PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PPP1CC	2	PCNA	0	affinity chromatography technology	Flores-Delgado G (2007)	1
UBE2K	0	UHRF2	1	two hybrid	Markson G (2009)	1
CDC5L	2	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
GADD45A	1	GADD45B	1	affinity chromatography technology	Kovalsky O (2001)	1
XPO1	8	RPTOR	4	affinity chromatography technology	Kirli K (2015)	1
CDT1	2	GRWD1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2015), Sugimoto N (2015), Sugimoto N (2015)	6
PRKN	1	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Sarraf SA (2013), Huttlin EL (2017)	3
CDK2	0	SET	8	affinity chromatography technology	Neganova I (2011)	1
CDKN1A	1	HDAC1	4	pull down, affinity chromatography technology, pull down, imaging technique	Li Z (2010), Li Z (2010), Garcia-Wilson E (2005), Chen TC (2014)	4
BRCA1	7	CAND1	2	affinity chromatography technology	Ertych N (2016)	1
USP37	1	BRCA1	7	bioid	Yeh C (2015)	1
PCNA	0	DNMT1	5	affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rountree MR (2000), Iida T (2002), Chuang LS (1997), Ha K (2011), Pichler G (2012), Pichler G (2012), Pichler G (2012), Hervouet E (2010), Hervouet E (2010), Cai Y (2014), Han J (2014), Hein MY (2015)	12
CCNB1	3	FXR1	0	affinity chromatography technology	Hein MY (2015)	1
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
SNW1	0	PPP1CA	3	affinity chromatography technology	Lleres D (2010)	1
CCNB1	3	NDC80	4	biochemical	Havugimana PC (2012)	1
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
RELA	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Zhong H (2002), Zhong H (2002), Zhong H (2002), Zhong H (2002), Ashburner BP (2001), Ashburner BP (2001), OShea JM (2010), OShea JM (2010), Liu Y (2006), Cao W (2006), Hu J (2004), Hu J (2004), Sun JM (2007), Deckmann K (2012)	15
XPO1	8	TP73	2	unspecified method	Xu D (2012)	1
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
CCNB2	3	TSPYL2	4	affinity chromatography technology	Li Y (2008)	1
MARCH5	0	UBE2D2	0	pull down, pull down, pull down	Yonashiro R (2012), Yonashiro R (2009), Sugiura A (2013)	3
GAS2L1	2	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
FOXM1	3	PRC1	4	affinity chromatography technology	Li X (2015)	1
CDC14A	4	CDC6	0	enzymatic study	Bremmer SC (2012)	1
CNTRL	5	CCNB1	3	bioid	Gupta GD (2015)	1
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
CDC25B	4	CDK5	0	affinity chromatography technology, enzymatic study	Vincent I (2001), Chang KH (2012)	2
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
CAND1	2	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
DCTN1	6	NDC80	4	bioid	Gupta GD (2015)	1
CCNB1	3	HIST1H1B	4	enzymatic study, enzymatic study	Vazquez-Novelle MD (2010), Poon RY (1996)	2
CCNB1	3	CDC6	0	enzymatic study	Jiang W (1999)	1
USP14	1	XPO1	8	biochemical	Havugimana PC (2012)	1
CDC5L	2	CDC16	2	affinity chromatography technology	Lleres D (2010)	1
CAND1	2	GAPDH	0	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	CDC25B	4	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uchida S (2011), Uchida S (2011), Kanemori Y (2005), Kim TY (2014), Coyaud E (2015), Loveless TB (2015), Coyaud E (2015), Hein MY (2015), St-Denis N (2016), Huttlin EL (2017)	10
CKS2	0	PKMYT1	1	affinity chromatography technology	Huttlin EL (2017)	1
XPO1	8	ANAPC10	0	affinity chromatography technology	Kirli K (2015)	1
BRCA1	7	XIAP	0	affinity chromatography technology, pull down	Martin SA (2005), Martin SA (2005)	2
USP37	1	CDT1	2	affinity chromatography technology	Hernandez-Perez S (2016)	1
BTRC	1	PCM1	5	bioid	Coyaud E (2015)	1
PRDX1	1	PRDX3	3	biochemical	Wan C (2015)	1
CCNB1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Di Fiore B (2010), Nishiyama A (2000), Wolthuis R (2008), Desai D (1995), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
PCNA	0	CDK5	0	affinity chromatography technology, affinity chromatography technology	Takasaki Y (2001), Wu SM (1998)	2
RB1	2	TRAP1	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Chen CF (1996), Chen CF (1996), Chen CF (1996), Chen CF (1996)	4
HDAC1	4	RALBP1	2	affinity chromatography technology	Hein MY (2015)	1
CDC25A	2	CDK3	0	affinity chromatography technology	Li X (2016)	1
CCAR1	7	PCNA	0	biochemical	Wan C (2015)	1
CCNB1	3	UBE3C	5	pull down, enzymatic study	Okada M (2015), Okada M (2015)	2
CDC25C	0	CDK1	0	pull down, affinity chromatography technology	Morris MC (2000), St-Denis N (2016)	2
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
BRCA1	7	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu Y (2012), Lu Y (2012), Parameswaran B (2015)	3
SPICE1	2	CCNB1	3	bioid	Gupta GD (2015)	1
CCDC6	3	CCNB1	3	affinity chromatography technology	Morra F (2015)	1
CCNB1	3	AKR7A2	1	affinity chromatography technology	Hein MY (2015)	1
ANAPC11	0	UBE2D2	0	affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Chang TS (2004), Townsend K (2009), Van Voorhis VA (2014), ODonovan KJ (2010), Tang Z (2001), Tang Z (2001), Vodermaier HC (2003), Shoji S (2014), Brown NG (2014), Brown NG (2015)	10
CCNB1	3	EP300	36	pull down, affinity chromatography technology	Felzien LK (1998), Felzien LK (1998)	2
CDKN1A	1	OTUB1	0	two hybrid	Vinayagam A (2011)	1
CCNB1	3	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
PRDX1	1	GAPDH	0	two hybrid, biochemical	Stelzl U (2005), Wan C (2015)	2
CDC25A	2	XPO1	8	two hybrid	Wang J (2011)	1
CDKN1A	1	HIST1H1B	4	enzymatic study	Poon RY (1996)	1
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
CKS1B	0	CCNB2	3	pull down, affinity chromatography technology	Radulovic M (2010), Huttlin EL (2017)	2
FZR1	1	UBE2K	0	pull down	Jin L (2008)	1
FZR1	1	CDC25A	2	affinity chromatography technology, pull down, enzymatic study	Gao D (2009), Donzelli M (2002), Donzelli M (2002)	3
VCP	6	PSMA6	1	affinity chromatography technology	Lim PJ (2009)	1
RALBP1	2	CCDC6	3	affinity chromatography technology	Huttlin EL (2017)	1
CDT1	2	CDC5L	2	pull down	Ramachandran N (2004)	1
CCNB1	3	TARSL2	1	affinity chromatography technology	Hein MY (2015)	1
CDKN1B	1	XPO1	8	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ishida N (2002), Connor MK (2003), Connor MK (2003), Connor MK (2003), Qiu H (2016)	5
VCP	6	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li JM (2013), Riemer A (2014), Zhang Z (2015)	3
CDC25A	2	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Galaktionov K (1991), Li X (2016)	2
CDK7	0	CDK2	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Drapkin R (1996), Cheng A (2005), Xu X (1999), Higashi H (1996), Aprelikova O (1995), Moisan A (2004), Larochelle S (2012), Larochelle S (2006), Larochelle S (2006), Garrett S (2001), Garrett S (2001), Lolli G (2004), Varjosalo M (2013), So J (2015)	14
CEP170	4	CCDC6	3	affinity chromatography technology	Huttlin EL (2015)	1
PPP1CC	2	VCP	6	affinity chromatography technology, affinity chromatography technology	Cid C (2007), Cid C (2007)	2
CDC6	0	UBE2K	0	two hybrid	Wang J (2011)	1
BRCA1	7	STAU1	1	affinity chromatography technology	Ertych N (2016)	1
CDKN1A	1	CKS2	0	affinity chromatography technology	Fogeron ML (2013)	1
FOXM1	3	KIF22	1	affinity chromatography technology	Li X (2015)	1
BRCA1	7	GAPDH	0	affinity chromatography technology	Ertych N (2016)	1
CNTRL	5	CEP170	4	bioid	Gupta GD (2015)	1
FZR1	1	E2F3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ping Z (2012), Ping Z (2012), Ping Z (2012)	3
PPP1CA	3	CEP170	4	two hybrid	Esteves SL (2012)	1
CCNB1	3	SDHAF2	1	biochemical	Havugimana PC (2012)	1
CDC16	2	CCNB1	3	affinity chromatography technology	van Zon W (2010)	1
PPP1CA	3	CDK2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
GAPDH	0	EP300	36	affinity chromatography technology, affinity chromatography technology	Sen N (2008), Sen N (2008)	2
PPP1CA	3	PPP1CB	9	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	6
CDK2	0	PPP1CB	9	affinity chromatography technology	Hein MY (2015)	1
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
ZADH2	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CEP162	3	CEP170	4	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
SNW1	0	PARVA	0	affinity chromatography technology	Lleres D (2010)	1
VCP	6	CDKN1B	1	affinity chromatography technology	Yu CC (2013)	1
KIF22	1	CCNB1	3	affinity chromatography technology	Hein MY (2015)	1
XPO1	8	FOXO1	2	affinity chromatography technology	Kirli K (2015)	1
BRCA1	7	CDC16	2	affinity chromatography technology	Hill SJ (2014)	1
SKP2	2	OFD1	3	affinity chromatography technology	Huttlin EL (2017)	1
HDAC1	4	PPP1CC	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Gao J (2009), Brush MH (2004), Canettieri G (2003), Canettieri G (2003)	4
SKP2	2	CCNB1	3	affinity chromatography technology	Bashir T (2010)	1
CCNB1	3	ANAPC10	0	affinity chromatography technology	Voets E (2015)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
