PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
LCK 0 TRAT1 0 pull down Brdicka T (2000) 1
SLA 2 ZAP70 5 affinity chromatography technology Tang J (1999) 1
CD3E 0 LCK 0 affinity chromatography technology, affinity chromatography technology Munoz P (2003), Munoz P (2003) 2
PTPN22 3 CD247 1 affinity chromatography technology Wu J (2006) 1
JAK3 3 STAT5A 4 two hybrid, affinity chromatography technology Fujitani Y (1997), Cheng H (2008) 2
PTPRC 1 LCK 0 affinity chromatography technology, pull down, affinity chromatography technology Koretzky GA (1993), Ng DH (1996), Jury EC (2004) 3
LCK 0 PIK3R1 6 pull down Kapeller R (1994) 1
CSK 3 CD3E 0 pull down Catipovic B (1996) 1
CD3E 0 PIK3R1 6 affinity chromatography technology, affinity chromatography technology de Aos I (1997), Alcazar I (2009) 2
NCR1 1 CD247 1 affinity chromatography technology Vitale M (1998) 1
TUBA1B 0 CD247 1 affinity chromatography technology Serrador JM (2004) 1
LAT 0 PIK3R1 6 affinity chromatography technology, pull down Paz PE (2001), Paz PE (2001) 2
PTPN22 3 LCK 0 affinity chromatography technology, affinity chromatography technology Wu J (2006), Wu J (2006) 2
LCK 0 LAT 0 biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology Munoz P (2003), Munoz P (2003), Jiang Y (2007), Jiang Y (2007) 4
CD247 1 DOCK2 3 affinity chromatography technology, imaging technique Nishihara H (2002), Chen TC (2014) 2
CD38 0 CD247 1 affinity chromatography technology, biochemical Munoz P (2003), Munoz P (2003) 2
LY6E 1 CD247 1 affinity chromatography technology Kosugi A (1998) 1
STAT5A 4 CBL 7 affinity chromatography technology, two hybrid Dieudonne FX (2013), Grossmann A (2015) 2
PTPN22 3 CSK 3 bioid, affinity chromatography technology St-Denis N (2016), Li X (2016) 2
CD247 1 RNF41 2 affinity chromatography technology, affinity chromatography technology Yang M (2015), Yang M (2015) 2
CBL 7 ZAP70 5 affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017) 11
GAB2 3 CD247 1 affinity chromatography technology Yamasaki S (2001) 1
PTPN22 3 CBL 7 affinity chromatography technology Cohen S (1999) 1
CD3E 0 JAK3 3 affinity chromatography technology Tomita K (2001) 1
TUBA1B 0 ZAP70 5 affinity chromatography technology Serrador JM (2004) 1
CD247 1 PCGF2 3 two hybrid Wang J (2011) 1
LAT 0 CBL 7 affinity chromatography technology Jiang Y (2007) 1
STAT5B 3 CD247 1 affinity chromatography technology Welte T (1999) 1
SLA 2 LAT 0 affinity chromatography technology Tang J (1999) 1
STAT5A 4 STAT5B 3 affinity chromatography technology Huttlin EL (2017) 1
LCK 0 UNC119 4 affinity chromatography technology, pull down Gorska MM (2004), Gorska MM (2004) 2
CD247 1 VTN 1 two hybrid Wang J (2011) 1
LCK 0 ZAP70 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Pelosi M (1999), Thome M (1995), Lupher ML (1996) 3
JAK3 3 STAT5B 3 two hybrid Fujitani Y (1997) 1
CD247 1 JAK3 3 affinity chromatography technology, pull down Tomita K (2001), Tomita K (2001) 2
CD247 1 LCK 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Munoz P (2003), Munoz P (2003), Yang M (2015) 3
CD247 1 ZNF281 1 two hybrid Wang J (2011) 1
LCK 0 CBL 7 affinity chromatography technology, pull down, pull down, affinity chromatography technology Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005) 4
