PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
LGALS3BP	5	MAGED2	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Fogeron ML (2013)	2
CFTR	5	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vij N (2006), Ballar P (2010), Goldstein RF (2007), Goldstein RF (2007), Sun F (2006), Sun F (2006), Wang X (2006), Morito D (2008), Pankow S (2015)	9
RIPK4	0	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
YWHAE	0	CEP250	4	affinity chromatography technology	Gloeckner CJ (2007)	1
ILK	0	RAF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Hein MY (2015)	3
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
IRS4	2	HSPA4	3	affinity chromatography technology	Sano H (2002)	1
MAGED1	0	AKAP8L	1	affinity chromatography technology	Ewing RM (2007)	1
HDAC5	4	TBL1XR1	23	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Joshi P (2013)	2
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
CCDC8	1	AURKB	2	affinity chromatography technology	Hanson D (2014)	1
YWHAQ	0	YWHAG	5	affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Kristensen AR (2012)	2
SAV1	0	YWHAE	0	affinity chromatography technology	Couzens AL (2013)	1
HSP90AA1	7	TERF1	1	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	RCN1	0	affinity chromatography technology	Bennett EJ (2010)	1
DUSP16	0	YWHAB	1	affinity chromatography technology, affinity chromatography technology	Li X (2016), Yadav L (2017)	2
PIK3R2	3	PIK3CA	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Kuchay S (2013), Hein MY (2015)	3
CUL3	17	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
EMD	0	WDR6	6	affinity chromatography technology	Fogeron ML (2013)	1
RNF41	2	P4HA1	1	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	AURKB	2	affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Krupina K (2016)	2
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
DLD	1	PTGES3	0	affinity chromatography technology	Malty RH (2017)	1
TERF2	2	USP9X	15	affinity chromatography technology	Giannone RJ (2010)	1
NPHP4	10	RAF1	3	affinity chromatography technology	Boldt K (2016)	1
HDAC5	4	TUBA1A	13	affinity chromatography technology	Greco TM (2011)	1
PPP5C	2	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Zeke T (2005), Silverstein AM (1997), Schuelke JP (2010), Gano JJ (2010), Cliff MJ (2006), Skarra DV (2011), Skarra DV (2011), Horibe T (2011), Taipale M (2014), Taipale M (2014), Hein MY (2015), Woo SH (2009), Woo SH (2009), Woodford MR (2016), St-Denis N (2016), Yadav L (2017), Yadav L (2017)	17
IRS4	2	PIK3CA	8	affinity chromatography technology	Sano H (2002)	1
EGLN3	0	GBF1	4	affinity chromatography technology	Rodriguez J (2016)	1
PTPN18	1	CTSB	5	affinity chromatography technology	Li X (2016)	1
PIK3R1	6	PIK3CA	8	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Woscholski R (1994), Chamberlain MD (2004), Ren SY (2005), Kamal M (2010), Sun M (2010), Hein MY (2015), Fang D (2001), Xiong Y (2009), Ivanov AA (2017)	9
ERBB2	6	CRK	0	unspecified method	Jones RB (2006)	1
HDAC5	4	USP9X	15	affinity chromatography technology	Greco TM (2011)	1
VCP	6	YWHAE	0	affinity chromatography technology	Yu CC (2013)	1
SAV1	0	USP9X	15	affinity chromatography technology, affinity chromatography technology	Toloczko A (2017), Toloczko A (2017)	2
CCDC8	1	STAU1	1	affinity chromatography technology	Hanson D (2014)	1
PIK3R2	3	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Martelli MP (2001)	3
EGFR	5	RCN2	0	affinity chromatography technology	Foerster S (2013)	1
HSP90AA1	7	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
RNF41	2	IRS4	2	two hybrid	Wijesuriya TM (2017)	1
HDAC5	4	YWHAG	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carnegie GK (2008), Greco TM (2011), Joshi P (2013)	3
VCP	6	YWHAH	0	affinity chromatography technology	Yu CC (2013)	1
PPEF1	1	P4HA1	1	affinity chromatography technology	Yadav L (2017)	1
SIRT7	1	WDR6	6	affinity chromatography technology	Tsai YC (2012)	1
IRS4	2	HSPB1	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
COPS5	0	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	CTSB	5	two hybrid	Vinayagam A (2011)	1
PAN2	3	YWHAE	0	affinity chromatography technology	Bett JS (2013)	1
EGLN3	0	CACYBP	0	affinity chromatography technology	Rodriguez J (2016)	1
CUL1	7	TUBB4A	3	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	ILK	0	affinity chromatography technology	Rodriguez J (2016)	1
PPEF1	1	TUBB4A	3	affinity chromatography technology	Yadav L (2017)	1
IRS4	2	CACYBP	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TMEM17	0	YWHAH	0	bioid	Gupta GD (2015)	1
CUL2	3	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	CUL1	7	affinity chromatography technology	von der Lehr N (2003)	1
FBXO7	1	TUBB6	2	affinity chromatography technology	Teixeira FR (2016)	1
IRS4	2	MAGEL2	6	two hybrid	Wijesuriya TM (2017)	1
RMND5A	0	IRS4	2	affinity chromatography technology	Lampert F (2018)	1
PAN2	3	TUBA1A	13	affinity chromatography technology	Bett JS (2013)	1
RIPK4	0	MAGED1	0	affinity chromatography technology	Rodriguez J (2016)	1
ILK	0	AKAP8L	1	affinity chromatography technology	Varjosalo M (2013)	1
CDKN1A	1	OTUB1	0	two hybrid	Vinayagam A (2011)	1
EMD	0	YWHAQ	0	affinity chromatography technology	Holaska JM (2007)	1
VCP	6	RAF1	3	affinity chromatography technology	Yu CC (2013)	1
RIPK4	0	IRS4	2	affinity chromatography technology	Rodriguez J (2016)	1
VCP	6	YWHAG	5	affinity chromatography technology	Yu CC (2013)	1
TMEM17	0	IRS4	2	bioid	Gupta GD (2015)	1
FBXO7	1	MAGED1	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kang J (2014), Kang J (2014), Kang J (2014), Teixeira FR (2016)	4
IRS4	2	TUBB4A	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
FKBP5	0	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CFTR	5	RCN2	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
HSP90AA1	7	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu W (2001), Jeong JH (2008), Mollapour M (2010), Citri A (2002), Jung Y (2007), Suzuki T (2011), Tsutsumi S (2012), Taipale M (2012), Bali P (2005), Woodford MR (2016), Yan YY (2011), Yan YY (2011)	12
MTNR1A	1	RNF41	2	two hybrid	Benleulmi-Chaachoua A (2016)	1
RIPK4	0	RAF1	3	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Zhang Z (2016)	2
YWHAG	5	PIK3R1	6	affinity chromatography technology	Jin J (2004)	1
ZNF598	6	IRS4	2	affinity chromatography technology	Garzia A (2017)	1
IRS4	2	PIK3R3	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HSPB1	2	PTGES3	0	two hybrid	Katsogiannou M (2014)	1
CFTR	5	EMD	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
RIPK4	0	HSP90AA1	7	affinity chromatography technology	Rodriguez J (2016)	1
FBXO7	1	PINK1	2	affinity chromatography technology, pull down	Burchell VS (2013), Burchell VS (2013)	2
NPHP4	10	IRS4	2	bioid	Gupta GD (2015)	1
DNAJA3	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen CY (2013), Foerster S (2013), Tong J (2014)	3
ILK	0	CALU	4	affinity chromatography technology	So J (2015)	1
HDAC5	4	YWHAE	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Grozinger CM (2000), Greco TM (2011), Joshi P (2013), Greco TM (2011), Lee CW (2014)	5
IRS4	2	MAGED1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TUBA1A	13	YWHAZ	1	genetic interference	Srivas R (2016)	1
EGFR	5	USP9X	15	affinity chromatography technology	Foerster S (2013)	1
NF2	1	TUBB4A	3	affinity chromatography technology	Zhou L (2015)	1
CUL3	17	PIK3R2	3	affinity chromatography technology	Bennett EJ (2010)	1
MTNR1B	1	IRS4	2	pull down	Benleulmi-Chaachoua A (2016)	1
CFTR	5	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
RAF1	3	COPS5	0	affinity chromatography technology	Hein MY (2015)	1
CDKN1A	1	YWHAQ	0	affinity chromatography technology, affinity chromatography technology, pull down	Wang B (2010), Wang B (2010), Wang B (2010)	3
COX15	3	IRS4	2	affinity chromatography technology	Malty RH (2017)	1
EGFR	5	YWHAB	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
HSP90AA1	7	MAGED2	1	biochemical	Kristensen AR (2012)	1
GRB2	2	VCP	6	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
TMEM216	0	IRS4	2	bioid	Gupta GD (2015)	1
EGLN3	0	PDHA1	7	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	RCN2	0	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	MAGED2	1	affinity chromatography technology	Rodriguez J (2016)	1
