PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
FYN	1	SYK	3	affinity chromatography technology, pull down	Deckert M (1998), Deckert M (1998)	2
ERBB2	6	JAK2	1	affinity chromatography technology	Ren Z (2002)	1
VAV1	2	JUN	0	enzymatic study	Kaminuma O (2001)	1
TUBA1A	13	TUBB	3	biochemical, biochemical, pull down	Havugimana PC (2012), Kristensen AR (2012), Wang W (2014)	3
VAV1	2	EZH2	4	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Hobert O (1996), Hobert O (1996), Hobert O (1996), Su IH (2005)	4
JAK2	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Olayioye MA (1999), Olayioye MA (1999), Jones RB (2006), He K (2013)	4
NOTCH1	25	CBL	7	affinity chromatography technology, affinity chromatography technology	Jehn BM (2002), Platonova N (2015)	2
SLA	2	ZAP70	5	affinity chromatography technology	Tang J (1999)	1
CD5	1	PTPN6	0	affinity chromatography technology	Perez-Villar JJ (1999)	1
IL6ST	0	PTPN6	0	affinity chromatography technology	Bartoe JL (2000)	1
VAV1	2	SPECC1L	5	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	APBB2	2	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
SLA	2	VAV1	2	affinity chromatography technology, pull down	Sosinowski T (2000), Sosinowski T (2000)	2
CBLB	3	VAV1	2	affinity chromatography technology, two hybrid, pull down, far western blotting, affinity chromatography technology	Sattler M (2002), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997)	5
TYK2	1	SIAH2	0	affinity chromatography technology	Mueller S (2014)	1
EGFR	5	SLA	2	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
CD19	3	VAV1	2	affinity chromatography technology, affinity chromatography technology	Weng WK (1994), Lottin-Divoux S (2006)	2
SH3BP2	4	CBL	7	pull down, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
CBL	7	TUBB	3	affinity chromatography technology, affinity chromatography technology	Teckchandani AM (2005), Brehme M (2009)	2
SHB	4	ABL1	9	affinity chromatography technology, affinity chromatography technology, pull down	Haegerkvist R (2007), Haegerkvist R (2007), Haegerkvist R (2007)	3
GRB2	2	KHDRBS1	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, two hybrid	Liu SK (1998), Oneyama C (2002), Shen Z (1999), Shen Z (1999), Bandyopadhyay S (2010), Asbach B (2012), Bisson N (2011), Wang J (2011)	8
ERBB2	6	DOK1	2	unspecified method	Jones RB (2006)	1
SHB	4	LAT	0	affinity chromatography technology, affinity chromatography technology	Lindholm CK (1999), Lindholm CK (2002)	2
PLCG2	11	SYK	3	affinity chromatography technology	Guo B (2000)	1
EED	1	XRCC6	3	affinity chromatography technology	Cao Q (2014)	1
PTPN22	3	GRB2	2	affinity chromatography technology	Hill RJ (2002)	1
VAV1	2	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
SH3BP2	4	PLCG1	6	pull down, far western blotting	Deckert M (1998), Jevremovic D (2001)	2
PTK2B	6	FYN	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ganju RK (1997), Katagiri T (2000), Qian D (1997), Qian D (1997), Marie-Cardine A (1999)	5
IL6ST	0	TYK2	1	affinity chromatography technology	Kim H (1997)	1
LCP2	0	PAG1	5	pull down	Brdicka T (2000)	1
VAV1	2	PAG1	5	pull down	Brdicka T (2000)	1
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
NOTCH1	25	VAV1	2	affinity chromatography technology	Yatim A (2012)	1
CHEK1	2	XRCC5	5	affinity chromatography technology	Goudelock DM (2003)	1
VAV1	2	LCP2	0	affinity chromatography technology, pull down, affinity chromatography technology	Raab M (1997), Onodera H (1996), Shen M (2009)	3
ABL1	9	PLCG1	6	pull down	Koch A (2000)	1
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
CBL	7	ABL1	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, far western blotting, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Soubeyran P (2003), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Patel H (2006), Johnson KJ (2009), Shishido T (2000), Shishido T (2000), Shishido T (2000), Gaston I (2004), Jain SK (1997), Reedquist KA (1996), Bhat A (1997), Bhat A (1997), Bhat A (1997), Grossmann AH (2004), Brehme M (2009), Brehme M (2009), Brehme M (2009), Nishihara T (2003), Tsukahara F (2010)	21
VAV1	2	ABL1	9	pull down, two hybrid, affinity chromatography technology, enzymatic study	Bassermann F (2002), Bassermann F (2002), Bassermann F (2002), Bassermann F (2002)	4
PTPN6	0	LAT	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016), Matalon O (2016)	3
HNRNPK	4	XRCC6	3	biochemical	Wan C (2015)	1
ZAP70	5	CD5	1	affinity chromatography technology	Gary-Gouy H (1997)	1
FYN	1	KHDRBS1	1	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study	Oneyama C (2002), Fusaki N (1997), Loewenberg M (2006), Asbach B (2012), Asbach B (2012), Kaabeche K (2004)	6
