PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
BRCA1	7	MED21	1	biochemical, affinity chromatography technology	Scully R (1997), Scully R (1997)	2
MED29	2	POLR2B	3	affinity chromatography technology	Sato S (2004)	1
SRC	2	POLR2B	3	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
PSMB9	0	POLR2H	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
ESR1	0	POLR2D	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2F	1	POLR2H	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
MYC	2	XPO1	8	affinity chromatography technology, affinity chromatography technology	Koch HB (2007), Kirli K (2015)	2
MYC	2	POLR2E	0	genetic interference	Toyoshima M (2012)	1
MED29	2	POLR2I	0	affinity chromatography technology	Sato S (2004)	1
CUL5	1	POLR2I	0	affinity chromatography technology	Bennett EJ (2010)	1
ELOA	3	POLR2F	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
GPN3	4	PIH1D1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED21	1	POLR2D	0	affinity chromatography technology	Huttlin EL (2017)	1
MED10	0	POLR2D	0	affinity chromatography technology	Sato S (2004)	1
COPS5	0	ESR1	0	affinity chromatography technology	Callige M (2005)	1
COPS5	0	CPNE2	2	affinity chromatography technology	Bennett EJ (2010)	1
MED19	1	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
PIH1D1	0	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPRD1B	1	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
GPN3	4	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2I	0	COPS5	0	biochemical	Wan C (2015)	1
PSMB9	0	ELOA	3	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
CUL5	1	5430	0	affinity chromatography technology	Bennett EJ (2010)	1
POLR2F	1	SUPT5H	2	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
MED29	2	POLR2D	0	affinity chromatography technology	Sato S (2004)	1
XPO1	8	CDKN2AIP	1	affinity chromatography technology	Kirli K (2015)	1
DCUN1D1	0	POLR2I	0	affinity chromatography technology	Bennett EJ (2010)	1
POLR2M	0	POLR2F	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
POLR2D	0	POLR2G	0	pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
SRC	2	POLR2F	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
POLR1B	2	POLR2H	0	biochemical	Wan C (2015)	1
POLR2F	1	POLR2E	0	pull down, biochemical, affinity chromatography technology	Acker J (1997), Wan C (2015), Hein MY (2015)	3
BRCA1	7	POLR2H	0	enzymatic study, enzymatic study	Wu W (2007), Vittal V (2015)	2
UXT	0	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
MED19	1	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
POLR2B	3	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
RPRD1B	1	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2B	3	POLR2E	0	pull down, pull down, biochemical, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Wan C (2015)	4
POLR2C	0	POLR2H	0	pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Ayguen O (2008), Wan C (2015)	4
RPRD1B	1	POLR2M	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2D	0	POLR2H	0	pull down	Schaller S (1999)	1
PIH1D1	0	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SRC	2	POLR2H	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
SUPT5H	2	POLR2I	0	affinity chromatography technology	Hein MY (2015)	1
LMO2	2	RPRD1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL5	1	RECQL5	3	affinity chromatography technology	Bennett EJ (2010)	1
PSMB9	0	POLR2L	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
CDKN2AIP	1	POLR2I	0	affinity chromatography technology	Hein MY (2015)	1
MED10	0	POLR2L	1	affinity chromatography technology	Sato S (2004)	1
POLR2B	3	POLR1B	2	biochemical	Wan C (2015)	1
XPO1	8	GPN3	4	affinity chromatography technology	Kirli K (2015)	1
MED29	2	MED19	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sato S (2004), Sato S (2004), Tomomori-Sato C (2004), Tomomori-Sato C (2004), Sato S (2003), Takahashi H (2011), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
POLR2E	0	POLR2L	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Huttlin EL (2017)	4
RNGTT	0	POLR2G	0	affinity chromatography technology	St-Denis N (2016)	1
POLR2C	0	POLR2K	0	pull down, pull down, biochemical	Acker J (1997), Acker J (1997), Wan C (2015)	3
BRCA1	7	CDKN2AIP	1	affinity chromatography technology	Woods NT (2012)	1
PIH1D1	0	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	5430	0	affinity chromatography technology	Kirli K (2015)	1
