PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ELOC	0	ELOB	1	two hybrid, pull down, pull down, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, pull down, two hybrid, biochemical, biochemical, two hybrid	Rual JF (2005), Ohh M (1999), Aso T (1995), Li Z (2002), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Lievens S (2009), Brower CS (1999), Stebbins CE (1999), Pause A (1999), Pause A (1999), Havugimana PC (2012), Wang X (2013), Kristensen AR (2012), Costessi A (2011), Rolland T (2014), Kim DY (2013), Wan C (2015), Yu H (2011)	21
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
VHL	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Yao P (2013), Yao P (2013)	3
ELAVL1	0	HIF1AN	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RBX1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Ohta T (2001), Saiga T (2009), Rodier G (2008), Zhou W (2014), Zhou W (2014)	6
VHL	0	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid	Lai Y (2011), Lai Y (2011), Duan DR (1995), Minervini G (2015)	4
VHL	0	VBP1	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Tsuchiya H (1996), Zhou MI (2002), Tsuchiya H (1996), Xu Y (2013)	4
HNRNPL	3	EP300	36	affinity chromatography technology	Fei T (2017)	1
AKT1	1	NR4A1	4	affinity chromatography technology, enzymatic study	Pekarsky Y (2001), Pekarsky Y (2001)	2
PRKCD	2	SP1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai PF (2011), Tsai PF (2011), Tsai PF (2011), Ito H (2012), Xu K (2009), Xu K (2009)	6
HIF1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chew EH (2007), Sufan RI (2006), Luo W (2010), Heir P (2013), Russell RC (2008)	5
VHL	0	PRKCD	2	fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Iturrioz X (2006), Iturrioz X (2006), Yong HJ (2017), Yong HJ (2017)	4
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
FN1	17	TCP1	0	affinity chromatography technology	Humphries JD (2009)	1
CSNK2A1	15	CARD9	3	affinity chromatography technology, enzymatic study	Yang H (2007), Yang H (2007)	2
SP1	0	PRKCZ	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang Y (2006), Zhang Y (2006), Tan NY (2008)	3
VHL	0	USP9X	15	affinity chromatography technology, affinity chromatography technology, pull down	Zhang C (2016), Zhang C (2016), Zhang C (2016)	3
RBX1	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Dias DC (2002), Ohta T (1999), Ohta T (1999), Maine GN (2007), Hu J (2004), Furukawa M (2002), Mao X (2011), Sufan RI (2006), Sufan RI (2006), Sufan RI (2006), Brower CS (2002), Tron AE (2012), Kamura T (2004), Kristensen AR (2012), Costessi A (2011), Huang DT (2009), Kamura T (1999), Kamura T (1999), Xu J (2015), Cardote TAF (2017)	20
RACK1	2	ELOB	1	pull down	Liu YV (2007)	1
RHOBTB3	1	VHL	0	affinity chromatography technology, pull down, two hybrid	Zhang CS (2015), Zhang CS (2015), Zhang CS (2015)	3
VHL	0	PLD1	5	affinity chromatography technology, pull down, pull down	Park MH (2014), Park MH (2014), Park MH (2014)	3
VHL	0	CARD9	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Yang H (2007), Yang H (2007), Yang H (2007), Yang H (2007)	4
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
HNRNPL	3	LIMD1	4	affinity chromatography technology	Fei T (2017)	1
PSMC3	0	HIF1A	1	affinity chromatography technology	Corn PG (2003)	1
VHL	0	USP20	3	affinity chromatography technology, two hybrid, pull down, enzymatic study	Li Z (2002), Li Z (2002), Li Z (2002), Li Z (2002)	4
UXT	0	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
EPAS1	6	EGLN1	3	pull down, pull down, two hybrid, affinity chromatography technology, pull down	Percy MJ (2006), Furlow PW (2009), Aprelikova O (2009), Steunou AL (2012), Barth S (2007)	5
ELAVL1	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Abdelmohsen K (2009), Datta K (2005), Datta K (2005), Yuen JS (2007)	4
VHL	0	AR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen S (2013), Chen S (2013), Wang J (2014), Wang J (2014)	4
OSR1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoo YG (2006), Huang LE (2002), Kageyama Y (2004)	3
SKP2	2	AR	3	imaging technique, affinity chromatography technology	Li B (2014), Li B (2014)	2
