PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
STAT3	0	PIAS3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Wang LH (2001), Okumura F (2010), Yamamoto T (2003), Yamamoto T (2003), Tsuruma R (2008), Liu B (1998), Wang J (2011)	7
SIAH2	0	SNCA	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liani E (2004), Rott R (2008), Rott R (2008), Szargel R (2009), Rott R (2011)	5
AR	3	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Qi J (2013), Tan G (2017)	2
TYK2	1	SIAH2	0	affinity chromatography technology	Mueller S (2014)	1
SIAH2	0	PIAS3	2	pull down	Depaux A (2007)	1
SETD2	20	SIAH2	0	two hybrid	Wang J (2011)	1
PRR20E	0	SIAH2	0	affinity chromatography technology	Huttlin EL (2017)	1
EEF1D	3	SIAH2	0	two hybrid	Wang J (2011)	1
MYD88	1	SIAH2	0	two hybrid	Wang J (2011)	1
HIPK3	5	ZYX	2	two hybrid	Colland F (2004)	1
KAT2B	2	UBE2D3	1	pull down	Jung CR (2010)	1
KAT5	1	AR	3	enzymatic study, two hybrid, two hybrid, pull down, two hybrid, pull down	Gaughan L (2002), Gaughan L (2002), Brady ME (1999), Brady ME (1999), Gaughan L (2001), Gaughan L (2001)	6
SIAH2	0	PSMD4	1	enzymatic study, enzymatic study	Uchiki T (2009), Kim HT (2012)	2
CEBPD	0	HDAC3	5	affinity chromatography technology, pull down	Lai PH (2008), Turgeon N (2008)	2
PEG10	2	SIAH1	2	two hybrid, pull down, two hybrid	Okabe H (2003), Okabe H (2003), Rolland T (2014)	3
SIAH2	0	TNK2	7	affinity chromatography technology	Buchwald M (2012)	1
CHEK2	2	PML	7	enzymatic study, affinity chromatography technology, affinity chromatography technology	Yang S (2002), Yang S (2002), Yang S (2002)	3
DLD	1	EEF1D	3	affinity chromatography technology	Malty RH (2017)	1
SIAH2	0	UBE2L6	0	affinity chromatography technology	Wheeler TC (2002)	1
SIAH2	0	PIAS1	4	two hybrid, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Depaux A (2007), Depaux A (2007), Depaux A (2007), Depaux A (2007), Lee JH (2016)	5
EGLN3	0	HDAC3	5	affinity chromatography technology	Rodriguez J (2016)	1
SIAH1	2	UBE2D1	0	two hybrid, two hybrid, pull down, pull down, pull down	Matsuzawa SI (2001), Markson G (2009), Dimitrova YN (2010), Rott R (2008), Liu QY (2008)	5
UBE2I	0	SKI	3	pull down, affinity chromatography technology	Ding B (2012), Ding B (2012)	2
SIAH2	0	AKAP1	3	affinity chromatography technology	Carlucci A (2008)	1
USP13	2	DLST	3	affinity chromatography technology	Sowa ME (2009)	1
AFF1	1	SIAH2	0	two hybrid, far western blotting, pull down	Bursen A (2004), Bursen A (2004), Bursen A (2004)	3
UBE2D3	1	SIAH1	2	two hybrid, two hybrid, pull down, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Liu M (2012), Mei Y (2007), Kim SY (2009)	5
AR	3	PIAS3	2	two hybrid	Kotaja N (2000)	1
PEG3	2	SIAH2	0	affinity chromatography technology, two hybrid	Relaix F (2000), Relaix F (2000)	2
KAT5	1	HDAC3	5	affinity chromatography technology	Yi J (2014)	1
OPRM1	0	ZYX	2	two hybrid, pull down	Petko J (2013), Petko J (2013)	2
SIAH2	0	PPP1R13B	9	affinity chromatography technology, pull down, affinity chromatography technology	Kim H (2013), Kim H (2013), Kim H (2013)	3
OPRK1	1	SIAH2	0	affinity chromatography technology	Petko J (2013)	1
EGLN1	3	SPRY2	4	affinity chromatography technology	Anderson K (2011)	1
DLD	1	SIAH2	0	affinity chromatography technology	Huttlin EL (2015)	1
CHEK2	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Kass EM (2009), Kass EM (2009)	2
