PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
APBB1	3	ABI1	1	pull down	Ingham RJ (2005)	1
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
PFN1	0	WASF1	10	affinity chromatography technology, far western blotting	Miki H (1998), Miki H (1998)	2
HSP90AB1	2	ACTG1	5	affinity chromatography technology	Falsone SF (2005)	1
HSP90AB1	2	SRC	2	affinity chromatography technology	Karras GI (2017)	1
SRC	2	IQGAP1	1	affinity chromatography technology	Meyer RD (2008)	1
TRIP10	1	WASL	2	pull down, biochemical	Tsujita K (2006), Wan C (2015)	2
SNX9	1	WASL	2	pull down	Shin N (2008)	1
NCK2	2	BAIAP2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WASL	2	WASF1	10	biochemical	Wan C (2015)	1
388474	0	WASL	2	two hybrid	Wang J (2011)	1
ELAVL1	0	SKA1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
IQGAP1	1	ARPC3	0	affinity chromatography technology	Hein MY (2015)	1
PACSIN2	0	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
NCK2	2	WASF2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRPF40A	5	WASL	2	pull down	Ingham RJ (2005)	1
ARPC1B	1	ARPC3	0	biochemical, biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015)	4
NTRK1	1	HSP90AB1	2	affinity chromatography technology	Emdal KB (2015)	1
WIPF1	0	ABI2	4	two hybrid	Rolland T (2014)	1
FCHSD2	3	HSP90AB1	2	two hybrid	Thalappilly S (2008)	1
IQGAP1	1	WASL	2	affinity chromatography technology	Carmon KS (2014)	1
NTRK1	1	PFN1	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	WASF2	0	affinity chromatography technology	Emdal KB (2015)	1
CDC42	3	WIPF1	0	pull down	Martinez-Quiles N (2001)	1
WASL	2	HSP90AB1	2	pull down, pull down	Park SJ (2005), Park SJ (2005)	2
PFN1	0	WASL	2	pull down, pull down, affinity chromatography technology	Mimuro H (2000), Suetsugu S (1998), Suetsugu S (1998)	3
ITSN1	5	PACSIN3	2	two hybrid	Wong KA (2012)	1
NCK2	2	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Chen M (1998), Braverman LE (1999), Tu Y (1998), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
PACSIN3	2	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
NTRK1	1	ABI2	4	affinity chromatography technology	Emdal KB (2015)	1
APBB1	3	EGFR	5	unspecified method	Jones RB (2006)	1
ELAVL1	0	FCHSD2	3	affinity chromatography technology	Abdelmohsen K (2009)	1
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
ABI1	1	WASL	2	biochemical	Wan C (2015)	1
BAIAP2	6	WASL	2	two hybrid, affinity chromatography technology	Wang J (2011), Hein MY (2015)	2
PACSIN2	0	PACSIN1	0	two hybrid, two hybrid, pull down, pull down, two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Modregger J (2000), Modregger J (2000), Modregger J (2000), Modregger J (2000), Bandyopadhyay S (2010), Rolland T (2014), Huttlin EL (2017)	8
ELAVL1	0	WASL	2	affinity chromatography technology	Abdelmohsen K (2009)	1
SDCBP	0	PRPF40A	5	two hybrid	Rolland T (2014)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
ELAVL1	0	RHOQ	0	affinity chromatography technology	Abdelmohsen K (2009)	1
NCK2	2	WASF3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LSM1	0	HSP90AA1	7	two hybrid	Lehner B (2004)	1
IQGAP1	1	GSN	3	affinity chromatography technology	Hein MY (2015)	1
LCK	0	WASL	2	enzymatic study	Torres E (2006)	1
EGFR	5	BAIAP2	6	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013)	4
FNBP1	0	WASL	2	biochemical, pull down	Havugimana PC (2012), Tsujita K (2006)	2
IQGAP1	1	HSP90AB1	2	affinity chromatography technology	Hein MY (2015)	1
ITSN2	7	WIPF2	1	two hybrid	Wong KA (2012)	1
EGFR	5	ITSN2	7	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
BAIAP2	6	CDC42	3	far western blotting, affinity chromatography technology, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology	Soltau M (2002), Krugmann S (2001), Krugmann S (2001), Miki H (2000), Bandyopadhyay S (2010), Govind S (2001), Govind S (2001)	7
