PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
INPP5D	2	LYN	2	affinity chromatography technology, pull down	Baran CP (2003), Baran CP (2003)	2
FYN	1	SYK	3	affinity chromatography technology, pull down	Deckert M (1998), Deckert M (1998)	2
CD79B	0	TUBA1A	13	affinity chromatography technology	Huttlin EL (2017)	1
TUBA1A	13	TUBB	3	biochemical, biochemical, pull down	Havugimana PC (2012), Kristensen AR (2012), Wang W (2014)	3
SRC	2	RPS6KB2	3	enzymatic study	Rebholz H (2006)	1
LCK	0	PAG1	5	pull down	Brdicka T (2000)	1
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
VAV2	6	CBLB	3	two hybrid	Bustelo XR (1997)	1
10748	0	SYK	3	affinity chromatography technology	McVicar DW (1998)	1
GRB2	2	CD22	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Poe JC (2000), Poe JC (2000), Otipoby KL (2001)	3
SLA	2	VAV1	2	affinity chromatography technology, pull down	Sosinowski T (2000), Sosinowski T (2000)	2
CBLB	3	VAV1	2	affinity chromatography technology, two hybrid, pull down, far western blotting, affinity chromatography technology	Sattler M (2002), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997)	5
LCK	0	SYK	3	affinity chromatography technology, pull down, two hybrid	Thome M (1995), Thome M (1995), Moon KD (2005)	3
EGFR	5	SLA	2	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
HDAC6	0	ERBB4	5	protein complementation assay	Deribe YL (2009)	1
SRC	2	EPOR	3	affinity chromatography technology	Liang K (2010)	1
TLR9	2	TRAF6	0	affinity chromatography technology	Yang M (2011)	1
SYK	3	INPP5D	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012), de Castro RO (2012)	3
EGFR	5	LYN	2	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
ITGA4	4	SYK	3	affinity chromatography technology	Byron A (2012)	1
PIK3R2	3	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Martelli MP (2001)	3
CD4	1	RPS10	0	affinity chromatography technology	Bernhard OK (2004)	1
TNFRSF1A	3	TRAF3	1	pull down	Mosialos G (1995)	1
CBL	7	NCK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Erdreich-Epstein A (1999), Miyoshi-Akiyama T (2001), Izadi KD (1998), Izadi KD (1998), Wunderlich L (1999), Shishido T (2000), Okabe S (2006), Adler CE (2000), Adler CE (2000), Buvall L (2013), Buvall L (2013), Buvall L (2013), Buvall L (2013)	13
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
SIT1	1	FYN	1	affinity chromatography technology	Marie-Cardine A (1999)	1
TRAF3IP2	0	IL17RA	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian Y (2007), Wu NL (2014), Boisson B (2013), Ma C (2017), Ma C (2017)	5
CD19	3	VAV1	2	affinity chromatography technology, affinity chromatography technology	Weng WK (1994), Lottin-Divoux S (2006)	2
MAPT	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Souter S (2009), Souter S (2009), Souter S (2009)	3
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
SH3BP2	4	CBL	7	pull down, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
NCK1	0	TBK1	1	pull down, affinity chromatography technology	Chou MM (1995), Chou MM (1995)	2
CBL	7	TUBB	3	affinity chromatography technology, affinity chromatography technology	Teckchandani AM (2005), Brehme M (2009)	2
CD3E	0	LCK	0	affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003)	2
TNFRSF1A	3	SYK	3	affinity chromatography technology	Lee CK (2015)	1
TRAF3IP2	0	TRAF6	0	enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Liu C (2009), Kanamori M (2002), Kanamori M (2002), Kanamori M (2002), Qian Y (2007), Qu F (2012), Wu NL (2014), Wu NL (2014), Rolland T (2014), Garg AV (2013), Sun D (2011), Yu H (2011)	12
TLR4	5	TRAF6	0	affinity chromatography technology	Yang M (2011)	1
TICAM1	3	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Jiang Z (2004), Nguyen VP (2014)	2
ERBB3	3	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Schulze WX (2006), Jones RB (2006), Li J (2013)	3
STAT3	0	LCK	0	two hybrid	Grossmann A (2015)	1
GRB2	2	VAV2	6	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Bourguignon LY (2001)	2
HDAC9	7	HDAC3	5	pull down, affinity chromatography technology	Petrie K (2003), Zhou X (2000)	2
PXN	1	PTK2B	6	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hiregowdara D (1997), Hiregowdara D (1997), Matsuya M (1998), Matsuya M (1998), Anfosso F (2001), Ivankovic-Dikic I (2000)	6
PLCG2	11	SYK	3	affinity chromatography technology	Guo B (2000)	1
LYN	2	RPS6KB1	1	enzymatic study	Rebholz H (2006)	1
ERBB2	6	FGR	1	unspecified method	Jones RB (2006)	1
SYK	3	CALM1	0	enzymatic study, enzymatic study	Brunati AM (1988), Meggio F (1987)	2
CBL	7	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Lin H (2001), Hartley D (1995), Feshchenko EA (2004), Alcazar I (2009), Brehme M (2009), Brehme M (2009), Grossmann A (2015)	7
CTTN	1	HDAC6	0	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Zhang X (2007), Zhang X (2007), Zhang X (2007), Kaluza D (2011), Kaluza D (2011)	5
LCP2	0	APP	1	pull down	Olah J (2011)	1
TBK1	1	APP	1	pull down	Olah J (2011)	1
SH3BP2	4	PLCG1	6	pull down, far western blotting	Deckert M (1998), Jevremovic D (2001)	2
PTK2B	6	FYN	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ganju RK (1997), Katagiri T (2000), Qian D (1997), Qian D (1997), Marie-Cardine A (1999)	5
VCAM1	2	GRB2	2	affinity chromatography technology	Humphries JD (2009)	1
LCP2	0	PAG1	5	pull down	Brdicka T (2000)	1
ITGA4	4	FCGR2A	0	affinity chromatography technology	Byron A (2012)	1
APP	1	MAPT	1	pull down, unspecified method	Guo JP (2006), Guo JP (2006)	2
CSF3R	2	SYK	3	affinity chromatography technology	Corey SJ (1994)	1
CRKL	1	PXN	1	affinity chromatography technology, pull down, affinity chromatography technology	Salgia R (1995), Salgia R (1995), Nishiya N (2001)	3
VAV1	2	PAG1	5	pull down	Brdicka T (2000)	1
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
LYN	2	PTPN6	0	pull down	Yoshida K (1999)	1
NEDD4	2	HGS	5	enzymatic study, affinity chromatography technology, affinity chromatography technology	Katz M (2002), Sun Y (2013), Tan X (2015)	3
VAV1	2	LCP2	0	affinity chromatography technology, pull down, affinity chromatography technology	Raab M (1997), Onodera H (1996), Shen M (2009)	3
LCP2	0	GRAP2	0	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, x-ray crystallography, biochemical, affinity chromatography technology, unspecified method, two hybrid, two hybrid	Rual JF (2005), Ellis JH (2000), Liu SK (1999), Liu SK (1999), Liu SK (1999), Liu SK (1999), Asada H (1999), Asada H (1999), Berry DM (2002), Berry DM (2002), Berry DM (2002), Harkiolaki M (2003), Yankee TM (2003), Yankee TM (2003), Seet BT (2007), Rolland T (2014), Yu H (2011)	17
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
