PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NR2C1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
RCOR1	0	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2002), You A (2001), You A (2001), Gocke CB (2008), Battaglioli E (2002), Gu H (2005), Pflum MK (2001), Humphrey GW (2001), Humphrey GW (2001), Humphrey GW (2001), Cetinkaya C (2007), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	15
NR2C1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
KDM1A	2	RBBP7	1	affinity chromatography technology	Li Q (2011)	1
HDAC2	1	ESR1	0	affinity chromatography technology, affinity chromatography technology	Itoh Y (2007), Tarallo R (2011)	2
KDM1A	2	MTA1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wang Y (2009), Wang Y (2009), Cui S (2011), Cui S (2011)	4
HDAC1	4	ESR1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Kawai H (2003), Kawai H (2003), Varshochi R (2005), Varshochi R (2005), Kurtev V (2004), Liu XF (2004), Itoh Y (2007), Tarallo R (2011), Yoshimaru T (2013)	9
NR2C1	0	POLD3	0	affinity chromatography technology	Cui S (2011)	1
DNMT1	5	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Cui S (2011), Cui S (2011), Cai Y (2014), Cai Y (2014), Cai Y (2014), Cai Y (2014)	6
SMARCA4	19	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Sif S (2001), Qiu Z (2008), Xu Z (2006), Pal S (2003), Battaglioli E (2002), Tando T (2010), Hang CT (2010), Shen JP (2017)	8
MTA2	1	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Zhang Y (1998), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Quan J (2014), Wan C (2015)	8
SFPQ	2	PSPC1	2	affinity chromatography technology	Huttlin EL (2017)	1
HDAC1	4	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yao YL (2003), Yao YL (2003), Yao YL (2003), Mazumdar A (2001), Mazumdar A (2001), Yoo YG (2006), Liu XF (2004), Khaleque MA (2008), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Millard CJ (2016), Millard CJ (2016)	21
NR2C1	0	RBBP7	1	affinity chromatography technology	Cui S (2011)	1
TRIM28	1	SIN3A	13	pull down	Nomura T (2004)	1
AR	3	HDAC1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gaughan L (2002), Gaughan L (2002), Gaughan L (2005), Gaughan L (2005), Gobinet J (2005), Peche LY (2015)	6
NR2C1	0	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
RBBP4	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Hakimi MA (2003), Zhang Y (2002), Tong JK (1998), Sun JM (2007), Sun JM (2007), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Wan C (2015), Hauri S (2016)	14
NR2C1	0	NONO	3	affinity chromatography technology	Cui S (2011)	1
AR	3	NR2C2	0	two hybrid, pull down	Lee YF (1999), Lee YF (1999)	2
AR	3	HDAC4	10	pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Franco PJ (2003), Yang Y (2011), Yang Y (2011), Yang Y (2011), Yang Y (2011), Yang Y (2011)	6
DNMT1	5	KDM1A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Clements EG (2012), Clements EG (2012), Cui S (2011), Cui S (2011)	4
MTA1	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Mazumdar A (2001), Mazumdar A (2001), Mazumdar A (2001), Li DQ (2010), Yan C (2003), Balasenthil S (2007), Ohshiro K (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	16
MTA1	3	POLD3	0	affinity chromatography technology	Cui S (2011)	1
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
HDAC1	4	TRIM28	1	affinity chromatography technology, affinity chromatography technology, biochemical	Allouch A (2011), Chen L (2012), Kristensen AR (2012)	3
AR	3	NONO	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ishitani K (2003), Ishitani K (2003), Ishitani K (2003), Dong X (2007)	4
MBD3	4	CHD4	22	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sakai H (2002), Cui S (2011), Havugimana PC (2012), Quan J (2014)	4
NONO	3	HDAC2	1	affinity chromatography technology	Zhang C (2008)	1
NR2C1	0	AR	3	affinity chromatography technology, two hybrid	Mu X (2003), Mu X (2003)	2
SFPQ	2	SIN3A	13	affinity chromatography technology, imaging technique, affinity chromatography technology	Tyson-Capper AJ (2009), Dong X (2007), Liu L (2011)	3
RBBP4	3	POLD3	0	affinity chromatography technology	Cui S (2011)	1
KDM1A	2	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013)	4
MBD3	4	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Sakai H (2002), Noh EJ (2009), Noh EJ (2009), Sun JM (2007), Adenuga D (2010), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	9