EPOR	3	ELOC	0	pull down	Heir P (2016)	1
CUL2	3	HNRNPA2B1	2	affinity chromatography technology	Bennett EJ (2010)	1
VHL	0	EGLN1	3	affinity chromatography technology, affinity chromatography technology, pull down	Foxler DE (2012), Zhang CS (2015), Zhang CS (2015)	3
SP1	0	AR	3	affinity chromatography technology, affinity chromatography technology	Yuan H (2005), Chen PH (2008)	2
UBE2S	2	VHL	0	pull down, pull down, enzymatic study, affinity chromatography technology	Lim JH (2016), Lim JH (2016), Lim JH (2016), Lim JH (2016)	4
HIF1A	1	RBX1	2	affinity chromatography technology	Heir P (2013)	1
EP300	36	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji W (2014), Ianari A (2004), Aoki I (2012)	3
RPS3	0	RPS6	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
AURKA	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL2	3	HNRNPD	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Xin H (2011)	2
HIF1AN	0	ELOB	1	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	DGKZ	6	affinity chromatography technology, affinity chromatography technology, pull down	Tanaka T (2013), Tanaka T (2013), Tanaka T (2013)	3
ELAVL1	0	CSNK2A1	15	affinity chromatography technology	Abdelmohsen K (2009)	1
VHL	0	PLD2	1	affinity chromatography technology, pull down, pull down	Park MH (2015), Park MH (2015), Park MH (2015)	3
SP1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Won J (2002), Zhang Y (2002), Sun JM (2002), Glasspool RM (2005), Duan H (2005), Sekhavat A (2007), Itoh Y (2007), Marshall GM (2010), Tsai PF (2011), Schnur N (2007)	10
PDCD5	0	TP53	0	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Xu L (2012), Xu L (2012), Xu L (2012), Xu L (2012), Park SY (2015)	5
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
VHL	0	RPS3A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Zhao WT (2013), Zhao WT (2013)	3
RACK1	2	ELOC	0	affinity chromatography technology, pull down, affinity chromatography technology	Subauste MC (2009), Liu YV (2007), Liu YV (2007)	3
CSNK2A1	15	5430	0	enzymatic study, affinity chromatography technology	Moisan A (2004), Basnet H (2014)	2
CDKN2A	1	E2F1	0	affinity chromatography technology, pull down	Eymin B (2001), Eymin B (2001)	2
CSNK2A1	15	AKT1	1	enzymatic study	Di Maira G (2005)	1
PSMC3	0	AR	3	affinity chromatography technology, affinity chromatography technology	Satoh T (2009), Satoh T (2009)	2
AURKA	1	HDAC2	1	pull down	Pugacheva EN (2007)	1
EP300	36	5430	0	affinity chromatography technology, affinity chromatography technology	Cho H (1998), Fousteri M (2006)	2
5430	0	EGLN1	3	affinity chromatography technology	Mikhaylova O (2008)	1
CDKN2A	1	HIF1A	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Fatyol K (2001), Fatyol K (2001), Ivanov AA (2017)	3
CDKN2A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Zhang Y (2003), Zhang Y (2003), Rizos H (2003), Zhang Y (1998), Zhang Y (1998), Li L (2010), Li L (2010), Kamijo T (1998), Stott FJ (1998), Ivanov AA (2017)	10
PRKCZ	5	PIAS4	5	two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study	Heo KS (2011), Heo KS (2011), Lear T (2016), Lear T (2016)	4
VHL	0	EPOR	3	affinity chromatography technology, affinity chromatography technology, pull down	Heir P (2016), Heir P (2016), Heir P (2016)	3
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
VHL	0	PDCD5	0	affinity chromatography technology, two hybrid, affinity chromatography technology	Essers PB (2014), Essers PB (2014), Essers PB (2014)	3
RBX1	2	ELOC	0	affinity chromatography technology	Brower CS (2002)	1
CSNK2A1	15	HDAC2	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, biochemical, enzymatic study, biochemical	Sun JM (2002), Sun JM (2007), Adenuga D (2010), Tsai SC (2002), Havugimana PC (2012), Zhang M (2011), Wan C (2015)	7
CSNK2A1	15	VHL	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Lolkema MP (2005), Lolkema MP (2005), Yang H (2007)	3
EGLN1	3	PLD2	1	affinity chromatography technology, affinity chromatography technology	Park MH (2015), Park MH (2015)	2
AR	3	E2F1	0	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
AURKA	1	RPS3A	1	affinity chromatography technology	Fogeron ML (2013)	1
