PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
OTUD4	2	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao Y (2015), Zhao Y (2015), Zhao Y (2015)	3
UBE2V2	0	UBC	7	x-ray crystallography, pull down, x-ray crystallography, x-ray crystallography, pull down	McKenna S (2003), McKenna S (2003), McKenna S (2003), Lewis MJ (2006), McKenna S (2001)	5
CAND1	2	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
LATS1	3	PTPN14	5	bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Wilson KE (2014), Wilson KE (2014)	3
NTRK1	1	WWP2	7	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	RPTOR	4	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	UBE2C	1	affinity chromatography technology	Matsumoto M (2005)	1
POU5F1	0	USP34	7	affinity chromatography technology	Oliviero G (2015)	1
CDH1	4	TRIM25	5	bioid	Guo Z (2014)	1
XPO1	8	NFX1	2	affinity chromatography technology	Kirli K (2015)	1
USP34	7	UFM1	0	biochemical	Havugimana PC (2012)	1
SMAD2	5	USP9X	15	affinity chromatography technology	Dupont S (2009)	1
UBE2V2	0	USP34	7	biochemical	Havugimana PC (2012)	1
LATS1	3	USP9X	15	affinity chromatography technology, biochemical	Toloczko A (2017), Toloczko A (2017)	2
PJA1	1	UBE2L3	1	pull down	Zoabi M (2011)	1
UBXN1	0	UNK	3	biochemical	Havugimana PC (2012)	1
SSSCA1	0	UBXN1	0	biochemical	Havugimana PC (2012)	1
XPO1	8	RPTOR	4	affinity chromatography technology	Kirli K (2015)	1
MALT1	1	SUV39H1	0	two hybrid	Weimann M (2013)	1
SMN2	0	SNRPB	0	pull down, affinity chromatography technology	Buehler D (1999), Han KJ (2012)	2
NUBP2	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
SMURF1	4	UBE2D2	0	pull down, pull down	Kristariyanto YA (2015), Andrews PS (2010)	2
AFDN	10	USP9X	15	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Taya S (1999), Taya S (1998), Taya S (1998), Taya S (1998)	4
CTNNB1	30	HDAC6	0	affinity chromatography technology	Li Y (2008)	1
TRIM25	5	ZYX	2	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	NUBP2	0	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	SSSCA1	0	affinity chromatography technology	Rodriguez J (2016)	1
SUV39H1	0	USP34	7	affinity chromatography technology	Huttlin EL (2017)	1
SMURF1	4	UBE2D1	0	pull down, enzymatic study	Kristariyanto YA (2015), Andrews PS (2010)	2
AHCYL1	2	SRXN1	0	biochemical	Havugimana PC (2012)	1
SAV1	0	PTPN14	5	bioid	Couzens AL (2013)	1
UBQLN1	1	UNK	3	biochemical	Havugimana PC (2012)	1
UBE4B	5	UBL7	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huttlin EL (2017)	4
TERF2	2	USP9X	15	affinity chromatography technology	Giannone RJ (2010)	1
EGLN3	0	YAP1	0	affinity chromatography technology	Rodriguez J (2016)	1
HDAC6	0	USP9X	15	affinity chromatography technology	Joshi P (2013)	1
USP9X	15	MARCH7	0	affinity chromatography technology, affinity chromatography technology	Agrawal P (2012), Nathan JA (2008)	2
USP9X	15	CCT4	2	biochemical	Kristensen AR (2012)	1
UBQLN1	1	UBXN1	0	biochemical, two hybrid	Havugimana PC (2012), Rolland T (2014)	2
ECT2	2	AHCYL1	2	affinity chromatography technology	Woods NT (2012)	1
UBA52	0	UFC1	0	biochemical	Havugimana PC (2012)	1
UFC1	0	USP9X	15	biochemical	Havugimana PC (2012)	1
UBC	7	MIB1	5	affinity chromatography technology	Matsumoto M (2005)	1
ELP1	5	USP9X	15	affinity chromatography technology	Johansen LD (2008)	1
HDAC5	4	USP9X	15	affinity chromatography technology	Greco TM (2011)	1
XPO1	8	CSNK1E	0	affinity chromatography technology	Kirli K (2015)	1
UNK	3	USP9X	15	biochemical, affinity chromatography technology	Havugimana PC (2012), Murn J (2015)	2
NTRK1	1	ZNF598	6	affinity chromatography technology	Emdal KB (2015)	1
SAV1	0	USP9X	15	affinity chromatography technology, affinity chromatography technology	Toloczko A (2017), Toloczko A (2017)	2
ERG	1	UBR4	15	pull down	Wang S (2016)	1
CAND1	2	SEC23A	3	biochemical	Kristensen AR (2012)	1
UBE2V2	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
PTPN14	5	WWP2	7	affinity chromatography technology, affinity chromatography technology	Wang W (2012), Chaudhary N (2014)	2
IGBP1	1	UBE4B	5	biochemical	Havugimana PC (2012)	1
AURKA	1	LATS2	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, fluorescent resonance energy transfe	Yabuta N (2011), Toji S (2004), Toji S (2004), Toji S (2004), Toji S (2004), Ivanov AA (2017)	6
UBQLN2	0	YAP1	0	biochemical	Havugimana PC (2012)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
UBE4B	5	UCHL3	1	biochemical	Havugimana PC (2012)	1
USP9X	15	ZYX	2	biochemical	Havugimana PC (2012)	1
CDH1	4	ECT2	2	affinity chromatography technology	Liot C (2011)	1
AHCYL1	2	ZYX	2	biochemical	Havugimana PC (2012)	1
UBE2B	3	UBR4	15	affinity chromatography technology	Hong JH (2015)	1
SIRT7	1	SNRNP200	15	affinity chromatography technology	Tsai YC (2012)	1
HDAC6	0	TCP1	0	affinity chromatography technology	New M (2013)	1
USP9X	15	DDX20	4	affinity chromatography technology, affinity chromatography technology	Han KJ (2012), Han KJ (2012)	2
UBE2D1	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
HDAC5	4	TCP1	0	affinity chromatography technology	Greco TM (2011)	1
AHCYL1	2	UBL7	0	biochemical	Havugimana PC (2012)	1
SIRT7	1	HUWE1	22	affinity chromatography technology	Tsai YC (2012)	1
TRIM25	5	USP34	7	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	UBR4	15	affinity chromatography technology	Rodriguez J (2016)	1
MCM2	3	SEC23A	3	affinity chromatography technology	Drissi R (2015)	1
VHL	0	USP9X	15	affinity chromatography technology, affinity chromatography technology, pull down	Zhang C (2016), Zhang C (2016), Zhang C (2016)	3
NTRK1	1	UBE4B	5	affinity chromatography technology	Emdal KB (2015)	1
UBQLN2	0	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chang L (2015), Hjerpe R (2016), Hjerpe R (2016)	3
UBXN7	3	USP9X	15	biochemical	Havugimana PC (2012)	1
PCGF1	1	DPPA4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Oliviero G (2015), Oliviero G (2015), Oliviero G (2015), Oliviero G (2015), Oliviero G (2015)	5
EGFR	5	PSMA4	0	affinity chromatography technology	Yao Z (2017)	1
PCGF1	1	USP34	7	affinity chromatography technology	Oliviero G (2015)	1
SIRT7	1	USP34	7	affinity chromatography technology	Tsai YC (2012)	1
SIRT7	1	UBR4	15	affinity chromatography technology	Tsai YC (2012)	1
GEMIN5	1	GEMIN8	1	affinity chromatography technology	Hein MY (2015)	1
CFTR	5	RUVBL1	2	affinity chromatography technology	Pankow S (2015)	1
UBXN7	3	UFC1	0	biochemical	Havugimana PC (2012)	1
SMURF1	4	XPO1	8	affinity chromatography technology	Tajima Y (2003)	1
MCM2	3	UBA52	0	affinity chromatography technology	Drissi R (2015)	1
XPO1	8	GPSM1	1	affinity chromatography technology	Kirli K (2015)	1
SNCA	0	EFTUD2	12	affinity chromatography technology	Hein MY (2015)	1
EGLN3	0	IQCB1	3	affinity chromatography technology	Rodriguez J (2016)	1
AHCYL1	2	UBE2B	3	biochemical	Havugimana PC (2012)	1
SMAD3	1	SUV39H1	0	affinity chromatography technology	Wakabayashi Y (2011)	1
AHCYL1	2	UBQLN1	1	biochemical	Havugimana PC (2012)	1
GRK5	7	USP9X	15	affinity chromatography technology	Wu Z (2012)	1
TTLL12	3	USP9X	15	biochemical	Havugimana PC (2012)	1
MCM2	3	TCP1	0	affinity chromatography technology	Drissi R (2015)	1
NTRK1	1	MIB1	5	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	GPSM1	1	affinity chromatography technology	Emdal KB (2015)	1
PTPN21	10	USP9X	15	affinity chromatography technology	St-Denis N (2016)	1
SUV39H1	0	CCT4	2	affinity chromatography technology	Hauri S (2016)	1
HDAC5	4	RUVBL1	2	affinity chromatography technology	Greco TM (2011)	1
UBXN1	0	HUWE1	22	affinity chromatography technology	Alexandru G (2008)	1
SEC23A	3	UBXN7	3	biochemical	Havugimana PC (2012)	1
TERF1	1	MCM2	3	two hybrid	Lee OH (2011)	1
POU5F1	0	WWP2	7	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu H (2009), Xu H (2009), Xu H (2009), Qian YW (2012), Liao B (2010)	5
AHCYL1	2	SEC24C	2	biochemical	Havugimana PC (2012)	1
SNRNP200	15	USP34	7	biochemical	Kristensen AR (2012)	1
XPO1	8	PJA1	1	affinity chromatography technology	Kirli K (2015)	1
CFTR	5	XPO1	8	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
TTLL12	3	UBE2D1	0	biochemical	Havugimana PC (2012)	1
UBE2D1	0	UBE2B	3	biochemical	Havugimana PC (2012)	1
RASSF10	2	USP9X	15	affinity chromatography technology	Hauri S (2013)	1
NTRK1	1	UBQLN2	0	affinity chromatography technology	Emdal KB (2015)	1
HUWE1	22	UBE2L3	1	pull down, pull down, pull down, pull down, pull down, pull down	Pandya RK (2010), Parsons JL (2009), Schwarz SE (1998), Kristariyanto YA (2015), Choe KN (2016), Kurokawa M (2013)	6
XPO1	8	ZYX	2	affinity chromatography technology	Kirli K (2015)	1
EFTUD2	12	SNRNP200	15	two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Liu S (2006), Liu S (2006), Havugimana PC (2012), Guo R (2014), Wan C (2015), Boldt K (2016)	6
EGFR	5	ITCH	1	affinity chromatography technology	Tong J (2014)	1
HDAC5	4	SNRNP200	15	affinity chromatography technology	Greco TM (2011)	1
BIRC2	1	UBE2D1	0	affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Hu S (2003), Dynek JN (2010), Dynek JN (2010), Xu M (2009), Phu L (2011), Oberoi TK (2012), Bertrand MJ (2011), Guicciardi ME (2014), Takeda AN (2014), Wauer T (2015), Vu NT (2016)	11
RPS6KB2	3	USP9X	15	affinity chromatography technology	Roy R (2014)	1
EGLN3	0	PSMA4	0	affinity chromatography technology	Rodriguez J (2016)	1
ZNF598	6	IRS4	2	affinity chromatography technology	Garzia A (2017)	1
USP34	7	UFC1	0	biochemical	Havugimana PC (2012)	1
GRK5	7	OTUD4	2	affinity chromatography technology	Wu Z (2012)	1
EFTUD2	12	UBR4	15	biochemical	Havugimana PC (2012)	1
SUV39H1	0	TCP1	0	affinity chromatography technology	Hauri S (2016)	1
AMOT	6	YAP1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Wang C (2012), Wang C (2012), Adler JJ (2013), Couzens AL (2013), Adler JJ (2013), Chan SW (2013), Dai X (2013), Hauri S (2013)	9
TERF2	2	HEXIM2	0	two hybrid	Lee OH (2011)	1
TRIM25	5	ELP1	5	affinity chromatography technology	Choudhury NR (2017)	1
CRY2	2	CAND1	2	affinity chromatography technology	Papp SJ (2015)	1
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
ECT2	2	USP9X	15	affinity chromatography technology	Woods NT (2012)	1
HDAC5	4	EFTUD2	12	affinity chromatography technology	Greco TM (2011)	1
SIRT7	1	DDX20	4	affinity chromatography technology	Tsai YC (2012)	1
UBE4B	5	UFM1	0	biochemical	Havugimana PC (2012)	1
HUWE1	22	PSMA4	0	affinity chromatography technology	Thompson JW (2014)	1
IRS4	2	MAGED1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGFR	5	USP9X	15	affinity chromatography technology	Foerster S (2013)	1
MARCH7	0	UBE2D2	0	pull down	Flach K (2014)	1
XPO1	8	SEC23A	3	affinity chromatography technology	Kirli K (2015)	1
NANOG	0	SNRPB	0	affinity chromatography technology	Oliviero G (2015)	1
LATS1	3	YAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Zhang J (2008), Zhang J (2008), Ho KC (2011), Vigneron AM (2010), Vigneron AM (2010), Huntoon CJ (2010), Hao Y (2008), Hao Y (2008), Hao Y (2008), Hao Y (2008), Matallanas D (2007), Matallanas D (2007), Oka T (2008), Oka T (2008), Oka T (2008), Yu FX (2012), Yu FX (2012), Chiyoda T (2012), Couzens AL (2013), Ho KC (2011), Salah Z (2013), Hauri S (2013), Schuchardt BJ (2014), Mei L (2017), Enzo E (2015), Si Y (2017), Guo PD (2016)	27
EGLN3	0	ELP1	5	affinity chromatography technology	Rodriguez J (2016)	1