PPP1CB	9	CCNB1	3	affinity chromatography technology	Flores-Delgado G (2007)	1
PCM1	5	DIAPH3	7	bioid	Gupta GD (2015)	1
PTMA	2	PCNA	0	biochemical	Freire J (2001)	1
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
SNW1	0	NCBP1	7	affinity chromatography technology	Lleres D (2010)	1
XPO1	8	CDC20	1	affinity chromatography technology	Kirli K (2015)	1
RPA1	0	GAPDH	0	affinity chromatography technology	Marechal A (2014)	1
CEP128	1	CEP170	4	bioid	Gupta GD (2015)	1
PPP1CC	2	CDK2	0	affinity chromatography technology	Flores-Delgado G (2007)	1
BRCA1	7	RELA	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Benezra M (2003), Benezra M (2003), Benezra M (2003), Volcic M (2012)	4
CDT1	2	CDC6	0	pull down, pull down, imaging technique	Sugimoto N (2008), Ramachandran N (2004), Sugimoto N (2015)	3
CCNB1	3	CKS2	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Radulovic M (2010), Hein MY (2015), Huttlin EL (2017)	4
CDK1	0	CCNB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
CDC25B	4	CDK1	0	affinity chromatography technology, affinity chromatography technology	Vincent I (2001), Zhong Y (2017)	2
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
CCNB1	3	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Amador V (2007), Garcia-Wilson E (2005), Ando T (2001), Poon RY (1996), Fogeron ML (2013), Chen TC (2014)	6
LRRFIP1	6	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
PTPDC1	3	CCNB1	3	affinity chromatography technology	Li X (2016)	1
CCNB1	3	PCNA	0	affinity chromatography technology, affinity chromatography technology	Zhang H (1993), Huttlin EL (2017)	2
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
FZR1	1	USP37	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2011), Huang X (2011), Saxena N (2014), Huttlin EL (2017)	4
SP1	0	CDK1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Yang HC (2014), Yang HC (2014)	6
CCNB1	3	KAT6A	19	affinity chromatography technology	Hein MY (2015)	1
SET	8	TRIM28	1	affinity chromatography technology	Kalousi A (2015)	1
HDAC1	4	TRIM28	1	affinity chromatography technology, affinity chromatography technology, biochemical	Allouch A (2011), Chen L (2012), Kristensen AR (2012)	3
CAND1	2	PDCD6	2	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	UBE2K	0	two hybrid, x-ray crystallography, pull down, two hybrid, pull down, pull down	Christensen DE (2009), Christensen DE (2009), Christensen DE (2009), Christensen DE (2007), David Y (2011), Shabbeer S (2013)	6
CDK1	0	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Zhan Q (1999), Horton LE (1997), Pan ZQ (1993), Pan ZQ (1993), Yarden RI (2002), Golsteyn RM (1995), Jiang W (1998), Badea T (2002), Bae Y (2013), Linares JF (2011), Sasaki T (2008), Chen M (2012), Tang J (2008)	13
CDC16	2	EP300	36	affinity chromatography technology	Turnell AS (2005)	1
RPA1	0	TRIM28	1	affinity chromatography technology	Marechal A (2014)	1
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
KEAP1	0	XPO1	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaspar JW (2012), Kaspar JW (2012), Kirli K (2015)	3
CCNB1	3	RPS3	0	affinity chromatography technology	Hein MY (2015)	1
PPP1CB	9	BRCA1	7	affinity chromatography technology, pull down	Winter SL (2007), Winter SL (2007)	2
CDK2	0	HIST1H1A	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Jeon Y (2007), Lunn CL (2010), Kiviharju-af Haellstroem TM (2007), Kim YB (2000), Xu X (1999), Mori S (1999), Lauper N (1998), Lauper N (1998), Orend G (1998), Wu G (1997), Horton LE (1997), Higashi H (1996), Musgrove EA (1996), Pan ZQ (1993), Pan ZQ (1993), Poon RY (1993), Sueoka N (1999), Baldassarre G (2000), Bendjennat M (2003), Liu S (2009), Sarmento LM (2005), Aprelikova O (1995), Giono LE (2007), Liu Y (2004), Dynlacht BD (1997), Mandal M (1998), Chang TS (2003), Colas P (1996), Jiang W (1998), Ezhevsky SA (1997), Thomas DM (2004), Song MS (2011), Naderi S (1999), Akagi M (1996), Lee B (2006), Grimmler M (2007), Zhang WN (2013), Iyer NG (2007), Morris L (2000), Chen M (2012), Guidoboni M (2005), Ghiani C (2001)	42
SP1	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Esteve PO (2007), Esteve PO (2007)	2
CDC14A	4	CDC25B	4	affinity chromatography technology, enzymatic study	Vazquez-Novelle MD (2010), Vazquez-Novelle MD (2010)	2
EP300	36	HIST1H1A	0	enzymatic study, enzymatic study	Loven MA (2004), Sakaguchi K (1998)	2
CDC25B	4	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
USP37	1	CDC16	2	bioid	Yeh C (2015)	1
CDKN1A	1	FOXO1	2	imaging technique	Chen TC (2014)	1
BTRC	1	GADD45A	1	affinity chromatography technology	Li D (2015)	1
USP37	1	CCNB1	3	affinity chromatography technology	Huang X (2011)	1
KEAP1	0	CCNB1IP1	0	two hybrid	Rolland T (2014)	1
BRCA1	7	UBE2D2	0	two hybrid, two hybrid, x-ray crystallography, pull down	Dynek JN (2010), Christensen DE (2009), Christensen DE (2009), Christensen DE (2009)	4
FZR1	1	PRKN	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
CDC5L	2	RPS3	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SPICE1	2	DIAPH3	7	bioid	Gupta GD (2015)	1
CEP162	3	CCNB1	3	bioid	Gupta GD (2015)	1
USP37	1	RPA1	0	bioid	Yeh C (2015)	1
CDC20	1	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nilsson J (2008), Voets E (2015), Kelly A (2014), Craney A (2016)	4
USP37	1	CDC20	1	affinity chromatography technology	Huang X (2011)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK1	0	SIRT1	3	enzymatic study, affinity chromatography technology	Sasaki T (2008), Sasaki T (2008)	2
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
XPO1	8	RPS18	1	affinity chromatography technology	Kirli K (2015)	1
CCNB1	3	HNRNPLL	1	biochemical	Wan C (2015)	1
CDC20	1	CDC16	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kallio MJ (2002), Kallio M (1998), Nilsson J (2008), Hutchins JR (2010), Fogeron ML (2013), Hein JB (2014), Hein MY (2015), Kelly A (2014), Craney A (2016), Listovsky T (2013), Qiao R (2016), Izawa D (2012)	12
CDC6	0	CDK2	0	affinity chromatography technology, enzymatic study	Saha P (1998), Jiang W (1999)	2
CDT1	2	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Senga T (2006), Hu J (2006), Arias EE (2006), Nishitani H (2006), Tsanov N (2014), Chandrasekaran S (2011), Coleman KE (2015), Higa LA (2006)	11
TRIM28	1	PPP1CA	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique	Li X (2010), Li X (2010), Li X (2010), Li X (2010), Li X (2010)	5
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
CDK7	0	HIST1H1A	0	enzymatic study	Drapkin R (1996)	1
BRCA1	7	XPO1	8	affinity chromatography technology	Ertych N (2016)	1
ANAPC10	0	ANAPC4	0	biochemical, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Voets E (2015)	8
SPICE1	2	PCM1	5	affinity chromatography technology, bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Huttlin EL (2017)	4
CCNB1	3	STK38	0	affinity chromatography technology	Lin Z (2015)	1
CDC25B	4	CCNB1	3	affinity chromatography technology	Li X (2016)	1
CCNB1	3	RPS18	1	affinity chromatography technology	Lin Z (2015)	1
CDKN1A	1	CDK5	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013)	4
SIRT1	3	RB1	2	affinity chromatography technology	Wang C (2006)	1
ANAPC11	0	UBE2K	0	pull down, pull down, pull down	Bassermann F (2008), Rodrigo-Brenni MC (2007), Van Voorhis VA (2014)	3
GADD45G	0	CDKN1A	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Azam N (2001), Azam N (2001), Azam N (2001), Nakayama K (1999)	4
POLA1	0	PCNA	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
FZR1	1	ZC3HC1	1	enzymatic study, affinity chromatography technology	von Klitzing C (2011), von Klitzing C (2011)	2
CDC20	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Huttlin EL (2017)	3
TRAP1	0	CCNB1	3	affinity chromatography technology	Sisinni L (2017)	1
PPP1CB	9	TRIM28	1	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Li X (2010), Li X (2010), Li X (2010), Li X (2010)	4
CDK3	0	CKS2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RB1	2	CDC27	2	affinity chromatography technology, biochemical, two hybrid, pull down	Binne UK (2007), Binne UK (2007), Chen PL (1995), Chen PL (1995)	4
PCNA	0	PRDX3	3	affinity chromatography technology	Hein MY (2015)	1
VCP	6	RPS3	0	affinity chromatography technology	Fogeron ML (2013)	1
MGMT	1	CDKN1A	1	affinity chromatography technology	Niture SK (2005)	1
STAU1	1	RPS3	0	affinity chromatography technology	Milev MP (2012)	1
LLGL2	4	CCNB1	3	affinity chromatography technology	Hein MY (2015)	1
SIRT1	3	DNMT1	5	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Peng L (2011), Peng L (2011), Peng L (2011), OHagan HM (2011), OHagan HM (2011)	5
GADD45A	1	CCNB1	3	pull down	Vairapandi M (2002)	1
CKS2	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