TUBG1	2	RPS10	0	affinity chromatography technology	Fogeron ML (2013)	1
TRAF6	0	TBK1	1	affinity chromatography technology, affinity chromatography technology, pull down	Cai B (2017), Fang R (2017), Fang R (2017)	3
TRAF6	0	SRC	2	affinity chromatography technology, pull down	Wong BR (1999), Liu A (2012)	2
PTK2	2	FGR	1	affinity chromatography technology	Relou IA (2003)	1
CD79A	2	SYK	3	pull down	Kurosaki T (1995)	1
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
TLR3	2	TBK1	1	affinity chromatography technology, affinity chromatography technology	Yang M (2011), Zinngrebe J (2016)	2
CD4	1	SYK	3	affinity chromatography technology	Thome M (1995)	1
PTPN6	0	LAT	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016), Matalon O (2016)	3
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
SYK	3	SLC4A1	7	enzymatic study	Sada K (2000)	1
ERBB4	5	PIK3R2	3	affinity chromatography technology	Schulze WX (2006)	1
ERBB4	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Kiuchi T (2014)	2
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
CBLB	3	PLCG2	11	affinity chromatography technology	Yasuda T (2002)	1
SYK	3	PRKD1	7	affinity chromatography technology	Sidorenko SP (1996)	1
PLCG1	6	PRKD1	7	affinity chromatography technology	Sidorenko SP (1996)	1
SLA	2	SYK	3	affinity chromatography technology	Tang J (1999)	1
CD72	2	BLNK	2	affinity chromatography technology	Fusaki N (2000)	1
CD4	1	HGS	5	affinity chromatography technology	Barriere H (2007)	1
PTK2	2	SYK	3	affinity chromatography technology, affinity chromatography technology	Chung J (1997), Sada K (1997)	2
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
GRAP2	0	CBLB	3	two hybrid	Grossmann A (2015)	1
PXN	1	ITGB3	6	pull down	Pfaff M (2001)	1
ERBB3	3	TUBB	3	affinity chromatography technology	Li J (2013)	1
BTK	1	CBL	7	pull down, x-ray crystallography, unspecified method, affinity chromatography technology	Cory GO (1995), Tzeng SR (2000), Patel HV (1997), Morrogh LM (1999)	4
SYK	3	ITGB2	4	affinity chromatography technology	Miura Y (2000)	1
TICAM1	3	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li S (2011), Piao W (2009), Sato S (2003), Sato S (2003), Hu YH (2015), Cai B (2017)	6
STAT3	0	SH2D2A	2	two hybrid	Grossmann A (2015)	1
PLCG1	6	LAT	0	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Zhang W (1998), Paz PE (2001), Paz PE (2001), Zhang W (1998), Jiang Y (2007), Braiman A (2006), Braiman A (2006), Matalon O (2016), Matalon O (2016)	9
PXN	1	FYN	1	affinity chromatography technology	Chen LM (2000)	1
FCGR2A	0	LAT	0	affinity chromatography technology	Tridandapani S (2000)	1
GRB2	2	BTK	1	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
ERBB2	6	SYK	3	unspecified method	Jones RB (2006)	1
PXN	1	HDAC6	0	imaging technique, fluorescent resonance energy transfe, affinity chromatography technology	Deakin NO (2014), Deakin NO (2014), Deakin NO (2014)	3
BLNK	2	NCK1	0	affinity chromatography technology, imaging technique	Fu C (1998), Chen TC (2014)	2
SYK	3	HDAC2	1	pull down	Wang L (2005)	1
TRAIP	0	MAP3K7	2	affinity chromatography technology	Kong QZ (2016)	1
SYK	3	TRAIP	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Zhou Q (2009), Zhou Q (2009), Zhou Q (2009)	3
CALM1	0	MAPT	1	pull down	Padilla R (1990)	1
TLR3	2	TRAF3	1	affinity chromatography technology	Li S (2011)	1
IL17RA	3	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Ma C (2017), Ma C (2017)	2
PIK3R1	6	INPP5D	2	affinity chromatography technology	Zhang S (1999)	1
SP1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Won J (2002), Zhang Y (2002), Sun JM (2002), Glasspool RM (2005), Duan H (2005), Sekhavat A (2007), Itoh Y (2007), Marshall GM (2010), Tsai PF (2011), Schnur N (2007)	10
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
HGS	5	APP	1	pull down, pull down, pull down	Pridgeon JW (2009), Olah J (2011), Virok DP (2011)	3
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
EPOR	3	GRB2	2	pull down, pull down, affinity chromatography technology	Tauchi T (1995), Feng GS (1996), Barber DL (1997)	3
NCK1	0	INPP5D	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
SEC23B	0	PXN	1	biochemical	Kristensen AR (2012)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
TLR4	5	TBK1	1	affinity chromatography technology	Yang M (2011)	1
PTK2	2	ITGA4	4	affinity chromatography technology	Liu S (2002)	1
SH2D2A	2	SRC	2	unspecified method, affinity chromatography technology	Sun Z (2012), Sun Z (2012)	2
ERBB3	3	PTK2B	6	affinity chromatography technology	Verma N (2017)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
EPOR	3	SYK	3	affinity chromatography technology	Duprez V (1998)	1
FYN	1	MAPT	1	affinity chromatography technology, pull down, pull down, enzymatic study	Klein C (2002), Klein C (2002), Bhaskar K (2005), Bhaskar K (2005)	4
SYK	3	TBK1	1	affinity chromatography technology	Lin YC (2013)	1
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CD3E	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	de Aos I (1997), Alcazar I (2009)	2
PLCG2	11	VAV1	2	affinity chromatography technology	Guo B (2000)	1
VCAM1	2	PIK3R2	3	affinity chromatography technology	Humphries JD (2009)	1
SRC	2	SYK	3	enzymatic study, affinity chromatography technology, enzymatic study	Kurosaki T (1994), Asazuma N (1997), Hirose M (2004)	3
ERBB3	3	VAV2	6	unspecified method	Jones RB (2006)	1
CBLB	3	LCK	0	affinity chromatography technology	Kumar S (2011)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
SYK	3	SYK	3	x-ray crystallography, enzymatic study, enzymatic study	Fuetterer K (1998), Lebouvier T (2008), Eliopoulos AG (2006)	3
HCLS1	0	CD79A	2	affinity chromatography technology	Hata D (1994)	1
NEDD4	2	PTK2B	6	affinity chromatography technology	Verma N (2017)	1
BLNK	2	SYK	3	affinity chromatography technology, affinity chromatography technology	Oellerich T (2011), Janda E (2011)	2
TLR9	2	TRAF3	1	affinity chromatography technology	Li S (2011)	1
PLCG2	11	PLCG1	6	imaging technique	Chen TC (2014)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
FLNA	10	CALM1	0	affinity chromatography technology	Hein MY (2015)	1
SYK	3	MAPT	1	enzymatic study, affinity chromatography technology	Lebouvier T (2008), Lebouvier T (2008)	2
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
PTK2B	6	GRB2	2	affinity chromatography technology, affinity chromatography technology	Blaukat A (1999), Bruzzaniti A (2009)	2
VCAM1	2	SYK	3	affinity chromatography technology	Humphries JD (2009)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
GRB2	2	HCLS1	0	pull down	Takemoto Y (1998)	1
CD22	3	SYK	3	affinity chromatography technology	Law CL (1996)	1