HCFC1	4	RBBP4	3	affinity chromatography technology	Wysocka J (2003)	1
ESR1	0	RBBP7	1	pull down, affinity chromatography technology	Creekmore AL (2008), Tarallo R (2011)	2
DNMT1	5	MBD3	4	affinity chromatography technology	Cui S (2011)	1
SMARCA4	19	CHD4	22	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shimono Y (2003), Shimono Y (2003), Shimono Y (2003), Mahajan MC (2005), Mahajan MC (2005), ONeill DW (2000)	6
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
NONO	3	SIN3A	13	affinity chromatography technology	Liu L (2011)	1
SIN3A	13	HDAC4	10	affinity chromatography technology, affinity chromatography technology	Farhana L (2007), Nakagawa Y (2006)	2
HDAC4	10	HDAC3	5	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Grozinger CM (1999), Fischle W (2002), Fischle W (2002), Fischle W (2002), Fischle W (2001), Grozinger CM (2000), Wang X (2008)	7
HDAC1	4	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Khan MM (2001), Khan MM (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Wu WS (2001), Morey L (2008), Kuo HY (2013), Kim YE (2015)	10
SFPQ	2	NONO	3	two hybrid, affinity chromatography technology, pull down, pull down, pull down, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Peng R (2002), Peng R (2002), Peng R (2002), Ito T (2008), Dong X (2007), Havugimana PC (2012), Wang J (2011), Hall-Pogar T (2007), Wan C (2015), Huttlin EL (2017)	10
NR2C1	0	MBD3	4	affinity chromatography technology	Cui S (2011)	1
RBM39	2	ESR1	0	pull down, two hybrid, pull down, affinity chromatography technology	Jung DJ (2002), Jung DJ (2002), Dowhan DH (2005), Tarallo R (2011)	4
ESR1	0	NR2C2	0	pull down, pull down	Shyr CR (2002), Shyr CR (2002)	2
AR	3	PSPC1	2	affinity chromatography technology	Ishitani K (2003)	1
NR2C1	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
TRIM28	1	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
SIN3A	13	MBD3	4	affinity chromatography technology	Nakamura T (2002)	1
MTA1	3	SIN3A	13	affinity chromatography technology	Yao YL (2003)	1
NR2C1	0	RBM39	2	affinity chromatography technology	Cui S (2011)	1
PML	7	HDAC3	5	affinity chromatography technology, pull down	Wu WS (2001), Wu WS (2001)	2
HDAC1	4	KDM1A	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2002), Hakimi MA (2003), You A (2001), You A (2001), Shi YJ (2005), Lee MG (2005), Humphrey GW (2001), Humphrey GW (2001), Humphrey GW (2001), Godmann M (2007), Godmann M (2007), Terhune SS (2010), Godmann M (2010), Godmann M (2010), Wang Y (2009), Nicholson TB (2011), Li Q (2011), Cui S (2011), Cui S (2011), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Wang Q (2016), Huttlin EL (2017)	26
CHD4	22	RBBP4	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Wan C (2015), Hauri S (2016)	9
KDM1A	2	MBD3	4	affinity chromatography technology, affinity chromatography technology, two hybrid	Wang Y (2009), Li Q (2011), Weimann M (2013)	3
CHD4	22	SIN3A	13	affinity chromatography technology	Zhang Y (1998)	1
KDM1A	2	SIN3A	13	affinity chromatography technology	You A (2001)	1
NR2C1	0	RCOR1	0	affinity chromatography technology	Cui S (2011)	1
NR2C1	0	SIN3A	13	affinity chromatography technology	Cui S (2011)	1
ESR1	0	SFPQ	2	pull down	Nalvarte I (2010)	1
MBD3	4	SMARCA4	19	pull down	Yildirim O (2011)	1
NR2C1	0	PML	7	affinity chromatography technology, imaging technique	Gupta P (2009), Chuang YS (2011)	2
TRIM28	1	HCFC1	4	biochemical	Wan C (2015)	1
NR2C1	0	SMARCA4	19	affinity chromatography technology	Cui S (2011)	1
ESR1	0	CHD4	22	affinity chromatography technology	Tarallo R (2011)	1
HCFC1	4	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Wysocka J (2003), Wysocka J (2003)	2
AR	3	SMARCA4	19	affinity chromatography technology, two hybrid, affinity chromatography technology, bioid	Wang Q (2004), van de Wijngaart DJ (2009), Dai Y (2008), Lempiaeinen JK (2017)	4
RBBP4	3	RBBP7	1	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
SMARCA4	19	RCOR1	0	affinity chromatography technology	Battaglioli E (2002)	1
HDAC3	5	RCOR1	0	affinity chromatography technology	Joshi P (2013)	1
HCFC1	4	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Wysocka J (2003), Wysocka J (2003)	2
TRIM28	1	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Cui S (2011)	2