NTRK1	1	SNX9	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	PRPF40A	5	affinity chromatography technology	Emdal KB (2015)	1
ITSN1	5	FCHSD2	3	two hybrid	Wong KA (2012)	1
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
SH3KBP1	1	WASL	2	affinity chromatography technology	Havrylov S (2009)	1
ITSN1	5	ITSN2	7	protein complementation assay	Wong KA (2012)	1
WASL	2	GRB2	2	pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Carlier MF (2000), Bandyopadhyay S (2010), Bisson N (2011), Rolland T (2014), Huttlin EL (2017)	5
WASL	2	GSN	3	x-ray crystallography	Aguda AH (2006)	1
SH3KBP1	1	WIPF2	1	affinity chromatography technology	Havrylov S (2009)	1
WASF2	0	ACTR3	1	pull down	Suetsugu S (1999)	1
PACSIN2	0	PACSIN3	2	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Modregger J (2000), Modregger J (2000), Modregger J (2000), Huttlin EL (2015), Huttlin EL (2017)	5
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
RHOQ	0	TRIP10	1	two hybrid, affinity chromatography technology, pull down	Chang L (2002), Chang L (2002), Chang L (2002)	3
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
VIPR1	2	WASL	2	pull down	Mimuro H (2000)	1
EGFR	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soubeyran P (2002), Szymkiewicz I (2002), Schmidt MH (2004), Schmidt MH (2003), Ronning SB (2011), Ronning SB (2011), Yang S (2006), Schmidt MH (2003)	8
ITSN2	7	WASF2	0	two hybrid	Wong KA (2012)	1
WASL	2	WIPF2	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
WASL	2	ASPA	1	affinity chromatography technology	Huttlin EL (2017)	1
ABI2	4	WASL	2	biochemical	Wan C (2015)	1
EGFR	5	WASL	2	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
ACTG1	5	ACTBL2	0	biochemical	Kristensen AR (2012)	1
SORBS3	5	WASL	2	affinity chromatography technology	Ito H (2008)	1
SH3KBP1	1	WIPF1	0	affinity chromatography technology	Havrylov S (2009)	1
ELAVL1	0	SH3KBP1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	FNBP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
ABI1	1	WASF2	0	pull down, biochemical, affinity chromatography technology	Hirao N (2006), Wan C (2015), Hein MY (2015)	3
SDCBP	0	ABI2	4	two hybrid	Rolland T (2014)	1
GRB2	2	ACTG1	5	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Li J (2013)	2
APP	1	SRC	2	affinity chromatography technology	Austin SA (2009)	1
WWOX	3	PRPF40A	5	affinity chromatography technology	Abu-Odeh M (2014)	1
ABI1	1	WASF1	10	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Boldt K (2016)	3
ARPC1B	1	APP	1	pull down	Olah J (2011)	1
ITSN2	7	FCHSD2	3	two hybrid	Wong KA (2012)	1
WASL	2	RNF8	2	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
DNMBP	9	WASL	2	affinity chromatography technology	Salazar MA (2003)	1
LCK	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Taipale M (2012)	2
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
ACTR2	2	ARPC3	0	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
ITSN1	5	CDC42	3	affinity chromatography technology, pull down, x-ray crystallography	Hussain NK (2001), Hussain NK (2001), Snyder JT (2002)	3
CDC42	3	FNBP1L	2	affinity chromatography technology	Ho HY (2004)	1
ELAVL1	0	3240	0	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	SDCBP	0	two hybrid	Rolland T (2014)	1
NCK2	2	NCK1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PFN1	0	VIPR1	2	pull down	Mimuro H (2000)	1
FNBP1L	2	PACSIN3	2	biochemical	Wan C (2015)	1
ITSN2	7	SH3KBP1	1	two hybrid	Wong KA (2012)	1
WASL	2	ATG4C	1	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	SNX9	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CTTN	1	WIPF1	0	two hybrid, pull down, affinity chromatography technology	Kinley AW (2003), Kinley AW (2003), Kinley AW (2003)	3
PRPF40A	5	ABI1	1	pull down	Ingham RJ (2005)	1
EGFR	5	WASF3	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
WASF3	3	ACTR3	1	pull down	Suetsugu S (1999)	1
