PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NUP214	3	VPS4B	3	biochemical	Havugimana PC (2012)	1
CDH1	4	EEF1A1	0	bioid	Guo Z (2014)	1
NUP214	3	NUP88	1	affinity chromatography technology, biochemical, affinity chromatography technology	Saito S (2004), Wan C (2015), Huttlin EL (2017)	3
APC	5	XPO1	8	affinity chromatography technology, pull down	Tickenbrock L (2002), Tickenbrock L (2002)	2
NUP35	0	NUP88	1	bioid	Kim DI (2014)	1
CUL7	4	NUP35	0	affinity chromatography technology	Hanson D (2014)	1
FXR2	2	BRCA1	7	two hybrid	Hill SJ (2014)	1
KPNB1	3	11097	0	affinity chromatography technology	Hein MY (2015)	1
SIRT7	1	G3BP1	4	affinity chromatography technology	Tsai YC (2012)	1
RAE1	0	11097	0	affinity chromatography technology	Sowa ME (2009)	1
KPNB1	3	NUP35	0	affinity chromatography technology	Hein MY (2015)	1
HDAC5	4	TRIM28	1	affinity chromatography technology	Greco TM (2011)	1
FBXO6	0	NUP85	6	affinity chromatography technology	Liu B (2012)	1
ITGA4	4	TRIM28	1	affinity chromatography technology	Byron A (2012)	1
FBXO6	0	LMNA	2	affinity chromatography technology	Liu B (2012)	1
KPNB1	3	NUP153	1	pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakielny S (1999), Nakielny S (1999), Kehlenbach RH (2000), Ben-Efraim I (2001), Walther TC (2003), Ciciarello M (2010), Hein MY (2015), Hein MY (2015)	8
SIRT7	1	RANBP2	9	affinity chromatography technology	Tsai YC (2012)	1
IPO5	0	NUP214	3	pull down	Yaseen NR (1997)	1
CUL2	3	RPL19	1	affinity chromatography technology	Bennett EJ (2010)	1
SIRT7	1	NUP214	3	affinity chromatography technology	Tsai YC (2012)	1
SIRT7	1	KPNB1	3	affinity chromatography technology	Tsai YC (2012)	1
NUP85	6	RANBP2	9	bioid	Kim DI (2014)	1
CUL3	17	KPNB1	3	affinity chromatography technology	Bennett EJ (2010)	1
IFI16	1	NUP35	0	affinity chromatography technology	Diner BA (2015)	1
APC	5	NUP214	3	two hybrid	Bandyopadhyay S (2010)	1
KPNB1	3	RAE1	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Blower MD (2005), Blower MD (2005), Blower MD (2005), Wan C (2015), Hein MY (2015)	5
EEF1A1	0	NUP214	3	biochemical	Havugimana PC (2012)	1
NUP214	3	NUP107	1	affinity chromatography technology, bioid, affinity chromatography technology	Bastos R (1997), Kim DI (2014), Hein MY (2015)	3
OBSL1	9	TRIM28	1	affinity chromatography technology	Hanson D (2014)	1
G3BP2	4	NUP153	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SOX2	4	IPO5	0	affinity chromatography technology	Cox JL (2013)	1
BRCA1	7	UBE2I	0	fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, affinity chromatography technology	Morris JR (2009), Morris JR (2009), Xu J (2009), Xu J (2009)	4
NUP85	6	NUP153	1	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
NUP85	6	NUP62	1	bioid	Kim DI (2014)	1
NUP214	3	ZFP36	2	affinity chromatography technology, pull down, two hybrid	Carman JA (2004), Carman JA (2004), Carman JA (2004)	3
SOX2	4	CUL7	4	affinity chromatography technology	Cox JL (2013)	1
OBSL1	9	NUP214	3	affinity chromatography technology	Hanson D (2014)	1
BRCA1	7	KPNB1	3	affinity chromatography technology	Ertych N (2016)	1
SIRT7	1	IPO5	0	affinity chromatography technology	Tsai YC (2012)	1
NUP214	3	CFL1	0	biochemical	Wan C (2015)	1
KPNB1	3	NUP88	1	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	NUP88	1	affinity chromatography technology	Bennett EJ (2010)	1
NUP107	1	APC	5	bioid	Kim DI (2014)	1
NTRK1	1	G3BP1	4	affinity chromatography technology	Emdal KB (2015)	1
NUP107	1	NUP62	1	affinity chromatography technology	Hein MY (2015)	1
NUP153	1	XPO1	8	pull down	Nakielny S (1999)	1
SEH1L	1	NUP35	0	affinity chromatography technology	Hein MY (2015)	1