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
VAV1	2	RAF1	3	affinity chromatography technology	Song JS (1996)	1
VAV1	2	APBB2	2	affinity chromatography technology	Huttlin EL (2017)	1
DOK1	2	PLCG1	6	pull down	van Dijk TB (2000)	1
S100B	0	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down	Fackler OT (1999), Fackler OT (1999), Fackler OT (1999)	3
CBLB	3	PLCG2	11	affinity chromatography technology	Yasuda T (2002)	1
VAV1	2	RACGAP1	2	pull down	Das B (2000)	1
VAV1	2	PDGFRB	8	affinity chromatography technology, unspecified method	Moores SL (2000), Liu BA (2012)	2
SLA	2	SYK	3	affinity chromatography technology	Tang J (1999)	1
ERBB3	3	ACTBL2	0	affinity chromatography technology	Li J (2013)	1
VAV1	2	CD5	1	biochemical	Roa NS (2013)	1
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
VAV1	2	ARHGDIB	1	two hybrid, affinity chromatography technology, pull down	Groysman M (2000), Groysman M (2000), Groysman M (2000)	3
EGFR	5	HNRNPK	4	affinity chromatography technology	Yao Z (2017)	1
ERBB3	3	TUBB	3	affinity chromatography technology	Li J (2013)	1
BTK	1	CBL	7	pull down, x-ray crystallography, unspecified method, affinity chromatography technology	Cory GO (1995), Tzeng SR (2000), Patel HV (1997), Morrogh LM (1999)	4
JAK2	1	EPOR	3	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang LJ (2001), Huang LJ (2001), Witthuhn BA (1993), van den Akker E (2004)	4
EGFR	5	EMD	0	biochemical, affinity chromatography technology, affinity chromatography technology	Wang YN (2010), Tong J (2014), Yao Z (2017)	3
PLCG1	6	LAT	0	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Zhang W (1998), Paz PE (2001), Paz PE (2001), Zhang W (1998), Jiang Y (2007), Braiman A (2006), Braiman A (2006), Matalon O (2016), Matalon O (2016)	9
HNRNPK	4	VAV1	2	affinity chromatography technology	Hobert O (1994)	1
GRB2	2	BTK	1	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
ERBB2	6	SYK	3	unspecified method	Jones RB (2006)	1
INSR	9	KHDRBS1	1	affinity chromatography technology	Sanchez-Margalet V (2001)	1
DOCK2	3	HNRNPK	4	two hybrid	Rolland T (2014)	1
JUN	0	MAPK1	1	affinity chromatography technology, enzymatic study, pull down	Kumar NV (2001), Zuniga A (1999), Zuniga A (1999)	3
MAPK1	1	RAF1	3	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Lin YL (2000), Dougherty MK (2005), Zhu J (2005), Blaukat A (2000), Wang J (2009), Wang J (2009), Wang J (2009)	7
EED	1	HNRNPK	4	affinity chromatography technology	Cao Q (2014)	1
ZAP70	5	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
GRB2	2	TEC	2	affinity chromatography technology	Bisson N (2011)	1
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
EPOR	3	GRB2	2	pull down, pull down, affinity chromatography technology	Tauchi T (1995), Feng GS (1996), Barber DL (1997)	3
DOCK2	3	VAV1	2	affinity chromatography technology	Nishihara H (2002)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
VAV1	2	INSR	9	pull down	Uddin S (1995)	1
SHB	4	ZAP70	5	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
ERBB3	3	PTK2B	6	affinity chromatography technology	Verma N (2017)	1
EGFR	5	DOK1	2	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
EPOR	3	SYK	3	affinity chromatography technology	Duprez V (1998)	1
FYN	1	TYK2	1	affinity chromatography technology, pull down	Uddin S (1997), Uddin S (1997)	2
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
VAV1	2	PLBD1	0	affinity chromatography technology	Huttlin EL (2017)	1
PLCG2	11	VAV1	2	affinity chromatography technology	Guo B (2000)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
BLNK	2	SYK	3	affinity chromatography technology, affinity chromatography technology	Oellerich T (2011), Janda E (2011)	2
GRB2	2	RACGAP1	2	affinity chromatography technology	Blagoev B (2003)	1
PLCG2	11	PLCG1	6	imaging technique	Chen TC (2014)	1
BTK	1	KHDRBS1	1	affinity chromatography technology, unspecified method	Guinamard R (1997), Asbach B (2012)	2
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
PTK2B	6	GRB2	2	affinity chromatography technology, affinity chromatography technology	Blaukat A (1999), Bruzzaniti A (2009)	2
VAV1	2	NUB1	2	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
RAF1	3	JAK2	1	pull down	Xia K (1996)	1
PIK3R1	6	JAK2	1	pull down, genetic interference	Ren SY (2005), Shen JP (2017)	2
LAT	0	PIK3R1	6	affinity chromatography technology, pull down	Paz PE (2001), Paz PE (2001)	2
SYK	3	TUBA1A	13	enzymatic study	Faruki S (2000)	1
VAV1	2	PTPN6	0	pull down	Kon-Kozlowski M (1996)	1
