Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CFB 629 4-GUANIDINO-BENZOIC ACID CHEMBL20767 DrugBank 17139284, 17016423

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CFB rs641153 A ranibizumab efficacy no Patients underwent 5 monthly injections. Good response at month 5 was defined as best-corrected visual acuity improvement of >= 8 Early Treatment Diabetic Retinopathy Study (ETDRS) letters from baseline. Bonferroni correction for multiple testing. Allele A is not associated with response to ranibizumab in people with Macular Degeneration as compared to allele G. 23842101 1184510418