PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
XRCC6	3	ORC2	0	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
HSP90AA1	7	TERF1	1	affinity chromatography technology	Hein MY (2015)	1
EP300	36	MRE11	3	affinity chromatography technology	Jung SY (2005)	1
EP300	36	TERF2	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Her YR (2013), Her YR (2013), Her YR (2013), Her YR (2013)	4
TERF2	2	TERF2	2	affinity chromatography technology, two hybrid, pull down	Liu D (2004), Lee OH (2011), Sommers JA (2014)	3
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
WRN	6	POT1	2	genetic interference	Takahashi K (2010)	1
BRCA1	7	RAD50	3	biochemical, biochemical, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Greenberg RA (2006), Chen L (2008), Hill SJ (2014), Acharya S (2014)	10
XRCC5	5	TOP2A	2	affinity chromatography technology	Matheos D (2002)	1
TERF2IP	1	POT1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu D (2004), Ye JZ (2004), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	5
EP300	36	PIAS1	4	pull down, affinity chromatography technology	Ledsaak M (2016), Ledsaak M (2016)	2
BRCA1	7	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Acharya S (2014), Ertych N (2016)	3
XRCC6	3	TINF2	1	affinity chromatography technology	Hein MY (2015)	1
BLM	2	WRN	6	affinity chromatography technology, pull down	von Kobbe C (2002), von Kobbe C (2002)	2
BLM	2	TERF2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Opresko PL (2002), Bhattacharyya S (2009), Lillard-Wetherell K (2004), Lillard-Wetherell K (2004)	4
FBL	1	PRMT1	3	affinity chromatography technology, enzymatic study	Yanagida M (2004), Miranda TB (2005)	2
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
MRE11	3	PRMT1	3	affinity chromatography technology	Dery U (2008)	1
ATM	9	TERF2	2	affinity chromatography technology, pull down	Karlseder J (2004), Karlseder J (2004)	2
TINF2	1	TERF1	1	affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu D (2004), Stelzl U (2005), Kim SH (1999), Kim SH (1999), Giannone RJ (2010), Zhu Q (2009), Zhu Q (2009), Zhu Q (2009), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Ye JZ (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Tan R (2017)	18
TERF2	2	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	OConnor MS (2004), OConnor MS (2004), OConnor MS (2004), Li B (2000), Zhu XD (2000), Zhu XD (2000), Chen Y (2011), Chen Y (2011), Chen Y (2011), Chen Y (2011), Liu D (2004), Liu D (2004), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Her YR (2009), Havugimana PC (2012), Her YR (2013), Wan C (2015), Hein MY (2015), Her J (2015), Arat N Oe (2012), Li JS (2017), Jeong YY (2016), Ilic A (2017), Ilic A (2017)	28
POT1	2	TINF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ye JZ (2004), Ye JZ (2004), Liu D (2004), Loayza D (2003), Loayza D (2003), Giannone RJ (2010), Liu D (2004), Liu D (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	14
ATM	9	MRE11	3	unspecified method, biochemical, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Falck J (2005)	3
TINF2	1	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu D (2004), Liu D (2004), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
DCLRE1B	2	TINF2	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
PRPF40A	5	TERF2IP	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TERF2	2	ORC1	3	pull down, affinity chromatography technology	Tatsumi Y (2008), Tatsumi Y (2008)	2
BLM	2	TEP1	10	affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009)	2
MRE11	3	XRCC6	3	two hybrid, pull down, affinity chromatography technology, biochemical	Goedecke W (1999), Goedecke W (1999), Goedecke W (1999), Wan C (2015)	4
TERF2	2	TOP2A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009), Bhattacharyya S (2009)	3
CCDC106	1	TERF2IP	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIAH1	2	PIAS1	4	two hybrid, pull down, affinity chromatography technology	Depaux A (2007), Depaux A (2007), Lee JH (2016)	3
XRCC6	3	TERF2	2	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song K (2000), Song K (2000), Song K (2000), Lee OH (2011), Hein MY (2015)	5
TERF2	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009), Bhattacharyya S (2009)	3
WRN	6	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Orren DK (2001), Li B (2004), Li B (2004), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Partridge JJ (2003), Partridge JJ (2003), Hein MY (2015)	14
PRMT1	3	TERF1	1	affinity chromatography technology	Mitchell TR (2009)	1
TERF2	2	DDX39A	3	two hybrid, affinity chromatography technology, affinity chromatography technology	Lee OH (2011), Huttlin EL (2015), Huttlin EL (2017)	3
DCLRE1B	2	RAD50	3	affinity chromatography technology, affinity chromatography technology	Bae JB (2008), Bae JB (2008)	2
TERF2IP	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), OConnor MS (2004), Liu D (2004)	3
MUS81	1	WRN	6	genetic interference	Vizeacoumar FJ (2013)	1
XRCC5	5	NBN	1	affinity chromatography technology	Falck J (2005)	1
PRMT1	3	TERF2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Mitchell TR (2009), Mitchell TR (2009), Mitchell TR (2009)	3