VAV1	2	SIAH2	0	two hybrid, pull down, affinity chromatography technology	Germani A (1999), Germani A (1999), Germani A (1999)	3
PLCG1	6	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
SUZ12	0	KHDRBS1	1	affinity chromatography technology	Cao Q (2014)	1
PLCG1	6	ERBB2	6	affinity chromatography technology, biochemical, unspecified method	Peles E (1991), Arteaga CL (1991), Jones RB (2006)	3
KLK7	0	CDSN	1	enzymatic study	Caubet C (2004)	1
VAV1	2	DSG1	1	affinity chromatography technology	Huttlin EL (2017)	1
KHDRBS1	1	HNRNPK	4	two hybrid, pull down, affinity chromatography technology, pull down, genetic interference, genetic interference, two hybrid, two hybrid, two hybrid	Yang JP (2002), Yang JP (2002), Yang JP (2002), Yang JP (2002), Yang JP (2002), Yang JP (2002), Hegele A (2012), Hegele A (2012), Wang J (2011)	9
LAT	0	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Paz PE (2001), Zhang W (1998), Perez-Villar JJ (2002), Motto DG (1994), Houtman JC (2006)	5
ABL1	9	PTPN6	0	affinity chromatography technology	Kharbanda S (1996)	1
VAV1	2	EED	1	affinity chromatography technology	Su IH (2005)	1
RACGAP1	2	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
VAV1	2	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Song JS (1996), Lee IS (1997)	2
GRB2	2	SOCS1	1	pull down	De Sepulveda P (1999)	1
JAK2	1	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chauhan D (1995), Chauhan D (1995), Giorgetti-Peraldi S (1995), Brizzi MF (1996)	4
SHB	4	PLCG1	6	affinity chromatography technology	Lindholm CK (1999)	1
ERBB2	6	TEC	2	unspecified method	Jones RB (2006)	1
SYK	3	PIK3R1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Moon KD (2005), Moon KD (2005), Moon KD (2005), Moon KD (2005), Huang ZY (2006)	5
INSR	9	JAK2	1	affinity chromatography technology, affinity chromatography technology	Maegawa H (1996), Le MN (2002)	2
EGFR	5	RAF1	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
IL6ST	0	JAK2	1	affinity chromatography technology	Kim H (1997)	1
CBLB	3	PTK2B	6	affinity chromatography technology	Fan Y (2014)	1
EMD	0	TUBB	3	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	TUBB	3	affinity chromatography technology	Foerster S (2013)	1
VAV1	2	PHAX	0	two hybrid	Vinayagam A (2011)	1
ABL1	9	PAG1	5	two hybrid, affinity chromatography technology	Wen ST (1997), Wen ST (1997)	2
EMD	0	VAV1	2	two hybrid	Wilkinson FL (2003)	1
CBLB	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Zhang Z (1999), Kumar S (2011)	2
SH3BP2	4	ZAP70	5	affinity chromatography technology, pull down	Deckert M (1998), Deckert M (1998)	2
RAF1	3	EMD	0	affinity chromatography technology	So J (2015)	1
CBL	7	ZAP70	5	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography	Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017)	11
VAV1	2	EGFR	5	affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Moores SL (2000), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	4
RAF1	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC42	3	VAV1	2	affinity chromatography technology	Kaminuma O (2001)	1
VAV1	2	ZAP70	5	pull down, affinity chromatography technology	Katzav S (1994), Huby RD (1995)	2
VAV1	2	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bertagnolo V (1998), Bertagnolo V (1998), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
SH3BP2	4	LAT	0	pull down, affinity chromatography technology	Deckert M (1998), Jevremovic D (2001)	2
VAV1	2	MS4A2	1	affinity chromatography technology	Song JS (1996)	1
SHB	4	PIK3R1	6	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
FGFR1	2	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
FYN	1	SH3BP2	4	two hybrid	Deckert M (1998)	1
SIAH1	2	VAV1	2	two hybrid	Germani A (1999)	1
EMD	0	HNRNPK	4	affinity chromatography technology	Holaska JM (2007)	1
EGFR	5	PTK2B	6	affinity chromatography technology, affinity chromatography technology	Keely SJ (2000), Ivankovic-Dikic I (2000)	2
SOCS1	1	ERBB2	6	unspecified method	Jones RB (2006)	1
PTPN22	3	CBL	7	affinity chromatography technology	Cohen S (1999)	1
BLNK	2	VAV1	2	affinity chromatography technology	Fu C (1998)	1
ERBB2	6	SH3BP2	4	unspecified method	Jones RB (2006)	1
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
ZAP70	5	ABL1	9	affinity chromatography technology	Neumeister EN (1995)	1
ERBB3	3	SYK	3	unspecified method	Jones RB (2006)	1
TUBB	3	SYK	3	affinity chromatography technology	Fernandez JA (1999)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
EGFR	5	XRCC5	5	affinity chromatography technology	Tong J (2014)	1
RAC1	7	DOCK2	3	pull down	Nishihara H (1999)	1
JAK2	1	PTK2B	6	affinity chromatography technology	Frank GD (2002)	1
