PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TRIM25	5	PPP2R1B	4	affinity chromatography technology	Choudhury NR (2017)	1
PTTG1	0	ESPL1	2	affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Kim HS (2009), Hellmuth S (2014), Hellmuth S (2014), Huttlin EL (2015), Hein MY (2015), Voets E (2015), Huttlin EL (2017)	8
PPP2CA	7	PRR14	3	affinity chromatography technology, affinity chromatography technology	Glatter T (2009), Huttlin EL (2017)	2
PPP2R5D	29	55844	0	biochemical	Wan C (2015)	1
UBE2S	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Williamson A (2009), Brown NG (2014), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016)	7
PPP2R1A	8	PRR14	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glatter T (2009), Hein MY (2015), Huttlin EL (2017), Yadav L (2017)	4
NEK1	6	PPP2R5A	2	two hybrid	Surpili MJ (2003)	1
TRIM25	5	MYC	2	affinity chromatography technology	Choudhury NR (2017)	1
PPP2CA	7	DAPK1	6	enzymatic study, affinity chromatography technology	Widau RC (2010), Guenebeaud C (2010)	2
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
PPP2R5A	2	PTTG1	0	enzymatic study	Hellmuth S (2014)	1
TRIM25	5	AXIN1	1	affinity chromatography technology	Choudhury NR (2017)	1
BCL2	0	MYC	2	affinity chromatography technology, imaging technique	Jin Z (2004), Jin Z (2004)	2
FAM43A	0	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PPP2R5A	2	AXIN1	1	affinity chromatography technology, pull down, affinity chromatography technology	Yamamoto H (2001), Yamamoto H (2001), Arnold HK (2009)	3
CBX5	3	PPP2CA	7	affinity chromatography technology	Nozawa RS (2010)	1
PPP2R5D	29	PPP2R1B	4	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology	McCright B (1996), McCright B (1996), Sablina AA (2007), Havugimana PC (2012), Wallach T (2013), Wan C (2015), Hein MY (2015)	7
PPP2R1B	4	DAPK1	6	affinity chromatography technology	Guenebeaud C (2010)	1
TRIM25	5	PPP2CA	7	affinity chromatography technology	Choudhury NR (2017)	1
CDC27	2	PPP2CA	7	affinity chromatography technology	Craney A (2016)	1
PRR14	3	PPP2R5A	2	affinity chromatography technology	Huttlin EL (2017)	1
EIF2AK2	1	PPP2R5A	2	affinity chromatography technology	Xu Z (2000)	1
CTLA4	0	PPP2R5A	2	affinity chromatography technology, two hybrid	Baroja ML (2002), Baroja ML (2002)	2
CDC20	1	BUB1B	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Fang G (2002), Fang G (2002), Wu H (2000), Wu H (2000), Wu H (2000), Kallio MJ (2002), Sudakin V (2001), Sudakin V (2001), Skoufias DA (2001), Nilsson J (2008), Ho CY (2010), Ho CY (2010), Garnett MJ (2009), Hutchins JR (2010), Di Fiore B (2010), Di Fiore B (2010), Mansfeld J (2011), Jia L (2011), Braunstein I (2007), Eytan E (2008), Eytan E (2008), Ma HT (2011), Miniowitz-Shemtov S (2012), Tang Z (2001), Tang Z (2001), Tang Z (2001), Tang Z (2001), Bolanos-Garcia VM (2011), Ge S (2009), Liu L (2007), Westhorpe FG (2011), Westhorpe FG (2011), Kwan PS (2013), Tian W (2012), Tian W (2012), Tian W (2012), Santaguida S (2011), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Han JS (2014), Izawa D (2014), Hein JB (2014), So J (2015), Scialpi F (2015), Scialpi F (2015), Diaz-Martinez LA (2015), Diaz-Martinez LA (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Voets E (2015), Chen TC (2014), Lischetti T (2014), Lischetti T (2014), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Huttlin EL (2017), Izawa D (2012), Jia L (2016), Jia L (2016), Hein JB (2016), Kaisari S (2017)	73
PPP2CB	1	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Glatter T (2009), Fogeron ML (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), St-Denis N (2016), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017)	15
PPP2R1B	4	PPP2CB	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhou J (2003), Zhou J (2003), Glatter T (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	7
PPP2R5A	2	UBE2S	2	affinity chromatography technology	Craney A (2016)	1
PPP2R5A	2	PPP2R1B	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical	Goudreault M (2009), Zhou J (2003), Zhou J (2003), McCright B (1996), McCright B (1996)	5
55844	0	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Glatter T (2009), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	4
55844	0	DAPK1	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Widau RC (2010), Widau RC (2010), Widau RC (2010)	3
MYC	2	PPP2R5A	2	affinity chromatography technology	Arnold HK (2009)	1
CDC27	2	PPP2R5A	2	affinity chromatography technology	Craney A (2016)	1