SH3RF1	1	UBE2D1	0	pull down	Lin DH (2009)	1
SIAH2	0	UBE2D2	0	pull down, pull down, pull down	Szargel R (2009), Avraham E (2005), Rott R (2011)	3
AR	3	UBE2I	0	two hybrid, affinity chromatography technology, genetic interference, enzymatic study	Poukka H (1999), Poukka H (1999), Poukka H (1999), Ogawa H (2009)	4
SPRY2	4	SIAH2	0	pull down	Nadeau RJ (2007)	1
SIAH1	2	RBBP8	1	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Germani A (2003), Germani A (2003), Germani A (2003), Liu H (2015)	4
TINF2	1	SIAH2	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Bhanot M (2011), Bhanot M (2011), Bhanot M (2011), Bhanot M (2011)	4
STAT3	0	PML	7	affinity chromatography technology, pull down	Kawasaki A (2003), Kawasaki A (2003)	2
CHEK2	2	LATS2	1	enzymatic study	Okada N (2011)	1
SNCAIP	2	SNCA	0	two hybrid, fluorescent resonance energy transfe, two hybrid, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Neystat M (2002), Kawamata H (2001), Engelender S (1999), Engelender S (1999), Engelender S (1999), Xie YY (2010), Xie YY (2010), Smith WW (2005), Smith WW (2005), Bandopadhyay R (2005), Lee G (2004), Ryo A (2006), Ryo A (2006), Norris KL (2015), Nagano Y (2001)	15
SIAH2	0	PPP1R12A	6	two hybrid, affinity chromatography technology	Twomey E (2010), Twomey E (2010)	2
TYK2	1	UBE2L6	0	affinity chromatography technology	Mueller S (2014)	1
SIAH2	0	AKR1C3	1	affinity chromatography technology, pull down	Fan L (2015), Fan L (2015)	2
AFF1	1	SIAH1	2	two hybrid, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology	Bursen A (2004), Bursen A (2004), Bursen A (2004), Bursen A (2004), Bursen A (2004)	5
VAV1	2	SIAH2	0	two hybrid, pull down, affinity chromatography technology	Germani A (1999), Germani A (1999), Germani A (1999)	3
TRAF2	1	SPRY2	4	two hybrid	Rual JF (2005)	1
SIAH2	0	SIAH2	0	enzymatic study, enzymatic study, affinity chromatography technology	Stebbins JL (2013), Fan L (2015), Depaux A (2006)	3
SIAH2	0	TP53BP2	5	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Kim H (2013), Kim H (2013), Kim H (2013), Kim H (2013)	4
SIAH2	0	USP19	1	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Altun M (2012), Altun M (2012), Velasco K (2013), Velasco K (2013)	4
SIAH1	2	PIAS1	4	two hybrid, pull down, affinity chromatography technology	Depaux A (2007), Depaux A (2007), Lee JH (2016)	3
PIAS2	2	PIAS1	4	imaging technique	Chen TC (2014)	1
LATS2	1	ZYX	2	affinity chromatography technology, affinity chromatography technology	Ma B (2016), Ma B (2016)	2
SIAH2	0	PIAS2	2	two hybrid	Depaux A (2007)	1
AR	3	LATS2	1	two hybrid, affinity chromatography technology	Powzaniuk M (2004), Powzaniuk M (2004)	2
OPRM1	0	SIAH2	0	two hybrid, affinity chromatography technology	Petko J (2013), Petko J (2013)	2
PIAS1	4	PML	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	3
KAT2B	2	UBE2D1	0	pull down	Wang Y (2011)	1
UBE2I	0	PML	7	enzymatic study, pull down, enzymatic study, two hybrid, two hybrid, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down	Knipscheer P (2008), Kim YE (2005), Satow R (2012), Duprez E (1999), Wang J (2011), Tatham MH (2003), Duprez E (1999), Gocke CB (2005), Lin DY (2006), Jo S (2016), Schilling EM (2017)	11
MYD88	1	SIAH1	2	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