SRC	2	POLR2G	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
PCIF1	0	POLR2I	0	affinity chromatography technology	Hein MY (2015)	1
POLR2I	0	POLR2K	0	biochemical	Wan C (2015)	1
MED29	2	MED26	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011)	3
POLR2C	0	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
PSMB9	0	POLR2I	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2G	0	MED21	1	affinity chromatography technology	Hein MY (2015)	1
MED19	1	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
CPNE2	2	SUPT5H	2	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	XPO1	8	affinity chromatography technology	Ertych N (2016)	1
RPRD1B	1	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PSMB9	0	POLR2K	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED10	0	POLR2F	1	affinity chromatography technology	Sato S (2004)	1
LMO2	2	POLR2B	3	affinity chromatography technology	Huttlin EL (2017)	1
PSMB9	0	POLR2B	3	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED10	0	POLR2E	0	affinity chromatography technology	Sato S (2004)	1
POLR2K	0	POLR2E	0	pull down, biochemical	Acker J (1997), Wan C (2015)	2
SUPT5H	2	POLR2B	3	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
POLR2K	0	POLR2G	0	pull down	Acker J (1997)	1
POLR2G	0	POLR2F	1	pull down, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Huttlin EL (2015), Hein MY (2015)	3
GPN3	4	POLR2B	3	affinity chromatography technology	Huttlin EL (2017)	1
SYDE1	4	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
POLR2C	0	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Ayguen O (2008)	2
POLR2D	0	POLR2L	1	pull down, two hybrid, affinity chromatography technology	Schaller S (1999), Wang J (2011), Huttlin EL (2017)	3
MED29	2	POLR2F	1	affinity chromatography technology	Sato S (2004)	1
CPNE2	2	POLR2B	3	affinity chromatography technology	Huttlin EL (2017)	1
POLR2L	1	POLR2G	0	pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Acker J (1997), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
MED26	2	POLR2F	1	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
PIH1D1	0	POLR2F	1	affinity chromatography technology	Huttlin EL (2015)	1
MYC	2	RNGTT	0	affinity chromatography technology	Koch HB (2007)	1
LMO2	2	POLR2L	1	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	RPRD1B	1	affinity chromatography technology	Woods NT (2012)	1
XPO1	8	PIH1D1	0	affinity chromatography technology	Kirli K (2015)	1
MED19	1	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
SRC	2	POLR2E	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
SRC	2	5430	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
RNGTT	0	POLR2C	0	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
MED10	0	POLR2K	0	affinity chromatography technology	Sato S (2004)	1
ELOA	3	POLR2C	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
ESR1	0	MYC	2	affinity chromatography technology	Cheng AS (2006)	1
ESR1	0	PSMB9	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
XPO1	8	CPSF6	1	affinity chromatography technology	Kirli K (2015)	1
CPSF6	1	POLR2I	0	biochemical	Havugimana PC (2012)	1
MED26	2	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
PIH1D1	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED10	0	POLR2I	0	affinity chromatography technology	Sato S (2004)	1
MED19	1	MED26	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011), Tsai KL (2013), Huttlin EL (2015), Huttlin EL (2017)	6
POLR2H	0	SUPT5H	2	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
POLR2H	0	POLR2I	0	biochemical	Wan C (2015)	1
PSMB9	0	SRC	2	two hybrid, pull down, affinity chromatography technology, imaging technique, imaging technique	Zhang H (2006), Zhang H (2006), Zhang H (2006), Zhang H (2006), Zhang H (2006)	5
WDR48	2	GPN3	4	affinity chromatography technology	Sowa ME (2009)	1
MED21	1	POLR2M	0	affinity chromatography technology	Huttlin EL (2017)	1
RNGTT	0	SUPT5H	2	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
ELOA	3	POLR2I	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
CUL5	1	POLR2C	0	affinity chromatography technology	Bennett EJ (2010)	1
PSMB9	0	POLR2C	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
XPO1	8	POLR2M	0	affinity chromatography technology	Kirli K (2015)	1
MYC	2	POLR2I	0	genetic interference	Toyoshima M (2012)	1