IL6ST	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Grant SL (2002), Grant SL (2002)	2
LAT	0	CBL	7	affinity chromatography technology	Jiang Y (2007)	1
HNRNPK	4	TYK2	1	two hybrid	Rolland T (2014)	1
EGFR	5	ACTA2	1	affinity chromatography technology	Tong J (2009)	1
VAV1	2	CST6	1	affinity chromatography technology	Huttlin EL (2017)	1
TEC	2	SOCS1	1	pull down, two hybrid	Ohya K (1997), Ohya K (1997)	2
KHDRBS1	1	DOCK2	3	unspecified method	Asbach B (2012)	1
JAK2	1	TEC	2	affinity chromatography technology, enzymatic study	Takahashi-Tezuka M (1997), Yamashita Y (1998)	2
JAK2	1	EMD	0	affinity chromatography technology	So J (2015)	1
KHDRBS1	1	VAV1	2	unspecified method	Asbach B (2012)	1
ZAP70	5	LCP2	0	enzymatic study, enzymatic study	Raab M (1997), Kim KS (2002)	2
BTK	1	SYK	3	affinity chromatography technology	Morrogh LM (1999)	1
SYK	3	PTK2B	6	affinity chromatography technology	Ganju RK (2000)	1
JAK2	1	VAV1	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Matsuguchi T (1995)	3
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
BLNK	2	CBL	7	affinity chromatography technology, far western blotting	Yasuda T (2000), Yasuda T (2000)	2
INSR	9	GRB2	2	affinity chromatography technology	Ishihara H (1997)	1
FYN	1	PLCG2	11	pull down	Pleiman CM (1993)	1
MAPK1	1	CHEK1	2	biochemical	Wan C (2015)	1
SPI1	1	JUN	0	pull down	Carrere S (1998)	1
FGFR1	2	SH3BP2	4	two hybrid	Hu Y (2004)	1
VAV1	2	CDSN	1	affinity chromatography technology	Huttlin EL (2017)	1
ERBB2	6	VAV1	2	unspecified method	Jones RB (2006)	1
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
SLA	2	LAT	0	affinity chromatography technology	Tang J (1999)	1
EGFR	5	PDGFRB	8	affinity chromatography technology	Habib AA (1998)	1
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
JAK2	1	ERBB3	3	unspecified method	Jones RB (2006)	1
LAT	0	VAV1	2	pull down, pull down, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Perez-Villar JJ (2002)	3
PTPN6	0	PTK2B	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Ganju RK (2000), Kumar S (1999), Kumar S (1999), Kumar S (1999)	5
BTK	1	PLCG2	11	affinity chromatography technology, affinity chromatography technology	Yasuda T (2002), Guo B (2000)	2
VAV1	2	APLP2	2	affinity chromatography technology	Huttlin EL (2017)	1
XRCC5	5	TYK2	1	affinity chromatography technology, affinity chromatography technology	Adam L (2000), Adam L (2000)	2
IL6ST	0	GRB2	2	pull down, affinity chromatography technology	Lee IS (1997), Lee IS (1997)	2
CDC42	3	CBL	7	affinity chromatography technology, pull down, affinity chromatography technology	Wu WJ (2003), Wu WJ (2003), Simmons A (2005)	3
VAV1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
ABL1	9	EGFR	5	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
BTK	1	BLNK	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yasuda T (2002), Hashimoto S (1999), Hashimoto S (1999), Oellerich T (2011), Janda E (2011)	5
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
VAV1	2	SPI1	1	affinity chromatography technology, affinity chromatography technology	Brugnoli F (2010), Brugnoli F (2010)	2
SYK	3	MS4A2	1	pull down	Kihara H (1994)	1
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
GRB2	2	CD28	0	pull down, pull down	Okkenhaug K (1998), Nunes JA (1996)	2
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
PTPN6	0	INSR	9	affinity chromatography technology	Uchida T (1994)	1
NOTCH1	25	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
CHEK1	2	MAP2K1	8	genetic interference	Shen JP (2017)	1
PDGFRB	8	PLCG1	6	affinity chromatography technology, unspecified method	Kashishian A (1993), Liu BA (2012)	2
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
PTPN6	0	PAG1	5	pull down	Brdicka T (2000)	1
RAC1	7	VAV1	2	affinity chromatography technology	Kaminuma O (2001)	1
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
ZAP70	5	PTPN6	0	pull down	Plas DR (1996)	1
TUBA1A	13	CBL	7	affinity chromatography technology	Teckchandani AM (2005)	1
CBL	7	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Bertagnolo V (2001), Miura-Shimura Y (2003), Simmons A (2005), Shen M (2009), Shen M (2009), Lottin-Divoux S (2006), Lottin-Divoux S (2006), Peterson ME (2008)	12
MAPK1	1	INSR	9	affinity chromatography technology	Lin YL (2000)	1
VAV1	2	KLK7	0	affinity chromatography technology	Huttlin EL (2017)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
TYK2	1	SOCS1	1	affinity chromatography technology	Piganis RA (2011)	1
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
EED	1	XRCC5	5	affinity chromatography technology	Cao Q (2014)	1
