (2006), Niida H (2005), Pereg Y (2010), Tamura D (2010), Kiviharju-af Haellstroem TM (2007), Pan ZQ (1993), Pan ZQ (1993), Pan ZQ (1993), van Zon W (2010), Desai D (1995), Vazquez-Novelle MD (2010), Smith EM (2008), Poon RY (1996), OConnor PM (1993), Fosbrink M (2009), Linares JF (2011), Varjosalo M (2013), Felzien LK (1998), Toby GG (2003), So J (2015), Huttlin EL (2015), Wan C (2015), Jenkins RH (2014), Hein MY (2015), Hein MY (2015), Voets E (2015), Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	34
PRKN	1	UBE2K	0	pull down	Kazlauskaite A (2014)	1
NINL	1	ANAPC2	0	affinity chromatography technology	Wang Y (2007)	1
E2F3	0	CCNB1	3	affinity chromatography technology	von Eyss B (2011)	1
CKS1B	0	CCNA1	3	pull down	Radulovic M (2010)	1
FZR1	1	CDC23	3	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
CCND2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	HHEX	1	affinity chromatography technology	Salsi V (2016)	1
GLIS2	2	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DAXX	5	BUB1B	0	affinity chromatography technology	Kwan PS (2013)	1
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNB1	3	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
NF2	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC26	0	ANAPC7	2	biochemical	Wan C (2015)	1
CCNA2	1	TP53	0	pull down	Luciani MG (2000)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
AURKA	1	BLID	0	two hybrid	Arroyo R (2015)	1
FZR1	1	CDC16	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
BTRC	1	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013), Fukushima H (2013)	3
ERBB2	6	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNF	2	RRM2	2	affinity chromatography technology, affinity chromatography technology	DAngiolella V (2012), DAngiolella V (2012)	2
PLK1	0	WEE1	2	enzymatic study	Watanabe N (2004)	1
MYC	2	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC14A	4	FZR1	1	enzymatic study	Bembenek J (2001)	1
FZR1	1	MOAP1	0	affinity chromatography technology, pull down, enzymatic study	Huang NJ (2012), Huang NJ (2012), Huang NJ (2012)	3
ANAPC11	0	CDC23	3	biochemical	Lu L (2013)	1
ANAPC1	1	CDC16	2	biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sumara I (2000), Hutchins JR (2010), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
MAP2K3	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KAT2A	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA4	3	FZR1	1	affinity chromatography technology	Fu AK (2011)	1
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
TRIM25	5	CDK6	0	affinity chromatography technology	Choudhury NR (2017)	1
CDC20	1	CDR2	1	enzymatic study	ODonovan KJ (2010)	1
PRKN	1	CCNA1	3	affinity chromatography technology	Staropoli JF (2003)	1
CDC20	1	E2F1	0	affinity chromatography technology, affinity chromatography technology	Nath S (2014), Peart MJ (2010)	2
MYC	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC27	2	ANAPC13	0	biochemical, biochemical, affinity chromatography technology, genetic interference	Holzmann J (2011), Havugimana PC (2012), Huttlin EL (2017), Horlbeck MA (2018)	4
SOX2	4	FZR1	1	affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013)	2
MAP2K5	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	ANAPC7	2	affinity chromatography technology	Choudhury NR (2017)	1
HSP90AA1	7	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	5
AKT1	1	AKT1S1	1	enzymatic study	Sancak Y (2007)	1
BECN1	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	MTA3	3	two hybrid	Arroyo R (2015)	1
TEAD2	2	HOXD13	0	affinity chromatography technology	Li X (2015)	1
MYC	2	VHL	0	affinity chromatography technology, affinity chromatography technology	Hwang IY (2012), Hwang IY (2012)	2
TRIM25	5	PHF8	6	affinity chromatography technology	Choudhury NR (2017)	1
