PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SIRT7	1	HIST2H2AC	1	pull down	Ford E (2006)	1
TMPO	0	HUWE1	22	affinity chromatography technology	Brady GF (2018)	1
APC	5	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, genetic interference	Homma MK (2002), Homma MK (2002), Homma MK (2002), Chen TC (2014), Srivas R (2016)	5
CRY1	0	USP11	3	affinity chromatography technology	Papp SJ (2015)	1
EED	1	BMI1	0	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014)	4
PML	7	DAXX	5	two hybrid, two hybrid, affinity chromatography technology, imaging technique, two hybrid, affinity chromatography technology, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique	Ishov AM (1999), Li H (2000), Li H (2000), Li H (2000), Lehembre F (2001), Zhong S (2000), Cuchet-Lourenco D (2011), Chu Y (2011), Meinecke I (2007), Jang MS (2002), Chang CC (2011), Wethkamp N (2011), Ferguson BJ (2007), Delbarre E (2013), Delbarre E (2013), Sahin U (2014), Lin DY (2006), Lin DY (2006), Lin DY (2006), Lin DY (2006), Torii S (1999)	21
UHRF2	1	TP53	0	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011)	4
USP7	14	CLSPN	1	affinity chromatography technology, enzymatic study	Faustrup H (2009), Faustrup H (2009)	2
YAF2	1	23429	0	affinity chromatography technology	Huttlin EL (2017)	1
CTNNB1	30	PPARG	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zurlo D (2014), Zurlo D (2014), Jansson EA (2005), Jiang Y (2009)	4
SIRT7	1	CSNK2A1	15	affinity chromatography technology	Tsai YC (2012)	1
SIRT7	1	ANXA1	1	affinity chromatography technology	Tsai YC (2012)	1
USP7	14	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study	Sowa ME (2009), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Du Z (2010), Du Z (2010), Du Z (2010), Du Z (2010), Ma H (2012), Hein MY (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015)	19
CSNK2A1	15	MDM2	2	enzymatic study, enzymatic study	Goetz C (1999), Hjerrild M (2001)	2
MYC	2	POLH	1	genetic interference	Toyoshima M (2012)	1
TRAF6	0	UBC	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Muroi M (2011), Park S (2013), Sun L (2004), Kanayama A (2004), Sakamoto H (2015), Yu J (2016), Middleton AJ (2017)	7
USP7	14	WWP2	7	two hybrid, affinity chromatography technology	Lim J (2006), Chaudhary N (2014)	2
USP7	14	RAE1	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009)	2
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
MDM2	2	PHF7	5	two hybrid	Woodsmith J (2012)	1
ABL1	9	HUWE1	22	enzymatic study	Gu J (1994)	1
MBD4	1	TRIM27	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid	Fukushige S (2006), Fukushige S (2006), Fukushige S (2006), Fukushige S (2006), Yu H (2011)	5
EED	1	NCL	1	affinity chromatography technology	Cao Q (2014)	1
CSNK2A1	15	RING1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	So J (2015), Hauri S (2016), Hauri S (2016)	3
ANXA1	1	RELA	1	affinity chromatography technology	Bist P (2011)	1
RELA	1	TP53	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Huang WC (2007), Huang WC (2007), Ivanov AA (2017)	3
SOX2	4	GLI3	10	affinity chromatography technology	Cox JL (2013)	1
BRCA1	7	AR	3	pull down, pull down, two hybrid	Park JJ (2000), Yeh S (2000), Yeh S (2000)	3
IKBKG	0	PHF7	5	pull down	Fenner BJ (2010)	1
TRIM27	2	DAXX	5	affinity chromatography technology	Chen A (2006)	1
USP11	3	UBC	7	enzymatic study, pull down, pull down	Faesen AC (2011), Zhang X (2017), Kwasna D (2018)	3
USP7	14	HIST2H2AC	1	affinity chromatography technology, enzymatic study	Lecona E (2015), Yu M (2016)	2
HUWE1	22	OGT	4	affinity chromatography technology, affinity chromatography technology	Thompson JW (2014), Hein MY (2015)	2
OGT	4	CSNK2A1	15	enzymatic study, enzymatic study	Lazarus BD (2006), Lubas WA (2000)	2
CBX8	3	NCL	1	affinity chromatography technology	Vandamme J (2011)	1
SIRT7	1	HUWE1	22	affinity chromatography technology	Tsai YC (2012)	1
FOXO3	1	USP7	14	affinity chromatography technology, affinity chromatography technology	van der Horst A (2006), Bucur O (2014)	2
MYC	2	RBPJ	1	affinity chromatography technology	Agrawal P (2010)	1
GMPS	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Reddy BA (2014), Reddy BA (2014)	2
IKBKG	0	PPP2CA	7	affinity chromatography technology	Kray AE (2005)	1
DNMT1	5	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Fuks F (2003), Esteve PO (2006)	2
MYC	2	NCL	1	affinity chromatography technology	Koch HB (2007)	1
RNF2	1	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Cao Q (2014), Gao Z (2014), Hauri S (2016), Hauri S (2016)	5
PKM	1	CTNNB1	30	affinity chromatography technology, pull down	Liang J (2016), Liang J (2016)	2
PML	7	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down	Alcalay M (1998), Alcalay M (1998), Alcalay M (1998)	3
USP7	14	CCDC6	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Morra F (2015)	2
SMAD3	1	SUV39H1	0	affinity chromatography technology	Wakabayashi Y (2011)	1
BMI1	0	AR	3	affinity chromatography technology	Cao Q (2014)	1
EED	1	CBX8	3	affinity chromatography technology	Cao Q (2014)	1
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
SIRT7	1	DNMT1	5	affinity chromatography technology	Tsai YC (2012)	1
USP7	14	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014)	4
KAT5	1	AR	3	enzymatic study, two hybrid, two hybrid, pull down, two hybrid, pull down	Gaughan L (2002), Gaughan L (2002), Brady ME (1999), Brady ME (1999), Gaughan L (2001), Gaughan L (2001)	6
ATXN1	2	UHRF2	1	two hybrid	Suter B (2013)	1
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
MDM2	2	23429	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chen D (2009), Chen D (2009), Chen D (2009), Chen D (2009)	4
UHRF1	3	DNMT1	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Achour M (2008), Achour M (2008), Achour M (2008), Achour M (2008), Jin W (2010), Achour M (2009), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Du Z (2010), Du Z (2010), Zhang J (2011), Bostick M (2007), Bostick M (2007), Hervouet E (2010), Hervouet E (2010), Bashtrykov P (2014), De Vos M (2014), De Vos M (2014), Qin W (2015), Myrianthopoulos V (2016), Fang J (2016), Ferry L (2017)	25
TCEAL1	3	TCEAL4	0	affinity chromatography technology	Sowa ME (2009)	1
TRIP12	20	MYC	2	pull down, affinity chromatography technology	Chen D (2010), Chen D (2010)	2
SIRT7	1	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Tsai YC (2012), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017)	6
UBE2E1	1	RING1	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Markson G (2009), Wheaton K (2017), Wheaton K (2017)	3
APC	5	CTNNB1	30	affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su LK (1993), Su LK (1993), Kucerova D (2001), Tickenbrock L (2003), Davies G (2001), Ryo A (2001), Homma MK (2002), Tickenbrock L (2003), Davies G (2001), Satoh K (1997), Eklof Spink K (2001), Eklof Spink K (2001), Sierra J (2006), Choi J (2004), Huang X (2009), Brocardo MG (2011), Xing Y (2004), Xing Y (2004), Xing Y (2004), Hamada F (2004), Hamada F (2004), Schneikert J (2013), Hsi LC (1999), Hein MY (2015), Hein MY (2015), Chen TC (2014), Kuslansky Y (2016), Novellasdemunt L (2017), Novellasdemunt L (2017)	29
TRIM27	2	KAT5	1	two hybrid	Rolland T (2014)	1
BMI1	0	TP53	0	affinity chromatography technology, affinity chromatography technology	Calao M (2012), Yin J (2013)	2
CHEK1	2	RELA	1	enzymatic study	Rocha S (2005)	1
NOTCH1	25	PHF8	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012), Yatim A (2012)	3
PPARG	0	SMAD3	1	affinity chromatography technology	Lin LC (2011)	1
BRCA1	7	ANXA1	1	affinity chromatography technology	Ertych N (2016)	1
UBC	7	RAE1	0	affinity chromatography technology	Matsumoto M (2005)	1
UBE2E1	1	RELA	1	enzymatic study	Ryo A (2003)	1
ABL1	9	23429	0	two hybrid, far western blotting, pull down	Zhu J (1996), Zhu J (1996), Zhu J (1996)	3
AR	3	SMAD3	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Hayes SA (2001), Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Kang HY (2002), Kang HY (2002), Kang HY (2002), Kang HY (2002), Chipuk JE (2002)	12
BMI1	0	NCL	1	affinity chromatography technology	Cao Q (2014)	1
EED	1	RNF2	1	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Cao Q (2014), Cao Q (2014), Cao Q (2014), Cao Q (2014)	4
ING1	2	UBC	7	pull down	Thalappilly S (2011)	1