PTEN	24	IRS4	2	affinity chromatography technology, affinity chromatography technology	Crockett DK (2005), Crockett DK (2005)	2
CFTR	5	YWHAG	5	affinity chromatography technology	Pankow S (2015)	1
NF2	1	IRS4	2	affinity chromatography technology	Zhou L (2015)	1
MTNR1B	1	YWHAQ	0	pull down	Benleulmi-Chaachoua A (2016)	1
ERBB2	6	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CEP250	4	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	AURKA	1	affinity chromatography technology	Moghe S (2012)	1
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
HSP90AA1	7	CFTR	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fuller W (2000), Goldstein RF (2007), Goldstein RF (2007), Sun F (2008), Wang X (2006)	5
CUL3	17	AKAP8L	1	affinity chromatography technology	Bennett EJ (2010)	1
RNF41	2	MAGEL2	6	two hybrid	Wijesuriya TM (2017)	1
IRS4	2	PTGES3	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGFR	5	EMD	0	biochemical, affinity chromatography technology, affinity chromatography technology	Wang YN (2010), Tong J (2014), Yao Z (2017)	3
CFTR	5	YWHAH	0	affinity chromatography technology	Pankow S (2015)	1
RIPK4	0	P4HA1	1	affinity chromatography technology	Rodriguez J (2016)	1
TUBGCP3	1	LGALS3BP	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Fogeron ML (2013), Fogeron ML (2013), Hein MY (2015), Huttlin EL (2017)	5
YWHAG	5	TERF1	1	two hybrid, two hybrid	Bandyopadhyay S (2010), Lee OH (2011)	2
CUL2	3	YWHAQ	0	affinity chromatography technology	Bennett EJ (2010)	1
HDAC5	4	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Joshi P (2013)	2
FBXO7	1	DNAJA3	2	affinity chromatography technology, enzymatic study	Teixeira FR (2016), Teixeira FR (2016)	2
CCDC8	1	HSPA4	3	affinity chromatography technology	Hanson D (2014)	1
PPEF1	1	EMD	0	affinity chromatography technology	Yadav L (2017)	1
EGFR	5	HSPA4	3	protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Deribe YL (2009), Deribe YL (2009), Citri A (2002), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014)	6
FBXO7	1	LGALS3BP	5	enzymatic study	Teixeira FR (2016)	1
COPS5	0	MAGED2	1	affinity chromatography technology	Bennett EJ (2010)	1
ZNF598	6	DNAJA2	2	affinity chromatography technology	Garzia A (2017)	1
MTNR1A	1	EMD	0	two hybrid	Benleulmi-Chaachoua A (2016)	1
IRS4	2	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	NISCH	11	affinity chromatography technology	Rodriguez J (2016)	1
FBXO7	1	ERBB2	6	enzymatic study	Teixeira FR (2016)	1
DUSP16	0	AKAP8L	1	affinity chromatography technology	Yadav L (2017)	1
YWHAG	5	COPS5	0	two hybrid	Bandyopadhyay S (2010)	1
NEDD1	1	TUBG1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Hein MY (2015), Hein MY (2015)	3
EGLN3	0	RCN2	0	affinity chromatography technology	Rodriguez J (2016)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
CEP250	4	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
HSP90AA1	7	MYC	2	affinity chromatography technology	Carystinos GD (2003)	1
PTEN	24	EGFR	5	affinity chromatography technology	Zheng J (2016)	1
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
PHLPP1	4	PPP2R1A	8	affinity chromatography technology	St-Denis N (2016)	1
PIK3R3	0	TERF2	2	two hybrid	Grossmann A (2015)	1
HDAC5	4	VCP	6	affinity chromatography technology	Greco TM (2011)	1
CUL3	17	YWHAB	1	affinity chromatography technology	Bennett EJ (2010)	1
MAPK6	1	RAF1	3	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	EMD	0	affinity chromatography technology	Bennett EJ (2010)	1
PPEF1	1	YWHAB	1	affinity chromatography technology	Yadav L (2017)	1
ZNF746	0	OTUB1	0	affinity chromatography technology	Kang H (2015)	1
OTUB1	0	IRS4	2	affinity chromatography technology	Scholz CC (2016)	1
PPP5C	2	YWHAB	1	affinity chromatography technology	Yadav L (2017)	1
HSPB1	2	YWHAH	0	two hybrid	Katsogiannou M (2014)	1
RIPK4	0	YWHAZ	1	affinity chromatography technology	Rodriguez J (2016)	1
MTMR11	2	DNAJA2	2	affinity chromatography technology	St-Denis N (2016)	1
DLD	1	PPP2R1A	8	affinity chromatography technology	Malty RH (2017)	1
CDKN1A	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
FBXO7	1	HSP90AA1	7	affinity chromatography technology	Teixeira FR (2016)	1
HAUS2	2	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
DERL1	2	IRS4	2	affinity chromatography technology	You H (2017)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
EGLN3	0	WDR6	6	affinity chromatography technology	Rodriguez J (2016)	1
CCDC8	1	VCP	6	affinity chromatography technology	Hanson D (2014)	1
NF2	1	EMD	0	affinity chromatography technology	Zhou L (2015)	1
IRS4	2	USP9X	15	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL2	3	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	GPRASP2	0	affinity chromatography technology	Rodriguez J (2016)	1
SIRT7	1	DLD	1	affinity chromatography technology	Tsai YC (2012)	1
DERL1	2	EGFR	5	affinity chromatography technology, affinity chromatography technology	Dong QZ (2013), Dong QZ (2013)	2
CEP250	4	MAGED2	1	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	YWHAG	5	affinity chromatography technology	Bennett EJ (2010)	1
CFTR	5	DERL1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun F (2006), Sun F (2006), Younger JM (2006), Wang B (2008), Pankow S (2015)	5
RIPK4	0	GBF1	4	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	CALU	4	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
COX15	3	RCN2	0	affinity chromatography technology	Malty RH (2017)	1
NEDD1	1	DERL1	2	affinity chromatography technology	Hein MY (2015)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
NEDD1	1	LGALS3BP	5	affinity chromatography technology	Hein MY (2015)	1
AURKB	2	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
ALK	8	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004), Bai RY (1998), Ambrogio C (2005), Ambrogio C (2005)	5
CUL3	17	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
COX15	3	EMD	0	affinity chromatography technology	Malty RH (2017)	1
SIRT7	1	PPP2R1A	8	affinity chromatography technology	Tsai YC (2012)	1
RIPK4	0	YWHAE	0	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	STAU1	1	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	WDR6	6	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	HSPA4	3	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Kim TS (2006), Hidalgo-de-Quintana J (2008), Skarra DV (2011), Wan C (2015)	4
CUL1	7	AKAP8L	1	affinity chromatography technology	Bennett EJ (2010)	1
RAF1	3	CALU	4	affinity chromatography technology, affinity chromatography technology	So J (2015), Hein MY (2015)	2
EGFR	5	YWHAZ	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2009), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
EGLN3	0	YWHAE	0	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	ILK	0	affinity chromatography technology	Taipale M (2012)	1
DLD	1	YWHAZ	1	affinity chromatography technology	Malty RH (2017)	1
HSPB1	2	HSPA4	3	two hybrid	Katsogiannou M (2014)	1
CUL3	17	P4HA1	1	affinity chromatography technology	Bennett EJ (2010)	1
TUBGCP3	1	NEDD1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Fogeron ML (2013), Hein MY (2015)	3
CCDC8	1	USP9X	15	affinity chromatography technology	Hanson D (2014)	1
TUBG1	2	HSPA4	3	biochemical	Wigley WC (1999)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
YWHAZ	1	COPS5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bennett EJ (2010)	2
TERF2	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009), Bhattacharyya S (2009)	3
DLD	1	IRS4	2	affinity chromatography technology	Malty RH (2017)	1
AURKA	1	MAPK6	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Rodriguez J (2016)	2
CUL3	17	VCP	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Besten Wd (2012)	2
EGLN3	0	MAPK6	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016), Rodriguez J (2016)	5
RC3H1	6	STAU1	1	affinity chromatography technology	Murakawa Y (2015)	1
EGLN3	0	AARSD1	0	affinity chromatography technology	Rodriguez J (2016)	1
YWHAB	1	YWHAZ	1	affinity chromatography technology, biochemical, affinity chromatography technology	Couzens AL (2013), Wan C (2015), Hein MY (2015)	3
RAF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	PPP2R1A	8	affinity chromatography technology	Foerster S (2013)	1
MAGED1	0	SIRT7	1	two hybrid	Stelzl U (2005)	1