SP1	0	RELA	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuang PP (2002), Sif S (1994), Sif S (1994), Kao YS (2008), Kao YS (2008), Benjamin JT (2010), Beauchef G (2012), Xu Y (2008)	8
XPO1	8	CDC25B	4	affinity chromatography technology	Kirli K (2015)	1
PPP1CA	3	CDK1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
CCNB2	3	CDK7	0	biochemical	Wan C (2015)	1
STAU1	1	GAPDH	0	affinity chromatography technology	Milev MP (2012)	1
OFD1	3	CCNB1	3	bioid	Gupta GD (2015)	1
CDC20	1	PCNA	0	affinity chromatography technology	Craney A (2016)	1
CEP170	4	NIN	4	affinity chromatography technology, bioid, affinity chromatography technology	Huttlin EL (2015), Gupta GD (2015), Huttlin EL (2017)	3
CKS2	0	CCNB2	3	pull down, affinity chromatography technology	Radulovic M (2010), Huttlin EL (2017)	2
SNW1	0	CDK1	0	affinity chromatography technology	Lleres D (2010)	1
BTRC	1	RPS18	1	bioid	Coyaud E (2015)	1
CDKN1A	1	SET	8	pull down, pull down	Canela N (2003), Carujo S (2006)	2
CDC20	1	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Mansfeld J (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Wolthuis R (2008), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Fogeron ML (2013), Hein JB (2014), Hein JB (2014), Voets E (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Izawa D (2012), Izawa D (2012), Izawa D (2012), Izawa D (2012), Salsi V (2016)	25
KAT6A	19	EP300	36	affinity chromatography technology	Rokudai S (2009)	1
CCNB1	3	GRWD1	3	affinity chromatography technology	Lin Z (2015)	1
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
RPTOR	4	EP300	36	affinity chromatography technology	Wan W (2017)	1
CEP162	3	OFD1	3	affinity chromatography technology, affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
FZR1	1	ANAPC10	0	unspecified method	Vodermaier HC (2003)	1
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
CDK3	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDKN1B	1	CDK5	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Kabuta T (2013), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	7
CCDC6	3	PPP1CA	3	imaging technique	Leone V (2010)	1
UBE2D2	0	RELA	1	enzymatic study	Ryo A (2003)	1
PCM1	5	CEP170	4	affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	3
NIN	4	CCNB2	3	bioid	Gupta GD (2015)	1
CEP128	1	CCNB2	3	bioid	Gupta GD (2015)	1
MGMT	1	CCNB1	3	affinity chromatography technology	Niture SK (2005)	1
CDK2	0	RPS3	0	affinity chromatography technology	Neganova I (2011)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
SIRT1	3	CCNB1	3	affinity chromatography technology	Sasaki T (2008)	1
CDC20	1	USP22	1	affinity chromatography technology	Lin Z (2015)	1
PPP1CA	3	CCNB1	3	affinity chromatography technology	Flores-Delgado G (2007)	1
CDK7	0	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
CDC5L	2	GAPDH	0	affinity chromatography technology	Lleres D (2010)	1
TRAP1	0	GAPDH	0	biochemical, biochemical	Matassa DS (2013), Wan C (2015)	2
PCNA	0	AKR7A2	1	affinity chromatography technology	Hein MY (2015)	1
SNW1	0	DIAPH3	7	affinity chromatography technology	Lleres D (2010)	1
CDC6	0	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
PRKN	1	HERC5	2	affinity chromatography technology, affinity chromatography technology	Im E (2016), Im E (2016)	2
CCNB1	3	DIAPH3	7	biochemical	Wan C (2015)	1
HDAC1	4	UHRF2	1	affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Unoki M (2004), Unoki M (2004), Mori T (2011), Zeng S (2017), Zeng S (2017), Lai M (2016)	6
CEP128	1	PCM1	5	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
MGMT	1	CDK2	0	affinity chromatography technology	Niture SK (2005)	1
VCP	6	PDCD6	2	affinity chromatography technology	Yu CC (2013)	1
PPP1CA	3	RB1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Flores-Delgado G (2007), Dunaief JL (2002), Durfee T (1993), Durfee T (1993), Durfee T (1993), Guo C (2007)	6
EP300	36	PRKDC	12	pull down	Karmakar S (2010)	1
CDC27	2	ANAPC10	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Lara-Gonzalez P (2011), Dube P (2005), Fehr AR (2012), Holzmann J (2011), Kurasawa Y (1999), Kurasawa Y (1999), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015)	13
XPO1	8	RELA	1	affinity chromatography technology	Kirli K (2015)	1
CEP128	1	SPICE1	2	bioid	Gupta GD (2015)	1
CAND1	2	FBF1	2	affinity chromatography technology	Bennett EJ (2010)	1
STAU1	1	TRIM28	1	affinity chromatography technology	Milev MP (2012)	1
CCNB1	3	PTCH1	8	affinity chromatography technology	Barnes EA (2005)	1
SNW1	0	TRAP1	0	affinity chromatography technology	Lleres D (2010)	1
EP300	36	FOXO1	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Brent MM (2008), Perrot V (2005), Perrot V (2005), Perrot V (2005), Perrot V (2005), Pramanik KC (2014), Pramanik KC (2014), Mahmud DL (2002), Li X (2015)	9
CCNB1	3	SQSTM1	0	pull down	Linares JF (2011)	1
TP53BP1	3	ANAPC4	0	affinity chromatography technology	Woods NT (2012)	1
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
CDK1	0	PKMYT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	4
CDC25C	0	CCNB1	3	pull down	Morris MC (2000)	1
XPO1	8	DIAPH3	7	affinity chromatography technology	Kirli K (2015)	1
CEP128	1	CCNB1	3	bioid	Gupta GD (2015)	1
CCNB1	3	TP53BP1	3	enzymatic study	van Vugt MA (2010)	1
PCM1	5	NDC80	4	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
TGFBR2	0	CCNB1	3	pull down	Liu JH (1999)	1
PSMA6	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Cohen-Kaplan V (2016), Cohen-Kaplan V (2016), Cohen-Kaplan V (2016)	3
CCNB1	3	CCNB2	3	biochemical	Wan C (2015)	1
GADD45G	0	CCNB1	3	pull down	Vairapandi M (2002)	1
OFD1	3	NDC80	4	bioid	Gupta GD (2015)	1
SP1	0	CCNB1	3	imaging technique, affinity chromatography technology, affinity chromatography technology	Chuang JY (2012), Chuang JY (2012), Yang HC (2014)	3
SET	8	CCNB1	3	affinity chromatography technology	Carujo S (2006)	1
UBE2K	0	CCNB1	3	affinity chromatography technology	Bae Y (2010)	1
SET	8	HIST1H1A	0	affinity chromatography technology	Kato K (2011)	1
CDT1	2	CCNB1	3	affinity chromatography technology, pull down	Sugimoto N (2004), Sugimoto N (2004)	2
MFN1	6	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Park YY (2012), Park YY (2012)	2
USP37	1	CDC27	2	affinity chromatography technology, bioid	Huang X (2011), Yeh C (2015)	2
TP53BP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Matsuoka S (2007), Wang B (2002), Bohgaki T (2011), Ertych N (2016)	4
BTRC	1	KEAP1	0	affinity chromatography technology, bioid	Sowa ME (2009), Coyaud E (2015)	2
TRIM28	1	UBE2D2	0	pull down	Doyle JM (2010)	1
CDK2	0	DNMT1	5	affinity chromatography technology	Hein MY (2015)	1
KEAP1	0	BRCA1	7	affinity chromatography technology	Ma J (2012)	1
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
CAND1	2	RPS18	1	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	TP53BP1	3	enzymatic study, enzymatic study	van Vugt MA (2010), Benada J (2015)	2
CDK1	0	CCNF	2	affinity chromatography technology	Kong M (2000)	1
CCDC6	3	CDK1	0	affinity chromatography technology	Morra F (2015)	1
BRCA1	7	VCP	6	affinity chromatography technology, pull down, affinity chromatography technology	Zhang H (2000), Zhang H (2000), Ertych N (2016)	3
IKZF5	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
NIN	4	PCM1	5	bioid	Gupta GD (2015)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
GRWD1	3	CDC6	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Sugimoto N (2015), Sugimoto N (2015), Sugimoto N (2015), Sugimoto N (2015)	4
CCNB1	3	TSPYL2	4	affinity chromatography technology, pull down	Li Y (2008), Li Y (2008)	2
CDK2	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koundrioukoff S (2000), Zhang H (1993), Neganova I (2011), Wu SM (1998), Chen Z (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
XPO1	8	CEP170	4	affinity chromatography technology	Kirli K (2015)	1
OFD1	3	USP22	1	bioid	Gupta GD (2015)	1
CDC27	2	FOXM1	3	affinity chromatography technology	Park HJ (2008)	1
TP73	2	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Satija YK (2016), Satija YK (2016), Satija YK (2016), Satija YK (2016)	4
SIRT1	3	RELA	1	affinity chromatography technology	Yang SR (2007)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC20	1	RPS3	0	affinity chromatography technology	Fogeron ML (2013)	1
CCNB1	3	ALKBH8	5	affinity chromatography technology	Hein MY (2015)	1
STAU1	1	PPP1CA	3	affinity chromatography technology, two hybrid, two hybrid	Brendel C (2004), Esteves SL (2012), Colland F (2004)	3
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
HIST1H1A	0	RPS3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	RPA1	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Suhasini AN (2011), Mok MT (2010), Tian F (2013)	3
UHRF2	1	CDK2	0	far western blotting, affinity chromatography technology, enzymatic study	Mori T (2011), Li Y (2004), Li Y (2004)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
