PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	CCT2	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
NXF1	0	CCT2	1	affinity chromatography technology	Castello A (2012)	1
RNF41	2	UBE2D3	1	pull down, pull down	Yu F (2008), Qiu XB (2004)	2
RPA1	0	ATP6V0D1	0	affinity chromatography technology	Marechal A (2014)	1
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
ELAVL1	0	UBE2D3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
UBE2D1	0	RFWD3	5	two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009)	2
TP53	0	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Romanova LY (2004), Romanova LY (2004), Riva F (2001), Glanzer JG (2013)	4
TCP1	0	CCT2	1	affinity chromatography technology, biochemical, biochemical, biochemical, biochemical	Gingras AC (2005), Imai Y (2003), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	5
PFDN1	0	PFDN2	1	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
RPA3	2	RAD51	3	two hybrid	Du Y (2009)	1
RPA3	2	RPA2	0	biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
HSP90AA1	7	UBE2N	1	pull down	Zhang M (2005)	1
CAMK1G	3	RFWD3	5	affinity chromatography technology	Huttlin EL (2017)	1
LGR4	3	HSPD1	0	affinity chromatography technology	Carmon KS (2014)	1
CCT2	1	CCT3	1	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
NXF1	0	RAD51	3	two hybrid	Wang J (2011)	1
RFWD3	5	CCT8	0	affinity chromatography technology	Hein MY (2015)	1
MOV10	6	RFWD3	5	affinity chromatography technology	Castello A (2012)	1
RFWD3	5	LYAR	0	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	HSP90B1	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Miyamoto-Sato E (2010), Wu B (2015), Wu B (2015), Wu B (2015), Wu B (2015)	5
RFWD3	5	PFDN1	0	affinity chromatography technology	Hein MY (2015)	1
RPA1	0	RPA2	0	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017)	13
RFWD3	5	PFDN2	1	affinity chromatography technology	Hein MY (2015)	1
DNAJB2	0	RFWD3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBIP	0	RFWD3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UBE2D2	0	RFWD3	5	two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009)	2
HSP90AA1	7	RFWD3	5	affinity chromatography technology	Taipale M (2012)	1
UBE2E1	1	RFWD3	5	two hybrid	Markson G (2009)	1
UBE2W	0	RFWD3	5	two hybrid	Markson G (2009)	1
RFWD3	5	CANX	4	affinity chromatography technology	Hein MY (2015)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
TCP1	0	CCT4	2	affinity chromatography technology, biochemical, biochemical, biochemical	Gingras AC (2005), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	4
UBE2D4	0	RFWD3	5	two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009)	2
RFWD3	5	COA1	0	affinity chromatography technology	Gong Z (2011)	1
CCT8	0	CCT6A	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
RFWD3	5	GLG1	0	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	UBE2N	1	pull down	David Y (2011)	1
RAD51	3	HSP90AA1	7	two hybrid	Arroyo R (2015)	1
TP53	0	RPA2	0	affinity chromatography technology	Li X (2015)	1
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
RFWD3	5	RPA3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Liu S (2011), Gong Z (2011), Gong Z (2011), Marechal A (2014), Inano S (2017), Kwasna D (2018)	6
TP53	0	CCT7	2	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
CCT5	1	XPO1	8	biochemical	Havugimana PC (2012)	1
RFWD3	5	CCT2	1	affinity chromatography technology	Hein MY (2015)	1
CCT4	2	CCT3	1	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
RPA2	0	CANX	4	affinity chromatography technology	Marechal A (2014)	1
CCT2	1	HSP90B1	3	pull down	Lin YF (2012)	1
CCT5	1	CCT7	2	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
RFWD3	5	ATP6V0D1	0	affinity chromatography technology	Hein MY (2015)	1
RFWD3	5	RAD51	3	enzymatic study, affinity chromatography technology, pull down, two hybrid, unspecified method	Inano S (2017), Inano S (2017), Inano S (2017), Inano S (2017), Inano S (2017)	5
ELAVL1	0	XPO1	8	affinity chromatography technology	Abdelmohsen K (2009)	1
CCT3	1	CCT8	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
CCT2	1	CCT4	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
NXF1	0	XPO1	8	affinity chromatography technology	Bachi A (2000)	1
XPO1	8	CEP170	4	affinity chromatography technology	Kirli K (2015)	1
TP53	0	CCT3	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
NXF1	0	FBXW7	2	affinity chromatography technology	Castello A (2012)	1
CCT5	1	CCT6A	1	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
RFWD3	5	HSP90B1	3	affinity chromatography technology	Hein MY (2015)	1
RPA2	0	MOV10	6	affinity chromatography technology	Marechal A (2014)	1