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
CUL7	4	NUP107	1	affinity chromatography technology	Hanson D (2014)	1
RAN	1	NXF1	0	pull down, pull down	Shamsher MK (2002), Katahira J (1999)	2
ITGA4	4	EEF1A1	0	affinity chromatography technology	Byron A (2012)	1
IFI16	1	RAE1	0	affinity chromatography technology	Diner BA (2015)	1
IPO5	0	RAN	1	pull down, affinity chromatography technology, biochemical	Yaseen NR (1997), Lipowsky G (2000), Wan C (2015)	3
BRCA1	7	NUP214	3	affinity chromatography technology	Ertych N (2016)	1
HDAC9	7	NUP214	3	affinity chromatography technology	Gregoire S (2006)	1
G3BP2	4	NUP214	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017)	3
NUP107	1	NUP35	0	affinity chromatography technology	Hein MY (2015)	1
KPNB1	3	SMAD3	1	pull down, affinity chromatography technology	Xiao Z (2000), Xiao Z (2000)	2
RAE1	0	NUP88	1	affinity chromatography technology	Sowa ME (2009)	1
NUP214	3	PNPT1	1	biochemical	Havugimana PC (2012)	1
FXR2	2	G3BP2	4	affinity chromatography technology	Li S (2014)	1
ITGA4	4	CFL1	0	affinity chromatography technology	Byron A (2012)	1
RAN	1	XPO5	2	two hybrid, pull down, affinity chromatography technology, pull down	Brownawell AM (2002), Brownawell AM (2002), Brownawell AM (2002), Melo SA (2010)	4
CUL7	4	EEF1A1	0	affinity chromatography technology	Hanson D (2014)	1
SOX2	4	XPO5	2	affinity chromatography technology	Cox JL (2013)	1
SIRT7	1	RPL19	1	affinity chromatography technology	Tsai YC (2012)	1
HSPA1L	2	NUP214	3	biochemical	Havugimana PC (2012)	1
IFI16	1	NUP88	1	affinity chromatography technology	Diner BA (2015)	1
KPNB1	3	NUP214	3	affinity chromatography technology	Hein MY (2015)	1
NUP214	3	SMAD4	9	affinity chromatography technology, pull down	Xu L (2003), Xu L (2003)	2
RAN	1	XPO1	8	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical	Tickenbrock L (2002), Fornerod M (1997), Plafker K (2000), Chase GP (2011), Lipowsky G (2000), Havugimana PC (2012), von Knethen A (2010), Wan C (2015)	8
NUP214	3	SMAD3	1	affinity chromatography technology, pull down	Xu L (2003), Xu L (2003)	2
NUP35	0	NUP62	1	bioid	Kim DI (2014)	1
SMAD3	1	HDAC4	10	affinity chromatography technology, pull down	Kang JS (2005), Kang JS (2005)	2
IFI16	1	NUP214	3	affinity chromatography technology	Diner BA (2015)	1
ITGA4	4	IPO5	0	affinity chromatography technology	Byron A (2012)	1
BRCA1	7	LMNA	2	affinity chromatography technology	Ertych N (2016)	1
NUP153	1	PNPT1	1	biochemical	Havugimana PC (2012)	1
IFI16	1	NUP153	1	affinity chromatography technology	Diner BA (2015)	1
OBSL1	9	NXF1	0	affinity chromatography technology	Hanson D (2014)	1
G3BP2	4	NUP62	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015)	2
IFI16	1	NXF1	0	affinity chromatography technology	Diner BA (2015)	1
NUP107	1	NUP85	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loiodice I (2004), Kaur S (2010), Glavy JS (2007), Wan C (2015), Kim DI (2014), Kim DI (2014), Kim DI (2014), Hein MY (2015)	8
LMNA	2	TRIM28	1	bioid, affinity chromatography technology	Roux KJ (2012), Depreux FF (2015)	2
NUP153	1	RAE1	0	affinity chromatography technology	Hein MY (2015)	1
NXF2	0	NUP62	1	pull down	Herold A (2000)	1
HDAC5	4	NUP214	3	affinity chromatography technology	Gregoire S (2006)	1
OBSL1	9	RPL19	1	affinity chromatography technology	Hanson D (2014)	1
SIRT7	1	NUP88	1	affinity chromatography technology	Tsai YC (2012)	1
G3BP1	4	NUP62	1	affinity chromatography technology	Sowa ME (2009)	1
RANBP2	9	HDAC4	10	enzymatic study	Kirsh O (2002)	1
BRCA1	7	XPO1	8	affinity chromatography technology	Ertych N (2016)	1