VHL	0	ELOB	1	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Ohh M (1999), Min JH (2002), Hacker KE (2008), Menon S (2008), Kamura T (2002), Kamura T (2002), Kuznetsova AV (2003), Cockman ME (2000), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Kinoshita K (2007), Lai Y (2012), Mahrour N (2008), Mahrour N (2008), Grosfeld A (2007), Foxler DE (2012), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017)	43
HIF1AN	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
MKNK2	1	RBX1	2	two hybrid	Wang P (2006)	1
CEP68	2	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yin H (2017), Yin H (2017), Yin H (2017), Yin H (2017), Kong L (2017)	5
ELAVL1	0	HNRNPA2B1	2	biochemical	Wan C (2015)	1
ID2	0	ELOC	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Lee SB (2016), Lee SB (2016), Lee SB (2016), Lee SB (2016)	4
TP53	0	PIAS4	5	two hybrid	Goehler H (2004)	1
AKT1	1	JADE1	6	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Zeng L (2013), Zeng L (2013), Zeng L (2013), Zeng L (2013)	4
NR4A1	4	HNRNPA2B1	2	two hybrid	Vinayagam A (2011)	1
HIF1A	1	RACK1	2	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baek JH (2007), Liu YV (2007), Liu YV (2007), Liu YV (2007), Sun H (2013), Amir S (2009), Kuo YC (2015), Lee SH (2015)	8
HIF1AN	0	VHL	0	pull down, pull down, pull down	Mahon PC (2001), Mahon PC (2001), Sakamoto T (2009)	3
HNRNPD	3	HNRNPL	3	biochemical	Havugimana PC (2012)	1
UXT	0	AR	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Markus SM (2002), Markus SM (2002), Markus SM (2002), Mita P (2011), Chen S (2013), Chen S (2013)	6
VHL	0	ELOC	0	affinity chromatography technology, pull down, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Tsuchiya H (1996), Min JH (2002), Li Z (2002), Hacker KE (2008), Kim BY (2008), Baek JH (2007), Baek JH (2007), Kuznetsova AV (2003), Cockman ME (2000), Lisztwan J (1999), Stickle NH (2004), Lai Y (2011), Liu YV (2007), Norman JA (2006), Kinoshita K (2007), Cai Q (2010), Lai Y (2012), Miller F (2005), Mahrour N (2008), Mahrour N (2008), Russell RC (2011), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Stebbins CE (1999), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	48
RACK1	2	RPS6	1	biochemical	Marques N (2013)	1
HNRNPA2B1	2	CSNK2A1	15	affinity chromatography technology, enzymatic study, pull down, enzymatic study	Pancetti F (1999), Pancetti F (1999), Pancetti F (1999), Zhang M (2011)	4
HNRNPD	3	HNRNPA2B1	2	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Hein MY (2015)	3
SP1	0	EPAS1	6	affinity chromatography technology, affinity chromatography technology	Koizume S (2012), Koizume S (2012)	2
CDKN2A	1	SP1	0	affinity chromatography technology, affinity chromatography technology	Li DQ (2011), Li DQ (2011)	2
CDKN2A	1	FN1	17	two hybrid	Wang J (2011)	1
CUL2	3	AR	3	affinity chromatography technology	Chen S (2013)	1
USP20	3	USP33	1	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
FN1	17	PDCD5	0	affinity chromatography technology	Humphries JD (2009)	1
AKT1	1	FASN	15	two hybrid	Arroyo R (2015)	1
PIAS4	5	HDAC2	1	pull down	Gross M (2004)	1
RACK1	2	RPS3	0	biochemical	Kristensen AR (2012)	1
FN1	17	FASN	15	affinity chromatography technology	Humphries JD (2009)	1
FN1	17	HNRNPL	3	affinity chromatography technology	Humphries JD (2009)	1
OSR1	1	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Yoo YG (2006), Kageyama Y (2004)	2
CDKN2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL2	3	5430	0	affinity chromatography technology	Bennett EJ (2010)	1
HIF1A	1	FN1	17	affinity chromatography technology	Hein MY (2015)	1
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
PLD1	5	HIF1A	1	affinity chromatography technology, pull down	Park MH (2014), Park MH (2014)	2
CUL2	3	E2F1	0	affinity chromatography technology, pull down	Xu J (2016), Xu J (2016)	2
VHL	0	COL4A1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Grosfeld A (2007), Grosfeld A (2007)	3
AURKA	1	CSNK2A1	15	affinity chromatography technology	Fogeron ML (2013)	1
ELAVL1	0	5430	0	affinity chromatography technology	Abdelmohsen K (2009)	1
VHL	0	COL4A2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Grosfeld A (2007), Grosfeld A (2007)	3
