Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
CA10	56934	ZONISAMIDE	CHEMBL750	inhibitor	DrugBank	18782051, 17762320, 17582922, 19703035, 18537527

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
CA10	rs967676	CC + CT	fluticasone propionate	efficacy	yes	ONLY in patients with atopic asthma phenotype - results were not significant when considering those with nonatopic asthma (n = 84, p = 0.207) or when considering atopic and nonatopic asthma patients together (n = 288, p = 0.293). Patients with the CC or CT genotype had a higher increase in forced expiratory volume in the first second of expiration (FEV1) as compared to those with the TT genotype. FEV1 was measured before treatment and 4 weeks later. Please note that this SNP was also found to be significantly associated with risk for asthma and severity of asthma. Alleles have been complemented to the plus chromosomal strand.	Genotypes CC + CT is associated with increased response to fluticasone propionate or montelukast in children with Asthma as compared to genotype TT.	24407380	1184169710