PTGES3	0	PPP5C	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schuelke JP (2010), Taipale M (2014), Taipale M (2014), Yadav L (2017)	4
PDHA1	7	TP53	0	affinity chromatography technology	Malty RH (2017)	1
EGLN3	0	CALU	4	affinity chromatography technology	Rodriguez J (2016)	1
AURKA	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
IRS4	2	YWHAZ	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	AKAP8L	1	affinity chromatography technology	Rodriguez J (2016)	1
PDHA1	7	EMD	0	affinity chromatography technology	Malty RH (2017)	1
PHLPP1	4	PPP5C	2	affinity chromatography technology	Sowa ME (2009)	1
NEDD1	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	SOCS6	0	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
EGLN3	0	CRKL	1	affinity chromatography technology	Rodriguez J (2016)	1
FBXO7	1	IRS4	2	affinity chromatography technology	Teixeira FR (2016)	1
MAPK6	1	DNAJA3	2	affinity chromatography technology	Rodriguez J (2016)	1
CRK	0	SOCS6	0	two hybrid	Grossmann A (2015)	1
RNF126	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhi X (2012), Zhi X (2012), Zhi X (2012)	3
MYC	2	RAF1	3	pull down, affinity chromatography technology, fluorescent resonance energy transfe	Alexandrov I (1997), Koch HB (2007), Ivanov AA (2017)	3
YWHAB	1	YWHAG	5	affinity chromatography technology, biochemical	Couzens AL (2013), Wan C (2015)	2
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
PCK1	1	MAGED2	1	affinity chromatography technology	Jiang W (2011)	1
HSPA4	3	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
CEP250	4	CALU	4	affinity chromatography technology	Fogeron ML (2013)	1
PPP5C	2	YWHAQ	0	affinity chromatography technology	Yadav L (2017)	1
PPP2R1A	8	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Aranda-Orgilles B (2008), Gano JJ (2010)	2
PPP2R1A	8	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
CRK	0	HSPB1	2	biochemical	Havugimana PC (2012)	1
EGFR	5	RAF1	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PPP5C	2	HSPA4	3	affinity chromatography technology	Zeke T (2005)	1
HDAC5	4	EMD	0	affinity chromatography technology	Greco TM (2011)	1
RNF126	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Smith CJ (2013), Smith CJ (2013), Smith CJ (2013)	3
EGLN3	0	PIK3R2	3	affinity chromatography technology	Rodriguez J (2016)	1
TUBG1	2	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	GPRASP2	0	affinity chromatography technology	Bennett EJ (2010)	1
P4HA2	3	SAV1	0	affinity chromatography technology	Huttlin EL (2017)	1
HSP90AA1	7	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Hu Y (2003), Skarra DV (2011)	2
EGLN3	0	PPP5C	2	affinity chromatography technology	Rodriguez J (2016)	1
RIPK4	0	FKBP5	0	affinity chromatography technology	Rodriguez J (2016)	1
STAU1	1	IRS4	2	affinity chromatography technology	Milev MP (2012)	1
COPS5	0	PPP2R1A	8	genetic interference	Horlbeck MA (2018)	1
AURKB	2	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
TMEM216	0	WDR6	6	bioid	Gupta GD (2015)	1
IRS4	2	GBF1	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MAPK6	1	IRS4	2	affinity chromatography technology	Rodriguez J (2016)	1
LGR4	3	NISCH	11	affinity chromatography technology	Carmon KS (2014)	1
MTNR1A	1	IRS4	2	affinity chromatography technology, pull down	Daulat AM (2007), Benleulmi-Chaachoua A (2016)	2
YWHAQ	0	HSPB1	2	affinity chromatography technology, two hybrid	Pozuelo-Rubio M (2010), Katsogiannou M (2014)	2
CRK	0	PIK3R3	0	affinity chromatography technology, two hybrid	Brehme M (2009), Grossmann A (2015)	2
FKBP5	0	AURKB	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NDN	0	TP53	0	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Taniura H (1999), Taniura H (1999), Huang Z (2013), Corominas R (2014), Hasegawa K (2008), Hasegawa K (2008)	6
GRB2	2	YWHAZ	1	affinity chromatography technology	Bisson N (2011)	1
EGLN3	0	CLPB	3	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	YWHAZ	1	affinity chromatography technology	Rodriguez J (2016)	1
CCDC8	1	LGALS3BP	5	affinity chromatography technology	Hanson D (2014)	1
IRS4	2	BIN1	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
RAF1	3	EMD	0	affinity chromatography technology	So J (2015)	1
HDAC5	4	YWHAQ	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Vega RB (2004), Vega RB (2004), Ha CH (2010), Greco TM (2011), Xu C (2012), Joshi P (2013), Walkinshaw DR (2013)	7
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
IRS4	2	YWHAE	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
RAF1	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
NF2	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	PPP2R1A	8	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGLN3	0	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
NISCH	11	PIK3R1	6	affinity chromatography technology	Boldt K (2016)	1
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ZNF598	6	VCP	6	affinity chromatography technology	Garzia A (2017)	1
IRS4	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
YWHAB	1	PIK3R2	3	affinity chromatography technology	Jin J (2004)	1
MAGED2	1	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
DLD	1	HSPA4	3	affinity chromatography technology	Malty RH (2017)	1
YWHAQ	0	RAF1	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Ewing RM (2007), Yeung K (2000), Van Der Hoeven PC (2000), Liu YC (1996), Subramanian RR (2001), ONeill E (2004), Rajalingam K (2005), Zhu J (2005), Bonnefoy-Berard N (1995), So J (2015)	10
YWHAZ	1	RAF1	3	pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Clark GJ (1997), Tzivion G (2000), Tzivion G (2000), Koyama S (1995), Koyama S (1995), Van Der Hoeven PC (2000), Chow CW (2000), Andersen SD (2012), Subramanian RR (2001), Wang H (1998), Wang H (1998), Wang H (1998), Dougherty MK (2005), Rajalingam K (2005), Zhu J (2005), So J (2015), Powell DW (2003), Ivanov AA (2017)	18
EGLN3	0	HAUS2	2	affinity chromatography technology	Rodriguez J (2016)	1
MTNR1A	1	CUL3	17	two hybrid	Benleulmi-Chaachoua A (2016)	1
OTUB1	0	RNF126	2	two hybrid	Hayes SD (2012)	1
HDAC5	4	YWHAH	0	affinity chromatography technology, affinity chromatography technology	Greco TM (2011), Joshi P (2013)	2
MYC	2	BIN1	2	pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid	Elliott K (1999), Elliott K (1999), Pineda-Lucena A (2005), Pineda-Lucena A (2005), Pineda-Lucena A (2005), Pineda-Lucena A (2005)	6
AURKB	2	AURKA	1	affinity chromatography technology	Fogeron ML (2013)	1
MTNR1B	1	CUL3	17	two hybrid	Benleulmi-Chaachoua A (2016)	1
YWHAQ	0	YWHAH	0	affinity chromatography technology, biochemical, affinity chromatography technology	Pozuelo-Rubio M (2010), Kristensen AR (2012), Hein MY (2015)	3
EGFR	5	TUBB6	2	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
SIRT7	1	TUBB4A	3	affinity chromatography technology	Tsai YC (2012)	1
IRS4	2	100131997	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
DLD	1	YWHAH	0	affinity chromatography technology	Malty RH (2017)	1
IRS4	2	RCN1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL3	17	NISCH	11	affinity chromatography technology	Bennett EJ (2010)	1
LGALS3BP	5	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
TUBGCP3	1	MAGED2	1	affinity chromatography technology	Fogeron ML (2013)	1
SOCS6	0	IRS4	2	affinity chromatography technology	Krebs DL (2002)	1
CUL3	17	DNAJA3	2	affinity chromatography technology	Bennett EJ (2010)	1
PAN2	3	IRS4	2	affinity chromatography technology	Bett JS (2013)	1
PIK3R3	0	NISCH	11	affinity chromatography technology	Huttlin EL (2017)	1
PAN2	3	DNAJA2	2	affinity chromatography technology	Bett JS (2013)	1
IRS4	2	YWHAH	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	TUBB4A	3	affinity chromatography technology	Rodriguez J (2016)	1
MYC	2	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	CLPB	3	affinity chromatography technology	Bennett EJ (2010)	1
SOCS6	0	PIK3R1	6	affinity chromatography technology	Krebs DL (2002)	1
GRB2	2	NISCH	11	affinity chromatography technology	Bisson N (2011)	1
TUBG1	2	TUBGCP3	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Choi YK (2010), Choi YK (2010), Fogeron ML (2013), Fogeron ML (2013), Hein MY (2015)	5
SIRT7	1	COPS5	0	affinity chromatography technology	Mo Y (2017)	1
PTEN	24	PIK3R2	3	enzymatic study, affinity chromatography technology	He J (2010), He J (2010)	2
