Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CHST3 9469 DOCETAXEL CHEMBL92 PharmGKB
CHST3 9469 THALIDOMIDE CHEMBL468 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CHST3 rs4148943 C docetaxel efficacy yes (allele inferred by frequency comparison with data in pgkb, actual base not listed in paper) Allele C is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele T. 20038957 655388254
CHST3 rs730720 C docetaxel efficacy yes (allele inferred by frequency comparison with dbSNP, actual base not listed in paper, since frequencies are close have low confidence in this allele assignment) Allele C is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele T. 20038957 699638963
CHST3 rs4148945 C docetaxel efficacy yes (allele inferred by frequency comparison with data in pgkb, actual base not listed in paper) Allele C is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele T. 20038957 655388257
CHST3 rs4148947 T docetaxel efficacy yes (allele inferred by frequency comparison with dbSNP, actual base not listed in paper, since frequencies are close have low confidence in this allele assignment) Allele T is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele C. 20038957 699638975
CHST3 rs4148950 A docetaxel efficacy yes (allele inferred by frequency comparison with dbSNP, actual base not listed in paper) Allele A is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele G. 20038957 699638971
CHST3 rs12418 A docetaxel efficacy yes (allele inferred by frequency comparison with dbSNP, actual base not listed in paper) Allele A is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele G. 20038957 655388216
CHST3 rs1871450 A docetaxel efficacy yes (allele inferred by frequency comparison with data in pgkb, actual base not listed in paper) Allele A is associated with increased response to docetaxel and thalidomide in people with Prostatic Neoplasms as compared to allele G. 20038957 655388232