PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
TP53	0	COPS4	0	affinity chromatography technology	Bhansali M (2014)	1
COPS8	2	COPS7A	0	biochemical, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Huang X (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
CUL3	17	KPNA2	0	affinity chromatography technology	Bennett EJ (2010)	1
DPPA4	0	BTBD2	4	two hybrid	Vinayagam A (2011)	1
BTBD2	4	RBM48	1	two hybrid	Stelzl U (2005)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
COPS2	5	COPS4	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huang X (2005), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	8
CUL3	17	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
BTBD2	4	GAPDH	0	two hybrid	Stelzl U (2005)	1
BTBD2	4	PTN	0	two hybrid	Stelzl U (2005)	1
COPS8	2	COPS3	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Min KW (2005), Enchev RI (2010), Sharon M (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
COPS8	2	COPS2	5	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Yang X (2002), Huang X (2005), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
BTBD2	4	SETDB1	3	two hybrid	Stelzl U (2005)	1
BTBD2	4	EEF1A1	0	two hybrid	Stelzl U (2005)	1
BTBD2	4	UBR1	3	two hybrid	Stelzl U (2005)	1
COPS2	5	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang X (2005), Bennett EJ (2010), Olma MH (2009), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	6
COPS3	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Yang X (2002), Enchev RI (2010), Huang X (2005), Kapelari B (2000), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Rozen S (2015), Huttlin EL (2017)	13
RFWD2	0	BTBD2	4	affinity chromatography technology	Olma MH (2009)	1
C9orf78	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS8	2	BTBD2	4	affinity chromatography technology	Huttlin EL (2017)	1
COPS7A	0	BTBD2	4	affinity chromatography technology	Hein MY (2015)	1
TP53	0	SMAD2	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Tateossian H (2009), Lu D (2013), Chen TC (2014)	5
BTBD1	2	TOP1	1	two hybrid, pull down, affinity chromatography technology, two hybrid	Xu L (2002), Xu L (2002), Khurana B (2010), Khurana B (2010)	4
EEF1A1	0	GAPDH	0	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
TP53	0	TOP1	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Gobert C (1999), Mao Y (2002), Restle A (2008)	3
BTBD2	4	TLE1	6	two hybrid	Stelzl U (2005)	1
CUL3	17	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Maerki S (2009)	5
KPNA2	0	COPS4	0	biochemical	Kristensen AR (2012)	1
C9orf78	0	BTBD2	4	affinity chromatography technology	Huttlin EL (2015)	1
UBXN1	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
COPS4	0	BTBD2	4	affinity chromatography technology	Olma MH (2009)	1
CUL3	17	TOP1	1	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
COPS6	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
OSGIN1	1	BTBD2	4	affinity chromatography technology	Huttlin EL (2015)	1
SMAD2	5	BTBD2	4	two hybrid	Colland F (2004)	1
ZNF512B	2	BTBD2	4	two hybrid	Colland F (2004)	1
COPS5	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	KPNA2	0	affinity chromatography technology	Neganova I (2011)	1
UBXN1	0	BTBD2	4	affinity chromatography technology	Alexandru G (2008)	1
COPS5	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
RFWD2	0	COPS2	5	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
CUL3	17	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
BTBD2	4	COPS6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	5
BTBD2	4	IGSF21	1	two hybrid	Stelzl U (2005)	1
BTBD2	4	CRMP1	0	two hybrid	Stelzl U (2005)	1
RFWD2	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
SMAD2	5	COPS5	0	two hybrid	Colland F (2004)	1
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
COPS2	5	TP53	0	affinity chromatography technology	Huang X (2005)	1
CDK2	0	GAPDH	0	affinity chromatography technology	Neganova I (2011)	1
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
CDK2	0	SMAD2	5	enzymatic study	Matsuura I (2004)	1
COPS2	5	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
RFWD2	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
BRD7	2	TP53	0	affinity chromatography technology, pull down, imaging technique	Drost J (2010), Drost J (2010), Drost J (2010)	3
CUL3	17	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
RFWD2	0	COPS8	2	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
TP53	0	EEF1A1	0	affinity chromatography technology	Fogeron ML (2013)	1
RFWD2	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS5	0	TOP1	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
BTBD2	4	UNC119	4	two hybrid	Stelzl U (2005)	1
BTBD1	2	BTBD2	4	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
BTBD2	4	BRD7	2	two hybrid	Stelzl U (2005)	1
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
BTBD2	4	GBP2	0	two hybrid	Stelzl U (2005)	1
COPS6	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	6
CUL3	17	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Wimuttisuk W (2014), Maerki S (2009), Huttlin EL (2017)	6
BTBD2	4	KPNA2	0	two hybrid	Wang J (2011)	1
COPS8	2	COPS5	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Olma MH (2009), Asare Y (2013), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016)	9
COPS5	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Fang L (2008), Enchev RI (2010), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Asare Y (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	13
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
CUL3	17	COPS8	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Schumacher FR (2015)	2
RFWD2	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Choi HH (2011), Choi HH (2011)	4
CDK2	0	EEF1A1	0	affinity chromatography technology	Neganova I (2011)	1
COPS8	2	BTBD1	2	affinity chromatography technology	Huttlin EL (2017)	1
COPS8	2	COPS6	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
CDK2	0	TOP1	1	affinity chromatography technology	Neganova I (2011)	1
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
OSGIN1	1	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	GAPDH	0	affinity chromatography technology	Sen N (2008)	1
COPS4	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	3
UBXN1	0	UBR1	3	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008)	2
UBXN1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008)	2
COPS2	5	BTBD2	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
COPS5	0	KPNA2	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
COPS3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
BTBD2	4	TOP1	1	two hybrid, pull down, affinity chromatography technology, two hybrid	Xu L (2002), Xu L (2002), Khurana B (2010), Khurana B (2010)	4
BTBD2	4	CCDC90B	2	two hybrid	Stelzl U (2005)	1
RFWD2	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dornan D (2006), Dornan D (2004), Dornan D (2004), Dornan D (2004), Dornan D (2004), Choi HH (2011), Yamada T (2013), Zou S (2016)	8
CUL3	17	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS3	1	BTBD2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
SMAD2	5	EEF1A1	0	two hybrid	Colland F (2004)	1
COPS7A	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
BTBD2	4	GDF9	2	two hybrid	Stelzl U (2005)	1
COPS6	0	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
BTBD2	4	TP53	0	two hybrid, affinity chromatography technology	Stelzl U (2005), Stelzl U (2005)	2
BTBD2	4	ERG28	0	two hybrid	Stelzl U (2005)	1
COPS8	2	COPS4	0	biochemical, affinity chromatography technology, biochemical, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
BTBD2	4	CDK2	0	two hybrid	Wang J (2011)	1