PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
EGFR	5	RASA1	3	pull down, unspecified method, pull down	Daly RJ (1996), Jones RB (2006), Marengere LE (1992)	3
SIT1	1	ZAP70	5	affinity chromatography technology	Marie-Cardine A (1999)	1
USP2	0	EGFR	5	affinity chromatography technology	Kim J (2012)	1
TUBA1A	13	TUBB	3	biochemical, biochemical, pull down	Havugimana PC (2012), Kristensen AR (2012), Wang W (2014)	3
LCK	0	PAG1	5	pull down	Brdicka T (2000)	1
SLA	2	ZAP70	5	affinity chromatography technology	Tang J (1999)	1
CD5	1	PTPN6	0	affinity chromatography technology	Perez-Villar JJ (1999)	1
CD4	1	ZAP70	5	affinity chromatography technology	Thome M (1995)	1
SLA	2	VAV1	2	affinity chromatography technology, pull down	Sosinowski T (2000), Sosinowski T (2000)	2
CBLB	3	VAV1	2	affinity chromatography technology, two hybrid, pull down, far western blotting, affinity chromatography technology	Sattler M (2002), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997)	5
CD5	1	RASA1	3	affinity chromatography technology	Dennehy KM (1998)	1
CSK	3	RASA1	3	pull down	Neet K (1995)	1
EGFR	5	SLA	2	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
ASB3	0	ZAP70	5	two hybrid	Wang J (2011)	1
SIT1	1	FYN	1	affinity chromatography technology	Marie-Cardine A (1999)	1
SH3BP2	4	CBL	7	pull down, affinity chromatography technology	Deckert M (1998), GuezGuez A (2010)	2
CBL	7	TUBB	3	affinity chromatography technology, affinity chromatography technology	Teckchandani AM (2005), Brehme M (2009)	2
SHB	4	ABL1	9	affinity chromatography technology, affinity chromatography technology, pull down	Haegerkvist R (2007), Haegerkvist R (2007), Haegerkvist R (2007)	3
CD3E	0	LCK	0	affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003)	2
PTPN22	3	CD247	1	affinity chromatography technology	Wu J (2006)	1
SHB	4	LAT	0	affinity chromatography technology, affinity chromatography technology	Lindholm CK (1999), Lindholm CK (2002)	2
PTPN22	3	GRB2	2	affinity chromatography technology	Hill RJ (2002)	1
LCP2	0	APP	1	pull down	Olah J (2011)	1
SH3BP2	4	PLCG1	6	pull down, far western blotting	Deckert M (1998), Jevremovic D (2001)	2
LCP2	0	PAG1	5	pull down	Brdicka T (2000)	1
USP12	1	APP	1	pull down	Olah J (2011)	1
USP2	0	CBLC	1	two hybrid	Hayes SD (2012)	1
VAV1	2	PAG1	5	pull down	Brdicka T (2000)	1
CBL	7	HSPA4	3	affinity chromatography technology	Valiya Veettil M (2011)	1
VAV1	2	LCP2	0	affinity chromatography technology, pull down, affinity chromatography technology	Raab M (1997), Onodera H (1996), Shen M (2009)	3
ABL1	9	PLCG1	6	pull down	Koch A (2000)	1
CBL	7	ABL1	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, far western blotting, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Soubeyran P (2003), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Patel H (2006), Johnson KJ (2009), Shishido T (2000), Shishido T (2000), Shishido T (2000), Gaston I (2004), Jain SK (1997), Reedquist KA (1996), Bhat A (1997), Bhat A (1997), Bhat A (1997), Grossmann AH (2004), Brehme M (2009), Brehme M (2009), Brehme M (2009), Nishihara T (2003), Tsukahara F (2010)	21
VAV1	2	ABL1	9	pull down, two hybrid, affinity chromatography technology, enzymatic study	Bassermann F (2002), Bassermann F (2002), Bassermann F (2002), Bassermann F (2002)	4
PTPN6	0	LAT	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016), Matalon O (2016)	3
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
CSK	3	SHC1	0	pull down, affinity chromatography technology	Sato K (2002), Brehme M (2009)	2
ZAP70	5	CD5	1	affinity chromatography technology	Gary-Gouy H (1997)	1