TRAIP	0	TBK1	1	affinity chromatography technology	Zhang M (2012)	1
LAT	0	PIK3R1	6	affinity chromatography technology, pull down	Paz PE (2001), Paz PE (2001)	2
FLNA	10	DPP9	4	pull down, affinity chromatography technology, imaging technique	Justa-Schuch D (2016), Justa-Schuch D (2016), Justa-Schuch D (2016)	3
SYK	3	CD72	2	enzymatic study	Adachi T (1998)	1
FCGR3A	0	SYK	3	affinity chromatography technology, enzymatic study	Darby C (1994), Darby C (1994)	2
FGR	1	CBL	7	affinity chromatography technology	Melander F (2003)	1
HDAC3	5	SP1	0	affinity chromatography technology	Huang W (2006)	1
SYK	3	TUBA1A	13	enzymatic study	Faruki S (2000)	1
VAV1	2	PTPN6	0	pull down	Kon-Kozlowski M (1996)	1
TLR3	2	SYK	3	affinity chromatography technology	Lin YC (2013)	1
PLCG1	6	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
PLCG1	6	ERBB2	6	affinity chromatography technology, biochemical, unspecified method	Peles E (1991), Arteaga CL (1991), Jones RB (2006)	3
STAT3	0	FYN	1	pull down	Schreiner SJ (2002)	1
CBLB	3	MYD88	1	affinity chromatography technology	Han C (2010)	1
HDAC4	10	HDAC3	5	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Grozinger CM (1999), Fischle W (2002), Fischle W (2002), Fischle W (2002), Fischle W (2001), Grozinger CM (2000), Wang X (2008)	7
MYD88	1	TRAF6	0	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fitzgerald KA (2001), Zhou J (2011), Zhou J (2011), Zhang X (2013), Zhang X (2013), Hirata Y (2006)	6
FYN	1	VAV2	6	two hybrid	Tartare-Deckert S (2001)	1
LAT	0	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Paz PE (2001), Zhang W (1998), Perez-Villar JJ (2002), Motto DG (1994), Houtman JC (2006)	5
TLR4	5	SYK	3	affinity chromatography technology	Lin YC (2013)	1
ITGA4	4	GRB2	2	affinity chromatography technology	Byron A (2012)	1
HDAC4	10	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
FCGR2A	0	CBL	7	biochemical	Marois L (2009)	1
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
APP	1	TUBG1	2	pull down	Virok DP (2011)	1
SIT1	1	SYK	3	affinity chromatography technology	Marie-Cardine A (1999)	1
TICAM1	3	TRAF6	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Sasai M (2010), Sasai M (2010), Jiang Z (2004), Wang YY (2004), Sato S (2003), Sato S (2003), Sato S (2003), Takaki H (2009), Verstak B (2014), Hu YH (2015)	10
STAT3	0	SH3BP2	4	two hybrid	Grossmann A (2015)	1
TRAF3	1	CBLB	3	affinity chromatography technology	Qiao G (2007)	1
LCK	0	LAT	0	biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Jiang Y (2007), Jiang Y (2007)	4
CD19	3	CD79B	0	affinity chromatography technology	Carter RH (1997)	1
SYK	3	PIK3R1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Moon KD (2005), Moon KD (2005), Moon KD (2005), Moon KD (2005), Huang ZY (2006)	5
TRAF6	0	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Ishitani T (2003), Takaesu G (2000), Ninomiya-Tsuji J (1999), Takaesu G (2001), Mochida Y (2000), Mochida Y (2000), Walsh MC (2008), Sorrentino A (2008), Frobose H (2006), Ishitani T (2003), Xia ZP (2009), Jiang Z (2003), Jiang Z (2003), Yamazaki K (2009), Yamazaki K (2009), Jiang Z (2002), Jiang Z (2002), Cui W (2012), Jiang Z (2003), Minoda Y (2009), Gao D (2009), Lee HJ (2012), Hirata Y (2006), Hu MM (2014), Fujikawa H (2013), Sun D (2011), Li W (2015), Lin J (2015), Lee Y (2016), Ji YX (2016), Ji YX (2016), Ji YX (2016), Ji YX (2016)	33
USP25	0	SYK	3	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Cholay M (2010), Cholay M (2010), Cholay M (2010), Cholay M (2010), Rolland T (2014), Yu H (2011)	6
SYK	3	GRAP2	0	affinity chromatography technology	de Castro RO (2012)	1
GRB2	2	CSF3R	2	affinity chromatography technology, far western blotting, protein complementation assay, pull down, unspecified method	Ward AC (1998), Ward AC (1998), Erkeland SJ (2007), Kendrick TS (2004), Kendrick TS (2004)	5
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
TLR4	5	TRAF3	1	affinity chromatography technology	Li S (2011)	1
EGFR	5	TNFRSF1A	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SYK	3	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yamada T (2001), Lin YC (2013), Wu NL (2014)	3
CBLB	3	PTK2B	6	affinity chromatography technology	Fan Y (2014)	1
SRC	2	PTK2B	6	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Keely SJ (2000), Kumar S (1999), Dikic I (1996), Dikic I (1996), Bruzzaniti A (2009)	5
TRIM15	0	SYK	3	protein complementation assay	Lee OH (2015)	1
NCK1	0	PTK2	2	pull down, affinity chromatography technology, pull down	Minegishi M (1996), Goicoechea SM (2002), Goicoechea SM (2002)	3
RPS6KB2	3	TUBB	3	affinity chromatography technology	Roy R (2014)	1
EGFR	5	TUBB	3	affinity chromatography technology	Foerster S (2013)	1
EGFR	5	HDAC1	4	affinity chromatography technology	Yao Z (2017)	1
GRB2	2	FLNA	10	affinity chromatography technology	Bisson N (2011)	1
CD79B	0	ERBB2	6	affinity chromatography technology	Huttlin EL (2017)	1
MYD88	1	SYK	3	affinity chromatography technology	Lin YC (2013)	1
VCAM1	2	TUBB	3	affinity chromatography technology	Humphries JD (2009)	1
SYK	3	GRM1	4	affinity chromatography technology, affinity chromatography technology	Hirose M (2004), Hirose M (2004)	2
VAV1	2	EGFR	5	affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Moores SL (2000), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	4
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
CBL	7	PXN	1	affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Salgia R (1996)	2
ERBB3	3	HGS	5	affinity chromatography technology, affinity chromatography technology	Fosdahl AM (2017), Fosdahl AM (2017)	2
VAV1	2	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bertagnolo V (1998), Bertagnolo V (1998), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
SH3BP2	4	LAT	0	pull down, affinity chromatography technology	Deckert M (1998), Jevremovic D (2001)	2
VAV1	2	MS4A2	1	affinity chromatography technology	Song JS (1996)	1
TLR9	2	SYK	3	affinity chromatography technology	Lin YC (2013)	1
LYN	2	PIK3CG	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Pigazzi A (1999), Marcilla A (1995), Marcilla A (1995), Marcilla A (1995)	4
PTK2B	6	ITGB3	6	pull down	Pfaff M (2001)	1
SYK	3	RPS10	0	two hybrid	Moon KD (2005)	1
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
HDAC6	0	ERBB2	6	protein complementation assay	Deribe YL (2009)	1
INPP5D	2	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
RPS6KB1	1	APP	1	pull down	Olah J (2011)	1
FYN	1	SH3BP2	4	two hybrid	Deckert M (1998)	1
LCP2	0	NCK1	0	affinity chromatography technology, pull down, affinity chromatography technology	Shim EK (2004), Wunderlich L (1999), de Castro RO (2012)	3
