PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
BARD1	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Dong Y (2003), Dong Y (2003), Feki A (2005), Jiang J (2011), Tembe V (2015), Tembe V (2015), Tembe V (2015)	7
RAF1	3	RRAS	2	two hybrid, affinity chromatography technology	Yuryev A (2000), Swiercz JM (2009)	2
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
MYC	2	SQSTM1	0	affinity chromatography technology	Koch HB (2007)	1
PPP1CA	3	TP53BP2	5	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Esteves SL (2012), Liu CY (2011), Colland F (2004), Huttlin EL (2015), Hauri S (2013), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	9
BNIP3	2	BNIP3L	1	two hybrid, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Rual JF (2005), Venkatesan K (2009), Rolland T (2014), Huttlin EL (2015), Yu H (2011), Huttlin EL (2017)	6
BCL2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu C (2011), Xu C (2011), Trisciuoglio D (2010)	3
PML	7	PIN1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Reineke EL (2008), Reineke EL (2008), Reineke EL (2010), Reineke EL (2010), Lim JH (2011), El Asmi F (2014)	6
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
TP53	0	BAK1	0	affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Leu JI (2004), Leu JI (2004), Leu JI (2004), Gogada R (2011), Holloway A (2014), Zhang X (2016)	6
BFAR	0	TMBIM6	1	affinity chromatography technology, affinity chromatography technology	Rong J (2011), Rong J (2011)	2
KRAS	1	RAF1	3	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, genetic interference, affinity chromatography technology, fluorescent resonance energy transfe	Li W (2000), Kiyono M (2000), Sui X (2009), Lito P (2012), Rajalingam K (2005), Zhu J (2005), Blaukat A (2000), So J (2015), Ji H (2016), Hart T (2015), Wang T (2017), Saito T (2004), Ivanov AA (2017)	13
BCL2	0	PPP3CA	3	affinity chromatography technology, affinity chromatography technology	Shibasaki F (1997), Rong YP (2009)	2
PPP1CB	9	BCL2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
GIMAP5	0	BCL2	0	affinity chromatography technology, affinity chromatography technology	Nitta T (2006), Nitta T (2006)	2
RAF1	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSPA1A	0	BCL2	0	affinity chromatography technology	Wang Y (1999)	1
CASP8	1	CRYAB	0	affinity chromatography technology	Lee JS (2012)	1
PRKN	1	HNRNPD	3	affinity chromatography technology	Zanon A (2013)	1
BCL2	0	RAD9A	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Komatsu K (2000), Komatsu K (2000), Komatsu K (2000), Komatsu K (2000), Meyerkord CL (2008)	5
CASP8	1	BCL2L1	0	genetic interference	Guo Y (2002)	1
BCAP31	0	BCL2	0	pull down, affinity chromatography technology	Ng FW (1997), Ng FW (1997)	2
CDK1	0	UBE2I	0	enzymatic study, affinity chromatography technology	Tomasi ML (2012), Tomasi ML (2012)	2
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
BCL2	0	HNRNPD	3	two hybrid	Donnini M (2004)	1
BCL2	0	HRK	0	unspecified method, two hybrid, affinity chromatography technology	Chen L (2005), Inohara N (1997), Inohara N (1997)	3
BCL2	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Trisciuoglio D (2010), Trisciuoglio D (2010)	2
IKBKG	0	PPP2CA	7	affinity chromatography technology	Kray AE (2005)	1
BRCA1	7	XIAP	0	affinity chromatography technology, pull down	Martin SA (2005), Martin SA (2005)	2
BLK	4	BCL2L1	0	pull down	Hegde R (1998)	1
BCL2L1	0	PMAIP1	0	unspecified method, affinity chromatography technology, unspecified method	Chen L (2005), Oda E (2000), Kuwana T (2005)	3
TP53	0	BAG1	1	genetic interference	Matsuzawa S (1998)	1
RAF1	3	BCL2	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang HG (1996), Wang HG (1996), Wang HG (1996), Jin S (2005), Jin S (2005), Mazzocca A (2003)	6
MYC	2	BNIP2	0	genetic interference	Toyoshima M (2012)	1
IKBKG	0	PRKN	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Henn IH (2007), Henn IH (2007), Sha D (2010)	3
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
BAD	1	BCL2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down	Chen L (2005), Jin Z (2005), Jin Z (2005), Strobel T (1998), Zhang H (2002), Ayllon V (2002), Komatsu K (2000), Yang E (1995), Yang E (1995), Petros AM (2000), Chattopadhyay A (2001), Iwahashi H (1997), Komatsu K (2000), Wang J (2008), Wang J (2008), Polzien L (2009), Wang J (2011), Kuwana T (2005), Zha J (1997), Zha J (1997), Zha J (1997), Rolland T (2014), Jin L (2009), Certo M (2006), Craik AC (2010), Craik AC (2010), Huttlin EL (2015), Chen TC (2014), Stegh AH (2010), Huttlin EL (2017), Schuermann A (2000)	31
TP53	0	CRYAB	0	affinity chromatography technology, affinity chromatography technology	Jin X (2009), Watanabe G (2009)	2
BLK	4	BCL2	0	pull down	Hegde R (1998)	1
BECN1	2	MDM4	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	BAX	3	imaging technique, affinity chromatography technology, pull down	Chen TC (2014), Kim EM (2014), Kim EM (2014)	3
BCL2	0	CASP8	1	affinity chromatography technology, genetic interference, two hybrid, affinity chromatography technology	Poulaki V (2001), Guo Y (2002), Zhu J (2005), Zhu J (2005)	4
CHUK	5	CASP8	1	affinity chromatography technology	Chaudhary PM (2000)	1
IKBKG	0	HSPA1A	0	pull down	Agou F (2002)	1
HNRNPD	3	UBE2I	0	two hybrid, pull down	Moraes KC (2003), Moraes KC (2003)	2
XIAP	0	BCL2	0	pull down, enzymatic study	Edison N (2017), Edison N (2017)	2
ITPR1	25	BRCA1	7	pull down, affinity chromatography technology, biochemical, fluorescent resonance energy transfe	Hedgepeth SC (2015), Hedgepeth SC (2015), Hedgepeth SC (2015), Hedgepeth SC (2015)	4
BRCA1	7	UBE2I	0	fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, affinity chromatography technology	Morris JR (2009), Morris JR (2009), Xu J (2009), Xu J (2009)	4
MAPK8	3	BCL2L11	4	enzymatic study	Lei K (2003)	1
MAPK1	1	HIF1A	1	enzymatic study	Sang N (2003)	1
BAG3	4	CDK1	0	affinity chromatography technology	Chen Y (2013)	1
BCL2	0	MYC	2	affinity chromatography technology, imaging technique	Jin Z (2004), Jin Z (2004)	2
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
DYNLL1	0	BMF	0	pull down	Day CL (2004)	1