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
EGFR	5	ACP1	4	affinity chromatography technology	Tong J (2014)	1
NDUFB8	0	ZAP70	5	two hybrid	Wang J (2011)	1
ZAP70	5	TYROBP	0	unspecified method	Lanier LL (1998)	1
VAV1	2	CD5	1	biochemical	Roa NS (2013)	1
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
ERBB3	3	TUBB	3	affinity chromatography technology	Li J (2013)	1
PLCG1	6	LAT	0	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Zhang W (1998), Paz PE (2001), Paz PE (2001), Zhang W (1998), Jiang Y (2007), Braiman A (2006), Braiman A (2006), Matalon O (2016), Matalon O (2016)	9
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
ERBB3	3	SHC1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Li J (2013), Hellyer NJ (2001)	5
ZAP70	5	APP	1	pull down	Olah J (2011)	1
CBLC	1	EGFR	5	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, x-ray crystallography	Kim M (1999), Keane MM (1999), Keane MM (1999), Takeshita K (2012), Takeshita K (2012), Takeshita K (2012)	6
ZAP70	5	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
CSK	3	CD3E	0	pull down	Catipovic B (1996)	1
USP12	1	GRB2	2	bioid	Jahan AS (2016)	1
DBNL	2	ZAP70	5	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Han J (2003), Han J (2003), Han J (2003), Han J (2003)	4
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
SHB	4	ZAP70	5	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
CD3E	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	de Aos I (1997), Alcazar I (2009)	2
CBLB	3	LCK	0	affinity chromatography technology	Kumar S (2011)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
SHC1	0	APP	1	pull down, affinity chromatography technology	Tarr PE (2002), Tarr PE (2002)	2
TUBA1B	0	CD247	1	affinity chromatography technology	Serrador JM (2004)	1
CBL	7	PLCG1	6	far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Tvorogov D (2002), Tvorogov D (2002), Tvorogov D (2002), Graham LJ (1998), Singh AJ (2007), Rellahan BL (2003), Rellahan BL (2003), Okabe S (2006), Choi JH (2003), Choi JH (2003), Braiman A (2006), Braiman A (2006), Braiman A (2006), Chen TC (2014)	14
SHC1	0	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
LAT	0	PIK3R1	6	affinity chromatography technology, pull down	Paz PE (2001), Paz PE (2001)	2
TUBA1A	13	TUBA1B	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
USP12	1	LAT	0	bioid	Jahan AS (2016)	1
VAV1	2	PTPN6	0	pull down	Kon-Kozlowski M (1996)	1
PLCG1	6	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
PTPN22	3	LCK	0	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
PLCG1	6	RASA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jabado N (1998), Jabado N (1997), Jabado N (1997)	3
RASA1	3	ABL1	9	affinity chromatography technology	Druker B (1992)	1
LAT	0	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Paz PE (2001), Zhang W (1998), Perez-Villar JJ (2002), Motto DG (1994), Houtman JC (2006)	5
ABL1	9	PTPN6	0	affinity chromatography technology	Kharbanda S (1996)	1
ERBB3	3	CRK	0	unspecified method	Jones RB (2006)	1
LCK	0	LAT	0	biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Jiang Y (2007), Jiang Y (2007)	4
SHB	4	PLCG1	6	affinity chromatography technology	Lindholm CK (1999)	1
CD38	0	CD247	1	affinity chromatography technology, biochemical	Munoz P (2003), Munoz P (2003)	2
ZAP70	5	HSPA4	3	affinity chromatography technology	Loewenberg M (2006)	1
EGFR	5	TUBB	3	affinity chromatography technology	Foerster S (2013)	1
CBLC	1	CRK	0	pull down, two hybrid	Keane MM (1999), Grossmann A (2015)	2
SHC1	0	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Puil L (1994), Brehme M (2009), Brehme M (2009), Brehme M (2009)	5