ELOA	3	POLR2E	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
SRC	2	POLR2C	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED10	0	MED21	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Malik S (2000), Huttlin EL (2017)	3
POLR2C	0	POLR2L	1	pull down, pull down, biochemical	Acker J (1997), Acker J (1997), Wan C (2015)	3
CPNE2	2	POLR2M	0	affinity chromatography technology	Huttlin EL (2017)	1
LMO2	2	POLR2F	1	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	POLR2I	0	affinity chromatography technology	Woods NT (2012)	1
5430	0	POLR2C	0	pull down, pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	6
MED21	1	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
LMO2	2	POLR2D	0	affinity chromatography technology	Huttlin EL (2017)	1
RPRD1B	1	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UXT	0	GPN3	4	affinity chromatography technology	Huttlin EL (2017)	1
GPN3	4	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
UXT	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Gstaiger M (2003), Huttlin EL (2017)	2
MED19	1	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2015), Huttlin EL (2017)	4
POLR2C	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
MED10	0	5430	0	affinity chromatography technology, affinity chromatography technology, biochemical	Sato S (2004), Sato S (2004), Wan C (2015)	3
MED21	1	SRC	2	affinity chromatography technology	Huttlin EL (2017)	1
UXT	0	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
CPNE2	2	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
MED19	1	POLR2H	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
ESR1	0	POLR2H	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED26	2	POLR2K	0	affinity chromatography technology	Takahashi H (2011)	1
GPN3	4	POLR2F	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015)	2
MED10	0	POLR2G	0	affinity chromatography technology	Sato S (2004)	1
MED19	1	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
ELOA	3	POLR2G	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
GPN3	4	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED26	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011), Takahashi H (2011)	4
XPO1	8	POLR2E	0	affinity chromatography technology	Kirli K (2015)	1
5430	0	POLR2H	0	pull down, pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Wu W (2007), Wan C (2015)	5
MED19	1	POLR2F	1	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
XPO1	8	POLR2C	0	affinity chromatography technology	Kirli K (2015)	1
CUL5	1	POLR2B	3	affinity chromatography technology	Bennett EJ (2010)	1
RECQL5	3	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Zheng L (2009), Ayguen O (2008)	2
LMO2	2	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
MED29	2	POLR2L	1	affinity chromatography technology	Sato S (2004)	1
5430	0	POLR2E	0	pull down, pull down, pull down, biochemical, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	6
RECQL5	3	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2017)	2
POLR2B	3	POLR2C	0	pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	5
5430	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Wan C (2015), Hein MY (2015)	4
RNGTT	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
MED10	0	MED19	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Tomomori-Sato C (2004), Sato S (2003), Zhang X (2005), Takahashi H (2011), Huttlin EL (2015), Huttlin EL (2017)	8
ESR1	0	POLR2E	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
PIH1D1	0	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ELOA	3	5430	0	imaging technique, imaging technique, enzymatic study	Zhang H (2006), Zhang H (2006), Yasukawa T (2008)	3
PIH1D1	0	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED26	2	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
POLR2C	0	POLR2E	0	pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	5
RNGTT	0	POLR2D	0	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
XPO1	8	POLR2G	0	affinity chromatography technology	Kirli K (2015)	1
SUPT5H	2	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
XPO1	8	SYDE1	4	affinity chromatography technology	Kirli K (2015)	1
RPRD1B	1	POLR2F	1	affinity chromatography technology	Huttlin EL (2015)	1
RPRD1B	1	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED29	2	POLR2E	0	affinity chromatography technology	Sato S (2004)	1