PIN1	0	PPP2CA	7	biochemical	Havugimana PC (2012)	1
BCL2L1	0	BECN1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liang XH (1998), Wang J (2008), Wang J (2008), Tang Y (2012), Noble CG (2008), Noble CG (2008), Pimkina J (2009), Pimkina J (2009), Zalckvar E (2009), Luo S (2010)	10
PPP1CA	3	PPP1CB	9	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	6
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
BCL2L1	0	BIK	0	two hybrid, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method	Rual JF (2005), Chen L (2005), Chen L (2005), Gillissen B (2003), Gillissen B (2003), Jiang A (2001), Kuwana T (2005), Certo M (2006)	8
BCL2	0	ITPR1	25	affinity chromatography technology, affinity chromatography technology, pull down	Oakes SA (2005), Rong YP (2009), Rong YP (2009)	3
GIMAP5	0	BCL2L11	4	affinity chromatography technology	Nitta T (2006)	1
BAD	1	BAX	3	affinity chromatography technology	Flores-Delgado G (2007)	1
PARP1	3	UBE2I	0	two hybrid, affinity chromatography technology, pull down, enzymatic study, enzymatic study, pull down, enzymatic study	Masson M (1997), Masson M (1997), Masson M (1997), Zilio N (2013), Matafora V (2009), Zilio N (2013), Gocke CB (2005)	7
BAX	3	CASP3	0	biochemical	Chandra D (2004)	1
BNIPL	9	BCL2	0	two hybrid, affinity chromatography technology	Qin W (2003), Qin W (2003)	2
PRKN	1	VDAC1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okatsu K (2012), Sun Y (2012), Sun Y (2012), Sarraf SA (2013), Ham SJ (2016), Ham SJ (2016)	6
CDK4	2	MYC	2	enzymatic study, two hybrid, fluorescent resonance energy transfe	Anders L (2011), Wang J (2011), Ivanov AA (2017)	3
NR4A1	4	BCL2	0	pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lin B (2004), Lin B (2004), Lin B (2004), Lin B (2004), Lin B (2004), Han YH (2006), Kolluri SK (2008), Kolluri SK (2008)	8
BFAR	0	BCL2	0	affinity chromatography technology, two hybrid	Zhang H (2000), Zhang H (2000)	2
TMBIM6	1	BCL2	0	affinity chromatography technology	Xu Q (1998)	1
PPARA	1	BCL2	0	enzymatic study, affinity chromatography technology	Gao J (2015), Gao J (2015)	2
BFAR	0	BCL2L1	0	affinity chromatography technology	Zhang H (2000)	1
BCL2L1	0	HRK	0	fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method	Whitfield J (2003), Inohara N (1997), Inohara N (1997), Imaizumi K (1999), Imaizumi K (1999), Kuwana T (2005), Certo M (2006)	7
KRAS	1	UBE2I	0	genetic interference	Luo J (2009)	1
HSP90AA1	7	HIF1A	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hogenesch JB (1997), Qian DZ (2006), Kong X (2006), Kubo T (2004), Zhou J (2004), Fu B (2007), Choi YK (2010), Choi YK (2010), Lee JM (2011), Liu YV (2007), Liu YV (2007), Katschinski DM (2004), Katschinski DM (2004), Katschinski DM (2004), Trisciuoglio D (2010), Trisciuoglio D (2010), Ueda K (2008), Sun H (2013), Kawanami D (2009), Prince TL (2015), Prince TL (2015), Isaacs JS (2004), Lee SH (2015)	23
CASP2	1	BCL2L1	0	genetic interference	Guo Y (2002)	1
IKBKB	1	KEAP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee DF (2009), Lee DF (2009), Lee DF (2009), Lee DF (2009), Lee DF (2009), Kim JE (2010), Kim JE (2010), Niture SK (2013), Hast BE (2014), Hast BE (2014), Edwards MR (2015), Mei ZZ (2016)	12
BCL2	0	PPID	0	affinity chromatography technology, pull down, two hybrid	Eliseev RA (2009), Eliseev RA (2009), Eliseev RA (2009)	3
PPP2CA	7	AMBRA1	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Cianfanelli V (2015), Cianfanelli V (2015), Cianfanelli V (2015)	3
MAPK8	3	BCL2	0	enzymatic study	Kang CB (2005)	1
PIN1	0	TP53	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down	Wulf GM (2002), Wulf GM (2002), Zacchi P (2002), Zacchi P (2002), Vinayagam A (2011), Mantovani F (2007)	6
BAG3	4	PPP2CA	7	affinity chromatography technology	Chen Y (2013)	1
BCAP31	0	CASP8	1	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, biochemical	Ng FW (1997), Ng FW (1997), Ng FW (1997), Iwasawa R (2011), Chandra D (2004), Breckenridge DG (2002), Breckenridge DG (2002)	7
BAG3	4	CRYAB	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Hishiya A (2011), Hishiya A (2011), Hishiya A (2011), Huttlin EL (2015), Huttlin EL (2017)	5
MAPK1	1	KRAS	1	affinity chromatography technology, genetic interference	Blaukat A (2000), Hart T (2015)	2
MAPK1	1	RAF1	3	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Lin YL (2000), Dougherty MK (2005), Zhu J (2005), Blaukat A (2000), Wang J (2009), Wang J (2009), Wang J (2009)	7
BECN1	2	BRCA1	7	affinity chromatography technology	Tang MK (2014)	1
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
PRKN	1	BCL2	0	pull down, affinity chromatography technology	Chen D (2010), Chen D (2010)	2
CHUK	5	PPP1CA	3	affinity chromatography technology, affinity chromatography technology	Mitsuhashi S (2008), Mitsuhashi S (2008)	2
PPP1CB	9	BRCA1	7	affinity chromatography technology, pull down	Winter SL (2007), Winter SL (2007)	2
MOAP1	0	BCL2L1	0	affinity chromatography technology	Tan KO (2001)	1
BAG3	4	VDAC1	2	affinity chromatography technology	Chen Y (2013)	1
CDK1	0	MDM4	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Elias B (2005), Elias B (2005), Elias B (2005)	3
HSPA1A	0	BAG1	1	pull down	Shatkina L (2003)	1
TP53	0	SMN1	0	affinity chromatography technology, pull down, two hybrid	Young PJ (2002), Young PJ (2002), Vinayagam A (2011)	3
TP53AIP1	0	BCL2	0	affinity chromatography technology	Matsuda K (2002)	1
RTN3	2	RTN4	4	two hybrid, affinity chromatography technology	Rual JF (2005), Huttlin EL (2017)	2
HSPA1A	0	BECN1	2	affinity chromatography technology, affinity chromatography technology	Yang Y (2013), Yang Y (2013)	2
CASP8	1	PPP2CA	7	affinity chromatography technology	Xu J (2015)	1
CASP3	0	MAPK8	3	enzymatic study	Enomoto A (2003)	1
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
CASP8	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pan JA (2011), Huang S (2013), Huang S (2013)	3
MAPK8	3	BCL2L1	0	imaging technique, enzymatic study	Chen TC (2014), Wang J (2012)	2
BCL2L1	0	RAD9A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Komatsu K (2000), Komatsu K (2000), Komatsu K (2000)	4