BRCA1	7	DDX39A	3	affinity chromatography technology	Hill SJ (2014)	1
DCLRE1B	2	MRE11	3	affinity chromatography technology	Bae JB (2008)	1
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
BRCA1	7	TERF2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009), Hill SJ (2014)	3
ORC1	3	ORC2	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Fujita M (2002), Vashee S (2001), Vashee S (2001), Mendez J (2002), Mendez J (2002), Ramachandran N (2004), Vermeulen M (2010), Hein MY (2015), Hein MY (2015)	11
TADA2B	3	TERF2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NBN	1	TERF2IP	1	biochemical	Havugimana PC (2012)	1
TERF2IP	1	XRCC6	3	affinity chromatography technology, two hybrid, affinity chromatography technology	OConnor MS (2004), Lee OH (2011), Hein MY (2015)	3
DCLRE1B	2	TERF2IP	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
MRE11	3	BLM	2	biochemical	Wang Y (2000)	1
TERF1	1	ATM	9	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down	Kishi S (2001), Kishi S (2001), Kishi S (2001), Takai H (2007), Karlseder J (2004)	5
TERF1	1	DDX39A	3	two hybrid	Lee OH (2011)	1
TERF2	2	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Zhu XD (2000), Zhu XD (2000), Li B (2008), Havugimana PC (2012)	4
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
ATM	9	BRCA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Gatei M (2000), Gatei M (2000), Kim ST (1999), Cortez D (1999), Cortez D (1999), Tibbetts RS (2000), Wang Y (2000), Mu JJ (2007), Tsai WB (2008), Gatei M (2000), Gatei M (2000), Gatei M (2000)	12
TINF2	1	MRE11	3	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	TERF1	1	affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009)	2
BLM	2	TERF1	1	pull down	Lillard-Wetherell K (2004)	1
FBL	1	TERF2IP	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TADA2B	3	TERF2IP	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MUS81	1	TERF2	2	affinity chromatography technology, affinity chromatography technology	Zeng S (2009), Zeng S (2009)	2
TERF2IP	1	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), OConnor MS (2004), Liu D (2004), Havugimana PC (2012)	4
TERF2IP	1	MRE11	3	affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), Liu D (2004), Havugimana PC (2012)	3
NBN	1	RAD50	3	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Desai-Mehta A (2001), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Greenberg RA (2006), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015)	17
NBN	1	BLM	2	biochemical	Wang Y (2000)	1
ATM	9	WRN	6	unspecified method	Kim ST (1999)	1
SLX4	6	MUS81	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Ghosal G (2012), Kim Y (2011), Munoz IM (2009), Munoz IM (2009), Fekairi S (2009), Kim Y (2013), Wilson JS (2013), Wan B (2013), Wan B (2013), Wan B (2013), Rolland T (2014), Yu H (2011), Nair N (2014), Nair N (2014), Nair N (2014), Ouyang J (2015), Huttlin EL (2017), Schuster B (2013), Bogliolo M (2013)	21
BLM	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009)	2
TINF2	1	WRN	6	affinity chromatography technology	Hein MY (2015)	1
XRCC5	5	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wei L (2008), Wei L (2008), Jiang G (2013), Jiang G (2013), Jiang G (2013), Ertych N (2016)	6
XRCC5	5	ATM	9	pull down	Falck J (2005)	1
PRPF40A	5	PIAS1	4	two hybrid	Colland F (2004)	1
NBN	1	TERF1	1	two hybrid	Wu G (2000)	1
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
MRE11	3	RAD50	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Chiba N (2001), Chiba N (2001), Dolganov GM (1996), Dolganov GM (1996), Trujillo KM (1998), Goedecke W (1999), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Cho YW (2007), Greenberg RA (2006), Alt JR (2005), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Wijnhoven P (2015), Boldt K (2016), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015), Nicholson J (2017)	25
PRMT1	3	BRCA1	7	enzymatic study, pull down, affinity chromatography technology	Guendel I (2010), Guendel I (2010), Ertych N (2016)	3
TERF1	1	TERF2IP	1	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Huttlin EL (2015), Hein MY (2015)	6
EP300	36	RAD50	3	affinity chromatography technology, pull down	Jung SY (2005), Karmakar S (2010)	2
DCLRE1B	2	POT1	2	affinity chromatography technology	Hein MY (2015)	1
TERF2	2	SIAH1	2	pull down, enzymatic study	Fujita K (2010), Fujita K (2010)	2
DCLRE1B	2	TERF1	1	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	PIAS1	4	imaging technique, enzymatic study, imaging technique	Galanty Y (2009), Morris JR (2009), Morris JR (2009)	3
TERF2	2	UCHL1	1	affinity chromatography technology, imaging technique	Ilic A (2017), Ilic A (2017)	2
EP300	36	XRCC6	3	enzymatic study	Cohen HY (2004)	1
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
TERF2	2	WRN	6	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Li B (2008)	6
TERF1	1	XRCC5	5	affinity chromatography technology	Giannone RJ (2010)	1
TERF2	2	TEP1	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009), Bhattacharyya S (2009)	3
TERF2	2	REST	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Zhang P (2008), Zhang P (2008), Zhang P (2008)	3