SSSCA1	0	UBE2V2	0	biochemical	Havugimana PC (2012)	1
CTNNB1	30	PTPN14	5	affinity chromatography technology, affinity chromatography technology	Wadham C (2003), Wadham C (2003)	2
TTLL12	3	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
CFTR	5	SEC24C	2	affinity chromatography technology	Pankow S (2015)	1
CFTR	5	CAND1	2	affinity chromatography technology	Wang X (2006)	1
WWC1	5	AMOTL1	3	affinity chromatography technology	Toloczko A (2017)	1
UBE2L3	1	USP34	7	biochemical	Havugimana PC (2012)	1
POU5F1	0	UBR4	15	affinity chromatography technology	Oliviero G (2015)	1
SRXN1	0	UBE2B	3	biochemical	Havugimana PC (2012)	1
UBL7	0	ZYX	2	biochemical	Havugimana PC (2012)	1
SOD1	0	UFM1	0	biochemical	Wan C (2015)	1
YAP1	0	SMAD2	5	affinity chromatography technology	Pefani DE (2016)	1
TRIM25	5	MARK4	6	affinity chromatography technology	Choudhury NR (2017)	1
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
SRXN1	0	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
GEMIN5	1	GEMIN4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gubitz AK (2002), Piazzon N (2012), Hein MY (2015)	3
UBXN1	0	UBC	7	pull down, pull down, affinity chromatography technology, pull down, pull down, pull down	Wu-Baer F (2010), Fenner BJ (2009), Alexandru G (2008), LaLonde DP (2011), McNeill H (2004), Zhang X (2017)	6
UBC	7	RUVBL1	2	affinity chromatography technology	Matsumoto M (2005)	1
EGFR	5	ELP1	5	affinity chromatography technology	Tong J (2014)	1
UBXN7	3	BIRC2	1	affinity chromatography technology	Alexandru G (2008)	1
EGLN3	0	MIB1	5	affinity chromatography technology	Rodriguez J (2016)	1
SEC24C	2	USP9X	15	biochemical	Havugimana PC (2012)	1
OTUD4	2	UBC	7	enzymatic study, enzymatic study, pull down, pull down	Mevissen TE (2013), Zhao Y (2015), Zhang X (2017), Kwasna D (2018)	4
SSSCA1	0	AURKA	1	biochemical	Havugimana PC (2012)	1
BIRC3	1	BIRC5	1	pull down	Dohi T (2004)	1
CUL3	17	AURKA	1	affinity chromatography technology	Moghe S (2012)	1
UBE2C	1	YAP1	0	biochemical	Havugimana PC (2012)	1
LNX1	7	SUV39H1	0	two hybrid	Weimann M (2013)	1
NANOG	0	KIAA0368	0	affinity chromatography technology	Oliviero G (2015)	1
CFTR	5	TES	1	affinity chromatography technology	Pankow S (2015)	1
TCP1	0	CCT4	2	affinity chromatography technology, biochemical, biochemical, biochemical	Gingras AC (2005), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	4
UBXN1	0	MAGED1	0	affinity chromatography technology	Raman M (2015)	1
AHCYL1	2	TTLL12	3	biochemical	Havugimana PC (2012)	1
WWP2	7	UBC	7	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Sheng Y (2012), Maspero E (2013), Soond SM (2013), Kristariyanto YA (2015)	4
TRIM25	5	EFTUD2	12	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
YAP1	0	PTPN21	10	pull down, affinity chromatography technology	Li X (2016), Li X (2016)	2
SNRNP200	15	PRPF8	14	two hybrid, two hybrid, biochemical, x-ray crystallography, two hybrid, biochemical, affinity chromatography technology	Liu S (2006), Liu S (2006), Havugimana PC (2012), Mozaffari-Jovin S (2013), Pena V (2007), Wan C (2015), Boldt K (2016)	7
NTRK1	1	ELP1	5	affinity chromatography technology	Emdal KB (2015)	1
DDX20	4	SMN2	0	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Han KJ (2012), Huttlin EL (2017)	3
HDAC6	0	XPO1	8	affinity chromatography technology, affinity chromatography technology	Riolo MT (2012), Kirli K (2015)	2
YAP1	0	ZYX	2	affinity chromatography technology	Enzo E (2015)	1
SOX2	4	UBR4	15	affinity chromatography technology	Cox JL (2013)	1
TRIM25	5	CTNNB1	30	affinity chromatography technology	Choudhury NR (2017)	1
AHCYL1	2	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
UBE2D2	0	TRIM25	5	two hybrid, pull down, pull down, pull down, affinity chromatography technology	Markson G (2009), Nakajima A (2007), Ronchi VP (2012), Sanchez JG (2016), Choudhury NR (2017)	5
POU5F1	0	PCGF1	1	affinity chromatography technology	Oliviero G (2015)	1
TTLL12	3	UBE2V2	0	biochemical	Havugimana PC (2012)	1
UBE4B	5	UBE2D2	0	pull down, pull down, pull down	Benirschke RC (2010), Wu H (2011), Buetow L (2015)	3
ZNF263	2	AHCYL1	2	affinity chromatography technology	Huttlin EL (2017)	1
USP9X	15	RUVBL1	2	affinity chromatography technology	Agrawal P (2012)	1
CFTR	5	PSMA4	0	affinity chromatography technology	Pankow S (2015)	1
NTRK1	1	EFTUD2	12	affinity chromatography technology	Emdal KB (2015)	1
GPSM1	1	USP9X	15	affinity chromatography technology, pull down	Xu Z (2010), Xu Z (2010)	2
CSNK1E	0	CRY2	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
USP9X	15	GEMIN2	1	affinity chromatography technology, affinity chromatography technology	Han KJ (2012), Han KJ (2012)	2
BIRC5	1	USP9X	15	affinity chromatography technology	Vong QP (2005)	1
USP9X	15	SNRPB	0	affinity chromatography technology	Han KJ (2012)	1
XPO1	8	GEMIN2	1	affinity chromatography technology	Kirli K (2015)	1
EGLN3	0	RPTOR	4	affinity chromatography technology	Rodriguez J (2016)	1
RUVBL1	2	EFTUD2	12	affinity chromatography technology	Cloutier P (2017)	1
SOD1	0	UFC1	0	biochemical	Wan C (2015)	1
AURKA	1	BIRC5	1	affinity chromatography technology, enzymatic study	Fu J (2009), Fu J (2009)	2
UFC1	0	ZYX	2	biochemical	Havugimana PC (2012)	1
GRK5	7	EFTUD2	12	affinity chromatography technology	Wu Z (2012)	1
CFTR	5	CDH1	4	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
TTLL12	3	UFM1	0	biochemical	Havugimana PC (2012)	1
MTOR	14	RPTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Schalm SS (2003), Hara K (2002), Ha SH (2006), Wang L (2006), Frias MA (2006), Frias MA (2006), Buerger C (2006), Jacinto E (2006), McMahon LP (2005), Oshiro N (2004), Kawai S (2003), Choi KM (2003), Hara K (2002), Hara K (2002), Kim DH (2002), Kim DH (2002), Schieke SM (2006), Ha SH (2006), Wang L (2006), Frias MA (2006), Buerger C (2006), Sarbassov DD (2006), Tzatsos A (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Kwak D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Wu D (2012), Gwinn DM (2010), Sancak Y (2007), Sancak Y (2007), Yang Q (2006), Carriere A (2011), Jacinto E (2006), Rosner M (2010), Kim DH (2003), Kim DH (2003), Carriere A (2008), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Hussain S (2013), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Yan X (2012), Ramirez-Rangel I (2011), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Linares JF (2013), Coffman K (2014), Oshiro N (2014), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), Dan HC (2008), Dan HC (2008), Dan HC (2008), Hong F (2008), Hong F (2008), Choo AY (2008), Toschi A (2009), Loewith R (2002), Xu Y (2013), Sancak Y (2010), Sancak Y (2010), Vander Haar E (2007), Vander Haar E (2007), Kaadige MR (2015), Misra UK (2014), Misra UK (2014), Thedieck K (2007), Thomas JD (2014), Park D (2014), Alayev A (2016), Alayev A (2016)	91
LATS2	1	LATS1	3	affinity chromatography technology, bioid	Xiao L (2011), Couzens AL (2013)	2
MTOR	14	RUVBL1	2	affinity chromatography technology	Agrawal P (2012)	1
UCHL3	1	USP9X	15	biochemical	Havugimana PC (2012)	1
NANOG	0	DDX20	4	affinity chromatography technology	Oliviero G (2015)	1
RPS6KB2	3	TCP1	0	affinity chromatography technology	Roy R (2014)	1
SMURF1	4	TCP1	0	affinity chromatography technology	Xie Y (2013)	1
NTRK1	1	TTLL12	3	affinity chromatography technology	Emdal KB (2015)	1
ZNF598	6	XPO1	8	affinity chromatography technology	Garzia A (2017)	1
UFM1	0	USP9X	15	biochemical	Havugimana PC (2012)	1
NTRK1	1	SEC24C	2	affinity chromatography technology	Emdal KB (2015)	1
GEMIN2	1	GEMIN8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Piazzon N (2012), Piazzon N (2012), Huttlin EL (2017)	3
AHCYL1	2	UFC1	0	biochemical	Havugimana PC (2012)	1
WWC1	5	LATS1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xiao L (2011), Xiao L (2011), Wilson KE (2014), Wilson KE (2014), Wennmann DO (2014)	5
ZNF598	6	RUVBL1	2	affinity chromatography technology	Garzia A (2017)	1
USP34	7	UBQLN1	1	biochemical	Havugimana PC (2012)	1
DDX20	4	GEMIN5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gubitz AK (2002), Gubitz AK (2002), Mourelatos Z (2002), Piazzon N (2012), Mirabella F (2014), Hein MY (2015), Huttlin EL (2017)	7
YAP1	0	AMOTL1	3	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Couzens AL (2013), Hauri S (2013), Enzo E (2015)	4
HDAC6	0	UBC	7	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Pai MT (2007), Pozo FM (2011), Sekimoto T (2010), Kovacs JJ (2004), Hao R (2013), Lee JH (2013), Nakashima H (2014), Banerjee I (2014), Hao R (2013), Zhang X (2017), Yu Q (2018)	11
UCHL3	1	ZYX	2	biochemical	Havugimana PC (2012)	1
EGLN3	0	BIRC3	1	affinity chromatography technology	Fu J (2016)	1
SSSCA1	0	UBE2D1	0	biochemical	Havugimana PC (2012)	1
ALKBH3	1	CCT4	2	affinity chromatography technology	Zhao Y (2015)	1
NTRK1	1	SEC23A	3	affinity chromatography technology	Emdal KB (2015)	1
SSSCA1	0	UBQLN1	1	biochemical	Havugimana PC (2012)	1
SOD1	0	USP9X	15	affinity chromatography technology	Hein MY (2015)	1
UBXN1	0	USP9X	15	biochemical	Havugimana PC (2012)	1
ASB15	1	USP9X	15	affinity chromatography technology	Andresen CA (2014)	1
USP9X	15	CTNNB1	30	affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Taya S (1999), Taya S (1999), Taya S (1999), Murray RZ (2004), Yang B (2016), Yang B (2016)	6
UBC	7	PJA1	1	affinity chromatography technology	Matsumoto M (2005)	1
SIRT7	1	ELP1	5	affinity chromatography technology	Tsai YC (2012)	1
SMAD2	5	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NANOG	0	MCM2	3	affinity chromatography technology	Oliviero G (2015)	1
CRY1	0	RUVBL1	2	affinity chromatography technology	Papp SJ (2015)	1
RPS6KB2	3	SNRPB	0	affinity chromatography technology	Roy R (2014)	1
LATS2	1	AMOT	6	affinity chromatography technology, bioid, enzymatic study, enzymatic study, enzymatic study	Couzens AL (2013), Couzens AL (2013), Adler JJ (2013), Chan SW (2013), Dai X (2013)	5
SSSCA1	0	USP34	7	biochemical	Havugimana PC (2012)	1
BCL10	0	UBE2V2	0	pull down	Zhou H (2004)	1
BIRC2	1	EGFR	5	affinity chromatography technology	Puliyappadamba VT (2013)	1
EGLN3	0	MAGED4	0	affinity chromatography technology	Rodriguez J (2016)	1
AURKA	1	CTNNB1	30	affinity chromatography technology	Hein MY (2015)	1
BIRC2	1	UBE2L3	1	affinity chromatography technology	Hu S (2003)	1
UBE2V2	0	UBE2B	3	biochemical	Havugimana PC (2012)	1
WWC1	5	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Toloczko A (2017), Toloczko A (2017), Toloczko A (2017)	3
TRIM25	5	PRPF8	14	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	MAGED1	0	affinity chromatography technology	Emdal KB (2015)	1
IRS4	2	USP9X	15	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
UBE2D1	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
LATS1	3	AMOTL1	3	bioid	Couzens AL (2013)	1
SMAD3	1	TCP1	0	affinity chromatography technology	Brown KA (2008)	1
TES	1	ZYX	2	pull down, affinity chromatography technology, affinity chromatography technology	Garvalov BK (2003), Huttlin EL (2017), Sala S (2017)	3
PSMA4	0	PSMB4	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Nandi D (1997), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
CUL3	17	SEC24C	2	affinity chromatography technology	Bennett EJ (2010)	1
IGBP1	1	NUDCD2	2	biochemical	Havugimana PC (2012)	1