PRKN	1	BECN1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Choubey V (2014), Lonskaya I (2014), Lonskaya I (2014), Lonskaya I (2014)	4
BID	1	BAK1	0	unspecified method	Holloway A (2014)	1
KEAP1	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, two hybrid	Niture SK (2013), Prince TL (2015), Prince TL (2015)	3
BCL2	0	CDK4	2	genetic interference	Shen JP (2017)	1
CASP2	1	BID	1	enzymatic study, enzymatic study	Paroni G (2001), Guo Y (2002)	2
BCL2	0	MAT2A	2	affinity chromatography technology	Tomasi ML (2015)	1
HSP90AA1	7	BLK	4	affinity chromatography technology	Taipale M (2012)	1
BAG3	4	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gamerdinger M (2009), Gamerdinger M (2009), Chen Y (2013)	3
CASP3	0	PARP1	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nicholson DW (1995), Lueschen S (1998), Walsh JG (2008), Boucher D (2012), Luo S (2010), Betin VM (2009)	6
SPNS1	1	BCL2L1	0	affinity chromatography technology	Yanagisawa H (2003)	1
MAPK1	1	BCL2L11	4	affinity chromatography technology, affinity chromatography technology	He C (2014), He C (2014)	2
IKBKB	1	IRS1	7	affinity chromatography technology	Gao Z (2002)	1
TP53	0	CHUK	5	affinity chromatography technology	Huang WC (2007)	1
UBE2I	0	PPARA	1	pull down, enzymatic study	Pourcet B (2010), Pourcet B (2010)	2
PRKN	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Taipale M (2012), Zanon A (2013)	3
BCL2	0	ITLN1	0	genetic interference	Genovese G (2012)	1
MYC	2	PIN1	0	affinity chromatography technology, affinity chromatography technology	Arnold HK (2009), Yeh E (2004)	2
PPP1CA	3	CDK1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
BECN1	2	RAF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PML	7	SQSTM1	0	affinity chromatography technology	Hein MY (2015)	1
CASP8	1	XIAP	0	genetic interference, affinity chromatography technology, affinity chromatography technology	Guo Y (2002), Lee JS (2012), McDonald ER (2004)	3
MYC	2	PPP1CA	3	affinity chromatography technology	Koch HB (2007)	1
BECN1	2	TP53BP2	5	affinity chromatography technology	Behrends C (2010)	1
BID	1	BAX	3	imaging technique	Chen TC (2014)	1
CASP2	1	BCL2	0	genetic interference	Guo Y (2002)	1
TP53	0	TP53BP2	5	two hybrid, pull down, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology	Iwabuchi K (1994), Iwabuchi K (1994), Iwabuchi K (1994), Naumovski L (1996), Naumovski L (1996), Naumovski L (1996), Gillotin S (2011)	7
HIF1A	1	IKBKG	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Nowicka AM (2016), Nowicka AM (2016), Nowicka AM (2016), Nowicka AM (2016)	4
CRYAB	0	BCL2	0	affinity chromatography technology, affinity chromatography technology	Launay N (2010), Launay N (2010)	2
DYNLL1	0	XIAP	0	affinity chromatography technology	Boldt K (2016)	1
PPP1CA	3	MDM4	0	affinity chromatography technology, affinity chromatography technology	Lu Z (2012), Lu Z (2012)	2
BCL2L1	0	TP53BP2	5	two hybrid, unspecified method, x-ray crystallography	Vinayagam A (2011), Katz C (2008), Katz C (2008)	3
MDM4	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	RAF1	3	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Alexandrov I (1997), Koch HB (2007), Ivanov AA (2017)	3
HSP90AA1	7	PPID	0	affinity chromatography technology, biochemical, pull down, affinity chromatography technology, pull down	Schuelke JP (2010), Park MS (2011), Shimamoto S (2010), Shimamoto S (2010), Graumann K (2000)	5
BECN1	2	TP53	0	affinity chromatography technology	Verma N (2017)	1
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
PPP2CA	7	CHUK	5	affinity chromatography technology	Kray AE (2005)	1
CAPN2	1	BID	1	enzymatic study	Gil-Parrado S (2002)	1
IKBKG	0	CHUK	5	pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Agou F (2002), Chen G (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Rothwarf DM (1998), Rothwarf DM (1998), Hasegawa M (2008), Liu J (2009), Li S (2011), Li S (2011), Xia X (2011), Kensche T (2012), May MJ (2002), Wu ZH (2006), Wu ZH (2006), Palkowitsch L (2008), Le Page C (2001), Le Page C (2001), Huang TT (2002), Sebban-Benin H (2007), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), McKenzie FR (2000), Solt LA (2007), Li XH (2001), Rottenberg S (2002), Poyet JL (2000), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Strnad J (2006), Funakoshi-Tago M (2005), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Marinis JM (2012), Mitsuhashi S (2008), Mitsuhashi S (2008), Fujita H (2014), Lee SH (2012), Jackson SS (2014), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), Liu D (2014), Hein MY (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Bal E (2017)	57
BAK1	0	BAX	3	affinity chromatography technology, affinity chromatography technology	Sundararajan R (2001), Gogada R (2011)	2
MYC	2	PPP2R5A	2	affinity chromatography technology	Arnold HK (2009)	1
PPP1CC	2	BCL2L1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
BAG3	4	BMF	0	affinity chromatography technology	Chen Y (2013)	1
BNIPL	9	BNIP2	0	two hybrid	Qin W (2003)	1
MAPK8	3	CASP8	1	biochemical	Gajate C (2005)	1
PSEN1	11	BCL2	0	two hybrid, affinity chromatography technology	Alberici A (1999), Alberici A (1999)	2
UBE2I	0	CHUK	5	enzymatic study	Bernier-Villamor V (2002)	1
BAX	3	CASP8	1	biochemical	Chandra D (2004)	1
PML	7	MAPK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Warren DT (2010), Lim JH (2011), Lim JH (2011)	3
BID	1	CASP8	1	biochemical, enzymatic study	Gajate C (2005), Guo Y (2002)	2
PARP1	3	BLID	0	two hybrid	Arroyo R (2015)	1
ATP2A3	5	BCL2	0	affinity chromatography technology	Kuo TH (1998)	1
GIMAP5	0	BAX	3	affinity chromatography technology	Nitta T (2006)	1
MYC	2	UBE2I	0	genetic interference	Toyoshima M (2012)	1
BAG3	4	BAX	3	affinity chromatography technology	Chen Y (2013)	1
CRYAB	0	BAX	3	pull down, affinity chromatography technology, affinity chromatography technology	Mao YW (2004), Mao YW (2004), Mao YW (2004)	3
SQSTM1	0	BID	1	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Liang X (2013)	2
BAG3	4	BID	1	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
CAPN2	1	UBE2I	0	affinity chromatography technology	Hsieh YL (2013)	1
KEAP1	0	BRCA1	7	affinity chromatography technology	Ma J (2012)	1