GAB2 3 PIK3R1 6 affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down Lynch DK (2002), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Ren SY (2005), Momose H (2003) 6
STAT5A 4 CD247 1 affinity chromatography technology Welte T (1999) 1
ZAP70 5 LAT 0 enzymatic study, enzymatic study, imaging technique, affinity chromatography technology Paz PE (2001), Perez-Villar JJ (2002), Houtman JC (2006), Xie JJ (2013) 4
RNF41 2 ZAP70 5 affinity chromatography technology, pull down Yang M (2015), Yang M (2015) 2
CBL 7 PIK3R1 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015) 61
CSK 3 ZAP70 5 pull down Catipovic B (1996) 1
CD38 0 ZAP70 5 biochemical Munoz P (2003) 1
PTPN22 3 ZAP70 5 affinity chromatography technology, affinity chromatography technology Wu J (2006), Wu J (2006) 2
UNC119 4 CD247 1 affinity chromatography technology, pull down Gorska MM (2004), Gorska MM (2004) 2
CD247 1 TRAT1 0 affinity chromatography technology Kirchgessner H (2001) 1
CD247 1 ZAP70 5 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Mustelin T (1995), Wang HY (2001), La Face DM (1997), Huang H (2010), Huang H (2010), Hubert P (1996), Yang M (2015) 7
PIK3R1 6 TUBA1B 0 affinity chromatography technology, pull down Kapeller R (1995), Kapeller R (1995) 2
ZAP70 5 CD3E 0 pull down, affinity chromatography technology Bu JY (1995), Hubert P (1996) 2
PIK3R1 6 CD247 1 affinity chromatography technology Fang D (2001) 1
SLA2 1 ZAP70 5 affinity chromatography technology Pandey A (2002) 1
CBL 7 SLA 2 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Tang J (1999), Myers MD (2006), Sirvent A (2008), Swaminathan G (2007) 4
PTPN22 3 CD3E 0 affinity chromatography technology, affinity chromatography technology Wu J (2006), Wu J (2006) 2
SLA 2 CD247 1 affinity chromatography technology Tang J (1999) 1
PTPRC 1 CD247 1 pull down Furukawa T (1994) 1
CD3E 0 CD247 1 affinity chromatography technology, affinity chromatography technology, imaging technique Munoz P (2003), Munoz P (2003), Chen TC (2014) 3
CD38 0 LCK 0 affinity chromatography technology Munoz P (2003) 1
CD38 0 CD3E 0 affinity chromatography technology, biochemical Munoz P (2003), Munoz P (2003) 2
CBL 7 CD247 1 affinity chromatography technology, affinity chromatography technology Wang HY (2001), Wang HY (2001) 2
SLA2 1 CD247 1 affinity chromatography technology Pandey A (2002) 1
GAB2 3 LAT 0 affinity chromatography technology Yamasaki S (2001) 1
LAT 0 CD247 1 affinity chromatography technology Munoz P (2003) 1
CBL 7 CD38 0 fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe Shen M (2009), Shen M (2008), Shen M (2008) 3
SLA2 1 CBL 7 affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Pandey A (2002), Pandey A (2002), Pakuts B (2007), Pakuts B (2007), Holland SJ (2001), Manes GA (2006), Loreto MP (2003), Loreto MP (2003) 8
GAB2 3 ZAP70 5 affinity chromatography technology Yamasaki S (2001) 1
ICK 1 CD247 1 affinity chromatography technology August A (1996) 1
CBL 7 CSK 3 affinity chromatography technology, affinity chromatography technology Sanjay A (2001), Brehme M (2009) 2
CSK 3 CD247 1 pull down, affinity chromatography technology Catipovic B (1996), Catipovic B (1996) 2
LAT 0 CD3E 0 affinity chromatography technology Munoz P (2003) 1
PIK3R1 6 ZAP70 5 affinity chromatography technology Moon KD (2005) 1