BRCA1	7	RPS3	0	affinity chromatography technology	Ertych N (2016)	1
FZR1	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
ESPL1	2	CCNB1	3	affinity chromatography technology	Voets E (2015)	1
CAND1	2	FXR1	0	affinity chromatography technology	Bennett EJ (2010)	1
MGMT	1	PRKDC	12	affinity chromatography technology	Niture SK (2005)	1
BTRC	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	2
CDK2	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Fogeron ML (2013)	2
XPO1	8	SQSTM1	0	affinity chromatography technology	Kirli K (2015)	1
IKZF5	0	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
NGB	0	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
UBE2D2	0	CCNB1	3	enzymatic study	Tang Z (2001)	1
PRKDC	12	SP1	0	enzymatic study	Gottlieb TM (1993)	1
BRCA1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2003), Maor S (2007), Maor S (2007), Abramovitch S (2003)	4
OFD1	3	NIN	4	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
USP22	1	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lin Z (2012), Lin Z (2012), Armour SM (2013), Armour SM (2013), Armour SM (2013), Armour SM (2013), Wang Q (2016), Xiong H (2017), Xiong H (2017), Ling S (2017)	11
UBE3C	5	UBE2D2	0	pull down, pull down	Wu PY (2003), Kristariyanto YA (2015)	2
CDK1	0	PRC1	4	enzymatic study	Jiang W (1998)	1
CCNB1	3	PRKDC	12	affinity chromatography technology, pull down	Shang ZF (2015), Shang ZF (2015)	2
RPTOR	4	CCNB1	3	affinity chromatography technology	Gwinn DM (2010)	1
XPO1	8	ESPL1	2	affinity chromatography technology	Kirli K (2015)	1
GAS2L1	2	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC4	0	CDC16	2	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Ma HT (2011), Havugimana PC (2012), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Masuda K (2015), Boekhout M (2015), Huttlin EL (2017)	14
CEP128	1	CEP162	3	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CCNB1	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015)	2
CCNB1	3	SLC27A2	2	affinity chromatography technology	Hein MY (2015)	1
CAND1	2	TRIM28	1	affinity chromatography technology	Bennett EJ (2010)	1
DNMT1	5	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Zhang J (2011), Lai M (2016)	2
CCNB1	3	CDK7	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Garrett S (2001), Huttlin EL (2015), Huttlin EL (2017)	3
ARID4A	3	CDK2	0	enzymatic study	Suryadinata R (2011)	1
HERC5	2	STK38	0	pull down	Takeuchi T (2006)	1
DCTN1	6	CCNB1	3	bioid	Gupta GD (2015)	1
PTCH1	8	BTRC	1	affinity chromatography technology	Yamaki Y (2016)	1
CDK5	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2017)	3
SNW1	0	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
HNRNPLL	1	CCNB2	3	biochemical	Wan C (2015)	1
VCP	6	CDK1	0	affinity chromatography technology	Yu CC (2013)	1
CCNB1	3	STAU1	1	affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015)	2
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
RPA1	0	PRDX1	1	affinity chromatography technology	Marechal A (2014)	1
CCNB1	3	PRDX1	1	affinity chromatography technology	Hein MY (2015)	1
SIRT1	3	RPTOR	4	affinity chromatography technology, affinity chromatography technology	Back JH (2011), Back JH (2011)	2
PPP1CC	2	CCNB1	3	affinity chromatography technology	Flores-Delgado G (2007)	1
RALBP1	2	CCNB1	3	two hybrid, pull down, affinity chromatography technology	Rosse C (2003), Rosse C (2003), Rosse C (2003)	3
CCNB1	3	CCAR1	7	affinity chromatography technology	Lin Z (2015)	1
NIN	4	DCTN1	6	bioid	Gupta GD (2015)	1
CCNB2	3	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ramachandran N (2004), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
STAU1	1	CDC5L	2	affinity chromatography technology	Milev MP (2012)	1
CDC16	2	NCBP1	7	genetic interference	Horlbeck MA (2018)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
HDAC1	4	E2F3	0	affinity chromatography technology	Chen L (2012)	1
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
UHRF2	1	PCNA	0	far western blotting, x-ray crystallography, unspecified method, affinity chromatography technology	Mori T (2011), Chen W (2017), Chen W (2017), Lai M (2016)	4
RPA1	0	POLA1	0	affinity chromatography technology	Marechal A (2014)	1
CDK1	0	XIAP	0	enzymatic study	Hou Y (2017)	1
VCP	6	FBF1	2	affinity chromatography technology	Fogeron ML (2013)	1
RB1	2	HDAC1	4	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fuks F (2000), Puri PL (2001), Puri PL (2001), Wang S (2002), Luo RX (1998), Luo RX (1998), Lai A (1999), Lai A (1999), Ferreira R (1998), Kimura H (2003), Qiu Z (2008), Fedele M (2006), Brown VD (2002), Khan MM (2001), Dasgupta P (2004), Chang YC (2001), Dahiya A (2000), Zhang HS (2000), Tokitou F (1999), Nguyen DX (2004), Takaki T (2004), Magnaghi-Jaulin L (1998), Magnaghi-Jaulin L (1998), Brehm A (1998), Brehm A (1998), Brehm A (1998), Sun JM (2007), Fan LX (2012), Harbour JW (1999), Brehm A (1999), Joshi P (2013), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	36
CKS2	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
BRCA1	7	HDAC1	4	pull down	Yarden RI (1999)	1
CDK2	0	GAPDH	0	affinity chromatography technology	Neganova I (2011)	1
DCTN1	6	PRC1	4	bioid	Gupta GD (2015)	1
CDKN1B	1	HIST1H1B	4	enzymatic study	McAndrew CW (2007)	1
BRCA1	7	KIF22	1	affinity chromatography technology	Hill SJ (2014)	1
CDC16	2	ESPL1	2	affinity chromatography technology	Huttlin EL (2017)	1
SP1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singh J (2002), Chang YC (2001), Opitz OG (2000)	3
BRCA1	7	LRRFIP1	6	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	CCNB1	3	pull down, affinity chromatography technology, enzymatic study	Wang H (1997), Shabbeer S (2013), Shabbeer S (2013)	3
CDK1	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Major ML (2004)	2
PRDX3	3	XIAP	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC20	1	STAU1	1	affinity chromatography technology, affinity chromatography technology	Boulay K (2014), Boulay K (2014)	2
CDC5L	2	CDKN1A	1	pull down	Ramachandran N (2004)	1
CCNF	2	CDC6	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Walter D (2016), Walter D (2016), Walter D (2016), Walter D (2016)	4
FZR1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhou Y (2003), Kramer ER (1998), Farhana L (2002), Cen B (2010), Sorensen CS (2001), Binne UK (2007), Wang X (2008), Tran K (2008), Wang LY (2012), Wang LY (2012), Ban KH (2007), Lv XB (2010), Huang KT (2012), Song MS (2011), Fukushima H (2013), Lau AW (2013), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Choi BH (2014), Jeganathan KB (2006), Fang G (1998), Sedgwick GG (2012), Kelly A (2014), Listovsky T (2013), Pavlides SC (2016), Huttlin EL (2017)	28
SNW1	0	CCNB1	3	affinity chromatography technology	Lleres D (2010)	1
PRKN	1	SET	8	affinity chromatography technology	Zanon A (2013)	1
CDK2	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	McAndrew CW (2007), Hale TK (2006), Deep G (2006), Cheng A (2005), Alexandrow MG (2005), Nishimura T (2005), Du J (2004), Matsumoto Y (2004), Kehn K (2004), Harwell RM (2004), Shen WH (2004), Contreras A (2003), Porter LA (2002), Esashi F (2005), Dehde S (2001)	15
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
PSMA6	1	CCNF	2	affinity chromatography technology	Sharma SS (2011)	1
EP300	36	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kimbrel EA (2009), Kimbrel EA (2009)	2
CDC25C	0	CCNB2	3	affinity chromatography technology	St-Denis N (2016)	1
GAS2L1	2	LRRFIP1	6	affinity chromatography technology	Huttlin EL (2017)	1
ARID4A	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai A (2001), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	4
PCNA	0	RPA1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Ogi T (2010), Takasaki Y (2001), Gong Z (2011), Miccoli L (2005), Han J (2014)	6
XIAP	0	CKS1B	0	two hybrid	Rolland T (2014)	1
EP300	36	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hong R (2003), Hong R (2003), Cazzalini O (2008), Cazzalini O (2008), Naryzhny SN (2004), Cazzalini O (2014), Cazzalini O (2014)	10
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
CDK1	0	CKS2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Varjosalo M (2013), Radulovic M (2010), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
TRIM28	1	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Cui S (2011)	2
BTRC	1	OFD1	3	bioid	Coyaud E (2015)	1
CDK3	0	CDT1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SNW1	0	PRKDC	12	affinity chromatography technology	Lleres D (2010)	1
ANAPC4	0	FZR1	1	biochemical, biochemical, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Boekhout M (2015), Huttlin EL (2017)	6
FZR1	1	ANAPC11	0	affinity chromatography technology, pull down, unspecified method	Bassermann F (2008), Vodermaier HC (2003), Vodermaier HC (2003)	3