MAPK6	1	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
VCP	6	RCN1	0	biochemical	Wan C (2015)	1
MAPK6	1	PPP2R1A	8	two hybrid	Vinayagam A (2011)	1
RIPK4	0	DNAJA2	2	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	LGALS3BP	5	affinity chromatography technology	Bennett EJ (2010)	1
CCDC8	1	TUBB6	2	affinity chromatography technology	Hanson D (2014)	1
EGLN3	0	AURKA	1	affinity chromatography technology	Rodriguez J (2016)	1
GRB2	2	YWHAG	5	affinity chromatography technology	Bisson N (2011)	1
GRB2	2	YWHAB	1	affinity chromatography technology	Bisson N (2011)	1
YWHAE	0	TUBA1A	13	affinity chromatography technology	Gloeckner CJ (2007)	1
CEP250	4	TUBB4A	3	affinity chromatography technology	Fogeron ML (2013)	1
NF2	1	EGFR	5	affinity chromatography technology, fluorescent resonance energy transfe	Guerrero PA (2015), Ivanov AA (2017)	2
PDHA1	7	HSPB1	2	affinity chromatography technology	Malty RH (2017)	1
EGLN3	0	HSPA4	3	affinity chromatography technology	Rodriguez J (2016)	1
CEP76	1	CALU	4	affinity chromatography technology	Fogeron ML (2013)	1
PPEF1	1	DNAJA3	2	affinity chromatography technology	Yadav L (2017)	1
LGR4	3	IRS4	2	affinity chromatography technology	Carmon KS (2014)	1
PAN2	3	NISCH	11	affinity chromatography technology	Boldt K (2016)	1
TUBGCP3	1	RCN2	0	affinity chromatography technology	Fogeron ML (2013)	1
PAN2	3	HSP90AA1	7	affinity chromatography technology	Bett JS (2013)	1
YWHAZ	1	YWHAG	5	biochemical, biochemical, affinity chromatography technology, fluorescent resonance energy transfe	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Ivanov AA (2017)	4
EGLN3	0	USP9X	15	affinity chromatography technology	Rodriguez J (2016)	1
FBXO7	1	WDR6	6	affinity chromatography technology	Teixeira FR (2016)	1
AARSD1	0	IRS4	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
DUSP16	0	YWHAG	5	affinity chromatography technology	Yadav L (2017)	1
EGLN3	0	DNAJA2	2	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	RCN1	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
EGFR	5	PIK3R3	0	unspecified method, two hybrid, imaging technique, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014)	4
CUL2	3	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
IRS4	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Sano H (2002), Skarra DV (2011)	2
IRS4	2	FKBP5	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CFTR	5	YWHAE	0	affinity chromatography technology	Pankow S (2015)	1
PINK1	2	TUBA1A	13	affinity chromatography technology	Imai Y (2010)	1
CEP76	1	RCN1	0	affinity chromatography technology	Fogeron ML (2013)	1
DUSP16	0	DNAJA2	2	affinity chromatography technology	Yadav L (2017)	1
SIRT7	1	TP53	0	affinity chromatography technology	Tsai YC (2012)	1
CUL1	7	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
PPP2R1A	8	YWHAG	5	affinity chromatography technology	Yadav L (2017)	1
VCP	6	PPP2R1A	8	affinity chromatography technology, affinity chromatography technology	Ohama T (2010), Yakovlev VA (2013)	2
COPS5	0	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Cayli S (2009), Cayli S (2009), Cayli S (2009), Cayli S (2009), Bennett EJ (2010)	5
TP53	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Fraser JA (2010), Sun Y (2007), Wang J (2011), Horikawa I (2014), Horikawa I (2014), Kishor A (2013)	7
DLD	1	VCP	6	affinity chromatography technology	Malty RH (2017)	1
CCDC8	1	YWHAH	0	affinity chromatography technology	Hanson D (2014)	1
CEP57	0	HSP90AA1	7	affinity chromatography technology	Fogeron ML (2013)	1
HAUS2	2	TUBG1	2	affinity chromatography technology	Fogeron ML (2013)	1
YWHAE	0	YWHAQ	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Bandyopadhyay S (2010), Pozuelo-Rubio M (2010), Gloeckner CJ (2007), Wang J (2011)	4
IRS4	2	GPRASP2	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MYC	2	RCN1	0	affinity chromatography technology	Agrawal P (2010)	1
ERBB2	6	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Citri A (2002), Jung Y (2007), Suzuki T (2011)	3
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
PINK1	2	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Imai Y (2010), Moriwaki Y (2008)	2
SIRT7	1	STAU1	1	affinity chromatography technology	Tsai YC (2012)	1
YWHAQ	0	PIK3R2	3	pull down, affinity chromatography technology, affinity chromatography technology	Bonnefoy-Berard N (1995), Bonnefoy-Berard N (1995), Bonnefoy-Berard N (1995)	3
ILK	0	TUBB4A	3	affinity chromatography technology	So J (2015)	1
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
CFTR	5	DNAJA2	2	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
EGLN3	0	EMD	0	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	GRB2	2	affinity chromatography technology	Rodriguez J (2016)	1
PTEN	24	PINK1	2	affinity chromatography technology	Crockett DK (2005)	1
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
IRS4	2	DNAJA2	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
PDHA1	7	IRS4	2	affinity chromatography technology	Malty RH (2017)	1
TP53	0	PPP2R1A	8	imaging technique, affinity chromatography technology	Chen TC (2014), Kikuchi J (2003)	2
ZNF746	0	IRS4	2	affinity chromatography technology	Kang H (2015)	1
CEP76	1	HSP90AA1	7	affinity chromatography technology	Fogeron ML (2013)	1
HDAC5	4	TP53	0	affinity chromatography technology	Greco TM (2011)	1
CEP57	0	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
FBXO7	1	PPP2R1A	8	affinity chromatography technology	Teixeira FR (2016)	1
CFTR	5	TP53	0	affinity chromatography technology	Pankow S (2015)	1
SOCS6	0	SAV1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	YWHAE	0	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	CEP57	0	pull down	Miyamoto-Sato E (2010)	1
CUL1	7	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Oshikawa K (2003), Bennett EJ (2010)	2
CDKN1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology	Starostina NG (2010), Starostina NG (2010)	2
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
AARSD1	0	FBXO7	1	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	YWHAQ	0	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
FBXO7	1	DNAJA2	2	affinity chromatography technology	Teixeira FR (2016)	1
MYC	2	AKAP8L	1	affinity chromatography technology	Koch HB (2007)	1
IRS4	2	CTSB	5	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MTNR1B	1	YWHAB	1	two hybrid	Benleulmi-Chaachoua A (2016)	1
GRB2	2	PTPN18	1	affinity chromatography technology	Bisson N (2011)	1
RIPK4	0	PIK3R3	0	affinity chromatography technology	Rodriguez J (2016)	1
DLD	1	YWHAB	1	affinity chromatography technology	Malty RH (2017)	1
IRS4	2	MAGED2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Fogeron ML (2013)	3
CEP76	1	RCN2	0	affinity chromatography technology	Fogeron ML (2013)	1
ILK	0	MAGED1	0	affinity chromatography technology	Varjosalo M (2013)	1
FKBP5	0	ILK	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
TUBG1	2	LGALS3BP	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	3
CRK	0	TP53	0	two hybrid	Grossmann A (2015)	1
MAPK6	1	WDR6	6	affinity chromatography technology	Rodriguez J (2016)	1
RIPK4	0	PPP5C	2	affinity chromatography technology	Rodriguez J (2016)	1
TUBA1A	13	TUBB6	2	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
MAGED2	1	MAGED1	0	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	TUBB4A	3	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	TUBG1	2	affinity chromatography technology	Koch HB (2007)	1
PTEN	24	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DUSP16	0	RCN2	0	affinity chromatography technology	Yadav L (2017)	1
TP53	0	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
CEP250	4	TUBG1	2	affinity chromatography technology	Fogeron ML (2013)	1
MAGED1	0	HSPB1	2	affinity chromatography technology	Ewing RM (2007)	1
VCP	6	PIK3R2	3	affinity chromatography technology	Yu CC (2013)	1
DNAJA3	2	HSP90AA1	7	affinity chromatography technology	Chen CY (2013)	1
HSPB1	2	HSP90AA1	7	two hybrid	Katsogiannou M (2014)	1
YWHAB	1	IRS4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Taipale M (2014), Taipale M (2014)	3
CUL3	17	YWHAH	0	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	TUBB6	2	affinity chromatography technology	Rodriguez J (2016)	1
ILK	0	IRS4	2	affinity chromatography technology	Varjosalo M (2013)	1
