PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CUL5	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ehrlich ES (2009), Ehrlich ES (2009), Bennett EJ (2010)	3
CCNE1	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Harbour JW (1999), Manenti S (1999), Horton LE (1997), Higashi H (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999)	9
MYC	2	RUVBL1	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Fuchs M (2001), Park J (2002), Park J (2002), Koch HB (2007)	4
EP300	36	FOXO3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li XN (2009), Li XN (2009), Mahmud DL (2002), Li X (2015)	4
CDH1	4	TRIM25	5	bioid	Guo Z (2014)	1
HSP90AA1	7	FBXW2	0	affinity chromatography technology	Taipale M (2012)	1
LATS2	1	SKP1	0	affinity chromatography technology	Couzens AL (2013)	1
CKS1B	0	KMT2A	58	affinity chromatography technology, affinity chromatography technology	Grey W (2018), Grey W (2018)	2
BTRC	1	E2F1	0	enzymatic study	Ohta T (2001)	1
CDC14B	1	FZR1	1	affinity chromatography technology	Bassermann F (2008)	1
SMTNL2	3	CDK2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDH1	4	KANK2	4	bioid	Guo Z (2014)	1
ATM	9	SMAD7	1	affinity chromatography technology	Zhang S (2006)	1
SKP2	2	TRIM21	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Sabile A (2006), Sabile A (2006), Sabile A (2006), Sabile A (2006), Sabile A (2006)	5
EP300	36	MRE11	3	affinity chromatography technology	Jung SY (2005)	1
AURKB	2	SUGT1	1	affinity chromatography technology	Huttlin EL (2017)	1
NXF1	0	USP18	1	affinity chromatography technology	Castello A (2012)	1
LATS2	1	ALMS1	13	bioid	Couzens AL (2013)	1
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
SKP2	2	WEE1	2	affinity chromatography technology	Watanabe N (2004)	1
TCF3	7	EP300	36	biochemical, affinity chromatography technology, enzymatic study, genetic interference, enzymatic study, pull down	Bradney C (2003), Bradney C (2003), Bradney C (2003), Bradney C (2003), Hyndman BD (2012), Kim JY (2004)	6
CUL2	3	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015)	3
CUL5	1	ELOC	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology	Kamura T (2001), Nishiya T (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Kershaw NJ (2014), Huttlin EL (2017)	18
AKT1	1	FOXO1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique	Matsuzaki H (2005), Brent MM (2008), Rena G (1999), Tang ED (1999), Chen TC (2014)	5
SP1	0	TAL1	0	pull down, two hybrid, affinity chromatography technology	Lecuyer E (2002), Lecuyer E (2002), Lecuyer E (2002)	3
ESR1	0	FOXO1	2	two hybrid, pull down, two hybrid, pull down, affinity chromatography technology	Schuur ER (2001), Schuur ER (2001), Zhao HH (2001), Zhao HH (2001), Castoria G (2012)	5
BTRC	1	RASSF1	3	two hybrid, affinity chromatography technology, bioid, affinity chromatography technology	Vinayagam A (2011), Zhou X (2012), Coyaud E (2015), Huttlin EL (2017)	4
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
RBX1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Ohta T (2001), Saiga T (2009), Rodier G (2008), Zhou W (2014), Zhou W (2014)	6
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
HSP90AA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
USP19	1	TRIM21	0	affinity chromatography technology	Sowa ME (2009)	1
PSMD9	0	YY1	7	pull down	Wan M (2012)	1
CEBPA	0	CDK2	0	biochemical, affinity chromatography technology, pull down, affinity chromatography technology	Wang H (2001), Wang H (2001), Wang H (2001), Wang GL (2004)	4
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
STUB1	4	RUNX2	2	affinity chromatography technology, two hybrid	Li X (2008), Li X (2008)	2
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
BRCA1	7	ALMS1	13	affinity chromatography technology	Ertych N (2016)	1
ELAVL1	0	90378	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CDH1	4	FAM83H	6	bioid	Guo Z (2014)	1
FZR1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIM1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mizuno K (2001), Mizuno K (2001), Mizuno K (2001), Shay KP (2005), Shay KP (2005)	5
FBXW2	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Xu J (2017), Xu J (2017), Xu J (2017), Huttlin EL (2017)	4
TAL1	0	EP300	36	affinity chromatography technology, pull down, pull down, enzymatic study, pull down, pull down	Huang S (1999), Huang S (1999), Huang S (1999), Huang S (2000), Huang S (2000), Qiu Y (2002)	6
COPS5	0	ESR1	0	affinity chromatography technology	Callige M (2005)	1
BTRC	1	SIRT2	1	bioid	Coyaud E (2015)	1
CCNE1	1	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Shanahan F (1999), Connor MK (2003), Connor MK (2003), Jeon Y (2007), Bustany S (2011), Xu X (1999), Xu X (1999), Datta NS (1998), Orend G (1998), Liu J (1997), Sheaff RJ (1997), Sheaff RJ (1997), Bresnahan WA (1996), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Ciarallo S (2002), Ciarallo S (2002), Chu I (2007), Chu I (2007), Chen J (1996), Levkau B (1998), Larrea MD (2009), Grimmler M (2007), Chen TC (2014), Qiu H (2016)	26
GPS1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Stotland A (2012), Huang X (2005), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
SKP2	2	IQSEC1	3	affinity chromatography technology	Huttlin EL (2017)	1
SMTNL2	3	CUL1	7	affinity chromatography technology	Huttlin EL (2017)	1
CUL1	7	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Michel JJ (1998)	2
PHB	0	E2F1	0	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joshi B (2003), Joshi B (2003), Fusaro G (2003), Fusaro G (2003), Wang S (2002), Wang S (2002), Wang S (1999), Wang S (1999), Wang S (2004), Wang S (2004)	10
HSP90AA1	7	SKP1	0	pull down	Zhang M (2008)	1
CCNE1	1	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
BRCA1	7	AR	3	pull down, pull down, two hybrid	Park JJ (2000), Yeh S (2000), Yeh S (2000)	3
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
PPP1CA	3	AURKB	2	affinity chromatography technology	Flores-Delgado G (2007)	1
ATM	9	E2F1	0	enzymatic study	Lin WC (2001)	1
CDT1	2	GMNN	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2008), Ballabeni A (2004), Nishitani H (2004), Nishitani H (2004), Teer JK (2008), Roukos V (2007), Wong PG (2010), Sugimoto N (2004), Takeda DY (2005), Ramachandran N (2004), Higa LA (2003), Higa LA (2003), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	15
ELAVL1	0	CDK9	3	affinity chromatography technology	Abdelmohsen K (2009)	1
SKP2	2	SIRT4	0	pull down	Inuzuka H (2012)	1
CDC20	1	ANAPC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Hein JB (2014), Lischetti T (2014), Kelly A (2014), Craney A (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	8
CCNA2	1	SKP1	0	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	RAD50	3	biochemical, biochemical, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Greenberg RA (2006), Chen L (2008), Hill SJ (2014), Acharya S (2014)	10
TRIM25	5	IQSEC1	3	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	SKP2	2	affinity chromatography technology	Chew EH (2007)	1
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
EP300	36	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Kim RH (2000), Luciakova K (2008), Janknecht R (1998), Chung CL (2011), Shen X (1998), Dornan D (2003), Yang Y (2015)	7
HSP90AA1	7	USP19	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Gano JJ (2010), Lee JG (2014), Lee JG (2014), Lee JG (2014), He WT (2016), He WT (2016), He WT (2016)	7
CDK1	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEBPA	0	GFAP	0	affinity chromatography technology	Bararia D (2008)	1
TWIST1	0	BRAP	0	affinity chromatography technology	Yang F (2012)	1
RBX1	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Dias DC (2002), Ohta T (1999), Ohta T (1999), Maine GN (2007), Hu J (2004), Furukawa M (2002), Mao X (2011), Sufan RI (2006), Sufan RI (2006), Sufan RI (2006), Brower CS (2002), Tron AE (2012), Kamura T (2004), Kristensen AR (2012), Costessi A (2011), Huang DT (2009), Kamura T (1999), Kamura T (1999), Xu J (2015), Cardote TAF (2017)	20
CUL1	7	SNRPB2	2	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	STK3	1	enzymatic study	Chen X (2016)	1
SKP2	2	WDR59	3	affinity chromatography technology	Huttlin EL (2017)	1
CCNB1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Di Fiore B (2010), Nishiyama A (2000), Wolthuis R (2008), Desai D (1995), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
FBXW2	0	EP300	36	affinity chromatography technology	Kimbrel EA (2009)	1
SKP2	2	CCDC88A	3	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1B	1	SIRT6	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zhao G (2016), Zhao G (2016), Zhao G (2016), Zhao G (2016)	4
MYC	2	CUL1	7	affinity chromatography technology	von der Lehr N (2003)	1
WEE1	2	YWHAB	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Wang Y (2000), Jin J (2004)	3
AURKB	2	UBB	4	affinity chromatography technology	Fogeron ML (2013)	1
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
COPS5	0	CKS1B	0	affinity chromatography technology	Bennett EJ (2010)	1
CCNA2	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
PHB	0	YWHAB	1	affinity chromatography technology	Zhu B (2010)	1
BRCA1	7	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu Y (2012), Lu Y (2012), Parameswaran B (2015)	3
LATS2	1	CEP192	5	bioid	Couzens AL (2013)	1
NXF1	0	CUL5	1	affinity chromatography technology	Castello A (2012)	1
TRIM25	5	MYC	2	affinity chromatography technology	Choudhury NR (2017)	1
BTG1	1	SKP1	0	affinity chromatography technology	Sasajima H (2012)	1
CCNB1	3	EP300	36	pull down, affinity chromatography technology	Felzien LK (1998), Felzien LK (1998)	2
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
NXF1	0	MTOR	14	affinity chromatography technology	Castello A (2012)	1
HSP90AA1	7	RRM2	2	affinity chromatography technology	Truman AW (2015)	1
CDC34	3	CUL2	3	pull down	Sandoval D (2014)	1
TRIM49	6	CUL1	7	affinity chromatography technology	Huttlin EL (2015)	1
CCNE1	1	AR	3	affinity chromatography technology	Yamamoto A (2000)	1
DDB1	6	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Jin J (2006), Emberley ED (2012)	3
GMNN	0	CDH1	4	affinity chromatography technology	Tsunematsu T (2013)	1
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
PPP1CA	3	AKT1	1	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li L (2003), Xiao L (2010), Xiao L (2010), Xiao L (2010), Chen CS (2005), Chen CS (2005)	6
SKP2	2	DDX11	1	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	CCNA1	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique	Zheleva DI (2002), Ramachandran N (2004), Rohaly G (2005), Heron-Milhavet L (2006), Chen TC (2014)	5
PFDN5	0	SP1	0	affinity chromatography technology	Yoshida T (2008)	1
SKP2	2	TOB1	1	affinity chromatography technology, affinity chromatography technology	Hiramatsu Y (2006), Hiramatsu Y (2006)	2
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
SP1	0	MEF2D	5	affinity chromatography technology, pull down	Park SY (2002), Park SY (2002)	2
CEP192	5	ALMS1	13	affinity chromatography technology, bioid	Gomez-Ferreria MA (2012), Firat-Karalar EN (2014)	2
STK3	1	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Romano D (2010), Romano D (2010), Kim D (2010), Kim D (2010), Kim D (2010)	5
TRIM25	5	HSP90AA1	7	affinity chromatography technology	Choudhury NR (2017)	1
SMAD4	9	YY1	7	imaging technique, pull down, affinity chromatography technology	Kurisaki K (2003), Kurisaki K (2003), Kurisaki K (2003)	3
CCNA1	3	MYBL2	2	affinity chromatography technology, pull down, enzymatic study	Mueller-Tidow C (2001), Mueller-Tidow C (2001), Johnson TK (1999)	3
CUL4A	2	SUGT1	1	biochemical	Havugimana PC (2012)	1
KMT2A	58	ELOC	0	affinity chromatography technology	Wang J (2012)	1
CCNE1	1	SKP2	2	pull down, enzymatic study	Yeh KH (2001), Enchev RI (2012)	2
NLK	1	SKP2	2	affinity chromatography technology	Kanei-Ishii C (2008)	1
CDT1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Hu J (2004), Hu J (2004), Hu J (2004), Hu J (2004), Zhang Y (2012)	5
BRCA1	7	SF3B3	4	affinity chromatography technology	Ertych N (2016)	1
SIRT6	2	TUBB3	3	affinity chromatography technology	Huttlin EL (2017)	1
ESR1	0	RAD50	3	affinity chromatography technology	Han SJ (2016)	1
SLC9A3R1	2	AKT1	1	affinity chromatography technology, enzymatic study	Song GJ (2015), Song GJ (2015)	2
CDH1	4	KIAA1671	0	bioid	Guo Z (2014)	1
SKP2	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Bennett EJ (2010)	2
STUB1	4	UBE2L3	1	pull down	Hampe C (2006)	1
GMNN	0	CDKN1A	1	pull down	Ramachandran N (2004)	1
MYCN	2	SKP2	2	affinity chromatography technology	Cowling VH (2008)	1
FZR1	1	GMNN	0	affinity chromatography technology, enzymatic study, pull down	Pfleger CM (2001), Williamson A (2011), Williamson A (2011)	3
LATS2	1	RASSF1	3	fluorescent resonance energy transfe, pull down, fluorescent resonance energy transfe	Mo XL (2015), Mo XL (2015), Ivanov AA (2017)	3
STIL	3	SUGT1	1	bioid	Gupta GD (2015)	1
CUL4A	2	BTRC	1	affinity chromatography technology	He YJ (2006)	1
PPP1CA	3	CDK2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
SMAD4	9	WEE1	2	genetic interference	Shen JP (2017)	1
CCNA1	3	CDK2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, imaging technique	Sweeney C (1996), Yang R (1997), Yang R (1997), Mueller-Tidow C (2001), Brown NR (1999), Niida H (2005), Yam CH (2000), Wang H (2009), Narayanan R (2005), Harwell RM (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Peiretti A (2003), Pan ZQ (1993), Kim KS (2002), Lyapina SA (1998), Desai D (1995), Thomas DM (2004), Johnson LN (2002), Rohaly G (2005), Chen TC (2014)	22
