PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
BAALC	0	CHD1L	5	two hybrid	Morita K (2015)	1
BAALC	0	OSBPL1A	1	two hybrid	Morita K (2015)	1
BAALC	0	AP1G1	8	two hybrid	Morita K (2015)	1
BAALC	0	ATP1B3	0	two hybrid	Morita K (2015)	1
BAALC	0	CINP	0	two hybrid	Morita K (2015)	1
MDFI	1	BAALC	0	two hybrid	Rual JF (2005)	1
CHEK2	2	BAALC	0	two hybrid	Arroyo R (2015)	1
ATXN1	2	BAALC	0	two hybrid	Suter B (2013)	1
BAALC	0	RNF2	1	two hybrid	Morita K (2015)	1
BAALC	0	KLF4	2	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Morita K (2015), Morita K (2015), Morita K (2015), Morita K (2015), Morita K (2015)	5
BAALC	0	MAP3K1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Morita K (2015), Morita K (2015), Morita K (2015), Morita K (2015)	4