DYRK2	1	SIAH2	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method	Perez M (2012), Perez M (2012), Perez M (2012), Perez M (2012), Perez M (2012)	5
UBE2I	0	CEBPD	0	enzymatic study	Wang JM (2006)	1
HIPK3	5	SIAH2	0	two hybrid	Colland F (2004)	1
SIAH2	0	SH3RF1	1	two hybrid, affinity chromatography technology	Christian PA (2011), Christian PA (2011)	2
DYRK2	1	UBE2D1	0	pull down	Jung HY (2013)	1
TRAF2	1	SIAH2	0	pull down	Habelhah H (2002)	1
HIPK3	5	SIAH1	2	two hybrid	Colland F (2004)	1
NFE2L2	1	HDAC3	5	affinity chromatography technology	Lee DY (2012)	1
PEG3	2	SIAH1	2	affinity chromatography technology, two hybrid	Relaix F (2000), Relaix F (2000)	2
DYRK2	1	DLST	3	affinity chromatography technology	Maddika S (2009)	1
PML	7	HDAC3	5	affinity chromatography technology, pull down	Wu WS (2001), Wu WS (2001)	2
SIAH1	2	SH3RF1	1	affinity chromatography technology, affinity chromatography technology	Xu Z (2006), Xu Z (2006)	2
UBE2I	0	PIAS3	2	two hybrid, two hybrid	Bandyopadhyay S (2010), Wang J (2011)	2
SIAH1	2	VAV1	2	two hybrid	Germani A (1999)	1
SNCAIP	2	SIAH1	2	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down	Liani E (2004), Liani E (2004), Liani E (2004), Liani E (2004), Nagano Y (2003), Nagano Y (2003), Nagano Y (2003)	7
TNK2	7	AR	3	affinity chromatography technology, pull down	Mahajan NP (2007), Mahajan NP (2007)	2
EGLN3	0	EGLN2	4	affinity chromatography technology, affinity chromatography technology	Nakayama K (2007), Nakayama K (2007)	2
STAT3	0	KAT5	1	affinity chromatography technology	Xiao H (2003)	1
SIAH1	2	UBE2I	0	two hybrid, two hybrid	Depaux A (2007), Hu G (1997)	2
4985	0	SIAH2	0	affinity chromatography technology	Petko J (2013)	1
CCBE1	2	SIAH2	0	two hybrid	Wang J (2011)	1
MCM2	3	UBE2D2	0	affinity chromatography technology	Drissi R (2015)	1
HIPK2	0	SIAH2	0	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Lee MG (2014)	5
ATN1	2	SIAH2	0	two hybrid	Lim J (2006)	1
PPP1CC	2	TP53BP2	5	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Esteves SL (2012), Fardilha M (2011), Wang J (2011), Rolland T (2014), Huttlin EL (2015), Hauri S (2013), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	10
SKI	3	LATS2	1	affinity chromatography technology	Rashidian J (2015)	1
PML	7	SIAH2	0	affinity chromatography technology, affinity chromatography technology, pull down	Fanelli M (2004), Fanelli M (2004), Fanelli M (2004)	3
SPRY2	4	UBE2D2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PML	7	KAT5	1	affinity chromatography technology, pull down	Wu Q (2009), Wu Q (2009)	2
AR	3	PIAS1	4	two hybrid, affinity chromatography technology	Kotaja N (2000), Toropainen S (2015)	2
EGLN3	0	TPX2	4	affinity chromatography technology	Rodriguez J (2016)	1
OPRK1	1	SIAH1	2	affinity chromatography technology	Petko J (2013)	1
PML	7	SKI	3	affinity chromatography technology, pull down	Khan MM (2001), Khan MM (2001)	2
SIAH2	0	HDAC3	5	affinity chromatography technology	Zhao HL (2010)	1
SIAH2	0	PLCE1	2	affinity chromatography technology, pull down, affinity chromatography technology	Yun S (2008), Yun S (2008), Yun S (2008)	3
OPRM1	0	SIAH1	2	two hybrid, pull down, affinity chromatography technology	Petko J (2013), Petko J (2013), Petko J (2013)	3
TRAF2	1	PEG3	2	affinity chromatography technology, two hybrid	Relaix F (1998), Relaix F (1998)	2