USP7	14	UHRF1	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Ma H (2012), Ma H (2012), Ma H (2012), Chen H (2013), Nishiyama A (2013), Hein MY (2015), Zhang ZM (2015), Zhang ZM (2015), Zhang ZM (2015), Pfoh R (2015), Pfoh R (2015), Ferry L (2017)	18
MYC	2	TRRAP	31	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, pull down	Liu X (2003), McMahon SB (2000), McMahon SB (1998), Park J (2002), Bres V (2009), Cowling VH (2006), Frank SR (2001), Kim J (2010), Kim J (2010), Koch HB (2007), Toyoshima M (2012), Liu X (2003)	12
RNF168	0	NCL	1	affinity chromatography technology	Guturi KK (2016)	1
TRAF4	1	WWP2	7	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
MDM2	2	PKM	1	pull down, affinity chromatography technology, pull down, enzymatic study	Miyamoto-Sato E (2010), Riscal R (2016), Riscal R (2016), Riscal R (2016)	4
SIRT7	1	MCM4	3	affinity chromatography technology	Tsai YC (2012)	1
DAXX	5	TP53	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, unspecified method	Tang J (2006), Kim EJ (2003), Kim EJ (2003), Kim EJ (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Ohiro Y (2003), Wethkamp N (2011), Zhao LY (2004), Zhao LY (2004), Zhao LY (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Gostissa M (2004), Zhao LY (2004), Zhao LY (2004), Zhang H (2013), Zhang H (2013), Chen TC (2014), Li Z (2017)	23
PCGF1	1	23429	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Huttlin EL (2015), Oliviero G (2015), Oliviero G (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	11
RELA	1	OGT	4	affinity chromatography technology, affinity chromatography technology	Golks A (2007), Golks A (2007)	2
CBX8	3	KAT5	1	two hybrid, affinity chromatography technology	Stelzl U (2005), Tan J (2011)	2
MDM4	0	UBC	7	enzymatic study	Egorova O (2014)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
HIST2H2AC	1	TCF20	18	pull down	Darvekar S (2012)	1
PTEN	24	UBC	7	protein complementation assay, affinity chromatography technology	Li Y (2014), Li Y (2014)	2
RB1	2	KAT5	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Leduc C (2006), Leduc C (2006), Leduc C (2006)	3
OTUD4	2	UBC	7	enzymatic study, enzymatic study, pull down, pull down	Mevissen TE (2013), Zhao Y (2015), Zhang X (2017), Kwasna D (2018)	4
FBXO38	3	PPM1G	1	two hybrid	Wang J (2011)	1
USP7	14	GLI3	10	affinity chromatography technology, affinity chromatography technology	Zhou Z (2015), Zhou Z (2015)	2
23429	0	RNF2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Cao Q (2014), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	11
TMPO	0	RB1	2	affinity chromatography technology	Markiewicz E (2002)	1
TMPO	0	NCL	1	affinity chromatography technology	Brady GF (2018)	1
USP11	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Maertens GN (2010), Maertens GN (2010), Ma H (2012), Hein MY (2015)	7
TFIP11	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down	Ye M (2015), Ye M (2015), Ye M (2015)	3
CRY1	0	PKM	1	affinity chromatography technology	Papp SJ (2015)	1
RING1	2	23429	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Garcia E (1999), Garcia E (1999), Garcia E (1999), Garcia E (1999), Gearhart MD (2006), Gao Z (2012), Gao Z (2012), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	13
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
TP53	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Palii SS (2008), Zhang H (2013), Zhang H (2013)	3
WWP2	7	UBC	7	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Sheng Y (2012), Maspero E (2013), Soond SM (2013), Kristariyanto YA (2015)	4
UHRF1	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study	Ma J (2015), Ma J (2015), Ma J (2015), Ma J (2015)	4
PKM	1	RELA	1	two hybrid	Wang J (2011)	1
TCEAL4	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hein MY (2015), Hein MY (2015)	3
ABRAXAS2	1	IFNAR1	4	imaging technique	Zheng H (2013)	1
MDM4	0	USP7	14	pull down, x-ray crystallography, unspecified method	Sarkari F (2010), Sarkari F (2010), Sarkari F (2010)	3
PPP2CA	7	CCDC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), St-Denis N (2016), Yadav L (2017)	3
BRCA1	7	RELA	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Benezra M (2003), Benezra M (2003), Benezra M (2003), Volcic M (2012)	4
TRRAP	31	TP53	0	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Ard PG (2002), Ard PG (2002), Ard PG (2002), Gamper AM (2008)	4
POLH	1	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Qian J (2014), Qian J (2014), Qian J (2014), Qian J (2014), Qian J (2014)	5
RNF2	1	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
SOX2	4	USP7	14	affinity chromatography technology, affinity chromatography technology	Cox JL (2013), Cox JL (2013)	2
IFNAR1	4	PKM	1	affinity chromatography technology	Zheng H (2013)	1
CHFR	5	PML	7	fluorescent resonance energy transfe	Daniels MJ (2004)	1
RB1	2	AR	3	pull down, pull down, two hybrid, affinity chromatography technology	Lu J (1998), Yeh S (1998), Yeh S (1998), Gamble SC (2007)	4
PHF8	6	RARA	5	fluorescent resonance energy transfe	Qiu J (2010)	1
PCGF2	3	23429	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Gao Z (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
UBC	7	ABRAXAS2	1	pull down, pull down	Wang B (2009), Nathan JA (2013)	2
POLH	1	BRCA1	7	affinity chromatography technology	Tian F (2013)	1
KIF23	0	PHLDB2	5	affinity chromatography technology	Hein MY (2015)	1
HIST2H2AC	1	UBC	7	pull down, pull down	Long L (2014), Zhang X (2017)	2
BCOR	2	23429	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gao Z (2012), Huttlin EL (2015), Oliviero G (2015), Huttlin EL (2017), Hauri S (2016)	6
GAS2L1	2	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TCEAL1	3	GMPS	1	affinity chromatography technology	Sowa ME (2009)	1
UBC	7	XPC	1	affinity chromatography technology	Bish RA (2007)	1
HUWE1	22	ABRAXAS2	1	biochemical	Kristensen AR (2012)	1
RNF2	1	YAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Cao Q (2014), Hein MY (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
TP53	0	TRIM8	6	affinity chromatography technology	Caratozzolo MF (2012)	1
EED	1	PCGF1	1	affinity chromatography technology	Cao Q (2014)	1
OTUD4	2	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhao Y (2015), Zhao Y (2015), Zhao Y (2015), Zhao Y (2015)	4
FOXO3	1	TRRAP	31	affinity chromatography technology	Li X (2015)	1
TP53	0	TCEAL1	3	affinity chromatography technology	Huttlin EL (2015)	1
WWP2	7	ABRAXAS2	1	affinity chromatography technology	Chaudhary N (2014)	1
TRIM27	2	RB1	2	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kruetzfeldt M (2005), Kruetzfeldt M (2005), Kruetzfeldt M (2005), Kruetzfeldt M (2005), Kruetzfeldt M (2005)	5
RNF2	1	RELA	1	affinity chromatography technology	Cao Q (2014)	1
USP7	14	USP7	14	affinity chromatography technology, unspecified method	Lee HJ (2005), Rouge L (2016)	2
UBC	7	PJA1	1	affinity chromatography technology	Matsumoto M (2005)	1
PCGF1	1	RNF2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gearhart MD (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Woodsmith J (2012), Woodsmith J (2012), Cao Q (2014), Hein MY (2015), Taherbhoy AM (2015), Taherbhoy AM (2015), Oliviero G (2015), Oliviero G (2015), Hauri S (2016), Hauri S (2016)	16
PCGF2	3	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
USP11	3	RAE1	0	affinity chromatography technology	Sowa ME (2009)	1
MDM2	2	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen L (2010), Mungamuri SK (2016), Mungamuri SK (2016)	3
OGT	4	USP7	14	affinity chromatography technology, affinity chromatography technology	Ding X (2015), Ding X (2015)	2
RELA	1	UBC	7	affinity chromatography technology	Schweitzer K (2015)	1
KIF23	0	USP7	14	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
SVIL	9	PPARG	0	two hybrid	Ting HJ (2002)	1
PPARG	0	RB1	2	affinity chromatography technology, pull down, pull down	Fajas L (2002), Fajas L (2002), Fajas L (2002)	3
PJA1	1	USP7	14	enzymatic study, affinity chromatography technology	Loch CM (2012), Huttlin EL (2017)	2
RING1	2	RB1	2	affinity chromatography technology	Dahiya A (2001)	1
TCEAL1	3	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
DAXX	5	USP7	14	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang J (2006), Tang J (2006), Tang J (2006), Tang J (2006), Song MS (2008), Giovinazzi S (2013), Giovinazzi S (2013), Giovinazzi S (2013), Kumar N (2013)	9
PCGF1	1	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Hein MY (2015), Oliviero G (2015), Hauri S (2016)	4