BCL2L11	4	ATP2A3	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VDAC1	2	BCL2L11	4	affinity chromatography technology	Sugiyama T (2002)	1
BCL2L1	0	BCL2	0	unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhang H (2002), Lin B (2004), Kolluri SK (2008), Huttlin EL (2015), Huttlin EL (2017)	5
BAD	1	BCL2	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, pull down, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology	Chen L (2005), Yang E (1995), Yang E (1995), Edlich F (2005), Edlich F (2005), Jin S (2005), Zha J (1997), Zha J (1997), Zha J (1997), Certo M (2006), Craik AC (2010), Schuermann A (2000), Schuermann A (2000)	13
SMN1	0	IKBKG	0	affinity chromatography technology	Kim EK (2017)	1
CDK1	0	BARD1	4	enzymatic study	Hayami R (2005)	1
BCL2L1	0	BMF	0	affinity chromatography technology, unspecified method, two hybrid, unspecified method	Ohgushi M (2005), Kuwana T (2005), Rolland T (2014), Certo M (2006)	4
BBC3	1	BCL2L1	0	affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology	Chen L (2005), Kuwana T (2005), Chipuk JE (2008), Certo M (2006), Tong J (2017)	5
SMN1	0	BCL2	0	two hybrid, affinity chromatography technology, pull down	Iwahashi H (1997), Iwahashi H (1997), Iwahashi H (1997)	3
PPP1CC	2	RAF1	3	affinity chromatography technology, affinity chromatography technology	Mitsuhashi S (2003), Mitsuhashi S (2003)	2
AMBRA1	7	PRKN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Van Humbeeck C (2011), Van Humbeeck C (2011), Van Humbeeck C (2011), Choubey V (2014)	4
SEPT4	2	BCL2	0	affinity chromatography technology, protein complementation assay, unspecified method, protein complementation assay	Edison N (2017), Edison N (2017), Edison N (2017), Edison N (2017)	4
BCL2L1	0	DYNLL1	0	affinity chromatography technology	Puthalakath H (1999)	1
BAD	1	PPP1CA	3	affinity chromatography technology	Flores-Delgado G (2007)	1
PPP2CA	7	PPP2R5A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goudreault M (2009), Goudreault M (2009), McCright B (1996), McCright B (1996), Widau RC (2010), Wan C (2015), Hein MY (2015), Craney A (2016), St-Denis N (2016), Yadav L (2017)	10
BCL2	0	DYNLL1	0	affinity chromatography technology	Puthalakath H (1999)	1
PPP2CA	7	TP53	0	affinity chromatography technology	Shouse GP (2011)	1
BCL2	0	PPP2R5A	2	affinity chromatography technology	Ruvolo PP (2002)	1
ITLN1	0	RRAS	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PML	7	BCL2	0	affinity chromatography technology	Hoetelmans RW (2004)	1
PPP1CC	2	IKBKG	0	affinity chromatography technology	Opaluch AM (2014)	1
SQSTM1	0	HIF1A	1	affinity chromatography technology	Liu XW (2013)	1
PRKN	1	BNIP3	2	imaging technique	Zhang T (2016)	1
PARP1	3	BCL2	0	pull down	Song D (2002)	1
MYC	2	IRS2	6	genetic interference	Toyoshima M (2012)	1
PPP1CC	2	TP53BP2	5	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Esteves SL (2012), Fardilha M (2011), Wang J (2011), Rolland T (2014), Huttlin EL (2015), Hauri S (2013), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	10
MYC	2	HSPA1A	0	affinity chromatography technology	Agrawal P (2010)	1
BCL2	0	IRS2	6	affinity chromatography technology	Ueno H (2000)	1
BAK1	0	BCL2L1	0	two hybrid, affinity chromatography technology, unspecified method, fluorescent resonance energy transfe, affinity chromatography technology, unspecified method, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rual JF (2005), Zhang H (2002), Whitfield J (2003), Willis SN (2005), Willis SN (2005), Degterev A (2001), Venkatesan K (2009), Griffiths GJ (1999), Griffiths GJ (1999), Rudner J (2011), Rudner J (2011)	12
BCL2	0	BIK	0	unspecified method, affinity chromatography technology, two hybrid, unspecified method	Chen L (2005), Gillissen B (2003), Li Y (1998), Certo M (2006)	4
PMAIP1	0	BAX	3	affinity chromatography technology	Sun Y (2005)	1
MOAP1	0	BCL2	0	affinity chromatography technology	Tan KO (2001)	1
IKBKB	1	HIF1A	1	affinity chromatography technology	Nowicka AM (2016)	1
BCL2	0	PPP3CC	0	pull down	Weiwad M (2005)	1
PSEN1	11	BCL2L1	0	two hybrid	Passer BJ (1999)	1
BCL2L1	0	VDAC1	2	pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Weng C (2005), Shi Y (2003), Shimizu S (2000), Shimizu S (2000), Shimizu S (1999), Shimizu S (1999), Ramanathan A (2009)	7
HSP90AA1	7	MDM4	0	affinity chromatography technology	Taipale M (2012)	1
CDK1	0	XIAP	0	enzymatic study	Hou Y (2017)	1
SMN1	0	CHUK	5	affinity chromatography technology	Kim EK (2017)	1
BCL2	0	BNIP3	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boyd JM (1994), Ray R (2000), Wang Y (2013), Wang Y (2013)	4
HNRNPD	3	BRCA1	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Shimizu Y (2012), Lehner B (2004), Ertych N (2016)	3
KRAS	1	TOMM20	0	genetic interference	Luo J (2009)	1
CASP8	1	MAPK1	1	affinity chromatography technology	Yao Z (2007)	1
RAF1	3	BAG1	1	pull down, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Wang HG (1996), Wang HG (1996), Wang HG (1996), Wang HG (1996), Song J (2001), Song J (2001)	6
BAG3	4	PARP1	3	affinity chromatography technology	Chen Y (2013)	1
BCL2L11	4	BCL2	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2005), OConnor L (1998), OConnor L (1998), Hsu SY (1998), Chen S (2009), Chen S (2009), Certo M (2006), Taylor JM (2006), Taylor JM (2006), Konopleva M (2006), Huttlin EL (2015), Rudner J (2011), Rudner J (2011), Huttlin EL (2017)	14
BECN1	2	AMBRA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Strappazzon F (2011), Xia P (2013), Xia P (2013), Xia P (2013), Luciani A (2010), Luciani A (2010), Di Bartolomeo S (2010), Gu W (2014), Gu W (2014), Antonioli M (2014)	11
UBE2I	0	MAT2A	2	enzymatic study	Tomasi ML (2015)	1
PARP1	3	HSPA1A	0	affinity chromatography technology	Choi JR (2016)	1
BCL2	0	SERPINB8	1	affinity chromatography technology	Hoetelmans RW (2004)	1
BCL2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Pathan N (2002), Pathan N (2001), Ling YH (1998)	3
TP53	0	BCL2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo KS (2011), Jung JH (2011), Jung JH (2011), Mancini F (2009), Mancini F (2009)	5
BCL2L1	0	TP53	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Vinayagam A (2011), Tang WH (2014), Saxena R (2016), Stegh AH (2010), Kim EM (2014)	5