SEC23A	3	UBQLN2	0	biochemical	Havugimana PC (2012)	1
UBXN7	3	UCHL3	1	biochemical	Havugimana PC (2012)	1
SMAD3	1	USP9X	15	affinity chromatography technology	Dupont S (2009)	1
UBE4B	5	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
NTRK1	1	RUVBL1	2	affinity chromatography technology	Emdal KB (2015)	1
MCM2	3	TRIM25	5	affinity chromatography technology	Drissi R (2015)	1
EGFR	5	SNCA	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
NUAK1	2	USP9X	15	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Al-Hakim AK (2008), Al-Hakim AK (2008), Al-Hakim AK (2008), Banerjee S (2014)	4
AMOT	6	CTNNB1	30	bioid	Couzens AL (2013)	1
ALKBH3	1	TCP1	0	affinity chromatography technology	Zhao Y (2015)	1
TRIM25	5	UBQLN1	1	affinity chromatography technology	Choudhury NR (2017)	1
SOD1	0	HDAC6	0	affinity chromatography technology	Gal J (2013)	1
USP9X	15	GEMIN4	2	affinity chromatography technology, affinity chromatography technology	Han KJ (2012), Han KJ (2012)	2
LNX1	7	UBE2D2	0	pull down, pull down, pull down	Nie J (2002), Nie J (2004), Guo Z (2012)	3
CUL3	17	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
UBL7	0	HDAC6	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGLN3	0	MARCH7	0	affinity chromatography technology	Rodriguez J (2016)	1
SOX2	4	RUVBL1	2	affinity chromatography technology	Engelen E (2011)	1
TDRD3	0	USP9X	15	affinity chromatography technology, pull down, pull down	Narayanan N (2017), Narayanan N (2017), Narayanan N (2017)	3
UBXN7	3	CSNK1E	0	affinity chromatography technology	Raman M (2015)	1
POU5F1	0	PEG10	2	affinity chromatography technology	Oliviero G (2015)	1
UFC1	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
MAP3K5	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBC	7	UBR4	15	affinity chromatography technology, pull down, affinity chromatography technology	Matsumoto M (2005), Nathan JA (2013), Bish RA (2007)	3
UCHL3	1	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
NANOG	0	USP34	7	affinity chromatography technology	Oliviero G (2015)	1
ERG	1	USP9X	15	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study	Wang S (2014), Wang S (2014), Wang S (2014), Wang S (2014), Wang S (2016)	5
TRIM25	5	WWC1	5	affinity chromatography technology	Choudhury NR (2017)	1
SOX2	4	AMOTL2	5	affinity chromatography technology	Cox JL (2013)	1
PRICKLE1	0	USP9X	15	affinity chromatography technology	Paemka L (2015)	1
CRY2	2	CCT4	2	affinity chromatography technology	Papp SJ (2015)	1
UBXN1	0	UFM1	0	biochemical	Havugimana PC (2012)	1
UNK	3	HUWE1	22	affinity chromatography technology	Murn J (2015)	1
ECT2	2	CAND1	2	affinity chromatography technology	Woods NT (2012)	1
CUL3	17	GEMIN5	1	affinity chromatography technology	Bennett EJ (2010)	1
USP9X	15	AMOTL2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim M (2016), Kim M (2016), Toloczko A (2017), Zhu C (2018)	4
CCDC8	1	USP9X	15	affinity chromatography technology	Hanson D (2014)	1
NTRK1	1	XPO1	8	affinity chromatography technology	Emdal KB (2015)	1
SEC23A	3	UBE2V2	0	biochemical	Havugimana PC (2012)	1
CUL3	17	EFTUD2	12	affinity chromatography technology	Bennett EJ (2010)	1
SSSCA1	0	USP9X	15	biochemical	Havugimana PC (2012)	1
HDAC5	4	DDX20	4	affinity chromatography technology	Greco TM (2011)	1
MAGED1	0	SIRT7	1	two hybrid	Stelzl U (2005)	1
XPO1	8	AMOTL2	5	affinity chromatography technology	Kirli K (2015)	1
MARK4	6	RPTOR	4	enzymatic study	Li L (2013)	1
SOX2	4	USP34	7	affinity chromatography technology	Cox JL (2013)	1
LATS2	1	ZYX	2	affinity chromatography technology, affinity chromatography technology	Ma B (2016), Ma B (2016)	2
AURKA	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
SMAD4	9	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dupont S (2009), Wu Y (2017), Wu Y (2017)	3
DPPA4	0	MCM2	3	affinity chromatography technology	Oliviero G (2015)	1
NTRK1	1	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Qian X (1998), Borrello MG (1994), Nakamura T (2002), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	7
SMURF1	4	UBXN7	3	enzymatic study	Andrews PS (2010)	1
EGFR	5	DDX20	4	affinity chromatography technology	Foerster S (2013)	1
CCDC8	1	AMOT	6	affinity chromatography technology	Hanson D (2014)	1
UBC	7	UBE2B	3	affinity chromatography technology, affinity chromatography technology	Bish RA (2007), Hong JH (2015)	2
UCHL3	1	YAP1	0	biochemical	Havugimana PC (2012)	1
DDX20	4	GEMIN2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mourelatos Z (2002), Charroux B (1999), Charroux B (1999), Piazzon N (2012), Piazzon N (2012), Huttlin EL (2017)	6
HECW2	13	TRIM25	5	affinity chromatography technology	Lu L (2013)	1
MCM2	3	HDAC6	0	affinity chromatography technology	Drissi R (2015)	1
SSSCA1	0	UBE4B	5	biochemical	Havugimana PC (2012)	1
POU5F1	0	USP9X	15	affinity chromatography technology	Oliviero G (2015)	1
CCDC8	1	AFDN	10	affinity chromatography technology	Hanson D (2014)	1
YAP1	0	EGFR	5	affinity chromatography technology	Komuro A (2003)	1
EGFR	5	GEMIN4	2	affinity chromatography technology	Foerster S (2013)	1
EFTUD2	12	USP9X	15	biochemical	Havugimana PC (2012)	1
EGLN3	0	PJA1	1	affinity chromatography technology	Rodriguez J (2016)	1
UBE2D1	0	USP34	7	biochemical	Havugimana PC (2012)	1
DPPA4	0	HUWE1	22	affinity chromatography technology	Oliviero G (2015)	1
POU5F1	0	DPPA4	0	affinity chromatography technology	Oliviero G (2015)	1
USP9X	15	PRPF8	14	biochemical	Wan C (2015)	1
MARCH7	0	UBC	7	enzymatic study	Flierman D (2006)	1
AHCYL1	2	UCHL3	1	biochemical	Havugimana PC (2012)	1
CLK3	0	ZNF263	2	two hybrid	Rolland T (2014)	1
USP34	7	UBQLN2	0	biochemical	Havugimana PC (2012)	1
HEXIM2	0	USP9X	15	affinity chromatography technology	Huttlin EL (2017)	1
ZNF598	6	TCP1	0	affinity chromatography technology	Garzia A (2017)	1
SSSCA1	0	UBE2B	3	biochemical	Havugimana PC (2012)	1
NTRK1	1	MCM2	3	affinity chromatography technology	Emdal KB (2015)	1
IQCB1	3	PSMB4	2	affinity chromatography technology	Sang L (2011)	1
CCDC8	1	XPO1	8	affinity chromatography technology	Hanson D (2014)	1
HDAC6	0	GEMIN5	1	affinity chromatography technology	Hein MY (2015)	1
USP9X	15	RPTOR	4	affinity chromatography technology	Agrawal P (2012)	1
SSSCA1	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
CCDC8	1	PRPF8	14	affinity chromatography technology	Hanson D (2014)	1
ZNHIT2	0	SNRNP200	15	bioid, affinity chromatography technology	Cloutier P (2017), Cloutier P (2017)	2
CRY2	2	EFTUD2	12	affinity chromatography technology	Papp SJ (2015)	1
UBXN7	3	UBR4	15	affinity chromatography technology	Alexandru G (2008)	1
YAP1	0	SNRPB	0	affinity chromatography technology	Enzo E (2015)	1
CTNNB1	30	SMURF1	4	affinity chromatography technology, pull down	Boonanantanasarn K (2015), Boonanantanasarn K (2015)	2
TRIM25	5	DCAF6	0	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	UBXN7	3	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	AMOT	6	affinity chromatography technology	Matsumoto M (2005)	1
CRY1	0	EFTUD2	12	affinity chromatography technology	Papp SJ (2015)	1
SNRPB	0	SNRNP200	15	affinity chromatography technology, biochemical	Ewing RM (2007), Havugimana PC (2012)	2
NTRK1	1	CCT4	2	affinity chromatography technology	Emdal KB (2015)	1
UBE2C	1	UBXN7	3	biochemical	Havugimana PC (2012)	1
XPO1	8	CRY1	0	affinity chromatography technology, affinity chromatography technology	Kirli K (2015), Papp SJ (2015)	2
UBE2D1	0	TRIM25	5	two hybrid, pull down, pull down, pull down, pull down	Markson G (2009), Gack MU (2007), Wang Y (2014), Ronchi VP (2012), Wang S (2016)	5
EGFR	5	HECW2	13	affinity chromatography technology	Yao Z (2017)	1
UBL7	0	USP9X	15	biochemical	Havugimana PC (2012)	1
XPO1	8	MARCH7	0	affinity chromatography technology	Kirli K (2015)	1
SEC24C	2	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
EGLN3	0	GEMIN4	2	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	HUWE1	22	affinity chromatography technology	Tong J (2014)	1
CFTR	5	UBXN1	0	affinity chromatography technology	Pankow S (2015)	1
NTRK1	1	SNRNP200	15	affinity chromatography technology	Emdal KB (2015)	1
UBQLN2	0	UBQLN1	1	two hybrid, affinity chromatography technology	Ford DL (2006), Ford DL (2006)	2
LNX1	7	USP9X	15	affinity chromatography technology	Lenihan JA (2017)	1
EGFR	5	NUBP2	0	affinity chromatography technology	Tong J (2014)	1
PRPF8	14	UBC	7	pull down	Song EJ (2010)	1
BIRC5	1	XPO1	8	pull down, affinity chromatography technology	Knauer SK (2006), Knauer SK (2006)	2
KIAA0368	0	USP9X	15	affinity chromatography technology	Hein MY (2015)	1
UBE2D1	0	UNK	3	biochemical	Havugimana PC (2012)	1
TRIM25	5	NUBP2	0	affinity chromatography technology	Choudhury NR (2017)	1
ZNF746	0	TRIM25	5	affinity chromatography technology	Kang H (2015)	1
CFTR	5	SEC23A	3	affinity chromatography technology	Pankow S (2015)	1
SSSCA1	0	TTLL12	3	biochemical	Havugimana PC (2012)	1
UBE4B	5	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
CRY2	2	SNRNP200	15	affinity chromatography technology	Papp SJ (2015)	1
CDH1	4	TES	1	bioid	Guo Z (2014)	1
CCDC8	1	UBC	7	affinity chromatography technology	Hanson D (2014)	1
IGBP1	1	UBE2D1	0	biochemical	Havugimana PC (2012)	1
NTRK1	1	UBQLN1	1	affinity chromatography technology	Emdal KB (2015)	1
CUL3	17	RUVBL1	2	affinity chromatography technology	Bennett EJ (2010)	1
SSSCA1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
CRY2	2	HUWE1	22	affinity chromatography technology	Papp SJ (2015)	1
XPO1	8	SMAD1	0	affinity chromatography technology	Kirli K (2015)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
MALT1	1	USP9X	15	affinity chromatography technology	Park Y (2013)	1
UBL7	0	UBQLN1	1	biochemical	Havugimana PC (2012)	1
EGLN3	0	USP34	7	affinity chromatography technology	Rodriguez J (2016)	1
USP9X	15	RICTOR	4	affinity chromatography technology	Agrawal P (2012)	1
EGLN3	0	OTUD4	2	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	SNRPB	0	affinity chromatography technology	Bennett EJ (2010)	1
SSSCA1	0	UBL7	0	biochemical	Havugimana PC (2012)	1
EGLN3	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	CCT4	2	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	CTNNB1	30	affinity chromatography technology	Emdal KB (2015)	1
CUL3	17	CCT4	2	affinity chromatography technology	Bennett EJ (2010)	1
USP9X	15	AMOT	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Thanh Nguyen H (2016), Thanh Nguyen H (2016), Toloczko A (2017)	3
XPO1	8	CTNNB1	30	affinity chromatography technology	Kirli K (2015)	1
YAP1	0	CTNNB1	30	affinity chromatography technology	Boldt K (2016)	1
BIRC2	1	USP9X	15	affinity chromatography technology	Goncharov T (2013)	1
EGLN3	0	PCGF1	1	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	BIRC2	1	affinity chromatography technology	Fu J (2016)	1
PCGF1	1	USP9X	15	affinity chromatography technology	Oliviero G (2015)	1
BIRC3	1	UBE2D2	0	x-ray crystallography, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down	Mace PD (2008), Mace PD (2008), Dynek JN (2010), Feltham R (2011), Dou H (2012), Li X (2002), Schumacher FR (2013), Choi JS (2014), Wu CJ (2006), Fang S (2001), Hu S (2003), Suzuki S (2017)	12
IGBP1	1	NUBP2	0	biochemical	Havugimana PC (2012)	1
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
LATS2	1	AMOTL1	3	affinity chromatography technology, bioid	Couzens AL (2013), Couzens AL (2013)	2