PEAR1	5	SYK	3	affinity chromatography technology	Scheib JL (2012)	1
MYD88	1	TLR9	2	two hybrid, affinity chromatography technology	Chuang TH (2004), Yang M (2011)	2
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
PTK2	2	FYN	1	affinity chromatography technology, x-ray crystallography	Messina S (2003), Arold ST (2001)	2
TRAIP	0	APP	1	pull down	Olah J (2011)	1
SYK	3	HDAC9	7	affinity chromatography technology, pull down	Wang L (2005), Wang L (2005)	2
EGFR	5	PTK2B	6	affinity chromatography technology, affinity chromatography technology	Keely SJ (2000), Ivankovic-Dikic I (2000)	2
BLNK	2	VAV1	2	affinity chromatography technology	Fu C (1998)	1
ERBB2	6	SH3BP2	4	unspecified method	Jones RB (2006)	1
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
APP	1	SRC	2	affinity chromatography technology	Austin SA (2009)	1
ERBB3	3	SYK	3	unspecified method	Jones RB (2006)	1
TUBB	3	SYK	3	affinity chromatography technology	Fernandez JA (1999)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
BTK	1	TLR9	2	two hybrid	Jefferies CA (2003)	1
SRC	2	LYN	2	unspecified method	Pirozzi G (1997)	1
RPS10	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
LAT	0	CBL	7	affinity chromatography technology	Jiang Y (2007)	1
PTPN6	0	CD72	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ishida I (2003), Adachi T (1998), Adachi T (1998), Kumanogoh A (2000)	4
SYK	3	RPS6KB2	3	enzymatic study	Rebholz H (2006)	1
SYK	3	FAM46A	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
RHOU	0	SYK	3	pull down	Dart AE (2015)	1
PXN	1	NCK1	0	pull down	Turner CE (1999)	1
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
HDAC3	5	PIK3R1	6	affinity chromatography technology	Alam S (2011)	1
VAV2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moores SL (2000), Tong J (2009), Duan L (2011), Duan L (2011), Tong J (2008), Tong J (2014)	6
TRAF3IP2	0	MAP3K7	2	affinity chromatography technology	Qian Y (2007)	1
SYK	3	UBASH3B	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	de Castro RO (2012), de Castro RO (2012), Thomas DH (2010), Thomas DH (2010), Thomas DH (2010)	5
SYK	3	TRAF3IP2	0	affinity chromatography technology, affinity chromatography technology	Wu NL (2014), Wu NL (2014)	2
SRC	2	RPS6KB1	1	enzymatic study	Rebholz H (2006)	1
LCK	0	PTK2B	6	affinity chromatography technology	Ganju RK (1997)	1
STAT3	0	HDAC2	1	affinity chromatography technology, imaging technique	Yuan ZL (2005), Chen TC (2014)	2
ITGA4	4	RPS10	0	affinity chromatography technology	Byron A (2012)	1
BTK	1	SYK	3	affinity chromatography technology	Morrogh LM (1999)	1
SYK	3	PTK2B	6	affinity chromatography technology	Ganju RK (2000)	1
EGFR	5	UBASH3B	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Raguz J (2007), Raguz J (2007), Tong J (2008), Foerster S (2013), Li J (2013), Tong J (2014), Li J (2013)	8
GRAP2	0	BLNK	2	pull down, unspecified method, affinity chromatography technology	Berry DM (2002), Berry DM (2002), Yankee TM (2003)	3
VCAM1	2	FLNA	10	affinity chromatography technology	Humphries JD (2009)	1
BLNK	2	CBL	7	affinity chromatography technology, far western blotting	Yasuda T (2000), Yasuda T (2000)	2
SH3BP2	4	SRC	2	affinity chromatography technology	GuezGuez A (2010)	1
FYN	1	PLCG2	11	pull down	Pleiman CM (1993)	1
HDAC1	4	UBASH3B	4	affinity chromatography technology	Zhang Y (1998)	1
NEDD4	2	CBLB	3	pull down, affinity chromatography technology, affinity chromatography technology	Magnifico A (2003), Magnifico A (2003), Magnifico A (2003)	3
PLCG1	6	PTK2	2	affinity chromatography technology	Zhang X (1999)	1
SYK	3	HDAC6	0	affinity chromatography technology, pull down	Wang L (2005), Wang L (2005)	2
ITGA4	4	CBL	7	affinity chromatography technology	Byron A (2012)	1
SIRPB1	6	TYROBP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dietrich J (2000), Tomasello E (2000), Tomasello E (2000)	3
SRC	2	GRM1	4	affinity chromatography technology, affinity chromatography technology	Hirose M (2004), Hirose M (2004)	2
CD4	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Hawash IY (2002), Foti M (2002), Bernhard OK (2004), Loewenberg M (2006), Py B (2007)	5
ERBB2	6	VAV1	2	unspecified method	Jones RB (2006)	1
NEDD4	2	TBK1	1	pull down	Persaud A (2009)	1
STAT3	0	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Wei J (2012), Wei J (2012)	2
SYK	3	HCLS1	0	imaging technique	Chen TC (2014)	1
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
SLA	2	LAT	0	affinity chromatography technology	Tang J (1999)	1
EGFR	5	ITGB2	4	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PTK2	2	SRC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hecker TP (2002), Angers-Loustau A (1999), Relou IA (2003), Messina S (2003), Lebrun P (1998), Ponnala S (2011), Grossmann A (2015), Chen TC (2014), Lee J (2013), Reiske HR (2000)	11
USP25	0	APP	1	affinity chromatography technology	Jung ES (2015)	1
LAT	0	VAV1	2	pull down, pull down, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Perez-Villar JJ (2002)	3
CTTN	1	PTK2	2	affinity chromatography technology	Bharti S (2007)	1
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
BTK	1	PLCG2	11	affinity chromatography technology, affinity chromatography technology	Yasuda T (2002), Guo B (2000)	2
HDAC9	7	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhou X (2000), Morrison BE (2006), Sparrow DB (1999), Sparrow DB (1999)	4
SP1	0	HDAC4	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mottet D (2009), Mottet D (2009), Wilson AJ (2008)	3
ITGB3	6	PTK2	2	pull down, affinity chromatography technology, affinity chromatography technology	Eliceiri BP (2002), Chung J (1997), Lee DY (2010)	3
CD4	1	TUBB	3	affinity chromatography technology	Bernhard OK (2004)	1
TLR9	2	TBK1	1	affinity chromatography technology	Yang M (2011)	1
BLNK	2	LYN	2	affinity chromatography technology	Oellerich T (2011)	1
TLR3	2	MAP3K7	2	affinity chromatography technology, affinity chromatography technology	Jiang Z (2003), Cusson-Hermance N (2005)	2
VAV1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
BTK	1	PRKD1	7	affinity chromatography technology, affinity chromatography technology, pull down	Johannes FJ (1999), Johannes FJ (1999), Johannes FJ (1999)	3
PIK3R2	3	APP	1	pull down	Olah J (2011)	1
STAT3	0	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kojima H (2005), Kojima H (2005), Kojima H (2005)	3
TUBG1	2	TUBB	3	affinity chromatography technology	Fogeron ML (2013)	1
BTK	1	BLNK	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yasuda T (2002), Hashimoto S (1999), Hashimoto S (1999), Oellerich T (2011), Janda E (2011)	5
STAT3	0	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Tsuruma R (2008), Kato M (2015)	5