SHC1	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
ABL1	9	PAG1	5	two hybrid, affinity chromatography technology	Wen ST (1997), Wen ST (1997)	2
CBLB	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Zhang Z (1999), Kumar S (2011)	2
PTPN22	3	CSK	3	bioid, affinity chromatography technology	St-Denis N (2016), Li X (2016)	2
SH3BP2	4	ZAP70	5	affinity chromatography technology, pull down	Deckert M (1998), Deckert M (1998)	2
CD247	1	RNF41	2	affinity chromatography technology, affinity chromatography technology	Yang M (2015), Yang M (2015)	2
CBLC	1	FYN	1	affinity chromatography technology, pull down	Kim M (1999), Kim M (1999)	2
CBL	7	ZAP70	5	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography	Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017)	11
VAV1	2	EGFR	5	affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Moores SL (2000), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	4
VAV1	2	ZAP70	5	pull down, affinity chromatography technology	Katzav S (1994), Huby RD (1995)	2
VAV1	2	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Bertagnolo V (1998), Bertagnolo V (1998), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
SH3BP2	4	LAT	0	pull down, affinity chromatography technology	Deckert M (1998), Jevremovic D (2001)	2
SHB	4	PIK3R1	6	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
USP12	1	ZAP70	5	bioid	Jahan AS (2016)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
FYN	1	SH3BP2	4	two hybrid	Deckert M (1998)	1
GAB2	3	CD247	1	affinity chromatography technology	Yamasaki S (2001)	1
PTPN22	3	CBL	7	affinity chromatography technology	Cohen S (1999)	1
TUBA1B	0	ZAP70	5	affinity chromatography technology	Serrador JM (2004)	1
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
ZAP70	5	ABL1	9	affinity chromatography technology	Neumeister EN (1995)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
LAT	0	CBL	7	affinity chromatography technology	Jiang Y (2007)	1
ZAP70	5	LCP2	0	enzymatic study, enzymatic study	Raab M (1997), Kim KS (2002)	2
EGFR	5	CSK	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
CD4	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Hawash IY (2002), Foti M (2002), Bernhard OK (2004), Loewenberg M (2006), Py B (2007)	5
ZAP70	5	ACP1	4	affinity chromatography technology	Bottini N (2002)	1
SLA	2	LAT	0	affinity chromatography technology	Tang J (1999)	1
LAT	0	VAV1	2	pull down, pull down, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Perez-Villar JJ (2002)	3
ABL1	9	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, enzymatic study, two hybrid, enzymatic study	Brehme M (2009), Brehme M (2009), Brehme M (2009), Peterson ME (2008), Yoshida K (2005), Chen C (2008), Feller SM (1994), Feller SM (1994), Bai RY (1998), Ren J (2002)	10
ERBB3	3	CSK	3	affinity chromatography technology	Schulze WX (2006)	1
CD4	1	TUBB	3	affinity chromatography technology	Bernhard OK (2004)	1
VAV1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
NR0B2	1	ZAP70	5	two hybrid	Wang J (2011)	1
CBLB	3	SHC1	0	affinity chromatography technology	Lavagna-Sevenier C (1998)	1
ABL1	9	EGFR	5	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
FCRL3	2	PTPN6	0	affinity chromatography technology, pull down	Xu MJ (2002), Xu MJ (2002)	2
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
PTPN6	0	PAG1	5	pull down	Brdicka T (2000)	1
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
CSK	3	FYN	1	affinity chromatography technology	Takeuchi M (1993)	1
ZAP70	5	PTPN6	0	pull down	Plas DR (1996)	1
TUBA1B	0	TUBB	3	biochemical	Havugimana PC (2012)	1
