PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
PDK1 1 ATG4A 1 affinity chromatography technology Hein MY (2015) 1
PDHB 1 PDK1 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
ACAD9 1 DLAT 1 biochemical Havugimana PC (2012) 1
EGFR 5 HLA-B 0 affinity chromatography technology Yao Z (2017) 1
TNK2 7 PDK1 1 affinity chromatography technology Zhang J (2015) 1
LAMP3 1 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
PIK3CA 8 PDK1 1 protein complementation assay Miao B (2010) 1
PDK1 1 PDK2 4 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Boulatnikov I (2003), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017) 4
PDK3 0 PDHA1 7 affinity chromatography technology Huttlin EL (2017) 1
OXLD1 1 TRMT61B 2 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MYC 2 ARNT 1 fluorescent resonance energy transfe Ivanov AA (2017) 1
MYC 2 PDK1 1 genetic interference Toyoshima M (2012) 1
SLC18A1 2 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
PDK1 1 CRBN 2 affinity chromatography technology Huttlin EL (2017) 1
DLAT 1 PDHX 2 pull down, biochemical, two hybrid Hiromasa Y (2004), Havugimana PC (2012), Wang J (2011) 3
PDK1 1 RALGDS 4 affinity chromatography technology Tian X (2002) 1
PDK1 1 SPG7 6 affinity chromatography technology Hein MY (2015) 1
MTOR 14 RPTOR 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Schalm SS (2003), Hara K (2002), Ha SH (2006), Wang L (2006), Frias MA (2006), Frias MA (2006), Buerger C (2006), Jacinto E (2006), McMahon LP (2005), Oshiro N (2004), Kawai S (2003), Choi KM (2003), Hara K (2002), Hara K (2002), Kim DH (2002), Kim DH (2002), Schieke SM (2006), Ha SH (2006), Wang L (2006), Frias MA (2006), Buerger C (2006), Sarbassov DD (2006), Tzatsos A (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Kwak D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Gwinn DM (2010), Sancak Y (2007), Sancak Y (2007), Yang Q (2006), Carriere A (2011), Jacinto E (2006), Rosner M (2010), Kim DH (2003), Kim DH (2003), Carriere A (2008), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Hussain S (2013), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Yan X (2012), Ramirez-Rangel I (2011), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Linares JF (2013), Coffman K (2014), Oshiro N (2014), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), Dan HC (2008), Dan HC (2008), Dan HC (2008), Hong F (2008), Hong F (2008), Choo AY (2008), Toschi A (2009), Loewith R (2002), Xu Y (2013), Sancak Y (2010), Sancak Y (2010), Vander Haar E (2007), Vander Haar E (2007), Kaadige MR (2015), Misra UK (2014), Misra UK (2014), Thedieck K (2007), Thomas JD (2014), Park D (2014), Alayev A (2016), Alayev A (2016) 91
NSFL1C 1 HIF1A 1 affinity chromatography technology Alexandru G (2008) 1
PDK1 1 SRCAP 30 affinity chromatography technology Hein MY (2015) 1
RPTOR 4 RPS6KB1 1 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study Ali SM (2005), Ha SH (2006), Hara K (2002), Nojima H (2003), Kwak D (2012), Carriere A (2011), Ha SH (2006), Li L (2013), Garcia-Martinez JM (2009) 9
PDK4 0 PDK3 0 affinity chromatography technology Huttlin EL (2017) 1
EGFR 5 ILKAP 2 two hybrid Yao Z (2017) 1
PDHB 1 PDHX 2 biochemical, biochemical, affinity chromatography technology, affinity chromatography technology Liu S (1995), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017) 4
PDK1 1 PDHA1 7 affinity chromatography technology, pull down Huttlin EL (2015), Fan J (2014) 2
PDHA1 7 PDHX 2 biochemical Havugimana PC (2012) 1
ARNT 1 PDK1 1 imaging technique Kumar P (2015) 1
LAMTOR5 1 PDK1 1 two hybrid Fan W (2013) 1
APLNR 1 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
USP4 3 PDK1 1 enzymatic study, affinity chromatography technology Uras IZ (2012), Uras IZ (2012) 2
PDK1 1 NECTIN3 0 affinity chromatography technology Hein MY (2015) 1
PDK1 1 VKORC1 1 affinity chromatography technology Hein MY (2015) 1
PDK1 1 DENR 2 affinity chromatography technology Huttlin EL (2017) 1
PDHB 1 PDHA1 7 biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology Liu S (1995), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Malty RH (2017) 6