ZNF350	1	EP300	36	affinity chromatography technology	Chen K (2015)	1
TPT1	1	TP53	0	affinity chromatography technology	Amson R (2011)	1
TP53	0	RBX1	2	affinity chromatography technology	Fogeron ML (2013)	1
HNRNPA2B1	2	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pioli PA (2001), Lai Y (2011), Yao P (2013), Liu Y (2016), Liu Y (2016)	5
RACK1	2	RPS3A	1	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
VHL	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Lai Y (2011), Chung J (2006), Kim DS (2011), Minervini G (2015)	4
VHL	0	RPS3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Lai Y (2011), Zhao WT (2013), Zhao WT (2013), Zhao WT (2013)	4
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
VHL	0	AURKA	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Martin B (2013), Martin B (2013), Hasanov E (2017), Hasanov E (2017), Hasanov E (2017)	5
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
ELAVL1	0	HDAC2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
PLD2	1	PRKCD	2	affinity chromatography technology, pull down	Han JM (2002), Han JM (2002)	2
FN1	17	HNRNPA2B1	2	affinity chromatography technology	Humphries JD (2009)	1
EP300	36	EPAS1	6	pull down, affinity chromatography technology, affinity chromatography technology	Kung AL (2004), Steunou AL (2012), Chen R (2012)	3
LIMD1	4	EGLN1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foxler DE (2012), Foxler DE (2012), Zhang CS (2015)	3
HIF1A	1	USP20	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Li Z (2005), Li Z (2005), Li Z (2005)	3
TP53	0	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Borellini F (1993), Jin W (2008), Dhar SK (2006), Lagger G (2003), Lagger G (2003), Lagger G (2003), Lagger G (2003), Sengupta S (2005), Sengupta S (2005), Lin RK (2010), Kim HA (2011), Sawaya BE (1998), St Clair S (2004), Innocente SA (2005), Innocente SA (2005), Ohlsson C (1998), Kong X (2013), Bocangel D (2009), Bocangel D (2009)	19
AURKA	1	HNRNPA2B1	2	affinity chromatography technology	Fogeron ML (2013)	1
VHL	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Kohroki J (2005), Kamura T (2002), Kuznetsova AV (2003), Norman JA (2006), Knauth K (2006), Kamura T (2004), Heir P (2013), Essers PB (2014), Lee SB (2016)	10
VHL	0	SP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Yuen JS (2007), Mukhopadhyay D (1997), Mukhopadhyay D (1997)	3
CERKL	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Chen J (2015), Chen J (2015), Chen J (2015)	3
VHL	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Kamura T (2001), Hacker KE (2008), Hacker KE (2008), Menon S (2008), Chew EH (2007), Ietta F (2006), Megumi Y (2005), Kamura T (2002), Kuznetsova AV (2003), Hansen WJ (2002), Cockman ME (2000), Lisztwan J (1999), Lisztwan J (1999), Sufan RI (2006), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Knauth K (2006), Lonergan KM (1998), Lai Y (2012), Miller F (2005), Mahrour N (2008), Grosfeld A (2007), Russell RC (2011), Foxler DE (2012), Bonicalzi ME (2001), Bennett EJ (2010), Kanaya K (2002), Liakopoulos D (1999), Pause A (1997), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Pause A (1999), Pause A (1999), Xin H (2011), Kamura T (2004), Kamura T (2004), Heir P (2013), Russell RC (2008), Russell RC (2008), Essers PB (2014), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Heir P (2016), Chen K (2016), Uematsu K (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	54
PLD2	1	HIF1A	1	affinity chromatography technology, affinity chromatography technology, pull down	Park MH (2015), Park MH (2015), Park MH (2015)	3