CCNB2	3	PKMYT1	1	affinity chromatography technology	Hein MY (2015)	1
CEP128	1	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
BRCA1	7	PSMA6	1	two hybrid	Woods NT (2012)	1
CDK1	0	SQSTM1	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Linares JF (2011), Linares JF (2011), Linares JF (2011), Galindo-Moreno M (2017)	4
CKS1B	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
SNW1	0	DCTN1	6	affinity chromatography technology	Lleres D (2010)	1
CCNB1	3	HIST1H1A	0	enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study	Zhan Q (1999), Sharma SS (2011), Pan ZQ (1993), Yarden RI (2002), Jiang W (1998)	5
CAND1	2	NCBP1	7	affinity chromatography technology	Bennett EJ (2010)	1
RPA1	0	CDC5L	2	affinity chromatography technology, pull down, affinity chromatography technology	Marechal A (2014), Marechal A (2014), Lleres D (2010)	3
ANAPC4	0	CDK1	0	affinity chromatography technology	Voets E (2015)	1
BTRC	1	SP1	0	pull down	Wei S (2009)	1
CDC5L	2	CCNB1	3	affinity chromatography technology	Lleres D (2010)	1
CCNB1	3	PRDX3	3	affinity chromatography technology	Hein MY (2015)	1
PRKDC	12	FZR1	1	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
EP300	36	MGMT	1	affinity chromatography technology	Teo AK (2001)	1
CKS1B	0	CDC27	2	pull down	Di Fiore B (2010)	1
FOXO1	2	SIRT1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kitamura YI (2005), Bastien-Dionne PO (2011), Yang Y (2005), Yang Y (2005)	4
UBE2D2	0	BTRC	1	enzymatic study	Cenciarelli C (1999)	1
CCNB1	3	PRC1	4	enzymatic study	Jiang W (1998)	1
EP300	36	SNW1	0	pull down	Leong GM (2004)	1
MARCH5	0	MFN1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park YY (2010), Park YY (2012), Park YY (2014), Park YY (2014)	4
CDK2	0	PRDX3	3	affinity chromatography technology	Neganova I (2011)	1
PSMA6	1	CDK2	0	affinity chromatography technology, affinity chromatography technology	Sharma SS (2011), Neganova I (2011)	2
PTMA	2	HDAC1	4	pull down	Knight JS (2003)	1
SNW1	0	HNRNPLL	1	affinity chromatography technology	Lleres D (2010)	1
CDC6	0	CDC20	1	pull down	Ke PY (2004)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
TP73	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Katayama H (2012), Katayama H (2012)	2
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
CEP162	3	RPA1	0	affinity chromatography technology	Gupta GD (2015)	1
CNTRL	5	NIN	4	bioid	Gupta GD (2015)	1
CCNB2	3	DIAPH3	7	biochemical	Wan C (2015)	1
CDC20	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
ANAPC11	0	CDC16	2	biochemical	Lu L (2013)	1
OTUB1	0	UBE2D2	0	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Nakada S (2010), Juang YC (2012), Ernst A (2013), Juang YC (2012), Huttlin EL (2015), Scholz CC (2016), Huttlin EL (2017)	8
CCNB1	3	PKMYT1	1	affinity chromatography technology	Hein MY (2015)	1
PCNA	0	PRKDC	12	affinity chromatography technology	Ohta S (2002)	1
SIRT1	3	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Lin Z (2012), Lin YH (2015), Lin YH (2015), Lin YH (2015)	4
SIRT1	3	SNW1	0	two hybrid, pull down, affinity chromatography technology	Kang MR (2010), Kang MR (2010), Kang MR (2010)	3
OFD1	3	PCM1	5	affinity chromatography technology, affinity chromatography technology, bioid, bioid, affinity chromatography technology	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Hein MY (2015)	5
PTMA	2	SET	8	affinity chromatography technology, affinity chromatography technology	Karetsou Z (2004), Karetsou Z (2004)	2
HERC5	2	CDKN1A	1	pull down	Mitsui K (1999)	1
PTMA	2	HIST1H1A	0	affinity chromatography technology	Cotter MA (2000)	1
RB1	2	SNW1	0	pull down, pull down	Prathapam T (2002), Prathapam T (2002)	2
ARID4A	3	CDK1	0	enzymatic study	Suryadinata R (2011)	1
XPO1	8	PTPDC1	3	affinity chromatography technology	Kirli K (2015)	1
CCNB2	3	CDKN1A	1	pull down	Ramachandran N (2004)	1
CCNB1	3	POLA1	0	enzymatic study	Dehde S (2001)	1
PPP1CA	3	BRCA1	7	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Winter SL (2007), Liu Y (2002), Liu Y (2002), Liu Y (2002), Liu Y (2002), Woods NT (2012), Chen BY (2014)	7
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
BRCA1	7	TRIM28	1	affinity chromatography technology	Ertych N (2016)	1
KEAP1	0	SQSTM1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Jain A (2010), Jain A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Inami Y (2011), Fan W (2010), Copple IM (2010), Copple IM (2010), Wright T (2013), Tanji K (2013), Ichimura Y (2013), Ichimura Y (2013), Ichimura Y (2013), Hast BE (2014), Hast BE (2014), Lerner C (2013), Rolland T (2014), Gjyshi O (2015), Bakkar N (2015), Milan E (2015), Park S (2016), Ge W (2017), Mildenberger J (2017), Lu K (2017), Lee Y (2017)	30
CDT1	2	CDC20	1	pull down	Sugimoto N (2008)	1
SNW1	0	CAND1	2	affinity chromatography technology	Lleres D (2010)	1
PTMA	2	EP300	36	genetic interference, pull down, affinity chromatography technology, pull down	Subramanian C (2002), Subramanian C (2002), Cotter MA (2000), Cotter MA (2000)	4
TP53BP1	3	RPA1	0	affinity chromatography technology, affinity chromatography technology	Yoo E (2005), Yoo E (2005)	2
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
GAPDH	0	CCNB1	3	pull down, affinity chromatography technology	Carujo S (2006), Carujo S (2006)	2
CDC25A	2	CDK2	0	pull down, enzymatic study, affinity chromatography technology	Xu X (1996), Cheng A (2005), Li X (2016)	3
NDC80	4	KLC3	3	two hybrid	Rolland T (2014)	1
CDC27	2	CDC16	2	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Ollendorff V (1997), Kallio M (1998), Gmachl M (2000), Kraft C (2003), Li Y (1997), Lara-Gonzalez P (2011), Binne UK (2007), van Zon W (2010), Dube P (2005), Holzmann J (2011), Hayes MJ (2006), Tugendreich S (1995), Havugimana PC (2012), Vodermaier HC (2003), Wan C (2015), Hein MY (2015), Kelly A (2014), Listovsky T (2013), Qiao R (2016), Huttlin EL (2017), Boldt K (2016)	22
E2F3	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inoue Y (2007), Moberg K (1996), Ianari A (2009), Lees JA (1993)	4
CCNB1	3	CDKN1B	1	affinity chromatography technology	Hein MY (2015)	1
CCNB1	3	DNMT1	5	affinity chromatography technology	Lin Z (2015)	1
PPP1CA	3	SKP2	2	affinity chromatography technology	Liu X (2016)	1
TP53BP1	3	ANAPC10	0	affinity chromatography technology	Woods NT (2012)	1
CDK2	0	TSPYL2	4	enzymatic study	Chai Z (2001)	1
STAU1	1	PRKDC	12	affinity chromatography technology	Milev MP (2012)	1
GADD45G	0	CDK1	0	pull down	Vairapandi M (2002)	1
CDC25B	4	CDK3	0	affinity chromatography technology	Li X (2016)	1
TRIM28	1	PPP1CC	2	affinity chromatography technology, affinity chromatography technology	Li X (2010), Li X (2010)	2
CDK2	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Luescher-Firzlaff JM (2006)	2
CDC5L	2	PPP1CA	3	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
CNTRL	5	PCM1	5	bioid	Gupta GD (2015)	1
ARID4A	3	CCNB1	3	enzymatic study	Suryadinata R (2011)	1
SPICE1	2	OFD1	3	bioid, affinity chromatography technology	Gupta GD (2015), Hein MY (2015)	2
CDK5	0	CCNB1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	5
USP37	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, bioid, affinity chromatography technology	Burrows AC (2012), Burrows AC (2012), Burrows AC (2012), Saxena N (2014), Yeh C (2015), Huttlin EL (2017)	6
MGMT	1	SET	8	affinity chromatography technology	Niture SK (2005)	1
CEP170	4	XIAP	0	bioid	Gupta GD (2015)	1
CDC5L	2	PARVA	0	affinity chromatography technology	Lleres D (2010)	1
CDC27	2	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Mansfeld J (2011), Lara-Gonzalez P (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Ma HT (2011), Ma HT (2011), Dube P (2005), Holzmann J (2011), Wolthuis R (2008), Havugimana PC (2012), Uzunova K (2012), Song MS (2011), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Tran K (2010), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Voets E (2015), Masuda K (2015), Boekhout M (2015), Craney A (2016), Qiao R (2016), Izawa D (2012), Hein JB (2016)	34
HERC5	2	CCNB1	3	pull down	Mitsui K (1999)	1
XPO1	8	CCDC6	3	affinity chromatography technology	Kirli K (2015)	1
PCM1	5	CCNB1	3	bioid	Gupta GD (2015)	1
HDAC1	4	TP73	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004), Uramoto H (2004), Zhang J (2007)	4
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
FBF1	2	PCM1	5	bioid	Gupta GD (2015)	1
ANAPC10	0	CDC16	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Kurasawa Y (1999), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	4
PTMA	2	CCNB1	3	biochemical	Freire J (2001)	1
CDK1	0	TRAP1	0	imaging technique, affinity chromatography technology	Sisinni L (2017), Sisinni L (2017)	2
CCNB1	3	PDCD6	2	affinity chromatography technology	Hein MY (2015)	1
CEP170	4	DCTN1	6	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
