PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	RECQL5	3	genetic interference	Xie L (2013)	1
RECQL5	3	MAPK8IP1	7	two hybrid	Stelzl U (2005)	1
PLK1	0	BRCA2	6	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Lee M (2004), Lin HR (2003), Lin HR (2003), Park I (2017)	4
MDC1	8	RAD50	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Xu X (2003), Goldberg M (2003), Goldberg M (2003), Stewart GS (2003), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	7
CUL5	1	POLR2I	0	affinity chromatography technology	Bennett EJ (2010)	1
WWP2	7	POLR2C	0	affinity chromatography technology	Chaudhary N (2014)	1
RECQL5	3	MCM7	5	affinity chromatography technology	Zheng L (2009)	1
RECQL5	3	25885	0	affinity chromatography technology	Urban V (2016)	1
BRCA1	7	RAD50	3	biochemical, biochemical, two hybrid, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Zhong Q (1999), Greenberg RA (2006), Chen L (2008), Hill SJ (2014), Acharya S (2014)	10
RPRD1B	1	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
25885	0	POLR2E	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
CREB1	1	TP53	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Giebler HA (2000), Giebler HA (2000), Giebler HA (2000), Okoshi R (2011), Borger DR (2006), Chen TC (2014)	6
RECQL5	3	RECQL4	5	affinity chromatography technology	Zheng L (2009)	1
CUL5	1	5430	0	affinity chromatography technology	Bennett EJ (2010)	1
POLR2M	0	POLR2F	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2D	0	POLR2G	0	pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
UBR5	13	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ling S (2011), Ling S (2011), Ling S (2011), Fogeron ML (2013), Flack JE (2017)	5
POLR2F	1	POLR2E	0	pull down, biochemical, affinity chromatography technology	Acker J (1997), Wan C (2015), Hein MY (2015)	3
BRCA1	7	EEF1G	0	affinity chromatography technology	Ertych N (2016)	1
DXO	4	POLR2M	0	affinity chromatography technology	Huttlin EL (2017)	1
POLR2B	3	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
RPRD1B	1	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2B	3	POLR2E	0	pull down, pull down, biochemical, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Wan C (2015)	4
BRCA1	7	25885	0	affinity chromatography technology	Johnston R (2016)	1
RPRD1B	1	POLR2M	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PLK1	0	TP53	0	enzymatic study	Dias SS (2009)	1
LMO2	2	RPRD1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL5	1	RECQL5	3	affinity chromatography technology	Bennett EJ (2010)	1
KIN	0	EIF2D	0	biochemical	Wan C (2015)	1
RECQL5	3	FANCC	0	genetic interference	Hosono Y (2014)	1
PRKDC	12	MRE11	3	unspecified method	Kim ST (1999)	1
RECQL5	3	DHX36	3	biochemical	Wan C (2015)	1
TOP3A	0	BRCA2	6	genetic interference	Srivas R (2016)	1
RAD51	3	EIF2D	0	affinity chromatography technology	Ewing RM (2007)	1
RECQL5	3	ITGB3BP	0	two hybrid	Stelzl U (2005)	1
POLR2C	0	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
RECQL5	3	PLK1	0	two hybrid	Stelzl U (2005)	1
RECQL5	3	RAD50	3	affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009)	3
RPRD1B	1	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LMO2	2	POLR2B	3	affinity chromatography technology	Huttlin EL (2017)	1
POLR2G	0	POLR2F	1	pull down, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Huttlin EL (2015), Hein MY (2015)	3
MDC1	8	POLR2E	0	affinity chromatography technology	Woods NT (2012)	1
MDC1	8	NCL	1	pull down	Kobayashi J (2012)	1
POLR2C	0	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Ayguen O (2008)	2
MDC1	8	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, pull down, affinity chromatography technology, imaging technique	Xu X (2003), Goldberg M (2003), Goldberg M (2003), Lukas C (2004), Cha H (2010), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Lou Z (2004), Hari FJ (2010), Lu CS (2012), Wu L (2008), Wu L (2008), Wu L (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	18
HIST1H3A	3	CREB1	1	affinity chromatography technology	Sun HS (2003)	1
BRCA1	7	RPRD1B	1	affinity chromatography technology	Woods NT (2012)	1
RECQL5	3	EIF2D	0	biochemical	Wan C (2015)	1
CUL5	1	MCM7	5	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