PDK1 1 RASSF8 2 affinity chromatography technology Hein MY (2015) 1
PDK1 1 283458 0 affinity chromatography technology Huttlin EL (2017) 1
FOXD4 1 PDHB 1 affinity chromatography technology Huttlin EL (2017) 1
PDK1 1 RPS6KB1 1 pull down Minami T (2001) 1
PDK1 1 PKN1 4 affinity chromatography technology Flynn P (2000) 1
HLA-B 0 PDK1 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
PDK1 1 HMGN1 0 affinity chromatography technology Hein MY (2015) 1
PIK3CA 8 SGK1 4 pull down Park J (1999) 1
PDK1 1 PYCR2 1 affinity chromatography technology Hein MY (2015) 1
PDK1 1 ILKAP 2 affinity chromatography technology Hein MY (2015) 1
EGFR 5 COG4 3 affinity chromatography technology Foerster S (2013) 1
PDHB 1 PDK2 4 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
HIF1A 1 PDK1 1 imaging technique Kumar P (2015) 1
PDK1 1 RPTOR 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hara K (2002), Misra UK (2014), Misra UK (2014) 3
CCDC93 2 PDK1 1 affinity chromatography technology Hein MY (2015) 1
NDUFS7 1 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
FOXD4 1 PDK3 0 affinity chromatography technology Huttlin EL (2017) 1
FOXD4 1 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
EGFR 5 TNK2 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology Lin Q (2010), Pao-Chun L (2009), Shen F (2007), Howlin J (2008), Howlin J (2008), Tong J (2008), Jones S (2014), Jones S (2014), Chua BT (2010) 9
PDK1 1 COG4 3 affinity chromatography technology Hein MY (2015) 1
RPS6KB1 1 KAT2B 2 affinity chromatography technology, affinity chromatography technology, enzymatic study Fenton TR (2010), Fenton TR (2010), Fenton TR (2010) 3
SGK1 4 RPTOR 4 affinity chromatography technology Hong F (2008) 1
PDK4 0 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
MTOR 14 SGK1 4 enzymatic study, affinity chromatography technology, affinity chromatography technology Hong F (2008), Hong F (2008), Hong F (2008) 3
PDK1 1 STXBP2 6 affinity chromatography technology Hein MY (2015) 1
KAT2B 2 PDK1 1 enzymatic study Sundaresan NR (2011) 1
PDK1 1 ITGB3 6 enzymatic study Kirk RI (2000) 1
ACAD9 1 PDK2 4 affinity chromatography technology Huttlin EL (2017) 1
EGFR 5 PDK1 1 affinity chromatography technology Tong J (2014) 1
APLNR 1 SPG7 6 affinity chromatography technology Huttlin EL (2017) 1
ACAD9 1 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
PDK2 4 DLAT 1 pull down, pull down Hiromasa Y (2003), Tuganova A (2002) 2
ACAD9 1 PDK3 0 affinity chromatography technology Huttlin EL (2017) 1
CBFA2T3 3 PDK1 1 imaging technique Kumar P (2015) 1
MTOR 14 PDK1 1 genetic interference, affinity chromatography technology, affinity chromatography technology Isotani S (1999), Misra UK (2014), Misra UK (2014) 3
PDK2 4 PDHX 2 pull down Hiromasa Y (2003) 1
KAT2B 2 MYC 2 enzymatic study Patel JH (2004) 1
PDK1 1 PKN2 6 affinity chromatography technology Flynn P (2000) 1
RPS6KB1 1 MTOR 14 affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology Chiang GG (2005), Holz MK (2005), Holz MK (2005), Hara K (2002), Isotani S (1999), Long X (2005), Toral-Barza L (2005), Ali SM (2005), Saitoh M (2002), Kim DH (2002), Edinger AL (2003), Leone M (2006), Takahashi T (2000), Burnett PE (1998), Sarbassov DD (2005), Agrawal P (2012), Sancak Y (2007), Oshiro N (2004), Sarbassov DD (2005), Kim DH (2003), Kim DH (2003), Nojima H (2003), Martin J (2008), Wing LY (2005), Ren HY (2015) 25
FOXD4 1 DLAT 1 affinity chromatography technology Huttlin EL (2017) 1
DLAT 1 PDHB 1 pull down, affinity chromatography technology, biochemical, affinity chromatography technology Hiromasa Y (2004), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 4
EGFR 5 PYCR2 1 affinity chromatography technology Tong J (2014) 1
TRMT61B 2 PDK1 1 affinity chromatography technology Huttlin EL (2017) 1
FOXD4 1 PDHX 2 affinity chromatography technology Huttlin EL (2017) 1
PDHB 1 PDK3 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
PDK1 1 NRBP2 2 affinity chromatography technology Hein MY (2015) 1
PDK1 1 PDK1 1 enzymatic study Hayashi T (2007) 1