ASB2	1	DCUN1D3	1	affinity chromatography technology	Huttlin EL (2017)	1
ELAVL1	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Abdelmohsen K (2009), Datta K (2005), Datta K (2005), Yuen JS (2007)	4
CUL5	1	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
CCNA2	1	BRCA1	7	affinity chromatography technology, pull down	Ruffner H (1999), Wang H (1997)	2
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
SKP2	2	90378	0	affinity chromatography technology	Huttlin EL (2017)	1
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
TRPC4AP	4	SKP2	2	affinity chromatography technology, affinity chromatography technology	Jamal A (2015), Jamal A (2015)	2
VHL	0	AR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen S (2013), Chen S (2013), Wang J (2014), Wang J (2014)	4
SKP2	2	TAL1	0	affinity chromatography technology	Nie L (2008)	1
GMNN	0	IMPDH1	2	two hybrid	Wang J (2011)	1
EP300	36	ESR1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Fajas L (2002), Fan S (2002), Fan S (2002), Fan S (2002), Kang YK (2002), Kang YK (2002), Hao L (2010), Jin W (2008), Cui Y (2006), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Kim SH (2010), Ma Y (2010), Ma Y (2010), Fujita T (2003), Likhite VS (2004), Band AM (2011), Loven MA (2004), Nalvarte I (2010), Yi P (2015)	21
SKP2	2	AR	3	imaging technique, affinity chromatography technology	Li B (2014), Li B (2014)	2
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
SKP2	2	OFD1	3	affinity chromatography technology	Huttlin EL (2017)	1
SIRT2	1	CDC20	1	enzymatic study	Kim HS (2011)	1
CCNA2	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Higashi H (1996), Knudsen ES (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Nakanishi M (1999)	7
FZR1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Lv XB (2010), Lv XB (2010)	2
TP73	2	CUL1	7	affinity chromatography technology	Peschiaroli A (2009)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
SKP2	2	CCNB1	3	affinity chromatography technology	Bashir T (2010)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
CDT1	2	CCNA2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teer JK (2008), Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
CUL4A	2	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Bennett EJ (2010), Huttlin EL (2017)	4
CEBPA	0	RB1	2	affinity chromatography technology, affinity chromatography technology	Bararia D (2008), Wang GL (2004)	2
COPS5	0	ELOC	0	affinity chromatography technology	Bennett EJ (2010)	1
SKP2	2	ZNF507	5	affinity chromatography technology	Huttlin EL (2017)	1
BTRC	1	PFDN5	0	bioid	Coyaud E (2015)	1
SKP2	2	USP19	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
TWIST1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Guo W (2016), Guo W (2016), Guo W (2016), Zhong J (2013), Ruan D (2017)	5
MYC	2	MYCN	2	affinity chromatography technology	Li X (2015)	1
KPNA1	5	RUVBL1	2	affinity chromatography technology	Hein MY (2015)	1
SP1	0	AR	3	affinity chromatography technology, affinity chromatography technology	Yuan H (2005), Chen PH (2008)	2
MYC	2	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Faiola F (2005), Zhang K (2005), Covic M (2005), Fujii M (2006)	8
CDKN1C	0	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhao R (2013), Zhao R (2013), Zhao R (2013)	3
EP300	36	TWIST1	0	affinity chromatography technology, pull down, pull down, genetic interference	Hamamori Y (1999), Hamamori Y (1999), Hamamori Y (1999), Hamamori Y (1999)	4
SKP2	2	NBN	1	affinity chromatography technology, affinity chromatography technology	Wu J (2012), Wu J (2012)	2
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
TRIM25	5	ELAVL1	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
CUL1	7	SF3B3	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Cordero-Espinoza L (2013), Cordero-Espinoza L (2013)	3
EP300	36	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji W (2014), Ianari A (2004), Aoki I (2012)	3
OFD1	3	RRM2	2	bioid	Gupta GD (2015)	1
SIRT6	2	TRIM25	5	affinity chromatography technology	Simeoni F (2013)	1
TCF3	7	SLC9A3R1	2	affinity chromatography technology	Teachenor R (2012)	1
RASSF1	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SPDYA	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Dinarina A (2009), Dinarina A (2009)	2
SKP2	2	ANAPC1	1	affinity chromatography technology	Huttlin EL (2017)	1
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
COPS5	0	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
CCNB1	3	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Amador V (2007), Garcia-Wilson E (2005), Ando T (2001), Poon RY (1996), Fogeron ML (2013), Chen TC (2014)	6
NXF1	0	KDM5C	9	affinity chromatography technology	Castello A (2012)	1
PHB	0	RBL2	5	two hybrid, pull down, affinity chromatography technology	Wang S (1999), Wang S (1999), Wang S (1999)	3
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
SP1	0	ESR1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Koslowski M (2009), Jin W (2008), Dong J (2006), Dong J (2006), Castet A (2006), He S (2005), He S (2005), Varshochi R (2005), Varshochi R (2005), Petz LN (2004), Li D (2007), Itoh Y (2007), Saville B (2000), Gibson LL (2005)	14
IMPDH2	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
SMAD4	9	FOXO1	2	affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Seoane J (2004)	2
CDKN1B	1	KPNA1	5	pull down, affinity chromatography technology, unspecified method	Sekimoto T (2004), Sekimoto T (2004), Sekimoto T (2004)	3
SKP2	2	NDRG1	2	affinity chromatography technology	Wang Y (2017)	1
PFDN5	0	MYC	2	pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mori K (1998), Mori K (1998), Fujioka Y (2001), Satou A (2001), Lubyova B (2007), Narita R (2012), Narita R (2012), Watanabe K (2002)	8
TRIM25	5	NDRG1	2	affinity chromatography technology	Choudhury NR (2017)	1
BRAP	0	UBB	4	two hybrid	Fatima S (2015)	1
SP1	0	CDK1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Yang HC (2014), Yang HC (2014)	6
RB1	2	AR	3	pull down, pull down, two hybrid, affinity chromatography technology	Lu J (1998), Yeh S (1998), Yeh S (1998), Gamble SC (2007)	4
CUL2	3	BRAP	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	CDT1	2	biochemical	He YJ (2006)	1
TWIST1	0	CUL4A	2	imaging technique	Govindarajalu G (2018)	1
MYC	2	TRIM21	0	affinity chromatography technology	Agrawal P (2010)	1
HSP90AA1	7	SF3B3	4	affinity chromatography technology	Taipale M (2012)	1
YY1	7	RB1	2	affinity chromatography technology	Hu HM (2007)	1
TRIM25	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
MTOR	14	RUVBL1	2	affinity chromatography technology	Agrawal P (2012)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
BARD1	4	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ryser S (2009), Ryser S (2009), Bosse KR (2012)	3
CDK3	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
ATM	9	MRE11	3	unspecified method, biochemical, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Falck J (2005)	3
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
YY1	7	MYC	2	two hybrid, pull down	Shrivastava A (1993), Shrivastava A (1993)	2
CCNA2	1	CDKN1C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
CUL4A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
AKT1	1	CCDC88A	3	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Enomoto A (2005), Enomoto A (2005), Anai M (2005), Anai M (2005), Anai M (2005)	5
CDH1	4	MRE11	3	bioid	Guo Z (2014)	1
CDC34	3	BTRC	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, bioid, affinity chromatography technology	Semplici F (2002), Cenciarelli C (1999), Sowa ME (2009), Fernandez-Sanchez ME (2010), Chong RA (2014), Burrows AC (2012), Coyaud E (2015), Huttlin EL (2017)	8
LATS2	1	AURKB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yabuta N (2011), Yabuta N (2011), Yabuta N (2011)	3
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	FOXO1	2	imaging technique	Chen TC (2014)	1
RB1	2	CCNA1	3	pull down, affinity chromatography technology, enzymatic study	Yang R (1999), Yang R (1999), Zarkowska T (1997)	3
TOB1	1	SMAD4	9	affinity chromatography technology	Yoshida Y (2000)	1
PIM1	2	MYC	2	affinity chromatography technology, affinity chromatography technology	Zippo A (2007), Zippo A (2007)	2
ESR1	0	STUB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Tateishi Y (2004), Tateishi Y (2004), Berry NB (2008), Dhamad AE (2016)	6
E2F1	0	CCNA1	3	pull down, affinity chromatography technology, pull down	Yang R (1999), Yang R (1999), Ji P (2006)	3
LATS2	1	CDKN1A	1	enzymatic study	Suzuki H (2013)	1
VHL	0	IMPDH2	3	affinity chromatography technology	Ewing RM (2007)	1
TRIM25	5	SKP2	2	affinity chromatography technology	Choudhury NR (2017)	1
PPP1CA	3	CUL1	7	affinity chromatography technology	Flores-Delgado G (2007)	1
GPS1	1	SKP2	2	affinity chromatography technology	Lyapina S (2001)	1
SKP2	2	MEF2C	16	affinity chromatography technology, affinity chromatography technology	Di Giorgio E (2015), Di Giorgio E (2015)	2
MEF2C	16	EP300	36	genetic interference, pull down	Sartorelli V (1997), Sartorelli V (1997)	2
SKP2	2	DCUN1D3	1	affinity chromatography technology	Zhang S (2016)	1
NXF1	0	RUVBL1	2	affinity chromatography technology	Castello A (2012)	1
RRM2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIRT6	2	ANAPC1	1	affinity chromatography technology	Simeoni F (2013)	1
SKP2	2	RAD50	3	affinity chromatography technology	Wu J (2012)	1
SAMHD1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014), Huttlin EL (2017)	3
PFDN5	0	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
NXF1	0	CEP192	5	affinity chromatography technology	Castello A (2012)	1
NXF1	0	MEF2D	5	affinity chromatography technology	Castello A (2012)	1
RASSF1	3	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FOXB1	1	YY1	7	affinity chromatography technology	Li X (2015)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP19	1	CDK1	0	affinity chromatography technology	Sowa ME (2009)	1
NXF1	0	SP1	0	affinity chromatography technology	Castello A (2012)	1
CDK3	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
YWHAB	1	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down	Lin HK (2009), Lin HK (2009), Lin HK (2009)	3
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
SMAD7	1	CDH1	4	affinity chromatography technology	Tang Y (2008)	1
COPS6	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
NXF1	0	E2F1	0	affinity chromatography technology	Castello A (2012)	1
CDKN1B	1	CCNA1	3	pull down, affinity chromatography technology	Ji P (2006), Thomas DM (2004)	2
DCUN1D3	1	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
HSP90AA1	7	TRIM49	6	affinity chromatography technology	Taipale M (2012)	1
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
WEE1	2	RB1	2	genetic interference	Srivas R (2016)	1
TRIM25	5	SF3B3	4	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	KIAA1671	0	affinity chromatography technology	Huttlin EL (2017)	1
CKS1B	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	CUL4A	2	affinity chromatography technology	Choudhury NR (2017)	1
BTRC	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Strack P (2000), Margottin F (1998), Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Watanabe N (2004), Wu G (2003), Kawakami T (2001), Hattori K (1999), Hattori K (1999), Hattori K (1999), Kitagawa M (1999), Hart M (1999), Su Y (2008), Banerjee S (2010), Winston JT (1999), Winston JT (1999), Estrabaud E (2007), Latres E (1999), Latres E (1999), Liu J (2004), Lievens S (2009), Yoshida Y (2007), Yoshida Y (2007), Busino L (2012), Li T (2005), da Silva Almeida AC (2013), Sahasrabuddhe AA (2014), Choi BH (2014), Chong RA (2014), Kim TY (2014), Coyaud E (2015), Deng W (2015), Coyaud E (2015), Liu YQ (2015), He N (2005), Kuchay S (2017), Hauri S (2016)	40
CDT1	2	CUL1	7	affinity chromatography technology	Li X (2003)	1
CDT1	2	FOXO3	1	pull down, pull down	Zhang Y (2012), Zhang Y (2012)	2
SMTNL2	3	YWHAB	1	affinity chromatography technology	Huttlin EL (2017)	1
SMAD4	9	AKT1	1	affinity chromatography technology	Song K (2006)	1
ESR1	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nair SC (1996), Lee MO (2002), Fan M (2005), Tateishi Y (2004), Fiskus W (2007), Powell E (2010), Suzuki T (2011), Berry NB (2008), Sumanasekera WK (2003), Taipale M (2012), Donley C (2013), Donley C (2013), Dhamad AE (2016)	13
CDK2	0	LATS2	1	enzymatic study	Toji S (2004)	1
SKP2	2	RAG2	0	unspecified method, enzymatic study	Jiang H (2005), Jiang H (2005)	2
CDC20	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Huttlin EL (2017)	3
RBX1	2	ELOC	0	affinity chromatography technology	Brower CS (2002)	1
SKP1	0	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
RBL2	5	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Li Y (1993), Farkas T (2002), Huttlin EL (2015), Huttlin EL (2017)	4
RBL2	5	SKP2	2	affinity chromatography technology, enzymatic study	Bhattacharya S (2003), Tedesco D (2002)	2
COPS5	0	IMPDH2	3	affinity chromatography technology	Bennett EJ (2010)	1
ASB2	1	RNF7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Bello NF (2009), Zakaria R (2013)	3
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
CUL4A	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Rao F (2014), Rao F (2014), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	13
SKP2	2	RICTOR	4	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	DNAJB5	4	affinity chromatography technology	Huang Z (2004)	1
LATS2	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDH1	4	EP300	36	affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005)	2
AURKB	2	RASSF1	3	enzymatic study	Chow C (2011)	1
