Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
NRP1	8829	PEGAPTANIB OCTASODIUM	CHEMBL2108752		TEND
NRP1	8829	PALIFERMIN	CHEMBL1201821		TdgClinicalTrial, DrugBank	10821861, 9890894, 9094999

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
NRP1	rs2229935	G	ranibizumab	efficacy	no	Response was measured as change in visual acuity after 3 months of treatment in patients who received three monthly ranibizumab injections.	Allele G is not associated with response to ranibizumab in people with Macular Degeneration as compared to allele A.	26426212	1446907760
NRP1	rs2070296	T	ranibizumab	efficacy	yes	Associated with change in visual acuity after 3 months of treatment in patients who received three monthly ranibizumab injections.	Allele T is associated with decreased response to ranibizumab in people with Macular Degeneration as compared to genotype CC.	26426212	1446907744
NRP1	rs2804495	G	ranibizumab	efficacy	no	Response was measured as change in visual acuity after 3 months of treatment in patients who received three monthly ranibizumab injections.	Allele G is not associated with response to ranibizumab in people with Macular Degeneration as compared to allele T.	26426212	1446907775
NRP1	rs2247383	G	ranibizumab	efficacy	no	Response was measured as change in visual acuity after 3 months of treatment in patients who received three monthly ranibizumab injections.	Allele G is not associated with response to ranibizumab in people with Macular Degeneration as compared to allele A.	26426212	1446907768