BRCA1	7	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Dong Y (2003), Dong Y (2003), Dong Y (2003), Wang Q (2001), Chen J (1998), Mok MT (2010), Scully R (1997), Scully R (1997), Johnson N (2013), Jung YS (2014), Jung YS (2014), Parameswaran B (2015)	13
BRCA2	6	PCNA	0	affinity chromatography technology	Brough R (2012)	1
POLR2B	3	25885	0	biochemical	Wan C (2015)	1
CUL5	1	POLR2C	0	affinity chromatography technology	Bennett EJ (2010)	1
BRCA2	6	TP53	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Marmorstein LY (1998)	4
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
BRCA1	7	NCL	1	affinity chromatography technology	Ertych N (2016)	1
LMO2	2	POLR2F	1	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	POLR2I	0	affinity chromatography technology	Woods NT (2012)	1
5430	0	POLR2C	0	pull down, pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	6
RECQL5	3	CREB1	1	two hybrid	Stelzl U (2005)	1
LMO2	2	POLR2D	0	affinity chromatography technology	Huttlin EL (2017)	1
RPRD1B	1	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PLK1	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Zou J (2013), Zou J (2014)	2
WWP2	7	POLR2E	0	affinity chromatography technology	Chaudhary N (2014)	1
POLR2C	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
POLR2F	1	25885	0	biochemical, affinity chromatography technology, affinity chromatography technology	Wan C (2015), Hein MY (2015), Hein MY (2015)	3
BRCA1	7	CREB1	1	genetic interference	Houvras Y (2000)	1
RECQL5	3	RAD51	3	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Ayguen O (2008)	2
BRCA2	6	RAD51	3	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sharan SK (1997), Lin HR (2003), Yu DS (2003), Yu DS (2003), Chen PL (1998), Chen PL (1998), Chen PL (1998), Dong Y (2003), Dong Y (2003), Dong Y (2003), Sarkisian CJ (2001), Wong AK (1997), Wong AK (1997), Katagiri T (1998), Katagiri T (1998), Pellegrini L (2002), Tarsounas M (2004), Liu J (2001), Chen J (1998), Sharan SK (1997), Marmorstein LY (1998), Ohashi A (2005), Shivji MK (2006), Xia B (2006), Xia B (2006), Badie S (2010), Liu J (2010), Carreira A (2011), Chen CF (1999), Chen CF (1999), Chen CF (1999), Lee M (2011), Esashi F (2005), Esashi F (2005), Esashi F (2005), Thorslund T (2007), Thorslund T (2007), Esashi F (2007), Brough R (2012), Zhao W (2015), Chu WK (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Trego KS (2016), Luo K (2016)	46
PRKDC	12	TP53	0	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim ST (1999), Goudelock DM (2003), Yavuzer U (1998), Maiti AK (2010), Shieh SY (1997), Chan DW (2000), Kim ST (1999), Sakaguchi K (1998), Borcherds W (2014)	9
MDC1	8	RECQL5	3	affinity chromatography technology	Woods NT (2012)	1
RECQL5	3	TOP3B	5	affinity chromatography technology	Shimamoto A (2000)	1
CUL5	1	POLR2B	3	affinity chromatography technology	Bennett EJ (2010)	1
RECQL5	3	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Zheng L (2009), Ayguen O (2008)	2
LMO2	2	POLR2I	0	affinity chromatography technology	Huttlin EL (2017)	1
NBN	1	PRKDC	12	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
5430	0	POLR2E	0	pull down, pull down, pull down, biochemical, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Knuesel MT (2009), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	6
RECQL5	3	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2017)	2
POLR2B	3	POLR2C	0	pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	5
DHX29	2	RECQL5	3	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
5430	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Wan C (2015), Hein MY (2015)	4
8339	0	RECQL5	3	bioid	Lambert JP (2015)	1
POLR2C	0	POLR2E	0	pull down, pull down, biochemical, affinity chromatography technology, biochemical	Acker J (1997), Acker J (1997), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	5
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
RPRD1B	1	POLR2F	1	affinity chromatography technology	Huttlin EL (2015)	1
RPRD1B	1	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2M	0	POLR2D	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FOSL2	2	RECQL5	3	affinity chromatography technology	Hein MY (2015)	1
POLR2M	0	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WWP2	7	RECQL5	3	affinity chromatography technology	Chaudhary N (2014)	1