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
PPP1CA	3	CDK1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
AURKB	2	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
E2F1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology	Xu M (1994), Xu M (1994), Schulman BA (1998)	3
MTOR	14	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
COPS5	0	FBXL18	5	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	PPP1CA	3	affinity chromatography technology	Koch HB (2007)	1
OFD1	3	CCNB1	3	bioid	Gupta GD (2015)	1
SKP1	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Kumar R (2005), Wang W (2004), Ohta T (2001), Oshikawa K (2003), Liu J (2002), Li X (2003), Zhou W (2014), Zhou W (2014), Hao J (2015), Hauri S (2016)	11
CDK2	0	TRIM21	0	affinity chromatography technology	Neganova I (2011)	1
AR	3	E2F1	0	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
CCNE1	1	TP73	2	enzymatic study, pull down	Gaiddon C (2003), Gaiddon C (2003)	2
CUL5	1	SNRPB2	2	affinity chromatography technology	Bennett EJ (2010)	1
PSMD9	0	BRCA1	7	two hybrid	Hill SJ (2014)	1
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
RNF7	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Duan H (2001), Duan H (2001)	2
ELAVL1	0	RBL2	5	affinity chromatography technology	Abdelmohsen K (2009)	1
GMNN	0	ATM	9	affinity chromatography technology	Hein MY (2015)	1
CDK3	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KDM5C	9	WEE1	2	genetic interference	Shen JP (2017)	1
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
SKP2	2	FBXL18	5	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	SF3B3	4	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
HSP90AA1	7	FAM83H	6	affinity chromatography technology	Gano JJ (2010)	1
CDK3	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
AR	3	LATS2	1	two hybrid, affinity chromatography technology	Powzaniuk M (2004), Powzaniuk M (2004)	2
TCF3	7	RB1	2	affinity chromatography technology, affinity chromatography technology	Vitelli L (2000), Vitelli L (2000)	2
EP300	36	COPS2	5	enzymatic study, pull down	Eckey M (2013), Eckey M (2013)	2
COPS5	0	CDC20	1	affinity chromatography technology	Bennett EJ (2010)	1
CDH1	4	YWHAB	1	bioid	Guo Z (2014)	1
LATS2	1	KIAA1671	0	bioid	Couzens AL (2013)	1
FOXO3	1	YWHAB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Yuan Z (2010), Couzens AL (2013)	3
SKP2	2	MTFR1L	0	affinity chromatography technology	Huttlin EL (2017)	1
RNF126	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhi X (2012), Zhi X (2012), Zhi X (2012)	3
SMTNL2	3	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
AURKB	2	GFAP	0	enzymatic study	Kawajiri A (2003)	1
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
YWHAB	1	RICTOR	4	affinity chromatography technology	Couzens AL (2013)	1
DDB1	6	FBXW8	2	affinity chromatography technology	He YJ (2006)	1
PPP1CA	3	CCNB1	3	affinity chromatography technology	Flores-Delgado G (2007)	1
YWHAB	1	SKIV2L2	0	affinity chromatography technology	Couzens AL (2013)	1
COPS7A	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
NXF1	0	SKP2	2	affinity chromatography technology	Castello A (2012)	1
SIRT2	1	EP300	36	enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Black JC (2008), Han Y (2008), Han Y (2008), Han Y (2008), Delvecchio M (2013)	5
SKP2	2	RASSF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song MS (2008), Song MS (2008), Calvisi DF (2009)	3
FZR1	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Bashir T (2010), Rosner M (2009), Rosner M (2004), Zhang H (1995), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
CUL4A	2	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
COPS5	0	CDKN1B	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Caballero OL (2002), Kouvaraki MA (2006), Kouvaraki MA (2006), Kouvaraki MA (2006), Hsieh YH (2007), Hwang CY (2004), Hwang CY (2004), Pan Y (2012), Wang Y (2008), Wang Y (2008), Yamaguchi F (2008), Wang Y (2014), Zhang H (2017), Zhang H (2017)	14
CUL2	3	GPS1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001)	2
CUL5	1	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Lee JE (2011), Bennett EJ (2010), Lyapina S (2001), Reitsma JM (2017)	6
SKP2	2	UBB	4	affinity chromatography technology	Huttlin EL (2017)	1
CCNE1	1	MYBL2	2	enzymatic study	Johnson TK (1999)	1
MYC	2	FBXW8	2	affinity chromatography technology, affinity chromatography technology, two hybrid	Koch HB (2007), Koch HB (2007), Koch HB (2007)	3
NLK	1	SMAD4	9	two hybrid, affinity chromatography technology	Wang J (2011), Varjosalo M (2013)	2
PPP1CA	3	RB1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Flores-Delgado G (2007), Dunaief JL (2002), Durfee T (1993), Durfee T (1993), Durfee T (1993), Guo C (2007)	6
DDB1	6	NXF1	0	biochemical	Havugimana PC (2012)	1
HSP90AA1	7	SUGT1	1	pull down, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Zhang M (2008), Lee YT (2004), Lee YT (2004), Mayor A (2007), Spiechowicz M (2007), Spiechowicz M (2007), Gano JJ (2010), Niikura Y (2006), Niikura Y (2006), Niikura Y (2006), Liu XS (2012), Goral A (2016), Goral A (2016)	13
ESR1	0	BARD1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dizin E (2010), Dizin E (2010), Liu Y (2015)	3
CCNA2	1	CDC20	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Di Fiore B (2010), Di Fiore B (2010), Di Fiore B (2010), Wolthuis R (2008), Wolthuis R (2008), Ge S (2009), Townsend K (2009), Di Fiore B (2010), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Huttlin EL (2017), Izawa D (2012), Hein JB (2016)	25
ESR1	0	MYC	2	affinity chromatography technology	Cheng AS (2006)	1
BTRC	1	UFD1	1	affinity chromatography technology	Riemer A (2014)	1
YWHAB	1	STK3	1	affinity chromatography technology	Couzens AL (2013)	1
VHL	0	STUB1	4	affinity chromatography technology	Lai Y (2011)	1
KMT2A	58	ASB2	1	affinity chromatography technology	Wang J (2012)	1
CUL1	7	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
TRIM21	0	CDKN1B	1	affinity chromatography technology	Sabile A (2006)	1
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
GFAP	0	NXF1	0	two hybrid	Rolland T (2014)	1
SF3B3	4	SKP2	2	affinity chromatography technology	Cordero-Espinoza L (2013)	1
HSP90AA1	7	SKP2	2	affinity chromatography technology	Taipale M (2012)	1
SLC9A3R1	2	SKP2	2	affinity chromatography technology, far western blotting, unspecified method	Song GJ (2015), Song GJ (2015), Song GJ (2015)	3
SKP2	2	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	FOXO1	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brent MM (2008), Perrot V (2005), Perrot V (2005), Perrot V (2005), Perrot V (2005), Pramanik KC (2014), Pramanik KC (2014), Mahmud DL (2002), Li X (2015)	9
SKP2	2	BTG1	1	affinity chromatography technology, pull down, pull down	Sasajima H (2012), Sasajima H (2012), Sasajima H (2012)	3
RICTOR	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
BTRC	1	CCNE1	1	enzymatic study, enzymatic study	Saha A (2008), Pierce NW (2013)	2
TRIM21	0	CUL1	7	affinity chromatography technology, biochemical, pull down	Sabile A (2006), Sabile A (2006), Sabile A (2006)	3
CCNE1	1	NBN	1	affinity chromatography technology	Stewart GS (2003)	1
MEF2D	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Youn HD (2000), Youn HD (2000)	2
COPS6	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
SP1	0	CCNB1	3	imaging technique, affinity chromatography technology, affinity chromatography technology	Chuang JY (2012), Chuang JY (2012), Yang HC (2014)	3
ELAVL1	0	FOXO3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL1	7	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina SA (1998), Huttlin EL (2015), Huttlin EL (2017)	4
SIRT6	2	RAD50	3	affinity chromatography technology	Simeoni F (2013)	1
CDT1	2	CCNB1	3	affinity chromatography technology, pull down	Sugimoto N (2004), Sugimoto N (2004)	2
DCUN1D3	1	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
VHL	0	ELOC	0	affinity chromatography technology, pull down, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Tsuchiya H (1996), Min JH (2002), Li Z (2002), Hacker KE (2008), Kim BY (2008), Baek JH (2007), Baek JH (2007), Kuznetsova AV (2003), Cockman ME (2000), Lisztwan J (1999), Stickle NH (2004), Lai Y (2011), Liu YV (2007), Norman JA (2006), Kinoshita K (2007), Cai Q (2010), Lai Y (2012), Miller F (2005), Mahrour N (2008), Mahrour N (2008), Russell RC (2011), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Stebbins CE (1999), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	48
CDK9	3	CUL1	7	affinity chromatography technology, affinity chromatography technology	Kiernan RE (2001), Garriga J (2003)	2
HSP90AA1	7	ASB2	1	affinity chromatography technology	Taipale M (2012)	1
HSP90AA1	7	BTRC	1	affinity chromatography technology	Taipale M (2012)	1
SKP2	2	PHLPP1	4	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	STUB1	4	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	PHLPP1	4	affinity chromatography technology	Choudhury NR (2017)	1
SMAD4	9	SMAD7	1	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lebrun JJ (1999), Moren A (2005), Moren A (2005), Moren A (2005), Zhang S (2007), Yan X (2016)	6
PHLPP1	4	SUGT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Sowa ME (2009), Gao G (2013), St-Denis N (2016), St-Denis N (2016), Gangula NR (2013)	5
CDKN1A	1	UBB	4	affinity chromatography technology	Fogeron ML (2013)	1
KMT2A	58	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu H (2010), Liu H (2010), Swarnalatha M (2013)	3
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
SKP2	2	MCM8	3	affinity chromatography technology	Huttlin EL (2017)	1
SIRT3	1	FOXO3	1	affinity chromatography technology	Jacobs KM (2008)	1
SAMHD1	3	RBX1	2	affinity chromatography technology	Morrissey C (2015)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
BRCA1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
DDB1	6	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009)	3
SKP2	2	AP5B1	0	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	SIRT6	2	pull down	Inuzuka H (2012)	1
FOXO3	1	SKP2	2	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Wang F (2011), Wang F (2011), Wu J (2012), Wu J (2012)	4
DDB1	6	TP73	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Malatesta M (2012), Malatesta M (2012), Malatesta M (2012)	3
CDC20	1	CUL1	7	affinity chromatography technology	Wu F (2017)	1
CEBPA	0	SKP2	2	two hybrid	Wang J (2011)	1
BARD1	4	SAMHD1	3	affinity chromatography technology	Woods NT (2012)	1
SKP2	2	SKP1	0	affinity chromatography technology, pull down, pull down, two hybrid, x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Strack P (2000), Ng RW (1998), Ng RW (1998), Schulman BA (2000), Cenciarelli C (1999), Marti A (1999), Sabile A (2006), Ji P (2004), Wang W (2004), Tokarz S (2004), Watanabe N (2004), Lin HK (2009), Lin HK (2009), Lin HK (2009), Price CT (2009), Huang Z (2004), Wu J (2012), Bashir T (2010), Saiga T (2009), Li T (2005), Carrano AC (1999), Wu J (2012), Wu L (2012), Rodier G (2008), Swarnalatha M (2013), Yumimoto K (2013), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Tian X (2015), Liu YQ (2015), Kuchay S (2017), Chan CH (2013), Chan CH (2013), Hauri S (2016), Ma X (2017)	37
COPS6	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC20	1	GMNN	0	affinity chromatography technology, affinity chromatography technology	Pfleger CM (2001), Tsunematsu T (2013)	2
COPS6	0	CCNA2	1	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	McKenzie PP (2003), McKenzie PP (2003), Jeon Y (2007), Derjuga A (2001), Datta NS (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bresnahan WA (1996), Bendjennat M (2003), Bao GC (2006), Chen J (1996), Chen J (1996), Chen J (1996), Levkau B (1998), Poon RY (1996), Zhao J (1998), Wang J (2011), Fogeron ML (2013), Chen TC (2014)	20
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
JAK2	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
TRIM21	0	CDC34	3	pull down	Wada K (2006)	1
CUL5	1	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDC20	1	CCNA1	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Ohtoshi A (2000), Ohtoshi A (2000), Gao D (2009)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
GPS1	1	SKP1	0	affinity chromatography technology	Lyapina S (2001)	1
FBXW8	2	BTRC	1	affinity chromatography technology	Ponyeam W (2012)	1
TAL1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu X (2009), Vitelli L (2000), Vitelli L (2000)	3
ELAVL1	0	TCF3	7	affinity chromatography technology, affinity chromatography technology	Abdelmohsen K (2009), Teachenor R (2012)	2
ASB2	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Nie L (2011), Nie L (2011), Bello NF (2009), Zakaria R (2013), Huttlin EL (2017)	6
TRIM25	5	YY1	7	affinity chromatography technology	Choudhury NR (2017)	1
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
BTRC	1	COPS6	0	affinity chromatography technology	Fang L (2015)	1
SF3B3	4	SKP1	0	affinity chromatography technology	Cordero-Espinoza L (2013)	1
CUL2	3	AR	3	affinity chromatography technology	Chen S (2013)	1
CEP192	5	KIAA1671	0	bioid	Firat-Karalar EN (2014)	1
CDK1	0	BARD1	4	enzymatic study	Hayami R (2005)	1
STIL	3	STUB1	4	bioid	Gupta GD (2015)	1
CCNA1	3	SP1	0	pull down	Fojas de Borja P (2001)	1
BTRC	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	2
NXF1	0	ANAPC1	1	affinity chromatography technology	Castello A (2012)	1
AURKB	2	FZR1	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
CDK1	0	GFAP	0	affinity chromatography technology	Malty RH (2017)	1
IMPDH1	2	WEE1	2	genetic interference	Srivas R (2016)	1