EMILIN1	1	CDC27	2	affinity chromatography technology, biochemical, imaging technique	Ban KH (2007), Ban KH (2007), Ban KH (2007)	3
HSP90AA1	7	ARNT	1	affinity chromatography technology	Isaacs JS (2004)	1
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
AURKA	1	CDKN2A	1	affinity chromatography technology	Ewing RM (2007)	1
BECN1	2	PRKDC	12	affinity chromatography technology	Behrends C (2010)	1
HSP90AA1	7	RB1	2	genetic interference	Srivas R (2016)	1
RNF34	1	HSPA2	3	affinity chromatography technology	Huttlin EL (2017)	1
RB1	2	CDC16	2	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
TK1	0	CDK4	2	two hybrid	Vinayagam A (2011)	1
CCNB1	3	CDC14A	4	affinity chromatography technology	Paulsen MT (2006)	1
AURKA	1	HSP90AA1	7	affinity chromatography technology	Fogeron ML (2013)	1
MAP3K5	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2S	2	UBE2C	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
PIM1	2	CDC20	1	affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010)	2
CDK2	0	PRKDC	12	affinity chromatography technology	Neganova I (2011)	1
ANAPC1	1	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
BECN1	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TEAD2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	TTK	4	affinity chromatography technology	Cui Y (2010)	1
PRKDC	12	ANAPC2	0	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
PTEN	24	UBE2D1	0	genetic interference	Vizeacoumar FJ (2013)	1
TP53	0	KAT2A	1	affinity chromatography technology, fluorescent resonance energy transfe	Gamper AM (2008), Ivanov AA (2017)	2
CCNE1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	GLB1	3	affinity chromatography technology	Huttlin EL (2017)	1
CHEK2	2	RB1	2	enzymatic study, pull down, affinity chromatography technology	Inoue Y (2007), Inoue Y (2007), Inoue Y (2007)	3
TP53	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PAX3	6	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Cao J (2015), Cao J (2015), Cao J (2015), Cao J (2015)	4
CDK6	0	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC13	0	ANAPC10	0	affinity chromatography technology	Huttlin EL (2017)	1
PIM1	2	CDC25A	2	pull down, affinity chromatography technology	Mochizuki T (1999), Mochizuki T (1999)	2
PTTG1	0	AURKA	1	pull down, genetic interference	Kim HS (2009), Horlbeck MA (2018)	2
TRIM25	5	DDB1	6	affinity chromatography technology	Choudhury NR (2017)	1
AKT1	1	ARNT	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe	Li YM (2005), Li YM (2005), Li YM (2005), Ivanov AA (2017)	4
MET	7	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	BRSK2	5	affinity chromatography technology	Choudhury NR (2017)	1
ANAPC2	0	ANAPC5	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Gmachl M (2000), Vodermaier HC (2003), Vodermaier HC (2003)	4
FBXO5	2	ANAPC5	2	affinity chromatography technology, pull down	Miller JJ (2006), Miller JJ (2006)	2
SKP2	2	AURKB	2	affinity chromatography technology	Wu J (2015)	1
PHF8	6	CDC20	1	affinity chromatography technology, affinity chromatography technology	Lim HJ (2013), Lim HJ (2013)	2
MYC	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS2	0	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CCND2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC23	3	NEK2	2	affinity chromatography technology	Hein MY (2015)	1
ANAPC5	2	CDC23	3	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
FZR1	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RRM2	2	VHL	0	genetic interference	Shen JP (2017)	1
STK11	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nony P (2003), Brajenovic M (2004), Gaude H (2012), Taipale M (2012), Huttlin EL (2017)	5
