Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
XPA	rs1800975	CC	Platinum compounds	efficacy	yes	Only significant within the squamous cell carcinoma subtype patients (i.e. not significant in overall cohort of non-small-cell lung cancer patients with stage IIIA/IIIB or stage IV). Platinum-based doublets consisting of cisplatin or carboplatin plus gemcitabine, vinorelbine, taxane or pemetrexed. Response defined as complete or partial response; non-response defined as stable disease or progression disease. Please note alleles have been complemented to the plus chromosomal strand.	Genotype CC is associated with increased response to Platinum compounds in people with Carcinoma, Non-Small-Cell Lung as compared to genotypes CT + TT.	25069034	1296667190