VCP	6	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bennett EJ (2010), Besten Wd (2012)	3
HSPA4	3	DNAJA2	2	biochemical	Wan C (2015)	1
CCDC8	1	YWHAQ	0	affinity chromatography technology	Hanson D (2014)	1
CCDC8	1	EMD	0	affinity chromatography technology	Hanson D (2014)	1
HSP90AA1	7	PTGES3	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down	McLaughlin SH (2002), Mollapour M (2010), Kovacs JJ (2005), Giommarelli C (2010), Tsutsumi S (2012), Lee YT (2004), Schuelke JP (2010), Sarkar S (2012), Gano JJ (2010), Zelin E (2012), Obermann WM (1998), Wang J (2011), Weaver AJ (2000), Donze O (2001), Shimamura T (2012), Chan CT (2008), Chan CT (2008), Graumann K (2000), Martinez-Yamout MA (2006), Chadli A (2010), Woo SH (2009), Woo SH (2009), Woo SH (2009), Ni L (2010), Chadli A (2008), Picard D (2006), Wochnik GM (2004), Woodford MR (2016), Scholz GM (2001), McLaughlin SH (2006), Sun L (2012), Woodford MR (2016), Lepvrier E (2015)	33
TUBGCP3	1	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
EGFR	5	PTPN18	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
RAF1	3	YWHAB	1	two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuryev A (2003), Truong AB (2002), Van Der Hoeven PC (2000), Yuryev A (2000), Vincenz C (1996), Conklin DS (1995), Subramanian RR (2001), Rajalingam K (2005), Zhu J (2005), Couzens AL (2013), So J (2015)	11
NPHP4	10	CACYBP	0	bioid	Gupta GD (2015)	1
YWHAG	5	GBF1	4	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
TERF1	1	IRS4	2	affinity chromatography technology	Giannone RJ (2010)	1
TP53	0	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FKBP5	0	CACYBP	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HDAC5	4	HSP90AA1	7	affinity chromatography technology	Greco TM (2011)	1
CUL1	7	LGALS3BP	5	affinity chromatography technology	Bennett EJ (2010)	1
PIK3R3	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
ILK	0	DNAJA3	2	affinity chromatography technology	So J (2015)	1
MTMR11	2	DNAJA3	2	affinity chromatography technology	St-Denis N (2016)	1
COPS5	0	LGALS3BP	5	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	DNAJA2	2	affinity chromatography technology	Fogeron ML (2013)	1
DLD	1	YWHAE	0	affinity chromatography technology	Malty RH (2017)	1
DLD	1	DNAJA2	2	affinity chromatography technology	Malty RH (2017)	1
STAU1	1	YWHAZ	1	affinity chromatography technology	Milev MP (2012)	1
MAPK6	1	TUBA1A	13	two hybrid	Vinayagam A (2011)	1
HSPB1	2	YWHAE	0	two hybrid	Katsogiannou M (2014)	1
RIPK4	0	PIK3R1	6	affinity chromatography technology	Rodriguez J (2016)	1
SIRT7	1	PDHA1	7	affinity chromatography technology	Tsai YC (2012)	1
EGFR	5	CUL4B	8	affinity chromatography technology	Tong J (2014)	1
HSP90AA1	7	CACYBP	0	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Gano JJ (2010), Goral A (2016), Goral A (2016), Goral A (2016)	4
PIK3R1	6	ALK	8	pull down	Ren SY (2005)	1
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
HSP90AA1	7	LGALS3BP	5	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Fogeron ML (2013)	2
EGFR	5	GBF1	4	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Yao Z (2017)	2
USP9X	15	MAGED1	0	affinity chromatography technology	Agrawal P (2012)	1
EGLN3	0	TUBGCP3	1	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	NDN	0	two hybrid	Wijesuriya TM (2017)	1
ILK	0	TUBB6	2	affinity chromatography technology	So J (2015)	1
TMEM216	0	EMD	0	bioid	Gupta GD (2015)	1
EGLN3	0	ILK	0	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	MAGED2	1	affinity chromatography technology	Yao Z (2017)	1
SIRT7	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai YC (2012), Mo Y (2017), Mo Y (2017), Mo Y (2017)	4
CFTR	5	YWHAZ	1	affinity chromatography technology	Pankow S (2015)	1
CRK	0	DNAJA3	2	affinity chromatography technology	Brehme M (2009)	1
MYC	2	IRS4	2	affinity chromatography technology	Koch HB (2007)	1
CEP57	0	HSPB1	2	affinity chromatography technology	Fogeron ML (2013)	1
ZNF598	6	YWHAE	0	affinity chromatography technology	Garzia A (2017)	1
TERF2	2	CLPB	3	affinity chromatography technology	Giannone RJ (2010)	1
IRS4	2	EGFR	5	unspecified method, affinity chromatography technology	Jones RB (2006), Tong J (2014)	2
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
NF2	1	AKAP8L	1	affinity chromatography technology	Zhou L (2015)	1
CEP57	0	CCDC8	1	affinity chromatography technology	Fogeron ML (2013)	1
MYC	2	YWHAQ	0	affinity chromatography technology	Koch HB (2007)	1
COPS5	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
VCP	6	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Zhang Z (2015)	3
NF2	1	HSPA4	3	affinity chromatography technology	Hauri S (2013)	1
DERL1	2	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Dong Q (2017), Dong Q (2017)	2
VCP	6	YWHAQ	0	affinity chromatography technology	Yu CC (2013)	1
MAPK6	1	RNF126	2	affinity chromatography technology	Rodriguez J (2016)	1
PINK1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2010), Weihofen A (2008), Weihofen A (2008), Moriwaki Y (2008), Moriwaki Y (2008), Taipale M (2012), Ando M (2017)	7
SOCS6	0	TUBA1A	13	affinity chromatography technology	Krebs DL (2002)	1
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
PCK1	1	MAGED1	0	affinity chromatography technology	Jiang W (2011)	1
CRK	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
SIRT7	1	USP9X	15	affinity chromatography technology	Tsai YC (2012)	1
UBXN6	1	IRS4	2	affinity chromatography technology	Haines DS (2012)	1
CUL3	17	MAGED2	1	affinity chromatography technology	Bennett EJ (2010)	1
AARSD1	0	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	PPP2R1A	8	affinity chromatography technology	Rodriguez J (2016)	1
GRB2	2	DNAJA3	2	two hybrid	Wang J (2008)	1
PTGES3	0	CALU	4	biochemical	Wan C (2015)	1
CCDC8	1	YWHAG	5	affinity chromatography technology	Hanson D (2014)	1
IRS4	2	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fantin VR (1998), Bisson N (2011), Bisson N (2011)	3
GRB2	2	WDR6	6	affinity chromatography technology	Bisson N (2011)	1
CUL3	17	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Oshikawa K (2003), Bennett EJ (2010)	2
YWHAE	0	YWHAB	1	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Couzens AL (2013), Wan C (2015)	4
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
CFTR	5	EGFR	5	affinity chromatography technology	Pankow S (2015)	1
ERBB2	6	PIK3R3	0	unspecified method	Jones RB (2006)	1
YWHAH	0	TUBG1	2	affinity chromatography technology	Brajenovic M (2004)	1
MYC	2	YWHAB	1	affinity chromatography technology	Koch HB (2007)	1
HSPB1	2	YWHAZ	1	two hybrid	Katsogiannou M (2014)	1
IRS4	2	RAF1	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP250	4	MAGED1	0	affinity chromatography technology	Fogeron ML (2013)	1
PTPN18	1	IRS4	2	affinity chromatography technology	St-Denis N (2016)	1
CEP250	4	HSP90AA1	7	affinity chromatography technology	Fogeron ML (2013)	1
PIK3R2	3	PIK3R3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CFTR	5	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goldstein RF (2007), Goldstein RF (2007), Sun F (2008), Schmidt BZ (2009), Rosser MF (2008), Pankow S (2015)	6
YWHAZ	1	TUBG1	2	affinity chromatography technology	Brajenovic M (2004)	1
VCP	6	GBF1	4	affinity chromatography technology	Yu CC (2013)	1
RIPK4	0	YWHAB	1	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
GRB2	2	YWHAE	0	affinity chromatography technology	Bisson N (2011)	1
CUL1	7	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	RNF126	2	affinity chromatography technology	Rodriguez J (2016)	1
CRK	0	PIK3CA	8	affinity chromatography technology	Brehme M (2009)	1
DERL1	2	CACYBP	0	affinity chromatography technology	You H (2017)	1
HSPB1	2	YWHAB	1	two hybrid	Katsogiannou M (2014)	1
EGFR	5	PTGES3	0	affinity chromatography technology	Tong J (2014)	1
ILK	0	WDR6	6	affinity chromatography technology	Varjosalo M (2013)	1
CUL3	17	MAGED1	0	affinity chromatography technology	Bennett EJ (2010)	1
EGFR	5	NDN	0	protein complementation assay	Deribe YL (2009)	1
FBXO7	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Kirk R (2008), Hsu JM (2004), Hagens O (2006), Bennett EJ (2010), Hein MY (2015), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Reitsma JM (2017), Reitsma JM (2017)	11