CDK4	2	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto M (1999), Sugimoto M (1999), Serrano M (1993), Lin J (2001), Taules M (1998), Cariou S (2000), Coleman KG (1997), Jose-Eneriz ES (2008), Jose-Eneriz ES (2008), Diehl JA (1997), Okabe H (2007), Bustany S (2011), Gladden AB (2003), Sweeney KJ (1997), Musgrove EA (1996), Vlach J (1996), Garcia-Morales P (2006), Bindra RS (2002), Ruas M (2007), Poon RY (1996), Ramachandran N (2004), Larrea MD (2009), Waaijers S (2013), Mallampalli RK (2013), Rolland T (2014), Chen TC (2014), Barbash O (2009), Datta D (2015), Hukkelhoven E (2012), Hukkelhoven E (2012), Ghiani C (2001), Ito H (2016), Huttlin EL (2017), Roessig L (2001), Qie S (2017)	35
SENP2	3	DAXX	5	enzymatic study	Lin DY (2006)	1
PTEN	24	HSP90AA1	7	affinity chromatography technology, genetic interference	Maddika S (2011), Shen JP (2017)	2
CDCA3	0	CUL1	7	affinity chromatography technology, pull down	Ayad NG (2003), Ayad NG (2003)	2
CDC14A	4	PLK1	0	affinity chromatography technology, enzymatic study	van Leuken R (2009), van Leuken R (2009)	2
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
KAT2A	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2S	2	ANAPC1	1	pull down	Brown NG (2014)	1
SKP2	2	CDC14B	1	affinity chromatography technology, enzymatic study	Calvisi DF (2009), Rodier G (2008)	2
CDC27	2	MAD2L2	0	affinity chromatography technology	Uzunova K (2012)	1
RRM2	2	ANAPC4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2S	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Hu L (2017), Hu L (2017), Hu L (2017)	3
ANAPC4	0	HHEX	1	affinity chromatography technology	Salsi V (2016)	1
CDC23	3	ANAPC7	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Boldt K (2016)	3
RRM2	2	SKP2	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Xiao GG (2008), Xiao GG (2008), Xiao GG (2008)	3
PRKDC	12	KAT2A	1	enzymatic study	Barlev NA (1998)	1
RASSF1	3	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Jiang L (2011), Jiang L (2011), Jiang L (2011)	3
TP53	0	CDK5	0	affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007)	3
CDK4	2	VHL	0	genetic interference	Shen JP (2017)	1
AURKB	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
CDK6	0	VHL	0	genetic interference	Shen JP (2017)	1
FZR1	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
GLIS2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
USP37	1	PLK1	0	affinity chromatography technology	Burrows AC (2012)	1
PRKN	1	UBE2D3	1	pull down, pull down, pull down	Shin JH (2011), Wenzel DM (2011), Kazlauskaite A (2014)	3
RASSF1	3	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKIL	3	RB1	2	affinity chromatography technology	Tokitou F (1999)	1
HIF1A	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Guidato S (1998), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	6
USP37	1	ANAPC5	2	affinity chromatography technology, bioid	Huang X (2011), Yeh C (2015)	2
AURKA	1	MTA3	3	two hybrid	Arroyo R (2015)	1
HSP90AA1	7	MAP3K5	1	affinity chromatography technology	Taipale M (2012)	1
MET	7	PTEN	24	genetic interference	Shen JP (2017)	1
CCND2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	RRM2	2	genetic interference	Shen JP (2017)	1
CDC20	1	DCPS	1	enzymatic study, enzymatic study	Zhang S (2016), Li Q (2016)	2
CDC6	0	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Petersen BO (1999), Petersen BO (1999), Saha P (1998), Jiang W (1999)	4
MDC1	8	ANAPC5	2	affinity chromatography technology, affinity chromatography technology	Coster G (2007), Woods NT (2012)	2
GLIS2	2	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC15	0	ANAPC10	0	affinity chromatography technology, affinity chromatography technology	Uzunova K (2012), Hein MY (2015)	2
CDK2	0	SIRT2	1	enzymatic study	Movahedi Naini S (2015)	1
PRKN	1	CCND1	1	affinity chromatography technology, enzymatic study	Gong Y (2014), Gong Y (2014)	2
CDC6	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Hubbi ME (2013), Hubbi ME (2013)	2
MYC	2	DDB1	6	affinity chromatography technology	Choi SH (2010)	1
