Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
PICALM rs588076 GG calcium channel blockers efficacy yes Increased response as determined by a greater decrease in both systolic and diastolic blood pressure. Please note; this gene is on the minus strand, abd the alleles have been complemented from those reported in the article because the G allele is the major allele on the plus chromosomal strand. The major allele was associated with a better response. Genotype GG is associated with increased response to calcium channel blockers in people with Hypertension as compared to genotype CC. 24192120 1183688854