NCL	1	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park JJ (2015), Park JJ (2015), Lim KH (2015), Lim KH (2015)	4
KMT2E	7	TRAF6	0	affinity chromatography technology	Ding X (2015)	1
USP7	14	TRAF6	0	pull down, affinity chromatography technology, enzymatic study	Zapata JM (2001), Daubeuf S (2009), Bremm A (2010)	3
IKBKG	0	ANXA1	1	affinity chromatography technology, biochemical, affinity chromatography technology	Bist P (2011), Bist P (2011), Bist P (2011)	3
UBC	7	OGT	4	pull down	Zhang X (2017)	1
NOTCH1	25	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
TCEAL1	3	UHRF1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AR	3	SVIL	9	two hybrid, pull down, two hybrid	Ting HJ (2002), Ting HJ (2002), Ting HJ (2002)	3
KAT5	1	RBPJ	1	affinity chromatography technology	Kim MY (2007)	1
ATXN1	2	USP7	14	two hybrid, affinity chromatography technology	Hong S (2002), Hong S (2002)	2
PPM1G	1	HIST2H2AC	1	affinity chromatography technology	Yadav L (2017)	1
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
USP7	14	PPM1G	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Sowa ME (2009), St-Denis N (2016), Khoronenkova SV (2012), Khoronenkova SV (2012), Khoronenkova SV (2012)	5
MDM4	0	MDM2	2	pull down, two hybrid, enzymatic study, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, two hybrid, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, two hybrid, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Kadakia M (2002), Tanimura S (1999), Badciong JC (2002), Tanimura S (1999), Tanimura S (1999), Linke K (2008), Okamoto K (2005), Pan Y (2003), Kashuba E (2011), Kashuba E (2011), Ohtsubo C (2009), Singh RK (2007), Zhu Y (2009), Zhu Y (2009), Allende-Vega N (2010), Okamoto K (2009), Okamoto K (2009), Li X (2011), Nie J (2010), Nie J (2010), Li M (2011), Li M (2011), Singh RK (2007), de Graaf P (2003), Wade M (2012), Uldrijan S (2007), Wade M (2012), Stad R (2000), Dolezelova P (2012), Kulikov R (2005), Kawai H (2007), Kawai H (2007), Miller KR (2010), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Sharp DA (1999), Li C (2002), Wu S (2012), Ranaweera RS (2013), Woodsmith J (2012), Wang J (2011), Egorova O (2014), Chang YS (2013), Malbert-Colas L (2014), Yasuhara T (2014), Yasuhara T (2014), Iyappan S (2010), Stad R (2001), Marcar L (2015), Ling X (2014), Leslie PL (2015), Jacob AG (2014), Jacob AG (2014), Tournillon AS (2015), Tournillon AS (2015), Tournillon AS (2015), Zhang H (2015), Chen L (2015), Pellegrino M (2015), Pellegrino M (2015), Pellegrino M (2015), Medina-Medina I (2016), Medina-Medina I (2016), Moscetti I (2016), Liu T (2017), Liu T (2017), Liu T (2017), Huttlin EL (2017), Wu W (2015), Ivanov AA (2017), Mancini F (2016), Mancini F (2016)	74
TCEAL1	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017)	3
RING1	2	TP53	0	affinity chromatography technology	Calao M (2012)	1
MYD88	1	TRAF6	0	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fitzgerald KA (2001), Zhou J (2011), Zhou J (2011), Zhang X (2013), Zhang X (2013), Hirata Y (2006)	6
MDM2	2	RNF2	1	affinity chromatography technology, affinity chromatography technology	Wen W (2013), Wen W (2013)	2
USP7	14	MARCH7	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Lim J (2006), Hayes SD (2012), Nathan JA (2008), Zhang L (2016)	4
RNF169	1	UBE2E1	1	pull down	Poulsen M (2012)	1
CTNNB1	30	ABL1	9	affinity chromatography technology, affinity chromatography technology	Chen R (2013), Chen R (2013)	2
YAF2	1	RING1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Rolland T (2014), Yu H (2011), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
RNF2	1	HIST2H2AC	1	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Wang H (2004), Zaaroor-Regev D (2010), Bentley ML (2011), Li Z (2006), Gearhart MD (2006), Gao Z (2014), Bhatnagar S (2014), Yang XX (2016)	8
USP7	14	RNF168	0	pull down, affinity chromatography technology	Zhu Q (2015), Zhu Q (2015)	2
USP7	14	PKM	1	affinity chromatography technology, affinity chromatography technology	Park JJ (2015), Park JJ (2015)	2
BMI1	0	23429	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Cao Q (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
MBD4	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Meng H (2014), Meng H (2014)	2
BMI1	0	TRAF4	1	affinity chromatography technology	Cao Q (2014)	1
CSNK2A1	15	PLEKHO1	1	two hybrid, pull down, affinity chromatography technology	Bosc DG (2000), Bosc DG (2000), Bosc DG (2000)	3
USP11	3	XPC	1	biochemical	Havugimana PC (2012)	1
BMI1	0	TFIP11	5	affinity chromatography technology	Cao Q (2014)	1
DAXX	5	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), He Q (2015), He Q (2015)	3
MARCH7	0	UBC	7	enzymatic study	Flierman D (2006)	1
SOX2	4	BMI1	0	affinity chromatography technology	Cox JL (2013)	1
CHEK1	2	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference	Yarden RI (2002), Yarden RI (2002), Inoue Y (2007), Shen JP (2017)	4
PHF8	6	RBPJ	1	affinity chromatography technology	Yatim A (2012)	1
PHLDB2	5	USP7	14	two hybrid, affinity chromatography technology	Wang J (2011), Hein MY (2015)	2
SOX2	4	RAE1	0	affinity chromatography technology	Cox JL (2013)	1
USP7	14	TRAF4	1	pull down, affinity chromatography technology, affinity chromatography technology	Zapata JM (2001), Yi P (2013), Yi P (2013)	3
USP7	14	CBX8	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
TCEAL1	3	MCMBP	3	affinity chromatography technology	Huttlin EL (2015)	1
BMI1	0	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010), de Bie P (2010), Lecona E (2015), Lecona E (2015)	6
CHEK1	2	RB1	2	enzymatic study, pull down	Inoue Y (2007), Inoue Y (2007)	2
BRCA1	7	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian F (2013), Tian F (2013), Hill SJ (2014)	3
TFIP11	5	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Ye M (2015), Ye M (2015), Ye M (2015)	3
SIRT7	1	TRIP12	20	affinity chromatography technology	Tsai YC (2012)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
WRAP53	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Sun Y (2017), Sun Y (2017)	2
USP7	14	IFNAR1	4	affinity chromatography technology, affinity chromatography technology, pull down	Yu Y (2017), Yu Y (2017), Yu Y (2017)	3
DAXX	5	UBC	7	two hybrid	Bandyopadhyay S (2010)	1
RING1	2	RNF2	1	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Gearhart MD (2006), Wang H (2004), Trojer P (2011), Gao Z (2012), Gao Z (2012), Cao Q (2014), Hein MY (2015)	8
BRCA1	7	UBE2E1	1	two hybrid, x-ray crystallography, pull down, two hybrid, pull down	Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Christensen DE (2007), David Y (2011)	5
PTEN	24	NOTCH1	25	genetic interference	Vizeacoumar FJ (2013)	1
KAT5	1	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2002), Legube G (2002), Wu Q (2009), Dohmesen C (2008), Dohmesen C (2008), Kim JW (2008)	6
APC	5	USP7	14	affinity chromatography technology, affinity chromatography technology	Novellasdemunt L (2017), Novellasdemunt L (2017)	2
USP7	14	HUWE1	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Thompson JW (2014), Thompson JW (2014), Hein MY (2015)	4
USP11	3	PML	7	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wu HC (2014), Wu HC (2014), Wu HC (2014), Wu HC (2014)	4
CSNK2A1	15	RELA	1	affinity chromatography technology, enzymatic study	Wang D (2000), Wang D (2000)	2
USP7	14	RNF2	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2010), Maertens GN (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), Gao Z (2012), Cao Q (2014), Lecona E (2015), Lecona E (2015), Hein MY (2015)	12
ING1	2	USP7	14	affinity chromatography technology, affinity chromatography technology	Thalappilly S (2011), Thalappilly S (2011)	2
BRCA1	7	KIF23	0	affinity chromatography technology	Ertych N (2016)	1
MDM2	2	RELA	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Heyne K (2013), Heyne K (2013), Heyne K (2013)	4
BRCA1	7	NCL	1	affinity chromatography technology	Ertych N (2016)	1
TPP1	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Zemp I (2014), Zemp I (2014)	2
USP7	14	ABRAXAS2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Zhang J (2014), Zhang J (2014), Zhang J (2014)	4