ZNHIT2	0	USP9X	15	affinity chromatography technology	Cloutier P (2017)	1
TTLL12	3	UBXN7	3	biochemical	Havugimana PC (2012)	1
CUL3	17	SNRNP200	15	affinity chromatography technology	Bennett EJ (2010)	1
AMOT	6	AMOTL1	3	affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Sowa ME (2009), Couzens AL (2013), Couzens AL (2013), Hauri S (2013)	4
SIRT7	1	KIAA0368	0	affinity chromatography technology	Tsai YC (2012)	1
CRY2	2	DDX20	4	affinity chromatography technology	Papp SJ (2015)	1
UBE2D1	0	UBE4B	5	biochemical	Havugimana PC (2012)	1
HDAC5	4	SUV39H1	0	affinity chromatography technology	Zhang CL (2002)	1
UBE2C	1	UBXN1	0	biochemical	Havugimana PC (2012)	1
LATS2	1	AFDN	10	affinity chromatography technology	Couzens AL (2013)	1
SEC24C	2	SEC23A	3	affinity chromatography technology, two hybrid, biochemical, biochemical	Pagano A (1999), Pagano A (1999), Havugimana PC (2012), Wan C (2015)	4
SRXN1	0	UNK	3	biochemical	Havugimana PC (2012)	1
SAV1	0	AMOT	6	bioid	Couzens AL (2013)	1
POU5F1	0	TCP1	0	affinity chromatography technology	Oliviero G (2015)	1
LATS2	1	CTNNB1	30	bioid, affinity chromatography technology, affinity chromatography technology, pull down	Couzens AL (2013), Li J (2013), Li J (2013), Li J (2013)	4
NTRK1	1	CUL3	17	affinity chromatography technology	Emdal KB (2015)	1
CCT4	2	KIAA0368	0	biochemical	Wan C (2015)	1
EGLN3	0	UBXN1	0	affinity chromatography technology	Rodriguez J (2016)	1
CRY2	2	GEMIN5	1	affinity chromatography technology	Papp SJ (2015)	1
LNX1	7	ELP1	5	affinity chromatography technology	Lenihan JA (2017)	1
HUWE1	22	EFTUD2	12	affinity chromatography technology	Thompson JW (2014)	1
EGLN3	0	AURKA	1	affinity chromatography technology	Rodriguez J (2016)	1
AHCYL1	2	UBA52	0	biochemical	Havugimana PC (2012)	1
TRIM25	5	AFDN	10	affinity chromatography technology	Choudhury NR (2017)	1
SMAD3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Charbonney E (2011), Zhou B (2012)	4
NANOG	0	HUWE1	22	affinity chromatography technology	Oliviero G (2015)	1
HDAC6	0	CFTR	5	affinity chromatography technology, affinity chromatography technology	Kawaguchi Y (2003), Ouyang H (2012)	2
ZNF598	6	OTUD4	2	affinity chromatography technology	Garzia A (2017)	1
KIAA0368	0	UBR4	15	biochemical	Kristensen AR (2012)	1
HUWE1	22	MCM2	3	affinity chromatography technology	Thompson JW (2014)	1
ZNF598	6	UBE2L3	1	affinity chromatography technology	Garzia A (2017)	1
EGLN3	0	USP9X	15	affinity chromatography technology	Rodriguez J (2016)	1
PSMB8	0	USP9X	15	biochemical	Havugimana PC (2012)	1
SOD1	0	MCM2	3	affinity chromatography technology	Malty RH (2017)	1
SEC23A	3	UBE2B	3	biochemical	Havugimana PC (2012)	1
MCM2	3	UBE2D2	0	affinity chromatography technology	Drissi R (2015)	1
AMOTL1	3	USP9X	15	affinity chromatography technology	Toloczko A (2017)	1
SMAD2	5	SMURF1	4	affinity chromatography technology, affinity chromatography technology, two hybrid	Komuro A (2004), Ito I (2010), Colland F (2004)	3
ITCH	1	UBC	7	enzymatic study, unspecified method, enzymatic study, enzymatic study	Sheng Y (2012), Ernst A (2013), Maspero E (2013), Kristariyanto YA (2015)	4
USP9X	15	YAP1	0	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kim M (2016), Kim M (2016)	3
LATS2	1	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Toloczko A (2017), Toloczko A (2017), Toloczko A (2017), Zhu C (2018), Zhu C (2018), Zhu C (2018)	7
USP9X	15	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
CCT4	2	XPO1	8	biochemical	Havugimana PC (2012)	1
UBE2L3	1	UBE2B	3	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SMAD1	0	SMAD4	9	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Hanai J (1999), Lopez-Rovira T (2002), Kato Y (2002), Wang L (2011), Li L (2004), Hata A (1998), Barrios-Rodiles M (2005), Wu RY (1997), Wu RY (1997), Colland F (2004), Qiu T (2007), Yan X (2016), Zhou F (2017)	14
NTRK1	1	AFDN	10	affinity chromatography technology	Emdal KB (2015)	1
SMURF1	4	SNRPB	0	affinity chromatography technology	Xie Y (2013)	1
UBA52	0	UNK	3	biochemical	Havugimana PC (2012)	1
BIRC2	1	UBE2D2	0	two hybrid, pull down, pull down, pull down	Dynek JN (2010), Li X (2002), Feltham R (2011), Choi YE (2009)	4
AHCYL1	2	YAP1	0	biochemical	Havugimana PC (2012)	1
TRIM25	5	MTOR	14	affinity chromatography technology	Choudhury NR (2017)	1
ZNHIT2	0	EFTUD2	12	bioid, affinity chromatography technology	Cloutier P (2017), Cloutier P (2017)	2
ITCH	1	DDX20	4	affinity chromatography technology	Han KJ (2016)	1
CAND1	2	ZYX	2	biochemical	Kristensen AR (2012)	1
CAND1	2	RUVBL1	2	affinity chromatography technology	Bennett EJ (2010)	1
UBQLN2	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
USP9X	15	GEMIN8	1	affinity chromatography technology	Han KJ (2012)	1
UBE4B	5	USP34	7	biochemical	Havugimana PC (2012)	1
TRIM25	5	HUWE1	22	affinity chromatography technology	Choudhury NR (2017)	1
SSSCA1	0	ZYX	2	biochemical	Havugimana PC (2012)	1
VHL	0	CCT4	2	affinity chromatography technology	Lai Y (2011)	1
CUL3	17	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Bish RA (2007), Wu K (2016)	4
UBE4B	5	UBXN7	3	biochemical	Havugimana PC (2012)	1
WWP2	7	UBE2L3	1	pull down, pull down, pull down, pull down, pull down, pull down	Wiesner S (2007), Xu H (2009), Anindya R (2007), Kristariyanto YA (2015), Zhang W (2016), Chen Z (2016)	6
UBXN7	3	YAP1	0	biochemical	Havugimana PC (2012)	1
BIRC2	1	UBC	7	pull down, pull down, pull down, pull down, enzymatic study	Dynek JN (2010), Gyrd-Hansen M (2008), Gyrd-Hansen M (2008), Komander D (2009), Sakamoto H (2015)	5
MIB1	5	GEMIN4	2	affinity chromatography technology	Wang J (2013)	1
AHCYL1	2	UBE2C	1	biochemical	Havugimana PC (2012)	1
AHCYL1	2	UBE2D1	0	biochemical	Havugimana PC (2012)	1
UBE2C	1	UNK	3	biochemical	Havugimana PC (2012)	1
UBC	7	NFX1	2	pull down	Zhang X (2017)	1
WWP2	7	USP9X	15	affinity chromatography technology	Chaudhary N (2014)	1
CUL3	17	PRPF8	14	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	UBE2L3	1	biochemical	Havugimana PC (2012)	1
CUL3	17	AMOT	6	affinity chromatography technology	Bennett EJ (2010)	1
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
UBE2D1	0	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
POU5F1	0	KIAA0368	0	affinity chromatography technology	Oliviero G (2015)	1
UBE2B	3	UBXN7	3	biochemical	Havugimana PC (2012)	1
TRIM25	5	UBE2L3	1	affinity chromatography technology	Choudhury NR (2017)	1
SAV1	0	LATS2	1	bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Rashidian J (2015), Bae SJ (2015)	3
PSMA4	0	USP9X	15	biochemical	Havugimana PC (2012)	1
UBL7	0	UBC	7	x-ray crystallography, pull down, pull down	Chang YG (2006), Fenner BJ (2009), Zhang X (2017)	3
IGBP1	1	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
IQCB1	3	PSMA4	0	affinity chromatography technology	Sang L (2011)	1
SRXN1	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
UBE2C	1	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
TERF1	1	CLK3	0	affinity chromatography technology	Giannone RJ (2010)	1
ZNF746	0	IRS4	2	affinity chromatography technology	Kang H (2015)	1
TRIM25	5	SMAD3	1	affinity chromatography technology	Choudhury NR (2017)	1
UFC1	0	UFM1	0	affinity chromatography technology, biochemical, pull down, biochemical	Komatsu M (2004), Havugimana PC (2012), Gavin JM (2014), Wan C (2015)	4
SNRPB	0	EFTUD2	12	affinity chromatography technology	Ewing RM (2007)	1
CTNNB1	30	POU5F1	0	affinity chromatography technology, affinity chromatography technology	Xu C (2013), Xu C (2013)	2
UBQLN1	1	USP9X	15	biochemical	Havugimana PC (2012)	1
ARL6IP5	0	USP9X	15	biochemical	Havugimana PC (2012)	1
IGBP1	1	YAP1	0	biochemical	Havugimana PC (2012)	1
UBQLN2	0	USP9X	15	biochemical	Havugimana PC (2012)	1
SIRT7	1	MTOR	14	affinity chromatography technology	Tsai YC (2012)	1
SOD1	0	RUVBL1	2	affinity chromatography technology	Malty RH (2017)	1
PTPN14	5	HECW2	13	affinity chromatography technology	Li X (2016)	1
VHL	0	UBE2D2	0	pull down	Xin H (2011)	1
UFM1	0	YAP1	0	biochemical	Havugimana PC (2012)	1
TRIM25	5	RPTOR	4	affinity chromatography technology	Choudhury NR (2017)	1
PTPDC1	3	USP9X	15	affinity chromatography technology	St-Denis N (2016)	1
DCAF6	0	USP9X	15	biochemical	Kristensen AR (2012)	1
HDAC5	4	CCT4	2	affinity chromatography technology	Greco TM (2011)	1
ITCH	1	UBE2D2	0	pull down, pull down, pull down, pull down	Sheng Y (2012), Fang S (2001), Kristariyanto YA (2015), Riling C (2015)	4
UNK	3	YAP1	0	biochemical	Havugimana PC (2012)	1
NANOG	0	PEG10	2	affinity chromatography technology	Oliviero G (2015)	1
NTRK1	1	GEMIN5	1	affinity chromatography technology	Emdal KB (2015)	1
SMAD1	0	PSMB4	2	affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid	Lin Y (2002), Lin Y (2002), Guo X (2001), Gruendler C (2001), Colland F (2004)	5
IQCB1	3	GEMIN2	1	affinity chromatography technology	Sang L (2011)	1
SAV1	0	HDAC6	0	bioid	Couzens AL (2013)	1
UBE2B	3	UBQLN1	1	biochemical	Havugimana PC (2012)	1
ERG	1	PRPF8	14	affinity chromatography technology, affinity chromatography technology, pull down	Brenner JC (2011), Wang S (2014), Wang S (2014)	3
CDH1	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Davies G (2001), Kucerova D (2001), Oyama T (1994), Hazan RB (1997), Kinch MS (1995), Jiang MC (2002), Hazan RB (1998), Bonvini P (2001), Li Y (1998), Wendeler MW (2004), Shibata T (2003), Piedra J (2003), Oneyama C (2002), Navarro P (1993), Takahashi K (1997), Dobrosotskaya IY (2000), Dobrosotskaya IY (2000), Geng L (2000), Shibamoto S (1995), Rao RK (2002), Rao RK (2002), Huber AH (2001), Schmeiser K (1999), Pai R (2008), Tu LC (2007), Tu LC (2007), Smyth D (2012), Xue B (2005), Xue B (2005), Catimel B (2005), Huang Z (2012), Yan HX (2006), Yan HX (2006), Figueiredo J (2013), Ponce E (2014), Ponce E (2014), Ponce E (2014), Ribeiro AS (2013), Pinheiro H (2012), Geng F (2012), Lee HK (2007), Guo Z (2014)	42
PTPN21	10	AMOT	6	affinity chromatography technology	Li X (2016)	1
CCDC8	1	ELP1	5	affinity chromatography technology	Hanson D (2014)	1
CRY1	0	USP9X	15	affinity chromatography technology	Papp SJ (2015)	1
ERG	1	HUWE1	22	pull down	Wang S (2016)	1
SMAD1	0	UCHL3	1	affinity chromatography technology, affinity chromatography technology	Kim JY (2011), Kim JY (2011)	2
WWP2	7	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soond SM (2011), Soond SM (2011), Brown KA (2008)	3
PCGF1	1	NANOG	0	biochemical, affinity chromatography technology	Oliviero G (2015), Oliviero G (2015)	2
GRK5	7	HDAC6	0	affinity chromatography technology	Wu Z (2012)	1
SUPV3L1	2	USP9X	15	affinity chromatography technology	Huttlin EL (2017)	1
VHL	0	AURKA	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Martin B (2013), Martin B (2013), Hasanov E (2017), Hasanov E (2017), Hasanov E (2017)	5
NUAK1	2	LATS1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Humbert N (2010), Humbert N (2010), Humbert N (2010)	3
EGFR	5	TCP1	0	affinity chromatography technology	Yao Z (2017)	1
UCHL3	1	UNK	3	biochemical	Havugimana PC (2012)	1
HUWE1	22	SNRPB	0	affinity chromatography technology	Thompson JW (2014)	1
BIRC2	1	BCL10	0	affinity chromatography technology, affinity chromatography technology	Yoneda T (2000), Hu S (2006)	2
NUDCD2	2	USP9X	15	biochemical	Havugimana PC (2012)	1