TERF2	2	POT1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Giannone RJ (2010), Giannone RJ (2010), Liu D (2004), Liu D (2004), Liu D (2004), Hein MY (2015), Huttlin EL (2017)	7
TINF2	1	UCHL1	1	two hybrid	Lee OH (2011)	1
XRCC5	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Zhang Z (2017), Zhang Z (2017)	2
XRCC5	5	ORC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matheos D (2002), Sibani S (2005), Sibani S (2005)	3
WRN	6	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng WH (2005), Kobayashi J (2010), Kobayashi J (2010)	3
BRCA1	7	TOP2A	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lou Z (2005), Lou Z (2005), Lou Z (2005), Hill SJ (2014)	4
TERF1	1	EP300	36	affinity chromatography technology	Her YR (2013)	1
TEX264	0	TERF2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RNF4	1	TERF2	2	affinity chromatography technology, affinity chromatography technology, pull down	Her J (2015), Her J (2015), Her J (2015)	3
POT1	2	TERF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loayza D (2003), Giannone RJ (2010), Giannone RJ (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
BRCA1	7	FBL	1	affinity chromatography technology	Ertych N (2016)	1
TINF2	1	TERF2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, far western blotting, imaging technique, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu D (2004), Giannone RJ (2010), Liu D (2004), Liu D (2004), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Her YR (2013), Her YR (2013), Hein MY (2015), Huttlin EL (2017)	15
DCLRE1B	2	TERF2	2	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Freibaum BD (2006), Chen Y (2011), Lenain C (2006), Lenain C (2006), Hein MY (2015)	5
TERF2	2	NBN	1	affinity chromatography technology, affinity chromatography technology, biochemical	Zhu XD (2000), Zhu XD (2000), Havugimana PC (2012)	3
AKTIP	3	TERF1	1	pull down, affinity chromatography technology	Burla R (2015), Burla R (2015)	2
EP300	36	NBN	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Jung SY (2005), Jang ER (2011), Jang ER (2011)	3
TERF2	2	TERF1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Giannone RJ (2010), Ye JZ (2004), Ye JZ (2004)	3
RAD50	3	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Acharya S (2014), Acharya S (2014)	3
TERF2	2	PIAS1	4	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Her J (2015), Her J (2015), Her J (2015), Her J (2015)	4
SLX4	6	TERF2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, imaging technique, x-ray crystallography, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Wilson JS (2013), Wilson JS (2013), Wilson JS (2013), Wan B (2013), Wan B (2013), Wan B (2013), Wan B (2013), Wan B (2013), Ouyang J (2015)	11
UCHL1	1	HSP90AA1	7	affinity chromatography technology, pull down	Kabuta T (2008), Kabuta T (2008)	2
WRN	6	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Li B (2004), Li B (2004), Hein MY (2015), Huttlin EL (2017)	10
ATM	9	NBN	1	unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Cariveau MJ (2007), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Wu J (2012), Wei F (2015)	12
SLX4	6	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Svendsen JM (2009), Svendsen JM (2009), Ghosal G (2012)	3
EP300	36	ORC2	0	pull down	Karmakar S (2010)	1
PRPF40A	5	XRCC6	3	pull down	Ingham RJ (2005)	1
FBL	1	TERF2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SLX4	6	MRE11	3	affinity chromatography technology	Ouyang J (2015)	1
EP300	36	PRMT1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Hassa PO (2008), Lai Y (2017), Lai Y (2017)	3
TERF2	2	ORC2	0	pull down, affinity chromatography technology	Tatsumi Y (2008), Tatsumi Y (2008)	2
RAD50	3	ATM	9	biochemical	Wang Y (2000)	1
SLX4	6	DCLRE1B	2	affinity chromatography technology	Salewsky B (2012)	1
ORC2	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Matsuoka S (2007), Hill SJ (2014)	2
TERF2IP	1	UCHL1	1	two hybrid, imaging technique, biochemical	Lee OH (2011), Ilic A (2017), Ilic A (2017)	3
TERF2	2	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	OConnor MS (2004), Zhu XD (2000), Zhu XD (2000), Li B (2008), Havugimana PC (2012)	5
AKTIP	3	TERF2	2	pull down, affinity chromatography technology	Burla R (2015), Burla R (2015)	2
BRCA1	7	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
XRCC6	3	POT1	2	affinity chromatography technology	Hein MY (2015)	1
BLM	2	TOP2A	2	affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009)	2
TERF2IP	1	DDX39A	3	two hybrid	Lee OH (2011)	1
CCDC106	1	TERF2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ATM	9	BLM	2	biochemical, pull down, affinity chromatography technology	Wang Y (2000), Beamish H (2002), Beamish H (2002)	3
SLX4	6	NBN	1	affinity chromatography technology	Ouyang J (2015)	1
TERF2	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), Giannone RJ (2010)	2
PRPF40A	5	TERF2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TERF1	1	RAD50	3	affinity chromatography technology	Giannone RJ (2010)	1
XRCC5	5	ORC1	3	affinity chromatography technology	Matheos D (2002)	1