PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RASSF1	3	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	MAPK14	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, fluorescent resonance energy transfe	Sanz-Moreno V (2003), Raingeaud J (1996), Stein B (1996), Chen Z (2001), Casar B (2007), Xia Y (1998), ter Haar E (2007), Ivanov AA (2017)	8
TRAF6	0	MAP2K6	2	affinity chromatography technology	Lin J (2015)	1
CCND2	2	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK14	0	SMAD7	1	affinity chromatography technology, affinity chromatography technology	Edlund S (2003), Zhang S (2006)	2
BRAF	12	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PLCB2	0	MAP2K3	1	two hybrid, affinity chromatography technology	Barr AJ (2002), Barr AJ (2002)	2
LRRK2	5	AKT1	1	enzymatic study, pull down	Ohta E (2011), Ohta E (2011)	2
MAPK14	0	MAPK1	1	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology	Sanz-Moreno V (2003), Tanoue T (2001), Srivastav RK (2011), Chan PM (2008)	4
TRAF6	0	RACK1	2	affinity chromatography technology	Lin J (2015)	1
TAOK2	8	MAP2K3	1	enzymatic study, affinity chromatography technology, imaging technique	Chen Z (2001), Chen Z (2001), Chen TC (2014)	3
RASSF1	3	RELA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	MAP2K6	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PKN1	4	MAP2K6	2	affinity chromatography technology	Takahashi M (2003)	1
MAP2K6	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K7	2	MAP2K4	3	enzymatic study, affinity chromatography technology	Ge B (2003), Li MG (2003)	2
LRRK2	5	MAP2K6	2	enzymatic study, affinity chromatography technology, enzymatic study	Gloeckner CJ (2009), Hsu CH (2010), Hsu CH (2010)	3
MAP2K6	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	MAP2K6	2	affinity chromatography technology	Crockett DK (2005)	1
BRAF	12	MAPK1	1	enzymatic study, genetic interference, enzymatic study	Ren JG (2008), Hart T (2015), Smith BD (2015)	3
MAP3K4	1	MAP2K6	2	enzymatic study, enzymatic study, two hybrid, pull down, enzymatic study, enzymatic study, imaging technique	Chan-Hui PY (1998), Abell AN (2005), Takekawa M (2005), Takekawa M (2005), Takekawa M (2005), Abell AN (2007), Chen TC (2014)	7
BECN1	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	TRAF6	0	affinity chromatography technology, enzymatic study	Shi CS (2010), Shi CS (2010)	2
RASSF1	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK1	1	RAF1	3	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Lin YL (2000), Dougherty MK (2005), Zhu J (2005), Blaukat A (2000), Wang J (2009), Wang J (2009), Wang J (2009)	7
FBXO7	1	MAP2K6	2	enzymatic study	Teixeira FR (2016)	1
TRAF6	0	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nishitoh H (1998), Hoeflich KP (1999), Mochida Y (2000), Fujino G (2007), Fujino G (2007)	5
MAP2K6	2	RACK1	2	affinity chromatography technology	Lin J (2015)	1
FBXO7	1	RACK1	2	affinity chromatography technology	Teixeira FR (2016)	1
HGF	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	MAP3K5	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	McLaughlin NJ (2006), McLaughlin NJ (2006), Yoon KW (2009), Yoon KW (2009), Ivanov AA (2017)	5
FGFR4	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DUSP4	1	MAP2K6	2	affinity chromatography technology	Li X (2016)	1
LRRK2	5	MAP2K3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Hsu CH (2010), Hsu CH (2010), Gloeckner CJ (2009), Hsu CH (2010)	4
MAP2K6	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HRAS	2	BRAF	12	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Stang S (1997), Reuter CW (1995), Huttlin EL (2017), Eisenhardt AE (2016), Ivanov AA (2017)	5
MAP3K5	1	MAP2K6	2	pull down, enzymatic study, two hybrid, enzymatic study, enzymatic study	Huang S (2003), Morita K (2001), Takekawa M (2005), Mo JS (2010), Hwang SG (2014)	5
CDKN2B	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	CST1	0	affinity chromatography technology	Huttlin EL (2017)	1
GLIS2	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	MAPKAPK2	1	enzymatic study	ter Haar E (2007)	1
STK11	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RELA	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K4	1	MAP2K3	1	enzymatic study, pull down, pull down, imaging technique	Chan-Hui PY (1998), Takekawa M (2005), Takekawa M (2005), Chen TC (2014)	4
RASSF1	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TLR3	2	MAP2K6	2	enzymatic study	Jiang Z (2003)	1
BECN1	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HRAS	2	RAF1	3	two hybrid, two hybrid, pull down, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Stang S (1997), Germani A (2003), Mitin NY (2004), Vargiu P (2004), Yuryev A (2003), Li W (2000), Li W (2000), Kiyono M (2000), Janoueix-Lerosey I (1998), Boettner B (2000), Karbowniczek M (2006), Han L (1995), Jelinek T (1994), Romero F (1999), Morcos P (1996), Hu CD (1995), Hu CD (1995), Rodriguez-Viciana P (1997), Huang YZ (2003), Stang S (1997), Dougherty MK (2005), Ji H (2016), Fridman M (2000), Ivanov AA (2017)	24