BCL2L10	0	BCL2	0	affinity chromatography technology	Ke N (2001)	1
PML	7	TOMM20	0	affinity chromatography technology	Hein MY (2015)	1
MAPK1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique	Persons DL (2000), How PC (2011), Srivastav RK (2011), Fogeron ML (2013), Chen TC (2014)	5
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
PPP2CA	7	BCL2	0	enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Deng X (1998), Deng X (1998), Deng X (1998), Tamura Y (2004), Tamura Y (2004)	5
AVEN	3	BCL2	0	two hybrid, affinity chromatography technology	Chau BN (2000), Chau BN (2000)	2
UBE2I	0	HIF1A	1	enzymatic study, enzymatic study	Matic I (2008), Bae SH (2004)	2
MYC	2	AMBRA1	7	affinity chromatography technology	Cianfanelli V (2015)	1
MYC	2	MAPK1	1	pull down, pull down	Jin Z (2004), Gupta S (1994)	2
MAPK8	3	IRS1	7	two hybrid, affinity chromatography technology, pull down	Aguirre V (2002), Aguirre V (2000), Aguirre V (2000)	3
CASP3	0	BID	1	enzymatic study, enzymatic study	Paroni G (2001), Walsh JG (2008)	2
MAPK1	1	CAPN2	1	enzymatic study	Glading A (2004)	1
BCL2	0	BNIP3L	1	affinity chromatography technology, pull down	Imazu T (1999), Yasuda M (1999)	2
CDK1	0	SQSTM1	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Linares JF (2011), Linares JF (2011), Linares JF (2011), Galindo-Moreno M (2017)	4
HSP90AA1	7	CHUK	5	affinity chromatography technology, affinity chromatography technology	Qu X (2012), Gano JJ (2010)	2
MAPK8	3	BMF	0	enzymatic study	Lei K (2003)	1
BMF	0	BCL2	0	affinity chromatography technology, affinity chromatography technology, unspecified method	Puthalakath H (2001), Puthalakath H (2001), Certo M (2006)	3
BCL2L1	0	FKBP8	1	affinity chromatography technology	Shirane M (2003)	1
BCL2	0	CHUK	5	affinity chromatography technology	Bodur C (2012)	1
IKBKB	1	PPP1CA	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li HY (2008), Mitsuhashi S (2008), Mitsuhashi S (2008)	3
CASP3	0	CASP2	1	enzymatic study, enzymatic study	Paroni G (2001), Walsh JG (2008)	2
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
BNIP1	1	BCL2	0	pull down	Zhang H (1999)	1
BCL2	0	BAK1	0	affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Lin B (2004), Enyedy IJ (2001), Rudner J (2011), Rudner J (2011)	4
ATG12	1	BCL2	0	affinity chromatography technology	Rubinstein AD (2011)	1
BNIPL	9	BCL2L1	0	two hybrid	Qin W (2003)	1
FKBP8	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Edlich F (2007), Edlich F (2007), Okamoto T (2006), Okamoto T (2006), Okamoto T (2006), Skarra DV (2011)	6
BCL2L10	0	NR4A1	4	affinity chromatography technology	Kolluri SK (2008)	1
PPP1CB	9	MDM4	0	affinity chromatography technology	Lu Z (2012)	1
GIMAP5	0	BCL2L1	0	affinity chromatography technology, affinity chromatography technology	Nitta T (2006), Nitta T (2006)	2
UBE2I	0	CASP2	1	two hybrid	Shirakura H (2005)	1
BCL2	0	BID	1	unspecified method, unspecified method, pull down, affinity chromatography technology, biochemical, unspecified method	Chen L (2005), Real PJ (2004), Kolluri SK (2008), Chipuk JE (2008), Chipuk JE (2008), Certo M (2006)	6
BNIPL	9	FKBP8	1	two hybrid	Wang J (2011)	1
BRCA1	7	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yan Y (2008), Yan Y (2008)	2
PARP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, genetic interference, affinity chromatography technology	Hu Y (2014), Hu Y (2014), Hu Y (2014), Shen JP (2017), Srivas R (2016), Ertych N (2016)	6
CASP8	1	BLID	0	two hybrid	Arroyo R (2015)	1
IKBKB	1	CASP8	1	affinity chromatography technology	Chaudhary PM (2000)	1
PPP1CA	3	BRCA1	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Winter SL (2007), Liu Y (2002), Liu Y (2002), Liu Y (2002), Liu Y (2002), Woods NT (2012), Chen BY (2014)	7
PPP1CC	2	NMT2	2	two hybrid	Fardilha M (2011)	1
KEAP1	0	SQSTM1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Jain A (2010), Jain A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Inami Y (2011), Fan W (2010), Copple IM (2010), Copple IM (2010), Wright T (2013), Tanji K (2013), Ichimura Y (2013), Ichimura Y (2013), Ichimura Y (2013), Hast BE (2014), Hast BE (2014), Lerner C (2013), Rolland T (2014), Gjyshi O (2015), Bakkar N (2015), Milan E (2015), Park S (2016), Ge W (2017), Mildenberger J (2017), Lu K (2017), Lee Y (2017)	30
PPP1CC	2	TP53	0	affinity chromatography technology	Flores-Delgado G (2007)	1
BRCA1	7	CDK4	2	pull down, enzymatic study, enzymatic study	Wang H (1997), Kehn K (2007), Miralem T (2003)	3
BCL2	0	RRAS	2	two hybrid, affinity chromatography technology	Fernandez-Sarabia MJ (1993), Fernandez-Sarabia MJ (1993)	2
TOMM20	0	VDAC1	2	pull down	Schleiff E (1997)	1
MOAP1	0	BAX	3	affinity chromatography technology	Tan KO (2001)	1
HSP90AA1	7	BECN1	2	affinity chromatography technology	Xu C (2011)	1
PPP1CA	3	BCL2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
NR4A1	4	TP53	0	affinity chromatography technology, pull down, pull down	Zhao BX (2006), Zhao BX (2006), Zhao BX (2006)	3
BAG3	4	IKBKG	0	affinity chromatography technology	Ammirante M (2010)	1
HIF1A	1	NR4A1	4	affinity chromatography technology, affinity chromatography technology	Kim BY (2008), Kim BY (2008)	2
PPP1CC	2	MDM4	0	affinity chromatography technology	Lu Z (2012)	1
CDK1	0	BCL2L1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Wang J (2012), Wang J (2012), Wang J (2012)	3
MDM4	0	TP53	0	enzymatic study, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, protein complementation assay, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfe, pull down	Badciong JC (2002), Shvarts A (1997), Shvarts A (1997), Tang Y (2008), Okamoto K (2005), Chen L (2005), Wang X (2001), Ohtsubo C (2009), Zdzalik M (2010), Singh RK (2007), Kim S (2010), Li M (2011), Li M (2011), David Y (2011), de Graaf P (2003), Wade M (2012), Wade M (2012), Wade M (2012), Stad R (2000), Stad R (2000), Bernal F (2010), Bernal F (2010), Bernal F (2010), Bernal F (2010), Miller KR (2010), Zuckerman V (2009), Kallen J (2009), Czarna A (2009), Czarna A (2009), Popowicz GM (2008), Hu B (2007), Sharp DA (1999), Li C (2002), Di Conza G (2012), Mancini F (2009), Mancini F (2009), Wu S (2012), Shan B (2012), Wu S (2012), Wu S (2012), Ranaweera RS (2013), Bista M (2013), Bista M (2013), Wang CL (2014), Wang CL (2014), Rallapalli R (1999), Chang YS (2013), Chang YS (2013), Tan BX (2014), Huttlin EL (2015), Sanchez MC (2010), Sanchez MC (2010), Li YC (2014), Li X (2015), Chen X (2015), Chen L (2015), Chen L (2015), Chen L (2015), Wei X (2016), Wei X (2016), Xie X (2016), Huttlin EL (2017), Borcherds W (2017), Shangary S (2008), Ivanov AA (2017), Mancini F (2016)	66
