PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PEX19	2	PEX26	1	unspecified method	Schueller N (2010)	1
ELAVL1	0	PEX19	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	PEX26	1	affinity chromatography technology	Abdelmohsen K (2009)	1
PEX1	3	PEX6	3	pull down, pull down, two hybrid, pull down	Tamura S (1998), Tamura S (1998), Geisbrecht BV (1998), Geisbrecht BV (1998)	4
SUFU	2	PEX26	1	two hybrid, affinity chromatography technology	Rual JF (2005), Rual JF (2005)	2
PEX26	1	PEX1	3	affinity chromatography technology, pull down	Matsumoto N (2003), Matsumoto N (2003)	2
PEX26	1	PEX6	3	affinity chromatography technology, pull down	Matsumoto N (2003), Matsumoto N (2003)	2