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
TUBA1A	13	CBL	7	affinity chromatography technology	Teckchandani AM (2005)	1
CBL	7	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Bertagnolo V (2001), Miura-Shimura Y (2003), Simmons A (2005), Shen M (2009), Shen M (2009), Lottin-Divoux S (2006), Lottin-Divoux S (2006), Peterson ME (2008)	12
USP2	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
LCK	0	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pelosi M (1999), Thome M (1995), Lupher ML (1996)	3
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
VAV1	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song JS (1996), Ye ZS (1994), Ye ZS (1994), Germani A (1999), Lee IS (1997)	5
CBLC	1	SHC1	0	two hybrid	Vinayagam A (2011)	1
CD5	1	LCK	0	affinity chromatography technology	Bamberger M (2011)	1
EGFR	5	ZAP70	5	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
CRK	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
SHB	4	VAV1	2	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
CD247	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Yang M (2015)	3
SH3BP2	4	DBNL	2	two hybrid, affinity chromatography technology	Le Bras S (2007), Le Bras S (2007)	2
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
HSPA4	3	APP	1	affinity chromatography technology	Kumar P (2007)	1
SHC1	0	PLCG1	6	affinity chromatography technology	Fixman ED (1996)	1
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
GAB2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down	Lynch DK (2002), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Ren SY (2005), Momose H (2003)	6
DBNL	2	CBL	7	affinity chromatography technology	Le Bras S (2007)	1
GRB2	2	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid	Lewitzky M (2001), Robinson A (1996), Erdreich-Epstein A (1999), Hendricks-Taylor LR (1997), Asada H (1999), Bandyopadhyay S (2010), Chu J (1998), Berry DM (2002), Brehme M (2009), Rolland T (2014)	10
ZAP70	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, pull down	Nel AE (1995), Braiman A (2006), Hubert P (1996)	3
PLCG1	6	GAB2	3	pull down	Zhao C (1999)	1
ZAP70	5	LAT	0	enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Houtman JC (2006), Xie JJ (2013)	4
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
SHC1	0	TUBA1B	0	affinity chromatography technology	Brehme M (2009)	1
SHC1	0	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Lynch DK (2002), van den Akker E (2004)	3
RNF41	2	ZAP70	5	affinity chromatography technology, pull down	Yang M (2015), Yang M (2015)	2
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
CSK	3	ZAP70	5	pull down	Catipovic B (1996)	1
ZAP70	5	RASA1	3	affinity chromatography technology	Neumeister EN (1995)	1
CD38	0	ZAP70	5	biochemical	Munoz P (2003)	1
ZAP70	5	TUBB	3	affinity chromatography technology	Huby RD (1995)	1
RASA1	3	APP	1	pull down	Olah J (2011)	1
PTPN22	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
PTPN22	3	VAV1	2	affinity chromatography technology	Wu J (2006)	1
PTPN6	0	LCK	0	enzymatic study, enzymatic study, pull down	Yu CL (2000), Chiang GG (2001), Lorenz U (1994)	3
FYN	1	PAG1	5	pull down, affinity chromatography technology	Brdicka T (2000), Brdicka T (2000)	2
CD247	1	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mustelin T (1995), Wang HY (2001), La Face DM (1997), Huang H (2010), Huang H (2010), Hubert P (1996), Yang M (2015)	7
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
ZAP70	5	SHC1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Pacini S (1998), Pacini S (1998), Jin HS (2013)	3
ERBB3	3	ZAP70	5	unspecified method	Jones RB (2006)	1