FYN	1	RAF1	3	affinity chromatography technology, pull down	Cleghon V (1994), Cleghon V (1994)	2
VAV1	2	ACTBL2	0	affinity chromatography technology	Huttlin EL (2017)	1
XRCC5	5	CBL	7	affinity chromatography technology	Hein MY (2015)	1
SOCS1	1	ABL1	9	affinity chromatography technology	Qiu X (2012)	1
SUZ12	0	EMD	0	affinity chromatography technology	Cao Q (2014)	1
PLCG1	6	KHDRBS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Oneyama C (2002), Jabado N (1998), Shen Z (1999), Shen Z (1999), Jabado N (1997), Jabado N (1997)	6
VAV1	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song JS (1996), Ye ZS (1994), Ye ZS (1994), Germani A (1999), Lee IS (1997)	5
FGFR1	2	PLCG1	6	two hybrid, imaging technique, two hybrid, pull down, enzymatic study, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology	Xu H (1998), Chen TC (2014), Hu Y (2004), Shi E (1993), Shi E (1993), Bae JH (2009), Bae JH (2009), Bae JH (2009), Browaeys-Poly E (2010), Browaeys-Poly E (2010), Vecchione A (2007)	11
JAK2	1	PLCG1	6	affinity chromatography technology	Chang YJ (2004)	1
MAPK1	1	MAP2K1	8	affinity chromatography technology, enzymatic study, two hybrid, pull down, pull down, pull down, enzymatic study, affinity chromatography technology, enzymatic study, protein complementation assay, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sanz-Moreno V (2003), Sanz-Moreno V (2003), Robinson FL (2002), Yeung K (2000), Yeung K (2000), Wunderlich W (2001), Xu Be (2001), Xu Be (2001), Chen Z (2001), Srivastav RK (2011), Kubota Y (2011), Ho DT (2003), Wang J (2009), Jahrling JB (2014)	14
CBL	7	SYK	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Lupher ML (1998), Lupher ML (1998), Bertagnolo V (2001), Melander F (2003), Macglashan D (2004), Rao N (2001), Rao N (2001), Yankee TM (1999), Saci A (2000), Moon KD (2005), Lottin-Divoux S (2006), Grossmann AH (2004), Ota S (2000), Ota S (2000), Panchamoorthy G (1996), Marcilla A (1995), Justa-Schuch D (2016)	17
SOCS1	1	VAV1	2	affinity chromatography technology, affinity chromatography technology	De Sepulveda P (1999), De Sepulveda P (2000)	2
EGFR	5	ZAP70	5	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
EED	1	SUZ12	0	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pasini D (2004), Cao R (2004), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Sarma K (2008), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Hein MY (2015), Chan YS (2013), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Wang X (2017), Hauri S (2016), Hauri S (2016)	22
SHB	4	VAV1	2	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
FGFR1	2	JAK2	1	affinity chromatography technology	Dudka AA (2010)	1
IL6ST	0	VAV1	2	pull down	Lee IS (1997)	1
PIK3R1	6	EPOR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Damen JE (1995), Damen JE (1995), Montoye T (2005), Bulut GB (2013)	6
GRB2	2	HNRNPK	4	two hybrid, affinity chromatography technology, two hybrid, two hybrid	Bandyopadhyay S (2010), Brehme M (2009), Wang J (2011), Rolland T (2014)	4
EZH2	4	SUZ12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su IH (2005), Aoto T (2008), Hansen KH (2008), Li G (2010), Margueron R (2008), Margueron R (2008), Shen X (2008), Pasini D (2008), Pasini D (2008), Sarma K (2008), Xu B (2011), Xu B (2011), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Lee ST (2011), Havugimana PC (2012), Sahasrabuddhe AA (2014), Wang L (2013), Wu L (2013), Pasini D (2010), Pasini D (2010), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Bhatnagar S (2014), Bhatnagar S (2014), Zhao R (2015), Wienken M (2016), Huttlin EL (2017), Zhang H (2016), Zhang H (2016), Mahara S (2016), Hauri S (2016), Hauri S (2016)	40
TYK2	1	CBL	7	affinity chromatography technology	Uddin S (1996)	1
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
PTPN6	0	SYK	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Dustin LB (1999), Dustin LB (1999)	3
VAV1	2	XRCC6	3	two hybrid, pull down, affinity chromatography technology	Romero F (1996), Romero F (1996), Romero F (1996)	3
GRB2	2	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid	Lewitzky M (2001), Robinson A (1996), Erdreich-Epstein A (1999), Hendricks-Taylor LR (1997), Asada H (1999), Bandyopadhyay S (2010), Chu J (1998), Berry DM (2002), Brehme M (2009), Rolland T (2014)	10
ERBB3	3	ACTA2	1	affinity chromatography technology	Li J (2013)	1
VAV1	2	SUZ12	0	affinity chromatography technology	Su IH (2005)	1
RAF1	3	PDGFRB	8	pull down	Morrison DK (1989)	1
ZAP70	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, pull down	Nel AE (1995), Braiman A (2006), Hubert P (1996)	3