FZR1	1	ANAPC1	1	pull down, unspecified method, affinity chromatography technology	Vodermaier HC (2003), Vodermaier HC (2003), Huttlin EL (2017)	3
SIRT2	1	FZR1	1	enzymatic study	Kim HS (2011)	1
FBXW2	0	SKP1	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Busino L (2012), Saiga T (2009), Watanabe N (2004), Winston JT (1999), Tian X (2015), Hauri S (2016)	9
SKP2	2	PHB	0	affinity chromatography technology	Chander H (2010)	1
CCNA2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GPS1	1	RBX1	2	affinity chromatography technology	Lyapina S (2001)	1
SMAD4	9	STUB1	4	pull down, affinity chromatography technology	Li L (2004), Li L (2004)	2
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
SKP2	2	STK3	1	affinity chromatography technology	Huttlin EL (2017)	1
STK3	1	CDK3	0	affinity chromatography technology	Varjosalo M (2013)	1
BRCA1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2003), Maor S (2007), Maor S (2007), Abramovitch S (2003)	4
RBX1	2	DCUN1D3	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meyer-Schaller N (2009), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	4
STIL	3	OFD1	3	bioid	Gupta GD (2015)	1
RASSF1	3	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	PRKAR1B	5	affinity chromatography technology	Choudhury NR (2017)	1
TAL1	0	STUB1	4	affinity chromatography technology, affinity chromatography technology	Nie L (2008), Terme JM (2009)	2
CDK2	0	SF3B3	4	affinity chromatography technology	Neganova I (2011)	1
MYC	2	STUB1	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Paul I (2012), Paul I (2012), Paul I (2012), Huang H (2017)	4
BTRC	1	STK3	1	affinity chromatography technology, bioid, affinity chromatography technology	Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	3
UFD1	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Chen M (2011), Chen M (2011)	2
BARD1	4	CCDC88A	3	affinity chromatography technology	Woods NT (2012)	1
RASSF1	3	CUL1	7	affinity chromatography technology	Song MS (2008)	1
SIRT4	0	SIRT3	1	affinity chromatography technology	Ahuja N (2007)	1
ELAVL1	0	RRM2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
BTRC	1	PHLPP1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2009), Li X (2009), Gao G (2013)	3
COPS5	0	LRCH2	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
SIRT6	2	DDB1	6	affinity chromatography technology	Simeoni F (2013)	1
STIL	3	BTRC	1	bioid	Gupta GD (2015)	1
TRIM25	5	PPP1CA	3	affinity chromatography technology	Choudhury NR (2017)	1
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
DCUN1D3	1	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	8
TWIST1	0	SKP2	2	affinity chromatography technology	Ruan D (2017)	1
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
CCNE1	1	MRE11	3	affinity chromatography technology	Stewart GS (2003)	1
SKP2	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), Zhang Q (2013), Kim TA (2013), Jamal A (2015), Fujii M (2006)	9
COPS5	0	FAM83H	6	affinity chromatography technology	Bennett EJ (2010)	1
CKS1B	0	HSP90AA1	7	pull down	Radulovic M (2010)	1
NXF1	0	STUB1	4	affinity chromatography technology	Castello A (2012)	1
CCNA2	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Amador V (2007), Horton LE (1997), Lin ML (2011), Lin ML (2011), OConnor PM (1993), Varjosalo M (2013), Kikuchi R (2014), Mateo F (2009), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	13
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
CDK2	0	PSMD9	0	affinity chromatography technology	Park WH (2003)	1
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
LATS2	1	ANAPC1	1	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Zhu C (2018), Zhu C (2018), Zhu C (2018), Zhu C (2018)	6
MEF2C	16	SP1	0	two hybrid, affinity chromatography technology	Krainc D (1998), Krainc D (1998)	2
TRIM25	5	MTOR	14	affinity chromatography technology	Choudhury NR (2017)	1
AURKB	2	RB1	2	pull down, enzymatic study, affinity chromatography technology	Nair JS (2009), Nair JS (2009), Nair JS (2009)	3
LATS2	1	OFD1	3	bioid	Couzens AL (2013)	1
COPS6	0	CDKN1B	1	affinity chromatography technology	Choi HH (2015)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
ESR1	0	RUVBL1	2	affinity chromatography technology	Tarallo R (2011)	1
EP300	36	RUNX2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee HW (2006), Jeon EJ (2006), Jeon EJ (2006), Jun JH (2010)	4
RBX1	2	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
FZR1	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Liu W (2011), Liu W (2011)	2
CCNA2	1	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TAL1	0	TCF3	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Goardon N (2006), Goardon N (2006), Goardon N (2006), Goardon N (2006), Hsu HL (1994), Hsu HL (1994), Hu X (2009)	7
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
MYC	2	FOXO3	1	affinity chromatography technology	Chandramohan V (2008)	1
GMNN	0	CEP192	5	affinity chromatography technology	Huttlin EL (2017)	1
CUL2	3	E2F1	0	affinity chromatography technology, pull down	Xu J (2016), Xu J (2016)	2
SP1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singh J (2002), Chang YC (2001), Opitz OG (2000)	3
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
ELAVL1	0	CDKN1B	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL5	1	CUL1	7	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Huttlin EL (2015), Huttlin EL (2017)	3
BRCA1	7	CCNB1	3	pull down, affinity chromatography technology, enzymatic study	Wang H (1997), Shabbeer S (2013), Shabbeer S (2013)	3
STUB1	4	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, enzymatic study, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Zhang L (2007), Zhang M (2005), Tateishi Y (2004), Tateishi Y (2004), Connell P (2001), Ko HS (2009), Kumar P (2007), Kumar P (2007), Wang L (2011), Stankiewicz M (2010), Graf C (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Kundrat L (2010), Morishima Y (2008), Zhou P (2003), Zhang M (2008), Grelle G (2006), Kim SA (2005), Arndt V (2005), Muller P (2012), Burch L (2004), Burch L (2004), Jang KW (2011), Schuelke JP (2010), Wang Q (2012), Shimamoto S (2013), Shimamoto S (2013), Shimamoto S (2013), Gano JJ (2010), Skarra DV (2011), Yang SW (2013), Grelle G (2006), Grelle G (2006), Narayan V (2015)	36
CDK2	0	BARD1	4	enzymatic study	Hayami R (2005)	1
RUNX2	2	SKP2	2	affinity chromatography technology	Thacker G (2016)	1
BTRC	1	BTG2	0	affinity chromatography technology	Sasajima H (2012)	1
BTRC	1	BTG1	1	affinity chromatography technology	Sasajima H (2012)	1
PPP1CA	3	RUVBL1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Huttlin EL (2015), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	4
SKP2	2	CDC34	3	pull down, enzymatic study, pull down	Cen B (2010), Umanskaya K (2007), Ji P (2006)	3
TRIM25	5	UBE2L3	1	affinity chromatography technology	Choudhury NR (2017)	1
COPS6	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CUL1	7	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Dias DC (2002), Kim J (2002), Zheng N (2002), Kim AY (2008), Ohta T (1999), Ohta T (1999), Ohta T (1999), Bloom J (2006), Block K (2005), Hu J (2004), Hwang JW (2003), Furukawa M (2002), Kawakami T (2001), Ohta T (2001), Chen A (2000), Read MA (2000), Wu K (2000), Tan P (1999), Banerjee S (2010), Gao D (2010), Tron AE (2012), Tron AE (2012), Shteingart S (2012), Tan M (2010), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Huang DT (2004), Emberley ED (2012), Gastaldello S (2012), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Li X (2003), Calabrese MF (2011), Scott DC (2014), Scott DC (2014), Siergiejuk E (2009), Zhou W (2014), Zhou W (2014), Huang DT (2009), Pick E (2007), Morimoto M (2003), Morimoto M (2003), Ohki Y (2009), Duda DM (2008), Duda DM (2008), Wan C (2015), Hao J (2015), Hao J (2015), Han XR (2016), Kuang P (2016), Zhou W (2017), Hu Y (2017), Reitsma JM (2017)	59
ELAVL1	0	ING3	3	affinity chromatography technology	Abdelmohsen K (2009)	1
COPS7A	0	BTRC	1	affinity chromatography technology	Huang X (2016)	1
COPS5	0	VHL	0	affinity chromatography technology	Bemis L (2004)	1
CDT1	2	CCNE1	1	affinity chromatography technology	Liu E (2004)	1
CDC34	3	FBXW2	0	enzymatic study	Cenciarelli C (1999)	1
STUB1	4	FOXO1	2	affinity chromatography technology	Li F (2009)	1
FBXW8	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Okabe H (2007), Litterman N (2011), Busino L (2012), Watanabe N (2004), Ponyeam W (2012), Tian X (2015), Xu X (2008), Hauri S (2016)	9
HSP90AA1	7	PRKD2	3	affinity chromatography technology	Taipale M (2012)	1
ATM	9	BRCA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Gatei M (2000), Gatei M (2000), Kim ST (1999), Cortez D (1999), Cortez D (1999), Tibbetts RS (2000), Wang Y (2000), Mu JJ (2007), Tsai WB (2008), Gatei M (2000), Gatei M (2000), Gatei M (2000)	12
MTOR	14	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Geng Q (2017), Geng Q (2017), Geng Q (2017)	3
CUL4A	2	CDT1	2	affinity chromatography technology, affinity chromatography technology, biochemical	Hu J (2004), Higa LA (2003), He YJ (2006)	3
ELAVL1	0	SKP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
EP300	36	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kimbrel EA (2009), Kimbrel EA (2009)	2
BRCA1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Woods NT (2012), Woods NT (2012)	3
TRIM25	5	SAMHD1	3	affinity chromatography technology	Choudhury NR (2017)	1
BRCA1	7	CUL2	3	affinity chromatography technology	Ertych N (2016)	1
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
MYC	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	STK3	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Guo C (2007), Guo C (2007), Liu L (2007), Matallanas D (2007), Romano D (2010), Romano D (2010), Couzens AL (2013), Varjosalo M (2013), Fenton SL (2004), Huttlin EL (2015), Hauri S (2013), Hauri S (2013), Huttlin EL (2017), Ivanov AA (2017)	14
AKT1	1	GFAP	0	two hybrid	Arroyo R (2015)	1
SKP2	2	BARD1	4	affinity chromatography technology	Lu Y (2012)	1
CDKN1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology	Starostina NG (2010), Starostina NG (2010)	2
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
OFD1	3	KIAA1671	0	bioid	Gupta GD (2015)	1
OFD1	3	CCNA2	1	bioid	Gupta GD (2015)	1
SIRT6	2	IMPDH2	3	affinity chromatography technology	Simeoni F (2013)	1
ING3	3	CUL1	7	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
COPS5	0	RUVBL1	2	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	OFD1	3	bioid	Coyaud E (2015)	1
TRPC4AP	4	RBX1	2	affinity chromatography technology	Choi SH (2010)	1
CDK2	0	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK3	0	CDT1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SKP2	2	KPNA6	1	affinity chromatography technology, affinity chromatography technology, unspecified method	Gao D (2009), Inuzuka H (2012), Inuzuka H (2012)	3
ELAVL1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology	Chu PC (2012), Chu PC (2012)	2
BARD1	4	RAD50	3	biochemical, affinity chromatography technology	Greenberg RA (2006), Greenberg RA (2006)	2
SKP2	2	GFAP	0	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	BRAP	0	affinity chromatography technology	Asada M (2004)	1
CUL1	7	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
EP300	36	DDB1	6	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
DDB1	6	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
CDK2	0	ESR1	0	enzymatic study, affinity chromatography technology	Zhou W (2014), Zhou W (2014)	2
ELAVL1	0	NLK	1	affinity chromatography technology	Abdelmohsen K (2009)	1
TRIM25	5	WEE1	2	affinity chromatography technology	Choudhury NR (2017)	1
HSP90AA1	7	CDKN1B	1	genetic interference	Srivas R (2016)	1
RND3	0	SKP2	2	affinity chromatography technology, pull down, enzymatic study	Lonjedo M (2013), Lonjedo M (2013), Lonjedo M (2013)	3
CUL1	7	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
SIRT6	2	STUB1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ronnebaum SM (2013), Ronnebaum SM (2013), Ronnebaum SM (2013)	3
COPS6	0	FBXL18	5	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	YWHAB	1	affinity chromatography technology	Abdelmohsen K (2009)	1
AKT1	1	CDKN1B	1	enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology	Fujita N (2002), Fujita N (2002), Nacusi LP (2006), Chen TC (2014), Zhang H (2017), Zhang H (2017)	6
STIL	3	CUL1	7	bioid	Gupta GD (2015)	1
BTRC	1	SP1	0	pull down	Wei S (2009)	1
TAL1	0	CDK9	3	affinity chromatography technology, affinity chromatography technology	Bai X (2010), Bai X (2010)	2
PPP1CA	3	CDH1	4	affinity chromatography technology, bioid	Flores-Delgado G (2007), Guo Z (2014)	2
SMAD7	1	AKT1	1	affinity chromatography technology	Song K (2006)	1
MYC	2	WEE1	2	genetic interference	Toyoshima M (2012)	1
EP300	36	COPS6	0	two hybrid	Stelzl U (2005)	1
DDB1	6	GPS1	1	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Jin J (2006), Emberley ED (2012), Cavadini S (2016)	3
OFD1	3	AURKB	2	bioid	Gupta GD (2015)	1
FOXO1	2	SIRT2	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Daitoku H (2004), Daitoku H (2004), Daitoku H (2004), Zhao Y (2010), Pramanik KC (2014)	5
MYC	2	UBE2L3	1	affinity chromatography technology	Shimura H (2001)	1
ATM	9	FOXO1	2	imaging technique	Ochodnicka-Mackovicova K (2016)	1
PSMD9	0	SKP2	2	fluorescent resonance energy transfe	Xu S (2007)	1
RBL2	5	CCNA1	3	pull down	Yang R (1999)	1
DDB1	6	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Jamal A (2015), Huttlin EL (2017)	4
AR	3	PPP1CA	3	affinity chromatography technology, affinity chromatography technology	Liu X (2016), Liu X (2016)	2