CAND1	2	STAU1	1	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	CAND1	2	affinity chromatography technology	Neganova I (2011)	1
MARCH5	0	CCNB1	3	affinity chromatography technology	Park YY (2012)	1
PRKN	1	CDK5	0	affinity chromatography technology, enzymatic study	Avraham E (2007), Avraham E (2007)	2
PCNA	0	GADD45A	1	two hybrid, far western blotting, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Smith ML (1994), Chen IT (1995), Vairapandi M (2000), Hall PA (1995), Hall PA (1995), Yang Q (2000), Smith ML (1994), Vairapandi M (2000), Smith ML (1994), Yang Q (2000), Vairapandi M (2000), Vairapandi M (2000), Kim HL (2013), Sanchez R (2010)	14
CDK5	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang J (2012), Cataldo F (2013), Maestre C (2008), Maestre C (2008)	4
XPO1	8	CCNB1	3	affinity chromatography technology	Kirli K (2015)	1
PPP1CC	2	CDK1	0	affinity chromatography technology	Flores-Delgado G (2007)	1
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
RPS3	0	RELA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Wan F (2007), Wan F (2007), Yang HJ (2013), Yang HJ (2013)	4
CDC20	1	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
EP300	36	TP53BP1	3	affinity chromatography technology	Jung SY (2005)	1
CAND1	2	GRWD1	3	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	SP1	0	enzymatic study	Fojas de Borja P (2001)	1
ZC3HC1	1	CCNB1	3	pull down, affinity chromatography technology, enzymatic study, enzymatic study	Bassermann F (2007), Bassermann F (2005), Bassermann F (2005), Liu YQ (2015)	4
XPO1	8	NCBP1	7	affinity chromatography technology	Kirli K (2015)	1
UBE2D2	0	XIAP	0	two hybrid, two hybrid, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down	Markson G (2009), Dynek JN (2010), Nakatani Y (2012), Nakatani Y (2012), Markson G (2009), Fang S (2001), Hu S (2003), Buetow L (2015), Foglizzo M (2016), Edison N (2017)	10
FZR1	1	FOXM1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park HJ (2008), Myatt SS (2013), Laoukili J (2008), Laoukili J (2008)	4
BRCA1	7	CDC25C	0	enzymatic study	Shabbeer S (2013)	1
CDK2	0	RPA1	0	enzymatic study	Pan ZQ (1993)	1
GAPDH	0	SET	8	pull down, affinity chromatography technology	Carujo S (2006), Carujo S (2006)	2
KLC3	3	CCNB1	3	affinity chromatography technology	Hein MY (2015)	1
CDC27	2	ANAPC11	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Dube P (2005), Lu L (2013), Gmachl M (2000), Vodermaier HC (2003), Craney A (2016)	8
RELA	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Spencer E (1999), Spencer E (1999), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	5
IKZF5	0	CKS1B	0	affinity chromatography technology	Huttlin EL (2017)	1
OFD1	3	CEP170	4	bioid	Gupta GD (2015)	1
PRKN	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, imaging technique	Sarraf SA (2013), Song P (2016), Song P (2016), Song P (2016), Song P (2016), Hou XO (2015), Geisler S (2014)	7
CCNF	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Choudhury R (2016), Choudhury R (2016), Choudhury R (2016)	3
VCP	6	TP53BP1	3	affinity chromatography technology	Yu CC (2013)	1
SIRT1	3	TP73	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Dai JM (2007), Dai JM (2007), Dai JM (2007)	3
CEP162	3	SPICE1	2	affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	4
EP300	36	CDT1	2	enzymatic study	Glozak MA (2009)	1
SNW1	0	CDK3	0	affinity chromatography technology	Lleres D (2010)	1
FOXO1	2	RB1	2	affinity chromatography technology	Li X (2015)	1
BTRC	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	4
PTCH1	8	PSMA6	1	affinity chromatography technology	Yamaki Y (2016)	1
CCNB1	3	USP22	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Lin Z (2015), Lin Z (2015), Lin Z (2015), Lin Z (2015)	4
XPO1	8	ANAPC4	0	affinity chromatography technology	Kirli K (2015)	1
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
XPO1	8	CDT1	2	affinity chromatography technology	Kirli K (2015)	1
PRKN	1	RPTOR	4	affinity chromatography technology	Park D (2014)	1
BRCA1	7	DNMT1	5	affinity chromatography technology	Hill SJ (2014)	1
CDC14A	4	SPICE1	2	bioid	St-Denis N (2016)	1
SET	8	TSPYL2	4	affinity chromatography technology	Huttlin EL (2017)	1
PTCH1	8	TRIM28	1	affinity chromatography technology	Yamaki Y (2016)	1
NIN	4	CCNB1	3	bioid	Gupta GD (2015)	1
CDK5	0	CDC25C	0	enzymatic study	Chang KH (2012)	1
CCNB1	3	XIAP	0	pull down	Hou Y (2017)	1
LRRFIP1	6	PRKDC	12	biochemical	Kristensen AR (2012)	1
CCNB1	3	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	van Zon W (2010), Izawa D (2011), Voets E (2015), Voets E (2015)	4
UBE3D	0	CCNB1	3	pull down, enzymatic study	Kobirumaki F (2005), Kobirumaki F (2005)	2
RB1	2	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
XPO1	8	CDC27	2	affinity chromatography technology	Kirli K (2015)	1
CDC5L	2	ZC3HC1	1	affinity chromatography technology	Lleres D (2010)	1
XPO1	8	CCNB2	3	affinity chromatography technology	Kirli K (2015)	1
CDC25C	0	PCNA	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Kawabe T (2002), Kawabe T (2002), Kawabe T (2002), Ando T (2001)	4
CDC20	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Amador V (2007), Fogeron ML (2013)	2
USP14	1	CCNB1	3	enzymatic study	Lee BH (2016)	1
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
CDK7	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	TP73	2	enzymatic study	Gaiddon C (2003)	1
PPP1CB	9	GAS2L1	2	affinity chromatography technology	Hein MY (2015)	1
DNMT1	5	RB1	2	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Robertson KD (2000), Robertson KD (2000), Robertson KD (2000), Pradhan S (2002), Pradhan S (2002)	5
CCNB1	3	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	3
TP53BP1	3	TP73	2	affinity chromatography technology	Woods NT (2012)	1
CDK2	0	TRIM28	1	affinity chromatography technology	Neganova I (2011)	1
UHRF2	1	CDK1	0	far western blotting	Mori T (2011)	1
OFD1	3	DIAPH3	7	bioid	Gupta GD (2015)	1
CCNB2	3	TGFBR2	0	pull down, pull down	Liu JH (1999), Liu JH (1999)	2
HDAC1	4	PPP1CA	3	affinity chromatography technology, affinity chromatography technology	Guo C (2007), Chen CS (2005)	2
CDC27	2	CDKN1A	1	affinity chromatography technology	Amador V (2007)	1
PPP1CA	3	XPO1	8	biochemical	Kristensen AR (2012)	1
PRKN	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lee SB (2015), Lee SB (2015), Lee SB (2015)	3
CDK1	0	CCNB1IP1	0	enzymatic study	Toby GG (2003)	1
SKP2	2	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
PTMA	2	CDK1	0	biochemical	Freire J (2001)	1
CDKN1A	1	GAPDH	0	affinity chromatography technology, pull down	Carujo S (2006), Carujo S (2006)	2
UHRF2	1	RB1	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Lai M (2016)	5
CDK2	0	CDC5L	2	enzymatic study	Boudrez A (2000)	1
XPO1	8	GRWD1	3	affinity chromatography technology	Kirli K (2015)	1
OTUB1	0	FOXM1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Karunarathna U (2016), Karunarathna U (2016), Wang Y (2016), Wang Y (2016), Wang Y (2016), Wang Y (2016), Wang Y (2016)	7
CDK2	0	PRDX1	1	affinity chromatography technology	Neganova I (2011)	1
TRIM28	1	E2F3	0	affinity chromatography technology, affinity chromatography technology	Chen L (2012), Chen L (2012)	2
FOXM1	3	HERC5	2	affinity chromatography technology	Li X (2015)	1
VCP	6	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Fogeron ML (2013)	2
PRKN	1	PSMA6	1	affinity chromatography technology	Sarraf SA (2013)	1
PRKN	1	MFN1	6	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Glauser L (2011), Glauser L (2011), Sun Y (2012), Sarraf SA (2013), Kane LA (2014)	5
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
ANAPC11	0	CCNB1	3	pull down	Frye JJ (2013)	1
IKZF5	0	CDK1	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
VCP	6	CDC27	2	affinity chromatography technology	Yu CC (2013)	1
USP14	1	PSMA6	1	affinity chromatography technology	Sowa ME (2009)	1
OTUB1	0	CCNB1	3	affinity chromatography technology	Scholz CC (2016)	1
PPP1CC	2	PPP1CA	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017)	8
HIST1H1A	0	STAU1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP37	1	PPP1CB	9	bioid	Yeh C (2015)	1
CAND1	2	CCNB1	3	affinity chromatography technology	Bennett EJ (2010)	1
PRKN	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kao SY (2009), Kao SY (2009), Zhu X (2017), Zhu X (2017), Zhu X (2017)	5
CDC20	1	ANAPC11	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study	Nilsson J (2008), Chen TC (2014), Lee SB (2015), Alfieri C (2016)	4
FBF1	2	CEP170	4	bioid	Gupta GD (2015)	1
PSMA6	1	CDK1	0	affinity chromatography technology	Sharma SS (2011)	1
BTRC	1	CDC25A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Ray D (2005), Jin J (2003), Jin J (2003), Honaker Y (2010), Honaker Y (2010), Gao D (2009), Donzelli M (2004), Donzelli M (2004), Jin J (2005), Busino L (2003), Busino L (2003), Busino L (2003), Busino L (2003), Kim TY (2014), Jin J (2003), Coyaud E (2015), Loveless TB (2015), Coyaud E (2015), He N (2005), He N (2005), St-Denis N (2016), Huttlin EL (2017)	23