POLR2M	0	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PSMB9	0	POLR2F	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
SUPT5H	2	RPRD1B	1	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	SUPT5H	2	affinity chromatography technology, affinity chromatography technology	Bennett CB (2008), Bennett CB (2008)	2
POLR2M	0	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED10	0	MED26	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011)	3
POLR2D	0	POLR2E	0	pull down, biochemical, affinity chromatography technology	Schaller S (1999), Wan C (2015), Huttlin EL (2017)	3
XPO1	8	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
POLR2K	0	POLR2H	0	pull down, biochemical	Acker J (1997), Wan C (2015)	2
POLR2B	3	POLR2L	1	pull down, pull down, biochemical	Acker J (1997), Acker J (1997), Wan C (2015)	3
POLR2C	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015)	4
POLR2G	0	POLR2I	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
ESR1	0	POLR2F	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2E	0	POLR2I	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
ELOA	3	POLR2K	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2M	0	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DCUN1D1	0	CUL5	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
DCUN1D1	0	COPS5	0	affinity chromatography technology	Bennett EJ (2010)	1
SRC	2	POLR2K	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2E	0	SUPT5H	2	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
BRCA1	7	POLR2G	0	affinity chromatography technology	Woods NT (2012)	1
POLR2M	0	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
GPN3	4	POLR1B	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	POLR2G	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
ELOA	3	POLR2L	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED10	0	POLR2B	3	affinity chromatography technology	Sato S (2004)	1
ESR1	0	MED21	1	pull down	Kang YK (2002)	1
MED29	2	MED21	1	affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Sato S (2004), Zhang X (2005), Havugimana PC (2012), Huttlin EL (2017)	4
ESR1	0	POLR2I	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2B	3	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
5430	0	PCIF1	0	pull down, affinity chromatography technology, affinity chromatography technology	Fan H (2003), Fan H (2003), Hein MY (2015)	3
GPN3	4	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED29	2	POLR2H	0	affinity chromatography technology	Sato S (2004)	1
POLR2G	0	POLR2H	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Hein MY (2015), Huttlin EL (2017)	4
MED26	2	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
CPNE2	2	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
SUPT5H	2	POLR2L	1	affinity chromatography technology	Hein MY (2015)	1
XPO1	8	POLR2K	0	affinity chromatography technology	Kirli K (2015)	1
POLR2C	0	SUPT5H	2	affinity chromatography technology, biochemical, affinity chromatography technology	Ayguen O (2008), Wan C (2015), Hein MY (2015)	3
MED26	2	MED21	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2017)	3
MED19	1	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
CPNE2	2	POLR2D	0	affinity chromatography technology	Huttlin EL (2017)	1
POLR2B	3	POLR2H	0	pull down, pull down, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Jeronimo C (2007), Wan C (2015)	4
POLR2L	1	POLR2H	0	pull down, biochemical	Acker J (1997), Wan C (2015)	2
BRCA1	7	POLR2D	0	affinity chromatography technology	Woods NT (2012)	1
POLR2B	3	POLR2F	1	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
WDR48	2	POLR2I	0	affinity chromatography technology	Sowa ME (2009)	1
SYDE1	4	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
ELOA	3	POLR2B	3	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
ESR1	0	POLR2B	3	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
PSMB9	0	POLR2E	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
PSMB9	0	POLR2G	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
SRC	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, imaging technique, imaging technique, imaging technique, pull down, imaging technique, imaging technique, affinity chromatography technology, two hybrid	Migliaccio A (2000), Teo AK (2001), Slentz-Kesler K (2000), Bourdoncle A (2005), Jaber BM (2004), Jaber BM (2004), Ku TK (2007), Cabodi S (2004), Monroe DG (2003), Hitosugi T (2007), Zwart W (2007), Zwart W (2007), Zwart W (2007), Yoshimaru T (2013), Yoshimaru T (2013), Zhang H (2006), Zhang H (2006), Zhang H (2006), Endler A (2012), Endler A (2012)	20