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
SYK	3	MS4A2	1	pull down	Kihara H (1994)	1
FCRL3	2	PTPN6	0	affinity chromatography technology, pull down	Xu MJ (2002), Xu MJ (2002)	2
SP1	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin S (2006), Zhang Y (2007), Zhang Y (2007), Proietti CJ (2011)	4
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
PLCG2	11	PRKD1	7	affinity chromatography technology	Sidorenko SP (1996)	1
STAT3	0	LYN	2	pull down	Schreiner SJ (2002)	1
MYD88	1	BTK	1	affinity chromatography technology	Jefferies CA (2003)	1
CD19	3	CD79A	2	affinity chromatography technology	Carter RH (1997)	1
PTPRO	3	SYK	3	affinity chromatography technology	Hsu SH (2013)	1
INPP5D	2	CD22	3	affinity chromatography technology, affinity chromatography technology	Poe JC (2000), Poe JC (2000)	2
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
ITGB3	6	SYK	3	affinity chromatography technology	Saci A (2000)	1
EGFR	5	FGR	1	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
UBASH3B	4	MAPT	1	enzymatic study, affinity chromatography technology	Pei JJ (2006), Pei JJ (2006)	2
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
CRKL	1	SYK	3	affinity chromatography technology, pull down	Oda A (2001), Oda A (2001)	2
PTPN6	0	PAG1	5	pull down	Brdicka T (2000)	1
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
CD79B	0	SYK	3	pull down	Kurosaki T (1995)	1
PXN	1	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovacic-Milivojevic B (2001), Matsuya M (1998), Turner CE (1999), Liu S (2002), Liu S (2002), Mazaki Y (1997), Zheng C (1998), Brown MC (1996), Fujita H (1998), Zhang Z (1999), Wang JF (2000), Ivankovic-Dikic I (2000)	12
TRAF6	0	MAPT	1	enzymatic study	Babu JR (2005)	1
CD19	3	CD22	3	affinity chromatography technology	Carter RH (1997)	1
TRAF3IP2	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian Y (2002), Qian Y (2004), Boisson B (2013)	3
TUBA1A	13	CBL	7	affinity chromatography technology	Teckchandani AM (2005)	1
CBL	7	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Bertagnolo V (2001), Miura-Shimura Y (2003), Simmons A (2005), Shen M (2009), Shen M (2009), Lottin-Divoux S (2006), Lottin-Divoux S (2006), Peterson ME (2008)	12
SYK	3	RPS6KB1	1	enzymatic study	Rebholz H (2006)	1
TUBA1A	13	MAPT	1	affinity chromatography technology	Seiberlich V (2012)	1
EGFR	5	GRAP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
PIK3R2	3	RPS10	0	affinity chromatography technology	Brehme M (2009)	1
PTPN6	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
BTK	1	RPS6KB1	1	enzymatic study	Rebholz H (2006)	1
FCRL3	2	SYK	3	pull down	Xu MJ (2002)	1
TRAF6	0	APP	1	pull down	Olah J (2011)	1
SYK	3	PIK3CG	3	affinity chromatography technology	Marcilla A (1995)	1
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
FLNA	10	CTTN	1	affinity chromatography technology	Hein MY (2015)	1
SYK	3	HGS	5	enzymatic study	Gasparrini F (2012)	1
ERBB2	6	VAV2	6	unspecified method	Jones RB (2006)	1
GRASP	1	SRC	2	affinity chromatography technology, enzymatic study	Hirose M (2004), Hirose M (2004)	2
SYK	3	PXN	1	affinity chromatography technology	Fernandez R (1998)	1
VAV1	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song JS (1996), Ye ZS (1994), Ye ZS (1994), Germani A (1999), Lee IS (1997)	5
EGFR	5	ERBB4	5	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Meijer IM (2013), Kiuchi T (2014), Kiuchi T (2014)	3
CBLB	3	TICAM1	3	affinity chromatography technology	Han C (2010)	1
HDAC6	0	TUBB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao Z (2010), Zhao Z (2010), New M (2013), Watson GW (2016)	4
SYK	3	ERBB4	5	unspecified method	Jones RB (2006)	1
CD79A	2	CD79B	0	affinity chromatography technology, pull down	Schamel WW (2003), Pao LI (1998)	2
CBL	7	SYK	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Lupher ML (1998), Lupher ML (1998), Bertagnolo V (2001), Melander F (2003), Macglashan D (2004), Rao N (2001), Rao N (2001), Yankee TM (1999), Saci A (2000), Moon KD (2005), Lottin-Divoux S (2006), Grossmann AH (2004), Ota S (2000), Ota S (2000), Panchamoorthy G (1996), Marcilla A (1995), Justa-Schuch D (2016)	17
CSF3R	2	LYN	2	affinity chromatography technology	Corey SJ (1994)	1
TRAF3IP2	0	TBK1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Qu F (2012), Qu F (2012), Qu F (2012)	3
FCER1A	0	SYK	3	affinity chromatography technology	Ota Y (1997)	1
FCGR3A	0	FCGR1A	0	imaging technique	Chen TC (2014)	1
PTK2	2	LYN	2	affinity chromatography technology, two hybrid	Chung J (1997), Grossmann A (2015)	2
CRKL	1	FCGR1A	0	affinity chromatography technology	Kyono WT (1998)	1
FCGR2A	0	LYN	2	affinity chromatography technology	Ibarrola I (1997)	1
SYK	3	VAV2	6	two hybrid	Tartare-Deckert S (2001)	1
SRC	2	FLNA	10	two hybrid	Bandyopadhyay S (2010)	1
BTK	1	FLNA	10	affinity chromatography technology	Li Y (2011)	1
SYK	3	TUBG1	2	biochemical, affinity chromatography technology	Zyss D (2005), Zyss D (2005)	2
CBLB	3	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
PIK3R1	6	EPOR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Damen JE (1995), Damen JE (1995), Montoye T (2005), Bulut GB (2013)	6
EGFR	5	SH2D2A	2	unspecified method	Jones RB (2006)	1
GRB2	2	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid	Sieg DJ (2000), Angers-Loustau A (1999), Hildebrand JD (1996), Messina S (2003), Arold ST (2002), Vinayagam A (2011)	6
NEDD4	2	SYK	3	pull down	Persaud A (2009)	1
SYK	3	TRAF3	1	affinity chromatography technology	Lin YC (2013)	1
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
HCLS1	0	FGR	1	pull down	Brunati AM (1999)	1
MYD88	1	TLR4	5	two hybrid, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, protein complementation assay, protein complementation assay, affinity chromatography technology	Chuang TH (2004), Doyle SE (2003), Rhee SH (2000), Fitzgerald KA (2001), Ulrichts P (2007), Ulrichts P (2008), Ulrichts P (2010), Yang M (2011)	8
DPP9	4	SYK	3	imaging technique, pull down, enzymatic study	Justa-Schuch D (2016), Justa-Schuch D (2016), Justa-Schuch D (2016)	3
TRIM15	0	SRC	2	protein complementation assay, affinity chromatography technology	Lee OH (2015), Lee OH (2015)	2
ERBB2	6	SH2D2A	2	unspecified method	Jones RB (2006)	1
TRAIP	0	TRAF3	1	affinity chromatography technology, affinity chromatography technology	Besse A (2007), Zhang M (2012)	2
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
PTK2	2	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay	Sieg DJ (2000), Kotlyar M (2015), Petschnigg J (2014)	3
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
HDAC6	0	MAPT	1	pull down, affinity chromatography technology, affinity chromatography technology	Ding H (2008), Ding H (2008), Yu Q (2018)	3