MAP3K5	1	RAF1	3	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Chen J (2001), Chen J (2001), Ivanov AA (2017)	3
MAP2K3	1	MAP2K6	2	genetic interference, affinity chromatography technology, imaging technique, affinity chromatography technology, fluorescent resonance energy transfe	Huber TB (2001), Huttlin EL (2015), Chen TC (2014), Huttlin EL (2017), Ivanov AA (2017)	5
MAP2K5	1	HGF	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K4	3	MAP3K5	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Ryoo K (2004), Song JJ (2004), Kim EK (2007), Zhang H (2004)	4
TRAF6	0	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Ishitani T (2003), Takaesu G (2000), Ninomiya-Tsuji J (1999), Takaesu G (2001), Mochida Y (2000), Mochida Y (2000), Walsh MC (2008), Sorrentino A (2008), Frobose H (2006), Ishitani T (2003), Xia ZP (2009), Jiang Z (2003), Jiang Z (2003), Yamazaki K (2009), Yamazaki K (2009), Jiang Z (2002), Jiang Z (2002), Cui W (2012), Jiang Z (2003), Minoda Y (2009), Gao D (2009), Lee HJ (2012), Hirata Y (2006), Hu MM (2014), Fujikawa H (2013), Sun D (2011), Li W (2015), Lin J (2015), Lee Y (2016), Ji YX (2016), Ji YX (2016), Ji YX (2016), Ji YX (2016)	33
AKT1	1	MAPK14	0	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Rane MJ (2001), Rane MJ (2001), Hartman AD (2006), Rane MJ (2001), Rane MJ (2001), Ivanov AA (2017)	6
SMAD7	1	MAP2K3	1	affinity chromatography technology	Edlund S (2003)	1
MAPK12	1	MAP2K6	2	enzymatic study	Takahashi M (2003)	1
MAP2K5	1	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NPHS1	2	MAP2K6	2	genetic interference	Huber TB (2001)	1
MAP3K7	2	RELA	1	imaging technique	Chen TC (2014)	1
RAF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	MAP2K4	3	enzymatic study	Takekawa M (2005)	1
GLIS2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K4	3	MAPK1	1	pull down	Ho DT (2003)	1
BECN1	2	RELA	1	affinity chromatography technology	Verma N (2017)	1
MAP2K6	2	MAP2K6	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K5	1	MAP3K7	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mochida Y (2000), Mochida Y (2000), Mochida Y (2000), Kim SY (2012), Kim SY (2012)	5
MAP3K4	1	MAP2K4	3	enzymatic study, pull down	Chan-Hui PY (1998), Takekawa M (2005)	2
SMAD7	1	MAP3K7	2	affinity chromatography technology	Edlund S (2003)	1
BRAF	12	PTEN	24	genetic interference	Shen JP (2017)	1
MAP2K6	2	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LRRK2	5	MAP2K4	3	enzymatic study	Gloeckner CJ (2009)	1
BRAF	12	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MLH1	6	MAP2K6	2	two hybrid	Brieger A (2010)	1
NPHS1	2	MAP2K3	1	genetic interference	Huber TB (2001)	1
RASSF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPKAPK2	1	BECN1	2	enzymatic study	Wei Y (2015)	1
MAP2K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	RELA	1	imaging technique	Chen TC (2014)	1
MAP2K5	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	MAPK1	1	enzymatic study	Kumar S (1999)	1
TLR3	2	MAP3K7	2	affinity chromatography technology, affinity chromatography technology	Jiang Z (2003), Cusson-Hermance N (2005)	2
AKT1	1	RAF1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Zimmermann S (1999), Zimmermann S (1999), Wang J (2009), Wang J (2009), Ivanov AA (2017)	5
GLIS2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	AKT1	1	affinity chromatography technology, fluorescent resonance energy transfe	Mistafa O (2010), Ivanov AA (2017)	2
MAPK14	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SMAD7	1	AKT1	1	affinity chromatography technology	Song K (2006)	1
BRAF	12	RAF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Weber CK (2001), Weber CK (2001), Kilili GK (2010), Chen C (2008), Chen C (2008), Lito P (2012), Huttlin EL (2017)	7
MAP2K5	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	FBXO31	4	affinity chromatography technology, affinity chromatography technology	Liu J (2014), Liu J (2014)	2
HGF	1	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TAOK2	8	MAP2K6	2	enzymatic study, affinity chromatography technology, imaging technique	Chen Z (2001), Chen Z (2001), Chen TC (2014)	3
CCND2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PKN1	4	MAP2K3	1	affinity chromatography technology	Takahashi M (2003)	1
MAP2K5	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA2	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK14	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	HRAS	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	ZG16B	0	affinity chromatography technology	Huttlin EL (2015)	1
MAPKAPK2	1	MAPK14	0	affinity chromatography technology, protein complementation assay, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Rane MJ (2001), Srivastav RK (2011), Wang J (2011), Varjosalo M (2013), Rane MJ (2001), White A (2007), ter Haar E (2007), Varjosalo M (2013), Gum RJ (1999), Gum RJ (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Smith JA (2000), Huttlin EL (2017)	16