USP37	1	ANAPC4	0	bioid	Yeh C (2015)	1
PARVA	0	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
UBE2D2	0	UHRF2	1	two hybrid	van Wijk SJ (2009)	1
CDC5L	2	CDC20	1	affinity chromatography technology	Lleres D (2010)	1
VCP	6	DIAPH3	7	affinity chromatography technology	Yu CC (2013)	1
CDK2	0	RPS18	1	affinity chromatography technology	Neganova I (2011)	1
CDKN1B	1	HIST1H1A	0	enzymatic study	Ciarallo S (2002)	1
SNW1	0	RPA1	0	affinity chromatography technology	Lleres D (2010)	1
SPICE1	2	NDC80	4	bioid	Gupta GD (2015)	1
STAU1	1	CDK1	0	affinity chromatography technology	Milev MP (2012)	1
ZADH2	0	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
CCNB1	3	RB1	2	enzymatic study, enzymatic study	Jiang W (1998), Knudsen ES (1997)	2
XPO1	8	RPS3	0	affinity chromatography technology	Kirli K (2015)	1
CEP128	1	CDC20	1	bioid	Gupta GD (2015)	1
BCLAF1	5	FXR1	0	affinity chromatography technology	Hein MY (2015)	1
CCNB1	3	CCNF	2	affinity chromatography technology	Kong M (2000)	1
CDK5	0	TRAP1	0	affinity chromatography technology	Varjosalo M (2013)	1
CDK2	0	USP37	1	enzymatic study, bioid	Huang X (2011), Yeh C (2015)	2
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
CCNB1	3	FZR1	1	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Ke PY (2004), Huang NJ (2012), Pfleger CM (2001), Miller JJ (2006), Song MS (2011), Frye JJ (2013), Lau AW (2013), Brown NG (2014), Summers MK (2009), ODonovan KJ (2010), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Lu L (2013), Yamaguchi M (2015), Brown NG (2015), Chen TC (2014), Williamson A (2011), Qiao R (2016), Brown NG (2016), Huttlin EL (2017)	22
VCP	6	ESPL1	2	affinity chromatography technology	Yu CC (2013)	1
CEP128	1	CNTRL	5	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
CCAR1	7	CAND1	2	biochemical	Wan C (2015)	1
CAND1	2	CDC5L	2	affinity chromatography technology	Bennett EJ (2010)	1
CDK5	0	RB1	2	enzymatic study	Moorthamer M (1999)	1
ANAPC4	0	ANAPC11	0	affinity chromatography technology, biochemical, biochemical, pull down, biochemical, affinity chromatography technology	Mansfeld J (2011), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015)	6
PRKN	1	PRDX1	1	affinity chromatography technology	Zanon A (2013)	1
EP300	36	RELA	1	enzymatic study, two hybrid, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Hiroi M (2003), Nicot C (2001), Kim RH (2001), Hassa PO (2008), Hassa PO (2008), Hu J (2004), Naeaer AM (1999), Lee IT (2010), Nehra R (2010), Hsu HC (2007), Hsu HC (2007), Saha RN (2007), Saha RN (2007), Hassa PO (2003), Hassa PO (2003), Mendonca DB (2011), Chen W (2008), Chen LF (2002), OHara A (2014), Lu Y (2013), Lu Y (2013), Ren YB (2015), Chen LF (2005), Chen LF (2005), Chen LF (2005), Deng WG (2003)	31
PCNA	0	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology	Milutinovic S (2002), Milutinovic S (2002), Naryzhny SN (2004)	3
CDC14A	4	NIN	4	bioid	St-Denis N (2016)	1
CCNB1	3	FOXO1	2	imaging technique	Chen TC (2014)	1
CDK5	0	CDC25A	2	enzymatic study	Chang KH (2012)	1
CHST15	1	CCNB1	3	affinity chromatography technology	Hein MY (2015)	1
SIRT1	3	GAPDH	0	affinity chromatography technology, pull down	Kornberg MD (2010), Kornberg MD (2010)	2
PRKN	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
E2F3	0	PCNA	0	affinity chromatography technology	von Eyss B (2011)	1
PCNA	0	GAPDH	0	affinity chromatography technology, pull down	Naryzhny SN (2010), Naryzhny SN (2010)	2
FBF1	2	OFD1	3	bioid	Gupta GD (2015)	1
UHRF2	1	BCLAF1	5	affinity chromatography technology	Lai M (2016)	1
UBE2K	0	UBE2D2	0	biochemical	Wan C (2015)	1
CAND1	2	RPS3	0	affinity chromatography technology	Bennett EJ (2010)	1
PCM1	5	STAU1	1	bioid	Gupta GD (2015)	1
CDK2	0	POLA1	0	enzymatic study, affinity chromatography technology, enzymatic study	Matsuo K (2000), Dehde S (2001), Dehde S (2001)	3
CNTRL	5	OFD1	3	bioid	Gupta GD (2015)	1
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
PTMA	2	CDK2	0	biochemical	Freire J (2001)	1
VCP	6	BCLAF1	5	affinity chromatography technology	Yu CC (2013)	1
CDK1	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Deep G (2006), Olsen BB (2008), Porter LA (2002), Kabuta T (2013), Ling YH (1998), Thompson LJ (1996), Vincent I (2001)	7
CKS1B	0	PKMYT1	1	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	TP73	2	affinity chromatography technology	Ibrahim N (2010)	1
CDC20	1	CCNB1	3	enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Garnett MJ (2009), ODonovan KJ (2010), Ke PY (2004), Braunstein I (2007), van Zon W (2010), van Zon W (2010), Pfleger CM (2001), Wolthuis R (2008), Kwan PS (2013), Tian W (2012), Han JS (2013), Lim HJ (2013), Han JS (2014), Brown NG (2014), Townsend K (2009), Sedgwick GG (2013), Lara-Gonzalez P (2011), Wu T (2010), Shoji S (2014), Vodermaier HC (2003), Kim HS (2011), Wu T (2010), Uzunova K (2012), Shoji S (2014), Sedgwick GG (2013), Lara-Gonzalez P (2011), Diaz-Martinez LA (2015), Brown NG (2015), Lischetti T (2014), Tipton AR (2013), Lee SB (2015), Lee SB (2015), Jia L (2016)	33
CCNF	2	CDC20	1	affinity chromatography technology	Choudhury R (2016)	1
CEP128	1	FBF1	2	bioid	Gupta GD (2015)	1
OFD1	3	CDK2	0	bioid	Gupta GD (2015)	1
CDC25A	2	CDC20	1	affinity chromatography technology	Li X (2016)	1
CDC25B	4	CDC20	1	affinity chromatography technology	Li X (2016)	1
FZR1	1	STAU1	1	affinity chromatography technology, affinity chromatography technology	Boulay K (2014), Boulay K (2014)	2
CNTRL	5	SQSTM1	0	bioid	Gupta GD (2015)	1
RPS18	1	RPS3	0	biochemical, biochemical	Kristensen AR (2012), Wan C (2015)	2
CDK1	0	CDK7	0	enzymatic study	Garrett S (2001)	1
BRCA1	7	RPS18	1	affinity chromatography technology	Ertych N (2016)	1
CDK2	0	BCLAF1	5	affinity chromatography technology	Hein MY (2015)	1
GADD45B	1	CCNB1	3	pull down	Vairapandi M (2002)	1
CDC5L	2	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
GADD45A	1	CDKN1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhao H (2000), Zhao H (2000), Yang Q (2000), Yang Q (2000)	4
TP73	2	CDT1	2	affinity chromatography technology	Lunardi A (2010)	1
CCNB1	3	RNASEH2C	0	biochemical	Wan C (2015)	1
PSMA6	1	CCNB1	3	affinity chromatography technology	Sharma SS (2011)	1
PCM1	5	CCNB2	3	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CCNB1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Yang Q (2000), Pines J (1989), Kong M (2000), Amador V (2007), Paulsen MT (2006), Niida H (2005), Pereg Y (2010), Tamura D (2010), Kiviharju-af Haellstroem TM (2007), Pan ZQ (1993), Pan ZQ (1993), Pan ZQ (1993), van Zon W (2010), Desai D (1995), Vazquez-Novelle MD (2010), Smith EM (2008), Poon RY (1996), OConnor PM (1993), Fosbrink M (2009), Linares JF (2011), Varjosalo M (2013), Felzien LK (1998), Toby GG (2003), So J (2015), Huttlin EL (2015), Wan C (2015), Jenkins RH (2014), Hein MY (2015), Hein MY (2015), Voets E (2015), Lin Z (2015), Lin Z (2015), Huttlin EL (2017)	34
PRKN	1	UBE2K	0	pull down	Kazlauskaite A (2014)	1
E2F3	0	CCNB1	3	affinity chromatography technology	von Eyss B (2011)	1
BRCA1	7	PRDX1	1	affinity chromatography technology	Ertych N (2016)	1
PRKN	1	GAPDH	0	biochemical, affinity chromatography technology	Schlehe JS (2008), Zanon A (2013)	2
PRKDC	12	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Gong Z (2011), Marechal A (2014)	3
CCNB1	3	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
CDK1	0	POLA1	0	enzymatic study	Dehde S (2001)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
SIRT1	3	DIAPH3	7	affinity chromatography technology	Law IK (2009)	1
FZR1	1	CDC16	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Hein MY (2015), Huttlin EL (2017)	3
BTRC	1	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013), Fukushima H (2013)	3
XPO1	8	BCLAF1	5	affinity chromatography technology	Kirli K (2015)	1
CDK2	0	CDC25B	4	two hybrid, enzymatic study	Conklin DS (1995), Cheng A (2005)	2
CDC14A	4	FZR1	1	enzymatic study	Bembenek J (2001)	1
DNMT1	5	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson KD (2000), Achour M (2008), Achour M (2008), Kimura H (2003), Zhang Q (2005), Myant K (2008), Schnekenburger M (2007), Kang KA (2012), Cui S (2011), Cui S (2011), Hervouet E (2010), Cai Y (2014), Cai Y (2014), Yuan K (2016), Yuan K (2016)	15
CCDC6	3	TRIM28	1	biochemical	Kristensen AR (2012)	1
CCNB1	3	RPA1	0	enzymatic study	Pan ZQ (1993)	1
NIN	4	DIAPH3	7	bioid	Gupta GD (2015)	1
CCNB2	3	RNASEH2C	0	biochemical	Wan C (2015)	1
CDC5L	2	HNRNPLL	1	affinity chromatography technology	Lleres D (2010)	1
OTUB1	0	PRDX1	1	affinity chromatography technology	Scholz CC (2016)	1