VHL	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, far western blotting, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, protein complementation assay, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Corn PG (2003), Li Z (2003), Mahon PC (2001), Tanimoto K (2000), Min JH (2002), Yu F (2001), Yu F (2001), Jung JE (2008), Jung JE (2008), Andre H (2008), Park YK (2008), Kim BY (2008), Park SS (2008), Baek JH (2007), Baek JH (2007), Baek JH (2007), Kondo S (2006), Ietta F (2006), Kwon SJ (2005), Bae MK (2005), Baek JH (2005), Hon WC (2002), Hon WC (2002), Lewis MD (2004), Kasuno K (2004), Metzen E (2003), Metzen E (2003), Zhou J (2003), Yuan Y (2003), Maynard MA (2003), Jeong JW (2002), Yoo YG (2008), Hansen WJ (2002), Masson N (2001), Masson N (2001), Clifford SC (2001), Jaakkola P (2001), Jaakkola P (2001), Kamura T (2000), Kamura T (2000), Kamura T (2000), Ohh M (2000), Ohh M (2000), Cockman ME (2000), Cockman ME (2000), Sufan RI (2006), Chang CC (2011), Sufan RI (2009), Stickle NH (2004), Luo W (2010), Lee HY (2011), Roe JS (2011), Ivan M (2001), Ivan M (2001), Huang LE (2002), Callapina M (2005), Callapina M (2005), Maranchie JK (2002), DAngelo G (2003), DAngelo G (2003), Miller F (2005), Grosfeld A (2007), Grosfeld A (2007), Rajakumar A (2008), Bonicalzi ME (2001), Bemis L (2004), Berra E (2001), Yu F (2001), Bex C (2007), Zhou J (2012), Wiesener MS (2002), Maxwell PH (1999), Maxwell PH (1999), Lee SH (2012), Lee SH (2012), Ivan M (2002), Aprelikova O (2009), Choi CY (2009), Choi CY (2009), Heir P (2013), Russell RC (2008), Russell RC (2008), Park JH (2011), Park JH (2011), Liu Q (2013), Yeh IJ (2013), Choi YK (2010), Yang F (2014), Yang F (2014), Yang F (2014), Parsanejad M (2014), Yang C (2013), Yang C (2013), Chen K (2013), Park MH (2014), Gerez J (2015), Hein MY (2015), Park MH (2015), Fu R (2016), Alahari S (2015), Zhang CS (2015), Song D (2013), Chen K (2016), Hicks KC (2016), Groulx I (2002), Groulx I (2002), Groulx I (2002), Huttlin EL (2017), Guo J (2016), Sun W (2017), Sun W (2017), Guo J (2016), Li YM (2005), Yoo YG (2004), Kimura M (2008), Ferrer CM (2014)	116
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
AURKA	1	RPS3	0	affinity chromatography technology	Fogeron ML (2013)	1
5430	0	POLR2G	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
TP53	0	TCP1	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
PSMC3	0	TP53	0	affinity chromatography technology	Kulikov R (2010)	1
AKT1	1	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Guo J (2016), Guo J (2016)	2
RWDD3	1	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Carbia-Nagashima A (2007), Gerez J (2015)	2
VHL	0	RWDD3	1	affinity chromatography technology, affinity chromatography technology, pull down	Gerez J (2015), Gerez J (2015), Gerez J (2015)	3
VHL	0	USP33	1	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, enzymatic study	Li Z (2002), Li Z (2002), Li Z (2002), Yuasa-Kawada J (2009), Yuasa-Kawada J (2009), Li Z (2002)	6
NR4A1	4	TP53	0	affinity chromatography technology, pull down, pull down	Zhao BX (2006), Zhao BX (2006), Zhao BX (2006)	3
HDAC2	1	VHL	0	pull down, affinity chromatography technology, genetic interference	Mahon PC (2001), Hwang IY (2012), Shen JP (2017)	3
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
ELAVL1	0	SKP2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	HIF1A	1	affinity chromatography technology, unspecified method	Galban S (2008), Galban S (2008)	2
ELAVL1	0	MKNK2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
PSMC3	0	EPAS1	6	affinity chromatography technology	Corn PG (2003)	1
HIF1A	1	NR4A1	4	affinity chromatography technology, affinity chromatography technology	Kim BY (2008), Kim BY (2008)	2
CUL2	3	ELOB	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kamura T (2001), Menon S (2008), Megumi Y (2005), Kamura T (2002), Brower CS (2002), Bennett EJ (2010), Pause A (1997), Kamura T (2004), Kelsall IR (2013)	9
HNRNPL	3	PIAS4	5	affinity chromatography technology	Fei T (2017)	1
FN1	17	HNRNPD	3	affinity chromatography technology	Humphries JD (2009)	1
VHL	0	DGKI	2	two hybrid, two hybrid, affinity chromatography technology	Bex C (2007), Bex C (2007), Bex C (2007)	3
VHL	0	LIMD1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Foxler DE (2012), Foxler DE (2012), Zhang CS (2015), Zhang CS (2015)	4
FN1	17	RACK1	2	affinity chromatography technology	Humphries JD (2009)	1
VHL	0	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology	Ji W (2014), Ji W (2014), Ji W (2014)	3
ELAVL1	0	RACK1	2	biochemical	Wan C (2015)	1