RB1	2	CDKN1C	0	pull down	Nakanishi M (1999)	1
SIRT3	1	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Iwahara T (2012), Iwahara T (2012), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012)	5
FZR1	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SP1	0	MYCN	2	affinity chromatography technology, pull down	Iraci N (2011), Iraci N (2011)	2
AKT1	1	STUB1	4	affinity chromatography technology, affinity chromatography technology	Dickey CA (2008), Su CH (2011)	2
NDRG1	2	MYC	2	affinity chromatography technology, affinity chromatography technology	Wang Y (2017), Wang Y (2017)	2
TRIM25	5	FZR1	1	affinity chromatography technology	Choudhury NR (2017)	1
CCNA2	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Amador V (2007), Wu G (1997), Lin ML (2011), Chen J (1996), Levkau B (1998), Poon RY (1996), Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
NBN	1	RAD50	3	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Desai-Mehta A (2001), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Greenberg RA (2006), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015)	17
MYC	2	CDK9	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kanazawa S (2003), Bres V (2009), Eberhardy SR (2001), Gargano B (2007), Jaenicke LA (2016)	5
SKP2	2	DPYSL4	0	affinity chromatography technology	Huttlin EL (2017)	1
BTRC	1	SMAD4	9	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wan M (2004), Wan M (2004), Yang L (2006), Yang L (2006), Wan M (2005), Liang M (2004), Demagny H (2014), Li D (2015)	8
ELAVL1	0	ATM	9	affinity chromatography technology	Abdelmohsen K (2009)	1
GMNN	0	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
YWHAB	1	CDKN1B	1	pull down	Sekimoto T (2004)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
BARD1	4	NBN	1	biochemical, affinity chromatography technology	Greenberg RA (2006), Greenberg RA (2006)	2
RNF7	0	VHL	0	affinity chromatography technology	Tan M (2008)	1
DCUN1D3	1	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
BRCA1	7	RBL2	5	imaging technique, pull down	Fan S (2001), Fan S (2001)	2
VHL	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Kohroki J (2005), Kamura T (2002), Kuznetsova AV (2003), Norman JA (2006), Knauth K (2006), Kamura T (2004), Heir P (2013), Essers PB (2014), Lee SB (2016)	10
SKP2	2	MYBL2	2	affinity chromatography technology	Charrasse S (2000)	1
RASSF1	3	SKP1	0	affinity chromatography technology	Song MS (2008)	1
VHL	0	SP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Yuen JS (2007), Mukhopadhyay D (1997), Mukhopadhyay D (1997)	3
TP73	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Katayama H (2012), Katayama H (2012)	2
RASSF1	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Jiang L (2011), Jiang L (2011)	2
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
UBE2L3	1	SMAD7	1	unspecified method	Ogunjimi AA (2005)	1
CUL1	7	FZR1	1	affinity chromatography technology, affinity chromatography technology	Fukushima H (2013), Fukushima H (2013)	2
CKS1B	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	FBXW8	2	affinity chromatography technology	He YJ (2006)	1
JAK2	1	CDKN1B	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Jaekel H (2011), Jaekel H (2011), Jaekel H (2011)	3
CUL2	3	NDRG1	2	affinity chromatography technology	Ambrosini G (2009)	1
MYC	2	CUL4A	2	affinity chromatography technology	Choi SH (2010)	1
VHL	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Kamura T (2001), Hacker KE (2008), Hacker KE (2008), Menon S (2008), Chew EH (2007), Ietta F (2006), Megumi Y (2005), Kamura T (2002), Kuznetsova AV (2003), Hansen WJ (2002), Cockman ME (2000), Lisztwan J (1999), Lisztwan J (1999), Sufan RI (2006), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Knauth K (2006), Lonergan KM (1998), Lai Y (2012), Miller F (2005), Mahrour N (2008), Grosfeld A (2007), Russell RC (2011), Foxler DE (2012), Bonicalzi ME (2001), Bennett EJ (2010), Kanaya K (2002), Liakopoulos D (1999), Pause A (1997), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Pause A (1999), Pause A (1999), Xin H (2011), Kamura T (2004), Kamura T (2004), Heir P (2013), Russell RC (2008), Russell RC (2008), Essers PB (2014), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Heir P (2016), Chen K (2016), Uematsu K (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	54
COPS2	5	ANAPC1	1	affinity chromatography technology, affinity chromatography technology	Kob R (2009), Kob R (2009)	2
IMPDH1	2	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
ELAVL1	0	DCUN1D3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CCNA2	1	CDKN1B	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Schulman BA (1998), Datta NS (1998), Vlach J (1997), Levkau B (1998), Grimmler M (2007), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CDC34	3	PIM1	2	affinity chromatography technology	Cen B (2010)	1
COPS5	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Guo H (2016), Guo H (2016)	2
CDH1	4	SLC9A3R1	2	bioid	Guo Z (2014)	1
ELAVL1	0	SENP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FZR1	1	CCNA1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sorensen CS (2001), Sorensen CS (2001), Gao D (2009), Fukushima H (2013)	4
SKP2	2	CDH1	4	affinity chromatography technology, enzymatic study	Chen JY (2011), Liu YQ (2015)	2
SUGT1	1	SKP1	0	pull down, pull down, pull down, affinity chromatography technology, biochemical	Nowotny M (2003), Zhang M (2008), Zhang M (2008), Niikura Y (2006), Wan C (2015)	5
NXF1	0	BTRC	1	affinity chromatography technology	Castello A (2012)	1
CDC20	1	RASSF1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chow C (2011), Chow C (2011), Wang X (2008), Song MS (2004)	4
COPS5	0	SKIV2L2	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	IMPDH2	3	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Varjosalo M (2013)	2
PPP1CA	3	BRCA1	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Winter SL (2007), Liu Y (2002), Liu Y (2002), Liu Y (2002), Liu Y (2002), Woods NT (2012), Chen BY (2014)	7
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
CDK2	0	PHB	0	affinity chromatography technology	Neganova I (2011)	1
FOXO3	1	BRCA1	7	affinity chromatography technology	Tsai WB (2008)	1
COPS5	0	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	KPNA1	5	affinity chromatography technology	Bennett EJ (2010)	1
CDT1	2	CDC20	1	pull down	Sugimoto N (2008)	1
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
CUL4A	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Bennett EJ (2010), Taipale M (2012)	3
DCUN1D3	1	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
BRCA1	7	CDH1	4	genetic interference	Shen JP (2017)	1
SKP2	2	ALMS1	13	affinity chromatography technology	Huttlin EL (2017)	1
CKS1B	0	SKP1	0	pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology	Yao ZP (2006), Seeliger MA (2005), Radulovic M (2010), Ungermannova D (2013), Hauri S (2016)	5
CUL5	1	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	TUBB3	3	affinity chromatography technology	Abdelmohsen K (2009)	1
RBX1	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, bioid	Tan M (2010), Oshikawa K (2003), Coyaud E (2015)	3
SKP2	2	YY1	7	pull down	Wan M (2012)	1
RB1	2	CDK9	3	pull down, affinity chromatography technology, enzymatic study, enzymatic study, biochemical, enzymatic study	Simone C (2002), Simone C (2002), De Luca A (1997), Garriga J (1996), Garriga J (1996), Grana X (1994)	6
SP1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Wang CH (2006), Fojas de Borja P (2001), Haidweger E (2001), Haidweger E (2001)	4
CCNB1	3	CDKN1B	1	affinity chromatography technology	Hein MY (2015)	1
CDKN1A	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Gao J (2015)	3
BARD1	4	MRE11	3	affinity chromatography technology	Greenberg RA (2006)	1
ELAVL1	0	PSMD9	0	affinity chromatography technology	Abdelmohsen K (2009)	1
PPP1CA	3	SKP2	2	affinity chromatography technology	Liu X (2016)	1
FBXW2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Saiga T (2009), Xu J (2017)	2
HSP90AA1	7	TTC9C	2	affinity chromatography technology	Gano JJ (2010)	1
CCNG2	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Xu G (2008), Xu G (2008)	2
CUL1	7	CKS1B	0	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Radulovic M (2010), Huttlin EL (2017)	3
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
TRIM25	5	ESR1	0	affinity chromatography technology, pull down, enzymatic study	Nakajima A (2007), Nakajima A (2007), Nakajima A (2007)	3
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
CDKN1C	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Kamura T (2003), Calvisi DF (2009), Kamura T (2003)	3
PHLPP1	4	STUB1	4	affinity chromatography technology	Gangula NR (2013)	1
LATS2	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
COPS5	0	TRPC4AP	4	affinity chromatography technology	Bennett EJ (2010)	1
SP1	0	SMAD4	9	affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Luciakova K (2008), Pardali K (2000), Pardali K (2000), Pardali K (2000), Chung CL (2011), Jungert K (2006)	6
SKP2	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
OFD1	3	MRE11	3	affinity chromatography technology	Gupta GD (2015)	1
SKP2	2	PRKD2	3	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	TUBB3	3	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	UBE2L3	1	affinity chromatography technology	Ma X (2017)	1
SKP2	2	USP13	2	affinity chromatography technology	Chen M (2011)	1
CDK2	0	SPDYA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Porter LA (2003), McAndrew CW (2007), Gastwirt RF (2006), Dinarina A (2009), Porter LA (2002), Porter LA (2002), Barnes EA (2003)	7
CDK1	0	E2F1	0	enzymatic study	Dynlacht BD (1997)	1
CEBPA	0	AR	3	pull down	Boruk M (1998)	1
PIM1	2	CDKN1A	1	enzymatic study, pull down	Wang Z (2002), Wang Z (2002)	2
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
ASB2	1	TCF3	7	affinity chromatography technology	Nie L (2011)	1
RASSF1	3	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ATM	9	CDK9	3	imaging technique	Fang L (2014)	1
PIM1	2	FZR1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Cen B (2010), Cen B (2010)	3
ELAVL1	0	SKP2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
TRIM25	5	YWHAB	1	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	TTC9C	2	affinity chromatography technology	Huttlin EL (2017)	1
KMT2A	58	CDK9	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2010), Monroe SC (2011), Tan J (2011)	3
CCNE1	1	CDK1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Koff A (1992), Koff A (1992), Horton LE (1997)	4
EP300	36	SMAD7	1	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Groenroos E (2002), Groenroos E (2002), Groenroos E (2002), Groenroos E (2002)	4
CUL5	1	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
RBL2	5	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
SKP2	2	ORC1	3	pull down, affinity chromatography technology	Mendez J (2002), Mendez J (2002)	2
SKP2	2	STIL	3	affinity chromatography technology	Huttlin EL (2017)	1
ATM	9	VHL	0	affinity chromatography technology, genetic interference	Roe JS (2006), Shen JP (2017)	2
CUL2	3	SF3B3	4	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Cordero-Espinoza L (2013)	2
CUL1	7	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
JAK2	1	HSP90AA1	7	affinity chromatography technology	Cheng MB (2010)	1
CDKN1B	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miranda-Carboni GA (2008), Bondar T (2006), Li B (2006), Li B (2006), Gao J (2015)	5
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
VHL	0	CDC34	3	pull down	Masson N (2001)	1
CDK9	3	SMAD4	9	genetic interference	Shen JP (2017)	1
TRIM25	5	FBXL18	5	affinity chromatography technology	Choudhury NR (2017)	1
COPS6	0	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	YWHAB	1	affinity chromatography technology	Koch HB (2007)	1
CKS1B	0	137529	0	pull down	Seeliger MA (2005)	1
BRCA1	7	CCNE1	1	affinity chromatography technology	Matsuoka S (2007)	1
CDK1	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FBXW2	0	BTG2	0	affinity chromatography technology	Sasajima H (2012)	1
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
COPS6	0	CCNA1	3	affinity chromatography technology	Bennett EJ (2010)	1
RUNX2	2	RB1	2	affinity chromatography technology	Thomas DM (2004)	1
TRIM25	5	CUL5	1	affinity chromatography technology	Choudhury NR (2017)	1
CDC34	3	CUL1	7	pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology	Block K (2005), Wirbelauer C (2000), Saha A (2008), Sandoval D (2014), Wu K (2016)	5
SKP2	2	DISC1	6	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	CDK9	3	two hybrid	Woods NT (2012)	1
BRCA1	7	RUVBL1	2	affinity chromatography technology	Ertych N (2016)	1
YY1	7	RUVBL1	2	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu S (2007), Wu S (2007), Wu S (2007), Cai Y (2007), Cai Y (2007), Huttlin EL (2017), Hauri S (2016)	7
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
PHB	0	AR	3	affinity chromatography technology	Gamble SC (2007)	1
CCNA1	3	SKP2	2	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji P (2006), Ji P (2006), Ji P (2006), Yam CH (2000), Gao D (2009), Ji P (2007)	6
VHL	0	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology	Ji W (2014), Ji W (2014), Ji W (2014)	3
SAMHD1	3	DDB1	6	affinity chromatography technology	Ahn J (2012)	1
CUL2	3	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
MRE11	3	RAD50	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Chiba N (2001), Chiba N (2001), Dolganov GM (1996), Dolganov GM (1996), Trujillo KM (1998), Goedecke W (1999), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Cho YW (2007), Greenberg RA (2006), Alt JR (2005), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Wijnhoven P (2015), Boldt K (2016), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015), Nicholson J (2017)	25