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
PIM1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010), Cen B (2010), Cen B (2010)	4
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
TRIM25	5	TRIM33	4	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	PSMC3IP	0	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
FGFR4	6	MTA3	3	two hybrid	Arroyo R (2015)	1
SKP2	2	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Marti A (1999), Zhang Z (2005), Farhana L (2002), Salon C (2007), Swarnalatha M (2013)	6
PDGFRA	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
FZR1	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	EPHA4	3	affinity chromatography technology	Yokote H (2005)	1
STK11	2	CYP17A1	5	two hybrid	Arroyo R (2015)	1
ANAPC2	0	PTTG1	0	enzymatic study, pull down	Vodermaier HC (2003), Qiao R (2016)	2
TRIM25	5	CDC26	0	affinity chromatography technology	Choudhury NR (2017)	1
UBE2C	1	CDC20	1	biochemical, pull down	Reddy SK (2007), Garnett MJ (2009)	2
FZR1	1	BUB1B	0	enzymatic study, pull down	Tian W (2012), Diaz-Martinez LA (2015)	2
C16orf87	0	ANAPC4	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK5	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
CDK2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Varjosalo M (2013)	2
MAP2K5	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	CCND1	1	affinity chromatography technology	Choudhury NR (2017)	1
TEAD2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K5	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	LATS2	1	x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Li Y (2015), Yin F (2013), Ivanov AA (2017), Zhu C (2018)	4
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
HIF1A	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Kim AH (2001), Kim AH (2001)	2
MAP2K5	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO5	2	CDC20	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hsu JY (2002), Hsu JY (2002), Reimann JD (2001), Reimann JD (2001), Voets E (2015)	5
EPHA2	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBE2S	2	CDC27	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Brown NG (2014), Kelly A (2014), Craney A (2016)	4
CDK6	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNB1	3	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jeganathan KB (2006), Farhana L (2002), van Zon W (2010), Miller JJ (2006), Voets E (2015)	5
HSP90AA1	7	MAP2K5	1	affinity chromatography technology	Taipale M (2012)	1
NINL	1	PLK1	0	affinity chromatography technology, two hybrid, enzymatic study, bioid	Casenghi M (2003), Casenghi M (2003), Casenghi M (2003), Gupta GD (2015)	4
PTEN	24	PDGFRA	3	affinity chromatography technology	Crockett DK (2005)	1
AURKA	1	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	WEE1	2	affinity chromatography technology, enzymatic study, pull down, bioid	Watanabe N (2004), Watanabe N (2004), Watanabe N (2004), Coyaud E (2015)	4
EYA1	4	FZR1	1	affinity chromatography technology, affinity chromatography technology	Sun J (2012), Sun J (2012)	2
SMURF1	4	VHL	0	affinity chromatography technology	Zhang C (2016)	1
ARNT	1	GMNN	0	two hybrid	Wang J (2011)	1
MET	7	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2B	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	MCPH1	4	pull down	Alderton GK (2006)	1
TP53	0	AURKB	2	affinity chromatography technology	Wu L (2011)	1
UBE2S	2	ANAPC4	0	pull down, pull down	Brown NG (2014), Brown NG (2014)	2
ARNT	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IST1	0	CDC20	1	affinity chromatography technology	Zhang X (2011)	1
CCNB1	3	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Hein MY (2015), Huttlin EL (2017)	3
AURKA	1	PLK1	0	affinity chromatography technology, biochemical	Katayama H (2008), Havugimana PC (2012)	2