OBSL1	9	NUP107	1	affinity chromatography technology	Hanson D (2014)	1
CDH1	4	NUP214	3	bioid	Guo Z (2014)	1
SOX2	4	KCMF1	0	affinity chromatography technology	Cox JL (2013)	1
XPO1	8	NUP214	3	affinity chromatography technology, affinity chromatography technology	Lindsay ME (2001), Saito S (2004)	2
NTRK1	1	G3BP2	4	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	G3BP1	4	affinity chromatography technology	Byron A (2012)	1
SMAD2	5	KPNB1	3	two hybrid	Colland F (2004)	1
HDAC5	4	CUL7	4	affinity chromatography technology	Nie J (2015)	1
RAN	1	NUP62	1	affinity chromatography technology	Huttlin EL (2017)	1
EMILIN1	1	NUP214	3	affinity chromatography technology	Huttlin EL (2017)	1
NUP62	1	NUP153	1	pull down, affinity chromatography technology	Stochaj U (2006), Stochaj U (2006)	2
NUP214	3	CSRP1	0	biochemical	Wan C (2015)	1
OBSL1	9	XPO1	8	affinity chromatography technology	Hanson D (2014)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
SEH1L	1	RANBP2	9	affinity chromatography technology	Hein MY (2015)	1
OBSL1	9	EEF1A1	0	affinity chromatography technology	Hanson D (2014)	1
RAE1	0	NUP62	1	affinity chromatography technology	Sowa ME (2009)	1
HDAC4	10	NUP214	3	affinity chromatography technology	Gregoire S (2006)	1
G3BP1	4	LMNA	2	affinity chromatography technology	Jain S (2016)	1
CDH1	4	RAN	1	bioid	Guo Z (2014)	1
NUP107	1	RAE1	0	affinity chromatography technology	Hein MY (2015)	1
NUP153	1	NUP214	3	affinity chromatography technology	Hein MY (2015)	1
RANBP2	9	IPO5	0	biochemical	Wan C (2015)	1
NTRK1	1	NUP88	1	affinity chromatography technology	Emdal KB (2015)	1
CUL7	4	NUP214	3	affinity chromatography technology	Hanson D (2014)	1
NUP153	1	11097	0	affinity chromatography technology	Hein MY (2015)	1
SIRT7	1	FXR2	2	affinity chromatography technology	Tsai YC (2012)	1
LMNA	2	NUP214	3	bioid	Roux KJ (2012)	1
OBSL1	9	NUP153	1	affinity chromatography technology	Hanson D (2014)	1
FBXO6	0	IPO5	0	affinity chromatography technology	Liu B (2012)	1
NUP107	1	NUP58	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
SOX2	4	RAE1	0	affinity chromatography technology	Cox JL (2013)	1
NDUFA7	0	UBE2I	0	biochemical	Havugimana PC (2012)	1
CUL3	17	NUP153	1	affinity chromatography technology	Bennett EJ (2010)	1
IFI16	1	NUP107	1	affinity chromatography technology	Diner BA (2015)	1
ITGA4	4	NUP214	3	affinity chromatography technology	Byron A (2012)	1
NUP58	0	11097	0	affinity chromatography technology	Hein MY (2015)	1
G3BP1	4	CFL1	0	affinity chromatography technology	Jain S (2016)	1
UBE2I	0	XPO1	8	biochemical	Havugimana PC (2012)	1
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
CUL2	3	KPNB1	3	biochemical	Kristensen AR (2012)	1
CUL7	4	CFL1	0	affinity chromatography technology	Hanson D (2014)	1
ITGA4	4	XPO1	8	affinity chromatography technology	Byron A (2012)	1
CUL3	17	NUP107	1	affinity chromatography technology	Bennett EJ (2010)	1
NXF1	0	XPO1	8	affinity chromatography technology	Bachi A (2000)	1
SMAD4	9	UBE2I	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Chang CC (2005), Lin X (2003), Colland F (2004), Wang J (2011), Wang J (2011)	6
NXF1	0	XPO5	2	affinity chromatography technology	Castello A (2012)	1
XPO1	8	SMAD1	0	affinity chromatography technology	Kirli K (2015)	1
SMAD3	1	NUP153	1	pull down	Xu L (2003)	1
CUL3	17	TRIM28	1	affinity chromatography technology	Bennett EJ (2010)	1
NUP107	1	PNPT1	1	biochemical	Havugimana PC (2012)	1
NXF1	0	RAE1	0	affinity chromatography technology, affinity chromatography technology	Bachi A (2000), Bachi A (2000)	2