VHL	0	PSMC3	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Corn PG (2003), Corn PG (2003), Corn PG (2003)	3
AURKA	1	USP9X	15	affinity chromatography technology	Fogeron ML (2013)	1
CSNK2A1	15	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study	Uhle S (2003), Fogeron ML (2013), Bhansali M (2014), Chen TC (2014), Walerych D (2004), Walerych D (2004)	6
NR4A1	4	EP300	36	pull down, enzymatic study	Wansa KD (2002), Kang SA (2010)	2
UXT	0	VHL	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chen S (2013), Chen S (2013), Chen S (2013), Chen S (2013), Chen S (2013)	5
RPS6	1	VHL	0	affinity chromatography technology, affinity chromatography technology, biochemical	Zhao WT (2013), Zhao WT (2013), Zhao WT (2013)	3
HDAC2	1	HIF1A	1	pull down, imaging technique	Mahon PC (2001), Chen TC (2014)	2
FN1	17	RPS6	1	affinity chromatography technology	Humphries JD (2009)	1
RHOBTB3	1	EGLN1	3	affinity chromatography technology, affinity chromatography technology	Zhang CS (2015), Zhang CS (2015)	2
VHL	0	TCP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lai Y (2011), Grosfeld A (2007), Feldman DE (2003), Feldman DE (2003), Yang C (2013)	5
NR4A1	4	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Kim BY (2008), Kim BY (2008), Kim BY (2008)	3
PSMC3	0	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Pollice A (2007), Pollice A (2007), Pollice A (2004), Pollice A (2004), Pollice A (2004)	5
CSNK2A1	15	HNRNPL	3	enzymatic study	Zhang M (2011)	1
EPOR	3	CUL2	3	affinity chromatography technology	Heir P (2016)	1
ELAVL1	0	HNRNPL	3	affinity chromatography technology	Abdelmohsen K (2009)	1
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
FN1	17	RPS3A	1	affinity chromatography technology	Humphries JD (2009)	1
VHL	0	EPAS1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Khacho M (2008), Kuznetsova AV (2003), Clifford SC (2001), Ohh M (2000), Cockman ME (2000), Cockman ME (2000), Ivan M (2001), Miller F (2005), Grosfeld A (2007), Russell RC (2011), Bex C (2007), Maxwell PH (1999), Maxwell PH (1999), Heir P (2013), Gerez J (2015), Luo J (2015), Luo F (2016), Sun W (2017)	18
RPS3	0	TP53	0	fluorescent resonance energy transfe	Yadavilli S (2009)	1
CUL2	3	RPS3A	1	affinity chromatography technology	Bennett EJ (2010)	1
HIF1A	1	ELOB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Luo W (2010), Heir P (2013), Russell RC (2008)	3
RHOBTB3	1	RBX1	2	affinity chromatography technology, pull down	Lu A (2013), Lu A (2013)	2
CUL2	3	ELOC	0	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kamura T (2001), Maine GN (2007), Megumi Y (2005), Mao X (2009), Lonergan KM (1998), Lonergan KM (1998), Bennett EJ (2010), Pause A (1997), Pause A (1999), Kamura T (2004), Kelsall IR (2013), Lee SB (2016)	12
SKP2	2	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Roe JS (2011), Roe JS (2011), Roe JS (2011)	3
HNRNPL	3	PRKCZ	5	affinity chromatography technology	Fei T (2017)	1
VHL	0	HNRNPD	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down	Lai Y (2011), Xin H (2011), Xin H (2011), Xin H (2011), Xin H (2011), Xin H (2011)	6
VHL	0	TPT1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Chen K (2013), Chen K (2013), Chen K (2013)	4
VHL	0	FASN	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Sun W (2017), Sun W (2017), Sun W (2017), Sun W (2017)	4
ELOB	1	USP33	1	affinity chromatography technology	Yuasa-Kawada J (2009)	1
VHL	0	POLR2G	0	two hybrid, pull down, affinity chromatography technology	Na X (2003), Na X (2003), Na X (2003)	3
MKNK2	1	VHL	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Wang P (2006), Wang P (2006), Wang P (2006)	3
TP53	0	AURKA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, genetic interference, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Katayama H (2004), Katayama H (2004), Katayama H (2004), Katayama H (2004), Hsueh KW (2013), Huttlin EL (2015), Huttlin EL (2017)	12
ELAVL1	0	USP33	1	affinity chromatography technology	Abdelmohsen K (2009)	1
PRKCD	2	ELAVL1	0	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Doller A (2007), Doller A (2008), Doller A (2008), Doller A (2011), Doller A (2011), Doller A (2010)	6
