Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
PGM1	rs4643	CC	acetaldehyde	metabolism/PK	yes	Blood concentrations of acetaldehyde, a metabolite of ethanol were significantly higher at 120 minutes after dosing with alcohol in CC individuals compared to AA and AC. No significant differences were observed at any other timepoint.	Genotype CC is associated with increased concentrations of acetaldehyde in healthy individuals as compared to genotypes AA + AC.	31002879	1450936723
PGM1	rs4643	CC	ethanol	metabolism/PK	yes	Blood alcohol concentrations (BAC) were significantly lower in CC individuals compared to AA and AC at 15 and 60 minutes after alcohol dosing.	Genotype CC is associated with decreased concentrations of ethanol in healthy individuals as compared to genotypes AA + AC.	31002879	1450936689