XAF1	1	HIPK2	0	genetic interference, affinity chromatography technology	Lee MG (2014), Lee MG (2014)	2
EGLN3	0	PML	7	affinity chromatography technology	Rodriguez J (2016)	1
STAT3	0	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Tsuruma R (2008), Kato M (2015)	5
EGLN3	0	SIAH2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Nakayama K (2007), Nakayama K (2004), Nakayama K (2004), Gopalsamy A (2014), Gopalsamy A (2014)	5
AR	3	HDAC3	5	pull down, affinity chromatography technology	Franco PJ (2003), Zhu P (2006)	2
PPP1CC	2	SNCAIP	2	affinity chromatography technology, two hybrid, far western blotting, imaging technique, affinity chromatography technology	Huttlin EL (2015), Ferreira-Fernandes E (2015), Ferreira-Fernandes E (2015), Ferreira-Fernandes E (2015), Huttlin EL (2017)	5
PPP1CC	2	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Cid C (2007), Cid C (2007)	2
DCC	3	AR	3	affinity chromatography technology, pull down, two hybrid	Wafa LA (2003), Wafa LA (2003), Wafa LA (2003)	3
SIAH1	2	SNCA	0	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Lee JT (2008), Lee JT (2008), Rott R (2008), Rott R (2008), Szargel R (2009), Szargel R (2009), Szargel R (2009), Szargel R (2009), Szargel R (2016)	9
DLST	3	EEF1D	3	affinity chromatography technology	Malty RH (2017)	1
PPP1CC	2	PPP1R13B	9	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Esteves SL (2012), Fardilha M (2011), Huttlin EL (2015), Hauri S (2013), St-Denis N (2016), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	8
NFE2L2	1	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Baba K (2013), Baba K (2013)	2
PML	7	SIAH1	2	affinity chromatography technology	Kraemer OH (2008)	1
SIAH2	0	USP13	2	affinity chromatography technology, pull down	Scortegagna M (2011), Scortegagna M (2011)	2
SKI	3	SIAH2	0	affinity chromatography technology	Zhao HL (2010)	1
TINF2	1	EEF1D	3	two hybrid	Lee OH (2011)	1
SIAH2	0	XAF1	1	affinity chromatography technology, genetic interference, two hybrid, affinity chromatography technology	Lee MG (2014), Lee MG (2014), Lee MG (2014), Lee MG (2014)	4
SIAH1	2	DLD	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIAH2	0	CHEK2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study	Garcia-Limones C (2016), Garcia-Limones C (2016), Garcia-Limones C (2016), Garcia-Limones C (2016), Garcia-Limones C (2016), Garcia-Limones C (2016)	6
KAT5	1	TNK2	7	affinity chromatography technology	Peng L (2012)	1
SIAH2	0	TPX2	4	two hybrid, affinity chromatography technology	Szczepanowski M (2007), Szczepanowski M (2007)	2
AR	3	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Matsuda T (2001), Ueda T (2002), Yamamoto T (2003), Yamamoto T (2003)	4
SKI	3	HIPK2	0	pull down, pull down, affinity chromatography technology	Harada J (2003), Harada J (2003), Harada J (2003)	3
SIAH2	0	STAT3	0	two hybrid	Wang J (2011)	1
4985	0	SIAH1	2	affinity chromatography technology	Petko J (2013)	1
PEG10	2	SIAH2	0	two hybrid, pull down	Okabe H (2003), Okabe H (2003)	2
EGLN3	0	AKAP1	3	affinity chromatography technology	Rodriguez J (2016)	1
HIPK2	0	PML	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	de la Vega L (2011), Renner F (2010), Sung KS (2011), Sung KS (2011), Gresko E (2009), Gresko E (2009), Gresko E (2009)	7
MCM2	3	UBE2D3	1	affinity chromatography technology	Drissi R (2015)	1
