Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ATG5	rs9373839	CC + CT	adalimumab	efficacy	yes	Treatment protocol was 160 mg of adalimumab at week zero, 80 mg at week 2, and a maintenance dose of 40 mg every other week. Response measured with the Inflammatory Bowel Disease Questionnaire (IBDQ) score, with IBDQ score higher than 170 or an increase of at least 22 points.	Genotypes CC + CT are associated with increased response to adalimumab in people with Inflammatory Bowel Diseases as compared to genotype TT.	27096233	1447988330
ATG5	rs510432	CT + TT	adalimumab	efficacy	yes	Alleles given as A and G. Treatment protocol was 160 mg of adalimumab at week zero, 80 mg at week 2, and a maintenance dose of 40 mg every other week. Response measured with the CRP level, with CRP reduction of 25% from baseline of <3mg/L considered a positive response.	Genotypes CT + TT are associated with increased response to adalimumab in people with Inflammatory Bowel Diseases as compared to genotype CC.	27096233	1447988337