NUP214	3	NXF1	0	pull down, pull down, two hybrid, pull down, pull down, affinity chromatography technology	Herold A (2000), Schmitt I (2001), Katahira J (1999), Katahira J (1999), Herold A (2000), Huttlin EL (2017)	6
APC	5	NUP153	1	two hybrid	Bandyopadhyay S (2010)	1
RANBP2	9	KPNB1	3	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yaseen NR (1999), Delphin C (1997), Ben-Efraim I (2001), Walther TC (2003), Chi NC (1996), Chi NC (1996), Hein MY (2015)	7
SMAD3	1	BRCA1	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dubrovska A (2005), Dubrovska A (2005), Dubrovska A (2005), Li H (2009), Li H (2009)	5
SIRT7	1	CUL7	4	affinity chromatography technology	Tsai YC (2012)	1
NUP214	3	SMAD2	5	affinity chromatography technology, pull down	Xu L (2003), Xu L (2003)	2
CUL3	17	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
HSPA1L	2	XPO1	8	biochemical	Kristensen AR (2012)	1
NXF1	0	NXF2	0	pull down	Matzat LH (2008)	1
CUL7	4	RAE1	0	affinity chromatography technology	Hanson D (2014)	1
NTRK1	1	CUL3	17	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	NUP107	1	affinity chromatography technology	Emdal KB (2015)	1
HDAC5	4	RAN	1	affinity chromatography technology	Greco TM (2011)	1
NXF1	0	NUP88	1	affinity chromatography technology	Bachi A (2000)	1
CUL3	17	G3BP1	4	affinity chromatography technology	Bennett EJ (2010)	1
G3BP2	4	NUP88	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DDX19A	0	NUP62	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO5	2	NUP214	3	affinity chromatography technology	Brownawell AM (2002)	1
CUL7	4	KPNB1	3	affinity chromatography technology	Hanson D (2014)	1
CLEC4G	0	NUP214	3	two hybrid	Wang J (2008)	1
NTRK1	1	KPNB1	3	affinity chromatography technology	Emdal KB (2015)	1
ITGA4	4	RAN	1	affinity chromatography technology	Byron A (2012)	1
SMAD1	0	SMAD4	9	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Hanai J (1999), Lopez-Rovira T (2002), Kato Y (2002), Wang L (2011), Li L (2004), Hata A (1998), Barrios-Rodiles M (2005), Wu RY (1997), Wu RY (1997), Colland F (2004), Qiu T (2007), Yan X (2016), Zhou F (2017)	14
XPO5	2	EEF1A1	0	pull down	Calado A (2002)	1
UBE2I	0	SEH1L	1	affinity chromatography technology	Hein MY (2015)	1
RANBP2	9	NUP214	3	affinity chromatography technology	Yokoyama N (1995)	1
SOX2	4	NUP214	3	affinity chromatography technology	Cox JL (2013)	1
NUP35	0	NUP58	0	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
UBE2I	0	NUP35	0	affinity chromatography technology	Hein MY (2015)	1
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
NXF1	0	KPNB1	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Zhang ZC (2011), Zhang ZC (2011), Bachi A (2000), Hein MY (2015)	4
RAE1	0	SEH1L	1	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	EEF1A1	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	RAN	1	affinity chromatography technology	Emdal KB (2015)	1
BRCA1	7	CUL2	3	affinity chromatography technology	Ertych N (2016)	1
NUP58	0	NUP62	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Yu H (2011), Hein MY (2015), Huttlin EL (2017)	4
NXF1	0	EEF1A1	0	affinity chromatography technology	Castello A (2012)	1
RAE1	0	NUP214	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015)	2
SIRT7	1	NXF1	0	affinity chromatography technology	Tsai YC (2012)	1
EMSY	3	NUP214	3	affinity chromatography technology	Varier RA (2016)	1
OBSL1	9	RAN	1	affinity chromatography technology	Hanson D (2014)	1
NXF2	0	11097	0	affinity chromatography technology	Huttlin EL (2017)	1
CDH1	4	TXNDC9	0	bioid	Guo Z (2014)	1
CUL3	17	G3BP2	4	affinity chromatography technology	Bennett EJ (2010)	1
NUP214	3	S100A6	1	biochemical	Havugimana PC (2012)	1