SKP2	2	KPNA1	5	affinity chromatography technology, affinity chromatography technology, unspecified method	Gao D (2009), Inuzuka H (2012), Inuzuka H (2012)	3
E2F1	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Budhavarapu VN (2012), Budhavarapu VN (2012), Budhavarapu VN (2012), Singh RK (2017)	4
CDKN1B	1	VHL	0	genetic interference	Shen JP (2017)	1
CDK2	0	SP1	0	enzymatic study	Fojas de Borja P (2001)	1
BRCA1	7	E2F1	0	affinity chromatography technology	Gorski JJ (2011)	1
BTG2	0	SKP1	0	affinity chromatography technology	Sasajima H (2012)	1
WEE1	2	MTOR	14	genetic interference	Srivas R (2016)	1
TRIM25	5	CDK1	0	affinity chromatography technology	Choudhury NR (2017)	1
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
RBX1	2	RNF126	2	two hybrid	Woodsmith J (2012)	1
MYC	2	CDK2	0	genetic interference, genetic interference	Toyoshima M (2012), Zhou Z (2014)	2
SIRT6	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Thirumurthi U (2014), Thirumurthi U (2014), Thirumurthi U (2014)	3
BTRC	1	ALMS1	13	bioid	Coyaud E (2015)	1
AKT1	1	FOXO3	1	enzymatic study, imaging technique	Sundaresan NR (2011), Chen TC (2014)	2
MYBL2	2	CDKN1C	0	pull down, affinity chromatography technology	Joaquin M (2003), Joaquin M (2003)	2
MEF2D	5	COPS5	0	two hybrid	Bandyopadhyay S (2010)	1
TRIM49	6	SKP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ING3	3	RBX1	2	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
CDH1	4	E2F1	0	affinity chromatography technology	Peart MJ (2010)	1
USP19	1	STUB1	4	affinity chromatography technology	He WT (2016)	1
EP300	36	RAD50	3	affinity chromatography technology, pull down	Jung SY (2005), Karmakar S (2010)	2
EP300	36	CDT1	2	enzymatic study	Glozak MA (2009)	1
YWHAB	1	SLC9A3R1	2	biochemical	Kristensen AR (2012)	1
SKP2	2	PRKAR1B	5	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	ANAPC1	1	affinity chromatography technology	Choudhury NR (2017)	1
FOXO1	2	RB1	2	affinity chromatography technology	Li X (2015)	1
BTRC	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	4
FBXW8	2	CUL2	3	affinity chromatography technology	Litterman N (2011)	1
MYBL2	2	CDK9	3	genetic interference, pull down, affinity chromatography technology, enzymatic study	De Falco G (2000), De Falco G (2000), De Falco G (2000), De Falco G (2000)	4
CUL1	7	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Min KW (2005), Min KW (2005), Yang X (2002), Yang X (2002), Huang X (2005), Bennett EJ (2010), Scherer PC (2016), Scherer PC (2016), Reitsma JM (2017)	9
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
FBXW8	2	FBXW2	0	affinity chromatography technology	Ponyeam W (2012)	1
TRIM25	5	TUBB3	3	affinity chromatography technology	Choudhury NR (2017)	1
SKP1	0	CDKN1A	1	imaging technique	Chen TC (2014)	1
BRCA1	7	SKP1	0	affinity chromatography technology, affinity chromatography technology	Lu Y (2012), Lu Y (2012)	2
COPS5	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
BRCA1	7	TRIM25	5	affinity chromatography technology	Ertych N (2016)	1
RNF7	0	ELOC	0	pull down, pull down	Kim DY (2013), Kershaw NJ (2014)	2
FBXW2	0	BTG1	1	affinity chromatography technology	Sasajima H (2012)	1
CCNA1	3	CDK1	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sweeney C (1996), Lukas J (1992), Desai D (1995), Rohaly G (2005)	4
MTOR	14	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Alayev A (2016), Alayev A (2016), Alayev A (2016)	3
CDC20	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Amador V (2007), Fogeron ML (2013)	2
ELAVL1	0	TOB1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
RBX1	2	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Gao D (2010), Gao D (2010)	2
CEP192	5	OFD1	3	bioid, bioid	Firat-Karalar EN (2014), Gupta GD (2015)	2
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
HSP90AA1	7	SKIV2L2	0	affinity chromatography technology	Hein MY (2015)	1
MTOR	14	SMAD4	9	genetic interference	Shen JP (2017)	1
NXF1	0	CUL2	3	affinity chromatography technology	Castello A (2012)	1
SAMHD1	3	CUL4A	2	affinity chromatography technology	Morrissey C (2015)	1
YY1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bennett MK (1999), Li H (2008), Li H (2008), Santiago FS (2007), Qiao H (2011), Lee JS (1993), Lee JS (1993)	7
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
CDK2	0	TP73	2	enzymatic study	Gaiddon C (2003)	1
STK3	1	AURKB	2	affinity chromatography technology	Couzens AL (2013)	1
CDKN1B	1	DDB1	6	affinity chromatography technology	Iovine B (2011)	1
ELAVL1	0	BARD1	4	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXW8	2	SKP2	2	affinity chromatography technology	Ponyeam W (2012)	1
TRIM25	5	COPS2	5	affinity chromatography technology	Choudhury NR (2017)	1
E2F1	0	ESR1	0	affinity chromatography technology, affinity chromatography technology	Liu W (2012), Liu W (2012)	2
BTRC	1	KANK2	4	bioid	Coyaud E (2015)	1
CDKN1A	1	COPS6	0	two hybrid	Vinayagam A (2011)	1
CCNB1	3	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	3
CCNE1	1	RBL2	5	affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Li Y (1993)	2
YY1	7	TCF3	7	affinity chromatography technology	Cai Y (2007)	1
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
COPS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009)	5
SPDYA	1	CDKN1B	1	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Porter LA (2003), Porter LA (2003), Porter LA (2003), McAndrew CW (2007)	4
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
AR	3	KMT2A	58	affinity chromatography technology, affinity chromatography technology	Grasso CS (2012), Grasso CS (2012)	2
SKP2	2	LRCH2	0	affinity chromatography technology	Huttlin EL (2017)	1
ELAVL1	0	MYC	2	affinity chromatography technology	Abdelmohsen K (2009)	1
CDK9	3	SKP1	0	pull down, affinity chromatography technology	Kiernan RE (2001), Kiernan RE (2001)	2
SKP2	2	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CUL5	1	LRRC58	0	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	USP19	1	affinity chromatography technology	Choudhury NR (2017)	1
OFD1	3	IMPDH2	3	affinity chromatography technology	Gupta GD (2015)	1
MTOR	14	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007)	59
E2F1	0	DDB1	6	affinity chromatography technology	Hayes S (1998)	1
VHL	0	CDK2	0	affinity chromatography technology	Ewing RM (2007)	1
MYC	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Koch HB (2007), von der Lehr N (2003), Wang J (2011)	3
RNF126	2	E2F1	0	affinity chromatography technology, pull down, pull down	Wang Y (2016), Wang Y (2016), Wang Y (2016)	3
SKP2	2	MRE11	3	affinity chromatography technology	Wu J (2012)	1
KDM5C	9	MTOR	14	genetic interference	Shen JP (2017)	1
MYC	2	BTRC	1	affinity chromatography technology, enzymatic study	Popov N (2010), Popov N (2010)	2
CUL2	3	ELOC	0	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kamura T (2001), Maine GN (2007), Megumi Y (2005), Mao X (2009), Lonergan KM (1998), Lonergan KM (1998), Bennett EJ (2010), Pause A (1997), Pause A (1999), Kamura T (2004), Kelsall IR (2013), Lee SB (2016)	12
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
NLK	1	CUL1	7	affinity chromatography technology	Kanei-Ishii C (2008)	1
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
SIRT6	2	SENP1	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
RB1	2	MYC	2	two hybrid, fluorescent resonance energy transfe	Adnane J (1995), Ivanov AA (2017)	2
SAMHD1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014)	2
ESR1	0	PPP1CA	3	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
RNF7	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Tan M (2010), Kuang P (2016), Kuang P (2016), Kuang P (2016)	4
BARD1	4	CDK9	3	affinity chromatography technology	Woods NT (2012)	1
CDKN1B	1	MYC	2	affinity chromatography technology, protein complementation assay	Bahram F (2016), Bahram F (2016)	2
NLK	1	FOXO1	2	affinity chromatography technology	Szypowska AA (2011)	1
SKP2	2	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Roe JS (2011), Roe JS (2011), Roe JS (2011)	3
TRIM49	6	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EP300	36	MYBL2	2	affinity chromatography technology, enzymatic study	Johnson LR (2002), Johnson LR (2002)	2
CUL5	1	VHL	0	pull down	Kamura T (2001)	1
FBXW2	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Xu J (2017), Xu J (2017), Xu J (2017)	3
STUB1	4	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Biswas K (2017), Biswas K (2017), Biswas K (2017)	3
TRIM25	5	CCDC88A	3	affinity chromatography technology	Choudhury NR (2017)	1
RICTOR	4	AKT1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study	Sarbassov DD (2006), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Woods NT (2012), Kim EK (2011), Chen CH (2011), Garcia-Martinez JM (2009), Chen TC (2014), Pitre A (2012)	10
CDK9	3	RUVBL1	2	affinity chromatography technology	Jeronimo C (2007)	1
CDK3	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
TRIM25	5	SPDYA	1	affinity chromatography technology	Choudhury NR (2017)	1
COPS5	0	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
NLK	1	FOXO3	1	affinity chromatography technology	Szypowska AA (2011)	1
MYC	2	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology	Choi SH (2010), Jamal A (2015)	2
CUL1	7	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015)	2
HSP90AA1	7	AR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016)	11
DDB1	6	ESR1	0	affinity chromatography technology	Ohtake F (2007)	1
E2F1	0	CDK2	0	pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu M (1994), Dynlacht BD (1997), Dynlacht BD (1997), Ohta T (2001)	4
SKP2	2	TCF3	7	affinity chromatography technology, affinity chromatography technology	Nie L (2003), Huang Z (2004)	2
CDKN1A	1	TUBB3	3	two hybrid	Vinayagam A (2011)	1
ING3	3	DNAJB5	4	affinity chromatography technology	Hein MY (2015)	1
ASB2	1	JAK2	1	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
BRCA1	7	TUBB3	3	affinity chromatography technology	Ertych N (2016)	1
CKS1B	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jackman M (2002), Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CDC14B	1	AURKB	2	bioid	St-Denis N (2016)	1
NBN	1	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
CCNA2	1	137529	0	affinity chromatography technology	Mateo F (2009)	1
DDB1	6	BTRC	1	affinity chromatography technology	He YJ (2006)	1
SKP2	2	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
CDC34	3	CDKN1B	1	enzymatic study, unspecified method	Ryu KS (2008), Duda DM (2012)	2
TRIM21	0	UBE2L3	1	pull down	Wada K (2006)	1
AR	3	FOXO1	2	affinity chromatography technology, two hybrid, far western blotting	Li P (2003), Li P (2003), Li P (2003)	3
WEE1	2	FZR1	1	genetic interference	Srivas R (2016)	1
CEBPA	0	ESR1	0	pull down	Boruk M (1998)	1
RUVBL1	2	ELAVL1	0	affinity chromatography technology	Jeronimo C (2007)	1
RBX1	2	CDC34	3	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Wu K (2002), Block K (2005), Block K (2005), Chen A (2000), Cen B (2010), Cen B (2009), DAngiolella V (2010), Spruck C (2001), Shaik S (2012), Kruiswijk F (2012), Tan M (2010), Bashir T (2010), Higa LA (2003), Kanayama A (2004), Lan L (2012), Welcker M (2011), Banks D (2006), Kumar KG (2003), Higa LA (2006), Saha A (2008), Jin J (2005), Cen B (2009), Tedesco D (2002), Choi YS (2010), Duan S (2011), Li X (2003), Wang W (2003), Gallegos JR (2008), Peschiaroli A (2009), Banerjee S (2010), Duan S (2011), Wang F (2011), Chen H (2013), Rodier G (2008), Rossi M (2013), Ungermannova D (2013), Ooi LC (2013), Ziemba A (2013), Huang H (2014), Herrero-Ruiz J (2014), Kim J (2014), Min SH (2012), Watanabe M (2011), Gao D (2010), Zhou W (2014), Canettieri G (2010), Morimoto M (2003), Chen A (2002), Pashkova N (2010), Read MA (2000), Bassermann F (2005), Duda DM (2008), Enchev RI (2012), Fukushima H (2013), Tintignac LA (2005), Ungermannova D (2005), Low TY (2014), Walter D (2016), Gao J (2015), Orthwein A (2015), Wu K (2016), Wu K (2016), Nateri AS (2004), Pierce NW (2009), Kim JH (2015), Shimizu K (2017), Gschweitl M (2016), Ibarra R (2016), Kuang P (2016), Kuang P (2016), Kuang P (2016), Ferretti LP (2016), Kuchay S (2017), Gazdoiu S (2007), Dai X (2017)	75
FBXW8	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Okabe H (2007), Xu X (2008)	3
CDKN1A	1	CEBPA	0	pull down, two hybrid	Timchenko NA (1997), Timchenko NA (1997)	2
ELOC	0	ASB2	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nie L (2011), Lievens S (2009), Bello NF (2009), Zakaria R (2013)	4
CUL1	7	AKT1	1	affinity chromatography technology	Reitsma JM (2017)	1
RNF126	2	SKP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM25	5	BTRC	1	affinity chromatography technology	Choudhury NR (2017)	1
COPS2	5	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Yang X (2002), Choo YY (2011), Bennett EJ (2010), Huttlin EL (2015), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	7
COPS6	0	IMPDH2	3	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	MTOR	14	affinity chromatography technology	Woods NT (2012)	1
CDK1	0	WEE1	2	enzymatic study	Watanabe N (2004)	1
CCNB1	3	RB1	2	enzymatic study, enzymatic study	Jiang W (1998), Knudsen ES (1997)	2
MEF2C	16	COPS5	0	two hybrid	Bandyopadhyay S (2010)	1
SKP2	2	RUVBL1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK9	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	5
CDT1	2	ORC1	3	pull down	Ramachandran N (2004)	1
TRIM25	5	RRM2	2	affinity chromatography technology	Choudhury NR (2017)	1