MTA1	3	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Roche AE (2008), Huttlin EL (2015), Huttlin EL (2017), Millard CJ (2016), Hauri S (2016)	6
MBD3	4	RBBP7	1	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1999), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	5
DNMT1	5	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Cui S (2011), Cui S (2011), Cai Y (2014), Cai Y (2014), Wan C (2015)	5
MTA1	3	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Xue Y (1998), Cui S (2011), Cui S (2011), Chudnovsky Y (2014), Wan C (2015)	6
AR	3	HDAC3	5	pull down, affinity chromatography technology	Franco PJ (2003), Zhu P (2006)	2
HDAC2	1	PML	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu WS (2001), Morey L (2008), Kraemer OH (2008), Kim YE (2015)	4
DNMT1	5	MTA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cai Y (2014), Cai Y (2014), Cai Y (2014)	4
HDAC3	5	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Qiu Z (2008), Zhu P (2006)	2
RBBP4	3	HDAC3	5	pull down, pull down	Nicolas E (2001), Nicolas E (2001)	2
PSPC1	2	NONO	3	two hybrid, two hybrid, affinity chromatography technology	Stelzl U (2005), Rolland T (2014), Huttlin EL (2017)	3
KDM1A	2	NR2C2	0	affinity chromatography technology, two hybrid	Cui S (2011), Weimann M (2013)	2
DNMT1	5	HDAC3	5	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
RBBP4	3	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
HDAC2	1	KDM1A	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, genetic interference	Hakimi MA (2002), Hakimi MA (2003), Hakimi MA (2003), Hakimi MA (2003), Tong JK (1998), Lee MG (2005), Humphrey GW (2001), Humphrey GW (2001), Zibetti C (2010), Wang Y (2009), Li Q (2011), Cui S (2011), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Wong AS (2016)	17
NR2C1	0	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
MBD3	4	MTA1	3	pull down, affinity chromatography technology, biochemical	Yildirim O (2011), Cui S (2011), Wan C (2015)	3
NR2C1	0	NR2C2	0	affinity chromatography technology, biochemical, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
MTA2	1	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Cui S (2011), Wan C (2015)	4
NR2C1	0	HCFC1	4	affinity chromatography technology	Cui S (2011)	1
CHD4	22	RBBP7	1	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Havugimana PC (2012), Huttlin EL (2015), Quan J (2014), Huttlin EL (2017)	7
AR	3	RCOR1	0	bioid	Lempiaeinen JK (2017)	1
MTA2	1	KDM1A	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wang Y (2009), Wang Y (2009), Wang Y (2009), Li Q (2011), Cui S (2011)	5
ESR1	0	RBBP4	3	pull down, affinity chromatography technology	Creekmore AL (2008), Tarallo R (2011)	2
HDAC3	5	TRIM28	1	affinity chromatography technology	Tsuruma R (2008)	1
FOXL2	1	NR2C1	0	affinity chromatography technology	LHote D (2012)	1
SFPQ	2	HDAC2	1	affinity chromatography technology	Tyson-Capper AJ (2009)	1
NR2C1	0	MTA2	1	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
HCFC1	4	RBBP7	1	affinity chromatography technology	Wysocka J (2003)	1
KDM1A	2	TRIM28	1	affinity chromatography technology	Cui S (2011)	1
SMARCA4	19	RBBP4	3	biochemical	Sif S (2001)	1
HDAC2	1	DNMT1	5	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rountree MR (2000), Rountree MR (2000), Myant K (2008), Cui S (2011), Cai Y (2014), Cai Y (2014)	6
MTA1	3	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology	Yao YL (2003), Roche AE (2008), Cui S (2011), Cui S (2011), Rolland T (2014), Huttlin EL (2015), Alqarni SS (2014), Alqarni SS (2014), Alqarni SS (2014), Wan C (2015), Huttlin EL (2017), Millard CJ (2016), Millard CJ (2016), Millard CJ (2016), Hauri S (2016)	15
MTA1	3	ESR1	0	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Kumar R (2002), Kumar R (2002), Kumar R (2002), Mazumdar A (2001), Singh RR (2006), Mishra SK (2003)	6
PML	7	SIN3A	13	pull down, affinity chromatography technology	Khan MM (2001), Khan MM (2001)	2
NR2C1	0	PSPC1	2	affinity chromatography technology	Cui S (2011)	1
HDAC1	4	POLD3	0	affinity chromatography technology	Cui S (2011)	1
CHD4	22	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
NR2C1	0	SFPQ	2	affinity chromatography technology	Cui S (2011)	1
NR2C1	0	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
RBBP7	1	SIN3A	13	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Kuzmichev A (2002), Nakamura T (2002), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	6
