PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NUP62	1	KRT20	2	two hybrid	Rolland T (2014)	1
84832	0	KRTAP10-7	0	two hybrid	Rolland T (2014)	1
KRT20	2	USHBP1	1	two hybrid	Rolland T (2014)	1
KRT20	2	KRTAP10-9	1	two hybrid	Rolland T (2014)	1
KRT15	2	KRT20	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KRT15	2	EXOC8	1	two hybrid	Rual JF (2005)	1
EIF4E2	2	PLEKHA5	2	affinity chromatography technology	Boldt K (2016)	1
KRTAP10-9	1	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
USHBP1	1	EXOC8	1	two hybrid, affinity chromatography technology	Rual JF (2005), Rual JF (2005)	2
KRT15	2	USHBP1	1	two hybrid	Rual JF (2005)	1
KRT15	2	84832	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KRT20	2	KRT20	2	two hybrid	Rual JF (2005)	1
KRT15	2	AMOTL2	5	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
FXR2	2	CCDC85B	0	two hybrid	Rual JF (2005)	1
USHBP1	1	KRT40	0	two hybrid	Rolland T (2014)	1
PLEKHA5	2	KRT20	2	two hybrid	Bandyopadhyay S (2010)	1
KRT13	2	AMOTL2	5	two hybrid	Rolland T (2014)	1
EIF4E2	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
AMOTL2	5	KRT20	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CCDC85B	0	ZC2HC1C	0	two hybrid	Rual JF (2005)	1
NUP62	1	TXLNA	3	two hybrid	Rolland T (2014)	1
EIF4E2	2	USHBP1	1	two hybrid	Rolland T (2014)	1
FXR2	2	AMOTL2	5	two hybrid	Rual JF (2005)	1
KRT20	2	KRT40	0	two hybrid	Rolland T (2014)	1
KRT20	2	ZC3H14	3	two hybrid	Rual JF (2005)	1
KRT20	2	KRT80	1	two hybrid	Rolland T (2014)	1
USHBP1	1	84832	0	two hybrid	Rolland T (2014)	1
KRT13	2	KRT20	2	two hybrid	Rolland T (2014)	1
FXR2	2	KRT20	2	two hybrid	Rual JF (2005)	1
PRC1	4	CCDC85B	0	two hybrid	Rual JF (2005)	1
TFIP11	5	TXLNA	3	two hybrid	Rolland T (2014)	1
ABI2	4	KRT20	2	two hybrid	Rual JF (2005)	1
KRT20	2	EXOC8	1	two hybrid	Rual JF (2005)	1
PIK3R2	3	KRT20	2	two hybrid	Rolland T (2014)	1
EIF4E2	2	KRTAP10-9	1	two hybrid	Rolland T (2014)	1
PRC1	4	KRT20	2	two hybrid	Rual JF (2005)	1
KRT13	2	84832	0	two hybrid	Rolland T (2014)	1
TFIP11	5	ZC2HC1C	0	two hybrid	Rolland T (2014)	1
EIF4E2	2	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
KRTAP10-7	0	KRTAP10-9	1	two hybrid	Rolland T (2014)	1
KRT20	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
KRTAP10-9	1	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
KRT40	0	TXLNA	3	two hybrid	Rolland T (2014)	1
KRT15	2	KRT80	1	two hybrid	Rolland T (2014)	1
ABI2	4	NUP62	1	two hybrid	Rolland T (2014)	1
ZC2HC1C	0	KRT40	0	two hybrid	Rolland T (2014)	1
EIF4E2	2	AMOTL2	5	two hybrid	Rolland T (2014)	1
KRT15	2	TXLNA	3	two hybrid	Rolland T (2014)	1
PRC1	4	USHBP1	1	two hybrid, two hybrid	Rual JF (2005), Xin X (2009)	2
KRT15	2	ZC2HC1C	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
VIM	0	KRT20	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KRT20	2	TXLNA	3	two hybrid	Rolland T (2014)	1
EIF4E2	2	KRT40	0	two hybrid	Rolland T (2014)	1
CCDC85B	0	EXOC8	1	two hybrid	Rual JF (2005)	1
KRT20	2	84832	0	two hybrid	Rual JF (2005)	1
KRT20	2	KRTAP10-7	0	two hybrid	Rolland T (2014)	1
EIF4E2	2	KRT20	2	two hybrid	Rual JF (2005)	1
KRT13	2	TXLNA	3	two hybrid	Rolland T (2014)	1
KRT20	2	ZC2HC1C	0	two hybrid	Rual JF (2005)	1
ABI2	4	TFIP11	5	two hybrid	Rolland T (2014)	1
KRT20	2	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
KRT13	2	EIF4E2	2	two hybrid	Rolland T (2014)	1
KRT13	2	ABI2	4	two hybrid	Rolland T (2014)	1
KRT20	2	C9orf16	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
TFIP11	5	KRT20	2	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
KRT15	2	ABI2	4	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
KRTAP10-7	0	KRTAP10-8	0	two hybrid	Rolland T (2014)	1
KRTAP10-7	0	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
84832	0	KRT40	0	two hybrid	Rolland T (2014)	1
PIK3R2	3	KRT15	2	affinity chromatography technology, two hybrid	Brehme M (2009), Rolland T (2014)	2
KRTAP10-8	0	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
KRT20	2	COASY	1	two hybrid	Rual JF (2005)	1
CCDC85B	0	KRT20	2	two hybrid	Rual JF (2005)	1
USHBP1	1	TXLNA	3	two hybrid	Rolland T (2014)	1