ESR1	0	POLR2C	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
ESR1	0	MED10	0	affinity chromatography technology, pull down	Kang YK (2002), Kang YK (2002)	2
CUL5	1	POLR2D	0	affinity chromatography technology	Bennett EJ (2010)	1
GPN3	4	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MYC	2	5430	0	affinity chromatography technology	Koch HB (2007)	1
MED19	1	POLR2K	0	affinity chromatography technology	Takahashi H (2011)	1
RECQL5	3	POLR2I	0	affinity chromatography technology	Ayguen O (2008)	1
MYC	2	POLR2B	3	affinity chromatography technology	Koch HB (2007)	1
LMO2	2	GPN3	4	affinity chromatography technology	Huttlin EL (2017)	1
PSMB9	0	5430	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
WDR48	2	POLR2G	0	affinity chromatography technology	Sowa ME (2009)	1
RECQL5	3	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2017)	2
PIH1D1	0	UXT	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RNGTT	0	POLR2B	3	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
SUPT5H	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Kim JB (1999), Wada T (1998), Kang H (2011), Kang H (2011), Havugimana PC (2012), Yamaguchi Y (2002), Yamaguchi Y (1999), Yamaguchi Y (1999), Bennett CB (2008), Wan C (2015), Hein MY (2015)	11
POLR2M	0	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPRD1B	1	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	POLR2B	3	affinity chromatography technology, genetic interference	Kirli K (2015), Horlbeck MA (2018)	2
POLR2I	0	TBCD	4	two hybrid	Wang J (2011)	1
POLR2M	0	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	POLR2C	0	affinity chromatography technology	Woods NT (2012)	1
POLR2M	0	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LMO2	2	POLR2C	0	affinity chromatography technology	Huttlin EL (2017)	1
POLR2K	0	POLR2B	3	pull down, biochemical	Acker J (1997), Wan C (2015)	2
BRCA1	7	GPN3	4	affinity chromatography technology	Woods NT (2012)	1
LMO2	2	RECQL5	3	affinity chromatography technology	Huttlin EL (2017)	1
MED29	2	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Hein MY (2015)	2
SUPT5H	2	POLR2D	0	affinity chromatography technology	Hein MY (2015)	1
ELOA	3	CUL5	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Weems JC (2015), Weems JC (2015), Weems JC (2015)	3
ESR1	0	POLR2G	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2F	1	POLR2I	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
LMO2	2	POLR2G	0	affinity chromatography technology	Huttlin EL (2017)	1
MED10	0	MED29	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sato S (2004), Sato S (2004), Tomomori-Sato C (2004), Sato S (2003), Wan C (2015)	5
POLR1B	2	POLR2I	0	biochemical	Wan C (2015)	1
POLR2F	1	RECQL5	3	affinity chromatography technology	Hein MY (2015)	1
MED26	2	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
POLR2M	0	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2D	0	POLR2C	0	pull down, biochemical, affinity chromatography technology, biochemical	Schaller S (1999), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	4
RNGTT	0	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
POLR2D	0	POLR2B	3	pull down, biochemical, biochemical, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	4
LMO2	2	POLR2E	0	affinity chromatography technology	Huttlin EL (2017)	1
SYDE1	4	POLR2D	0	affinity chromatography technology	Huttlin EL (2017)	1
LMO2	2	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
PIH1D1	0	POLR2B	3	affinity chromatography technology	Huttlin EL (2017)	1
XPO1	8	POLR2I	0	affinity chromatography technology	Kirli K (2015)	1
PIH1D1	0	POLR2M	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED29	2	POLR2C	0	affinity chromatography technology	Sato S (2004)	1
RPRD1B	1	POLR2L	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SRC	2	POLR2I	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
COPS5	0	POLR2E	0	affinity chromatography technology	Bennett EJ (2010)	1
MED19	1	MED21	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2015), Huttlin EL (2017)	4
MED19	1	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