IRS1	7	IRS2	6	biochemical	Sun H (2003)	1
BNIP1	1	SQSTM1	0	affinity chromatography technology	Tang F (2011)	1
BCL2	0	PIN1	0	affinity chromatography technology	Pathan N (2001)	1
MAPK1	1	VDAC1	2	imaging technique	Galli S (2009)	1
BCAP31	0	BCL2L1	0	pull down, affinity chromatography technology, affinity chromatography technology	Ng FW (1997), Ng FW (1997), Mund T (2003)	3
PPP1CC	2	CDK1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
HIF1A	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAF1	3	XIAP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, enzymatic study, imaging technique	Dogan T (2008), Tian S (2006), Tian S (2006), Tian S (2006), Tian S (2006), Tian S (2006), Chen TC (2014)	7
BAG3	4	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
TP53	0	SQSTM1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Lello P (2006), Horikawa I (2014), Kang JH (2016), Kang JH (2016)	4
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
CASP8	1	BCL2L10	0	two hybrid	Arroyo R (2015)	1
BCL2L1	0	BNIP3L	1	pull down	Yasuda M (1999)	1
SMN1	0	NMT2	2	two hybrid	Vinayagam A (2011)	1
PRKN	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, imaging technique	Sarraf SA (2013), Song P (2016), Song P (2016), Song P (2016), Song P (2016), Hou XO (2015), Geisler S (2014)	7
MAPK8	3	HSP90AA1	7	affinity chromatography technology	Nieto-Miguel T (2008)	1
BNIP1	1	BCL2L1	0	pull down	Zhang H (1999)	1
BBC3	1	BCL2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Chen L (2005), Nakano K (2001), Nakano K (2001), Certo M (2006)	4
XIAP	0	UBE2I	0	two hybrid, two hybrid	Dynek JN (2010), Dynek JN (2010)	2
IKBKG	0	MYC	2	affinity chromatography technology	Kim BY (2010)	1
BCL2L11	4	BCL2L1	0	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2005), Whitfield J (2003), OConnor L (1998), Hsu SY (1998), Ohgushi M (2005), Kuwana T (2005), Wang X (2009), Wang X (2009), Certo M (2006), Huttlin EL (2015), Weber A (2016), Rudner J (2011), Rudner J (2011), Huttlin EL (2017)	14
BCL2	0	SQSTM1	0	affinity chromatography technology, pull down	Zhou L (2013), Zhou L (2014)	2
BARD1	4	MAPK1	1	affinity chromatography technology	Woods NT (2012)	1
GIMAP5	0	BAK1	0	affinity chromatography technology	Nitta T (2006)	1
PRKN	1	CRYAB	0	affinity chromatography technology	Gong Y (2014)	1
BCL2L10	0	BAX	3	affinity chromatography technology	Ke N (2001)	1
CRYAB	0	CASP3	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Stegh AH (2008), Stegh AH (2008), Stegh AH (2008), Lee JS (2012), Jeong WJ (2012)	5
PPP1CC	2	BCL2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
KEAP1	0	BCL2	0	affinity chromatography technology	Niture SK (2013)	1
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
KRAS	1	PIN1	0	genetic interference	Luo J (2009)	1
TP53	0	PPP3CA	3	affinity chromatography technology	Fogeron ML (2013)	1
SMN1	0	IKBKB	1	affinity chromatography technology	Kim EK (2017)	1
CASP8	1	CASP3	0	enzymatic study, enzymatic study, enzymatic study	Guo Y (2002), Srinivasula SM (1996), Chandra D (2004)	3
HSPA1A	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994)	5
BCL2	0	IKBKB	1	affinity chromatography technology	Bodur C (2012)	1
SOD1	0	CRYAB	0	pull down	Yerbury JJ (2013)	1
BCL2	0	BAX	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hoetelmans RW (2004), Lin B (2004), Lin B (2004), Oltvai ZN (1993), Komatsu K (2000), Geng F (2011), Bodur C (2012), Trisciuoglio D (2013), Zhang H (2000), Diaz JL (1997), Dlugosz PJ (2006), Konopleva M (2006), Konopleva M (2006), Czabotar PE (2011)	14
RAF1	3	VDAC1	2	affinity chromatography technology	Le Mellay V (2002)	1
CDK1	0	PML	7	enzymatic study	Yuan WC (2011)	1
MAPK8	3	NR4A1	4	enzymatic study, enzymatic study	Liu B (2007), Kolluri SK (2003)	2
BCL2	0	IRS1	7	affinity chromatography technology, affinity chromatography technology	Ueno H (2000), Ueno H (2000)	2
BAD	1	KEAP1	0	two hybrid	Wang J (2011)	1
IRS1	7	BCL2L1	0	affinity chromatography technology	Ueno H (2000)	1
BECN1	2	DYNLL1	0	affinity chromatography technology	Di Bartolomeo S (2010)	1
BAX	3	XIAP	0	affinity chromatography technology	Gogada R (2011)	1
PPP1CC	2	PPP1CA	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017)	8
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
PRKN	1	HSPA1A	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Imai Y (2002), Imai Y (2002), Imai Y (2002), Zanon A (2013)	4
IKBKB	1	HSP90AA1	7	affinity chromatography technology	Xue J (2010)	1
CASP8	1	CASP2	1	enzymatic study, enzymatic study	Guo Y (2002), Srinivasula SM (1996)	2
MYC	2	PML	7	affinity chromatography technology, affinity chromatography technology, pull down	Cairo S (2005), Buschbeck M (2007), Buschbeck M (2007)	3
IKBKB	1	TP53	0	enzymatic study	Xia Y (2009)	1
SQSTM1	0	MAPK1	1	affinity chromatography technology	Linares JF (2011)	1
MAPK8	3	MYC	2	enzymatic study, pull down, affinity chromatography technology	Noguchi K (1999), Noguchi K (1999), Noguchi K (1999)	3
NMT2	2	BCL2	0	affinity chromatography technology	Selvakumar P (2006)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
BCL2	0	SOD1	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Pasinelli P (2004), Pasinelli P (2004), Pasinelli P (2004), Pasinelli P (2004)	4
MYC	2	HIF1A	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Koshiji M (2004), Koshiji M (2004), Ivanov AA (2017)	3
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
BCL2L1	0	BLID	0	pull down, affinity chromatography technology, affinity chromatography technology	Broustas CG (2010), Broustas CG (2010), Broustas CG (2010)	3
