Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
ABCB11	8647	PROBUCOL	CHEMBL608	inhibitor	TTD
ABCB11	8647	GLYCOCHENODEOXYCHOLIC ACID	CHEMBL409348		GuideToPharmacologyInteractions
ABCB11	8647	CLOFAZIMINE	CHEMBL1292		DrugBank	12739759
ABCB11	8647	GLYBURIDE	CHEMBL472	inhibitor	DrugBank	15618715, 15465654, 12404239
ABCB11	8647	ADENOSINE TRIPHOSPHATE	CHEMBL14249		DrugBank	17126857, 16819395

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ABCB11	rs7579275	G	rosuvastatin	metabolism/PK	yes		Allele G is associated with increased exposure to rosuvastatin in healthy individuals as compared to allele A.	30100615	1449733115
ABCB11	rs2287622	G	rosuvastatin	metabolism/PK	yes	Alleles complemented to plus chromosomal strand.	Allele G is associated with increased exposure to rosuvastatin in healthy individuals as compared to allele A.	30100615	1449733121
ABCB11	rs4148776	G	glibenclamide	efficacy	yes	No allele was given for the association, so the minor allele from dbSNP at this location was used. Response to treatment was measured as fasting plasma glucose below 7 mmol/L change after 1-year of treatment.	Allele G is associated with increased response to glibenclamide in people with as compared to allele A.	27403931	1448123726
ABCB11	rs2287622	G	ceftriaxone	metabolism/PK	no	Please note that alleles have been complemented to the positive strand. No significant association was found between this variant and concentrations of ceftriaxone in the plasma or cerebrospinal fluid (CSF) of patients. There was also no significant association between this variant and ceftriaxone CSF to plasma ratios.	Allele G is not associated with concentrations of ceftriaxone in people with Central Nervous System Infections as compared to allele A.	29873816	1450044751