SMAD3	1	HDAC5	4	affinity chromatography technology, pull down	Kang JS (2005), Kang JS (2005)	2
CUL7	4	TRIM28	1	affinity chromatography technology	Hanson D (2014)	1
NUP107	1	RAN	1	affinity chromatography technology	Hein MY (2015)	1
G3BP1	4	KPNB1	3	affinity chromatography technology	Jain S (2016)	1
IPO5	0	XPO1	8	biochemical	Wan C (2015)	1
APC	5	NUP58	0	two hybrid	Bandyopadhyay S (2010)	1
NUP153	1	UBE2I	0	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	LMNA	2	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	NUP85	6	affinity chromatography technology	Emdal KB (2015)	1
LMNA	2	RANBP2	9	bioid	Roux KJ (2012)	1
BRCA1	7	NUP107	1	affinity chromatography technology	Ertych N (2016)	1
NTRK1	1	RPL19	1	affinity chromatography technology	Emdal KB (2015)	1
NUP214	3	RPL19	1	biochemical	Havugimana PC (2012)	1
BRCA1	7	TRIM28	1	affinity chromatography technology	Ertych N (2016)	1
NTRK1	1	DDX19A	0	affinity chromatography technology	Emdal KB (2015)	1
BRCA1	7	CDH1	4	genetic interference	Shen JP (2017)	1
SEH1L	1	NUP153	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CUL3	17	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
HDAC4	10	CUL7	4	affinity chromatography technology	Nie J (2015)	1
NUP35	0	NUP214	3	bioid	Kim DI (2014)	1
SIRT7	1	XPO1	8	affinity chromatography technology	Tsai YC (2012)	1
NUP214	3	DYNC1LI1	1	biochemical	Wan C (2015)	1
CUL2	3	RANBP2	9	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	PNPT1	1	affinity chromatography technology	Emdal KB (2015)	1
RAN	1	NUP214	3	affinity chromatography technology	Huttlin EL (2017)	1
SIRT7	1	PNPT1	1	affinity chromatography technology	Tsai YC (2012)	1
NUP58	0	RANBP2	9	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	EMSY	3	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	TRIM28	1	affinity chromatography technology	Emdal KB (2015)	1
SEH1L	1	NUP88	1	affinity chromatography technology	Hein MY (2015)	1
NUP85	6	KPNB1	3	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
HDAC5	4	KPNB1	3	affinity chromatography technology	Greco TM (2011)	1
SIRT7	1	LMNA	2	affinity chromatography technology	Tsai YC (2012)	1
NUP107	1	UBE2I	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CUL3	17	RPL19	1	affinity chromatography technology	Bennett EJ (2010)	1
ITGA4	4	XPO5	2	affinity chromatography technology	Byron A (2012)	1
CFL1	0	CSRP1	0	biochemical	Wan C (2015)	1
FBXO6	0	NUP214	3	affinity chromatography technology	Liu B (2012)	1
CUL2	3	TRIM28	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	DYNC1LI1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	VPS4B	3	affinity chromatography technology	Bennett EJ (2010)	1
KPNB1	3	NUP62	1	pull down, pull down, affinity chromatography technology	Ben-Efraim I (2001), Percipalle P (1997), Walther TC (2003)	3
SMAD1	0	NUP214	3	affinity chromatography technology	Sapkota G (2007)	1
NTRK1	1	NUP214	3	affinity chromatography technology	Emdal KB (2015)	1
NUP214	3	11097	0	two hybrid	Katahira J (1999)	1
NUP62	1	NUP214	3	pull down, biochemical	Stochaj U (2006), Wan C (2015)	2
XPO1	8	ZFP36	2	affinity chromatography technology	Kirli K (2015)	1
NXF2	0	NUP153	1	pull down, affinity chromatography technology	Herold A (2000), Huttlin EL (2017)	2
UBE2I	0	RAN	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
SMAD4	9	XPO5	2	two hybrid	Colland F (2004)	1
NXF1	0	RANBP2	9	affinity chromatography technology, pull down, biochemical	Bachi A (2000), Levesque L (2006), Wan C (2015)	3
NUP153	1	RAN	1	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Nakielny S (1999), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	4
