PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RBFOX2	5	DMRTB1	1	two hybrid	Rual JF (2005)	1
C1orf94	1	NIF3L1	0	affinity chromatography technology	Huttlin EL (2017)	1
CTBP2	7	DMRTB1	1	two hybrid	Rolland T (2014)	1
SORBS3	5	HNRNPUL1	1	two hybrid	Rolland T (2014)	1
IL16	2	DMRTB1	1	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
PRMT2	3	DMRTB1	1	two hybrid	Rual JF (2005)	1
DMRTB1	1	KLHL15	1	affinity chromatography technology	Huttlin EL (2017)	1
NEDD9	3	DMRTB1	1	two hybrid	Yu H (2011)	1
CTBP2	7	CTBP1	2	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sewalt RG (1999), Wang J (2011), Corominas R (2014), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
SORBS3	5	NCKIPSD	2	two hybrid	Rolland T (2014)	1
SORBS3	5	DMRTB1	1	two hybrid	Rual JF (2005)	1
RBFOX1	1	DMRTB1	1	two hybrid	Lim J (2006)	1
DMRTB1	1	C1orf94	1	two hybrid	Yu H (2011)	1
RBFOX1	1	RBFOX2	5	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
EWSR1	2	HNRNPUL1	1	two hybrid	Wang J (2011)	1
EWSR1	2	DMRTB1	1	two hybrid	Rual JF (2005)	1
RBFOX1	1	C1orf94	1	two hybrid, two hybrid	Corominas R (2014), Rolland T (2014)	2
CTBP1	2	DMRTB1	1	two hybrid	Rolland T (2014)	1
VASP	0	DMRTB1	1	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
RBFOX2	5	C1orf94	1	two hybrid	Rolland T (2014)	1
HNRNPUL1	1	PRMT2	3	two hybrid, affinity chromatography technology, affinity chromatography technology	Kzhyshkowska J (2001), Kzhyshkowska J (2001), Kzhyshkowska J (2001)	3
DMRTB1	1	TRIM11	1	affinity chromatography technology	Huttlin EL (2017)	1
EWSR1	2	PEF1	0	two hybrid	Rolland T (2014)	1
EWSR1	2	IL16	2	bioid	Elzi DJ (2014)	1
NIF3L1	0	DMRTB1	1	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
NCKIPSD	2	DMRTB1	1	two hybrid	Rual JF (2005)	1
EYA2	2	DMRTB1	1	two hybrid	Rual JF (2005)	1
LENG8	2	DMRTB1	1	two hybrid	Venkatesan K (2009)	1
PEF1	0	DMRTB1	1	two hybrid	Yu H (2011)	1
HNRNPUL1	1	DMRTB1	1	two hybrid	Yu H (2011)	1