RECQL5	3	PRKDC	12	affinity chromatography technology	Zheng L (2009)	1
POLR2D	0	POLR2E	0	pull down, biochemical, affinity chromatography technology	Schaller S (1999), Wan C (2015), Huttlin EL (2017)	3
NBN	1	RAD50	3	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Desai-Mehta A (2001), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Greenberg RA (2006), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015)	17
POLR2C	0	POLR2F	1	pull down, pull down, biochemical, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015)	4
POLR2G	0	POLR2I	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
POLR2E	0	POLR2I	0	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
PCNA	0	PRKDC	12	affinity chromatography technology	Ohta S (2002)	1
TP53	0	NCL	1	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down	Daniely Y (2002), Daniely Y (2002), Daniely Y (2002), Lim KH (2015)	4
BRCA1	7	POLR2G	0	affinity chromatography technology	Woods NT (2012)	1
POLR2M	0	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
RECQL5	3	BRCA2	6	genetic interference	Hosono Y (2014)	1
5430	0	POLR2G	0	pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Knuesel MT (2009), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
PCNA	0	RAD51	3	affinity chromatography technology, imaging technique	Chen X (2016), Sato K (2016)	2
RECQL5	3	UBR5	13	affinity chromatography technology	Zheng L (2009)	1
POLR2B	3	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
CUL5	1	NCL	1	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	POLR2D	0	affinity chromatography technology	Woods NT (2012)	1
POLR2B	3	POLR2F	1	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
MDC1	8	TP53	0	affinity chromatography technology	Xu X (2003)	1
MRE11	3	RAD50	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Chiba N (2001), Chiba N (2001), Dolganov GM (1996), Dolganov GM (1996), Trujillo KM (1998), Goedecke W (1999), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Cho YW (2007), Greenberg RA (2006), Alt JR (2005), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Wijnhoven P (2015), Boldt K (2016), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015), Nicholson J (2017)	25
WWP2	7	PCNA	0	affinity chromatography technology	Chaudhary N (2014)	1
PRKDC	12	HIST1H3A	3	imaging technique	Olsen BB (2012)	1
CUL5	1	POLR2D	0	affinity chromatography technology	Bennett EJ (2010)	1
RECQL5	3	PCNA	0	affinity chromatography technology	Ayguen O (2008)	1
HIST1H3A	3	RECQL5	3	bioid	Lambert JP (2015)	1
RECQL5	3	POLR2I	0	affinity chromatography technology	Ayguen O (2008)	1
CUX1	7	RECQL5	3	two hybrid	Stelzl U (2005)	1
MDC1	8	POLR2B	3	affinity chromatography technology	Woods NT (2012)	1
RECQL5	3	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2017)	2
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
POLR2M	0	POLR2B	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPRD1B	1	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RECQL5	3	NCL	1	affinity chromatography technology	Zheng L (2009)	1
RECQL5	3	NBN	1	affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009)	3
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
POLR2M	0	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	POLR2C	0	affinity chromatography technology	Woods NT (2012)	1
POLR2M	0	5430	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	MCM7	5	affinity chromatography technology, biochemical	Kang H (2011), Yankulov K (1999)	2
EEF1G	0	RECQL5	3	two hybrid, two hybrid	Stelzl U (2005), Stelzl U (2005)	2
LMO2	2	POLR2C	0	affinity chromatography technology	Huttlin EL (2017)	1
RECQL5	3	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zheng L (2009), Zheng L (2009), Zheng L (2009), Zheng L (2009)	4
LMO2	2	RECQL5	3	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
POLR2F	1	POLR2I	0	biochemical, affinity chromatography technology	Wan C (2015), Hein MY (2015)	2
MDC1	8	5430	0	unspecified method, affinity chromatography technology	Rodriguez M (2003), Woods NT (2012)	2
LMO2	2	POLR2G	0	affinity chromatography technology	Huttlin EL (2017)	1
RECQL5	3	DDX42	3	two hybrid	Stelzl U (2005)	1
POLR2F	1	RECQL5	3	affinity chromatography technology	Hein MY (2015)	1
NCL	1	NBN	1	pull down	Kobayashi J (2012)	1