PHF8	6	ANAPC4	0	affinity chromatography technology	Lim HJ (2013)	1
ANAPC11	0	ANAPC10	0	pull down	Tang Z (2001)	1
MET	7	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HECW2	13	CDC23	3	affinity chromatography technology	Lu L (2013)	1
EMILIN1	1	FZR1	1	affinity chromatography technology	Ban KH (2007)	1
KAT2A	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RRM2B	1	TP53	0	affinity chromatography technology	Xue L (2003)	1
HIF1A	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC20	1	BTRC	1	affinity chromatography technology	Guardavaccaro D (2008)	1
ANAPC10	0	LNP1	1	affinity chromatography technology	Salsi V (2016)	1
LATS2	1	ANAPC7	2	affinity chromatography technology	Zhu C (2018)	1
FZR1	1	BEX1	0	two hybrid	Arroyo R (2015)	1
SIRT2	1	SKP2	2	affinity chromatography technology	Li Z (2016)	1
TERT	7	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	SKP2	2	affinity chromatography technology	Couzens AL (2013)	1
CCND2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nicolas E (2001), Pardo PS (2002), Choubey D (1996), Fajas L (2000), Dyson N (1993), Dyson N (1993), Wu CL (1995), Taniura H (1998), Dai Y (2003), Fedele M (2006), Fedele M (2006), Brown VD (2002), De Blasio A (2005), Chau CM (2008), Dasgupta P (2004), Yang L (2011), Kruetzfeldt M (2005), Harbour JW (1999), Lee SJ (1998), Gao D (2009), Delston RB (2011), Gupta K (2000), Sdek P (2004), Flemington EK (1993), Chang YH (2012), Inoue Y (2007), Inoue Y (2007), Inoue Y (2007), Liu X (2006), Moberg K (1996), Knudsen ES (1996), Brown VD (1999), Brown VD (1999), Whitaker LL (1998), Whitaker LL (1998), Hagemeier C (1993), Bhat UG (1999), Xiao B (2003), Xiao B (2003), Vidal M (1996), Markham D (2006), Markham D (2006), Ianari A (2009), Ianari A (2009), Dhillon NK (2002), Knudsen ES (1997), Knudsen ES (1997), Gery S (2004), Gery S (2004), Kashuba E (2008), Kashuba E (2008), Pearson A (1997), Ginsberg D (1994), Welch PJ (1995), Wang J (2009), Aoki I (2012), Trimarchi JM (1998), Kumari A (2015), Gamell C (2017), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	63
HSP90AA1	7	TEAD2	2	affinity chromatography technology	Taipale M (2012)	1
FZR1	1	TTK	4	affinity chromatography technology	Cui Y (2010)	1
FZR1	1	PCLAF	0	enzymatic study, pull down	Williamson A (2011), Williamson A (2011)	2
GLIS2	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
BECN1	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CLSPN	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Gao D (2009), Bassermann F (2008), Bassermann F (2008)	3
CCNE1	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McKenzie PP (2003), Shanahan F (1999), Koff A (1992), Koff A (1992), Mayer C (2004), Connor MK (2003), Boudrez A (2000), Varshochi R (2005), Jeong JH (2010), Bustany S (2011), Yeh ES (2006), Hui S (2011), Kim J (2007), Kiviharju-af Haellstroem TM (2007), Abbas T (2007), Nishimura T (2005), Matsumoto Y (2004), Harwell RM (2004), Harwell RM (2004), Peiretti A (2003), Peiretti A (2003), Kim YB (2000), Manenti S (1999), Datta NS (1998), Sheaff RJ (1997), Higashi H (1996), Higashi H (1996), Musgrove EA (1996), Vlach J (1996), Grim JE (2008), Liu S (2009), Ciarallo S (2002), Desai D (1995), Baydoun HH (2010), Baydoun HH (2010), Chu I (2007), Chu I (2007), Levkau B (1998), Poon RY (1996), Zhao J (1998), Zhao J (1998), Larrea MD (2009), Varjosalo M (2013), Varjosalo M (2013), Chan HM (2001), So J (2015), Ungermannova D (2005), Song MS (2011), Huttlin EL (2015), Hein MY (2015), Lin CH (2015), Lin CH (2015), Davis RJ (2017), Huttlin EL (2017)	54
CUL1	7	E2F1	0	affinity chromatography technology, pull down	Marti A (1999), Marti A (1999)	2
CCND2	2	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BUB1B	0	ANAPC2	0	affinity chromatography technology	So J (2015)	1