CTTN	1	ACTR2	2	affinity chromatography technology, pull down, affinity chromatography technology	Weed SA (2000), Uruno T (2003), Hein MY (2015)	3
ABI2	4	WASF3	3	affinity chromatography technology	Huttlin EL (2017)	1
ABI1	1	NCK1	0	pull down, affinity chromatography technology	Yamamoto A (2001), Cowan CA (2001)	2
DNMBP	9	WIPF3	3	affinity chromatography technology	Salazar MA (2003)	1
CTTN	1	WASL	2	affinity chromatography technology, far western blotting, affinity chromatography technology	Mizutani K (2002), Mizutani K (2002), Lynch DK (2003)	3
NTRK1	1	ARPC1B	1	affinity chromatography technology	Emdal KB (2015)	1
WASL	2	NCK1	0	far western blotting, pull down, affinity chromatography technology	Rohatgi R (2001), Rohatgi R (2001), Hein MY (2015)	3
ACTR2	2	GSN	3	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	WASL	2	affinity chromatography technology	Emdal KB (2015)	1
BIN1	2	WASL	2	pull down	Falcone S (2014)	1
PSTPIP1	3	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
ELAVL1	0	CDC42	3	affinity chromatography technology	Abdelmohsen K (2009)	1
NTRK1	1	IQGAP1	1	affinity chromatography technology	Emdal KB (2015)	1
WASL	2	WIPF1	0	pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology	Zettl M (2002), Martinez-Quiles N (2001), Martinez-Quiles N (2001), Martinez-Quiles N (2001), Rolland T (2014), Huttlin EL (2017)	6
NCK2	2	WIPF3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WASL	2	RHOQ	0	pull down, two hybrid	Abe T (2003), Abe T (2003)	2
HSP90AA1	7	PTK6	1	affinity chromatography technology	Taipale M (2012)	1
WASL	2	WASF3	3	biochemical	Wan C (2015)	1
WIPF1	0	NCK1	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Anton IM (1998), Anton IM (1998), Hein MY (2015)	3
PTK6	1	APP	1	pull down	Olah J (2011)	1
NTRK1	1	SRC	2	affinity chromatography technology	Emdal KB (2015)	1
ITSN1	5	WASL	2	pull down	Hussain NK (2001)	1
NTRK1	1	ACTR2	2	affinity chromatography technology	Emdal KB (2015)	1
WASL	2	CDC42	3	pull down, pull down, two hybrid, pull down	Carlier MF (2000), Miki H (1998), Bandyopadhyay S (2010), Martinez-Quiles N (2001)	4
EGFR	5	PTK6	1	affinity chromatography technology, unspecified method	Kamalati T (1996), Jones RB (2006)	2
WASL	2	ARPC1B	1	affinity chromatography technology	Osiak AE (2005)	1
FCHSD2	3	WASL	2	two hybrid	Wang J (2011)	1
PACSIN2	0	WASL	2	pull down	Modregger J (2000)	1
APBB1	3	APP	1	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Borg JP (1996), Borg JP (1996), Borg JP (1996), Zambrano N (1997), Guenette SY (1996), Tanahashi H (1999), Trommsdorff M (1998), Trommsdorff M (1998), Kim SY (2007), Sumioka A (2005), von Rotz RC (2004), Cao X (2004), Cao X (2004), Kajiwara Y (2010), Viswanathan J (2013), Lee MR (2008), Huttlin EL (2017)	17
NTRK1	1	ACTR3	1	affinity chromatography technology	Emdal KB (2015)	1
WASL	2	APP	1	pull down	Olah J (2011)	1
NCK2	2	WIPF1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRPF40A	5	WASF2	0	pull down	Ingham RJ (2005)	1
ACTR3	1	ARPC3	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Gournier H (2001), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
APBB1	3	WIPF2	1	pull down	Ingham RJ (2005)	1
IQGAP1	1	CTTN	1	affinity chromatography technology	Hein MY (2015)	1
SKA1	0	WASL	2	affinity chromatography technology	Hein MY (2015)	1
ABI1	1	ABI2	4	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
WWOX	3	WASL	2	affinity chromatography technology	Abu-Odeh M (2014)	1
CTTN	1	ACTG1	5	pull down	Uruno T (2001)	1
PACSIN3	2	WASL	2	pull down	Modregger J (2000)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
IQGAP1	1	PACSIN3	2	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	WIPF3	3	affinity chromatography technology, affinity chromatography technology	Bisson N (2011), Huttlin EL (2017)	2
NTRK1	1	CTTN	1	affinity chromatography technology	Emdal KB (2015)	1
TRIP10	1	RHOJ	0	two hybrid	Rolland T (2014)	1
