Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
SLC14A2 8170 NIFEDIPINE CHEMBL193 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SLC14A2 rs12456693 CT clopidogrel metabolism/PK no The CT genotype was associated with increased active metabolite H4 concentration. However, it was not statistically significant. Genotype CT is associated with increased metabolism of clopidogrel as compared to genotype CC. 27981573 1448624885
SLC14A2 rs12456693 T clopidogrel efficacy yes This variant is associated with increased H4 concentration. Allele T is associated with increased response to clopidogrel in people with Coronary Artery Disease as compared to allele C. 30487649 1450123149