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
TRAF6	0	LAT	0	affinity chromatography technology, biochemical, affinity chromatography technology	Xie JJ (2013), Xie JJ (2013), Yang Y (2015)	3
UBASH3B	4	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
PTPN6	0	SYK	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Dustin LB (1999), Dustin LB (1999)	3
NCK1	0	CD3E	0	pull down	Gil D (2002)	1
SYK	3	PIK3R2	3	two hybrid	Moon KD (2005)	1
GRB2	2	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid	Lewitzky M (2001), Robinson A (1996), Erdreich-Epstein A (1999), Hendricks-Taylor LR (1997), Asada H (1999), Bandyopadhyay S (2010), Chu J (1998), Berry DM (2002), Brehme M (2009), Rolland T (2014)	10
PTK2B	6	LYN	2	affinity chromatography technology	Yamasaki M (2001)	1
SRC	2	PXN	1	pull down	Angers-Loustau A (1999)	1
SYK	3	SP1	0	affinity chromatography technology	Wang L (2005)	1
UBASH3B	4	CBL	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kowanetz K (2004), Kowanetz K (2004), Raguz J (2007), Hoeller D (2006), Peruzzi G (2007), Brehme M (2009)	6
NCK1	0	ERBB3	3	unspecified method	Jones RB (2006)	1
CD22	3	PTPN6	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blasioli J (1999), Blasioli J (1999), Otipoby KL (2001), Greer SF (1999), Law CL (1996), Adachi T (2001)	6
GRAP2	0	ERBB2	6	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
GRB2	2	PXN	1	pull down	Angers-Loustau A (1999)	1
NEDD4	2	SRC	2	affinity chromatography technology, pull down, enzymatic study	Persaud A (2014), Persaud A (2014), Persaud A (2014)	3
FLNA	10	SYK	3	imaging technique	Justa-Schuch D (2016)	1
SYK	3	NCK1	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
ITGA4	4	PIK3R2	3	affinity chromatography technology	Byron A (2012)	1
PTPN6	0	BLNK	2	affinity chromatography technology	Adachi T (2001)	1
RHOU	0	PXN	1	pull down	Dart AE (2015)	1
TLR3	2	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang M (2011), Jiang Z (2003), Jiang Z (2003), Cusson-Hermance N (2005), Zinngrebe J (2016)	5
PTK2B	6	ERBB2	6	affinity chromatography technology, imaging technique	Zrihan-Licht S (2000), Chen TC (2014)	2
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
EGFR	5	TUBG1	2	affinity chromatography technology	Tong J (2014)	1
MYD88	1	MAP3K7	2	genetic interference	Fitzgerald KA (2001)	1
STAT3	0	PIK3R2	3	two hybrid	Grossmann A (2015)	1
HDAC6	0	MYD88	1	affinity chromatography technology, affinity chromatography technology	Into T (2010), Into T (2010)	2
LYN	2	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Taher TE (2002), Dombrosky-Ferlan PM (1997), Kaabeche K (2004), Wu J (2008), Tanaka S (1995), Marcilla A (1995)	6
SH2D2A	2	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
PTK2	2	APP	1	pull down	Olah J (2011)	1
BTK	1	TLR4	5	two hybrid	Jefferies CA (2003)	1
TICAM1	3	TLR4	5	affinity chromatography technology, affinity chromatography technology	Piao W (2009), Hu YH (2015)	2
FCGR3A	0	APP	1	pull down	Olah J (2011)	1
TRAIP	0	TRAF6	0	affinity chromatography technology	Besse A (2007)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
TNFRSF1A	3	FYN	1	biochemical	Legler DF (2003)	1
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
NCK1	0	TUBA1A	13	affinity chromatography technology	Jeong DG (2007)	1
BTK	1	APP	1	pull down	Olah J (2011)	1
EGFR	5	CTTN	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
SH2D2A	2	PIK3R1	6	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
SRC	2	ITGB3	6	enzymatic study	Kirk RI (2000)	1
PLCG1	6	BLNK	2	affinity chromatography technology	Yasuda T (2000)	1
GRB2	2	INPP5D	2	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavanaugh WM (1996), Kavanaugh WM (1996), de Castro RO (2012), Ho JM (2002)	4
GRASP	1	GRM1	4	affinity chromatography technology	Hirose M (2004)	1
PTPN6	0	LCK	0	enzymatic study, enzymatic study, pull down	Yu CL (2000), Chiang GG (2001), Lorenz U (1994)	3
CTTN	1	PXN	1	affinity chromatography technology, imaging technique	Onodera Y (2005), Chen TC (2014)	2
EPOR	3	CBL	7	affinity chromatography technology	Wakioka T (1999)	1
FYN	1	PAG1	5	pull down, affinity chromatography technology	Brdicka T (2000), Brdicka T (2000)	2
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
TBK1	1	SRC	2	affinity chromatography technology	Johnsen IB (2009)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
FYN	1	GRM1	4	affinity chromatography technology, affinity chromatography technology	Hirose M (2004), Hirose M (2004)	2
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
TLR4	5	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang M (2011), Floreani NA (2010), Floreani NA (2010)	3
CD22	3	PLCG1	6	affinity chromatography technology	Law CL (1996)	1
NEDD4	2	ERBB4	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zeng F (2009), Zeng F (2009), Zeng F (2009)	3
EGFR	5	TUBA1A	13	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
TNFRSF1A	3	PIK3R1	6	affinity chromatography technology	Pincheira R (2008)	1
ERBB4	5	CBL	7	affinity chromatography technology	Kiuchi T (2014)	1
VAV1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bertagnolo V (1998), Bertagnolo V (1998), Bertagnolo V (1998), Shigematsu H (1997), Shigematsu H (1997), Shigematsu H (1997)	6
VCAM1	2	ITGA4	4	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Byron A (2012)	2
NEDD4	2	FYN	1	enzymatic study, pull down	Persaud A (2009), Persaud A (2009)	2
LYN	2	CD72	2	enzymatic study	Adachi T (1998)	1
TLR9	2	SRC	2	affinity chromatography technology	Yang M (2011)	1
CBLB	3	MS4A2	1	biochemical	Qu X (2005)	1
TRAF3	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kayagaki N (2007), Mankouri J (2010), Mankouri J (2010), Tzieply N (2012), Wang Y (2012), Ng MH (2011), Charoenthongtrakul S (2013), van Zuylen WJ (2012), van Zuylen WJ (2012), Karim R (2013), Chen X (2014), Peng Y (2014), Wang S (2013), Zhou Y (2016), Cai B (2017), Fang R (2017), Fang R (2017)	17
TNFRSF1A	3	CBL	7	affinity chromatography technology	Narita T (2005)	1
SYK	3	CD3E	0	pull down	Bu JY (1995)	1
FLNA	10	ITGB3	6	two hybrid	van der Flier A (2002)	1
CD19	3	SYK	3	affinity chromatography technology	Carter RH (1997)	1
VCAM1	2	RPS10	0	affinity chromatography technology	Humphries JD (2009)	1
ERBB3	3	NEDD4	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Huang Z (2014), Huang Z (2014), Huang Z (2014), Verma N (2017)	4
BLNK	2	CD79A	2	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Engels N (2001), Kabak S (2002), Kabak S (2002), Oellerich T (2011)	4
PTK2B	6	ITGB2	4	affinity chromatography technology	Miura Y (2000)	1