SQSTM1	0	RPTOR	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Duran A (2011), Duran A (2011), Linares JF (2015)	3
BRCA1	7	RPTOR	4	affinity chromatography technology	Ertych N (2016)	1
CDK2	0	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Ruffner H (1999), Ruffner H (1999), Ruffner H (1999), Wang H (1997), Chen Y (1996)	5
STAU1	1	XPO1	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Milev MP (2012), Milev MP (2012), Milev MP (2012)	3
GADD45B	1	CDK1	0	pull down	Vairapandi M (2002)	1
OTUB1	0	PCNA	0	affinity chromatography technology	Edelmann MJ (2009)	1
XPO1	8	PDCD6	2	affinity chromatography technology	Kirli K (2015)	1
GADD45A	1	GADD45G	0	affinity chromatography technology	Kovalsky O (2001)	1
CCNB1	3	RHOBTB3	1	affinity chromatography technology	Lu A (2013)	1
TGFBR2	0	CDC6	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCNB1	3	TP73	2	pull down	Gaiddon C (2003)	1
PPP1CA	3	DCTN1	6	two hybrid	Esteves SL (2012)	1
USP37	1	SIRT1	3	bioid	Yeh C (2015)	1
SP1	0	SKP2	2	affinity chromatography technology	Tapias A (2008)	1
RB1	2	CDC16	2	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC5L	2	NDC80	4	affinity chromatography technology	Lleres D (2010)	1
CCNB1	3	CDC14A	4	affinity chromatography technology	Paulsen MT (2006)	1
XPO1	8	SPICE1	2	affinity chromatography technology	Kirli K (2015)	1
CDK2	0	PRKDC	12	affinity chromatography technology	Neganova I (2011)	1
CDK2	0	CDC25C	0	enzymatic study, enzymatic study	Cheng A (2005), Sebastian B (1993)	2
CCDC6	3	HDAC1	4	affinity chromatography technology, pull down, imaging technique, biochemical	Leone V (2010), Leone V (2010), Leone V (2010), Kristensen AR (2012)	4
BRCA1	7	DCTN1	6	affinity chromatography technology	Ertych N (2016)	1
PPP1CC	2	NDC80	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BTRC	1	CAND1	2	affinity chromatography technology	Coyaud E (2015)	1
CDK1	0	USP22	1	affinity chromatography technology	Lin Z (2015)	1
KEAP1	0	RELA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Yu M (2011), Yu M (2011), Yu M (2011), Yu M (2011), Wang J (2011), Wang J (2011)	6
UHRF2	1	CDC16	2	affinity chromatography technology	Lai M (2016)	1
RPA1	0	CDK7	0	affinity chromatography technology	Marechal A (2014)	1
GADD45A	1	CDK1	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Zhan Q (1999), Jin S (2000), Jin S (2000), Yang Q (2000), Yang Q (2000), Vairapandi M (2002), Zhan Q (1999), Zhan Q (1999), Zhang Y (2009)	9
PRKDC	12	PRDX1	1	biochemical	Kristensen AR (2012)	1
POLA1	0	RB1	2	affinity chromatography technology, biochemical	Takemura M (1997), Takemura M (1997)	2
CKS2	0	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CDK3	0	RB1	2	enzymatic study, enzymatic study	Connell-Crowley L (1997), Ren S (2004)	2
GADD45A	1	DNMT1	5	affinity chromatography technology	Lee B (2011)	1
TP53BP1	3	TRIM28	1	affinity chromatography technology	Lin YH (2015)	1
MGMT	1	PCNA	0	affinity chromatography technology	Niture SK (2005)	1
CDK1	0	RPA1	0	enzymatic study, enzymatic study	Pan ZQ (1993), Pan ZQ (1993)	2
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
CEP128	1	CDK5	0	bioid	Gupta GD (2015)	1
UBE2D2	0	CDKN1B	1	enzymatic study	Ryu KS (2008)	1
CDK5	0	HIST1H1B	4	enzymatic study	Vincent I (2001)	1
SQSTM1	0	UBE2D2	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Peng H (2017), Peng H (2017), Peng H (2017), Peng H (2017), Peng H (2017)	5
CCNB1	3	BCLAF1	5	affinity chromatography technology	Lin Z (2015)	1
SET	8	XPO1	8	affinity chromatography technology	Saito S (2004)	1
CDK2	0	AKR7A2	1	affinity chromatography technology	Hein MY (2015)	1
ARID4A	3	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lai A (1999), Lai A (1999), Lai A (2001), Lai A (2001), Suryadinata R (2011), Suryadinata R (2011)	6
TP53BP1	3	CDC16	2	affinity chromatography technology	Woods NT (2012)	1
SP1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Padova M (2003), Singh J (2002), Zhang Y (2002), Sun JM (2002), Gao J (2009), Shon JK (2009), Mottet D (2009), Goto T (2006), Hung JJ (2006), Lagger G (2003), Choi HS (2002), Choi HS (2002), Kang JE (2005), Kang JE (2005), Kang JE (2005), Gan Y (2005), Gan Y (2005), Duan H (2005), Varshochi R (2005), Varshochi R (2005), Plaisance V (2005), Walker GE (2001), Walker GE (2001), Ammanamanchi S (2004), Doetzlhofer A (1999), Sekhavat A (2007), Liu T (2007), Enya K (2008), Liu S (2010), Leclerc GJ (2010), Leclerc GJ (2010), Wong CY (2011), Schnur N (2007)	33
PTMA	2	KEAP1	0	pull down, unspecified method, x-ray crystallography, two hybrid, pull down	Khan H (2013), Khan H (2013), Khan H (2013), Rolland T (2014), Khan H (2015)	5
CDK1	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radu M (2008), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDC25B	4	CDC5L	2	affinity chromatography technology	Hein MY (2015)	1
PPP1CB	9	PPP1CC	2	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
CDC27	2	PCNA	0	affinity chromatography technology	Williamson A (2011)	1
VCP	6	CDKN1A	1	affinity chromatography technology	Yu CC (2013)	1
VCP	6	GRWD1	3	affinity chromatography technology	Fogeron ML (2013)	1
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CKS1B	0	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Wang W (2003), Sitry D (2002), Zhou W (2009), Ooi LC (2013), Huttlin EL (2017)	5
CCNB1IP1	0	CCNB1	3	two hybrid	Toby GG (2003)	1
FBF1	2	CCNB1	3	bioid	Gupta GD (2015)	1
CCNB1	3	NCBP1	7	affinity chromatography technology	Hein MY (2015)	1
PRKN	1	MARCH5	0	affinity chromatography technology	Sarraf SA (2013)	1
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
CEP128	1	NIN	4	bioid, bioid	Gupta GD (2015), Gupta GD (2015)	2
LLGL2	4	SQSTM1	0	affinity chromatography technology	Hauri S (2013)	1
GADD45A	1	GAPDH	0	two hybrid	Vinayagam A (2011)	1
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
CDK1	0	TSPYL2	4	enzymatic study	Chai Z (2001)	1
CDC14A	4	CEP162	3	bioid	St-Denis N (2016)	1
FOXO1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang H (2005), Huang H (2005), Huang H (2005), Calvisi DF (2009), Park J (2018), Park J (2018)	6
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
USP37	1	HDAC1	4	bioid	Yeh C (2015)	1
PCM1	5	CEP162	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, bioid	Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015), Gupta GD (2015)	5
CCNB1	3	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jeganathan KB (2006), Farhana L (2002), van Zon W (2010), Miller JJ (2006), Voets E (2015)	5
MGMT	1	CDK1	0	affinity chromatography technology	Niture SK (2005)	1
PRKDC	12	HIST1H1A	0	enzymatic study	Li A (2010)	1
CCNB1	3	TRIM28	1	affinity chromatography technology, affinity chromatography technology	Lin Z (2015), Lin Z (2015)	2
CDK2	0	PRC1	4	enzymatic study	Jiang W (1998)	1
FOXM1	3	SP1	0	imaging technique, pull down, affinity chromatography technology	Xu K (2013), Xu K (2013), Xu K (2013)	3
GADD45G	0	PCNA	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Azam N (2001), Azam N (2001), Azam N (2001), Nakayama K (1999)	4
UHRF2	1	CCNB1	3	far western blotting, affinity chromatography technology, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011)	3
RELA	1	PRKDC	12	affinity chromatography technology	Veena MS (2014)	1
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CCNB1	3	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Hein MY (2015), Huttlin EL (2017)	3
CCNB1	3	RELA	1	affinity chromatography technology	Felzien LK (1998)	1
ANAPC11	0	ANAPC10	0	pull down	Tang Z (2001)	1
CDC6	0	POLA1	0	biochemical	Wan C (2015)	1
BRCA1	7	CDC5L	2	affinity chromatography technology	Ertych N (2016)	1
PPP1CC	2	STAU1	1	two hybrid	Esteves SL (2012)	1
CDC20	1	BTRC	1	affinity chromatography technology	Guardavaccaro D (2008)	1
SNW1	0	NDC80	4	affinity chromatography technology	Lleres D (2010)	1
CDC25A	2	VCP	6	affinity chromatography technology	Riemer A (2014)	1
PRPSAP2	1	CCNB1	3	affinity chromatography technology	Huttlin EL (2017)	1
CEP170	4	CCNB1	3	bioid	Gupta GD (2015)	1
PRKN	1	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down	Joch M (2007), Imai Y (2002), Chaugule VK (2011), Durcan TM (2011), Caulfield TR (2014), Kazlauskaite A (2014)	6
TP53BP1	3	CDC27	2	affinity chromatography technology	Woods NT (2012)	1
BTRC	1	PRDX1	1	two hybrid	Wang J (2011)	1
CNTRL	5	CEP162	3	bioid	Gupta GD (2015)	1
TP73	2	RB1	2	affinity chromatography technology	Ozaki T (2003)	1
CCAR1	7	DCTN1	6	biochemical	Wan C (2015)	1
CDC5L	2	TRAP1	0	affinity chromatography technology	Lleres D (2010)	1
PCNA	0	CDC6	0	two hybrid	Saha P (1998)	1
RPA1	0	PPP1CC	2	affinity chromatography technology	Marechal A (2014)	1
UHRF2	1	RPA1	0	affinity chromatography technology	Lai M (2016)	1
CCDC6	3	RPTOR	4	affinity chromatography technology	Huttlin EL (2017)	1
CAND1	2	BCLAF1	5	affinity chromatography technology	Bennett EJ (2010)	1