IMPDH1	2	IMPDH2	3	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
SKP1	0	FBXL18	5	affinity chromatography technology	Hauri S (2016)	1
OFD1	3	SUGT1	1	bioid	Gupta GD (2015)	1
CDT1	2	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Nishitani H (2004), Liu E (2004)	2
ASB2	1	CUL1	7	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
CDK2	0	SKP1	0	x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao ZP (2006), Lyapina SA (1998), Zhang H (1995), Varjosalo M (2013), So J (2015), Hein MY (2015)	6
CDK9	3	SKP2	2	affinity chromatography technology	Kiernan RE (2001)	1
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
CCNB1	3	FZR1	1	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Ke PY (2004), Huang NJ (2012), Pfleger CM (2001), Miller JJ (2006), Song MS (2011), Frye JJ (2013), Lau AW (2013), Brown NG (2014), Summers MK (2009), ODonovan KJ (2010), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Lu L (2013), Yamaguchi M (2015), Brown NG (2015), Chen TC (2014), Williamson A (2011), Qiao R (2016), Brown NG (2016), Huttlin EL (2017)	22
CDKN1B	1	SKP1	0	unspecified method, unspecified method	Carrano AC (1999), Ooi LC (2013)	2
ELAVL1	0	FAM83H	6	affinity chromatography technology	Abdelmohsen K (2009)	1
SMAD4	9	CEBPA	0	pull down	Choy L (2003)	1
RRM2	2	WEE1	2	genetic interference	Shen JP (2017)	1
CUL4A	2	SF3B3	4	affinity chromatography technology	Cordero-Espinoza L (2013)	1
SKP2	2	ELOC	0	affinity chromatography technology	Kimura Y (2007)	1
SMAD4	9	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down	Yang L (2006), Liang M (2004), Liang M (2004)	3
CUL2	3	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
SUGT1	1	LRRC40	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CDKN1A	1	SMAD4	9	imaging technique	Chen TC (2014)	1
ELAVL1	0	UBE2L3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
AR	3	STUB1	4	affinity chromatography technology, pull down, enzymatic study, unspecified method, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	DaSilva J (2009), Chymkowitch P (2011), Chymkowitch P (2011), Rees I (2006), He B (2004), He B (2004), Schuelke JP (2010), McClurg UL (2016), Wang J (2016), Wang J (2016), Wang J (2016)	11
PHLPP1	4	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mistafa O (2010), Gao T (2005), Gao T (2005), Zhang X (2016)	4
CHKA	1	SKP2	2	enzymatic study	Gao D (2009)	1
TRIM25	5	TRPC4AP	4	affinity chromatography technology	Choudhury NR (2017)	1
ASB2	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
CCNB1	3	FOXO1	2	imaging technique	Chen TC (2014)	1
AKT1	1	MTOR	14	pull down, unspecified method, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, imaging technique	Sekulic A (2000), Cheng SW (2004), Oh WJ (2010), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Martin J (2008), Facchinetti V (2008), Facchinetti V (2008), Chen CH (2011), Xu Y (2013), Glidden EJ (2012), Chen TC (2014), Pitre A (2012), Moon HE (2015)	15
CUL4A	2	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Hein MY (2015)	7
CUL2	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
PPP1CA	3	CCNA1	3	affinity chromatography technology	Flores-Delgado G (2007)	1
CUL1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Gao D (2010), Gao D (2010), Gao D (2010), Gao D (2010)	4
RNF7	0	CUL1	7	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ohta T (1999), Kawakami T (2001), Tan M (2010), Swaroop M (2001), Huang DT (2009), Kuang P (2016), Zhou W (2017)	7
SAMHD1	3	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014), Huttlin EL (2015), Huttlin EL (2017)	4
FBXW8	2	HSP90AA1	7	affinity chromatography technology	Ponyeam W (2012)	1
CCNA2	1	FZR1	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Jin L (2008), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Williamson A (2011), Huttlin EL (2017), Choudhury R (2016)	8
IFI27	2	SKP2	2	affinity chromatography technology, affinity chromatography technology	Xue B (2016), Xue B (2016)	2
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
ELAVL1	0	YY1	7	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
SKP2	2	ATM	9	affinity chromatography technology	Wu J (2012)	1
RNF126	2	RAD50	3	affinity chromatography technology	OConnor HF (2015)	1
NLK	1	MYBL2	2	affinity chromatography technology	Kurahashi T (2005)	1
SKP2	2	STUB1	4	affinity chromatography technology	Huang Z (2004)	1
BRCA1	7	TP73	2	affinity chromatography technology	Ibrahim N (2010)	1
CDC20	1	CCNB1	3	enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Garnett MJ (2009), ODonovan KJ (2010), Ke PY (2004), Braunstein I (2007), van Zon W (2010), van Zon W (2010), Pfleger CM (2001), Wolthuis R (2008), Kwan PS (2013), Tian W (2012), Han JS (2013), Lim HJ (2013), Han JS (2014), Brown NG (2014), Townsend K (2009), Sedgwick GG (2013), Lara-Gonzalez P (2011), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Wu T (2010), Uzunova K (2012), Shoji S (2014), Sedgwick GG (2013), Lara-Gonzalez P (2011), Diaz-Martinez LA (2015), Brown NG (2015), Lischetti T (2014), Tipton AR (2013), Lee SB (2015), Lee SB (2015), Jia L (2016)	33
OFD1	3	CDK2	0	bioid	Gupta GD (2015)	1
ELAVL1	0	RICTOR	4	affinity chromatography technology	Abdelmohsen K (2009)	1
HSP90AA1	7	FBXL18	5	affinity chromatography technology	Taipale M (2012)	1
SKP2	2	MEF2D	5	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Di Giorgio E (2015), Di Giorgio E (2015), Di Giorgio E (2015), Di Giorgio E (2015)	4
EP300	36	NBN	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Jung SY (2005), Jang ER (2011), Jang ER (2011)	3
BTG2	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Park TJ (2009), Park TJ (2009), Sasajima H (2012), Sasajima H (2012), Sasajima H (2012)	5
TRIM25	5	IMPDH2	3	affinity chromatography technology	Choudhury NR (2017)	1
AURKB	2	EP300	36	affinity chromatography technology	Fogeron ML (2013)	1
RNF126	2	SKIV2L2	0	affinity chromatography technology	OConnor HF (2015)	1
MYC	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RAD50	3	MCM8	3	affinity chromatography technology	Lee KY (2015)	1
SKP2	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhou W (2014), Zhou W (2014), Zhou W (2014)	3
TP73	2	CDT1	2	affinity chromatography technology	Lunardi A (2010)	1
CDH1	4	HSP90AA1	7	affinity chromatography technology	Catimel B (2005)	1
COPS6	0	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	CEBPA	0	affinity chromatography technology	Tinel M (2003)	1
RNF126	2	UBB	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL5	1	RBX1	2	x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Duda DM (2008), Ohta T (1999), Furukawa M (2002), Tron AE (2012), Tron AE (2012), Yu Y (2004), Huang DT (2009), Wang X (2015), Wang X (2015), Wang X (2015)	10
CUL2	3	PFDN5	0	affinity chromatography technology	Kimura Y (2007)	1
SP1	0	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Hung JJ (2005), Hung JJ (2005), Wang SA (2009), Wang SA (2009)	4
CCNB1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Yang Q (2000), Pines J (1989), Kong M (2000), Amador V (2007), Paulsen MT (2006), Niida H (2005), Pereg Y (2010), Tamura D (2010), Kiviharju-af Haellstroem TM (2007), Pan ZQ (1993), Pan ZQ (1993), Pan ZQ (1993), van Zon W (2010), Desai D (1995), Vazquez-Novelle MD (2010), Smith EM (2008), Poon RY (1996), OConnor PM (1993), Fosbrink M (2009), Linares JF (2011), Varjosalo M (2013), Felzien LK (1998), Toby GG (2003), So J (2015), Huttlin EL (2015), Wan C (2015), Jenkins RH (2014), Hein MY (2015), Hein MY (2015), Voets E (2015), Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	34
SP1	0	TUBB3	3	affinity chromatography technology	Chuang JY (2012)	1
FOXB1	1	SKP2	2	affinity chromatography technology	Li X (2015)	1
CKS1B	0	CCNA1	3	pull down	Radulovic M (2010)	1
BRCA1	7	IMPDH2	3	affinity chromatography technology	Ertych N (2016)	1
PPP1CA	3	ATM	9	affinity chromatography technology	Flores-Delgado G (2007)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
DISC1	6	CCDC88A	3	two hybrid	Camargo LM (2007)	1
FOXO3	1	ATM	9	affinity chromatography technology, affinity chromatography technology, pull down	Tsai WB (2008), Tsai WB (2008), Tsai WB (2008)	3
RNF7	0	CUL4A	2	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
BTRC	1	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013), Fukushima H (2013)	3
SIRT6	2	RUVBL1	2	affinity chromatography technology	Simeoni F (2013)	1
TRIM25	5	ALMS1	13	affinity chromatography technology	Choudhury NR (2017)	1
BTG1	1	CUL1	7	affinity chromatography technology	Sasajima H (2012)	1
ATM	9	NBN	1	unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Cariveau MJ (2007), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Wu J (2012), Wei F (2015)	12
SKP2	2	USP18	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Tokarz S (2004), Tokarz S (2004), Tokarz S (2004), Zhang X (2014)	4
SAMHD1	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014)	2
USP13	2	UFD1	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Chen M (2011)	2
BTG2	0	CUL1	7	affinity chromatography technology	Sasajima H (2012)	1
SKP2	2	FAM83H	6	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	CEP192	5	affinity chromatography technology	Moser SC (2013)	1
LATS2	1	STK3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Bao Y (2009), Couzens AL (2013), Hoa L (2016)	3
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
TP73	2	PFDN5	0	two hybrid, pull down, affinity chromatography technology	Watanabe K (2002), Watanabe K (2002), Watanabe K (2002)	3
RBL2	5	SKP1	0	affinity chromatography technology	Bhattacharya S (2003)	1
CDC20	1	E2F1	0	affinity chromatography technology, affinity chromatography technology	Nath S (2014), Peart MJ (2010)	2
SKP2	2	KIRREL1	0	affinity chromatography technology	Huttlin EL (2017)	1
RNF7	0	CDC34	3	pull down, pull down	He H (2007), Tan M (2010)	2
CCNG2	1	SKP1	0	affinity chromatography technology	Xu G (2008)	1
CDK2	0	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Ruffner H (1999), Ruffner H (1999), Ruffner H (1999), Wang H (1997), Chen Y (1996)	5
BRCA1	7	ESR1	0	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zheng L (2001), Fan S (2001), Fan S (2001), Kawai H (2002), Fan S (2002), Fan S (2002), Nakuci E (2006), Wang C (2005), Wang C (2005), Dizin E (2010), Dizin E (2010), Ma Y (2010), Ma Y (2010), Fan S (2001), Ma YX (2005), Ma YX (2005), Ma YX (2005), Ma Y (2007), Ma Y (2007), Kawai H (2002), Jung YS (2014), Kawai H (2002), Kawai H (2002)	23
KDM5C	9	VHL	0	genetic interference	Shen JP (2017)	1
CUL5	1	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stotland A (2012), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Scherer PC (2016)	5
EP300	36	YY1	7	enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yao YL (2001), Lee JS (1995), Lee JS (1995), Lee JS (1995), Lee JS (1995), Kadeppagari RK (2009), Kadeppagari RK (2009), Kadeppagari RK (2009), Sankar N (2008), Sankar N (2008), Sankar N (2008), Wang CC (2007), Wang CC (2007), Galvin KM (1997)	14
OFD1	3	RAD50	3	affinity chromatography technology	Gupta GD (2015)	1
RBX1	2	UBE2L3	1	pull down, pull down, pull down	Cui Y (2011), Liu Y (2015), Liu Y (2015)	3
CDK2	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
HSP90AA1	7	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	5
SKP1	0	TTC9C	2	two hybrid, affinity chromatography technology	Rolland T (2014), Hein MY (2015)	2
MYC	2	VHL	0	affinity chromatography technology, affinity chromatography technology	Hwang IY (2012), Hwang IY (2012)	2
PHB	0	RB1	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wang S (1999), Wang S (1999), Wang S (1999), Gamble SC (2007)	4
SKP2	2	KDM5C	9	affinity chromatography technology	Huttlin EL (2017)	1
OFD1	3	RUVBL1	2	affinity chromatography technology, pull down	Giorgio G (2007), Giorgio G (2007)	2
EP300	36	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015)	5
CCNB1	3	TP73	2	pull down	Gaiddon C (2003)	1
SP1	0	SKP2	2	affinity chromatography technology	Tapias A (2008)	1
ELAVL1	0	CEBPA	0	affinity chromatography technology	Abdelmohsen K (2009)	1
HSP90AA1	7	RB1	2	genetic interference	Srivas R (2016)	1
TRIM25	5	SMAD4	9	affinity chromatography technology	Choudhury NR (2017)	1
SKP2	2	LRRC40	3	affinity chromatography technology	Huttlin EL (2017)	1
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
CDK2	0	RBL2	5	enzymatic study, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Lacy S (1997), Zhao J (1998), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Howard CM (2000), Huttlin EL (2017)	9
CUL1	7	FBXL18	5	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Reitsma JM (2017)	2
PIM1	2	CDC20	1	affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010)	2
SMAD7	1	COPS5	0	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology	Kim BC (2004), Kim BC (2004), Kim BC (2004), Kim BC (2004)	4
CUL5	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
SMAD7	1	SKP2	2	affinity chromatography technology	Kim TA (2013)	1
DUSP1	1	SKP2	2	affinity chromatography technology	Calvisi DF (2008)	1
AKT1	1	IMPDH2	3	two hybrid, pull down, affinity chromatography technology	Ingley E (2000), Ingley E (2000), Ingley E (2000)	3
CCNE1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
VHL	0	JAK2	1	affinity chromatography technology, affinity chromatography technology	Russell RC (2011), Russell RC (2011)	2
TRIM25	5	DDB1	6	affinity chromatography technology	Choudhury NR (2017)	1
SNRPB2	2	SF3B3	4	biochemical	Havugimana PC (2012)	1
PHB	0	ESR1	0	pull down	He B (2008)	1
RBL2	5	CUL1	7	affinity chromatography technology	Bhattacharya S (2003)	1