TRAF3	1	SRC	2	affinity chromatography technology, affinity chromatography technology	Wong BR (1999), Johnsen IB (2009)	2
VAV1	2	EPOR	3	affinity chromatography technology	Shigematsu H (1997)	1
NEDD4	2	RPS6KB1	1	enzymatic study	Persaud A (2009)	1
IL17RA	3	HDAC3	5	affinity chromatography technology	Huttlin EL (2017)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
GRB2	2	TNFRSF1A	3	affinity chromatography technology, affinity chromatography technology	Hildt E (1999), Kurada BR (2009)	2
SRC	2	PTPN6	0	enzymatic study	Frank C (2004)	1
LYN	2	PAG1	5	pull down	Brdicka T (2000)	1
FYN	1	VAV1	2	affinity chromatography technology, two hybrid	Michel F (1998), Tartare-Deckert S (2001)	2
CBL	7	SLA	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang J (1999), Myers MD (2006), Sirvent A (2008), Swaminathan G (2007)	4
EGFR	5	LAT	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
LYN	2	EPOR	3	pull down, affinity chromatography technology, affinity chromatography technology	Chin H (1998), Chin H (1998), Chin H (1998)	3
SYK	3	MAP3K7	2	affinity chromatography technology	Lin YC (2013)	1
FYN	1	LAT	0	enzymatic study	Jiang Y (2007)	1
LYN	2	CD22	3	enzymatic study, affinity chromatography technology	Poe JC (2000), Greer SF (1999)	2
ITGB3	6	ITGA4	4	imaging technique	Moon HE (2015)	1
STAT3	0	FGR	1	pull down, two hybrid	Schreiner SJ (2002), Wang J (2011)	2
BTK	1	LYN	2	pull down	Cheng G (1994)	1
ITGA4	4	FLNA	10	affinity chromatography technology	Byron A (2012)	1
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
PTPRO	3	APP	1	pull down	Olah J (2011)	1
TNFRSF1A	3	TRAF6	0	affinity chromatography technology	Chang YL (2014)	1
CRKL	1	INPP5D	2	pull down, affinity chromatography technology	Arai A (2001), Arai A (2001)	2
LCP2	0	PLCG1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Yablonski D (2001), Yablonski D (2001), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
MYD88	1	TRAF3	1	affinity chromatography technology	Zhou J (2011)	1
CRKL	1	BLNK	2	affinity chromatography technology	Engels N (2001)	1
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
SYK	3	VAV1	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Deckert M (1996), Deckert M (1996), Deckert M (1996), Song JS (1996), Bertagnolo V (2001), Bertagnolo V (2001), Tartare-Deckert S (2001)	7
SYK	3	SH3BP2	4	two hybrid, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
EGFR	5	HGS	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Umebayashi K (2008), Morino C (2004), Meijer IM (2013), Sun Y (2013), Ali N (2013), Tan X (2015)	6
SH2D2A	2	FAM46A	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
TNFRSF1A	3	SRC	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Narita T (2005), Pincheira R (2008), Darnay BG (1997)	3
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
GRAP2	0	LAT	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Liu SK (1999), Liu SK (1999), Liu SK (1999), Asada H (1999)	4
FYN	1	GRASP	1	enzymatic study	Hirose M (2004)	1
SYK	3	TYROBP	0	pull down	McVicar DW (1998)	1
SH3BP2	4	VAV1	2	affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology	Jevremovic D (2001), Jevremovic D (2001), Le Bras S (2007), GuezGuez A (2010)	4
SYK	3	LYN	2	affinity chromatography technology, pull down	Sidorenko SP (1995), Sidorenko SP (1995)	2
TRAF6	0	FYN	1	pull down	Liu A (2012)	1
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
TUBG1	2	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
VAV1	2	TUBB	3	affinity chromatography technology, affinity chromatography technology	Huby RD (1995), Fernandez JA (1999)	2
GRB2	2	SYK	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Saci A (2002), de Castro RO (2012), de Castro RO (2012)	4
SYK	3	LCP2	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
SYK	3	FCGR1A	0	imaging technique	Chen TC (2014)	1
PTK2B	6	MAPT	1	enzymatic study	Virdee K (2007)	1
STAT3	0	SYK	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
CBL	7	VAV2	6	affinity chromatography technology, affinity chromatography technology, pull down	Duan L (2011), Duan L (2011), Tartare-Deckert S (2001)	3
BLNK	2	PLCG2	11	affinity chromatography technology, affinity chromatography technology	Oellerich T (2011), Oellerich T (2011)	2
CBLB	3	UBASH3B	4	two hybrid	Rolland T (2014)	1
EGFR	5	LCP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
ERBB2	6	SLA	2	unspecified method	Jones RB (2006)	1
SYK	3	APP	1	pull down	Olah J (2011)	1
ERBB4	5	ERBB2	6	affinity chromatography technology	Huang YZ (2000)	1
LYN	2	RPS6KB2	3	enzymatic study	Rebholz H (2006)	1
EGFR	5	MAPT	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PTPN6	0	EPOR	3	affinity chromatography technology, pull down	Klingmueller U (1995), Klingmueller U (1995)	2
PTPN6	0	LCP2	0	pull down, pull down, affinity chromatography technology	Binstadt BA (1998), Mizuno K (1996), Mizuno K (1996)	3
TERF1	1	SYK	3	two hybrid	Lee OH (2011)	1
FCGR2A	0	PIK3R1	6	affinity chromatography technology, pull down	Chacko GW (1996), Ibarrola I (1997)	2
SYK	3	PAG1	5	pull down	Brdicka T (2000)	1
EPOR	3	INPP5D	2	protein complementation assay	Montoye T (2005)	1
VAV2	6	CD19	3	pull down, affinity chromatography technology	Doody GM (2000), Doody GM (2000)	2
RPS6KB1	1	MAPT	1	enzymatic study	Virdee K (2007)	1
TRAF3	1	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Wang PX (2016), Wang PX (2016), Wang PX (2016)	3
GRASP	1	SYK	3	affinity chromatography technology	Hirose M (2004)	1
PLCG1	6	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	BLNK	2	unspecified method	Jones RB (2006)	1
ERBB3	3	CRKL	1	unspecified method	Jones RB (2006)	1
IL17RA	3	MAP3K7	2	affinity chromatography technology	Qian Y (2007)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
ERBB4	5	NCK1	0	affinity chromatography technology	Schulze WX (2006)	1
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
PXN	1	LCK	0	affinity chromatography technology	Ostergaard HL (1998)	1
GRB2	2	PAG1	5	pull down	Brdicka T (2000)	1
CALM1	0	CBL	7	affinity chromatography technology, affinity chromatography technology	Singh VK (2012), Singh VK (2012)	2
SYK	3	IL17RA	3	affinity chromatography technology	Wu NL (2014)	1
TICAM1	3	SYK	3	affinity chromatography technology	Lin YC (2013)	1
GRAP2	0	CBL	7	biochemical, affinity chromatography technology, two hybrid	Yankee TM (2003), Yankee TM (2003), Grossmann A (2015)	3
SIRPB1	6	SYK	3	affinity chromatography technology	Tomasello E (2000)	1
LAT	0	PLCG2	11	fluorescent resonance energy transfe, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
TLR3	2	PIK3R1	6	affinity chromatography technology	Sarkar SN (2004)	1
SYK	3	SH2D2A	2	two hybrid	Rolland T (2014)	1