DNMT1	5	RBBP4	3	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
HDAC1	4	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Yao YL (2003), Grozinger CM (1999), Tong JK (1998), Tong JK (1998), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Terhune SS (2010), Polo SE (2010), Xue Y (1998), Xue Y (1998), Xue Y (1998), Kwintkiewicz J (2011), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Quan J (2014), Wan C (2015), Hein MY (2015), Weiss K (2016), Huttlin EL (2017)	28
HDAC1	4	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
MBD3	4	HDAC1	4	affinity chromatography technology, biochemical, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sakai H (2002), Zhang Y (1999), Zhang Y (1999), Saito M (2002), Noh EJ (2009), Noh EJ (2009), Le Guezennec X (2006), Humphrey GW (2001), Sun JM (2007), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	16
NR2C2	0	HDAC3	5	pull down, affinity chromatography technology	Franco PJ (2003), Cui S (2011)	2
NR2C1	0	HDAC4	10	pull down, affinity chromatography technology, pull down	Franco PJ (2003), Franco PJ (2001), Franco PJ (2001)	3
RCOR1	0	KDM1A	2	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Hakimi MA (2002), You A (2001), You A (2001), Gocke CB (2008), Chen Y (2006), Yang M (2006), Shi YJ (2005), Shi YJ (2005), Lee MG (2005), Lee MG (2005), Humphrey GW (2001), Humphrey GW (2001), Zibetti C (2010), Hwang S (2011), Lin Y (2010), Nicholson TB (2011), Nicholson TB (2011), Cui S (2011), Adamo A (2011), Adamo A (2011), Bantscheff M (2011), Mosammaparast N (2013), Lin Y (2010), Wan C (2015), Boldt K (2016)	25
MTA2	1	RBBP7	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yao YL (2003), Zhang Y (1999), Feng Q (2001), Wang Y (2009), Fu J (2011), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Brasen C (2017), Brasen C (2017), Hauri S (2016)	11
RCOR1	0	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2002), You A (2001), You A (2001), Battaglioli E (2002), Humphrey GW (2001), Humphrey GW (2001), Bantscheff M (2011), Joshi P (2013)	8
HDAC2	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2003), Adenuga D (2010), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016)	9
MBD3	4	MTA2	1	affinity chromatography technology, biochemical, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sakai H (2002), Zhang Y (1999), Zhang Y (1999), Saito M (2002), Feng Q (2001), Wang Y (2009), Havugimana PC (2012), Wan C (2015)	8
NR2C1	0	HDAC3	5	pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Li G (2003), Li G (2003), Franco PJ (2003), Franco PJ (2003), Franco PJ (2001), Franco PJ (2001), Franco PJ (2001), Gupta P (2009), Gupta P (2009), Gupta P (2009), Cui S (2011), Cui S (2011)	12
CHD4	22	KDM1A	2	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
HDAC1	4	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Qiu Z (2008), Battaglioli E (2002), Hang CT (2010), DiRenzo J (2000)	4
SIN3A	13	RBBP4	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hassig CA (1997), Zhang Y (1998), Nakamura T (2002), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Bantscheff M (2011), Hauri S (2016)	8
TRIM28	1	MTA2	1	biochemical	Kristensen AR (2012)	1
SFPQ	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tyson-Capper AJ (2009), Dong L (2011), Liu L (2011), Zhong N (2006), Zhong N (2006)	5
AR	3	KDM1A	2	affinity chromatography technology, bioid	Choi H (2016), Lempiaeinen JK (2017)	2
DNMT1	5	POLD3	0	affinity chromatography technology	Cui S (2011)	1
PML	7	CHD4	22	affinity chromatography technology	Morey L (2008)	1
MTA2	1	ESR1	0	pull down, pull down, affinity chromatography technology	Cui Y (2006), Cui Y (2006), Cui Y (2006)	3
SMARCA4	19	PML	7	imaging technique	Chuang YS (2011)	1
ESR1	0	PSPC1	2	pull down	Nalvarte I (2010)	1
HDAC2	1	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Hakimi MA (2003), Schmidt DR (1999), Schmidt DR (1999), Tong JK (1998), Tong JK (1998), Tong JK (1998), ONeill DW (2000), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	17
SMARCA4	19	NONO	3	affinity chromatography technology, pull down, affinity chromatography technology	Ito T (2008), Ito T (2008), Tando T (2010)	3