RAD50	3	ATM	9	biochemical	Wang Y (2000)	1
SKP2	2	AURKB	2	affinity chromatography technology	Wu J (2015)	1
CDK3	0	SKP1	0	affinity chromatography technology	Varjosalo M (2013)	1
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
ORC1	3	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mendez J (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
MYC	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK3	0	RB1	2	enzymatic study, enzymatic study	Connell-Crowley L (1997), Ren S (2004)	2
CDKN1A	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Fogeron ML (2013)	4
SKP2	2	137529	0	pull down, affinity chromatography technology	Wang W (2004), Calvisi DF (2009)	2
RRM2	2	VHL	0	genetic interference	Shen JP (2017)	1
RUVBL1	2	AR	3	affinity chromatography technology	Kim JH (2007)	1
YWHAB	1	KIAA1671	0	affinity chromatography technology	Couzens AL (2013)	1
COPS6	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
BRCA1	7	BRAP	0	two hybrid, pull down, two hybrid	Li S (1998), Li S (1998), Chen CF (1996)	3
CDK2	0	MYBL2	2	enzymatic study, enzymatic study, enzymatic study	Mueller-Tidow C (2001), Bartsch O (1999), Johnson TK (1999)	3
SNRPB2	2	SKP2	2	biochemical	Havugimana PC (2012)	1
RNF7	0	CUL2	3	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
SMAD4	9	FOXO3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Seoane J (2004), Fu G (2011), Fu G (2011)	4
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
CDC20	1	UBB	4	affinity chromatography technology	Fogeron ML (2013)	1
FBXW8	2	PFDN5	0	affinity chromatography technology	Litterman N (2011)	1
SKP2	2	CDC14B	1	affinity chromatography technology, enzymatic study	Calvisi DF (2009), Rodier G (2008)	2
STIL	3	RRM2	2	bioid	Gupta GD (2015)	1
ATM	9	COPS5	0	enzymatic study	Nagarajan A (2014)	1
RRM2	2	SKP2	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Xiao GG (2008), Xiao GG (2008), Xiao GG (2008)	3
TRIM21	0	SKP1	0	affinity chromatography technology, biochemical	Sabile A (2006), Sabile A (2006)	2
BRCA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
SUGT1	1	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Huttlin EL (2017)	3
NDRG1	2	CDH1	4	affinity chromatography technology, affinity chromatography technology, bioid	Tu LC (2007), Tu LC (2007), Guo Z (2014)	3
FBXW8	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Ponyeam W (2012), Litterman N (2011), Bennett EJ (2010), Liu B (2012), Low TY (2014), Reitsma JM (2017)	7
ELAVL1	0	PHLPP1	4	affinity chromatography technology	Abdelmohsen K (2009)	1
RASSF1	3	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Jiang L (2011), Jiang L (2011), Jiang L (2011)	3
AURKB	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Nguyen HG (2005), Nguyen HG (2005)	2
SKP2	2	ATG2B	11	affinity chromatography technology	Huttlin EL (2017)	1
NBN	1	MTOR	14	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
FOXB1	1	KPNA1	5	affinity chromatography technology	Li X (2015)	1
SMTNL2	3	CCNA2	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radu M (2008), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CUL2	3	ASB2	1	affinity chromatography technology	Nie L (2011)	1
NXF1	0	TOB1	1	affinity chromatography technology	Castello A (2012)	1
ATM	9	RASSF1	3	unspecified method	Kim ST (1999)	1
BRAP	0	PHLPP1	4	two hybrid, pull down	Fatima S (2015), Fatima S (2015)	2
TWIST1	0	YY1	7	pull down	Kotlyar M (2015)	1
CDH1	4	RUVBL1	2	bioid	Guo Z (2014)	1
BRCA1	7	UBE2L3	1	pull down, two hybrid, x-ray crystallography, pull down	Brzovic PS (2003), Christensen DE (2009), Christensen DE (2009), Christensen DE (2009)	4
CDK9	3	AR	3	affinity chromatography technology, pull down	Lee DK (2001), Lee DK (2001)	2
RBX1	2	CUL4A	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical	Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016)	17
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
AR	3	COPS2	5	two hybrid, pull down, affinity chromatography technology	Moehren U (2007), Moehren U (2007), Moehren U (2007)	3
RBX1	2	CDKN1B	1	enzymatic study	Duda DM (2008)	1
CKS1B	0	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Wang W (2003), Sitry D (2002), Zhou W (2009), Ooi LC (2013), Huttlin EL (2017)	5
FOXO3	1	RB1	2	affinity chromatography technology	Li X (2015)	1
CUL5	1	CUL2	3	affinity chromatography technology	Bennett EJ (2010)	1
E2F1	0	MYBL2	2	two hybrid	Giangrande PH (2003)	1
SKP2	2	KANK2	4	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	SIRT2	1	enzymatic study	Movahedi Naini S (2015)	1
SLC9A3R1	2	PHLPP1	4	far western blotting, far western blotting, pull down, affinity chromatography technology	Molina JR (2012), Molina JR (2012), Molina JR (2012), Molina JR (2012)	4
CUL5	1	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	DDB1	6	affinity chromatography technology	Choi SH (2010)	1
PIM1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Cen B (2010), Cen B (2010), Cen B (2010), Cen B (2010)	4
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
FBXW2	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Saiga T (2009), Bennett EJ (2010), Busino L (2003), Liu B (2012), Low TY (2014), Xu J (2017), Reitsma JM (2017)	8
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
SKP2	2	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Marti A (1999), Zhang Z (2005), Farhana L (2002), Salon C (2007), Swarnalatha M (2013)	6
COPS5	0	CCNA2	1	affinity chromatography technology	Bennett EJ (2010)	1
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
COPS6	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
RBL2	5	RAD50	3	affinity chromatography technology, affinity chromatography technology	Kong LJ (2006), Kong LJ (2006)	2
SP1	0	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Gartel AL (2001), Liu T (2007), Gordan JD (2007), Gordan JD (2007), Koshiji M (2005), Koshiji M (2005)	6
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
CDK9	3	CDC34	3	pull down, affinity chromatography technology	Kiernan RE (2001), Kiernan RE (2001)	2
CDKN1A	1	RBL2	5	affinity chromatography technology	Fogeron ML (2013)	1
CDK2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Varjosalo M (2013)	2
FOXO1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang H (2005), Huang H (2005), Huang H (2005), Calvisi DF (2009), Park J (2018), Park J (2018)	6
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
DUSP1	1	CKS1B	0	affinity chromatography technology	Calvisi DF (2008)	1
BRCA1	7	AKT1	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down	Altiok S (1999), Xiang T (2008), Xiang T (2008), Xiang T (2008), Xiang T (2011)	5
FOXO3	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique, pull down	Tsai WB (2010), Tsai WB (2010), Tsai WB (2010), Tsai WB (2010), Tsai WB (2010)	5
EP300	36	WDR59	3	two hybrid	Wang J (2011)	1
RNF7	0	CUL5	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, enzymatic study, pull down, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ohta T (1999), Bennett EJ (2010), Tan M (2008), Kelsall IR (2013), Kelsall IR (2013), Zhou W (2014), Rolland T (2014), Huang DT (2009), Kim DY (2013), Kim DY (2013), Yu H (2011), Bulatov E (2015), Wang X (2015), Wang X (2015), Wang X (2015), Kershaw NJ (2014), Huttlin EL (2017), Kuang P (2016), Kuang P (2016), Zhou W (2017), Zhou W (2017)	21
ELAVL1	0	PIM1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL1	7	BRAP	0	affinity chromatography technology, affinity chromatography technology	Takashima O (2013), Takashima O (2013)	2
WEE1	2	CDKN1B	1	genetic interference	Srivas R (2016)	1
ESR1	0	CDKN1A	1	pull down, pull down, pull down, affinity chromatography technology	Fritah A (2005), Maynadier M (2008), Maynadier M (2008), Kinyamu HK (2003)	4
BTRC	1	WEE1	2	affinity chromatography technology, enzymatic study, pull down, bioid	Watanabe N (2004), Watanabe N (2004), Watanabe N (2004), Coyaud E (2015)	4
ELAVL1	0	RBX1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ORC1	3	CDK2	0	affinity chromatography technology, enzymatic study	Mendez J (2002), Mendez J (2002)	2
NDRG1	2	HSP90AA1	7	affinity chromatography technology	Tu LC (2007)	1
CUL4A	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
CUL1	7	SKIV2L2	0	affinity chromatography technology	Bennett EJ (2010)	1
TWIST1	0	TCF3	7	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	El Ghouzzi V (2000), El Ghouzzi V (2000), Fu J (2011), Teachenor R (2012)	4
COPS5	0	CCNA1	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CUL1	7	KPNA1	5	affinity chromatography technology	Bennett EJ (2010)	1
NXF1	0	HSP90AA1	7	affinity chromatography technology	Castello A (2012)	1
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
PPP1CA	3	SKP1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
SKP2	2	ELF4	0	affinity chromatography technology, enzymatic study	Liu Y (2006), Liu Y (2006)	2
RAG2	0	DDB1	6	biochemical	Kassmeier MD (2011)	1
CCNB1	3	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Hein MY (2015), Huttlin EL (2017)	3
BRAP	0	SKP2	2	pull down, affinity chromatography technology	Lanctot AA (2017), Lanctot AA (2017)	2
CCNA2	1	TP73	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003)	4
COPS5	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Pick E (2012)	7
PSMD9	0	CKS1B	0	fluorescent resonance energy transfe	Xu S (2007)	1
CDC20	1	BTRC	1	affinity chromatography technology	Guardavaccaro D (2008)	1
SKP2	2	SKIV2L2	0	biochemical	Wan C (2015)	1
FBXW8	2	EP300	36	affinity chromatography technology	Kimbrel EA (2009)	1
COPS5	0	SMAD4	9	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wan M (2002), Wan M (2002), Wan M (2002), Wan M (2002), Kim BC (2004), Huang J (2007), Sangadala S (2013), Lee CC (2016), Lee CC (2016)	9
SIRT2	1	SKP2	2	affinity chromatography technology	Li Z (2016)	1
TRIM25	5	RICTOR	4	affinity chromatography technology	Choudhury NR (2017)	1
SMAD7	1	MYC	2	affinity chromatography technology, affinity chromatography technology	Kim TA (2013), Kim TA (2013)	2
LATS2	1	SKP2	2	affinity chromatography technology	Couzens AL (2013)	1
SMAD4	9	AR	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Kang HY (2002), Kang HY (2002), Kang HY (2002), Kang HY (2002)	4
ING3	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
ELAVL1	0	LATS2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
RB1	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nicolas E (2001), Pardo PS (2002), Choubey D (1996), Fajas L (2000), Dyson N (1993), Dyson N (1993), Wu CL (1995), Taniura H (1998), Dai Y (2003), Fedele M (2006), Fedele M (2006), Brown VD (2002), De Blasio A (2005), Chau CM (2008), Dasgupta P (2004), Yang L (2011), Kruetzfeldt M (2005), Harbour JW (1999), Lee SJ (1998), Gao D (2009), Delston RB (2011), Gupta K (2000), Sdek P (2004), Flemington EK (1993), Chang YH (2012), Inoue Y (2007), Inoue Y (2007), Inoue Y (2007), Liu X (2006), Moberg K (1996), Knudsen ES (1996), Brown VD (1999), Brown VD (1999), Whitaker LL (1998), Whitaker LL (1998), Hagemeier C (1993), Bhat UG (1999), Xiao B (2003), Xiao B (2003), Vidal M (1996), Markham D (2006), Markham D (2006), Ianari A (2009), Ianari A (2009), Dhillon NK (2002), Knudsen ES (1997), Knudsen ES (1997), Gery S (2004), Gery S (2004), Kashuba E (2008), Kashuba E (2008), Pearson A (1997), Ginsberg D (1994), Welch PJ (1995), Wang J (2009), Aoki I (2012), Trimarchi JM (1998), Kumari A (2015), Gamell C (2017), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	63
E2F1	0	CDKN1A	1	imaging technique	Devgan V (2005)	1
E2F1	0	SP1	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down	Lin SY (1996), Lin SY (1996), Rotheneder H (1999), Rotheneder H (1999), Karlseder J (1996), Karlseder J (1996), Doetzlhofer A (1999)	7
TP73	2	RB1	2	affinity chromatography technology	Ozaki T (2003)	1
CDKN1B	1	CUL1	7	unspecified method, pull down	Carrano AC (1999), Enchev RI (2012)	2
CCNE1	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McKenzie PP (2003), Shanahan F (1999), Koff A (1992), Koff A (1992), Mayer C (2004), Connor MK (2003), Boudrez A (2000), Varshochi R (2005), Jeong JH (2010), Bustany S (2011), Yeh ES (2006), Hui S (2011), Kim J (2007), Kiviharju-af Haellstroem TM (2007), Abbas T (2007), Nishimura T (2005), Matsumoto Y (2004), Harwell RM (2004), Harwell RM (2004), Peiretti A (2003), Peiretti A (2003), Kim YB (2000), Manenti S (1999), Datta NS (1998), Sheaff RJ (1997), Higashi H (1996), Higashi H (1996), Musgrove EA (1996), Vlach J (1996), Grim JE (2008), Liu S (2009), Ciarallo S (2002), Desai D (1995), Baydoun HH (2010), Baydoun HH (2010), Chu I (2007), Chu I (2007), Levkau B (1998), Poon RY (1996), Zhao J (1998), Zhao J (1998), Larrea MD (2009), Varjosalo M (2013), Varjosalo M (2013), Chan HM (2001), So J (2015), Ungermannova D (2005), Song MS (2011), Huttlin EL (2015), Hein MY (2015), Lin CH (2015), Lin CH (2015), Davis RJ (2017), Huttlin EL (2017)	54
CUL1	7	E2F1	0	affinity chromatography technology, pull down	Marti A (1999), Marti A (1999)	2
ELAVL1	0	KPNA6	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CDKN1B	1	KPNA6	1	pull down	Inuzuka H (2012)	1
ING3	3	RUVBL1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyon Y (2006), Doyon Y (2006), Doyon Y (2004), Hein MY (2015), Huttlin EL (2017)	5
SKP2	2	LRRC58	0	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	JAK2	1	affinity chromatography technology	Gao B (2001)	1
OFD1	3	NBN	1	affinity chromatography technology	Gupta GD (2015)	1
TRIM25	5	FAM83H	6	affinity chromatography technology	Choudhury NR (2017)	1
CDK9	3	RRM2	2	genetic interference	Shen JP (2017)	1
BTRC	1	YWHAB	1	affinity chromatography technology	Coyaud E (2015)	1