LCP2	0	PIK3R1	6	two hybrid, affinity chromatography technology	Shim EK (2004), Shim EK (2004)	2
EGFR	5	CALM1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, pull down	Li H (2004), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Aifa S (2002)	5
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
INPP5D	2	CBL	7	affinity chromatography technology	Bao M (2012)	1
TRIM15	0	PXN	1	affinity chromatography technology, affinity chromatography technology, pull down	Uchil PD (2014), Uchil PD (2014), Uchil PD (2014)	3
PTPN6	0	ERBB4	5	enzymatic study, two hybrid	Yao Z (2017), Yao Z (2017)	2
SYK	3	FCER1G	0	pull down	Kihara H (1994)	1
TRAF6	0	CBLB	3	affinity chromatography technology	Qiao G (2007)	1
FCGR2A	0	SYK	3	pull down, affinity chromatography technology	Ibarrola I (1997), Kim MK (2001)	2
TLR4	5	HGS	5	affinity chromatography technology, affinity chromatography technology	Husebye H (2006), Husebye H (2006)	2
BTK	1	RPS6KB2	3	enzymatic study	Rebholz H (2006)	1
TUBB	3	APP	1	pull down	Olah J (2011)	1
SYK	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down	Wang L (2005), Wang L (2005), Wang L (2005)	3
EGFR	5	SYK	3	unspecified method	Jones RB (2006)	1
PTK2B	6	VAV1	2	pull down	Katagiri T (2000)	1
PXN	1	TUBG1	2	pull down	Brown MC (2002)	1
CBL	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Erdreich-Epstein A (1999), Chu J (1998), Shen M (2009)	4
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
CRKL	1	EPOR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Chin H (1997), Arai A (2001), Arai A (2001), Barber DL (1997)	4
TNFRSF1A	3	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahmad R (2007), Fan YH (2011), Cusson-Hermance N (2005), Blonska M (2005), Mitsuhashi S (2008)	5
SYK	3	FGR	1	affinity chromatography technology, two hybrid	Vines CM (2001), Moon KD (2005)	2
LYN	2	HCLS1	0	affinity chromatography technology	Yamanashi Y (1993)	1
FCGR1A	0	LAT	0	affinity chromatography technology	Tridandapani S (2000)	1
MS4A2	1	APP	1	pull down	Olah J (2011)	1
10748	0	TYROBP	0	affinity chromatography technology	McVicar DW (1998)	1
HDAC6	0	TUBA1A	13	enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Matsuyama A (2002), Hubbert C (2002), Zhao Z (2010), Zhao Z (2010), New M (2013)	6
GRM1	4	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
BTK	1	CBLB	3	affinity chromatography technology	Yasuda T (2002)	1
TRIM15	0	CTTN	1	affinity chromatography technology, protein complementation assay	Lee OH (2015), Lee OH (2015)	2
MAP3K7	2	HGS	5	pull down	Sasaki Y (2001)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
SP1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Padova M (2003), Singh J (2002), Zhang Y (2002), Sun JM (2002), Gao J (2009), Shon JK (2009), Mottet D (2009), Goto T (2006), Hung JJ (2006), Lagger G (2003), Choi HS (2002), Choi HS (2002), Kang JE (2005), Kang JE (2005), Kang JE (2005), Gan Y (2005), Gan Y (2005), Duan H (2005), Varshochi R (2005), Varshochi R (2005), Plaisance V (2005), Walker GE (2001), Walker GE (2001), Ammanamanchi S (2004), Doetzlhofer A (1999), Sekhavat A (2007), Liu T (2007), Enya K (2008), Liu S (2010), Leclerc GJ (2010), Leclerc GJ (2010), Wong CY (2011), Schnur N (2007)	33
ERBB3	3	VAV1	2	unspecified method	Jones RB (2006)	1
SRC	2	MAPT	1	enzymatic study	Bhaskar K (2005)	1
SYK	3	LAT	0	enzymatic study	Paz PE (2001)	1
PXN	1	ITGA4	4	pull down, pull down	Han J (2001), Liu S (2002)	2
SIT1	1	LCK	0	affinity chromatography technology	Marie-Cardine A (1999)	1
SP1	0	CALM1	0	affinity chromatography technology	Chuang JY (2012)	1
GRB2	2	CTTN	1	affinity chromatography technology	Brehme M (2009)	1
SYK	3	SEC23B	0	affinity chromatography technology	de Castro RO (2012)	1
LCP2	0	LYN	2	affinity chromatography technology, pull down	Gross BS (1999), Gross BS (1999)	2
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
SRC	2	HDAC3	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Longworth MS (2006), Longworth MS (2006), Longworth MS (2006), Matteucci E (2007)	4
FYN	1	PIK3R2	3	pull down	Gout I (1992)	1
LAT	0	LCP2	0	affinity chromatography technology	Xie JJ (2013)	1
EGFR	5	TBK1	1	affinity chromatography technology	Tong J (2014)	1
NEDD4	2	EGFR	5	enzymatic study, pull down	Persaud A (2009), Persaud A (2009)	2
TLR3	2	MYD88	1	pull down	Doyle SE (2003)	1
CBLB	3	CRKL	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Elly C (1999), Elly C (1999), Grossmann A (2015)	3
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
SYK	3	HDAC3	5	affinity chromatography technology, pull down	Wang L (2005), Wang L (2005)	2
CD3E	0	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
TERF1	1	HCLS1	0	two hybrid	Lee OH (2011)	1
TICAM1	3	TLR3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang Z (2004), Hu YH (2015), Zinngrebe J (2016)	3
NCK1	0	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
HDAC3	5	TUBA1A	13	biochemical	Havugimana PC (2012)	1
TRIM15	0	PTK2	2	protein complementation assay	Lee OH (2015)	1
BTK	1	VAV1	2	affinity chromatography technology	Guinamard R (1997)	1
GRB2	2	HGS	5	affinity chromatography technology	Bisson N (2011)	1
EPOR	3	PLCG1	6	protein complementation assay	Montoye T (2005)	1
LAT	0	CD3E	0	affinity chromatography technology	Munoz P (2003)	1
UBASH3B	4	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), Li J (2013), Li J (2013)	3
PLCG1	6	SYK	3	affinity chromatography technology	Sidorenko SP (1995)	1
IL17RA	3	TRAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rong Z (2007), Rong Z (2007), Qian Y (2007)	3
HGS	5	TUBB	3	pull down	Pridgeon JW (2009)	1
BLNK	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fu C (1998), Engels N (2001), Fusaki N (2000), Wienands J (1998), Oellerich T (2011), Oellerich T (2011)	6
PLCG2	11	LYN	2	affinity chromatography technology, pull down, affinity chromatography technology	Pleiman CM (1993), Pleiman CM (1993), Guo B (2000)	3
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
HDAC6	0	ERBB3	3	protein complementation assay	Deribe YL (2009)	1
PIK3R2	3	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
BTK	1	FYN	1	pull down	Cheng G (1994)	1
STAT3	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Zhang Q (2005), Yuan ZL (2005), Gupta M (2011), Zhi Y (2012), Zhi Y (2012)	5
SH3BP2	4	GRB2	2	pull down	Deckert M (1998)	1
HDAC9	7	HDAC4	10	pull down	Petrie K (2003)	1
MEGF10	3	SYK	3	affinity chromatography technology	Scheib JL (2012)	1
SYK	3	CTTN	1	affinity chromatography technology, imaging technique	Maruyama S (1996), Chen TC (2014)	2
CBLB	3	SYK	3	affinity chromatography technology, enzymatic study	Elly C (1999), Wirnsberger G (2016)	2
SYK	3	HDAC4	10	pull down	Wang L (2005)	1