BMI1	0	RNF2	1	biochemical, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, biochemical, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Cao R (2005), Ben-Saadon R (2006), Li Z (2006), Maertens GN (2009), Wei J (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Pan MR (2011), Pan MR (2011), Voncken JW (2005), Woodsmith J (2012), Voncken JW (2003), Woodsmith J (2012), Li Z (2006), Li Z (2006), McGinty RK (2014), Cao Q (2014), Cao Q (2014), Hein MY (2015), Balasubramanian S (2015), Taherbhoy AM (2015), Taherbhoy AM (2015), Abdouh M (2016), Sanchez A (2016), Wheaton K (2017), Hauri S (2016), Hauri S (2016)	30
YAF2	1	BCOR	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Hein MY (2015), Oliviero G (2015), Huttlin EL (2017), Hauri S (2016)	5
CHEK1	2	PTEN	24	genetic interference	Shen JP (2017)	1
WWP2	7	UBE2E1	1	pull down	Xu H (2009)	1
CSNK2A1	15	CCDC6	3	enzymatic study	Zhang M (2011)	1
SIRT7	1	KIF23	0	affinity chromatography technology	Tsai YC (2012)	1
PPM1G	1	GMPS	1	affinity chromatography technology	St-Denis N (2016)	1
DNMT1	5	TRIM27	2	two hybrid	Stelzl U (2005)	1
TRIM27	2	MDM2	2	affinity chromatography technology, enzymatic study	Chu Y (2011), Chu Y (2011)	2
RELA	1	SMAD3	1	two hybrid	Wang J (2011)	1
UBC	7	ABL1	9	affinity chromatography technology, two hybrid	Chen R (2013), Chen R (2013)	2
RNF168	0	TRIP12	20	affinity chromatography technology	Gudjonsson T (2012)	1
PCGF2	3	YAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Gao Z (2012), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	6
GLI1	3	TP53	0	affinity chromatography technology	Li X (2015)	1
TP53	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li M (2002), Li M (2002), Li M (2002), Li M (2002), Brooks CL (2007), Brooks CL (2007), Becker K (2007), Hu M (2006), Hu M (2006), Sarkari F (2010), Marchenko ND (2007), Epping MT (2011), Qing P (2011), Tang J (2006), Ma J (2010), Dai C (2011), Holowaty MN (2003), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Yi P (2013), Yi P (2013), Zhang J (2014), Fang Z (2013), Ye M (2015), Lim KH (2015), Lim KH (2015), Reddy BA (2014), Reddy BA (2014)	29
UBC	7	TCEAL1	3	pull down	Zhang X (2017)	1
TRIM27	2	UHRF2	1	two hybrid	Woodsmith J (2012)	1
RB1	2	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Nielsen SJ (2001), Nielsen SJ (2001), Vandel L (2001), Vandel L (2001), Vandel L (2001)	5
SMAD3	1	BRCA1	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dubrovska A (2005), Dubrovska A (2005), Dubrovska A (2005), Li H (2009), Li H (2009)	5
TRIM27	2	BMI1	0	two hybrid	Woodsmith J (2012)	1
TCEAL1	3	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP7	14	TRIP12	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Liu X (2016), Liu X (2016)	3
TP53	0	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen D (2005), Chen D (2005), Chen D (2005), Chen D (2005), Rolfo A (2012), Rolfo A (2012)	6
GLI1	3	TRIM27	2	affinity chromatography technology	Li X (2015)	1
CCDC6	3	APC	5	affinity chromatography technology	Huttlin EL (2017)	1
UBE2E1	1	RNF2	1	two hybrid, affinity chromatography technology, pull down	Markson G (2009), Wheaton K (2017), Wheaton K (2017)	3
USP11	3	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Ke JY (2014), Ke JY (2014)	3
XPC	1	MDM2	2	affinity chromatography technology, pull down	Krzeszinski JY (2013), Krzeszinski JY (2013)	2
RING1	2	CBX8	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bardos JI (2000), Bardos JI (2000), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Rolland T (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	9
MARCH7	0	UBE2E1	1	pull down	Flach K (2014)	1
POLH	1	RAD18	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Yuasa MS (2006), Yuasa MS (2006), Day TA (2010), Watanabe K (2004), Watanabe K (2004), Watanabe K (2004), Lin JR (2011), Durando M (2013)	8
SOX2	4	ANXA1	1	affinity chromatography technology	Huttlin EL (2015)	1
USP7	14	KMT2E	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ding X (2015), Ding X (2015), Ding X (2015)	3
PPP2CA	7	TP53	0	affinity chromatography technology	Shouse GP (2011)	1
SMAD3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Charbonney E (2011), Zhou B (2012)	4
NOTCH1	25	RB1	2	affinity chromatography technology	Yatim A (2012)	1
BCOR	2	PCGF1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gearhart MD (2006), Gearhart MD (2006), Gearhart MD (2006), Gao Z (2012), Junco SE (2013), Junco SE (2013), Hein MY (2015), Oliviero G (2015), Oliviero G (2015), Oliviero G (2015), Oliviero G (2015), Hauri S (2016)	13
PCGF1	1	YAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	5
MDM2	2	EED	1	affinity chromatography technology	Wienken M (2016)	1
NOTCH1	25	USP7	14	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
ZEB1	3	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhang P (2014), Zhang P (2014), Zhang P (2014), Zhou Z (2017), Zhou Z (2017)	5
USP7	14	RNF169	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Hein MY (2015), An L (2017), An L (2017), An L (2017), An L (2017), An L (2017)	6
DNMT1	5	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Zhang J (2011), Lai M (2016)	2
IKBKG	0	KIF23	0	affinity chromatography technology	Simon GC (2008)	1
SMAD3	1	USP7	14	affinity chromatography technology, two hybrid	Brown KA (2008), Wang J (2011)	2
CRY1	0	GMPS	1	affinity chromatography technology	Papp SJ (2015)	1
BRCA1	7	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li H (2010), Li H (2010), Li H (2010), Ertych N (2016)	4
USP7	14	UHRF2	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Hayes SD (2012), Liu Y (2016), Lai M (2016)	3
YAF2	1	MDM2	2	affinity chromatography technology	Huttlin EL (2017)	1
PCGF2	3	USP11	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
MDM2	2	SIRT7	1	affinity chromatography technology	Nihira NT (2017)	1
RNF2	1	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Hein MY (2015), Hauri S (2016), Hauri S (2016)	10
RNF169	1	UBC	7	pull down, pull down	Panier S (2012), Chen J (2012)	2
SIRT7	1	TP53	0	affinity chromatography technology	Tsai YC (2012)	1
CSNK2A1	15	BRCA1	7	pull down	OBrien KA (1999)	1
USP7	14	SVIL	9	pull down, pull down, affinity chromatography technology	Fang Z (2013), Fang Z (2013), Fang Z (2013)	3
PML	7	CTNNB1	30	affinity chromatography technology, pull down, affinity chromatography technology	Satow R (2012), Satow R (2012), Shtutman M (2002)	3
MYC	2	FOXO3	1	affinity chromatography technology	Chandramohan V (2008)	1
PML	7	KAT5	1	affinity chromatography technology, pull down	Wu Q (2009), Wu Q (2009)	2
KMT2E	7	TP53	0	affinity chromatography technology	Cheng F (2011)	1
UHRF1	3	UHRF2	1	affinity chromatography technology	Ma H (2012)	1
FOXO4	0	USP7	14	affinity chromatography technology, affinity chromatography technology	van der Horst A (2006), Szypowska AA (2011)	2
USP11	3	CBX8	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
TP53	0	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Legube G (2004), Tyteca S (2006), Tyteca S (2006), Kurash JK (2008), Cheng Z (2008), Cheng Z (2008), Cheng Z (2008), Tang Y (2006), Tang Y (2006), Tang Y (2006), Dai C (2013)	11
TP53	0	ABRAXAS2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang J (2014), Zhang J (2014), Zhang J (2014), Huttlin EL (2015), Huttlin EL (2017)	5
USP7	14	MCMBP	3	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, pull down	Sowa ME (2009), Jagannathan M (2014), Jagannathan M (2014), Jagannathan M (2014), Jagannathan M (2014)	5
BMI1	0	USP11	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
BCOR	2	RNF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gao Z (2012), Cao Q (2014), Hein MY (2015), Hein MY (2015), Oliviero G (2015), Hauri S (2016)	7
23429	0	TP53	0	affinity chromatography technology	Chen D (2009)	1
NOTCH1	25	RBPJ	1	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nam Y (2003), Aster JC (1997), Aster JC (1997), Gao J (2010), Gao J (2010), Kim MY (2007), Kim MY (2007), Popko-Scibor AE (2011), Mo JS (2007), Kim MY (2011), Kim MY (2011), Yatim A (2012), Yatim A (2012), Choi YH (2013), Jeffries S (2002), Jeffries S (2002), Jeffries S (2002), Kitagawa M (2001), Cho S (2011), Baek HJ (2015), Baek HJ (2015), Huttlin EL (2015), Hein MY (2015), Li X (2015), Huttlin EL (2017), Tremblay CS (2009), Tremblay CS (2009)	27
23429	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Huttlin EL (2015), Huttlin EL (2017)	3
POLH	1	MDM2	2	affinity chromatography technology	Jung YS (2012)	1
PHF8	6	XPC	1	affinity chromatography technology	Hein MY (2015)	1
CSNK2A1	15	TMPO	0	enzymatic study	Zhang M (2011)	1
