Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SPTA1 rs2106089 G benazepril efficacy yes Only when rs4762 genotype (AGT gene) is also taken into account (gene-gene interaction model). Please see study for analysis details - the allele conferring increased likelihood of response/ sensitivity was not clear. Please note, this study reported alleles C>T - here we have represented the complementary alleles on the plus strand (G>A). Allele G is associated with response to benazepril in men with Hypertension as compared to allele A. 21449848 827807008