NUP214	3	TRIM28	1	biochemical	Wan C (2015)	1
IPO5	0	NUP153	1	pull down	Yaseen NR (1997)	1
XPO5	2	NUP153	1	affinity chromatography technology	Brownawell AM (2002)	1
UBE2I	0	HDAC4	10	enzymatic study, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Knipscheer P (2008), Zhao X (2005), Zhao X (2005), Dehennaut V (2013), Tatham MH (2001), Knipscheer P (2007)	6
HDAC5	4	HDAC4	10	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Backs J (2008), Backs J (2008), Rui J (2012), Rui J (2012)	4
UBE2I	0	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
DDX19A	0	NXF1	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Castello A (2012)	2
DDX19A	0	XPO1	8	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Kirli K (2015)	3
NUP107	1	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
NDUFA7	0	NUP214	3	biochemical	Havugimana PC (2012)	1
OBSL1	9	RAE1	0	affinity chromatography technology	Hanson D (2014)	1
NXF1	0	CUL2	3	affinity chromatography technology	Castello A (2012)	1
ITGA4	4	KPNB1	3	affinity chromatography technology	Byron A (2012)	1
IFI16	1	FXR2	2	affinity chromatography technology	Diner BA (2015)	1
NUP153	1	NUP88	1	affinity chromatography technology	Hein MY (2015)	1
NUP107	1	KPNB1	3	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Walther TC (2003), Kim DI (2014), Hein MY (2015), Hein MY (2015)	4
NUP62	1	RANBP2	9	pull down, affinity chromatography technology	Stochaj U (2006), Stochaj U (2006)	2
KPNB1	3	SMAD4	9	affinity chromatography technology	Xiao Z (2000)	1
CUL3	17	NUP214	3	affinity chromatography technology	Bennett EJ (2010)	1
STRIP1	3	NUP214	3	biochemical	Havugimana PC (2012)	1
UBE2I	0	NUP214	3	affinity chromatography technology	Hein MY (2015)	1
HSPA1L	2	RANBP2	9	biochemical	Havugimana PC (2012)	1
CUL7	4	RANBP2	9	affinity chromatography technology	Hanson D (2014)	1
BRCA1	7	IPO5	0	affinity chromatography technology	Ertych N (2016)	1
KPNB1	3	RAN	1	far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Kutay U (1997), Percipalle P (1997), Plafker K (2000), Ciciarello M (2010), Hieda M (1999), Hieda M (1999), Kutay U (2000), Kutay U (2000), Chi NC (1996), Chi NC (1996), Lipowsky G (2000), Chi NC (1997), Havugimana PC (2012), Goerlich D (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	17
BRCA1	7	NUP153	1	unspecified method, affinity chromatography technology	Rodriguez M (2003), Ertych N (2016)	2
SERPINB2	0	NUP214	3	affinity chromatography technology	Huttlin EL (2017)	1
FXR2	2	G3BP1	4	affinity chromatography technology, affinity chromatography technology	Li S (2014), Jain S (2016)	2
XPO1	8	NUP62	1	affinity chromatography technology, pull down, affinity chromatography technology	Kehlenbach RH (1999), Kehlenbach RH (1999), Lindsay ME (2001)	3
NTRK1	1	IPO5	0	affinity chromatography technology	Emdal KB (2015)	1
NXF1	0	VPS4B	3	affinity chromatography technology	Castello A (2012)	1
NUP107	1	XPO1	8	bioid	Kim DI (2014)	1
SEH1L	1	NUP214	3	affinity chromatography technology	Hein MY (2015)	1
APC	5	11097	0	two hybrid	Bandyopadhyay S (2010)	1
NUP107	1	11097	0	affinity chromatography technology	Hein MY (2015)	1
EEF1A1	0	RANBP2	9	biochemical	Havugimana PC (2012)	1
OBSL1	9	NUP85	6	affinity chromatography technology	Hanson D (2014)	1
NUP107	1	NUP88	1	affinity chromatography technology	Hein MY (2015)	1
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
NUP35	0	11097	0	bioid	Kim DI (2014)	1
BRCA1	7	RAN	1	affinity chromatography technology	Ertych N (2016)	1
ITGA4	4	LMNA	2	affinity chromatography technology	Byron A (2012)	1
SOX2	4	XPO1	8	pull down	Baltus GA (2009)	1
