Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
TRPM8 79054 ANANDAMIDE CHEMBL15848 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 CLOTRIMAZOLE CHEMBL104 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 D-3263 CHEMBL3707315 agonist TdgClinicalTrial, ChemblInteractions
TRPM8 79054 CHEMBL1289953 CHEMBL1289953 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 LINOLEIC ACID CHEMBL267476 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 5-BENZYLOXYTRYPTAMINE CHEMBL1288652 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 CANNABIDIOL CHEMBL190461 channel blocker GuideToPharmacologyInteractions
TRPM8 79054 MENTHOL CHEMBL256087 inducer TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 14757700, 15311065, 7529306, 15190109, 11752352, 15046718, 12654248

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
TRPM8 rs10166942 C botulinum toxin type a efficacy no No significant difference in allele frequency between responders and non-responders. Allele C is not associated with response to botulinum toxin type a in women with Migraine NOS as compared to allele T. 31014225 1451105019