TP53BP2	5	BCL2	0	two hybrid, pull down, pull down, unspecified method	Naumovski L (1996), Naumovski L (1996), Katz C (2008), Katz C (2008)	4
BCL2	0	FKBP8	1	affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology	Shirane M (2003), Edlich F (2007), Kang CB (2005), Kang CB (2005), Edlich F (2005), Edlich F (2005), Edlich F (2005), Edlich F (2007), Edlich F (2007)	9
BRCA1	7	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Kang HJ (2006), Kang HJ (2006)	2
BAG3	4	BCL2L11	4	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
RAF1	3	BCL2L1	0	pull down, imaging technique	Wang HG (1996), Chen TC (2014)	2
NR4A1	4	RTN4	4	two hybrid	Vinayagam A (2011)	1
CISD2	0	BCL2	0	affinity chromatography technology	Chang NC (2010)	1
BARD1	4	BCL2	0	imaging technique	Tembe V (2015)	1
PIN1	0	RAF1	3	affinity chromatography technology, affinity chromatography technology	Dougherty MK (2005), Dougherty MK (2005)	2
SOD1	0	MAT2A	2	affinity chromatography technology	Malty RH (2017)	1
BFAR	0	CASP8	1	affinity chromatography technology	Zhang H (2000)	1
BID	1	MAPK8	3	biochemical	Gajate C (2005)	1
IKBKG	0	BCL2	0	affinity chromatography technology	Shambharkar PB (2007)	1
BECN1	2	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BCL2	0	KRAS	1	affinity chromatography technology, affinity chromatography technology	Wang X (2009), Wang X (2009)	2
MAPK8	3	RAF1	3	two hybrid	Wang J (2011)	1
SPNS1	1	BCL2	0	affinity chromatography technology	Yanagisawa H (2003)	1
TOMM20	0	BCL2	0	pull down	Schleiff E (1997)	1
MYC	2	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Arnold HK (2009), Junttila MR (2007), Cianfanelli V (2015), Cianfanelli V (2015)	4
BCL2L1	0	BNIP3	2	two hybrid, two hybrid, affinity chromatography technology	Ray R (2000), Ray R (2000), Ray R (2000)	3
PPP1CB	9	TP53BP2	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Rolland T (2014), Hauri S (2013), St-Denis N (2016), Yadav L (2017), Yadav L (2017)	5
XIAP	0	CRYAB	0	affinity chromatography technology	Lee JS (2012)	1
PML	7	NR4A1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Wu WS (2002), Wu WS (2002), Wu WS (2002), Wu WS (2002)	4
MAPK8	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Hu MC (1997), Yin ZM (2004), Yin ZM (2004), Fuchs SY (1998), Topisirovic I (2009), Drago-Ferrante R (2008), Wang J (2000), Chang NS (2003), Fuchs SY (1998)	9
PARP1	3	HIF1A	1	affinity chromatography technology	Elser M (2008)	1
HNRNPD	3	MYC	2	unspecified method	Lu M (2013)	1
XIAP	0	CASP3	0	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down	Suzuki Y (2001), Suzuki Y (2001), Silke J (2002), Riedl SJ (2001), Riedl SJ (2001), Roy N (1997), Deveraux QL (1997), Deveraux QL (1997), Suzuki Y (2001), Bartke T (2004), Nakhaei P (2012), Qiu XB (2005), Nomura T (2003), Paulsen M (2008), Scott FL (2005), Mufti AR (2006), Rajalingam K (2006), Dudich E (2006), Chai J (2001), Checinska A (2007), Sun M (2009), Takahashi R (1998), Conde C (2012), Walsh JG (2008), Lee JS (2012), Lin YF (2013), Huttlin EL (2015), Chen TC (2014), Huttlin EL (2017), Hou Y (2017)	30
BAG1	1	BAG3	4	biochemical	Havugimana PC (2012)	1
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RTN4	4	BCL2	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tagami S (2000), Tagami S (2000), Tagami S (2000), Wan Q (2007)	4
RAF1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016)	15
MAPK1	1	PPP1CC	2	affinity chromatography technology	Quevedo C (2003)	1
HSP90AA1	7	HSPA1A	0	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kanelakis KC (2002), Gano JJ (2010), Falsone SF (2005), Brychzy A (2003), Scholz GM (2001), Scholz GM (2001)	6
BCL2	0	BECN1	2	two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liang XH (1998), Liang XH (1998), Chen D (2010), Xu C (2011), Chang NC (2010), Strappazzon F (2011), Zhou L (2013), Molejon MI (2013), Yang L (2012), Yang L (2012), Trisciuoglio D (2013), Han J (2012), Wang Y (2013), Wang Y (2013), Luciani A (2010), Luciani A (2010), Ciechomska IA (2009), Noble CG (2008), Noble CG (2008), Sun Q (2008), Rovito D (2013), Pattingre S (2005), Pattingre S (2005), Criollo A (2010), Tang D (2010), Tang D (2010), Chauhan S (2015), Rui YN (2015), Rui YN (2015), Verma N (2017), Yuan G (2014), Li X (2017)	32
BCL2L1	0	AVEN	3	two hybrid, two hybrid, affinity chromatography technology	Chau BN (2000), Chau BN (2000), Chau BN (2000)	3
VDAC1	2	CDK1	0	affinity chromatography technology	Malty RH (2017)	1
NMT2	2	TP53	0	affinity chromatography technology	Selvakumar P (2006)	1
BAG3	4	CASP3	0	biochemical	Wan C (2015)	1
RAF1	3	BAD	1	enzymatic study, enzymatic study, imaging technique	Jin S (2005), Polzien L (2009), Chen TC (2014)	3
BNIP2	0	BCL2	0	two hybrid, two hybrid, pull down	Qin W (2003), Boyd JM (1994), Boyd JM (1994)	3
PPP1CA	3	TP53	0	two hybrid	Colland F (2004)	1
BAX	3	VDAC1	2	pull down, pull down	Weng C (2005), Shi Y (2003)	2
PIN1	0	SOD1	0	biochemical	Wan C (2015)	1
PRKN	1	MAPK1	1	affinity chromatography technology	Um JW (2012)	1
BCL2	0	UBE2I	0	affinity chromatography technology	Tomasi ML (2015)	1
IKBKG	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Martin P (2006), Zotti T (2014)	2
KRAS	1	PSEN1	11	genetic interference	Luo J (2009)	1
BCAP31	0	BFAR	0	affinity chromatography technology	Roth W (2003)	1
DYNLL1	0	RAF1	3	affinity chromatography technology	Boldt K (2016)	1
PPP2CA	7	IKBKB	1	affinity chromatography technology	Kray AE (2005)	1
BCL2L1	0	BID	1	unspecified method, unspecified method, unspecified method, imaging technique	Chen L (2005), Kuwana T (2005), Certo M (2006), Chen TC (2014)	4
UBE2I	0	TP53	0	two hybrid, two hybrid, two hybrid, enzymatic study, two hybrid, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Minty A (2000), Gallagher WM (1999), Shen Z (1996), Bernier-Villamor V (2002), Wang J (2008), Spektor TM (2011), Jakobs A (2007), Mohideen F (2009), Lin JY (2004), Bennett RL (2012), Heo KS (2013), Morimoto M (2003), Rodriguez MS (1999), Muller S (2000), Fernandez-Lloris R (2006), Mohan RD (2007), Brandt M (2013), Weger S (2005)	18
BCL2	0	MDM4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mancini F (2009), Mancini F (2009), Wang CL (2014)	3