SIAH2	0	ZYX	2	pull down, affinity chromatography technology, affinity chromatography technology	Ma B (2016), Ma B (2016), Ma B (2016)	3
PRR20E	0	SIAH1	2	affinity chromatography technology	Huttlin EL (2017)	1
UBE2I	0	UBE2D2	0	biochemical	Wan C (2015)	1
XAF1	1	TRAF2	1	affinity chromatography technology	Lin B (2016)	1
SIAH2	0	KAT5	1	affinity chromatography technology	Grishina I (2012)	1
SIAH1	2	EEF1D	3	pull down, affinity chromatography technology, two hybrid, two hybrid	Wu H (2011), Wu H (2011), Wang J (2011), Rolland T (2014)	4
UBE2I	0	HIPK2	0	two hybrid, two hybrid, two hybrid, pull down, two hybrid, enzymatic study	Lee BH (2003), Bandyopadhyay S (2010), Sung KS (2005), Sung KS (2005), Hofmann TG (2005), Sung KS (2005)	6
OPRM1	0	4985	0	affinity chromatography technology, affinity chromatography technology	Gomes I (2000), He SQ (2011)	2
MCM2	3	SIAH2	0	affinity chromatography technology	Drissi R (2015)	1
SIAH1	2	TNK2	7	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Buchwald M (2012), Buchwald M (2012), Buchwald M (2012), Wang J (2011)	4
SIAH1	2	PLCE1	2	affinity chromatography technology	Yun S (2008)	1
SIAH2	0	LATS2	1	affinity chromatography technology, affinity chromatography technology	Ma B (2016), Ma B (2016)	2
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
SIAH1	2	PIAS3	2	pull down	Depaux A (2007)	1
KAT5	1	UBE2I	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng Z (2008), Cheng Z (2008), Cheng Z (2008)	3
PSMD4	1	DLD	1	affinity chromatography technology, affinity chromatography technology	Weekes J (2003), Malty RH (2017)	2
ATN1	2	SIAH1	2	two hybrid, two hybrid	Lim J (2006), Wang J (2011)	2
MCM2	3	EEF1D	3	affinity chromatography technology	Drissi R (2015)	1
EGLN3	0	PRICKLE3	2	affinity chromatography technology	Rodriguez J (2016)	1
TRAF2	1	UBE2D1	0	pull down	Alvarez SE (2010)	1
EGLN3	0	SPRY2	4	affinity chromatography technology	Anderson K (2011)	1
SIAH2	0	UBE2D1	0	pull down, pull down, pull down	Rott R (2008), Uchiki T (2009), Fan L (2015)	3
HDAC3	5	SKI	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim YB (2007), Zhao HL (2009), Tabata T (2009), Ueki N (2008), Ueki N (2008)	5
KAT2B	2	HDAC3	5	pull down, affinity chromatography technology	Gregoire S (2007), Gregoire S (2007)	2
HIPK2	0	SIAH1	2	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Calzado MA (2009), Winter M (2008), Winter M (2008), Winter M (2008), Kim SY (2009), Kim SY (2009), Kim SY (2009), Kim SY (2009), Kurokawa K (2013)	13
UBE2I	0	PIAS2	2	two hybrid, two hybrid, two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down	Rual JF (2005), Lee BH (2003), Bandyopadhyay S (2010), Schmidt D (2002), Wang J (2011), Rolland T (2014), Saul VV (2014), van den Akker E (2005), Schmidt D (2002)	9
UBE2I	0	HIPK3	5	two hybrid	Bandyopadhyay S (2010)	1
SIAH2	0	UBE2D3	1	pull down	Stebbins JL (2013)	1
EGLN3	0	EGLN1	3	affinity chromatography technology	Nakayama K (2007)	1
SIAH2	0	SNCAIP	2	enzymatic study	Avraham E (2005)	1
EGLN2	4	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Nakayama K (2007), Nakayama K (2004)	2
SIAH1	2	SIAH2	0	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Depaux A (2006), Depaux A (2006), Depaux A (2006), Huttlin EL (2017)	5
DCC	3	SIAH1	2	pull down	Hu G (1999)	1