CTTN	1	ARPC3	0	affinity chromatography technology	Weed SA (2000)	1
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
LCK	0	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
ARPC1B	1	ACTR2	2	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
WWOX	3	WIPF2	1	pull down, affinity chromatography technology	Ingham RJ (2005), Abu-Odeh M (2014)	2
WASF1	10	BAIAP2	6	two hybrid, far western blotting, pull down	Miki H (2000), Miki H (2000), Miki H (2000)	3
WASF1	10	ACTR3	1	pull down	Singh S (2003)	1
WWOX	3	BAIAP2	6	affinity chromatography technology	Abu-Odeh M (2014)	1
NTRK1	1	WASF1	10	affinity chromatography technology	Emdal KB (2015)	1
SRC	2	WASL	2	enzymatic study	Park SJ (2005)	1
ABI2	4	WASF1	10	affinity chromatography technology	Huttlin EL (2017)	1
ELAVL1	0	PFN1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
NCK2	2	WASF1	10	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PTK6	1	WASL	2	two hybrid	Rolland T (2014)	1
EGFR	5	CTTN	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
LSM1	0	WASL	2	biochemical	Havugimana PC (2012)	1
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
WASF3	3	ABI1	1	affinity chromatography technology	Huttlin EL (2017)	1
ITSN2	7	WIPF1	0	two hybrid	Wong KA (2012)	1
IQGAP1	1	ACTG1	5	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Taipale M (2012), Emdal KB (2015)	3
PACSIN2	0	WIPF2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSP90AA1	7	ACTG1	5	affinity chromatography technology	Falsone SF (2005)	1
IQGAP1	1	ACTR3	1	affinity chromatography technology	Hein MY (2015)	1
GSN	3	SRC	2	affinity chromatography technology	Chellaiah MA (2001)	1
ABI1	1	CTTN	1	biochemical	Havugimana PC (2012)	1
ITSN1	5	SH3KBP1	1	affinity chromatography technology	Nikolaienko O (2009)	1
BIN1	2	APP	1	pull down	Olah J (2011)	1
PACSIN1	0	WIPF1	0	affinity chromatography technology	Linkermann A (2009)	1
TRIP10	1	CDC42	3	two hybrid, pull down, pull down	Aspenstroem P (1997), Tian L (2000), Aspenstroem P (1997)	3
GRB2	2	IQGAP1	1	affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Brehme M (2009)	2
WASL	2	ACTR2	2	unspecified method	Uruno T (2003)	1
WASL	2	ACTR3	1	unspecified method	Uruno T (2003)	1
ACTR3	1	ARPC1B	1	biochemical, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Gournier H (2001), Molli PR (2010), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	7
WASF2	0	BAIAP2	6	far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miki H (2000), Miki H (2000), Miki H (2000), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
BAIAP2	6	APP	1	pull down	Olah J (2011)	1
ELAVL1	0	CTTN	1	affinity chromatography technology	Abdelmohsen K (2009)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
ELAVL1	0	GRB2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	ZNF395	1	affinity chromatography technology	Abdelmohsen K (2009)	1
NCK2	2	ABI2	4	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	4
APBB1	3	WASL	2	pull down	Ingham RJ (2005)	1
NTRK1	1	IPO5	0	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	CDC42	3	two hybrid	Vinayagam A (2011)	1
HSP90AB1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Cheng MB (2010), Gano JJ (2010), Skarra DV (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Wan C (2015), Hein MY (2015)	8
NCK1	0	WIPF2	1	affinity chromatography technology	Hein MY (2015)	1
WIPF1	0	ACTG1	5	pull down	Martinez-Quiles N (2001)	1
ELAVL1	0	ZNF638	8	affinity chromatography technology	Abdelmohsen K (2009)	1
IQGAP1	1	ACTR2	2	affinity chromatography technology	Hein MY (2015)	1
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
WASL	2	WIPF3	3	affinity chromatography technology	Huttlin EL (2017)	1
DNMBP	9	WASF1	10	affinity chromatography technology	Salazar MA (2003)	1
ACTBL2	0	GSN	3	affinity chromatography technology	Huttlin EL (2017)	1
IPO5	0	WASL	2	two hybrid	Wang J (2011)	1