PIK3R1	6	TUBA1B	0	affinity chromatography technology, pull down	Kapeller R (1995), Kapeller R (1995)	2
ABL1	9	GRB2	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Warmuth M (1997), Ren R (1994), Ren R (1994), Patel H (2006), Johnson KJ (2009), Gaston I (2004), Gaston I (2004), Brehme M (2009), Brehme M (2009), Chen R (2013), Feller SM (1994)	11
EGFR	5	TUBA1A	13	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
VAV1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bertagnolo V (1998), Bertagnolo V (1998), Bertagnolo V (1998), Shigematsu H (1997), Shigematsu H (1997), Shigematsu H (1997)	6
ZAP70	5	CD3E	0	pull down, affinity chromatography technology	Bu JY (1995), Hubert P (1996)	2
SHC1	0	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Ota S (1998), Larsson H (1999)	4
PIK3R1	6	CD247	1	affinity chromatography technology	Fang D (2001)	1
FYN	1	VAV1	2	affinity chromatography technology, two hybrid	Michel F (1998), Tartare-Deckert S (2001)	2
FCRL3	2	ZAP70	5	pull down	Xu MJ (2002)	1
SLA2	1	ZAP70	5	affinity chromatography technology	Pandey A (2002)	1
CBL	7	SLA	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang J (1999), Myers MD (2006), Sirvent A (2008), Swaminathan G (2007)	4
EGFR	5	LAT	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PEAR1	5	ZAP70	5	affinity chromatography technology	Scheib JL (2012)	1
CD5	1	CBL	7	affinity chromatography technology, biochemical	Dennehy KM (1998), Roa NS (2013)	2
CRK	0	SHB	4	affinity chromatography technology	Lu L (2000)	1
FYN	1	LAT	0	enzymatic study	Jiang Y (2007)	1
EGFR	5	PTPN22	3	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
SHB	4	GRB2	2	affinity chromatography technology	Welsh M (1998)	1
ABL1	9	PIK3R1	6	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Kapeller R (1994), Ren SY (2005), Ren SY (2005), Ren SY (2005), Brehme M (2009)	5
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
ZAP70	5	ZAP70	5	affinity chromatography technology	Hubert P (1996)	1
CSK	3	PAG1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brdicka T (2000), Brdicka T (2000), Vang T (2003), Vang T (2003), Huttlin EL (2017)	5
LCP2	0	PLCG1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Yablonski D (2001), Yablonski D (2001), Braiman A (2006), Braiman A (2006), Braiman A (2006)	5
EGFR	5	SLA2	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PTPN22	3	CD3E	0	affinity chromatography technology, affinity chromatography technology	Wu J (2006), Wu J (2006)	2
SHB	4	LCP2	0	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
ABL1	9	CBLB	3	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
SLA	2	CD247	1	affinity chromatography technology	Tang J (1999)	1
CRK	0	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
CBLC	1	ZAP70	5	unspecified method	Takeshita K (2012)	1
SH3BP2	4	VAV1	2	affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology	Jevremovic D (2001), Jevremovic D (2001), Le Bras S (2007), GuezGuez A (2010)	4
ABL1	9	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Bali P (2005), Wu LX (2006)	2
RASA1	3	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB3	3	TUBA1B	0	affinity chromatography technology	Li J (2013)	1
GRB2	2	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2004), Lynch DK (2002), Zhao C (1999), Zhao C (1999), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Rolland T (2014), Huttlin EL (2017), Yu WM (2006), Yu WM (2006)	11
VAV1	2	TUBB	3	affinity chromatography technology, affinity chromatography technology	Huby RD (1995), Fernandez JA (1999)	2
CD3E	0	CD247	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Munoz P (2003), Munoz P (2003), Chen TC (2014)	3