DNMT1	5	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson KD (2000), Achour M (2008), Achour M (2008), Kimura H (2003), Zhang Q (2005), Myant K (2008), Schnekenburger M (2007), Kang KA (2012), Cui S (2011), Cui S (2011), Hervouet E (2010), Cai Y (2014), Cai Y (2014), Yuan K (2016), Yuan K (2016)	15
KDM1A	2	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li Q (2011), Cui S (2011), Cui S (2011)	3
HDAC3	5	ESR1	0	imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Liu XF (2004), Zhu P (2006), Nalvarte I (2010), Han SJ (2016)	4
MTA2	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Zhang Y (1999), Banach-Orlowska M (2009), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Wang Y (2009), Fu J (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	14
NUDT3	0	NR2C1	0	two hybrid	Vinayagam A (2011)	1
HCFC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Yokoyama A (2004), Wysocka J (2003), Wysocka J (2003), Wysocka J (2003), Mangone M (2010)	5
MTA2	1	RBBP4	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology	Yao YL (2003), Zhang Y (1999), Banach-Orlowska M (2009), Pflum MK (2001), Feng Q (2001), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Wan C (2015), Brasen C (2017), Brasen C (2017), Brasen C (2017), Hauri S (2016)	13
SMARCA4	19	SIN3A	13	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sif S (2001), Sif S (2001), Kuzmichev A (2002), Kuzmichev A (2002), Qiu Z (2008), Xu Z (2006), Pal S (2003), Pal S (2003)	8
HDAC1	4	RBBP7	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Ng HH (1999), Zhang Y (1999), Zhang Y (1997), Banach-Orlowska M (2009), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Yeh HH (2015), Yeh HH (2015), Huttlin EL (2017), Hauri S (2016)	19
RBBP4	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Nicolas E (2001), Nicolas E (2001), Grozinger CM (1999), You A (2001), Hassig CA (1997), Hassig CA (1997), Ng HH (1999), Zhang Y (1999), Zhang Y (2002), Hassig CA (1998), Zhang Y (1997), Banach-Orlowska M (2009), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	35
HDAC1	4	MTA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Yao YL (2003), You A (2001), Zhang Y (1999), Zhang Y (1999), Yasui D (2002), Banach-Orlowska M (2009), Banach-Orlowska M (2009), Cui Y (2006), Pflum MK (2001), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Humphrey GW (2001), Zhang Y (1998), Terhune SS (2010), Opsahl JA (2010), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	27
CHD4	22	POLD3	0	affinity chromatography technology	Cui S (2011)	1
ESR1	0	KDM1A	2	affinity chromatography technology, affinity chromatography technology	Garcia-Bassets I (2007), Garcia-Bassets I (2007)	2
HDAC1	4	NONO	3	imaging technique, affinity chromatography technology, affinity chromatography technology	Dong X (2007), Liu L (2011), Zhang C (2008)	3
ESR1	0	HDAC4	10	pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	van Rooij E (2010), Leong H (2005), Leong H (2005), Leong H (2005), Leong H (2005)	5
NR2C1	0	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
NR2C2	0	HDAC4	10	pull down	Franco PJ (2003)	1
NR2C1	0	ESR1	0	affinity chromatography technology, pull down	Hu YC (2002), Hu YC (2002)	2
SIN3A	13	ESR1	0	affinity chromatography technology, affinity chromatography technology	Ellison-Zelski SJ (2009), Zhu P (2006)	2
MTA1	3	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
AR	3	SIN3A	13	affinity chromatography technology	Zhu P (2006)	1
MTA2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Pflum MK (2001)	2
HDAC4	10	RBBP4	3	affinity chromatography technology	Grozinger CM (1999)	1
DNMT1	5	NR2C2	0	affinity chromatography technology	Cui S (2011)	1
MBD3	4	RBBP4	3	pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (1999), Cui S (2011), Havugimana PC (2012), Hauri S (2016)	4
NR2C1	0	KDM1A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011), Cui S (2011)	3
DNMT1	5	RBBP7	1	affinity chromatography technology, affinity chromatography technology	Marin TL (2017), Marin TL (2017)	2
ESR1	0	NONO	3	pull down	Nalvarte I (2010)	1
TRIM28	1	SMARCA4	19	affinity chromatography technology	Seki Y (2010)	1
HDAC2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014)	20
NONO	3	HDAC3	5	affinity chromatography technology	Zhang C (2008)	1
AR	3	SFPQ	2	affinity chromatography technology, pull down	Dong X (2007), Dong X (2007)	2
SMARCA4	19	ESR1	0	two hybrid, pull down	Ichinose H (1997), DiRenzo J (2000)	2