PTEN	24	CRKL	1	affinity chromatography technology	Crockett DK (2005)	1
RAF1	3	YWHAE	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vincenz C (1996), Conklin DS (1995), Subramanian RR (2001), Gloeckner CJ (2007), Rajalingam K (2005), Zhu J (2005), Choudhary C (2009), Choudhary C (2009), So J (2015)	9
SOCS6	0	PIK3R2	3	affinity chromatography technology	Krebs DL (2002)	1
IRS4	2	NISCH	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sano H (2002), Sano H (2002), Taipale M (2014), Taipale M (2014)	4
PIK3R3	0	PIK3CA	8	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Mothe I (1997), Grossmann A (2015), Hein MY (2015), Huttlin EL (2017)	4
YWHAZ	1	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology	Waterman MJ (1998), Waterman MJ (1998), Gu YM (2006)	3
CEP250	4	HDAC5	4	affinity chromatography technology	Fogeron ML (2013)	1
HDAC5	4	LGALS3BP	5	affinity chromatography technology	Greco TM (2011)	1
CFTR	5	STAU1	1	affinity chromatography technology	Pankow S (2015)	1
AURKA	1	USP9X	15	affinity chromatography technology	Fogeron ML (2013)	1
PIK3R2	3	TUBB6	2	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	TUBG1	2	affinity chromatography technology	Tong J (2014)	1
SAV1	0	YWHAZ	1	affinity chromatography technology	Couzens AL (2013)	1
RIPK4	0	TUBB6	2	affinity chromatography technology	Rodriguez J (2016)	1
RAF1	3	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhu J (2005), Zhu J (2005), Zhu J (2005), da Rocha Dias S (2005)	4
CCDC8	1	PPP2R1A	8	affinity chromatography technology	Hanson D (2014)	1
HAUS2	2	HDAC5	4	affinity chromatography technology	Fogeron ML (2013)	1
YWHAB	1	YWHAH	0	affinity chromatography technology, biochemical, affinity chromatography technology	Couzens AL (2013), Wan C (2015), Hein MY (2015)	3
SIRT7	1	VCP	6	affinity chromatography technology	Tsai YC (2012)	1
STAU1	1	YWHAQ	0	affinity chromatography technology	Milev MP (2012)	1
TUBG1	2	CCDC8	1	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
TERF1	1	USP9X	15	affinity chromatography technology	Giannone RJ (2010)	1
HAUS2	2	RCN1	0	affinity chromatography technology	Fogeron ML (2013)	1
RCN1	0	PTGES3	0	biochemical	Wan C (2015)	1
CALU	4	AARSD1	0	biochemical	Kristensen AR (2012)	1
GRB2	2	LGALS3BP	5	affinity chromatography technology	Li J (2013)	1
YWHAB	1	GBF1	4	affinity chromatography technology	Couzens AL (2013)	1
ZNF598	6	USP9X	15	affinity chromatography technology	Garzia A (2017)	1
PINK1	2	IRS4	2	affinity chromatography technology	Imai Y (2010)	1
YWHAZ	1	YWHAH	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	4
HSP90AA1	7	DNAJA2	2	affinity chromatography technology, biochemical	Skarra DV (2011), Wan C (2015)	2
EGLN3	0	YWHAQ	0	affinity chromatography technology	Rodriguez J (2016)	1
YWHAG	5	RAF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Autieri MV (1999), Van Der Hoeven PC (2000), Rajalingam K (2005), Zhu J (2005), So J (2015), Ivanov AA (2017)	7
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	STAU1	1	affinity chromatography technology	Bennett EJ (2010)	1
MAPK6	1	HSPA4	3	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	ERBB2	6	unspecified method	Jones RB (2006)	1
YWHAQ	0	YWHAZ	1	affinity chromatography technology, biochemical, affinity chromatography technology	Pozuelo-Rubio M (2010), Kristensen AR (2012), Hein MY (2015)	3
PAN2	3	RCN2	0	affinity chromatography technology	Bett JS (2013)	1
SIRT7	1	IRS4	2	affinity chromatography technology	Tsai YC (2012)	1
EMD	0	TBL1XR1	23	affinity chromatography technology, affinity chromatography technology	Holaska JM (2007), Holaska JM (2007)	2
SOCS6	0	PIK3R3	0	affinity chromatography technology, two hybrid	Huttlin EL (2015), Grossmann A (2015)	2
HDAC5	4	PPP2R1A	8	affinity chromatography technology	Greco TM (2011)	1
ILK	0	RCN1	0	affinity chromatography technology	So J (2015)	1
AURKA	1	CALU	4	affinity chromatography technology	Hutchins JR (2010)	1
HAUS2	2	RCN2	0	affinity chromatography technology	Fogeron ML (2013)	1
MTMR11	2	IRS4	2	affinity chromatography technology	St-Denis N (2016)	1
RMND5A	0	LGALS3BP	5	affinity chromatography technology	Lampert F (2018)	1
RNF126	2	IRS4	2	affinity chromatography technology	OConnor HF (2015)	1
UBXN6	1	TUBB6	2	affinity chromatography technology	Haines DS (2012)	1
PTGES3	0	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schuelke JP (2010), Taipale M (2014), Taipale M (2014)	3
PAN2	3	TP53	0	affinity chromatography technology	Bett JS (2013)	1
PDHA1	7	DNAJA2	2	affinity chromatography technology	Malty RH (2017)	1
EGFR	5	TUBA1A	13	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
CUL3	17	GRB2	2	affinity chromatography technology	Bennett EJ (2010)	1
CFTR	5	TUBB6	2	affinity chromatography technology	Pankow S (2015)	1
CCDC8	1	YWHAE	0	affinity chromatography technology	Hanson D (2014)	1
TUBGCP3	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
YWHAQ	0	CEP250	4	affinity chromatography technology	Pozuelo-Rubio M (2010)	1
CUL2	3	AKAP8L	1	affinity chromatography technology	Bennett EJ (2010)	1
MTNR1A	1	YWHAZ	1	two hybrid	Benleulmi-Chaachoua A (2016)	1
IRS4	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
GPRASP2	0	CCDC8	1	affinity chromatography technology	Li S (2014)	1
ALK	8	IRS4	2	affinity chromatography technology	Crockett DK (2004)	1
IRS4	2	P4HA2	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
IRS4	2	TUBB6	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CUL2	3	EMD	0	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	NF2	1	affinity chromatography technology	Rodriguez J (2016)	1
HDAC5	4	HSPA4	3	affinity chromatography technology	Greco TM (2011)	1
CFTR	5	YWHAB	1	affinity chromatography technology	Pankow S (2015)	1
COPS5	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
NF2	1	DNAJA2	2	affinity chromatography technology	Hauri S (2013)	1
FBXO7	1	TUBB4A	3	affinity chromatography technology	Teixeira FR (2016)	1
ILK	0	RCN2	0	affinity chromatography technology	So J (2015)	1
CUL4B	8	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
MYC	2	DNAJA2	2	affinity chromatography technology	Koch HB (2007)	1
ZNF746	0	USP9X	15	affinity chromatography technology	Kang H (2015)	1
YWHAZ	1	YWHAE	0	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, biochemical, affinity chromatography technology, pull down	Bandyopadhyay S (2010), Zippo A (2009), Zippo A (2009), Havugimana PC (2012), Gloeckner CJ (2007), Wang J (2011), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Gu YM (2006)	10
CEP57	0	YWHAE	0	affinity chromatography technology	Fogeron ML (2013)	1
RIPK4	0	PTGES3	0	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	ILK	0	affinity chromatography technology	Bennett EJ (2010)	1
GPRASP2	0	RAF1	3	affinity chromatography technology	Li S (2014)	1
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
TMEM17	0	EMD	0	bioid	Gupta GD (2015)	1
EGLN3	0	OTUB1	0	affinity chromatography technology	Rodriguez J (2016)	1
CRKL	1	IRS4	2	pull down	Koval AP (1998)	1
TP53	0	AURKA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, genetic interference, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Katayama H (2004), Katayama H (2004), Katayama H (2004), Katayama H (2004), Hsueh KW (2013), Huttlin EL (2015), Huttlin EL (2017)	12
UBXN6	1	VCP	6	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kern M (2009), Kern M (2009), Kern M (2009), Stapf C (2011), Stapf C (2011), Stapf C (2011), Alexandru G (2008), Haenzelmann P (2011), Haenzelmann P (2011), Allen MD (2006), Nagahama M (2009), Nagahama M (2009), Alexandru G (2012), Haines DS (2012), Yu CC (2013), Huttlin EL (2015), Madsen L (2014), Trusch F (2015), Raman M (2015), Raman M (2015), Guo X (2017), Guo X (2017), Huttlin EL (2017)	23
CUL3	17	WDR6	6	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
CRK	0	YWHAG	5	affinity chromatography technology	Brehme M (2009)	1
CEP250	4	RCN1	0	affinity chromatography technology	Fogeron ML (2013)	1
COPS5	0	DNAJA2	2	affinity chromatography technology	Bennett EJ (2010)	1
CEP250	4	RCN2	0	affinity chromatography technology	Fogeron ML (2013)	1
MYC	2	P4HA1	1	affinity chromatography technology	Koch HB (2007)	1
EGLN3	0	RMND5A	0	affinity chromatography technology	Rodriguez J (2016)	1
PCK1	1	YWHAQ	0	affinity chromatography technology	Jiang W (2011)	1