GRB2	2	RASA1	3	affinity chromatography technology	Lamprecht R (2002)	1
EGFR	5	LCP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
CD38	0	LCK	0	affinity chromatography technology	Munoz P (2003)	1
PTPN6	0	LCP2	0	pull down, pull down, affinity chromatography technology	Binstadt BA (1998), Mizuno K (1996), Mizuno K (1996)	3
LCP2	0	SHC1	0	affinity chromatography technology	Chu J (1998)	1
PLCG1	6	ERBB3	3	unspecified method	Jones RB (2006)	1
CD38	0	CD3E	0	affinity chromatography technology, biochemical	Munoz P (2003), Munoz P (2003)	2
GAB2	3	PTPN6	0	affinity chromatography technology	Yu WM (2002)	1
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
GRB2	2	PAG1	5	pull down	Brdicka T (2000)	1
CBL	7	CD247	1	affinity chromatography technology, affinity chromatography technology	Wang HY (2001), Wang HY (2001)	2
LCP2	0	PIK3R1	6	two hybrid, affinity chromatography technology	Shim EK (2004), Shim EK (2004)	2
RNF41	2	APP	1	pull down	Olah J (2011)	1
SLA2	1	CD247	1	affinity chromatography technology	Pandey A (2002)	1
TUBB	3	APP	1	pull down	Olah J (2011)	1
ZAP70	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Nel AE (1995), Jin HS (2013)	2
GAB2	3	LAT	0	affinity chromatography technology	Yamasaki S (2001)	1
LAT	0	CD247	1	affinity chromatography technology	Munoz P (2003)	1
CD5	1	FYN	1	affinity chromatography technology	Bamberger M (2011)	1
CBL	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Erdreich-Epstein A (1999), Chu J (1998), Shen M (2009)	4
CRK	0	CBLB	3	affinity chromatography technology, two hybrid, two hybrid	Brehme M (2009), Grossmann A (2015), Grossmann A (2015)	3
HSPA4	3	TUBB	3	biochemical	Wan C (2015)	1
CRK	0	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
GRB2	2	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
USP12	1	CBLB	3	bioid	Jahan AS (2016)	1
CBL	7	CD38	0	fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Shen M (2009), Shen M (2008), Shen M (2008)	3
ERBB3	3	VAV1	2	unspecified method	Jones RB (2006)	1
ANAPC11	0	ZAP70	5	two hybrid	Wang J (2011)	1
SIT1	1	LCK	0	affinity chromatography technology	Marie-Cardine A (1999)	1
SLA2	1	CBL	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pandey A (2002), Pandey A (2002), Pakuts B (2007), Pakuts B (2007), Holland SJ (2001), Manes GA (2006), Loreto MP (2003), Loreto MP (2003)	8
USP2	0	ZAP70	5	enzymatic study	Naik E (2016)	1
LAT	0	LCP2	0	affinity chromatography technology	Xie JJ (2013)	1
GAB2	3	ZAP70	5	affinity chromatography technology	Yamasaki S (2001)	1
SHC1	0	PAG1	5	pull down	Brdicka T (2000)	1
CBL	7	CSK	3	affinity chromatography technology, affinity chromatography technology	Sanjay A (2001), Brehme M (2009)	2
ZAP70	5	FYN	1	genetic interference, affinity chromatography technology	Neumeister EN (1995), Neumeister EN (1995)	2
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
ZAP70	5	PAG1	5	pull down	Brdicka T (2000)	1
CSK	3	CD247	1	pull down, affinity chromatography technology	Catipovic B (1996), Catipovic B (1996)	2
LAT	0	CD3E	0	affinity chromatography technology	Munoz P (2003)	1
ABL1	9	ERBB3	3	unspecified method	Jones RB (2006)	1
RNF41	2	ERBB3	3	pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Diamonti AJ (2002), Qiu XB (2002), Qiu XB (2002), Fry WH (2011), Fry WH (2011), Bouyain S (2007), Hatakeyama J (2016)	7
GRB2	2	CSK	3	affinity chromatography technology	Bisson N (2011)	1
SH3BP2	4	GRB2	2	pull down	Deckert M (1998)	1
CRK	0	ZAP70	5	pull down	Gelkop S (1999)	1
LCK	0	RASA1	3	enzymatic study	Giglione C (2001)	1
PIK3R1	6	ZAP70	5	affinity chromatography technology	Moon KD (2005)	1