HNRNPL	3	AR	3	affinity chromatography technology	Fei T (2017)	1
EP300	36	HNRNPA2B1	2	affinity chromatography technology, affinity chromatography technology	Xuan Y (2016), Xuan Y (2016)	2
HIF1A	1	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baek JH (2007), Hubbi ME (2011), Liu YV (2007), Luo W (2010), Liu YV (2007), Russell RC (2008)	6
AR	3	TP53	0	genetic interference	Shenk JL (2001)	1
AR	3	RACK1	2	two hybrid, affinity chromatography technology, pull down	Rigas AC (2003), Rigas AC (2003), Rigas AC (2003)	3
EPAS1	6	HIF1A	1	affinity chromatography technology	Steunou AL (2012)	1
VHL	0	ZNF350	1	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Chen K (2015), Chen K (2015), Chen K (2015), Chen K (2015)	4
FN1	17	ELAVL1	0	affinity chromatography technology	Humphries JD (2009)	1
VHL	0	5430	0	affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Mikhaylova O (2008), Kuznetsova AV (2003), Kuznetsova AV (2003), Sun W (2017)	4
SKP2	2	ELOC	0	affinity chromatography technology	Kimura Y (2007)	1
CUL2	3	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
RACK1	2	CUL2	3	affinity chromatography technology	Zhang W (2008)	1
PRKCD	2	EP300	36	enzymatic study	Yuan LW (2000)	1
ELAVL1	0	PIAS4	5	affinity chromatography technology	Abdelmohsen K (2009)	1
MKNK2	1	VBP1	0	two hybrid	Wang P (2006)	1
CUL2	3	RPS6	1	affinity chromatography technology	Bennett EJ (2010)	1
PIAS4	5	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Cai Q (2010), Cai Q (2010), Chien W (2013), Chien W (2013), Cai Q (2010)	5
TP53	0	HDAC2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li P (2010), Insinga A (2004), Sun JM (2007), Tian B (2011), Adenuga D (2010), Brandl A (2012)	6
VHL	0	RACK1	2	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	He X (2011), He X (2011), He X (2011), He X (2011)	4
HIF1A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
USP9X	15	TCP1	0	biochemical	Kristensen AR (2012)	1
TP53	0	HNRNPA2B1	2	affinity chromatography technology	Fogeron ML (2013)	1
HIF1AN	0	HIF1A	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Mahon PC (2001), Mahon PC (2001), Mahon PC (2001), Luo W (2010), Liu YV (2007), Lee YM (2009), Lee YM (2009), Lee YM (2009), Hewitson KS (2002), Li SH (2008), Sakamoto T (2009), Rodriguez J (2016)	12
CDKN2A	1	HNRNPA2B1	2	pull down	Souza-Rodrigues E (2007)	1
PRKCD	2	TP53	0	affinity chromatography technology	Lee SJ (2006)	1
HIF1A	1	ZNF197	0	affinity chromatography technology	Li Z (2003)	1
DGKZ	6	VHL	0	imaging technique, affinity chromatography technology, affinity chromatography technology	Iturrioz X (2007), Iturrioz X (2007), Iturrioz X (2007)	3
HIF1A	1	EGLN1	3	pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Percy MJ (2006), Baek JH (2005), Yoo YG (2008), Chowdhury R (2009), Choi YK (2010), Park MH (2014), Park MH (2015), Park MH (2015), Barth S (2007), Song D (2013), Guo J (2016), Kumar P (2015)	12
EPOR	3	ELOB	1	pull down	Heir P (2016)	1
RHOBTB3	1	LIMD1	4	affinity chromatography technology, affinity chromatography technology	Zhang CS (2015), Zhang CS (2015)	2
RPS3A	1	RPS6	1	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
AR	3	PIAS4	5	pull down, pull down	Gross M (2001), Gross M (2004)	2
HDAC2	1	HIF1AN	0	pull down	Mahon PC (2001)	1
ELAVL1	0	EPAS1	6	affinity chromatography technology	Abdelmohsen K (2009)	1
VHL	0	ZNF197	0	two hybrid, pull down, affinity chromatography technology	Li Z (2003), Li Z (2003), Li Z (2003)	3
HIF1AN	0	PSMC3	0	affinity chromatography technology	Rodriguez J (2016)	1
ELOB	1	RBX1	2	affinity chromatography technology, affinity chromatography technology	Kamura T (2002), Brower CS (2002)	2
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EP300	36	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015)	5
AURKA	1	CDKN2A	1	affinity chromatography technology	Ewing RM (2007)	1
CUL2	3	CDKN2A	1	affinity chromatography technology	Bennett EJ (2010)	1
SP1	0	SKP2	2	affinity chromatography technology	Tapias A (2008)	1
TP53	0	RPS3A	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
FN1	17	CSNK2A1	15	affinity chromatography technology	Humphries JD (2009)	1
TP53	0	RPS6	1	affinity chromatography technology	Fogeron ML (2013)	1