AURKA	1	ZNF598	6	genetic interference	Horlbeck MA (2018)	1
IRS4	2	TBL1XR1	23	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
EMD	0	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
MYC	2	HSPB1	2	affinity chromatography technology, affinity chromatography technology	Koch HB (2007), Agrawal P (2010)	2
CFTR	5	PTGES3	0	affinity chromatography technology	Wang X (2006)	1
EGLN3	0	CCDC8	1	affinity chromatography technology	Rodriguez J (2016)	1
MAPK6	1	EMD	0	two hybrid	Vinayagam A (2011)	1
CUL3	17	PDHA1	7	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	DNAJA3	2	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	YWHAQ	0	affinity chromatography technology	Bennett EJ (2010)	1
TUBG1	2	MAGED2	1	affinity chromatography technology	Fogeron ML (2013)	1
ILK	0	EMD	0	affinity chromatography technology	So J (2015)	1
TERF2	2	HSPA4	3	affinity chromatography technology	Giannone RJ (2010)	1
CUL3	17	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
MAPK6	1	MAGED2	1	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	YWHAQ	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
HSP90AA1	7	ALK	8	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
CUL4B	8	TUBG1	2	affinity chromatography technology	Thirunavukarasou A (2015)	1
TUBG1	2	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
SAV1	0	TUBB6	2	affinity chromatography technology	Couzens AL (2013)	1
TP53	0	CCDC8	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dai C (2011), Dai C (2011), Dai C (2011), Dai C (2011), Fogeron ML (2013), Hanson D (2014), Hanson D (2014)	7
MAGED2	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Papageorgio C (2007), Fogeron ML (2013)	2
CUL1	7	ILK	0	affinity chromatography technology	Bennett EJ (2010)	1
VCP	6	TERF2	2	affinity chromatography technology	Yu CC (2013)	1
COPS5	0	ILK	0	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	TBL1XR1	23	affinity chromatography technology	Rodriguez J (2016)	1
DLD	1	PDHA1	7	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Malty RH (2017)	4
AURKA	1	SIRT7	1	affinity chromatography technology	Hein MY (2015)	1
DLD	1	YWHAG	5	affinity chromatography technology	Malty RH (2017)	1
TP53	0	TUBG1	2	affinity chromatography technology	Fogeron ML (2013)	1
OTUB1	0	MAGED2	1	affinity chromatography technology	Scholz CC (2016)	1
CUL3	17	YWHAE	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
VCP	6	RNF126	2	affinity chromatography technology	Yu CC (2013)	1
PPEF1	1	IRS4	2	affinity chromatography technology	Yadav L (2017)	1
EGLN3	0	IRS4	2	affinity chromatography technology	Rodriguez J (2016)	1
YWHAE	0	YWHAH	0	two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Bandyopadhyay S (2010), Gloeckner CJ (2007), Kristensen AR (2012), Wan C (2015), Hein MY (2015)	5
OTUB1	0	HSPA4	3	affinity chromatography technology	Scholz CC (2016)	1
GRB2	2	PPP5C	2	affinity chromatography technology	Bisson N (2011)	1
RIPK4	0	YWHAQ	0	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	P4HA1	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NF2	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CFTR	5	IRS4	2	affinity chromatography technology	Pankow S (2015)	1
CDKN1A	1	TUBA1A	13	two hybrid, affinity chromatography technology	Vinayagam A (2011), Fogeron ML (2013)	2
CUL4B	8	LGALS3BP	5	affinity chromatography technology	Bennett EJ (2010)	1
CEP250	4	CCDC8	1	affinity chromatography technology	Fogeron ML (2013)	1
TP53	0	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
DLD	1	OTUB1	0	affinity chromatography technology	Malty RH (2017)	1
MTMR11	2	TUBB6	2	affinity chromatography technology	St-Denis N (2016)	1
RAF1	3	PPP2R1A	8	affinity chromatography technology	Rajalingam K (2005)	1
VCP	6	PTGES3	0	biochemical	Wan C (2015)	1
MAPK6	1	HSPB1	2	affinity chromatography technology	Rodriguez J (2016)	1
VCP	6	YWHAB	1	affinity chromatography technology	Yu CC (2013)	1
IRS4	2	YWHAG	5	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MYC	2	YWHAE	0	affinity chromatography technology	Koch HB (2007)	1
CFTR	5	LGALS3BP	5	affinity chromatography technology	Pankow S (2015)	1
CUL2	3	LGALS3BP	5	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	SAV1	0	affinity chromatography technology	Rodriguez J (2016)	1
TERF2	2	TERF1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Giannone RJ (2010), Ye JZ (2004), Ye JZ (2004)	3
NF2	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TUBA1A	13	MYC	2	affinity chromatography technology	Conacci-Sorrell M (2010)	1
CALU	4	EGFR	5	biochemical	Havugimana PC (2012)	1
EGLN3	0	YWHAB	1	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	CLPB	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NPHP4	10	HSP90AA1	7	bioid	Gupta GD (2015)	1
CRK	0	YWHAQ	0	affinity chromatography technology	Brehme M (2009)	1
EGLN3	0	VCP	6	affinity chromatography technology	Rodriguez J (2016)	1
COPS5	0	HSPA4	3	affinity chromatography technology	Bennett EJ (2010)	1
EGFR	5	NPHP4	10	affinity chromatography technology	Yao Z (2017)	1
COX15	3	YWHAE	0	affinity chromatography technology	Malty RH (2017)	1
YWHAQ	0	YWHAB	1	affinity chromatography technology, affinity chromatography technology, biochemical	Pozuelo-Rubio M (2010), Couzens AL (2013), Kristensen AR (2012)	3
VCP	6	DERL1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography	Wang Q (2008), Ballar P (2007), Schulze A (2005), Schulze A (2005), Ye Y (2005), Lilley BN (2005), Greenblatt EJ (2011), Younger JM (2006), Christianson JC (2012), You H (2017), Lim JJ (2016), Lim JJ (2016)	12
DERL1	2	PPP2R1A	8	affinity chromatography technology	You H (2017)	1
TERF2	2	IRS4	2	affinity chromatography technology	Giannone RJ (2010)	1
CFTR	5	USP9X	15	affinity chromatography technology	Wang X (2006)	1
TP53	0	RCN2	0	affinity chromatography technology	Fogeron ML (2013)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
ZNF746	0	AKAP8L	1	affinity chromatography technology	Kang H (2015)	1
HDAC5	4	YWHAB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Grozinger CM (2000), Greco TM (2011), Joshi P (2013), Couzens AL (2013)	4
RC3H1	6	AKAP8L	1	affinity chromatography technology	Murakawa Y (2015)	1
CUL3	17	TUBA1A	13	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
CFTR	5	HSPB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahner A (2013), Wang X (2006), Gong X (2016), Pankow S (2015)	4
RAF1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016)	15
CEP76	1	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
ILK	0	HSPB1	2	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), So J (2015)	2
EGFR	5	TUBB4A	3	affinity chromatography technology	Foerster S (2013)	1
AURKB	2	HDAC5	4	affinity chromatography technology	Fogeron ML (2013)	1
DUSP16	0	TUBB6	2	affinity chromatography technology	Yadav L (2017)	1
DUSP16	0	IRS4	2	affinity chromatography technology	Yadav L (2017)	1
ZNF598	6	HSP90AA1	7	affinity chromatography technology	Garzia A (2017)	1
SAV1	0	IRS4	2	affinity chromatography technology	Couzens AL (2013)	1
RIPK4	0	GPRASP2	0	affinity chromatography technology	Rodriguez J (2016)	1
IRS4	2	PPP5C	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Taipale M (2014), Taipale M (2014), Yadav L (2017), Yadav L (2017)	4
LGALS3BP	5	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
TP53	0	OTUB1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Sun XX (2011), Sun XX (2011), Sun XX (2011), Li Y (2014), Fernandez-Majada V (2016)	5
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
YWHAB	1	TP53	0	affinity chromatography technology	Lee MK (2007)	1
MTNR1A	1	YWHAB	1	two hybrid	Benleulmi-Chaachoua A (2016)	1
EGFR	5	PPP5C	2	protein complementation assay	Deribe YL (2009)	1
MYC	2	DNAJA3	2	affinity chromatography technology	Koch HB (2007)	1
HSP90AA1	7	AURKB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	5
EGFR	5	WDR6	6	affinity chromatography technology	Tong J (2014)	1
YWHAE	0	RCN2	0	affinity chromatography technology	Zuo S (2010)	1
EMD	0	YWHAB	1	affinity chromatography technology	Holaska JM (2007)	1
MAGED2	1	FKBP5	0	biochemical	Kristensen AR (2012)	1
EGLN3	0	DNAJA3	2	affinity chromatography technology	Rodriguez J (2016)	1
AKAP8L	1	EMD	0	affinity chromatography technology	Martins SB (2000)	1