RPA3	2	MOV10	6	affinity chromatography technology	Marechal A (2014)	1
TCP1	0	CCT5	1	affinity chromatography technology, biochemical, biochemical	Gingras AC (2005), Havugimana PC (2012), Wan C (2015)	3
HSPD1	0	APP	1	affinity chromatography technology, pull down	Kumar P (2007), Olah J (2011)	2
CCT4	2	XPO1	8	biochemical	Havugimana PC (2012)	1
CCT5	1	CCT8	0	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
CCT7	2	CCT6A	1	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
HSP90AA1	7	TCP1	0	affinity chromatography technology	Falsone SF (2005)	1
UBE2D3	1	RFWD3	5	two hybrid, two hybrid	van Wijk SJ (2009), Markson G (2009)	2
CEP170	4	RFWD3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ELAVL1	0	RNF41	2	affinity chromatography technology	Abdelmohsen K (2009)	1
CCT2	1	CCT7	2	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
CCT4	2	CCT5	1	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
TPH1	1	APP	1	pull down	Olah J (2011)	1
TCP1	0	CCT7	2	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology	Gingras AC (2005), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	5
BBS7	2	RFWD3	5	affinity chromatography technology	Huttlin EL (2017)	1
TCP1	0	CCT6A	1	affinity chromatography technology, biochemical, biochemical	Gingras AC (2005), Havugimana PC (2012), Wan C (2015)	3
MDM2	2	UBE2E3	0	pull down, pull down	David Y (2011), Yamauchi T (2014)	2
CCT3	1	CCT7	2	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
CCT2	1	CCT8	0	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
NXF1	0	CCT7	2	affinity chromatography technology	Castello A (2012)	1
RFWD3	5	RPA2	0	imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Liu S (2011), Liu S (2011), Liu S (2011), Gong Z (2011), Gong Z (2011), Gong Z (2011), Marechal A (2014), Elia AE (2015), Feeney L (2017), Inano S (2017), Kwasna D (2018)	11
MBNL1	3	APP	1	pull down	Olah J (2011)	1
ELAVL1	0	UBE2N	1	affinity chromatography technology	Abdelmohsen K (2009)	1
MOV10	6	HYOU1	2	affinity chromatography technology	Castello A (2012)	1
CCT8	0	APP	1	pull down	Olah J (2011)	1
XPO1	8	RFWD3	5	affinity chromatography technology	Kirli K (2015)	1
TP53	0	UBE2N	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Laine A (2006), Laine A (2006), Laine A (2006), Topisirovic I (2009), Topisirovic I (2009)	5
CCT2	1	HSP90AA1	7	affinity chromatography technology	Lin YF (2012)	1
CCT7	2	CCT8	0	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
HSP90AA1	7	FBXW7	2	affinity chromatography technology	Taipale M (2012)	1
RFWD3	5	MDM2	2	pull down, affinity chromatography technology	Fu X (2010), Fu X (2010)	2
HSP90B1	3	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Wu B (2015), Wu B (2015), Wu B (2015), Wu B (2015)	4
TP53	0	TCP1	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
RPA3	2	ELAVL1	0	affinity chromatography technology	Marechal A (2014)	1
RFWD3	5	CCT6A	1	affinity chromatography technology	Hein MY (2015)	1
HSP90AA1	7	CAMK1G	3	affinity chromatography technology	Taipale M (2012)	1
MDM2	2	UBE2D3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Yadavilli S (2009), Nie J (2010), Minsky N (2004), Wang X (2011), Sionov RV (2001), Oh W (2010), Zhu Y (2009), Latini P (2011), Jung CR (2010), David Y (2011), Ye B (2013), Cheng Q (2014), Saville MK (2004), Yamauchi T (2014), Jin M (2017)	15
TP53	0	MOV10	6	affinity chromatography technology	Li X (2015)	1
MDM2	2	CANX	4	unspecified method	Nicholson J (2014)	1
CCT2	1	CCT5	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
ELAVL1	0	UBE2W	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RAD51	3	RPA1	0	pull down, two hybrid	Sugiyama T (2002), Du Y (2009)	2
CANX	4	CCT6A	1	biochemical	Wan C (2015)	1
CCT4	2	CANX	4	biochemical	Wan C (2015)	1
RFWD3	5	CCT4	2	affinity chromatography technology	Hein MY (2015)	1
UBE2E3	0	RFWD3	5	two hybrid	Markson G (2009)	1
UBE2D1	0	MDM2	2	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Singh RK (2007), Poyurovsky MV (2007), Li M (2003), Yogosawa S (2003), Honda R (1997), Sun XX (2011), Singh RK (2007), Taira N (2010), Fu X (2010), Wang KS (2011), Wang X (2004), Sehat B (2008), Wawrzynow B (2007), Burch L (2004), Frazier DP (2012), Huart AS (2012), Pettersson S (2009), Gama V (2009), Demma M (2010), Chymkowitch P (2011), Yan C (2010), Yang Y (2013), Ranaweera RS (2013), Siepe D (2009), Shi D (2009), Uchiki T (2009), Grossman SR (2003), Xirodimas DP (2004), Saville MK (2004), Liu T (2015), Batuello CN (2015), Fraser JA (2015), Yamauchi T (2014), Liu D (2016), McClurg UL (2016), Landre V (2017)	36
CCT4	2	CCT7	2	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