HIF1A 1 MYH1 2 affinity chromatography technology Huttlin EL (2017) 1
HIF1A 1 CBFA2T3 3 pull down, pull down, affinity chromatography technology, affinity chromatography technology Kumar P (2015), Kumar P (2015), Kumar P (2015), Kumar P (2015) 4
ARNT 1 HIF1A 1 affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, two hybrid, imaging technique, fluorescent resonance energy transfe, fluorescent resonance energy transfe, pull down, two hybrid, two hybrid Woods SL (2002), Hogenesch JB (1997), Hogenesch JB (1997), Behrends C (2010), Wang F (2004), Lim W (2011), Sufan RI (2009), Sufan RI (2009), Katschinski DM (2004), Katschinski DM (2004), Chun YS (2002), Hein MY (2015), Huttlin EL (2017), Kalousi A (2010), Kalousi A (2010), Isaacs JS (2004), Chilov D (1999), Chilov D (1999), Chilov D (1999), Kallio PJ (1997), Amir S (2009), Yang L (2008), Hur E (2002), Lando D (2000), Sadek CM (2000), Chapman-Smith A (2006), Suzuki H (2001), Suzuki H (2001), Li YM (2005), Jiang BH (1996), Jiang BH (1996), Jiang BH (1996), Jiang BH (1996), Park EJ (2006), Park EJ (2006), Ruas JL (2005), Wotzlaw C (2007), Ivanov AA (2017), Depping R (2004), Depping R (2004), Depping R (2004) 41
XRCC6 3 HIF1A 1 affinity chromatography technology, affinity chromatography technology Um JH (2004), Um JH (2004) 2
PDK1 1 PDK3 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017) 3
PDK1 1 TRIM47 2 affinity chromatography technology Hein MY (2015) 1
PDK1 1 NSFL1C 1 affinity chromatography technology Hein MY (2015) 1
DLAT 1 PDHA1 7 biochemical, biochemical Havugimana PC (2012), Wan C (2015) 2
PDK1 1 RIMS1 6 affinity chromatography technology Hein MY (2015) 1
PDK1 1 SGK1 4 enzymatic study Seong HA (2007) 1
PDK1 1 XRCC6 3 two hybrid Vinayagam A (2011) 1
PDHA1 7 PYCR2 1 affinity chromatography technology Malty RH (2017) 1
HIF1A 1 RPTOR 4 affinity chromatography technology Land SC (2007) 1
TRMT61B 2 ACAD9 1 affinity chromatography technology Huttlin EL (2017) 1
PDK1 1 CELF2 5 affinity chromatography technology Hein MY (2015) 1
MYC 2 HIF1A 1 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Koshiji M (2004), Koshiji M (2004), Ivanov AA (2017) 3
PDK1 1 MKNK1 0 affinity chromatography technology Hein MY (2015) 1
EGFR 5 PDK3 0 protein complementation assay Deribe YL (2009) 1
PDK1 1 VWA8 5 affinity chromatography technology Hein MY (2015) 1
FOXD4 1 PDHA1 7 affinity chromatography technology Huttlin EL (2017) 1
MYH1 2 RIMS1 6 biochemical Wan C (2015) 1
PDK1 1 PDHX 2 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
PDK3 0 PDK2 4 affinity chromatography technology Huttlin EL (2017) 1
HLA-DPA1 1 PDK1 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
DLAT 1 PDK1 1 pull down Tuganova A (2002) 1
PIK3CA 8 EGFR 5 fluorescent resonance energy transfe Ivanov AA (2017) 1
PDK1 1 MYH1 2 affinity chromatography technology Hein MY (2015) 1
PDK1 1 COL4A5 2 affinity chromatography technology Hein MY (2015) 1
PDK3 0 PDHX 2 affinity chromatography technology Huttlin EL (2017) 1
DLAT 1 PDK3 0 pull down, affinity chromatography technology Tuganova A (2002), Huttlin EL (2017) 2
FOXD4 1 PDK2 4 affinity chromatography technology Huttlin EL (2017) 1
PIK3CA 8 MYC 2 fluorescent resonance energy transfe Ivanov AA (2017) 1
EGFR 5 MTOR 14 affinity chromatography technology Foerster S (2013) 1
PDK4 0 PDK2 4 affinity chromatography technology Huttlin EL (2017) 1
PDK1 1 ZNFX1 5 affinity chromatography technology Hein MY (2015) 1
KAT2B 2 XRCC6 3 enzymatic study Cohen HY (2004) 1
KAT2B 2 HIF1A 1 affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology Bodily JM (2011), Geng H (2012), Geng H (2012), Lim JH (2010) 4
NDUFS7 1 ACAD9 1 affinity chromatography technology, affinity chromatography technology Guarani V (2014), Huttlin EL (2017) 2
MYC 2 PKN1 4 genetic interference Toyoshima M (2012) 1
MYC 2 XRCC6 3 affinity chromatography technology, affinity chromatography technology Koch HB (2007), Koch HB (2007) 2
OXLD1 1 PDK1 1 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
NDUFS7 1 PDK3 0 affinity chromatography technology Huttlin EL (2017) 1