TYK2	1	VAV1	2	affinity chromatography technology	Adam L (2000)	1
SIAH1	2	PIAS2	2	two hybrid	Depaux A (2007)	1
SIAH2	0	KAT2B	2	affinity chromatography technology	Grishina I (2012)	1
MCM2	3	UBE2L6	0	affinity chromatography technology	Drissi R (2015)	1
SIAH2	0	EAF2	1	affinity chromatography technology, affinity chromatography technology	Yu X (2016), Yu X (2016)	2
PPP1R13B	9	LATS2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Vigneron AM (2010), Vigneron AM (2010), Aylon Y (2010), Aylon Y (2010), Couzens AL (2013)	5
UBE2L6	0	SIAH1	2	pull down	Kraemer OH (2008)	1
LATS2	1	SIAH1	2	affinity chromatography technology, affinity chromatography technology	Xiang L (2014), Xiang L (2014)	2
PRICKLE3	2	SIAH2	0	affinity chromatography technology	Huttlin EL (2017)	1
PIAS2	2	PML	7	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Cuchet-Lourenco D (2011), Rabellino A (2012), Rabellino A (2012), Rabellino A (2012)	4
KAT2B	2	UBE2D2	0	pull down	Morgan JE (2017)	1
CEBPD	0	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Sarkar TR (2012), Sarkar TR (2012)	2
AR	3	PIAS2	2	two hybrid, two hybrid, pull down, pull down	Kotaja N (2000), Moilanen AM (1999), Moilanen AM (1999), Kotaja N (2000)	4
EGLN1	3	SIAH2	0	affinity chromatography technology, affinity chromatography technology	Nakayama K (2007), Nakayama K (2004)	2
PIAS2	2	TRAF2	1	pull down, affinity chromatography technology, affinity chromatography technology	Liu J (2011), Liu J (2011), Liu J (2011)	3
SIAH1	2	TP53BP2	5	two hybrid, two hybrid	Wang J (2011), Rolland T (2014)	2
MCM2	3	UBE2D1	0	affinity chromatography technology	Drissi R (2015)	1
AR	3	KAT2B	2	pull down, enzymatic study	Fu M (2000), Fu M (2000)	2
MCM2	3	SIAH1	2	affinity chromatography technology	Drissi R (2015)	1
DCC	3	SIAH2	0	two hybrid	Hu G (1997)	1
SIAH2	0	RBBP8	1	pull down	Germani A (2003)	1
SH3RF1	1	UBE2D3	1	pull down, pull down	Votteler J (2009), Tuvia S (2007)	2
SPRY2	4	EGLN2	4	affinity chromatography technology, affinity chromatography technology	Anderson K (2011), Anderson K (2011)	2
UBE2D2	0	SIAH1	2	two hybrid, two hybrid, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Szargel R (2009), Winter M (2008)	4
SIAH2	0	UBE2I	0	two hybrid, two hybrid, two hybrid	Depaux A (2007), Hu G (1997), Wang J (2011)	3
USP19	1	SIAH1	2	two hybrid, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, unspecified method	Altun M (2012), Velasco K (2013), Velasco K (2013), Zhang Q (2017), Zhang Q (2017), Zhang Q (2017)	6
SIAH1	2	STAT3	0	two hybrid, affinity chromatography technology	Wang J (2011), Shin M (2016)	2
LATS2	1	TP53BP2	5	bioid	Couzens AL (2013)	1
SIAH2	0	DLST	3	pull down, affinity chromatography technology, affinity chromatography technology	Habelhah H (2004), Habelhah H (2004), Habelhah H (2004)	3
UBE2I	0	PIAS1	4	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down	Lee BH (2003), Sapetschnig A (2002), Kahyo T (2001), Bandyopadhyay S (2010), Driscoll JJ (2010), Kahyo T (2001), Yin Y (2012), Gocke CB (2005), van den Akker E (2005), Ogawa H (2009), Schmidt D (2002), Gibbs-Seymour I (2015)	12
DLD	1	DLST	3	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
EGLN3	0	PPP1CC	2	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	PSMD4	1	affinity chromatography technology	Rodriguez J (2016)	1
PPP1CC	2	PIAS1	4	two hybrid	Esteves SL (2012)	1