JAK2	1	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Jiao H (1996), Wu DW (2000)	2
PTPN6	0	BLNK	2	affinity chromatography technology	Adachi T (2001)	1
ZAP70	5	LAT	0	enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Houtman JC (2006), Xie JJ (2013)	4
PTK2B	6	ERBB2	6	affinity chromatography technology, imaging technique	Zrihan-Licht S (2000), Chen TC (2014)	2
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
IL6ST	0	PIK3R1	6	affinity chromatography technology	Chung TD (2000)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
JAK2	1	SOCS1	1	two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yasukawa H (1999), Dif F (2001), Endo TA (1997), Endo TA (1997), Endo TA (1997), Yasukawa H (1999), Yasukawa H (1999), Pezet A (1999), Ungureanu D (2002), Masuhara M (1997), Ali S (2003), Monni R (2001), Monni R (2001), Piessevaux J (2008), Yu L (2009), Maruoka M (2017)	16
ZAP70	5	TUBB	3	affinity chromatography technology	Huby RD (1995)	1
TEC	2	VAV1	2	affinity chromatography technology	Kline JB (2001)	1
PTPN22	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
INSR	9	SOCS1	1	affinity chromatography technology	Mooney RA (2001)	1
TUBA1A	13	CHEK1	2	genetic interference	Srivas R (2016)	1
PTPN22	3	VAV1	2	affinity chromatography technology	Wu J (2006)	1
PLCG1	6	BLNK	2	affinity chromatography technology	Yasuda T (2000)	1
EPOR	3	CBL	7	affinity chromatography technology	Wakioka T (1999)	1
DOK1	2	VAV1	2	unspecified method	Liu BA (2012)	1
FYN	1	PAG1	5	pull down, affinity chromatography technology	Brdicka T (2000), Brdicka T (2000)	2
ABL1	9	ERBB2	6	unspecified method	Jones RB (2006)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
APBB2	2	APLP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VAV1	2	PRKCQ	3	genetic interference, affinity chromatography technology, affinity chromatography technology	Hehner SP (2000), Hehner SP (2000), Hehner SP (2000)	3
ERBB3	3	ZAP70	5	unspecified method	Jones RB (2006)	1
ABL1	9	GRB2	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Warmuth M (1997), Ren R (1994), Ren R (1994), Patel H (2006), Johnson KJ (2009), Gaston I (2004), Gaston I (2004), Brehme M (2009), Brehme M (2009), Chen R (2013), Feller SM (1994)	11
EGFR	5	TUBA1A	13	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
FGFR1	2	VAV1	2	unspecified method	Liu BA (2012)	1
VAV1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bertagnolo V (1998), Bertagnolo V (1998), Bertagnolo V (1998), Shigematsu H (1997), Shigematsu H (1997), Shigematsu H (1997)	6
CBLB	3	MS4A2	1	biochemical	Qu X (2005)	1
DOK1	2	PIK3R1	6	pull down, unspecified method	van Dijk TB (2000), Liu BA (2012)	2
INSR	9	DOK1	2	enzymatic study	Wick MJ (2001)	1
CD19	3	SYK	3	affinity chromatography technology	Carter RH (1997)	1
VAV1	2	EPOR	3	affinity chromatography technology	Shigematsu H (1997)	1
FYN	1	VAV1	2	affinity chromatography technology, two hybrid	Michel F (1998), Tartare-Deckert S (2001)	2
CBL	7	SLA	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang J (1999), Myers MD (2006), Sirvent A (2008), Swaminathan G (2007)	4
EGFR	5	LAT	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
VAV1	2	SDR9C7	0	affinity chromatography technology	Huttlin EL (2017)	1
PDGFRB	8	CBLB	3	affinity chromatography technology	Rorsman C (2016)	1
EZH2	4	EED	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Lohuizen M (1998), van Lohuizen M (1998), van Lohuizen M (1998), van der Vlag J (1999), van der Vlag J (1999), van der Vlag J (1999), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Denisenko O (1998), Pasini D (2004), Cao R (2004), Su IH (2005), Hansen KH (2008), Margueron R (2008), Margueron R (2008), Shen X (2008), Shen X (2008), Hernandez-Munoz I (2005), Sarma K (2008), Sarma K (2008), Han Z (2007), Avdic V (2011), Kaneko S (2010), Kaneko S (2010), Yap DB (2011), Satijn DP (2001), Satijn DP (2001), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Sewalt RG (1998), Wang L (2013), Wu L (2013), Pasini D (2010), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014), Wan C (2015), Hein MY (2015), Hein MY (2015), Chan YS (2013), Zhang H (2016), Zhang H (2016), Wang X (2017), Hauri S (2016), Hauri S (2016)	49
DOK1	2	ABL1	9	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	van Dijk TB (2000), Yamanashi Y (1997), Yamanashi Y (1997), Johnson KJ (2009), Liu BA (2012), Bhat A (1998), Bhat A (1998), Bhat A (1998), Kashige N (2000)	9
CD5	1	CBL	7	affinity chromatography technology, biochemical	Dennehy KM (1998), Roa NS (2013)	2
GRB2	2	CDC42	3	two hybrid	Vinayagam A (2011)	1