TMPO	0	PCGF2	3	affinity chromatography technology	Ju WN (2009)	1
USP11	3	TRIP12	20	affinity chromatography technology	Sowa ME (2009)	1
SIRT7	1	TRRAP	31	affinity chromatography technology	Tsai YC (2012)	1
RELA	1	PPARG	0	affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Hou Y (2012), Hou Y (2012), Lu X (2013), Chen F (2003), Chen F (2003), Perez A (2008), Jeninga EH (2007)	7
USP7	14	PPIL4	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hein MY (2015)	2
PHF8	6	OGT	4	affinity chromatography technology	Wang Q (2016)	1
TRRAP	31	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bhattacharya S (2015), Bhattacharya S (2015), Bhattacharya S (2015)	3
USP7	14	RARA	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yang WC (2012), Yang WC (2012), Yang WC (2012)	3
ZBTB44	0	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CSNK2A1	15	USP7	14	enzymatic study, enzymatic study	Carra G (2017), Khoronenkova SV (2012)	2
BRCA1	7	PKM	1	affinity chromatography technology	Ertych N (2016)	1
PHF7	5	TCEAL1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTEN	24	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EED	1	TRIP12	20	affinity chromatography technology	Cao Q (2014)	1
USP7	14	GMPS	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van der Knaap JA (2005), van der Knaap JA (2005), van der Knaap JA (2005), Sowa ME (2009), Sarkari F (2009), Wan C (2015), Hein MY (2015), Pfoh R (2015), Pfoh R (2015), Reddy BA (2014), Reddy BA (2014)	11
USP7	14	TRIM8	6	two hybrid, two hybrid	Hayes SD (2012), Wang J (2011)	2
PCGF1	1	RING1	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Gearhart MD (2006), Gao Z (2012), Gao Z (2012), Woodsmith J (2012), Oliviero G (2015), Oliviero G (2015), Hauri S (2016), Hauri S (2016)	9
USP11	3	WRAP53	1	biochemical	Havugimana PC (2012)	1
UHRF2	1	GMPS	1	affinity chromatography technology	Lai M (2016)	1
IKBKG	0	TRAF6	0	pull down, pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Lamothe B (2008), Windheim M (2008), Lamothe B (2007), Gautheron J (2010), Gautheron J (2010), Hinz M (2010), Sebban-Benin H (2007), Zotti T (2014), Sun L (2004), Emmerich CH (2013), Zhou L (2014), Chen J (2015), Kim EK (2017), Medunjanin S (2016), Xing J (2016), Bal E (2017), Bal E (2017)	17
SOX2	4	ZEB1	3	affinity chromatography technology	Engelen E (2011)	1
MYD88	1	USP7	14	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
RELA	1	PPP2CA	7	pull down	Yang J (2001)	1
MAGEL2	6	USP7	14	affinity chromatography technology, bioid	Hao YH (2013), Wijesuriya TM (2017)	2
PCGF2	3	RING1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Maertens GN (2009), Gao Z (2012), Gao Z (2012), Woodsmith J (2012), Yu H (2011), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
BCOR	2	PCGF2	3	affinity chromatography technology	Oliviero G (2015)	1
USP11	3	RNF2	1	affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010)	2
CHEK1	2	USP11	3	genetic interference	Srivas R (2016)	1
RELA	1	AR	3	genetic interference, genetic interference	Aarnisalo P (1998), Aarnisalo P (1998)	2
USP7	14	ACD	1	two hybrid, affinity chromatography technology	Lim J (2006), Huttlin EL (2017)	2
PPARG	0	KAT5	1	pull down, unspecified method	van Beekum O (2008), Lee G (2002)	2
PML	7	RELA	1	affinity chromatography technology, affinity chromatography technology	Wu WS (2003), Chen Y (2015)	2
HUWE1	22	NCL	1	affinity chromatography technology	Thompson JW (2014)	1
RARA	5	SUV39H1	0	affinity chromatography technology	Carbone R (2006)	1
MYC	2	PHLDB2	5	affinity chromatography technology	Agrawal P (2010)	1
BRCA1	7	MCM4	3	affinity chromatography technology	Ertych N (2016)	1
EED	1	AR	3	affinity chromatography technology	Cao Q (2014)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
BRCA1	7	EED	1	pull down	Wang L (2013)	1
IKBKG	0	ARL6IP4	2	pull down	Fenner BJ (2010)	1
PTEN	24	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Wu Y (2013), Zhang J (2013), Zhang J (2013), Yuan L (2015)	4
BMI1	0	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2009), Maertens GN (2009), Maertens GN (2010), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	11
YAF2	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Huttlin EL (2017)	2
TRIP12	20	UBC	7	affinity chromatography technology	Park Y (2009)	1
PPARG	0	MDM2	2	affinity chromatography technology	Xu Y (2016)	1
USP7	14	MYC	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Tavana O (2016), Tavana O (2016), Tavana O (2016), Tavana O (2016)	4
TCEAL4	0	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
UHRF2	1	EED	1	affinity chromatography technology	Lai M (2016)	1
BCOR	2	RING1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Hein MY (2015), Oliviero G (2015), Hauri S (2016)	4
USP7	14	SCML2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sowa ME (2009), Lecona E (2015), Lecona E (2015), Lecona E (2015), Lecona E (2015), Hein MY (2015)	6
FOXO3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Essers MA (2005), Essers MA (2005)	2
PML	7	RARA	5	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhong S (1999), Zhong S (1999), Minucci S (2000), Kraemer OH (2008), Wang K (2010), Wang K (2010), Cote S (2000), Bellodi C (2006), Villa R (2007)	9
FOXO3	1	BRCA1	7	affinity chromatography technology	Tsai WB (2008)	1
TP53	0	NCL	1	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down	Daniely Y (2002), Daniely Y (2002), Daniely Y (2002), Lim KH (2015)	4
CTNNB1	30	AR	3	pull down, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yang F (2002), Yang F (2002), Masiello D (2004), Song LN (2004), Amir AL (2003), Amir AL (2003), Mulholland DJ (2003), Mulholland DJ (2003), Pawlowski JE (2002), Mulholland DJ (2003), Levy L (2004)	11
MYC	2	GLI1	3	genetic interference	Toyoshima M (2012)	1
RNF2	1	NCL	1	affinity chromatography technology	Cao Q (2014)	1
DNMT1	5	HIST2H2AC	1	affinity chromatography technology	Qin W (2015)	1
BMI1	0	RING1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Satijn DP (1997), Satijn DP (1997), Satijn DP (1999), Satijn DP (1999), Cao R (2005), Cao R (2005), Maertens GN (2009), Wei J (2006), Wang H (2004), Gao Z (2012), Gao Z (2012), Boukarabila H (2009), Abdel-Wahab O (2012), Woodsmith J (2012), Rolland T (2014), Cao Q (2014), Hauri S (2016), Hauri S (2016)	18
AR	3	BCOR	2	bioid	Lempiaeinen JK (2017)	1
FBXO38	3	RING1	2	two hybrid	Wang J (2011)	1
USP7	14	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, biochemical, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lu X (2007), Becker K (2007), Pereg Y (2006), Hu M (2006), Hu M (2006), Hu M (2006), Hu M (2006), Sarkari F (2010), Sarkari F (2010), Tang J (2006), Tang J (2006), Ma J (2010), Song MS (2008), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Ye M (2015), Lim KH (2015), Reddy BA (2014), Rouge L (2016), Nihira NT (2017), Nihira NT (2017), Mungamuri SK (2016), Mungamuri SK (2016), Sun Y (2017)	25
AR	3	TCF20	18	affinity chromatography technology, pull down, bioid	Elvenes J (2011), Elvenes J (2011), Lempiaeinen JK (2017)	3
KAT5	1	RELA	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Kim JW (2012), Kim JW (2012), Kim JW (2012)	3
ARL6IP4	2	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBPJ	1	OGT	4	affinity chromatography technology	Li X (2015)	1
AR	3	PPP2CA	7	affinity chromatography technology	Ni L (2010)	1
ABL1	9	RB1	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Miyamura T (1997), Welch PJ (1993), Knudsen ES (1996), Knudsen ES (1996), Welch PJ (1995), Welch PJ (1995)	6
HUWE1	22	MYC	2	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Adhikary S (2005), Adhikary S (2005), Adhikary S (2005), Koch HB (2007), Fan L (2015), Zhao X (2008)	6
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
UHRF2	1	BMI1	0	affinity chromatography technology	Lai M (2016)	1
WWP2	7	SMAD3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, two hybrid	Soond SM (2011), Soond SM (2011), Soond SM (2011), Brown KA (2008), Soond SM (2013), Yu H (2011)	6
MDM2	2	MYD88	1	two hybrid	Wang J (2011)	1
UBC	7	NCL	1	affinity chromatography technology	Matsumoto M (2005)	1
DAXX	5	AR	3	two hybrid, pull down, affinity chromatography technology, pull down	Lin DY (2004), Lin DY (2004), Lin DY (2004), Sun S (2016)	4
CTNNB1	30	TRRAP	31	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sustmann C (2008), Sierra J (2006), Sierra J (2006), Gomes NP (2006)	4