PPP2CB	1	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), St-Denis N (2016), Huttlin EL (2017)	3
BUB1B	0	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Lara-Gonzalez P (2011), Mansfeld J (2011), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Eytan E (2013), Wang K (2014), Han JS (2014), Han JS (2014), Lara-Gonzalez P (2011), So J (2015), Boekhout M (2015), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
FAM43A	0	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WNT3A	0	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AXIN1	1	PPP2CA	7	affinity chromatography technology	Arnold HK (2009)	1
PPP2CA	7	PPP2R1B	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Sablina AA (2007), Sablina AA (2007), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Yadav L (2017)	10
CDC20	1	PPP2R1A	8	affinity chromatography technology	Craney A (2016)	1
PPP2R5A	2	DAPK1	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Widau RC (2010), Widau RC (2010), Widau RC (2010)	3
PPP2R5A	2	PPP2R5C	3	affinity chromatography technology	Strack S (2002)	1
PTTG1	0	CDC27	2	affinity chromatography technology, pull down, pull down	Jeganathan KB (2006), Miller JJ (2006), Qiao R (2016)	3
PPP2R5C	3	PPP2R1B	4	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	McCright B (1996), McCright B (1996), Sablina AA (2007), Wan C (2015)	4
PPP2CA	7	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Goudreault M (2009), McCright B (1996), McCright B (1996), Widau RC (2010), Wan C (2015), Hein MY (2015), Craney A (2016), St-Denis N (2016), Yadav L (2017)	10
ESPL1	2	PPP2CA	7	biochemical	Hellmuth S (2014)	1
BCL2	0	PPP2R5A	2	affinity chromatography technology	Ruvolo PP (2002)	1
WNT3A	0	55844	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CBX5	3	PPP2R5A	2	affinity chromatography technology	Nozawa RS (2010)	1
APC	5	PPP2R5A	2	imaging technique	Galea MA (2001)	1
WNT3A	0	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTTG1	0	BUB1B	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Kim HS (2009), Kim HS (2009), Kim HS (2009), Kim HS (2009), Horlbeck MA (2018)	5
55844	0	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Widau RC (2010), Widau RC (2010)	2
PPP2CA	7	BCL2	0	enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Deng X (1998), Deng X (1998), Deng X (1998), Tamura Y (2004), Tamura Y (2004)	5
MOS	1	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRR14	3	PPP2R5C	3	affinity chromatography technology	Huttlin EL (2017)	1
AXIN1	1	APC	5	pull down, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Hino S (2005), Kitagawa M (1999), Sue Ng S (2010), Tran H (2012), Li VS (2012), Hein MY (2015), Hein MY (2015), Novellasdemunt L (2017)	12
CDC20	1	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Craney A (2016), Craney A (2016), Craney A (2016)	3
CBX5	3	PPP2CB	1	affinity chromatography technology	Nozawa RS (2010)	1
PPP2R1A	8	PTTG1	0	genetic interference	Horlbeck MA (2018)	1
CHEK2	2	PPP2R1A	8	affinity chromatography technology	Dozier C (2004)	1
ESPL1	2	PPP2R1A	8	biochemical	Hellmuth S (2014)	1
PTTG1	0	55844	0	two hybrid, pull down, affinity chromatography technology, enzymatic study	Gil-Bernabe AM (2006), Gil-Bernabe AM (2006), Gil-Bernabe AM (2006), Gil-Bernabe AM (2006)	4
PRR14	3	PPP2R5D	29	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	UBE2S	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Choudhury NR (2017)	2
CHEK2	2	PPP2R5D	29	two hybrid, pull down	Dozier C (2004), Dozier C (2004)	2
PPP2R1A	8	PPP2R5C	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Glatter T (2009), Dozier C (2004), Fogeron ML (2013), Wan C (2015), Hein MY (2015), Boldt K (2016), Shouse GP (2011), Yadav L (2017), Yadav L (2017)	10
CHEK2	2	PPP2R5C	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Dozier C (2004), Dozier C (2004), Dozier C (2004), Dozier C (2004), Dozier C (2004), Dozier C (2004)	6
PRR14	3	PPP2R1B	4	affinity chromatography technology	Huttlin EL (2017)	1
PPP2CA	7	PPP2R5C	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito A (2000), Goudreault M (2009), McCright B (1996), McCright B (1996), Glatter T (2009), Dozier C (2004), Letourneux C (2006), Wan C (2015), St-Denis N (2016), Shouse GP (2011), Shouse GP (2011), Yadav L (2017)	12
CDC20	1	PPP2CB	1	affinity chromatography technology	Craney A (2016)	1
PPP2CB	1	PPP2R5C	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glatter T (2009), Huttlin EL (2015), St-Denis N (2016), Huttlin EL (2017)	4