SIRT7	1	NUP107	1	affinity chromatography technology	Tsai YC (2012)	1
CUL2	3	HSPA1L	2	affinity chromatography technology	Bennett EJ (2010)	1
NXF1	0	NUP62	1	pull down, pull down, two hybrid, pull down, two hybrid	Levesque L (2006), Levesque L (2006), Rolland T (2014), Herold A (2000), Yu H (2011)	5
NUP85	6	NUP214	3	bioid	Kim DI (2014)	1
SEH1L	1	NUP85	6	affinity chromatography technology, bioid, affinity chromatography technology	Loiodice I (2004), Kim DI (2014), Hein MY (2015)	3
XPO1	8	KCMF1	0	affinity chromatography technology	Kirli K (2015)	1
RANBP2	9	RAN	1	pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Yaseen NR (1999), Liu C (2010), Yokoyama N (1995), Yokoyama N (1995), Wang J (2011), Nishitani H (2001), Wan C (2015), Huttlin EL (2017)	8
CUL2	3	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
DDX19A	0	NUP214	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD4	9	EEF1A1	0	two hybrid	Colland F (2004)	1
ACOT13	0	NUP214	3	biochemical	Havugimana PC (2012)	1
KPNB1	3	IPO5	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
NUP35	0	RANBP2	9	bioid	Kim DI (2014)	1
OBSL1	9	NUP62	1	affinity chromatography technology	Hanson D (2014)	1
OBSL1	9	KPNB1	3	affinity chromatography technology	Hanson D (2014)	1
NUP58	0	NUP214	3	affinity chromatography technology	Hein MY (2015)	1
CUL7	4	IPO5	0	affinity chromatography technology	Hanson D (2014)	1
G3BP2	4	G3BP1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Jain S (2016)	3
NTRK1	1	LMNA	2	affinity chromatography technology	Emdal KB (2015)	1
IFI16	1	NUP85	6	affinity chromatography technology	Diner BA (2015)	1
HDAC5	4	XPO1	8	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Kirli K (2015)	2
CUL3	17	FXR2	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	NUP88	1	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	FXR2	2	affinity chromatography technology	Emdal KB (2015)	1
BRCA1	7	IFI16	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Aglipay JA (2003), Dutta D (2015), Dutta D (2015), Dutta D (2015)	4
SIRT7	1	XPO5	2	affinity chromatography technology	Tsai YC (2012)	1
CUL2	3	NUP214	3	affinity chromatography technology	Bennett EJ (2010)	1
SIRT7	1	NUP153	1	affinity chromatography technology	Tsai YC (2012)	1
CUL3	17	RAE1	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2I	0	TRIM28	1	affinity chromatography technology, pull down, enzymatic study, pull down	Liang Q (2011), Garvin AJ (2013), Ivanov AV (2007), Neo SH (2015)	4
FBXO6	0	EEF1A1	0	affinity chromatography technology	Liu B (2012)	1
NXF1	0	PNPT1	1	affinity chromatography technology	Castello A (2012)	1
CUL3	17	HSPA1L	2	affinity chromatography technology	Bennett EJ (2010)	1
NUP107	1	RANBP2	9	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
IFI16	1	NUP58	0	affinity chromatography technology	Diner BA (2015)	1
NTRK1	1	CUL2	3	affinity chromatography technology	Emdal KB (2015)	1
APC	5	RANBP2	9	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Murawala P (2009), Novellasdemunt L (2017)	3
SEH1L	1	NXF1	0	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	NUP62	1	affinity chromatography technology	Bennett EJ (2010)	1
NUP88	1	NUP62	1	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
SMAD2	5	EEF1A1	0	two hybrid	Colland F (2004)	1
UBE2I	0	NUP85	6	affinity chromatography technology	Hein MY (2015)	1
NXF1	0	STRIP1	3	affinity chromatography technology	Castello A (2012)	1
CUL7	4	RPL19	1	affinity chromatography technology	Hanson D (2014)	1
LMNA	2	NUP153	1	bioid, bioid	Roux KJ (2012), Kim DI (2014)	2
OBSL1	9	LMNA	2	affinity chromatography technology	Hanson D (2014)	1