EP300	36	HIF1A	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Lando D (2002), Freedman SJ (2002), Lewis MD (2004), Matt T (2004), Sang N (2002), Luo W (2010), Freedman SJ (2003), Bodily JM (2011), Lee YM (2009), Lee YM (2009), Lee YM (2009), Kung AL (2004), Kung AL (2004), Kung AL (2004), Land SC (2007), Zhang Y (2010), Zhang Y (2010), Fath DM (2006), Fath DM (2006), Lee SJ (2013), Wang D (2014), Kaluz S (2006), Kaluz S (2006), Kaluz S (2006), Shin DH (2008), Shin DH (2008), Wang Y (2012), Huang C (2009), Hewitson KS (2002), Cook KM (2009), Cook KM (2009), Hubbi ME (2012), Kim SY (2014), Sang N (2003), Sang N (2003), Sang N (2003), Yasinska IM (2003), Na YR (2013), Na YR (2013), Mendonca DB (2011), Arany Z (1996), Arany Z (1996), Chen R (2012), Li SH (2008), Galbraith MD (2013), Chen Z (2014), Li Q (2012), Geng H (2012), Geng H (2012), Kato H (2004), Lim JH (2010), Kyle HF (2015), Kyle HF (2015), Rath S (2016), Kimura M (2008), Dubey R (2013)	56
AURKA	1	LIMD1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGLN1	3	PLD1	5	affinity chromatography technology, pull down, affinity chromatography technology	Park MH (2014), Park MH (2014), Park MH (2014)	3
RPS3A	1	RPS3	0	biochemical, biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	3
HNRNPA2B1	2	HNRNPL	3	affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Hamilton BJ (1999), Havugimana PC (2012), Yao P (2013), Yao P (2013), Yao P (2013), Fei T (2017)	6
CSNK2A1	15	RPS3	0	enzymatic study, enzymatic study	Zhang M (2011), Yang HJ (2013)	2
UBE2S	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Hu L (2017), Hu L (2017), Hu L (2017)	3
VHL	0	JADE1	6	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Zhou MI (2002), Zhou MI (2002), Zhou MI (2004), Zhou MI (2004)	4
HIF1AN	0	ELOC	0	affinity chromatography technology	Rodriguez J (2016)	1
RACK1	2	EPOR	3	pull down	Usacheva A (2003)	1
SKP2	2	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Marti A (1999), Zhang Z (2005), Farhana L (2002), Salon C (2007), Swarnalatha M (2013)	6
ELOC	0	USP33	1	pull down, affinity chromatography technology	Li Z (2002), Yuasa-Kawada J (2009)	2
VHL	0	DNAJA3	2	pull down, affinity chromatography technology, affinity chromatography technology	Bae MK (2005), Bae MK (2005), Lai Y (2011)	3
FASN	15	HIF1A	1	affinity chromatography technology	Sun W (2017)	1
AURKA	1	HNRNPD	3	biochemical	Wan C (2015)	1
HIF1A	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
VHL	0	PRKCZ	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okuda H (1999), Okuda H (1999), Schermer B (2006)	3
VHL	0	FN1	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohh M (1998), Stickle NH (2004), Lai Y (2011), Bonicalzi ME (2001), Iliopoulos O (1998), Russell RC (2008)	6
PRKCZ	5	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Doornbos RP (1999), Wang J (2008), Wang J (2008), Joshi J (2008), Joshi J (2008)	5
ELAVL1	0	RBX1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
COL4A2	2	COL4A1	9	x-ray crystallography	Than ME (2002)	1
VHL	0	CLU	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Xue J (2012), Xue J (2012), Xue J (2012), Xue J (2012)	4
MKNK2	1	CUL2	3	two hybrid	Wang P (2006)	1
EPAS1	6	ELOB	1	affinity chromatography technology	Steunou AL (2012)	1
CUL2	3	RPS3	0	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	RPS3	0	affinity chromatography technology	Humphries JD (2009)	1
RPS3	0	TCP1	0	biochemical	Havugimana PC (2012)	1
ID2	0	VHL	0	pull down, affinity chromatography technology, affinity chromatography technology	Lee SB (2016), Lee SB (2016), Lee SB (2016)	3
HNRNPL	3	HIF1A	1	affinity chromatography technology	Fei T (2017)	1
E2F1	0	SP1	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down	Lin SY (1996), Lin SY (1996), Rotheneder H (1999), Rotheneder H (1999), Karlseder J (1996), Karlseder J (1996), Doetzlhofer A (1999)	7
SP1	0	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	To KK (2006), To KK (2006), Sanchez-Elsner T (2002), Sanchez-Elsner T (2002), Koshiji M (2005), Koshiji M (2005)	6
RHOBTB3	1	HIF1A	1	affinity chromatography technology	Zhang CS (2015)	1