TFIP11	5	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down	Ye M (2015), Ye M (2015), Ye M (2015)	3
BMI1	0	HIST2H2AC	1	enzymatic study, enzymatic study	Li Z (2006), Bentley ML (2011)	2
PTEN	24	SUV39H1	0	genetic interference	Vizeacoumar FJ (2013)	1
ABL1	9	TP53	0	pull down	Nie Y (2000)	1
WRAP53	1	XPC	1	biochemical	Havugimana PC (2012)	1
PTEN	24	TRIM8	6	genetic interference	Vizeacoumar FJ (2013)	1
MDM4	0	TP53	0	enzymatic study, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, protein complementation assay, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfe, pull down	Badciong JC (2002), Shvarts A (1997), Shvarts A (1997), Tang Y (2008), Okamoto K (2005), Chen L (2005), Wang X (2001), Ohtsubo C (2009), Zdzalik M (2010), Singh RK (2007), Kim S (2010), Li M (2011), Li M (2011), David Y (2011), de Graaf P (2003), Wade M (2012), Wade M (2012), Wade M (2012), Stad R (2000), Stad R (2000), Bernal F (2010), Bernal F (2010), Bernal F (2010), Bernal F (2010), Miller KR (2010), Zuckerman V (2009), Kallen J (2009), Czarna A (2009), Czarna A (2009), Popowicz GM (2008), Hu B (2007), Sharp DA (1999), Li C (2002), Di Conza G (2012), Mancini F (2009), Mancini F (2009), Wu S (2012), Shan B (2012), Wu S (2012), Wu S (2012), Ranaweera RS (2013), Bista M (2013), Bista M (2013), Wang CL (2014), Wang CL (2014), Rallapalli R (1999), Chang YS (2013), Chang YS (2013), Tan BX (2014), Huttlin EL (2015), Sanchez MC (2010), Sanchez MC (2010), Li YC (2014), Li X (2015), Chen X (2015), Chen L (2015), Chen L (2015), Chen L (2015), Wei X (2016), Wei X (2016), Xie X (2016), Huttlin EL (2017), Borcherds W (2017), Shangary S (2008), Ivanov AA (2017), Mancini F (2016)	66
PCGF2	3	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Maertens GN (2009), Maertens GN (2009), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
TRAF6	0	UBE2E1	1	pull down	Markson G (2009)	1
PML	7	ATXN1	2	imaging technique, enzymatic study	Guo L (2014), Guo L (2014)	2
USP7	14	FOXN2	2	affinity chromatography technology, affinity chromatography technology, pull down	Qing P (2011), Qing P (2011), Qing P (2011)	3
RNF2	1	AR	3	affinity chromatography technology	Cao Q (2014)	1
PTEN	24	BMI1	0	affinity chromatography technology, affinity chromatography technology	Fan C (2009), Fan C (2009)	2
OGT	4	FOXO4	0	affinity chromatography technology	Ho SR (2010)	1
PHF8	6	TRIP12	20	affinity chromatography technology	Hein MY (2015)	1
UHRF1	3	RB1	2	affinity chromatography technology, affinity chromatography technology	Jeanblanc M (2005), Jeanblanc M (2005)	2
BRCA1	7	GMPS	1	affinity chromatography technology	Ertych N (2016)	1
SMAD3	1	FOXO4	0	affinity chromatography technology	Seoane J (2004)	1
USP7	14	RNF220	2	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lim J (2006), Ma P (2014), Ma P (2014)	4
USP7	14	ANXA1	1	affinity chromatography technology, affinity chromatography technology, pull down	Park JJ (2015), Park JJ (2015), Park JJ (2015)	3
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
RNF2	1	SCML2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Cao Q (2014), Lecona E (2015), Hein MY (2015)	4
RBPJ	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UHRF1	3	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma H (2012), Ma H (2012), Ma H (2012)	3
PML	7	MDM2	2	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bernardi R (2004), Bernardi R (2004), Zhu H (2003), Zhu H (2003), Kurki S (2003), Kurki S (2003), Wei X (2003), Wei X (2003), Wu Q (2009), Chu Y (2011), Yang Q (2013), Yang Q (2013), Bursac S (2012)	13
CSNK2A1	15	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study	Uhle S (2003), Fogeron ML (2013), Bhansali M (2014), Chen TC (2014), Walerych D (2004), Walerych D (2004)	6
NOTCH1	25	RING1	2	affinity chromatography technology	Yatim A (2012)	1
CHEK1	2	CLSPN	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Chini CC (2003), Chini CC (2003), Chini CC (2006), Chini CC (2006), Chini CC (2006), Huh J (2013), Clarke CA (2005), Clarke CA (2005)	8
BMI1	0	SCML2	1	affinity chromatography technology	Lecona E (2015)	1
HUWE1	22	PKM	1	affinity chromatography technology	Thompson JW (2014)	1
CHFR	5	RELA	1	affinity chromatography technology, affinity chromatography technology	Kashima L (2009), Kashima L (2009)	2
MDM4	0	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uchida C (2006), Uchida C (2006), Zhang H (2015), Zhang H (2015)	4
TRIM27	2	PML	7	affinity chromatography technology	Cao T (1998)	1
ATXN1	2	UBE2E1	1	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hong S (2008), Hong S (2008), Hong S (2008), Hong S (2008), Hong S (2008), Kang AR (2015)	6
WWP2	7	PPM1G	1	affinity chromatography technology, affinity chromatography technology	Chaudhary N (2014), Chaudhary N (2014)	2
TRIM8	6	UHRF2	1	two hybrid	Woodsmith J (2012)	1
ZEB1	3	SMAD3	1	affinity chromatography technology	Postigo AA (2003)	1
PML	7	PKM	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shimada N (2008), Shimada N (2008), Shimada N (2008)	3
BCOR	2	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
MYC	2	TMPO	0	affinity chromatography technology	Koch HB (2007)	1
TP53	0	TCEAL4	0	affinity chromatography technology	Fogeron ML (2013)	1
IKBKG	0	MYC	2	affinity chromatography technology	Kim BY (2010)	1
BRCA1	7	DNMT1	5	affinity chromatography technology	Hill SJ (2014)	1
RB1	2	MDM2	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Hsieh JK (1999), Nguyen DX (2004), Zheng Z (2012), Sdek P (2005), Delston RB (2011), Delston RB (2011), Sdek P (2004), Sdek P (2004), Xiao ZX (1995), Xiao ZX (1995), Xiao ZX (1995), Uchida C (2006), Markham D (2006), Chan HM (2001), Chan HM (2001), Zhang H (2015), Zhang H (2015), Jaenicke RU (1996)	18
MDM2	2	FOXO4	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brenkman AB (2008), Brenkman AB (2008), Brenkman AB (2008), Szypowska AA (2011), Szypowska AA (2011), Oteiza A (2011)	6
UBC	7	RAD18	3	affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, pull down, pull down, pull down, pull down	Matsumoto M (2005), Fenner BJ (2009), Bish RA (2007), Rizzo AA (2014), Rizzo AA (2014), Shereda RD (2010), Shereda RD (2010), Panier S (2012), Ali AM (2012), Thach TT (2015)	10
PHF8	6	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang Q (2016), Wang Q (2016), Wang Q (2016), Wang Q (2016), Wang Q (2016)	5
TRAF6	0	TRAF4	1	affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Takeshita F (2005), Takeshita F (2005), Chen TC (2014)	3
DAXX	5	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muromoto R (2004), Muromoto R (2004), Halder UC (2013), Halder UC (2013), Zhang H (2013), Zhang H (2013)	6
SIRT7	1	GMPS	1	affinity chromatography technology	Tsai YC (2012)	1
UBE2E1	1	CHFR	5	two hybrid	Markson G (2009)	1
USP7	14	TCF20	18	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
KAT5	1	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Frank SR (2003), Frank SR (2003), Liu T (2007), Liu T (2007), Kim J (2010), Kim J (2010)	6
PTEN	24	WWP2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study	Crockett DK (2005), Ahmed SF (2012), Wu Y (2013), Maddika S (2011), Maddika S (2011), Maddika S (2011), Bawa-Khalfe T (2016), Bawa-Khalfe T (2016), Bawa-Khalfe T (2016), Chen Z (2016), Chen Z (2016), Chen Z (2017)	12
DNMT1	5	RB1	2	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Robertson KD (2000), Robertson KD (2000), Robertson KD (2000), Pradhan S (2002), Pradhan S (2002)	5
EED	1	DNMT1	5	affinity chromatography technology, imaging technique, affinity chromatography technology	Vire E (2006), Vire E (2006), OHagan HM (2011)	3
CSNK2A1	15	ARL6IP4	2	enzymatic study	Zhang M (2011)	1
CBX8	3	SCML2	1	affinity chromatography technology	Hein MY (2015)	1
RELA	1	NOTCH1	25	affinity chromatography technology	Guan E (1996)	1
BRCA1	7	USP7	14	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
PTEN	24	PKM	1	pull down	Verrastro I (2015)	1
MYC	2	RELA	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Chapman NR (2002), Covic M (2005), Ivanov AA (2017)	3
BMI1	0	KAT5	1	two hybrid	Stelzl U (2005)	1
RNF2	1	UBC	7	enzymatic study	Woodsmith J (2012)	1
MYC	2	MDM2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SUV39H1	0	CTNNB1	30	affinity chromatography technology	Takahashi A (2011)	1
USP7	14	TBCB	2	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
SOX2	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cox JL (2013), Xu C (2013), Xu C (2013)	3