FYN	1	LAT	0	enzymatic study	Jiang Y (2007)	1
EGFR	5	PTPN22	3	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
SHB	4	GRB2	2	affinity chromatography technology	Welsh M (1998)	1
ABL1	9	PIK3R1	6	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Kapeller R (1994), Ren SY (2005), Ren SY (2005), Ren SY (2005), Brehme M (2009)	5
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
PIK3R1	6	KHDRBS1	1	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Shen Z (1999), Shen Z (1999), Asbach B (2012), Asbach B (2012), Asbach B (2012), Sung CK (1994), Sung CK (1994)	8
LCP2	0	PLCG1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Yablonski D (2001), Yablonski D (2001), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
SYK	3	VAV1	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Deckert M (1996), Deckert M (1996), Deckert M (1996), Song JS (1996), Bertagnolo V (2001), Bertagnolo V (2001), Tartare-Deckert S (2001)	7
SYK	3	SH3BP2	4	two hybrid, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
SHB	4	LCP2	0	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
ABL1	9	CBLB	3	affinity chromatography technology	Brehme M (2009)	1
RAC1	7	ARHGDIB	1	two hybrid	Vinayagam A (2011)	1
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
SH3BP2	4	VAV1	2	affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology	Jevremovic D (2001), Jevremovic D (2001), Le Bras S (2007), GuezGuez A (2010)	4
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
S100B	0	FGFR1	2	affinity chromatography technology, affinity chromatography technology	Riuzzi F (2011), Riuzzi F (2011)	2
INSR	9	PLCG1	6	unspecified method	Liu BA (2012)	1
VAV1	2	TUBB	3	affinity chromatography technology, affinity chromatography technology	Huby RD (1995), Fernandez JA (1999)	2
GRB2	2	SYK	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Saci A (2002), de Castro RO (2012), de Castro RO (2012)	4
SYK	3	LCP2	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
PIK3R1	6	CD28	0	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pages F (1996), Pages F (1996), Alcazar I (2009), Fang D (2001)	4
ACTBL2	0	ACTA2	1	affinity chromatography technology	Huttlin EL (2017)	1
BLNK	2	PLCG2	11	affinity chromatography technology, affinity chromatography technology	Oellerich T (2011), Oellerich T (2011)	2
EGFR	5	LCP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
CD28	0	VAV1	2	affinity chromatography technology	Klasen S (1998)	1
PRKCQ	3	CBL	7	enzymatic study, affinity chromatography technology	Liu Y (1999), Liu Y (1999)	2
FGFR1	2	PLCG2	11	affinity chromatography technology	Vecchione A (2007)	1
ERBB2	6	SLA	2	unspecified method	Jones RB (2006)	1
PTPN6	0	EPOR	3	affinity chromatography technology, pull down	Klingmueller U (1995), Klingmueller U (1995)	2
ABL1	9	EMD	0	enzymatic study	Tifft KE (2009)	1
VAV1	2	SERPINA12	0	affinity chromatography technology	Huttlin EL (2017)	1
PTPN6	0	LCP2	0	pull down, pull down, affinity chromatography technology	Binstadt BA (1998), Mizuno K (1996), Mizuno K (1996)	3
JUN	0	APLP2	2	two hybrid, pull down	Bandyopadhyay S (2010), Miyamoto-Sato E (2010)	2
SYK	3	PAG1	5	pull down	Brdicka T (2000)	1
SIAH1	2	SIAH2	0	affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Depaux A (2006), Depaux A (2006), Depaux A (2006), Huttlin EL (2017)	5
FYN	1	SOCS1	1	pull down	De Sepulveda P (1999)	1
PLCG1	6	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	BLNK	2	unspecified method	Jones RB (2006)	1
TYK2	1	VAV1	2	affinity chromatography technology	Adam L (2000)	1
FGFR1	2	SLA	2	two hybrid	Hu Y (2004)	1
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
GRB2	2	PAG1	5	pull down	Brdicka T (2000)	1
GRB2	2	DOK1	2	affinity chromatography technology	Kepley CL (2004)	1
XRCC5	5	VAV1	2	affinity chromatography technology	Adam L (2000)	1
EZH2	4	KHDRBS1	1	affinity chromatography technology	Cao Q (2014)	1
LAT	0	PLCG2	11	fluorescent resonance energy transfe, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
LCP2	0	PIK3R1	6	two hybrid, affinity chromatography technology	Shim EK (2004), Shim EK (2004)	2
CHEK1	2	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Goudelock DM (2003), Goudelock DM (2003)	2
FGFR1	2	PIK3R1	6	imaging technique, two hybrid, pull down	Chen TC (2014), Hu Y (2004), Shi E (1993)	3
SHB	4	FGFR1	2	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
TEC	2	DOK1	2	affinity chromatography technology, enzymatic study, pull down, enzymatic study	van Dijk TB (2000), van Dijk TB (2000), van Dijk TB (2000), Liang X (2002)	4
FYN	1	JAK2	1	affinity chromatography technology, pull down	Sayeski PP (1999), Sayeski PP (1999)	2