NXF1	0	NUP153	1	pull down, affinity chromatography technology	Herold A (2000), Hein MY (2015)	2
NTRK1	1	STRIP1	3	affinity chromatography technology	Emdal KB (2015)	1
LMNA	2	SMAD1	0	two hybrid	Dittmer TA (2014)	1
IFI16	1	NUP62	1	affinity chromatography technology	Diner BA (2015)	1
FBXO6	0	KPNB1	3	affinity chromatography technology	Liu B (2012)	1
FBXO6	0	TRIM28	1	affinity chromatography technology	Liu B (2012)	1
CDH1	4	LMNA	2	affinity chromatography technology	Catimel B (2005)	1
DDX19A	0	NUP88	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SEH1L	1	NUP107	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Loiodice I (2004), Kaur S (2010), Glavy JS (2007), Kim DI (2014), Hein MY (2015), Hein MY (2015)	6
KCMF1	0	NUP214	3	affinity chromatography technology	Hong JH (2015)	1
NUP107	1	NUP153	1	biochemical, biochemical, bioid, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Kim DI (2014), Hein MY (2015), Hein MY (2015)	5
KPNB1	3	SEH1L	1	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	XPO5	2	affinity chromatography technology	Emdal KB (2015)	1
CLEC11A	0	NUP214	3	affinity chromatography technology	Huttlin EL (2015)	1
UBE2I	0	RANBP2	9	affinity chromatography technology, pull down, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Zhang H (2002), Bandyopadhyay S (2010), Werner A (2012), Tatham MH (2005), Saitoh H (2002), Saitoh H (2002), Gareau JR (2012), Hein MY (2015), Sarkar K (2015), Huttlin EL (2017)	11
EMSY	3	NUP88	1	affinity chromatography technology	Varier RA (2016)	1
NUP214	3	NXF2	0	pull down, pull down, affinity chromatography technology	Herold A (2000), Herold A (2000), Huttlin EL (2017)	3
NUP214	3	NUP214	3	pull down	Katahira J (1999)	1
NTRK1	1	DYNC1LI1	1	affinity chromatography technology	Emdal KB (2015)	1
G3BP1	4	NUP214	3	affinity chromatography technology	Sowa ME (2009)	1
CUL7	4	LMNA	2	affinity chromatography technology	Hanson D (2014)	1
BRCA1	7	HSPA1L	2	affinity chromatography technology	Ertych N (2016)	1
NUP35	0	NUP153	1	bioid, affinity chromatography technology	Kim DI (2014), Hein MY (2015)	2
NUP214	3	TXNDC9	0	biochemical	Wan C (2015)	1
OBSL1	9	NUP58	0	affinity chromatography technology	Hanson D (2014)	1
NUP85	6	NUP88	1	bioid	Kim DI (2014)	1
FXR2	2	NUP214	3	affinity chromatography technology	Huttlin EL (2017)	1
UBE2I	0	LMNA	2	two hybrid, affinity chromatography technology, enzymatic study	Zhong N (2005), Zhong N (2005), Matafora V (2009)	3
G3BP1	4	DDX19A	0	affinity chromatography technology	Jain S (2016)	1
OBSL1	9	CUL7	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Litterman N (2011), Litterman N (2011), Hanson D (2011), Hanson D (2011), Nie J (2015)	5
NTRK1	1	CFL1	0	affinity chromatography technology	Emdal KB (2015)	1
RANBP2	9	NUP153	1	affinity chromatography technology, affinity chromatography technology	Yokoyama N (1995), Hein MY (2015)	2
XPO1	8	SMAD4	9	affinity chromatography technology	Kirli K (2015)	1
CUL7	4	RAN	1	affinity chromatography technology	Hanson D (2014)	1
HDAC5	4	UBE2I	0	two hybrid	Zhao X (2005)	1
IFI16	1	SEH1L	1	affinity chromatography technology	Diner BA (2015)	1
OBSL1	9	NUP35	0	affinity chromatography technology	Hanson D (2014)	1
SMAD2	5	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe	Brown KA (2008), Wu RY (1997), Wu RY (1997), Ivanov AA (2017)	4
OBSL1	9	RANBP2	9	affinity chromatography technology	Hanson D (2014)	1
HDAC9	7	HDAC4	10	pull down	Petrie K (2003)	1
UBE2I	0	KPNB1	3	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
CUL3	17	IPO5	0	affinity chromatography technology	Bennett EJ (2010)	1