MAGED1	0	PJA1	1	two hybrid, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down	Sasaki A (2002), Sasaki A (2002), Sasaki A (2002), Sasaki A (2002), Doyle JM (2010), Doyle JM (2010)	6
SOD1	0	HUWE1	22	affinity chromatography technology	Malty RH (2017)	1
HDAC6	0	BIRC5	1	affinity chromatography technology	Riolo MT (2012)	1
IGBP1	1	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
TERF1	1	IRS4	2	affinity chromatography technology	Giannone RJ (2010)	1
WWP2	7	UBE2D2	0	pull down, pull down, pull down	Sheng Y (2012), Kristariyanto YA (2015), Chaudhary N (2014)	3
TRIM25	5	DDX20	4	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
NTRK1	1	GEMIN4	2	affinity chromatography technology	Emdal KB (2015)	1
SHC1	0	RUVBL1	2	affinity chromatography technology	Brehme M (2009)	1
TRIM25	5	BIRC2	1	affinity chromatography technology	Choudhury NR (2017)	1
HUWE1	22	PRPF8	14	biochemical	Havugimana PC (2012)	1
UBE2D1	0	UBC	7	x-ray crystallography	Bosanac I (2010)	1
SHC1	0	USP9X	15	affinity chromatography technology	Brehme M (2009)	1
USP9X	15	PJA1	1	affinity chromatography technology	Agrawal P (2012)	1
UBXN1	0	UBR4	15	affinity chromatography technology	Alexandru G (2008)	1
XPO1	8	BCL10	0	affinity chromatography technology	Kirli K (2015)	1
SMAD3	1	HDAC5	4	affinity chromatography technology, pull down	Kang JS (2005), Kang JS (2005)	2
GRK5	7	SNCA	0	enzymatic study	Pronin AN (2000)	1
CUL3	17	CTNNB1	30	affinity chromatography technology	Bennett EJ (2010)	1
EGFR	5	PRICKLE1	0	affinity chromatography technology	Yao Z (2017)	1
UCHL3	1	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
SSSCA1	0	TES	1	biochemical	Havugimana PC (2012)	1
XPO1	8	YAP1	0	affinity chromatography technology	Kirli K (2015)	1
ZNF263	2	NFX1	2	affinity chromatography technology	Huttlin EL (2017)	1
PTPN14	5	UBC	7	affinity chromatography technology	Wang W (2012)	1
USP9X	15	UBC	7	unspecified method, pull down	Ernst A (2013), Kwasna D (2018)	2
SMURF1	4	PSMA4	0	affinity chromatography technology	Xie Y (2013)	1
UBE4B	5	USP9X	15	biochemical	Havugimana PC (2012)	1
ZYX	2	VHL	0	affinity chromatography technology	Foxler DE (2012)	1
USP9X	15	MAGED1	0	affinity chromatography technology	Agrawal P (2012)	1
PJA1	1	UCHL3	1	enzymatic study	Loch CM (2012)	1
HUWE1	22	RUVBL1	2	affinity chromatography technology	Thompson JW (2014)	1
MTOR	14	USP9X	15	affinity chromatography technology, affinity chromatography technology	Agrawal P (2012), Agrawal P (2012)	2
UBXN1	0	UBE4B	5	affinity chromatography technology	Alexandru G (2008)	1
SIRT7	1	SEC24C	2	affinity chromatography technology	Tsai YC (2012)	1
UBXN1	0	MARCH7	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
YAP1	0	ITCH	1	affinity chromatography technology	Levy D (2007)	1
SAV1	0	LATS1	3	affinity chromatography technology	Guo C (2007)	1
CDH1	4	AFDN	10	bioid	Guo Z (2014)	1
CLK3	0	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
EGLN3	0	CAND1	2	affinity chromatography technology	Rodriguez J (2016)	1
BIRC3	1	UBR4	15	affinity chromatography technology	Goncharov T (2013)	1
GEMIN2	1	GEMIN4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Piazzon N (2012), Piazzon N (2012), Huttlin EL (2017), Horlbeck MA (2018)	4
ZNF598	6	CAND1	2	affinity chromatography technology	Garzia A (2017)	1
CAND1	2	SNRPB	0	affinity chromatography technology	Bennett EJ (2010)	1
ZNF598	6	PSMB4	2	affinity chromatography technology	Garzia A (2017)	1
MCM2	3	USP9X	15	affinity chromatography technology	Drissi R (2015)	1
SIRT7	1	TTLL12	3	affinity chromatography technology	Tsai YC (2012)	1
XPO1	8	PTPDC1	3	affinity chromatography technology	Kirli K (2015)	1
IRS4	2	EGFR	5	unspecified method, affinity chromatography technology	Jones RB (2006), Tong J (2014)	2
NTRK1	1	DDX20	4	affinity chromatography technology	Emdal KB (2015)	1
HECW2	13	AMOTL1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lu L (2013), Choi KS (2016), Choi KS (2016)	3
PTPN14	5	AMOT	6	affinity chromatography technology, affinity chromatography technology	Wang W (2012), Li X (2016)	2
DPPA4	0	USP34	7	affinity chromatography technology	Oliviero G (2015)	1
CFTR	5	MCM2	3	affinity chromatography technology	Pankow S (2015)	1
SMAD3	1	SMURF1	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Colland F (2004), Li Y (2017), Li Y (2017)	4
SNRPB	0	GEMIN4	2	affinity chromatography technology	Ewing RM (2007)	1
UBXN7	3	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	4
ITCH	1	UBE2L3	1	pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down	Wiesner S (2007), Ishihara T (2011), Scialpi F (2008), Bai Y (2004), Oberst A (2007), Mouchantaf R (2006), Rossi M (2005), Zhang P (2010), Anindya R (2007), Kathania M (2015), Kristariyanto YA (2015), Riling C (2015), Riling C (2015), Zhang W (2016)	14
EGFR	5	KIAA0368	0	affinity chromatography technology	Tong J (2014)	1
UBXN7	3	ZYX	2	biochemical	Havugimana PC (2012)	1
TRIM25	5	XPO1	8	affinity chromatography technology	Choudhury NR (2017)	1
VHL	0	UBC	7	pull down	Lisztwan J (1999)	1
MCM2	3	UBE2L3	1	affinity chromatography technology	Drissi R (2015)	1
XPO1	8	IQCB1	3	affinity chromatography technology	Kirli K (2015)	1
CDH1	4	YAP1	0	bioid	Guo Z (2014)	1
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
SIRT7	1	XPO1	8	affinity chromatography technology	Tsai YC (2012)	1
USP34	7	UNK	3	biochemical	Havugimana PC (2012)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
CFTR	5	CTNNB1	30	affinity chromatography technology	Pankow S (2015)	1
UBXN1	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
IGBP1	1	UBQLN2	0	biochemical	Havugimana PC (2012)	1
MAP3K5	1	USP9X	15	affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study	Nagai H (2009), Nagai H (2009), Nagai H (2009), Nagai H (2009)	4
IGBP1	1	USP9X	15	biochemical	Havugimana PC (2012)	1
USP9X	15	GEMIN5	1	affinity chromatography technology	Han KJ (2012)	1
IQCB1	3	USP9X	15	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Das A (2017), Das A (2017), Das A (2017), Das A (2017)	4
SIRT7	1	USP9X	15	affinity chromatography technology	Tsai YC (2012)	1
UBE2V2	0	UFM1	0	biochemical	Havugimana PC (2012)	1
NTRK1	1	USP9X	15	affinity chromatography technology	Emdal KB (2015)	1
POU5F1	0	DDX20	4	affinity chromatography technology	Oliviero G (2015)	1
AHCYL1	2	TES	1	biochemical	Havugimana PC (2012)	1
TRIM25	5	EGLN3	0	affinity chromatography technology	Choudhury NR (2017)	1
UNK	3	CCT4	2	affinity chromatography technology	Murn J (2015)	1
LATS2	1	AMOTL2	5	affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Paramasivam M (2011), Paramasivam M (2011), Couzens AL (2013), Kim M (2016), Kim M (2016)	5
IGBP1	1	CCT4	2	affinity chromatography technology, affinity chromatography technology	Gingras AC (2005), Hein MY (2015)	2
WWP2	7	SMAD3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, two hybrid	Soond SM (2011), Soond SM (2011), Soond SM (2011), Brown KA (2008), Soond SM (2013), Yu H (2011)	6
SSSCA1	0	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
EGLN3	0	TTLL12	3	affinity chromatography technology	Rodriguez J (2016)	1
HUWE1	22	SNRNP200	15	biochemical	Havugimana PC (2012)	1
CUL3	17	ELP1	5	affinity chromatography technology	Bennett EJ (2010)	1
PEG10	2	IQCB1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	OTUD4	2	affinity chromatography technology	Kirli K (2015)	1
AHCYL1	2	USP34	7	biochemical	Havugimana PC (2012)	1
HECW2	13	USP9X	15	affinity chromatography technology	Lu L (2013)	1
CFTR	5	EGFR	5	affinity chromatography technology	Pankow S (2015)	1
EGLN3	0	TCP1	0	affinity chromatography technology	Rodriguez J (2016)	1
UBQLN1	1	MTOR	14	two hybrid, affinity chromatography technology, two hybrid	Wu S (2002), Wu S (2002), Wu S (2002)	3
USP9X	15	MAGED4	0	affinity chromatography technology	Agrawal P (2012)	1
CUL3	17	GPSM1	1	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	MAP3K5	1	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	ITCH	1	affinity chromatography technology	Bennett EJ (2010)	1
XPO1	8	AURKA	1	affinity chromatography technology	Kirli K (2015)	1
TRIM25	5	SEC23A	3	affinity chromatography technology	Choudhury NR (2017)	1
NEK6	2	USP9X	15	affinity chromatography technology	Ewing RM (2007)	1
CTNNB1	30	UBE2D1	0	pull down	Saha A (2008)	1
AMOT	6	AMOTL2	5	affinity chromatography technology, bioid	Wells CD (2006), Couzens AL (2013)	2
ZNF746	0	CAND1	2	affinity chromatography technology	Kang H (2015)	1
TTLL12	3	UBE2C	1	biochemical	Havugimana PC (2012)	1
CUL3	17	SUPV3L1	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D1	0	MIB1	5	two hybrid	van Wijk SJ (2009)	1
EGLN3	0	AMOT	6	affinity chromatography technology	Rodriguez J (2016)	1
PSMA4	0	PSMB8	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical	Nandi D (1997), Khu YL (2004), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	5
UBE2L3	1	USP9X	15	biochemical	Havugimana PC (2012)	1
UNK	3	XPO1	8	affinity chromatography technology	Murn J (2015)	1
NTRK1	1	TCP1	0	affinity chromatography technology	Emdal KB (2015)	1
LATS2	1	PTPN14	5	bioid	Couzens AL (2013)	1
UBE2V2	0	USP9X	15	biochemical	Havugimana PC (2012)	1
TTLL12	3	UNK	3	biochemical	Havugimana PC (2012)	1
HECW2	13	AMOTL2	5	affinity chromatography technology	Choi KS (2016)	1
AURKA	1	UBE2L3	1	affinity chromatography technology	Ewing RM (2007)	1
CUL3	17	MAGED1	0	affinity chromatography technology	Bennett EJ (2010)	1
RUVBL1	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bauer A (1998), Bauer A (1998), Bauer A (1998), Bauer A (1998), Sierra J (2006), Gomes NP (2006), Kim JH (2007), Kim JH (2007)	8
UBE2D2	0	USP9X	15	biochemical	Havugimana PC (2012)	1
SSSCA1	0	UCHL3	1	biochemical	Havugimana PC (2012)	1
EGLN3	0	DDX20	4	affinity chromatography technology	Rodriguez J (2016)	1
UBE2B	3	UBE2C	1	biochemical	Havugimana PC (2012)	1
SSSCA1	0	UBE2C	1	biochemical	Havugimana PC (2012)	1
AHCYL1	2	UBE2L3	1	biochemical	Havugimana PC (2012)	1
SRXN1	0	TTLL12	3	biochemical	Havugimana PC (2012)	1
BIRC2	1	BIRC3	1	affinity chromatography technology, affinity chromatography technology	Rajalingam K (2006), Rajalingam K (2006)	2
UBE2L3	1	UBE4B	5	biochemical	Havugimana PC (2012)	1
UBE2B	3	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
PRICKLE2	2	USP9X	15	affinity chromatography technology	Paemka L (2015)	1
PTPN21	10	WWC1	5	affinity chromatography technology, affinity chromatography technology	Li X (2016), Li X (2016)	2
UBE2D1	0	USP9X	15	biochemical, biochemical	Havugimana PC (2012), You J (2001)	2
USP34	7	UCHL3	1	biochemical	Havugimana PC (2012)	1
MARK4	6	USP9X	15	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Al-Hakim AK (2008), Al-Hakim AK (2008), Al-Hakim AK (2008), Brajenovic M (2004)	4
AURKA	1	USP9X	15	affinity chromatography technology	Fogeron ML (2013)	1
UNK	3	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
UBC	7	UBE2L3	1	affinity chromatography technology	Bish RA (2007)	1
UBC	7	CCT4	2	affinity chromatography technology	Bish RA (2007)	1
UFC1	0	UNK	3	biochemical	Havugimana PC (2012)	1
EGLN3	0	CTNNB1	30	affinity chromatography technology	Rodriguez J (2016)	1
TES	1	UBR4	15	affinity chromatography technology	Sala S (2017)	1
CFTR	5	ITCH	1	affinity chromatography technology	Pankow S (2015)	1
TERF1	1	HEXIM2	0	two hybrid	Lee OH (2011)	1
BIRC3	1	UBE2L3	1	affinity chromatography technology	Hu S (2003)	1