CANX	4	CCT3	1	biochemical	Wan C (2015)	1
RFWD3	5	HYOU1	2	affinity chromatography technology	Hein MY (2015)	1
FBXW7	2	CCT3	1	affinity chromatography technology	Kourtis N (2015)	1
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
TP53	0	CCT6A	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
RFWD3	5	HSPD1	0	affinity chromatography technology	Hein MY (2015)	1
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
RPA3	2	ATP6V0D1	0	affinity chromatography technology	Marechal A (2014)	1
MOV10	6	HSPD1	0	affinity chromatography technology	Castello A (2012)	1
RPA3	2	RPA1	0	biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015)	8
CCT3	1	CCT6A	1	biochemical, biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	4
CCT5	1	CCT3	1	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
MDM2	2	XPO1	8	affinity chromatography technology	Jacob AG (2014)	1
MOV10	6	CCT7	2	affinity chromatography technology	Castello A (2012)	1
RPA1	0	MOV10	6	affinity chromatography technology	Marechal A (2014)	1
TP53	0	CCT8	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
TPH1	1	RFWD3	5	affinity chromatography technology	Huttlin EL (2017)	1
CANX	4	HSP90B1	3	biochemical	Wan C (2015)	1
RFWD3	5	CCT5	1	affinity chromatography technology	Hein MY (2015)	1
FBXW7	2	RFWD3	5	genetic interference	Bailey ML (2015)	1
UBE2N	1	RFWD3	5	two hybrid	Markson G (2009)	1
RFWD3	5	TCP1	0	affinity chromatography technology	Hein MY (2015)	1
HSP90AA1	7	CANX	4	biochemical	Wan C (2015)	1
CCT3	1	HSP90B1	3	biochemical	Wan C (2015)	1
LGR4	3	RFWD3	5	affinity chromatography technology	Carmon KS (2014)	1
RFWD3	5	CCT3	1	affinity chromatography technology	Hein MY (2015)	1
RPA3	2	CANX	4	affinity chromatography technology	Marechal A (2014)	1
RFWD3	5	APP	1	pull down	Olah J (2011)	1
CCT5	1	TP53	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Fogeron ML (2013), Horikawa I (2014)	3
RFWD3	5	RPA1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Liu S (2011), Liu S (2011), Liu S (2011), Gong Z (2011), Gong Z (2011), Gong Z (2011), Marechal A (2014), Elia AE (2015), Feeney L (2017), Inano S (2017), Kwasna D (2018)	11
ELAVL1	0	RFWD3	5	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	PFDN2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
RPA1	0	CANX	4	affinity chromatography technology	Marechal A (2014)	1
RNF41	2	APP	1	pull down	Olah J (2011)	1
RFWD3	5	MBNL1	3	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	HSPD1	0	affinity chromatography technology	Castello A (2012)	1
RPA2	0	APP	1	pull down	Olah J (2011)	1
LGR4	3	CANX	4	affinity chromatography technology	Carmon KS (2014)	1
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
RPA1	0	ELAVL1	0	affinity chromatography technology	Marechal A (2014)	1
PIP4K2A	0	RFWD3	5	affinity chromatography technology	Huttlin EL (2017)	1
RPA2	0	ATP6V0D1	0	affinity chromatography technology	Marechal A (2014)	1
CCT7	2	APP	1	pull down	Olah J (2011)	1
RAD51	3	TP53	0	affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Stuerzbecher HW (1996), Stuerzbecher HW (1996), Buchhop S (1997), Nakai-Murakami C (2007), Yang Q (2004), Rasti M (2015), Rasti M (2015)	10
RPA2	0	PFDN2	1	biochemical	Kristensen AR (2012)	1
FBXW7	2	TP53	0	affinity chromatography technology	Huttlin EL (2017)	1
MDM2	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013)	33
NXF1	0	RFWD3	5	affinity chromatography technology	Castello A (2012)	1
CCT4	2	CCT6A	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
RPA2	0	ELAVL1	0	affinity chromatography technology	Marechal A (2014)	1
CCT2	1	CCT6A	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
TCP1	0	CCT8	0	affinity chromatography technology, biochemical, biochemical	Gingras AC (2005), Havugimana PC (2012), Wan C (2015)	3
RNF41	2	RFWD3	5	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	HYOU1	2	affinity chromatography technology	Castello A (2012)	1
NXF1	0	HSP90AA1	7	affinity chromatography technology	Castello A (2012)	1
TP53	0	CCT4	2	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
TCP1	0	CCT3	1	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology	Gingras AC (2005), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	5
TP53	0	RFWD3	5	affinity chromatography technology, pull down, affinity chromatography technology	Fu X (2010), Fu X (2010), Fu X (2010)	3
ELAVL1	0	CANX	4	affinity chromatography technology	Abdelmohsen K (2009)	1
MOV10	6	FBXW7	2	affinity chromatography technology	Castello A (2012)	1
RFWD3	5	CCT7	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
CCT4	2	CCT8	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2