PHLPP1	4	IRS4	2	affinity chromatography technology	Gangula NR (2013)	1
MAPK6	1	MAGED1	0	affinity chromatography technology	Rodriguez J (2016)	1
HSP90AA1	7	SOCS6	0	affinity chromatography technology	Taipale M (2012)	1
AURKA	1	HSP90AA1	7	affinity chromatography technology	Fogeron ML (2013)	1
PHLPP1	4	FKBP5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), St-Denis N (2016), Luo K (2017), Luo K (2017)	4
PIK3CA	8	EGFR	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL4B	8	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
FKBP5	0	HSP90AA1	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Nair SC (1997), Nair SC (1997), Li J (2011), Schuelke JP (2010), Gano JJ (2010), Skarra DV (2011), Horibe T (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Graumann K (2000), Ni L (2010), Luo K (2017)	13
DLD	1	YWHAQ	0	affinity chromatography technology	Malty RH (2017)	1
IRS4	2	AKAP8L	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
GRB2	2	YWHAQ	0	affinity chromatography technology	Bisson N (2011)	1
DUSP16	0	PTGES3	0	affinity chromatography technology	Li X (2016)	1
VCP	6	HSPB1	2	affinity chromatography technology	Yu CC (2013)	1
FBXO7	1	CACYBP	0	enzymatic study	Teixeira FR (2016)	1
TMEM17	0	PIK3R1	6	bioid	Gupta GD (2015)	1
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
PTPN18	1	DNAJA2	2	affinity chromatography technology	St-Denis N (2016)	1
EGFR	5	DNAJA2	2	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
RIPK4	0	HSPB1	2	affinity chromatography technology	Rodriguez J (2016)	1
PAN2	3	EMD	0	affinity chromatography technology	Bett JS (2013)	1
RCN1	0	RNF41	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL3	17	SAV1	0	affinity chromatography technology	Bennett EJ (2010)	1
IRS4	2	DNAJA3	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
PTEN	24	HSP90AA1	7	affinity chromatography technology, genetic interference	Maddika S (2011), Shen JP (2017)	2
VCP	6	CALU	4	biochemical	Wan C (2015)	1
TP53	0	YWHAE	0	affinity chromatography technology	Fogeron ML (2013)	1
RIPK4	0	TUBB4A	3	affinity chromatography technology	Rodriguez J (2016)	1
ZNF746	0	MAGED2	1	affinity chromatography technology	Kang H (2015)	1
IRS4	2	DNAH17	20	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
AARSD1	0	HSPB1	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
MAPK6	1	AURKB	2	affinity chromatography technology	Rodriguez J (2016)	1
PCK1	1	IRS4	2	affinity chromatography technology	Jiang W (2011)	1
CUL3	17	TUBB6	2	affinity chromatography technology	Bennett EJ (2010)	1
PPEF1	1	CALU	4	affinity chromatography technology	Yadav L (2017)	1
EGFR	5	HSPB1	2	affinity chromatography technology	Li J (2013)	1
MAPK6	1	DNAJA2	2	affinity chromatography technology	Rodriguez J (2016)	1
RMND5A	0	CUL4B	8	affinity chromatography technology	Lampert F (2018)	1
IRS4	2	WDR6	6	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
CRK	0	IRS4	2	affinity chromatography technology, pull down	Karas M (2001), Koval AP (1998)	2
RC3H1	6	IRS4	2	affinity chromatography technology	Murakawa Y (2015)	1
PPEF1	1	CTSB	5	affinity chromatography technology	Yadav L (2017)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
VCP	6	YWHAZ	1	affinity chromatography technology, two hybrid	Yu CC (2013), Wang J (2011)	2
CFTR	5	P4HA1	1	affinity chromatography technology	Wang X (2006)	1
ILK	0	DNAJA2	2	affinity chromatography technology	So J (2015)	1
YWHAH	0	PIK3CA	8	affinity chromatography technology	Ichimura T (2002)	1
VCP	6	CDKN1A	1	affinity chromatography technology	Yu CC (2013)	1
IRS4	2	CALU	4	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
RIPK4	0	PPP2R1A	8	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	PIK3R3	0	affinity chromatography technology	Rodriguez J (2016)	1
CEP250	4	LGALS3BP	5	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Fogeron ML (2013)	2
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
CUL3	17	DNAJA2	2	affinity chromatography technology	Bennett EJ (2010)	1
TUBG1	2	AURKA	1	affinity chromatography technology, affinity chromatography technology	Molli PR (2010), Molli PR (2010)	2
PTPN18	1	TUBB6	2	affinity chromatography technology	St-Denis N (2016)	1
TP53	0	EGFR	5	genetic interference, genetic interference	Xie L (2013), Ye H (2016)	2
EMD	0	YWHAE	0	affinity chromatography technology	Holaska JM (2007)	1
STAU1	1	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Brendel C (2004), Milev MP (2012)	2
YWHAG	5	YWHAE	0	two hybrid, affinity chromatography technology, two hybrid, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Wang J (2011), Wan C (2015)	4
UBXN6	1	DERL1	2	pull down	Nagahama M (2009)	1
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
PIK3CA	8	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRB2	2	PIK3R3	0	affinity chromatography technology	Bisson N (2011)	1
RIPK4	0	CUL1	7	affinity chromatography technology	Rodriguez J (2016)	1
MAPK6	1	AKAP8L	1	affinity chromatography technology	Rodriguez J (2016)	1
FBXO7	1	GBF1	4	affinity chromatography technology	Hein MY (2015)	1
NDN	0	MAGEL2	6	bioid	Wijesuriya TM (2017)	1
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
OTUB1	0	CRKL	1	affinity chromatography technology	Scholz CC (2016)	1
TUBG1	2	HSP90AA1	7	biochemical, affinity chromatography technology, affinity chromatography technology	Wigley WC (1999), Fogeron ML (2013), Hein MY (2015)	3
GRB2	2	PIK3CA	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Bisson N (2011), Huttlin EL (2017)	3
VCP	6	IRS4	2	affinity chromatography technology	Fogeron ML (2013)	1
TMEM17	0	WDR6	6	bioid	Gupta GD (2015)	1
TUBGCP3	1	YWHAQ	0	affinity chromatography technology	Fogeron ML (2013)	1
COPS5	0	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
HDAC5	4	IRS4	2	affinity chromatography technology	Greco TM (2011)	1
RIPK4	0	EMD	0	affinity chromatography technology	Rodriguez J (2016)	1
DUSP16	0	HSPB1	2	affinity chromatography technology	Li X (2016)	1
TERF2	2	DNAJA2	2	affinity chromatography technology	Giannone RJ (2010)	1
PIK3R3	0	VCP	6	two hybrid	Grossmann A (2015)	1
PPP2R1A	8	YWHAB	1	affinity chromatography technology	Yadav L (2017)	1
MTNR1B	1	RNF41	2	two hybrid	Benleulmi-Chaachoua A (2016)	1
HSPA4	3	FKBP5	0	affinity chromatography technology	Schuelke JP (2010)	1
HSPB1	2	TP53	0	two hybrid, affinity chromatography technology, imaging technique	Stelzl U (2005), Sun Y (2007), Chen TC (2014)	3
TP53	0	AURKB	2	affinity chromatography technology	Wu L (2011)	1
PTEN	24	TUBA1A	13	genetic interference	Vizeacoumar FJ (2013)	1
CCDC8	1	IRS4	2	affinity chromatography technology	Hanson D (2014)	1
TERF1	1	HSPA4	3	affinity chromatography technology	Giannone RJ (2010)	1
OTUB1	0	AURKA	1	enzymatic study	Min M (2015)	1
COPS5	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Pick E (2012)	7
DLD	1	CACYBP	0	affinity chromatography technology	Malty RH (2017)	1
RIPK4	0	CLPB	3	affinity chromatography technology	Rodriguez J (2016)	1
GRB2	2	YWHAH	0	affinity chromatography technology	Bisson N (2011)	1
RIPK4	0	HSPA4	3	affinity chromatography technology	Rodriguez J (2016)	1
SAV1	0	YWHAH	0	affinity chromatography technology	Couzens AL (2013)	1
EGLN3	0	MAGED1	0	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	RAF1	3	affinity chromatography technology	Rodriguez J (2016)	1
PIK3R2	3	CRK	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Brehme M (2009), Grossmann A (2015)	3
CACYBP	0	RNF41	2	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
IRS4	2	RCN2	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
ILK	0	ZNF746	0	two hybrid	Vinayagam A (2011)	1
YWHAQ	0	TUBA1A	13	pull down	Meek SE (2004)	1
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
YWHAG	5	YWHAH	0	biochemical, biochemical, affinity chromatography technology	Kristensen AR (2012), Wan C (2015), Hein MY (2015)	3
MAPK6	1	HAUS2	2	two hybrid	Vinayagam A (2011)	1
RIPK4	0	YWHAH	0	affinity chromatography technology	Rodriguez J (2016)	1
SIRT7	1	HSPA4	3	affinity chromatography technology	Tsai YC (2012)	1
CUL3	17	USP9X	15	affinity chromatography technology	Bennett EJ (2010)	1
YWHAH	0	RAF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ichimura T (2002), Van Der Hoeven PC (2000), Vincenz C (1996), Subramanian RR (2001), Rajalingam K (2005), Zhu J (2005), So J (2015), Hein MY (2015), Hein MY (2015)	9