ITM2B	2	BCL2	0	affinity chromatography technology	Fleischer A (2002)	1
BCL2	0	BCL2	0	affinity chromatography technology, pull down	Kolluri SK (2008), Diaz JL (1997)	2
BCL2L11	4	BAX	3	affinity chromatography technology	Huttlin EL (2015)	1
CASP3	0	BCL2	0	enzymatic study	Liang Y (2002)	1
IKBKB	1	CHUK	5	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017)	30
BARD1	4	PARP1	3	affinity chromatography technology	Hu Y (2014)	1
BAG3	4	BCL2	0	affinity chromatography technology	Boiani M (2013)	1
CASP3	0	SERPINB8	1	biochemical	Wan C (2015)	1
RAF1	3	KEAP1	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CASP8	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Yao Z (2007), Yao Z (2007)	2
BAG3	4	HSP90AA1	7	affinity chromatography technology	Chen Y (2013)	1
BCL2	0	AMBRA1	7	affinity chromatography technology, affinity chromatography technology	Strappazzon F (2011), Strappazzon F (2011)	2
PPID	0	HSPA1A	0	biochemical	Park MS (2011)	1
BCL2L1	0	PPP1CA	3	affinity chromatography technology, pull down, affinity chromatography technology	Ayllon V (2002), Ayllon V (2002), Flores-Delgado G (2007)	3
VDAC1	2	CISD2	0	biochemical	Wan C (2015)	1
BRCA1	7	PPP2CA	7	affinity chromatography technology	Woods NT (2012)	1
PPP1CB	9	PPP1CC	2	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
BCL2L1	0	PRKN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hollville E (2014), Hollville E (2014), Gong Y (2017), Gong Y (2017), Gong Y (2017)	5
MAPK1	1	BCL2	0	enzymatic study, affinity chromatography technology	Tamura Y (2004), Tamura Y (2004)	2
AMBRA1	7	DYNLL1	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Di Bartolomeo S (2010), Di Bartolomeo S (2010), Boldt K (2016)	3
BAG3	4	HSPA1A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doong H (2000), Antoku K (2001), Chen Y (2013), Hein MY (2015)	4
BCL2	0	BRCA1	7	fluorescent resonance energy transfe, affinity chromatography technology	Laulier C (2011), Laulier C (2011)	2
IKBKB	1	IKBKG	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, biochemical, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, pull down, affinity chromatography technology	Chen G (2002), Chen G (2002), Chariot A (2002), Wu RC (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Fenner BJ (2010), Fenner BJ (2010), Lee KY (2005), Rothwarf DM (1998), Ea CK (2006), Thurston TL (2009), Orel L (2010), Wu ZH (2010), Napolitano G (2009), Liu J (2009), Skaug B (2011), Li S (2011), Li S (2011), Kensche T (2012), Chiaravalli J (2011), Wu CJ (2006), Wu ZH (2006), Ahmad R (2007), Ahmad R (2007), Palkowitsch L (2008), Palkowitsch L (2008), Lo YC (2008), Mabb AM (2006), Baima ET (2010), Tegethoff S (2003), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), Lee DF (2007), Rottenberg S (2002), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Funakoshi-Tago M (2005), Ivins FJ (2009), Shibata Y (2012), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Wu ZH (2008), Mitsuhashi S (2008), Fujita H (2014), Golden MS (2013), Lee SH (2012), Cote SM (2013), Kim HJ (2014), Jackson SS (2014), Liao W (2008), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), So J (2015), Liu D (2014), Guo B (2014), Guo B (2014), Guo B (2014), Zhou L (2014), Zhou L (2014), Hein MY (2015), Bagneris C (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Rushe M (2008), Hauenstein AV (2017), Bal E (2017)	78
BCL2	0	MEX3D	0	two hybrid	Donnini M (2004)	1
BAG1	1	BCL2	0	pull down	Takayama S (1997)	1
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
PPP2CA	7	SOD1	0	biochemical	Havugimana PC (2012)	1
BCL2	0	PMAIP1	0	unspecified method, affinity chromatography technology	Chen L (2005), Oda E (2000)	2
BCL2L1	0	RTN4	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Tagami S (2000), Tagami S (2000), Tagami S (2000)	3
BCL2	0	RTN3	2	affinity chromatography technology	Wan Q (2007)	1
CASP2	1	CRYAB	0	affinity chromatography technology	Jeong WJ (2012)	1
DYNLL1	0	BCL2L11	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Day CL (2004), Vadlamudi RK (2004), Lei K (2003), Huttlin EL (2015)	4
SEPT4	2	XIAP	0	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay	Garrison JB (2011), Garrison JB (2011), Bornstein B (2011), Bornstein B (2011), Edison N (2012), Gottfried Y (2004), Gottfried Y (2004), Fu RH (2017), Edison N (2017), Edison N (2017), Edison N (2017)	11
PARP1	3	IKBKG	0	affinity chromatography technology, affinity chromatography technology, pull down	Wu Z (2015), Wu Z (2015), Wu Z (2015)	3
GIMAP5	0	BAD	1	affinity chromatography technology	Nitta T (2006)	1
CRYAB	0	BCL2L1	0	pull down, affinity chromatography technology, affinity chromatography technology	Mao YW (2004), Mao YW (2004), Mao YW (2004)	3
BCL2	0	VDAC1	2	affinity chromatography technology	Rong YP (2009)	1
RAF1	3	PPP2CA	7	affinity chromatography technology	Rajalingam K (2005)	1
CAPN2	1	BCL2	0	enzymatic study, pull down	Gil-Parrado S (2002), Gil-Parrado S (2002)	2
BCL2L1	0	BAX	3	affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Strobel T (1998), Zhang H (2002), Gillissen B (2003), Ren H (2011), Ren H (2011), Chinnaiyan AM (1997), Diaz JL (1997), Wang X (2009), Wang X (2009), Czabotar PE (2011), Czabotar PE (2011), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Tong J (2017), Huttlin EL (2017), Kim EM (2014)	17
VDAC1	2	BCAP31	0	biochemical	Wan C (2015)	1
CASP3	0	BECN1	2	enzymatic study	Luo S (2010)	1
CHUK	5	IRS1	7	affinity chromatography technology	Gao Z (2002)	1
CASP2	1	XIAP	0	genetic interference	Guo Y (2002)	1
CASP8	1	PARP1	3	enzymatic study	Betin VM (2009)	1
CHUK	5	MYC	2	affinity chromatography technology, affinity chromatography technology	Yeh PY (2011), Yeh PY (2011)	2
AMBRA1	7	HSP90AA1	7	affinity chromatography technology	Antonioli M (2014)	1
PPARA	1	HSP90AA1	7	affinity chromatography technology, pull down, two hybrid	Sumanasekera WK (2003), Sumanasekera WK (2003), Sumanasekera WK (2003)	3
PPP1CA	3	CDK4	2	affinity chromatography technology, biochemical	Flores-Delgado G (2007), Havugimana PC (2012)	2
BLID	0	BCL2	0	affinity chromatography technology	Broustas CG (2010)	1
KRAS	1	PML	7	affinity chromatography technology	Hein MY (2015)	1