VAV1	2	PALM2-AKAP2	0	affinity chromatography technology	Huttlin EL (2017)	1
JUN	0	ABL1	9	affinity chromatography technology, enzymatic study, affinity chromatography technology	Xie M (2010), Chen C (2008), Chen C (2008)	3
HNRNPK	4	PLCG1	6	affinity chromatography technology	Huttlin EL (2017)	1
SUZ12	0	XRCC5	5	affinity chromatography technology	Cao Q (2014)	1
RAC1	7	TEC	2	genetic interference	Kline JB (2001)	1
ZAP70	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Nel AE (1995), Jin HS (2013)	2
VAV1	2	DNAJC1	2	affinity chromatography technology	Huttlin EL (2017)	1
VAV1	2	SBSN	1	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	SYK	3	unspecified method	Jones RB (2006)	1
PTK2B	6	VAV1	2	pull down	Katagiri T (2000)	1
CD5	1	FYN	1	affinity chromatography technology	Bamberger M (2011)	1
PDGFRB	8	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Farooqui T (2000), Chamberlain MD (2004), Ren SY (2005), Huttlin EL (2017)	4
CBL	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Erdreich-Epstein A (1999), Chu J (1998), Shen M (2009)	4
PRLR	0	TEC	2	affinity chromatography technology, affinity chromatography technology, pull down	Kline JB (2001), Kline JB (2001), Kline JB (2001)	3
PRLR	0	JAK2	1	affinity chromatography technology, affinity chromatography technology	Pezet A (1997), Ma L (2010)	2
IL6ST	0	ERBB3	3	affinity chromatography technology	Grant SL (2002)	1
GRB2	2	PDGFRB	8	pull down, pull down, affinity chromatography technology	Arvidsson AK (1994), Tang J (1997), Braverman LE (1999)	3
APBB2	2	TUBA1A	13	affinity chromatography technology	Huttlin EL (2015)	1
XRCC6	3	ABL1	9	affinity chromatography technology, affinity chromatography technology	Kumaravel TS (1998), So J (2015)	2
EMD	0	XRCC6	3	affinity chromatography technology	Fogeron ML (2013)	1
GRB2	2	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
BTK	1	CBLB	3	affinity chromatography technology	Yasuda T (2002)	1
SLA	2	PDGFRB	8	affinity chromatography technology	Sirvent A (2008)	1
ERBB3	3	VAV1	2	unspecified method	Jones RB (2006)	1
SYK	3	LAT	0	enzymatic study	Paz PE (2001)	1
VAV1	2	ACTA2	1	affinity chromatography technology	Huttlin EL (2017)	1
EED	1	RAC1	7	affinity chromatography technology	Cao Q (2014)	1
LAT	0	LCP2	0	affinity chromatography technology	Xie JJ (2013)	1
EGFR	5	SOCS1	1	affinity chromatography technology	Xia L (2002)	1
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
MAP2K1	8	RAF1	3	pull down, pull down, pull down, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Yeung K (2000), Yeung K (2000), Dasgupta P (2004), Dasgupta P (2004), Dasgupta P (2004), Boussiotis VA (1997), Kilili GK (2010), Kubota Y (2011), Madonna S (2008), Takekawa M (2005), Gloeckner CJ (2007), Zhu J (2005), Zhu J (2005), Blaukat A (2000), Wang J (2009), Hein MY (2015), Mitra S (2016)	17
PTPN6	0	TYK2	1	affinity chromatography technology, enzymatic study	Yetter A (1995), Yetter A (1995)	2
ZAP70	5	FYN	1	genetic interference, affinity chromatography technology	Neumeister EN (1995), Neumeister EN (1995)	2
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
VAV1	2	SERPINB2	0	affinity chromatography technology	Huttlin EL (2017)	1
BTK	1	VAV1	2	affinity chromatography technology	Guinamard R (1997)	1
ZAP70	5	PAG1	5	pull down	Brdicka T (2000)	1
HNRNPK	4	CBLB	3	pull down	Bustelo XR (1997)	1
CD28	0	DOK1	2	affinity chromatography technology	Klasen S (1998)	1
EPOR	3	PLCG1	6	protein complementation assay	Montoye T (2005)	1
PRKCQ	3	FYN	1	pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999), Ron D (1999)	7
VAV1	2	MAP2K1	8	affinity chromatography technology	Song JS (1996)	1
PLCG1	6	SYK	3	affinity chromatography technology	Sidorenko SP (1995)	1
BLNK	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fu C (1998), Engels N (2001), Fusaki N (2000), Wienands J (1998), Oellerich T (2011), Oellerich T (2011)	6
ABL1	9	ERBB3	3	unspecified method	Jones RB (2006)	1
VAV1	2	ATP2B2	10	affinity chromatography technology	Huttlin EL (2017)	1
RAC1	7	GRB2	2	affinity chromatography technology	Huttlin EL (2017)	1
JAK2	1	EZH2	4	enzymatic study	Sahasrabuddhe AA (2014)	1
BTK	1	FYN	1	pull down	Cheng G (1994)	1
SH3BP2	4	GRB2	2	pull down	Deckert M (1998)	1
PRLR	0	VAV1	2	pull down, affinity chromatography technology, affinity chromatography technology	Kline JB (2001), Clevenger CV (1995), Clevenger CV (1995)	3
CBLB	3	SYK	3	affinity chromatography technology, enzymatic study	Elly C (1999), Wirnsberger G (2016)	2
PIK3R1	6	ZAP70	5	affinity chromatography technology	Moon KD (2005)	1
NOTCH1	25	XRCC6	3	two hybrid	Stelzl U (2005)	1