NOTCH1	25	RNF2	1	affinity chromatography technology	Yatim A (2012)	1
POLH	1	SIRT7	1	affinity chromatography technology	Hein MY (2015)	1
RELA	1	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Colleran A (2013), Colleran A (2013), Colleran A (2013)	3
MDM2	2	FOXO3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fu W (2009), Fu W (2009), Yang JY (2008), Yang JY (2008), Du WW (2017), Du WW (2017), Du WW (2017), Du WW (2017)	8
UHRF2	1	RB1	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Lai M (2016)	5
RARA	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ying M (2016), Ying M (2016), Ying M (2016)	3
IKBKG	0	RELA	1	enzymatic study	Dan HC (2008)	1
EED	1	PCGF2	3	affinity chromatography technology	Cao Q (2014)	1
WWP2	7	PKM	1	affinity chromatography technology	Chaudhary N (2014)	1
AR	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Chen ST (2015), Chen ST (2015), Chen ST (2015), Chen ST (2015)	4
USP7	14	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Mungamuri SK (2016), Mungamuri SK (2016)	2
RB1	2	MYC	2	two hybrid, fluorescent resonance energy transfe	Adnane J (1995), Ivanov AA (2017)	2
CSNK2A1	15	DAXX	5	enzymatic study	Chang CC (2011)	1
ZEB1	3	CHEK1	2	affinity chromatography technology	Zhang P (2014)	1
PCGF1	1	BMI1	0	biochemical	Oliviero G (2015)	1
BRCA1	7	HUWE1	22	affinity chromatography technology, affinity chromatography technology	Wang X (2014), Wang X (2014)	2
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
CHEK1	2	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Palii SS (2008), Palii SS (2008), Ha K (2011)	3
MYC	2	PML	7	affinity chromatography technology, affinity chromatography technology, pull down	Cairo S (2005), Buschbeck M (2007), Buschbeck M (2007)	3
UBC	7	POLH	1	pull down, two hybrid, pull down, two hybrid, pull down, affinity chromatography technology	Bienko M (2005), Plosky BS (2006), Sekimoto T (2010), Bienko M (2005), Plosky BS (2006), Ahmed-Seghir S (2015)	6
PML	7	PPARG	0	two hybrid	Ravasi T (2010)	1
FOXO4	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Essers MA (2005), Szypowska AA (2011)	2
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
MCMBP	3	MCM4	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
KAT5	1	DNMT1	5	affinity chromatography technology	Du Z (2010)	1
TP53	0	XPC	1	affinity chromatography technology	Krzeszinski JY (2013)	1
DAXX	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Ivanchuk SM (2008), Ivanchuk SM (2008), Tang J (2006), Tang J (2006), Tang J (2006), Song MS (2008), Zhao LY (2004), Tang J (2013), Tang J (2013), Zhao LY (2004), Zhang H (2013), Zhang H (2013), Li Z (2017)	13
PJA1	1	EED	1	enzymatic study	Zoabi M (2011)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
RNF2	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Calao M (2012), Wen W (2013), Wen W (2013)	3
USP7	14	RING1	2	affinity chromatography technology, pull down, affinity chromatography technology	Maertens GN (2010), de Bie P (2010), Hein MY (2015)	3
ABL1	9	TMPO	0	enzymatic study	Tifft KE (2009)	1
BMI1	0	YAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Gao Z (2012), Cao Q (2014), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
PPARG	0	USP7	14	affinity chromatography technology, enzymatic study	Lee KW (2013), Lee KW (2013)	2
USP11	3	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
TP53	0	FOXO3	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Du WW (2017), Du WW (2017)	3
USP7	14	PPP2CA	7	affinity chromatography technology, affinity chromatography technology	Park JJ (2015), Park JJ (2015)	2
TRAF4	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Wang A (2014), Wang A (2014)	2
ING1	2	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung KM (2002), Garkavtsev I (1998), Zhu Z (2009)	3
SMAD3	1	PML	7	affinity chromatography technology	Lin HK (2004)	1
AR	3	TP53	0	genetic interference	Shenk JL (2001)	1
ABL1	9	BRCA1	7	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, fluorescent resonance energy transfe	Foray N (2002), Foray N (2002), Foray N (2002), Foray N (2002), Foray N (2002), Morell M (2007)	6
UHRF1	3	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Achour M (2009), Du Z (2010), Dai C (2013), Dai C (2013), Dai C (2013)	5
SUV39H1	0	ABRAXAS2	1	affinity chromatography technology	Huttlin EL (2017)	1
USP7	14	RAD18	3	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Zlatanou A (2016), Zlatanou A (2016), Zlatanou A (2016), Zlatanou A (2016)	4
WWP2	7	MYC	2	affinity chromatography technology, affinity chromatography technology	Yu Z (2016), Yu Z (2016)	2
KAT5	1	TRRAP	31	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyon Y (2006), Chailleux C (2010), Kim J (2010), Kim J (2010), Doyon Y (2004), Doyon Y (2004), Ikura T (2000), Ikura T (2000), Huttlin EL (2015), Jacquet K (2016), Huttlin EL (2017)	11
ZEB1	3	KAT5	1	two hybrid	Hlubek F (2001)	1
RNF169	1	HIST2H2AC	1	affinity chromatography technology	Panier S (2012)	1
TCF20	18	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
FAM170A	0	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP7	14	CHEK1	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Qing P (2011), Zhang P (2014), Zhang P (2014), Tan X (2015), Alonso-de Vega I (2014)	5
USP7	14	GLI1	3	affinity chromatography technology, affinity chromatography technology	Zhou Z (2015), Zhou Z (2015)	2
RBPJ	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Procopio MG (2015), Procopio MG (2015), Procopio MG (2015)	3
YAF2	1	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	4
MYC	2	SMAD3	1	affinity chromatography technology, pull down, two hybrid	Feng XH (2002), Feng XH (2002), Feng XH (2002)	3
UHRF2	1	CTNNB1	30	far western blotting	Mori T (2011)	1
CTNNB1	30	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study, unspecified method	Novellasdemunt L (2017), Novellasdemunt L (2017), Novellasdemunt L (2017), Novellasdemunt L (2017)	4
UBC	7	APC	5	affinity chromatography technology	Matsumoto M (2005)	1
EED	1	23429	0	affinity chromatography technology	Cao Q (2014)	1
MYC	2	PPP2CA	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Arnold HK (2009), Junttila MR (2007), Cianfanelli V (2015), Cianfanelli V (2015)	4
IKBKG	0	MYD88	1	pull down	Emmerich CH (2013)	1
SIRT7	1	PPM1G	1	affinity chromatography technology	Tsai YC (2012)	1
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
RNF168	0	UBE2E1	1	pull down	Poulsen M (2012)	1
UBC	7	CSNK2A1	15	affinity chromatography technology	Matsumoto M (2005)	1
USP7	14	UVSSA	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Schwertman P (2012), Fei J (2012), Fei J (2012), Higa M (2016), Higa M (2016), Higa M (2016)	6
UBC	7	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study	Nathan JA (2013), Bish RA (2007), Thompson JW (2014), Kristariyanto YA (2015), Zhang X (2017), Michel MA (2017)	6
USP7	14	FBXO38	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hein MY (2015)	2
ABL1	9	USP7	14	enzymatic study, affinity chromatography technology, affinity chromatography technology	Morotti A (2013), Morotti A (2013), Morotti A (2013)	3
KAT5	1	NOTCH1	25	affinity chromatography technology, genetic interference, affinity chromatography technology	Kim MY (2007), Kim SY (2007), Kim SY (2007)	3
CLSPN	1	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lin SY (2004), Lin SY (2004), Sato K (2012)	3
UHRF1	3	SUV39H1	0	affinity chromatography technology, affinity chromatography technology	Babbio F (2012), Babbio F (2012)	2
23429	0	CSNK2A1	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	5
EED	1	TMPO	0	affinity chromatography technology	Cao Q (2014)	1
USP7	14	GLI2	4	affinity chromatography technology, affinity chromatography technology	Zhou Z (2015), Zhou Z (2015)	2
USP7	14	TMPO	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Lim J (2006), Hein MY (2015), Brady GF (2018)	3
CSNK2A1	15	NCL	1	enzymatic study, biochemical	Zhang M (2011), Wan C (2015)	2
SMAD3	1	PJA1	1	affinity chromatography technology	Brown KA (2008)	1
KMT2E	7	OGT	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ding X (2015), Ding X (2015), Ding X (2015)	3
EED	1	TRRAP	31	affinity chromatography technology	Cao Q (2014)	1
UBC	7	FOXN2	2	affinity chromatography technology	Bish RA (2007)	1
BRCA1	7	OGT	4	affinity chromatography technology	Ertych N (2016)	1