CTNNB1	30	UBE2B	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, enzymatic study	Gerard B (2012), Gerard B (2012), Gerard B (2012), Gerard B (2012), Gerard B (2012), Shekhar MP (2008)	6
USP34	7	UBXN1	0	biochemical	Havugimana PC (2012)	1
EGFR	5	UBE2V2	0	protein complementation assay	Deribe YL (2009)	1
CDH1	4	ZYX	2	bioid	Guo Z (2014)	1
TTLL12	3	USP34	7	biochemical	Havugimana PC (2012)	1
MAP3K5	1	GEMIN5	1	affinity chromatography technology, affinity chromatography technology, pull down	Kim EK (2007), Kim EK (2007), Kim EK (2007)	3
CDH1	4	IGBP1	1	bioid	Guo Z (2014)	1
UBE2D2	0	UBQLN1	1	biochemical	Havugimana PC (2012)	1
VHL	0	TCP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lai Y (2011), Grosfeld A (2007), Feldman DE (2003), Feldman DE (2003), Yang C (2013)	5
PSMB4	2	USP9X	15	biochemical	Havugimana PC (2012)	1
UBXN7	3	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
UBE2V2	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
UBE4B	5	UBQLN1	1	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
ZNF746	0	CCT4	2	affinity chromatography technology	Kang H (2015)	1
MCM2	3	UBC	7	affinity chromatography technology	Drissi R (2015)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
BIRC2	1	UBE2B	3	two hybrid	Dynek JN (2010)	1
SMAD3	1	YAP1	0	affinity chromatography technology	Alarcon C (2009)	1
TERF1	1	USP9X	15	affinity chromatography technology	Giannone RJ (2010)	1
UBE2C	1	USP9X	15	biochemical	Havugimana PC (2012)	1
CCDC8	1	PEX5	2	affinity chromatography technology	Hanson D (2014)	1
HUWE1	22	CCT4	2	affinity chromatography technology	Thompson JW (2014)	1
SOX2	4	USP9X	15	affinity chromatography technology	Cox JL (2013)	1
IGBP1	1	SRXN1	0	biochemical	Havugimana PC (2012)	1
YAP1	0	PSMB4	2	affinity chromatography technology	Enzo E (2015)	1
ZNF598	6	USP9X	15	affinity chromatography technology	Garzia A (2017)	1
SIRT7	1	SEC23A	3	affinity chromatography technology	Tsai YC (2012)	1
UBE2L3	1	UBXN7	3	biochemical	Havugimana PC (2012)	1
USP34	7	USP9X	15	biochemical	Havugimana PC (2012)	1
UBL7	0	UCHL3	1	biochemical	Havugimana PC (2012)	1
HDAC5	4	MCM2	3	affinity chromatography technology	Greco TM (2011)	1
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
ZNF746	0	TCP1	0	affinity chromatography technology	Kang H (2015)	1
GEMIN4	2	DDX20	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carnegie GK (2003), Charroux B (2000), Charroux B (2000), Mourelatos Z (2002), Joshi P (2013), Joshi P (2013), Huttlin EL (2017)	7
USP34	7	UBXN7	3	biochemical	Havugimana PC (2012)	1
MTOR	14	SMAD4	9	genetic interference	Shen JP (2017)	1
SIRT7	1	GEMIN5	1	affinity chromatography technology	Tsai YC (2012)	1
AHCYL1	2	UBXN1	0	biochemical	Havugimana PC (2012)	1
SIRT7	1	IRS4	2	affinity chromatography technology	Tsai YC (2012)	1
DPPA4	0	USP9X	15	affinity chromatography technology	Oliviero G (2015)	1
HUWE1	22	MCL1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Warr MR (2005), Warr MR (2005), Warr MR (2011), Warr MR (2011), Pandya RK (2010), Gomez-Bougie P (2011), Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010), Pervin S (2011), Bewley MA (2011), Bewley MA (2011), Rolfo A (2012), Rolfo A (2012), Stankiewicz AR (2009), Zhong Q (2005), Zhong Q (2005), Liao M (2011), Thompson JW (2014), Park SH (2016), Sander B (2017)	21
UBE2L3	1	UBE2V2	0	biochemical	Havugimana PC (2012)	1
UNK	3	TCP1	0	affinity chromatography technology	Murn J (2015)	1
SMAD2	5	SOD1	0	pull down	Miyamoto-Sato E (2010)	1
CFTR	5	HUWE1	22	affinity chromatography technology	Pankow S (2015)	1
UBE2D1	0	UFM1	0	two hybrid, biochemical	van Wijk SJ (2009), Havugimana PC (2012)	2
SNCA	0	SNRNP200	15	affinity chromatography technology	Hein MY (2015)	1
CCDC8	1	TCP1	0	affinity chromatography technology	Hanson D (2014)	1
CUL3	17	SEC23A	3	affinity chromatography technology	Bennett EJ (2010)	1
SUV39H1	0	CTNNB1	30	affinity chromatography technology	Takahashi A (2011)	1
HECW2	13	NFX1	2	affinity chromatography technology	Lu L (2013)	1
SOX2	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cox JL (2013), Xu C (2013), Xu C (2013)	3
NTRK1	1	HDAC6	0	affinity chromatography technology	Emdal KB (2015)	1
SMURF1	4	USP9X	15	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Xie Y (2013), Xie Y (2013), Xie Y (2013), Xie Y (2013)	4
CUL3	17	SMN2	0	affinity chromatography technology	Bennett EJ (2010)	1
UBXN1	0	UFC1	0	biochemical	Havugimana PC (2012)	1
XPO1	8	MALT1	1	affinity chromatography technology	Kirli K (2015)	1
ECT2	2	SNRNP200	15	two hybrid, affinity chromatography technology	Woods NT (2012), Woods NT (2012)	2
IGBP1	1	UBXN1	0	biochemical	Havugimana PC (2012)	1
XPO1	8	SEC24C	2	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	SMN2	0	affinity chromatography technology	Kirli K (2015)	1
PTPN21	10	AHCYL1	2	affinity chromatography technology	Li X (2016)	1
TERF1	1	DCX	5	two hybrid	Lee OH (2011)	1
CCDC8	1	GEMIN2	1	affinity chromatography technology	Hanson D (2014)	1
SNRPB	0	PRPF8	14	affinity chromatography technology	Ewing RM (2007)	1
ZNF598	6	PSMA4	0	affinity chromatography technology	Garzia A (2017)	1
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
MTOR	14	RICTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jacinto E (2004), Jacinto E (2004), Sarbassov DD (2004), Sarbassov DD (2004), Sarbassov DD (2004), Frias MA (2006), Jacinto E (2006), Yang Q (2006), Frias MA (2006), Sarbassov DD (2006), Sarbassov DD (2005), Yang Q (2006), Kaizuka T (2010), Pearce LR (2007), Oh WJ (2010), Oh WJ (2010), Agrawal P (2012), Guo Z (2012), Sarbassov DD (2006), Sancak Y (2007), Yang Q (2006), Jacinto E (2006), Jacinto E (2006), Rosner M (2010), Ikenoue T (2008), Ikenoue T (2008), Murata H (2011), Murata H (2011), Koike-Kumagai M (2009), Koike-Kumagai M (2009), Woods NT (2012), Hussain S (2013), Peterson TR (2009), Peterson TR (2009), Su WC (2009), Hernandez-Negrete I (2007), Ramirez-Rangel I (2011), Martin J (2008), Martin J (2008), Martin J (2008), Thedieck K (2007), Thedieck K (2007), Thedieck K (2007), McDonald PC (2008), McDonald PC (2008), Hong F (2008), Hong F (2008), Facchinetti V (2008), Toschi A (2009), Zhang F (2010), Chen CH (2011), Chen CH (2011), Xu Y (2013), Xu Y (2013), Glidden EJ (2012), Glidden EJ (2012), Vander Haar E (2007), Koo J (2015), Thedieck K (2007)	59
XPO1	8	SHC1	0	affinity chromatography technology	Kirli K (2015)	1
USP9X	15	CDH1	4	biochemical	Murray RZ (2004)	1
UBXN1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008)	2
LATS1	3	SMURF1	4	unspecified method	Salah Z (2013)	1
ZNF263	2	USP9X	15	affinity chromatography technology	Huttlin EL (2017)	1
SIRT7	1	GEMIN4	2	affinity chromatography technology	Tsai YC (2012)	1
PSD4	5	USP9X	15	affinity chromatography technology, pull down, pull down	Theard D (2010), Theard D (2010), Theard D (2010)	3
CRY2	2	USP9X	15	affinity chromatography technology	Papp SJ (2015)	1
UBC	7	UBQLN1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid, pull down, two hybrid, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Matsumoto M (2005), Ko HS (2004), Ko HS (2004), Sokratous K (2012), Raasi S (2005), Raasi S (2005), Massey LK (2004), Ko HS (2004), Ko HS (2004), Rolland T (2014), Castaneda CA (2013), Nakayasu ES (2013), Nakayasu ES (2013), Kristariyanto YA (2015), Kristariyanto YA (2015), Kurlawala Z (2017)	16
HUWE1	22	UBE2D2	0	pull down, pull down, pull down, pull down	Warr MR (2005), Kristariyanto YA (2015), Li L (2015), Zhang W (2016)	4
NTRK1	1	PRPF8	14	affinity chromatography technology	Emdal KB (2015)	1
PRPF8	14	EFTUD2	12	far western blotting, pull down, two hybrid, two hybrid, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology	Achsel T (1998), Achsel T (1998), Liu S (2006), Liu S (2006), Havugimana PC (2012), Pena V (2007), Guo R (2014), Wan C (2015), Boldt K (2016)	9
MCM2	3	UBXN1	0	affinity chromatography technology	Drissi R (2015)	1
SMAD2	5	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Xi Y (2013)	3
SSSCA1	0	UBQLN2	0	biochemical	Havugimana PC (2012)	1
SRXN1	0	USP9X	15	biochemical	Havugimana PC (2012)	1
GRK5	7	RUVBL1	2	affinity chromatography technology	Wu Z (2012)	1
AHCYL1	2	UFM1	0	biochemical	Havugimana PC (2012)	1
SNCA	0	UBC	7	fluorescent resonance energy transfe, affinity chromatography technology	Sharma N (2001), Nemes Z (2009)	2
SMAD4	9	CTNNB1	30	affinity chromatography technology	Tian YC (2002)	1
ZNF746	0	USP9X	15	affinity chromatography technology	Kang H (2015)	1
ITCH	1	POU5F1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Liao B (2012), Liao B (2012), Liao B (2012), Liao B (2010)	4
ZNF746	0	EFTUD2	12	affinity chromatography technology	Kang H (2015)	1
WWP2	7	UBE2D1	0	pull down, pull down	Kristariyanto YA (2015), Chen Z (2016)	2
UBE2L3	1	UFM1	0	biochemical	Wan C (2015)	1
UBXN7	3	UFM1	0	biochemical	Havugimana PC (2012)	1
LNX1	7	ALKBH3	1	two hybrid	Rolland T (2014)	1
VHL	0	UBE2D1	0	pull down	Gao C (2010)	1
ZNF408	0	USP9X	15	affinity chromatography technology	Huttlin EL (2017)	1
RPS6KB2	3	MAGED1	0	affinity chromatography technology	Roy R (2014)	1
AHCYL1	2	UBE2D2	0	biochemical	Havugimana PC (2012)	1
HUWE1	22	XPO1	8	affinity chromatography technology	Thompson JW (2014)	1
CUL3	17	UBE2D1	0	pull down	Sumara I (2007)	1
NUBP2	0	YAP1	0	biochemical	Havugimana PC (2012)	1
MCM2	3	XPO1	8	affinity chromatography technology	Drissi R (2015)	1
UBE2C	1	UBE4B	5	biochemical	Havugimana PC (2012)	1
VHL	0	HUWE1	22	affinity chromatography technology	Zhang C (2016)	1
ITCH	1	HDAC6	0	affinity chromatography technology	OConnor HF (2015)	1
NTRK1	1	PSMA4	0	affinity chromatography technology	Emdal KB (2015)	1
EGLN3	0	GEMIN2	1	affinity chromatography technology	Rodriguez J (2016)	1
UBL7	0	USP34	7	biochemical	Havugimana PC (2012)	1
CDH1	4	UBC	7	bioid	Guo Z (2014)	1
UBE2L3	1	UCHL3	1	biochemical	Havugimana PC (2012)	1
SRXN1	0	USP34	7	biochemical	Havugimana PC (2012)	1
SSSCA1	0	UFC1	0	biochemical	Havugimana PC (2012)	1
AURKA	1	ZNF598	6	genetic interference	Horlbeck MA (2018)	1
ERG	1	TRIM25	5	pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang S (2016), Wang S (2016), Wang S (2016), Wang S (2016), Wang S (2016)	5
MCM2	3	UBR4	15	affinity chromatography technology	Drissi R (2015)	1
UBQLN1	1	UCHL3	1	biochemical	Havugimana PC (2012)	1
UBXN7	3	VHL	0	affinity chromatography technology	Alexandru G (2008)	1
SEC23A	3	TTLL12	3	biochemical	Havugimana PC (2012)	1
EGLN3	0	CCDC8	1	affinity chromatography technology	Rodriguez J (2016)	1
CCDC8	1	EFTUD2	12	affinity chromatography technology	Hanson D (2014)	1
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
BIRC2	1	BIRC5	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Dohi T (2004), Samuel T (2005), Samuel T (2005), Jung SA (2015), Jung SA (2015), Jung SA (2015)	6
CRY1	0	TCP1	0	affinity chromatography technology	Papp SJ (2015)	1
HECW2	13	UBE2L3	1	pull down, pull down	Miyazaki K (2003), Zhang W (2016)	2
LATS1	3	ITCH	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, unspecified method	Salah Z (2011), Salah Z (2011), Salah Z (2011), Ho KC (2011), Adler JJ (2013), Ho KC (2011), Ho KC (2011), Ho KC (2011), Salah Z (2013)	9
TTLL12	3	ZYX	2	biochemical	Havugimana PC (2012)	1
BIRC3	1	UBE2D1	0	affinity chromatography technology, two hybrid, pull down, pull down, pull down, pull down	Hu S (2003), Dynek JN (2010), Dynek JN (2010), Bertrand MJ (2011), Hu S (2006), Guicciardi ME (2014)	6