POLR2M	0	POLR2I	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2D	0	POLR2C	0	pull down, biochemical, affinity chromatography technology, biochemical	Schaller S (1999), Havugimana PC (2012), Ayguen O (2008), Wan C (2015)	4
POLR2D	0	POLR2B	3	pull down, biochemical, biochemical, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	4
WWP2	7	POLR2D	0	affinity chromatography technology	Chaudhary N (2014)	1
LMO2	2	POLR2E	0	affinity chromatography technology	Huttlin EL (2017)	1
LMO2	2	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
BNIPL	9	RECQL5	3	two hybrid	Wang J (2011)	1
MDC1	8	POLR2C	0	affinity chromatography technology	Woods NT (2012)	1
HIST1H3A	3	MCM7	5	affinity chromatography technology	Huttlin EL (2017)	1
5430	0	PCNA	0	affinity chromatography technology	Kang H (2011)	1
RECQL5	3	MTSS1	1	two hybrid	Stelzl U (2005)	1
BRCA1	7	POLR2M	0	affinity chromatography technology	Woods NT (2012)	1
HIST1H3A	3	NBN	1	affinity chromatography technology	Fnu S (2011)	1
POLR2D	0	5430	0	pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Schaller S (1999), Havugimana PC (2012), Wan C (2015), Zhao DY (2016), Huttlin EL (2017)	5
KIN	0	PCNA	0	affinity chromatography technology, affinity chromatography technology	Miccoli L (2005), Miccoli L (2005)	2
5430	0	POLR2I	0	pull down, biochemical, biochemical	Knuesel MT (2009), Havugimana PC (2012), Wan C (2015)	3
POLR2D	0	POLR2I	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
MDC1	8	RAD51	3	affinity chromatography technology, affinity chromatography technology, pull down	Zhang J (2005), Zhang J (2005), Zhang J (2005)	3
PITHD1	1	RECQL5	3	affinity chromatography technology	Huttlin EL (2017)	1
RECQL5	3	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Zheng L (2009), Ayguen O (2008), Ayguen O (2008), Ayguen O (2008), Ayguen O (2008), Urban V (2016), Kanagaraj R (2010), Kanagaraj R (2010), Li M (2011)	9
CUL5	1	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	FOSL2	2	affinity chromatography technology	Hill SJ (2014)	1
MDC1	8	MRE11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology	Xu X (2003), Xu X (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Stewart GS (2003), Chapman JR (2008), Chapman JR (2008), Chapman JR (2008)	10
RPRD1B	1	POLR2C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KIN	0	RECQL5	3	biochemical	Wan C (2015)	1
DXO	4	RECQL5	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
POLR2E	0	POLR2G	0	pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Acker J (1997), Acker J (1997), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
NCL	1	POLR2B	3	affinity chromatography technology	Salvetti A (2016)	1
RAD51	3	TP53	0	affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Stuerzbecher HW (1996), Stuerzbecher HW (1996), Buchhop S (1997), Nakai-Murakami C (2007), Yang Q (2004), Rasti M (2015), Rasti M (2015)	10
RECQL5	3	TOP3A	0	affinity chromatography technology	Shimamoto A (2000)	1
WWP2	7	EEF1G	0	affinity chromatography technology	Chaudhary N (2014)	1
PCNA	0	MCM7	5	affinity chromatography technology	Han J (2014)	1
RECQL5	3	POLR2G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ayguen O (2008), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
CREB1	1	5430	0	affinity chromatography technology	Li X (2015)	1
POLR2M	0	POLR2E	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	RECQL5	3	affinity chromatography technology	Woods NT (2012)	1
8339	0	BRCA1	7	bioid	Lambert JP (2015)	1
WWP2	7	POLR2M	0	affinity chromatography technology	Chaudhary N (2014)	1
PARD6B	0	RECQL5	3	affinity chromatography technology	Hein MY (2015)	1
WWP2	7	5430	0	affinity chromatography technology	Huttlin EL (2017)	1
TIMP1	0	RECQL5	3	two hybrid	Stelzl U (2005)	1
BRCA1	7	POLR2E	0	affinity chromatography technology	Woods NT (2012)	1
MDC1	8	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, imaging technique, imaging technique	Matsuoka S (2007), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Lou Z (2003), Mok MT (2010), Au WW (2005)	7
RPRD1B	1	POLR2G	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5430	0	POLR2B	3	pull down, biochemical, biochemical	Knuesel MT (2009), Havugimana PC (2012), Wan C (2015)	3
CUL5	1	PRKDC	12	affinity chromatography technology	Bennett EJ (2010)	1