UBC	7	IKBKG	0	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Dynek JN (2010), Dynek JN (2010), Chiaravalli J (2011), Laplantine E (2009), Hubeau M (2011), Lo YC (2009), Ikeda F (2010), Cordier F (2009), Cordier F (2009), Cordier F (2009), Renner F (2011), Fenner BJ (2009), Fenner BJ (2009), Ivins FJ (2009), Rahighi S (2009), Rahighi S (2009), Zhu G (2007), Zhu G (2007), Niu J (2011), Keusekotten K (2013), van Wijk SJ (2013), Hooper C (2014), Wagner S (2008), Saul VV (2014), Gleason CE (2011), Komander D (2009), Kensche T (2012), Skaug B (2011), Ea CK (2006), Ea CK (2006), Lo YC (2009), Laplantine E (2009), Laplantine E (2009), Emmerich CH (2013), Dubosclard V (2015), Vincendeau M (2015), Vincendeau M (2016), Zhang X (2017), Fang R (2017), Kliza K (2017), Joo D (2016), Fang R (2017), Hauenstein AV (2017)	43
BRCA1	7	RNF169	1	affinity chromatography technology	Hill SJ (2014)	1
RNF2	1	UHRF1	3	affinity chromatography technology	Cao Q (2014)	1
MYD88	1	SMAD3	1	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
TP53	0	RAE1	0	affinity chromatography technology	Fogeron ML (2013)	1
ABL1	9	MDM4	0	affinity chromatography technology, affinity chromatography technology	Zuckerman V (2009), Zuckerman V (2009)	2
CSNK2A1	15	PTEN	24	enzymatic study, pull down, affinity chromatography technology, enzymatic study	Miller SJ (2002), Miller SJ (2002), Crockett DK (2005), Li Z (2014)	4
NOTCH1	25	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down	Jin YH (2009), Jin YH (2009), Jin YH (2009)	3
CSNK2A1	15	MYC	2	enzymatic study	Channavajhala P (2002)	1
HUWE1	22	MDM2	2	affinity chromatography technology, enzymatic study	Kurokawa M (2013), Kurokawa M (2013)	2
EED	1	BCOR	2	affinity chromatography technology	Cao Q (2014)	1
UHRF2	1	KAT5	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2017), Zeng S (2017)	2
MDM4	0	SMAD3	1	pull down	Kadakia M (2002)	1
KAT5	1	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Du Z (2010), Dar A (2013), Dar A (2013), Dar A (2013), Cui H (2015)	5
FAM170A	0	TRIM27	2	affinity chromatography technology	Huttlin EL (2015)	1
CRY1	0	MCM4	3	affinity chromatography technology	Papp SJ (2015)	1
HUWE1	22	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Thompson JW (2014), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017)	4
CHEK1	2	MDM4	0	enzymatic study, enzymatic study	Jin Y (2006), Chen L (2005)	2
APC	5	MBD4	1	affinity chromatography technology	Hein MY (2015)	1
USP7	14	MCM4	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lecona E (2016)	2
AR	3	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016)	18
CRY1	0	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Papp SJ (2015), Papp SJ (2015), Papp SJ (2015)	3
PHF7	5	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EED	1	RING1	2	affinity chromatography technology, imaging technique, affinity chromatography technology	Cao Q (2014), Cao Q (2014), Cao Q (2014)	3
PPARG	0	UBC	7	enzymatic study	Hou Y (2012)	1
BRCA1	7	HIST2H2AC	1	enzymatic study, enzymatic study	Chen A (2002), Thakar A (2010)	2
IKBKG	0	USP7	14	affinity chromatography technology, affinity chromatography technology	Daubeuf S (2009), Li T (2014)	2
USP7	14	TRIM27	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hayes SD (2012), Hein MY (2015), Zaman MM (2013), Zaman MM (2013)	4
USP7	14	PLEKHO1	1	two hybrid, affinity chromatography technology	Lim J (2006), Huttlin EL (2017)	2
USP7	14	XPC	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	He J (2014), He J (2014), He J (2014), He J (2014)	4
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
HUWE1	22	MCM4	3	affinity chromatography technology	Thompson JW (2014)	1
PTEN	24	AR	3	pull down, affinity chromatography technology	Lin HK (2004), Lin HK (2004)	2
NOTCH1	25	USP11	3	affinity chromatography technology	Yatim A (2012)	1
USP7	14	EED	1	pull down, affinity chromatography technology	de Bie P (2010), Cao Q (2014)	2
TRAF6	0	PLEKHO1	1	affinity chromatography technology, pull down	Zhang L (2014), Zhang L (2014)	2
USP7	14	BCOR	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lim J (2006), Hein MY (2015), Hein MY (2015), Oliviero G (2015)	4
NCL	1	DAXX	5	biochemical	Wan C (2015)	1
TRIM27	2	MAGEL2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Doyle JM (2010), Hao YH (2013), Hao YH (2013), Hao YH (2013), Wijesuriya TM (2017)	5
SIRT7	1	NCL	1	affinity chromatography technology	Tsai YC (2012)	1
BRCA1	7	PPP2CA	7	affinity chromatography technology	Woods NT (2012)	1
SMAD3	1	FOXO3	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Seoane J (2004), Fu G (2011), Bollinger LM (2014)	3
CBX8	3	CSNK2A1	15	affinity chromatography technology	Vandamme J (2011)	1
MBD4	1	UHRF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Meng H (2014), Meng H (2014), Meng H (2014), Meng H (2014), Meng H (2014)	5
FOXO3	1	RB1	2	affinity chromatography technology	Li X (2015)	1
USP7	14	CHFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Oh YM (2007), Oh YM (2009), Oh YM (2009)	3
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
UHRF1	3	PML	7	affinity chromatography technology, affinity chromatography technology	Guan D (2012), Guan D (2012)	2
PCGF2	3	RNF2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Elderkin S (2007), Maertens GN (2009), Gao Z (2012), Gao Z (2012), Gao Z (2012), Endoh M (2012), Woodsmith J (2012), Woodsmith J (2012), Cao Q (2014), Taherbhoy AM (2015), Taherbhoy AM (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	15
USP11	3	RING1	2	affinity chromatography technology	Maertens GN (2010)	1
KAT5	1	BRCA1	7	two hybrid	Hill SJ (2014)	1
CTNNB1	30	RNF220	2	affinity chromatography technology, affinity chromatography technology	Ma P (2014), Ma P (2014)	2
RAD18	3	TRIM8	6	two hybrid	Woodsmith J (2012)	1
PTEN	24	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Li A (2010), Li A (2010)	2
MBD4	1	SUV39H1	0	two hybrid	Weimann M (2013)	1
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
MDM2	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Lim SO (2011), Lim SO (2011), Pettersson S (2012), Pettersson S (2012), Pettersson S (2012)	5
RNF168	0	HIST2H2AC	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Stewart GS (2009), Stewart GS (2009), Pinato S (2011), Poulsen M (2012), Mattiroli F (2012)	5
CRY1	0	HUWE1	22	affinity chromatography technology	Papp SJ (2015)	1
USP7	14	PML	7	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Sivachandran N (2010), Sarkari F (2011), Sarkari F (2011), Hein MY (2015)	4
PCGF2	3	BMI1	0	affinity chromatography technology	Huttlin EL (2017)	1
CBX8	3	BCOR	2	affinity chromatography technology	Hauri S (2016)	1
CBX8	3	PCGF1	1	affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Vandamme J (2011), Vandamme J (2011), Oliviero G (2015), Hauri S (2016), Hauri S (2016)	5
CHEK1	2	CSNK2A1	15	pull down, affinity chromatography technology	Kristensen LP (2004), Guerra B (2003)	2
ABL1	9	MDM2	2	affinity chromatography technology, pull down, enzymatic study, unspecified method, enzymatic study	Goldberg Z (2002), Goldberg Z (2002), Goldberg Z (2002), Batuello CN (2015), Batuello CN (2015)	5
TRIM27	2	UBE2E1	1	two hybrid, two hybrid	Napolitano LM (2011), Napolitano LM (2011)	2
SIRT7	1	TCF20	18	affinity chromatography technology	Tsai YC (2012)	1
SIRT7	1	USP11	3	affinity chromatography technology	Tsai YC (2012)	1
RNF168	0	UBC	7	pull down, pull down, pull down, pull down, pull down	Panier S (2012), Feng L (2012), Thorslund T (2015), Luijsterburg MS (2017), Luijsterburg MS (2017)	5
SUV39H1	0	MCMBP	3	affinity chromatography technology	Huttlin EL (2017)	1
PML	7	CSNK2A1	15	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Rabellino A (2012), Stehmeier P (2009), Hung MS (2010), Hung MS (2010), Scaglioni PP (2006)	5
TCEAL4	0	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Hein MY (2015), Hein MY (2015)	5
HIST2H2AC	1	NCL	1	pull down	Angelov D (2006)	1
USP7	14	UBE2E1	1	unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Sarkari F (2013), Wheaton K (2017)	6
ING1	2	TRRAP	31	affinity chromatography technology	Vieyra D (2002)	1
MYC	2	SUV39H1	0	genetic interference, affinity chromatography technology	Toyoshima M (2012), Hauri S (2016)	2
NCL	1	MDM2	2	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Saxena A (2006), Bhatt P (2011), Bhatt P (2011), Miyamoto-Sato E (2010), Okoro DR (2013), Saxena A (2006), Saxena A (2006)	7