MAPK1	1	MAPKAPK2	1	affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology	Yannoni YM (2004), Srivastav RK (2011), Powell DW (2003), Krump E (1997)	4
TLR3	2	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang M (2011), Jiang Z (2003), Jiang Z (2003), Cusson-Hermance N (2005), Zinngrebe J (2016)	5
MAP2K3	1	MAPK14	0	enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Chen Z (2001), Casar B (2007), Deacon K (1997), Mo JS (2010), Varjosalo M (2013), Huttlin EL (2015), Li L (2014), Huttlin EL (2017), Ivanov AA (2017)	9
MAP3K7	2	MAP2K6	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Ishitani T (2003), Wang C (2001), Ninomiya-Tsuji J (1999), Sakurai H (2000), Wu ZH (2010), Xia ZP (2009), Jiang Z (2003), Singhirunnusorn P (2005), Jiang Z (2002), Hong S (2007), Kojima H (2005), Huangfu WC (2006), Kajino T (2006), Li MG (2003), Wu X (2007), Shambharkar PB (2007), Kishimoto K (2000), Lamb A (2013), Lin J (2015), Liu X (2013), Ninomiya-Tsuji J (2003)	21
GLIS2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTEN	24	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PKN1	4	MAPK12	1	enzymatic study, affinity chromatography technology	Takahashi M (2003), Takahashi M (2003)	2
RASSF1	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EPHA2	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K4	1	GADD45A	1	two hybrid, affinity chromatography technology	Takekawa M (1998), Takekawa M (1998)	2
BRAF	12	RASSF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	HRAS	2	pull down, affinity chromatography technology	Vos MD (2000), Vos MD (2000)	2
TRAF6	0	AKT1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Yang WL (2009), Mitra S (2011), Mitra S (2011)	3
RAF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RELA	1	MAPK14	0	two hybrid	Vinayagam A (2011)	1
GLIS2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PLCB2	0	MAPK14	0	affinity chromatography technology	Barr AJ (2002)	1
MAP2K6	2	MAP2K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SMAD7	1	MAP2K6	2	affinity chromatography technology	Edlund S (2003)	1
MAP2K5	1	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	MAP2K4	3	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Park HS (2002), Park HS (2002), Park HS (2002), Song JJ (2005), Song JJ (2005)	5
MAP2K4	3	MAPK14	0	enzymatic study, affinity chromatography technology, pull down	Deacon K (1997), Xia Y (1998), Xia Y (1998)	3
GADD45A	1	MAPK1	1	affinity chromatography technology	Reinhardt HC (2010)	1
MAP2K6	2	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	BRAF	12	affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique, fluorescent resonance energy transfe	Guan KL (2000), Guan KL (2000), Guan KL (2000), Chen TC (2014), Ivanov AA (2017)	5
BECN1	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	MAPKAPK2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, imaging technique	Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Chen TC (2014)	7
FGFR4	6	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GLIS2	2	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRAF	12	MAP2K6	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K7	2	RACK1	2	affinity chromatography technology	Lin J (2015)	1
MAPK14	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K3	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K5	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BECN1	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TAOK2	8	MAP3K7	2	affinity chromatography technology, affinity chromatography technology	Huangfu WC (2006), Huangfu WC (2006)	2
MAPK14	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NPHS1	2	MAP2K4	3	genetic interference	Huber TB (2001)	1
GLIS2	2	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K5	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAPK1	1	MAPK12	1	affinity chromatography technology	Varjosalo M (2013)	1
MAP3K5	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Kim AH (2001), Kim AH (2001)	2
DUSP4	1	MAPK1	1	affinity chromatography technology, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
EPHA2	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	HGF	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2B	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	GADD45A	1	imaging technique	Chen TC (2014)	1
DUSP4	1	MAPK14	0	pull down, affinity chromatography technology	Chen P (2001), Li X (2016)	2
RELA	1	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	MAP2K3	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP2K6	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HGF	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PLCB2	0	MAP2K6	2	affinity chromatography technology	Barr AJ (2002)	1