POLR2F	1	POLR1B	2	affinity chromatography technology	Hein MY (2015)	1
ESR1	0	5430	0	affinity chromatography technology, imaging technique, imaging technique, pull down	Ambrosino C (2010), Zhang H (2006), Zhang H (2006), Nalvarte I (2010)	4
BRCA1	7	POLR2M	0	affinity chromatography technology	Woods NT (2012)	1
ELOA	3	POLR2H	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2E	0	POLR2H	0	pull down, pull down, biochemical, biochemical	Acker J (1997), Acker J (1997), Kristensen AR (2012), Wan C (2015)	4
MED26	2	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	5
GPN3	4	POLR2M	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	RNGTT	0	affinity chromatography technology	Woods NT (2012)	1
POLR2D	0	5430	0	pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Wan C (2015), Zhao DY (2016), Huttlin EL (2017)	5
POLR2K	0	5430	0	pull down, biochemical	Acker J (1997), Wan C (2015)	2
5430	0	POLR2I	0	pull down, biochemical, biochemical	Knuesel MT (2009), Havugimana PC (2012), Wan C (2015)	3
ELOA	3	MED26	2	affinity chromatography technology	Takahashi H (2011)	1
BRCA1	7	ESR1	0	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zheng L (2001), Fan S (2001), Fan S (2001), Kawai H (2002), Fan S (2002), Fan S (2002), Nakuci E (2006), Wang C (2005), Wang C (2005), Dizin E (2010), Dizin E (2010), Ma Y (2010), Ma Y (2010), Fan S (2001), Ma YX (2005), Ma YX (2005), Ma YX (2005), Ma Y (2007), Ma Y (2007), Kawai H (2002), Jung YS (2014), Kawai H (2002), Kawai H (2002)	23
POLR2D	0	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
5430	0	MED21	1	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Scully R (1997), Cho H (1998), Cho H (1998), Sune C (1997), Huttlin EL (2017)	6
RECQL5	3	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Zheng L (2009), Ayguen O (2008), Ayguen O (2008), Ayguen O (2008), Ayguen O (2008), Urban V (2016), Kanagaraj R (2010), Kanagaraj R (2010), Li M (2011)	9
5430	0	POLR2L	1	pull down, pull down, biochemical	Acker J (1997), Acker J (1997), Wan C (2015)	3
RPRD1B	1	GPN3	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ELOA	3	POLR2D	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2E	0	GPN3	4	affinity chromatography technology	Huttlin EL (2017)	1
PSMB9	0	POLR2D	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
MED26	2	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
RPRD1B	1	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED26	2	POLR2H	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
POLR2K	0	POLR2F	1	pull down, biochemical	Acker J (1997), Wan C (2015)	2
MED26	2	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
ESR1	0	POLR2L	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR2E	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
POLR1B	2	POLR2L	1	biochemical	Wan C (2015)	1
POLR2L	1	POLR2I	0	biochemical	Wan C (2015)	1
COPS5	0	POLR2C	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	GPN3	4	affinity chromatography technology	Bennett EJ (2010)	1
PIH1D1	0	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RECQL5	3	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
WDR48	2	BRCA1	7	affinity chromatography technology	Sowa ME (2009)	1
POLR2M	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RNGTT	0	5430	0	affinity chromatography technology	St-Denis N (2016)	1
BRCA1	7	RECQL5	3	affinity chromatography technology	Woods NT (2012)	1
MED10	0	POLR2H	0	affinity chromatography technology	Sato S (2004)	1
SRC	2	POLR2L	1	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
POLR1B	2	POLR2E	0	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
ESR1	0	POLR2K	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
BRCA1	7	POLR2E	0	affinity chromatography technology	Woods NT (2012)	1
SRC	2	POLR2D	0	imaging technique, imaging technique	Zhang H (2006), Zhang H (2006)	2
DCUN1D1	0	5430	0	affinity chromatography technology	Bennett EJ (2010)	1
GPN3	4	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED10	0	POLR2C	0	affinity chromatography technology	Sato S (2004)	1
RPRD1B	1	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	POLR2B	3	pull down, biochemical, biochemical	Knuesel MT (2009), Havugimana PC (2012), Wan C (2015)	3
ELOA	3	BRCA1	7	two hybrid	Hill SJ (2014)	1
MED29	2	5430	0	affinity chromatography technology	Sato S (2004)	1