GRB2	2	WIPF2	1	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	4
PACSIN1	0	WASL	2	pull down	Modregger J (2000)	1
GRB2	2	HSP90AB1	2	affinity chromatography technology	Brehme M (2009)	1
DNMBP	9	WIPF2	1	affinity chromatography technology	Salazar MA (2003)	1
ELAVL1	0	WIPF1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
SDCBP	0	PSTPIP1	3	two hybrid	Rolland T (2014)	1
WASL	2	ZNF638	8	biochemical	Havugimana PC (2012)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
PSTPIP1	3	WASL	2	pull down	Tsujita K (2006)	1
WASL	2	HSP90AA1	7	pull down	Park SJ (2005)	1
ITSN1	5	FNBP1	0	two hybrid	Wong KA (2012)	1
EGFR	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
3240	0	WASL	2	two hybrid	Wang J (2011)	1
WASF2	0	WASL	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
WWOX	3	ELAVL1	0	affinity chromatography technology	Abu-Odeh M (2014)	1
BAIAP2	6	ABI1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	4
ITSN2	7	WASL	2	two hybrid	Wong KA (2012)	1
ELAVL1	0	BIN1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
BCHE	2	WASL	2	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	IPO5	0	affinity chromatography technology	Foerster S (2013)	1
PACSIN1	0	PACSIN3	2	two hybrid, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology	Modregger J (2000), Modregger J (2000), Modregger J (2000), Modregger J (2000), Rolland T (2014), Huttlin EL (2017)	6
WASL	2	RHOJ	0	two hybrid	Rolland T (2014)	1
APBB1	3	WIPF1	0	pull down	Ingham RJ (2005)	1
WASL	2	ACTBL2	0	affinity chromatography technology	Huttlin EL (2017)	1
EGFR	5	ACTR2	2	affinity chromatography technology	Tong J (2014)	1
GRB2	2	NTRK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Song C (2002), MacDonald JI (2000), Emdal KB (2015), Emdal KB (2015)	4
PRPF40A	5	WIPF1	0	pull down	Ingham RJ (2005)	1
ELAVL1	0	ACTR2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
GRB2	2	WIPF1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Huttlin EL (2017)	4
CTTN	1	ACTR3	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique, pull down	Weed SA (2000), Weed SA (2000), Weed SA (2000), Di Ciano C (2002), Uruno T (2001), Uruno T (2001), Uruno T (2003)	7
WASL	2	ARPC3	0	two hybrid	Rolland T (2014)	1
ABI2	4	WASF2	0	pull down, affinity chromatography technology	Hirao N (2006), Huttlin EL (2017)	2
GRB2	2	CTTN	1	affinity chromatography technology	Brehme M (2009)	1
WASL	2	ZNF395	1	two hybrid	Wang J (2011)	1
SDCBP	0	WASL	2	two hybrid	Rolland T (2014)	1
WASF1	10	TRIP10	1	two hybrid, biochemical	Rolland T (2014), Wan C (2015)	2
GSN	3	APP	1	pull down, affinity chromatography technology	Chauhan VP (1999), Chauhan VP (1999)	2
PFN1	0	RHOQ	0	pull down	Murphy GA (1999)	1
NTRK1	1	ELAVL1	0	affinity chromatography technology	Emdal KB (2015)	1
ACTG1	5	WASL	2	pull down, x-ray crystallography	Gaucher JF (2012), Gaucher JF (2012)	2
NCK2	2	WASL	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
CDC42	3	IQGAP1	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuroda S (1996), Kuroda S (1996), Fukata M (2002), Hart MJ (1996), Hart MJ (1996), Joyal JL (1997), Zhang B (1998), Bourguignon LY (2005), Hein MY (2015), Hein MY (2015)	10
WASF1	10	FNBP1L	2	biochemical	Wan C (2015)	1
ACTR3	1	ACTR2	2	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Gournier H (2001), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
GRB2	2	3240	0	two hybrid	Wang J (2008)	1
EGFR	5	IQGAP1	1	affinity chromatography technology	Casar B (2009)	1
WIPF2	1	NCK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Aspenstroem P (2002), Huttlin EL (2015), Huttlin EL (2017)	3
APBB1	3	WASF2	0	pull down	Ingham RJ (2005)	1
NCK1	0	PFN1	0	pull down	Anton IM (1998)	1
FNBP1L	2	WASL	2	pull down, biochemical	Tsujita K (2006), Wan C (2015)	2
ABI1	1	NCK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cowan CA (2001), Huttlin EL (2015), Huttlin EL (2017)	3