TES	1	USP9X	15	affinity chromatography technology	Sala S (2017)	1
WWP2	7	ITCH	1	affinity chromatography technology	Chaudhary N (2014)	1
SMN2	0	GEMIN4	2	affinity chromatography technology	Han KJ (2012)	1
MARCH7	0	UBE2D1	0	two hybrid	Flach K (2014)	1
SOX2	4	XPO1	8	pull down	Baltus GA (2009)	1
USP34	7	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
ASB15	1	PRPF8	14	affinity chromatography technology	Andresen CA (2014)	1
ZNF598	6	UBE2D2	0	affinity chromatography technology	Garzia A (2017)	1
TRIM25	5	USP9X	15	affinity chromatography technology	Choudhury NR (2017)	1
AMOTL2	5	YAP1	0	affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Paramasivam M (2011), Couzens AL (2013), Couzens AL (2013), Hauri S (2013), Kim M (2016), Enzo E (2015)	6
HUWE1	22	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down	Zhang J (2011), Adhikary S (2005), Schwarz SE (1998), Chen D (2005), Kristariyanto YA (2015), Lee CK (2015), Zhao X (2008)	7
SMURF1	4	UBE2L3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Cao Y (2014), Xie P (2014), Anindya R (2007), Kristariyanto YA (2015), Zhang W (2016), Andrews PS (2010), He S (2017), Zhang Y (2017)	8
PTPN14	5	USP9X	15	affinity chromatography technology	Li X (2016)	1
CSNK1E	0	USP9X	15	affinity chromatography technology	Varjosalo M (2013)	1
NANOG	0	SOX2	4	affinity chromatography technology	Oliviero G (2015)	1
IGBP1	1	TES	1	biochemical	Havugimana PC (2012)	1
CFTR	5	MTOR	14	affinity chromatography technology	Pankow S (2015)	1
ALKBH3	1	USP9X	15	affinity chromatography technology	Zhao Y (2015)	1
CAND1	2	SEC24C	2	affinity chromatography technology	Bennett EJ (2010)	1
NANOG	0	MAGED1	0	affinity chromatography technology	Oliviero G (2015)	1
AURKA	1	MAP3K5	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
XPO1	8	PEX5	2	affinity chromatography technology	Kirli K (2015)	1
AURKA	1	SIRT7	1	affinity chromatography technology	Hein MY (2015)	1
UNK	3	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
TERF1	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
RASSF10	2	PRICKLE1	0	affinity chromatography technology	Hauri S (2013)	1
SSSCA1	0	GEMIN5	1	affinity chromatography technology	Huttlin EL (2017)	1
WWP2	7	AMOTL1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Chaudhary N (2014), Huttlin EL (2017)	3
PSMB4	2	PSMB8	0	two hybrid, biochemical, biochemical, biochemical	Fricke B (2007), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015)	4
TERF2	2	CLK3	0	affinity chromatography technology	Giannone RJ (2010)	1
UBC	7	UBXN7	3	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Kelsall IR (2013), Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	4
SMURF1	4	UBQLN1	1	enzymatic study	Andrews PS (2010)	1
CSNK1E	0	CRY1	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Wallach T (2013), Hein MY (2015), Huttlin EL (2017)	4
NFX1	2	USP9X	15	affinity chromatography technology	Katzenellenbogen RA (2007)	1
EGLN3	0	IRS4	2	affinity chromatography technology	Rodriguez J (2016)	1
SMAD1	0	YAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Alarcon C (2009), Alarcon C (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011)	5
SUV39H1	0	USP9X	15	affinity chromatography technology	Huttlin EL (2017)	1
SIRT7	1	AFDN	10	affinity chromatography technology	Tsai YC (2012)	1
CFTR	5	IRS4	2	affinity chromatography technology	Pankow S (2015)	1
NTRK1	1	CSNK1E	0	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
CSNK1E	0	AHCYL1	2	affinity chromatography technology	Varjosalo M (2013)	1
BCL10	0	USP9X	15	affinity chromatography technology	Park Y (2013)	1
ZYX	2	SEC24C	2	biochemical	Kristensen AR (2012)	1
ERG	1	CUL3	17	affinity chromatography technology	Gan W (2015)	1
UBC	7	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study	Nathan JA (2013), Bish RA (2007), Thompson JW (2014), Kristariyanto YA (2015), Zhang X (2017), Michel MA (2017)	6
SRXN1	0	SSSCA1	0	biochemical	Havugimana PC (2012)	1
CCDC8	1	CAND1	2	affinity chromatography technology	Hanson D (2014)	1
IQCB1	3	GEMIN4	2	affinity chromatography technology	Sang L (2011)	1
EGLN3	0	SAV1	0	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	CAND1	2	affinity chromatography technology	Choudhury NR (2017)	1
ITCH	1	SMAD2	5	enzymatic study, affinity chromatography technology	Bai Y (2004), Bai Y (2004)	2
TERF2	2	TERF1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Giannone RJ (2010), Ye JZ (2004), Ye JZ (2004)	3
NEK6	2	LNX1	7	two hybrid	Rolland T (2014)	1
EGLN3	0	RICTOR	4	affinity chromatography technology	Rodriguez J (2016)	1
SMN2	0	GEMIN8	1	affinity chromatography technology, affinity chromatography technology	Han KJ (2012), Huttlin EL (2017)	2
AMOT	6	WWC1	5	bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Hauri S (2013), Toloczko A (2017)	3
UBE2D2	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
AURKA	1	HDAC6	0	enzymatic study, pull down	Pugacheva EN (2007), Pugacheva EN (2007)	2
SOD1	0	UBE2L3	1	biochemical	Wan C (2015)	1
USP9X	15	TCP1	0	biochemical	Kristensen AR (2012)	1
HUWE1	22	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010)	3
AHCYL1	2	USP9X	15	biochemical	Havugimana PC (2012)	1
HDAC5	4	XPO1	8	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Kirli K (2015)	2
NTRK1	1	HUWE1	22	affinity chromatography technology	Emdal KB (2015)	1
WWP2	7	AMOT	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Chaudhary N (2014), Huttlin EL (2017)	3
XPO1	8	USP9X	15	affinity chromatography technology	Kirli K (2015)	1
CCDC8	1	TRIM25	5	affinity chromatography technology	Hanson D (2014)	1
NANOG	0	USP9X	15	affinity chromatography technology	Oliviero G (2015)	1
IGBP1	1	TCP1	0	affinity chromatography technology, affinity chromatography technology	Gingras AC (2005), Hein MY (2015)	2
USP9X	15	SMN2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Han KJ (2012), Han KJ (2012), Han KJ (2012), Han KJ (2012)	4
TERF2	2	IRS4	2	affinity chromatography technology	Giannone RJ (2010)	1
CFTR	5	USP9X	15	affinity chromatography technology	Wang X (2006)	1
CASP4	1	USP9X	15	affinity chromatography technology	Ewing RM (2007)	1
USP9X	15	PEX5	2	enzymatic study	Grou CP (2012)	1
SOD1	0	UBC	7	affinity chromatography technology	Urushitani M (2004)	1
SMAD3	1	PJA1	1	affinity chromatography technology	Brown KA (2008)	1
EGLN3	0	MCL1	1	affinity chromatography technology	Rodriguez J (2016)	1
ZNHIT2	0	UBR4	15	affinity chromatography technology	Cloutier P (2017)	1
EGLN3	0	CCT4	2	affinity chromatography technology	Rodriguez J (2016)	1
HDAC5	4	CAND1	2	affinity chromatography technology	Greco TM (2011)	1
CCDC8	1	RUVBL1	2	affinity chromatography technology	Hanson D (2014)	1
RPS6KB2	3	CCT4	2	affinity chromatography technology	Roy R (2014)	1
UBE2L3	1	UBXN1	0	biochemical	Havugimana PC (2012)	1
UBE2L3	1	YAP1	0	biochemical	Havugimana PC (2012)	1
SHC1	0	ELP1	5	affinity chromatography technology	Brehme M (2009)	1
DDX20	4	GEMIN8	1	affinity chromatography technology	Huttlin EL (2017)	1
SOX2	4	AHCYL1	2	affinity chromatography technology	Cox JL (2013)	1
MCL1	1	USP9X	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology	Gomez-Bougie P (2011), Gomez-Bougie P (2011), Schwickart M (2010), Schwickart M (2010), Schwickart M (2010), Zhang C (2011), Trivigno D (2012), Peddaboina C (2012)	8
XPO1	8	KIAA0368	0	biochemical	Wan C (2015)	1
BIRC2	1	UBXN1	0	affinity chromatography technology, affinity chromatography technology	Wang YB (2015), Wang YB (2015)	2
CUL3	17	TCP1	0	affinity chromatography technology	Bennett EJ (2010)	1
ALKBH3	1	OTUD4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhao Y (2015), Zhao Y (2015), Zhao Y (2015), Zhao Y (2015)	4
GEMIN5	1	GEMIN2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gubitz AK (2002), Piazzon N (2012), Piazzon N (2012), Piazzon N (2012), Hein MY (2015)	5
HEXIM2	0	AHCYL1	2	affinity chromatography technology	Huttlin EL (2017)	1
XPO1	8	RICTOR	4	affinity chromatography technology	Kirli K (2015)	1
UBA52	0	UFM1	0	biochemical	Havugimana PC (2012)	1
UBXN1	0	UBXN7	3	affinity chromatography technology	Raman M (2015)	1
UBE2D2	0	UBC	7	x-ray crystallography, x-ray crystallography, enzymatic study, pull down, pull down	Juang YC (2012), Dou H (2012), Sheng Y (2012), Buetow L (2015), Zhang X (2017)	5
EGLN3	0	KIAA0368	0	affinity chromatography technology	Rodriguez J (2016)	1
IQCB1	3	MARCH7	0	affinity chromatography technology, affinity chromatography technology, pull down	Das A (2017), Das A (2017), Das A (2017)	3
CRY1	0	CRY2	2	affinity chromatography technology, affinity chromatography technology	Papp SJ (2015), Huttlin EL (2017)	2
SAV1	0	IRS4	2	affinity chromatography technology	Couzens AL (2013)	1
SMURF1	4	SMAD1	0	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, pull down, unspecified method, two hybrid, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Sangadala S (2006), Komuro A (2004), Tian M (2011), Tian M (2011), Tian M (2011), Sapkota G (2007), Sapkota G (2007), Li L (2004), Alarcon C (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011), Aragon E (2011), Gao S (2009), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Colland F (2004), Cao Y (2014), Cao Y (2014), Sangadala S (2007), Gao S (2009), Wan L (2011), Wan L (2011), Zhang Y (2017), Zhang Y (2017)	28
XPO1	8	AHCYL1	2	affinity chromatography technology	Kirli K (2015)	1
UBE2D2	0	CUL3	17	pull down	Plafker KS (2009)	1
ZNF598	6	CCT4	2	affinity chromatography technology	Garzia A (2017)	1
NTRK1	1	DCX	5	affinity chromatography technology	Emdal KB (2015)	1
HECW2	13	AMOT	6	affinity chromatography technology	Choi KS (2016)	1
EGFR	5	UBR4	15	affinity chromatography technology	Tong J (2014)	1
CCDC8	1	CTNNB1	30	affinity chromatography technology	Hanson D (2014)	1
TRIM25	5	UBE4B	5	affinity chromatography technology	Choudhury NR (2017)	1
UBE2C	1	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
IGBP1	1	UBE2B	3	biochemical	Havugimana PC (2012)	1
ZNHIT2	0	PRPF8	14	bioid, affinity chromatography technology	Cloutier P (2017), Cloutier P (2017)	2
PTPN14	5	VHL	0	affinity chromatography technology	Wang W (2012)	1
ZNF746	0	SNRNP200	15	affinity chromatography technology	Kang H (2015)	1
MALT1	1	BCL10	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uren AG (2000), Uren AG (2000), Uren AG (2000), Noels H (2009), Carvalho G (2010), Welteke V (2009), Oruganti SR (2011), Lucas PC (2001), Langel FD (2008), Langel FD (2008), Blonska M (2007), Oeckinghaus A (2007), Park Y (2013), Park Y (2013), Borthakur A (2013), Zhou H (2004), Zhou H (2004), Chen J (2015), Karim ZA (2015), Nie Z (2015), Eitelhuber AC (2011), Paul S (2012), Yang YK (2016), Liu Y (2012), Bidere N (2009), Bidere N (2009), Afonina IS (2016), Howes A (2016)	28
NTRK1	1	KIAA0368	0	affinity chromatography technology	Emdal KB (2015)	1
UCHL3	1	CDH1	4	enzymatic study	Ponce E (2014)	1
SNCA	0	USP9X	15	affinity chromatography technology, affinity chromatography technology	Rott R (2011), Rott R (2011)	2
UBE2B	3	UNK	3	biochemical, affinity chromatography technology	Havugimana PC (2012), Murn J (2015)	2
SEC23A	3	USP9X	15	biochemical	Havugimana PC (2012)	1
CAND1	2	USP9X	15	affinity chromatography technology	Bennett EJ (2010)	1