CDC20	1	PTTG1	0	enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Braunstein I (2007), Eytan E (2006), Pfleger CM (2001), Kim HS (2009), Kwan PS (2013), Tian W (2012), Van Voorhis VA (2014), Lara-Gonzalez P (2011), Wu T (2010), Izawa D (2014), Hellmuth S (2014), Wu T (2010), Shoji S (2014), Lara-Gonzalez P (2011), Di Fiore B (2015), Lee SB (2015), Qiao R (2016), Alfieri C (2016), Izawa D (2012), Jia L (2016)	20
BUB1B	0	APC	5	enzymatic study	Kaplan KB (2001)	1
55844	0	PPP2CB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Glatter T (2009), Glatter T (2009), Huttlin EL (2015), Wan C (2015), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	8
TRIM25	5	PPP2R5C	3	affinity chromatography technology	Choudhury NR (2017)	1
FAM43A	0	PPP2R5D	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BUB1B	0	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
PPP2R5A	2	PPP2R5D	29	biochemical	Wan C (2015)	1
TRIM25	5	PPP2R5A	2	affinity chromatography technology	Choudhury NR (2017)	1
PPP2CB	1	PRR14	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glatter T (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CDC20	1	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology	Craney A (2016), Craney A (2016)	2
FAM43A	0	PPP2R5C	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PPP2CB	1	PPP2R5D	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Glatter T (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), St-Denis N (2016), Huttlin EL (2017)	7
TRIM25	5	PPP2CB	1	affinity chromatography technology	Choudhury NR (2017)	1
PPP2CA	7	55844	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Glatter T (2009), Glatter T (2009), Oberg EA (2012), Widau RC (2010), Wan C (2015), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	11
MYC	2	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Arnold HK (2009), Junttila MR (2007), Cianfanelli V (2015), Cianfanelli V (2015)	4
TRIM25	5	PPP2R1A	8	affinity chromatography technology	Choudhury NR (2017)	1
AXIN1	1	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down	Arnold HK (2009), Arnold HK (2009), Arnold HK (2009)	3
PPP2R1A	8	DAPK1	6	enzymatic study	Widau RC (2010)	1
PPP2R1A	8	PPP2R5D	29	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Glatter T (2009), Havugimana PC (2012), Fogeron ML (2013), Wallach T (2013), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016), Yadav L (2017), Yadav L (2017)	11
PPP2CB	1	PPP2CA	7	biochemical, affinity chromatography technology	Wan C (2015), St-Denis N (2016)	2
WNT3A	0	PPP2R5D	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ESPL1	2	PPP2R5A	2	biochemical	Hellmuth S (2014)	1
PPP2CA	7	PPP2R5D	29	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), McCright B (1996), McCright B (1996), Glatter T (2009), Wan C (2015), Hein MY (2015), Hein MY (2015), St-Denis N (2016), Yadav L (2017), Yadav L (2017)	10
CHEK2	2	PPP2R5A	2	two hybrid, pull down	Dozier C (2004), Dozier C (2004)	2
APC	5	TRIM25	5	two hybrid	Arroyo R (2015)	1
PPP2R1A	8	PPP2R1B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Goudreault M (2009), Sablina AA (2007), Fogeron ML (2013), Wan C (2015), Hein MY (2015)	5
PPP2R1A	8	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, bioid	Goudreault M (2009), Goudreault M (2009), Zhou J (2003), Zhou J (2003), Widau RC (2010), Wan C (2015), Hein MY (2015), Yadav L (2017), Yadav L (2017)	9
CHEK2	2	PPP2CA	7	affinity chromatography technology, enzymatic study	Dozier C (2004), Liang X (2006)	2
UBE2S	2	CDC27	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Williamson A (2009), Brown NG (2014), Kelly A (2014), Craney A (2016)	4
PPP2CA	7	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Goudreault M (2009), Goudreault M (2009), Zhou J (2003), Zhou J (2003), Glatter T (2009), Glatter T (2009), Sablina AA (2007), Sablina AA (2007), Kong M (2009), Kong M (2009), Shamay M (2012), Havugimana PC (2012), Junttila MR (2007), Junttila MR (2007), Nazarenko I (2007), Kristensen AR (2012), Fogeron ML (2013), Sablina AA (2010), Lee CW (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Cianfanelli V (2015), St-Denis N (2016), Bryant JC (1999), Shouse GP (2011), Yadav L (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	30
CBX5	3	PRR14	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Nozawa RS (2010), Huttlin EL (2017), Hauri S (2016)	4
PPP2R1A	8	55844	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Goudreault M (2009), Glatter T (2009), Glatter T (2009), Widau RC (2010), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017), Yadav L (2017)	12
PPP2R5A	2	BUB1B	0	affinity chromatography technology	Craney A (2016)	1