PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SNX17	0	SELP	3	two hybrid, x-ray crystallography, pull down, unspecified method	Florian V (2001), Ghai R (2013), Ghai R (2013), Ghai R (2013)	4
GP1BA	0	SELP	3	pull down	Romo GM (1999)	1
SELP	3	AP1M1	3	x-ray crystallography	Owen DJ (2001)	1
SELP	3	SNX27	5	pull down	Ghai R (2013)	1
SELPLG	0	SELP	3	affinity chromatography technology	Epperson TK (2000)	1
EZR	8	SELP	3	pull down	Alonso-Lebrero JL (2000)	1
SELP	3	VCAN	9	pull down	Kawashima H (2000)	1
100133941	0	SELP	3	pull down	Aigner S (1997)	1
SERPING1	2	SELP	3	affinity chromatography technology	Cai S (2003)	1