UBXN1	0	BIRC3	1	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Wang YB (2015)	2
NANOG	0	SMAD4	9	affinity chromatography technology	Oliviero G (2015)	1
HUWE1	22	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Thompson JW (2014), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017)	4
PEG10	2	USP9X	15	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AHCYL1	2	SOD1	0	biochemical	Havugimana PC (2012)	1
XPO1	8	MTOR	14	affinity chromatography technology	Kirli K (2015)	1
TRIM25	5	SMAD4	9	affinity chromatography technology	Choudhury NR (2017)	1
BIRC3	1	UBC	7	pull down, pull down, enzymatic study	Gyrd-Hansen M (2008), Nakatani Y (2012), Sakamoto H (2015)	3
EGLN3	0	IGBP1	1	affinity chromatography technology	Rodriguez J (2016)	1
LATS2	1	YAP1	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study	Ikeda M (2009), Zhang J (2008), Zhang J (2008), Vigneron AM (2010), Vigneron AM (2010), Bao Y (2009), Kawahara M (2008), Paramasivam M (2011), Aylon Y (2010), Oka T (2008), Yu FX (2012), Mo XL (2015), Rashidian J (2015), Kim M (2016), Enzo E (2015), Si Y (2017), Ivanov AA (2017), Zhu C (2018)	18
SIRT7	1	PRPF8	14	affinity chromatography technology	Tsai YC (2012)	1
IGBP1	1	UNK	3	biochemical	Havugimana PC (2012)	1
SNRNP200	15	USP9X	15	biochemical	Havugimana PC (2012)	1
CAND1	2	MCM2	3	affinity chromatography technology	Bennett EJ (2010)	1
YAP1	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
HDAC6	0	IQCB1	3	affinity chromatography technology	Joshi P (2013)	1
UBE2V2	0	ZYX	2	biochemical	Havugimana PC (2012)	1
MCM2	3	CCT4	2	affinity chromatography technology	Drissi R (2015)	1
SNRNP200	15	UBR4	15	biochemical	Havugimana PC (2012)	1
XPO1	8	RUVBL1	2	affinity chromatography technology	Kirli K (2015)	1
CCDC8	1	SNRNP200	15	affinity chromatography technology	Hanson D (2014)	1
RPS6KB2	3	RUVBL1	2	affinity chromatography technology	Roy R (2014)	1
DCX	5	USP9X	15	two hybrid, affinity chromatography technology, affinity chromatography technology	Friocourt G (2005), Friocourt G (2005), Friocourt G (2005)	3
UBE2B	3	UBA52	0	biochemical	Havugimana PC (2012)	1
CFTR	5	PSMB8	0	affinity chromatography technology	Pankow S (2015)	1
CTNNB1	30	GEMIN5	1	affinity chromatography technology	Sato S (2005)	1
DDX20	4	SNRPB	0	affinity chromatography technology, pull down	Charroux B (1999), Charroux B (1999)	2
UBE2B	3	USP9X	15	biochemical	Havugimana PC (2012)	1
UBE2B	3	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
SMAD2	5	UBA52	0	two hybrid	Colland F (2004)	1
MCM2	3	UBE2D1	0	affinity chromatography technology	Drissi R (2015)	1
UNK	3	MCL1	1	affinity chromatography technology	Murn J (2015)	1
SAV1	0	UNK	3	bioid	Couzens AL (2013)	1
UBE2V2	0	UBXN1	0	biochemical	Havugimana PC (2012)	1
CUL3	17	SAV1	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D1	0	UBQLN1	1	biochemical	Havugimana PC (2012)	1
UBR4	15	USP9X	15	biochemical	Havugimana PC (2012)	1
UBE2D1	0	UBL7	0	biochemical	Havugimana PC (2012)	1
BIRC3	1	BCL10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Yoneda T (2000), Hu S (2006), Yui D (2001), Hu S (2006), Hu S (2006), Hu S (2006), Hu S (2006)	7
GRK5	7	GEMIN4	2	affinity chromatography technology	Wu Z (2012)	1
UBE2D1	0	HDAC6	0	enzymatic study	Hoeller D (2007)	1
POU5F1	0	HUWE1	22	affinity chromatography technology	Oliviero G (2015)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
UCHL3	1	UBC	7	enzymatic study, enzymatic study, enzymatic study, x-ray crystallography, pull down, x-ray crystallography, pull down, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, pull down, pull down	Bremm A (2010), Boudreaux D (2012), Misaghi S (2005), Misaghi S (2005), Wilkinson KD (1999), Wilkinson KD (1999), Phillips AH (2013), Larsen CN (1998), Wada H (1998), Hemelaar J (2004), Altun M (2015), Flierman D (2016), Zhang X (2017), Kwasna D (2018), Lee YC (2017), Lee YC (2017), Hanpude P (2017)	17
SMURF1	4	CCT4	2	affinity chromatography technology	Xie Y (2013)	1
AHCYL1	2	UBE4B	5	biochemical	Havugimana PC (2012)	1
RPTOR	4	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Rosner M (2010), Rosner M (2010)	2
UFC1	0	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
UBC	7	USP34	7	pull down	Kwasna D (2018)	1
SMAD2	5	AFDN	10	two hybrid	Colland F (2004)	1
UBA52	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
WWC1	5	CSNK1E	0	affinity chromatography technology	Toloczko A (2017)	1
CLK3	0	USP9X	15	affinity chromatography technology	Varjosalo M (2013)	1
CDH1	4	RUVBL1	2	bioid	Guo Z (2014)	1
AMOT	6	ITCH	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang C (2012), Wang C (2012), Adler JJ (2013), Adler JJ (2013), Adler JJ (2013)	5
RUVBL1	2	SNRNP200	15	affinity chromatography technology	Cloutier P (2017)	1
ITCH	1	GEMIN8	1	affinity chromatography technology	Han KJ (2016)	1
UBXN7	3	ZFYVE19	0	biochemical	Havugimana PC (2012)	1
TRIM25	5	ZNF598	6	affinity chromatography technology	Choudhury NR (2017)	1
MIB1	5	USP9X	15	affinity chromatography technology	Wang J (2013)	1
SMURF1	4	UBQLN2	0	enzymatic study	Andrews PS (2010)	1
NTRK1	1	SUPV3L1	2	affinity chromatography technology	Emdal KB (2015)	1
UBE2D2	0	UFM1	0	two hybrid	van Wijk SJ (2009)	1
CFTR	5	PSMB4	2	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
UBE2B	3	ZYX	2	biochemical	Havugimana PC (2012)	1
CCDC8	1	HUWE1	22	affinity chromatography technology	Hanson D (2014)	1
TES	1	HUWE1	22	affinity chromatography technology	Sala S (2017)	1
TES	1	CTNNB1	30	affinity chromatography technology	Sala S (2017)	1
UBE2D2	0	PJA1	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yu P (2002), Yu P (2002), Yu P (2002), Loch CM (2011)	4
CUL3	17	HUWE1	22	affinity chromatography technology	Bennett EJ (2010)	1
RUVBL1	2	ZNHIT2	0	affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Cloutier P (2017), Cloutier P (2017), Cloutier P (2017)	4
XPO1	8	WWC1	5	affinity chromatography technology	Kirli K (2015)	1
UBE2C	1	UBQLN1	1	biochemical	Havugimana PC (2012)	1
ITCH	1	SMAD3	1	pull down	Feng L (2004)	1
HDAC5	4	PRPF8	14	affinity chromatography technology	Greco TM (2011)	1
SMAD4	9	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Moren A (2005), Zhang L (2013)	2
ZYX	2	LATS1	3	affinity chromatography technology, pull down	Hirota T (2000), Hirota T (2000)	2
CCDC8	1	MCM2	3	affinity chromatography technology	Hanson D (2014)	1
BIRC3	1	EGFR	5	affinity chromatography technology	Puliyappadamba VT (2013)	1
NTRK1	1	CAND1	2	affinity chromatography technology	Emdal KB (2015)	1
CAND1	2	SNRNP200	15	affinity chromatography technology	Bennett EJ (2010)	1
CLK3	0	GEMIN2	1	affinity chromatography technology	Huttlin EL (2017)	1
ERG	1	SNRNP200	15	affinity chromatography technology, pull down	Wang S (2014), Wang S (2014)	2
LATS2	1	KIAA0368	0	bioid	Couzens AL (2013)	1
UNK	3	CTNNB1	30	affinity chromatography technology	Murn J (2015)	1
TERF1	1	NUDCD2	2	two hybrid	Lee OH (2011)	1
XPO1	8	CRY2	2	affinity chromatography technology, affinity chromatography technology	Kirli K (2015), Papp SJ (2015)	2
EGLN3	0	ECT2	2	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	MTOR	14	affinity chromatography technology	Foerster S (2013)	1
CFTR	5	UBR4	15	affinity chromatography technology	Pankow S (2015)	1
UBE2D1	0	YAP1	0	biochemical	Havugimana PC (2012)	1
ITCH	1	UBE2D1	0	pull down	Kristariyanto YA (2015)	1
USP9X	15	ATP6V1F	1	biochemical	Havugimana PC (2012)	1
RUVBL1	2	PRPF8	14	affinity chromatography technology	Cloutier P (2017)	1
TRIM25	5	SNRPB	0	affinity chromatography technology	Choudhury NR (2017)	1
PTPN14	5	YAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang W (2012), Wang W (2012), Wang W (2012), Wang W (2012), Couzens AL (2013), Hauri S (2013), Schuchardt BJ (2014), Li X (2016), Huttlin EL (2017), Li X (2016), Enzo E (2015)	11
UBL7	0	UBQLN2	0	biochemical	Havugimana PC (2012)	1
WWC1	5	LATS2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xiao L (2011), Xiao L (2011), Wennmann DO (2014)	3
SSSCA1	0	UBA52	0	biochemical	Havugimana PC (2012)	1
TRIM25	5	CLK3	0	affinity chromatography technology	Choudhury NR (2017)	1
NUBP2	0	USP9X	15	biochemical	Havugimana PC (2012)	1
LATS1	3	AMOT	6	bioid, enzymatic study, affinity chromatography technology	Couzens AL (2013), Adler JJ (2013), Hauri S (2013)	3
PTPN14	5	WWC1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang W (2012), Wilson KE (2014), Wilson KE (2014), Hauri S (2013), Li X (2016), Toloczko A (2017)	6
XPO1	8	SMAD4	9	affinity chromatography technology	Kirli K (2015)	1
HDAC5	4	IRS4	2	affinity chromatography technology	Greco TM (2011)	1
TTLL12	3	UBE2B	3	biochemical	Havugimana PC (2012)	1
CFTR	5	CCT4	2	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
CRY1	0	HUWE1	22	affinity chromatography technology	Papp SJ (2015)	1
CUL3	17	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Chua YS (2011), Chua YS (2011), Tron AE (2012), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Schumacher FR (2015), Schumacher FR (2015), Lo SC (2006), Lo SC (2006)	12
SMAD1	0	UBC	7	two hybrid	Guo X (2001)	1
SMURF1	4	VHL	0	affinity chromatography technology	Zhang C (2016)	1
SMAD1	0	USP9X	15	affinity chromatography technology	Dupont S (2009)	1
YAP1	0	PRPF8	14	affinity chromatography technology	Enzo E (2015)	1
UBE2C	1	USP34	7	biochemical	Havugimana PC (2012)	1
CCDC8	1	IRS4	2	affinity chromatography technology	Hanson D (2014)	1
MALT1	1	UBE2V2	0	pull down	Zhou H (2004)	1
UNK	3	CAND1	2	affinity chromatography technology	Murn J (2015)	1
SMAD2	5	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe	Brown KA (2008), Wu RY (1997), Wu RY (1997), Ivanov AA (2017)	4
EGLN3	0	MAGED1	0	affinity chromatography technology	Rodriguez J (2016)	1
SMN2	0	GEMIN2	1	affinity chromatography technology	Han KJ (2012)	1
TRIM25	5	RICTOR	4	affinity chromatography technology	Choudhury NR (2017)	1
SAV1	0	CSNK1E	0	affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Varjosalo M (2013)	2
MCM2	3	CTNNB1	30	affinity chromatography technology	Drissi R (2015)	1
ITCH	1	USP9X	15	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Mouchantaf R (2006), Mouchantaf R (2006), Azakir BA (2009), OConnor HF (2015)	4
HUWE1	22	TCP1	0	affinity chromatography technology	Thompson JW (2014)	1
EGFR	5	USP34	7	affinity chromatography technology	Yao Z (2017)	1
UBA52	0	USP9X	15	biochemical	Havugimana PC (2012)	1
CRY1	0	CCT4	2	affinity chromatography technology	Papp SJ (2015)	1
POU5F1	0	SOX2	4	pull down, affinity chromatography technology, affinity chromatography technology	Remenyi A (2003), Xu C (2013), Oliviero G (2015)	3
MCM2	3	SNRNP200	15	affinity chromatography technology	Drissi R (2015)	1
ZNF746	0	PRPF8	14	affinity chromatography technology	Kang H (2015)	1
TERF1	1	MTOR	14	affinity chromatography technology	Takai H (2007)	1
XPO1	8	HEXIM2	0	affinity chromatography technology	Kirli K (2015)	1
UBE2D1	0	CAND1	2	biochemical	You J (2001)	1
XPO1	8	ZNHIT2	0	affinity chromatography technology	Kirli K (2015)	1
BIRC2	1	UBR4	15	affinity chromatography technology	Goncharov T (2013)	1
CUL3	17	USP9X	15	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	MIB1	5	two hybrid, pull down	van Wijk SJ (2009), McMillan BJ (2015)	2
BIRC3	1	USP9X	15	affinity chromatography technology	Goncharov T (2013)	1
UFM1	0	ZFYVE19	0	biochemical	Havugimana PC (2012)	1