PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ITGAV	7	PTK2	2	affinity chromatography technology, affinity chromatography technology	Lee DY (2010), Avraham HK (2003)	2
PTPN12	2	PTK2B	6	enzymatic study	Lyons PD (2001)	1
CBL	7	HSPA5	0	affinity chromatography technology, affinity chromatography technology	Valiya Veettil M (2011), Brehme M (2009)	2
CBL	7	HCK	5	affinity chromatography technology, enzymatic study, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, unspecified method	Howlett CJ (2002), Howlett CJ (1999), Howlett CJ (1999), Howlett CJ (1999), Howlett CJ (1999), Anderson SM (1997), Liu BA (2012)	7
BCAR1	6	VPS11	3	two hybrid	Stelzl U (2005)	1
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
SH3KBP1	1	INPPL1	6	affinity chromatography technology	Havrylov S (2009)	1
SFN	1	ABL1	9	affinity chromatography technology	Raina D (2006)	1
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
TRIM25	5	ZYX	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	MAPK14	0	affinity chromatography technology	Choudhury NR (2017)	1
PTEN	24	PXN	1	affinity chromatography technology	Haier J (2002)	1
HNRNPL	3	TNK2	7	affinity chromatography technology	Fei T (2017)	1
MAPK14	0	PTPN11	20	biochemical	Kristensen AR (2012)	1
ERBB2	6	CRK	0	unspecified method	Jones RB (2006)	1
PTK2B	6	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Manie SN (1997), Anfosso F (2001), Astier A (1997), Takahashi T (2003)	4
NEDD9	3	BCAR1	6	affinity chromatography technology	Law SF (1999)	1
PTPN12	2	EPN1	4	biochemical	Kristensen AR (2012)	1
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
NPHP1	2	HYOU1	2	bioid	Gupta GD (2015)	1
YWHAZ	1	HNRNPL	3	affinity chromatography technology	Ewing RM (2007)	1
CBL	7	NCK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Erdreich-Epstein A (1999), Miyoshi-Akiyama T (2001), Izadi KD (1998), Izadi KD (1998), Wunderlich L (1999), Shishido T (2000), Okabe S (2006), Adler CE (2000), Adler CE (2000), Buvall L (2013), Buvall L (2013), Buvall L (2013), Buvall L (2013)	13
ITGAV	7	PXN	1	affinity chromatography technology	Elsegood CL (2006)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
HNRNPL	3	BCAR1	6	affinity chromatography technology	Fei T (2017)	1
TNK2	7	LYN	2	pull down, affinity chromatography technology	Chan W (2011), Chan W (2011)	2
TRIM25	5	ARHGAP32	11	affinity chromatography technology	Choudhury NR (2017)	1
PTPN1	2	GRB2	2	pull down, pull down, affinity chromatography technology	Goldstein BJ (2000), Liu F (1996), Li X (2016)	3
PXN	1	PTK2B	6	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hiregowdara D (1997), Hiregowdara D (1997), Matsuya M (1998), Matsuya M (1998), Anfosso F (2001), Ivankovic-Dikic I (2000)	6
TSG101	1	CRK	0	affinity chromatography technology, imaging technique	Kumar B (2016), Kumar B (2016)	2
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
SH2D3C	2	NEDD9	3	affinity chromatography technology	Sakakibara A (2000)	1
INPPL1	6	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
PXN	1	NEDD9	3	affinity chromatography technology	Zhang Z (1999)	1
PTK2B	6	FYN	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ganju RK (1997), Katagiri T (2000), Qian D (1997), Qian D (1997), Marie-Cardine A (1999)	5
CRKL	1	NEDD9	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kyono WT (1998), Manie SN (1997), Astier A (1997), Sattler M (1997), Sattler M (1997)	5
BMX	0	SRC	2	affinity chromatography technology	Tsai YT (2000)	1
CRKL	1	PXN	1	affinity chromatography technology, pull down, affinity chromatography technology	Salgia R (1995), Salgia R (1995), Nishiya N (2001)	3
MAPK8	3	BCAR1	6	affinity chromatography technology	Girardin SE (2001)	1
SH3KBP1	1	ABL1	9	affinity chromatography technology	Havrylov S (2009)	1
ESR1	0	SFN	1	affinity chromatography technology	Tarallo R (2011)	1
EPN1	4	BCAR1	6	biochemical	Kristensen AR (2012)	1
HCK	5	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
BCAR1	6	PTPN12	2	affinity chromatography technology, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology, bioid	Lin Y (2003), Garton AJ (1997), Garton AJ (1997), Garton AJ (1997), Cote JF (1998), Cote JF (1998), Garton AJ (1996), Garton AJ (1996), St-Denis N (2016)	9
SFN	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yang HY (2007), Yang HY (2007), Yang HY (2007), Wood NT (2009)	4
ITGAV	7	CBL	7	affinity chromatography technology	Elsegood CL (2006)	1
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
CBL	7	ABL1	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, far western blotting, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Soubeyran P (2003), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Patel H (2006), Johnson KJ (2009), Shishido T (2000), Shishido T (2000), Shishido T (2000), Gaston I (2004), Jain SK (1997), Reedquist KA (1996), Bhat A (1997), Bhat A (1997), Bhat A (1997), Grossmann AH (2004), Brehme M (2009), Brehme M (2009), Brehme M (2009), Nishihara T (2003), Tsukahara F (2010)	21
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
TRIM25	5	SFN	1	affinity chromatography technology	Urano T (2002)	1
SH3KBP1	1	CRK	0	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
PTPRH	0	BCAR1	6	pull down	Noguchi T (2001)	1
ZYX	2	PXN	1	biochemical	Kristensen AR (2012)	1
YWHAE	0	MAPK14	0	biochemical	Wan C (2015)	1
BCAR1	6	RAN	1	two hybrid	Plafker SM (2000)	1
INPPL1	6	PIK3R1	6	affinity chromatography technology	Brehme M (2009)	1
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
ARHGAP32	11	PIK3R1	6	affinity chromatography technology	Moon SY (2003)	1
PTK2	2	MDM2	2	pull down	Lim ST (2008)	1
PXN	1	FYN	1	affinity chromatography technology	Chen LM (2000)	1
HSPA5	0	SFN	1	biochemical	Wan C (2015)	1
SH3KBP1	1	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Tibaldi EV (2003)	3
EFS	2	CRK	0	far western blotting	Alexandropoulos K (1996)	1
HNRNPL	3	PTK2	2	affinity chromatography technology	Fei T (2017)	1
ESR1	0	HSPA5	0	affinity chromatography technology	Dhamad AE (2016)	1
YWHAZ	1	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), Yoshida K (2005), So J (2015)	5
BCAR1	6	BMX	0	unspecified method	Liu BA (2012)	1
PTK2B	6	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Sanjay A (2001), Schmidt MH (2003)	4
NEDD9	3	FYN	1	affinity chromatography technology	Tachibana K (1997)	1
PTPN12	2	PXN	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, bioid, affinity chromatography technology	Shen Y (2000), Shen Y (2000), Shen Y (2000), Cote JF (1999), Cote JF (1999), Shen Y (1998), Shen Y (1998), St-Denis N (2016), Huttlin EL (2017)	9
INPPL1	6	BCAR1	6	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, far western blotting, pull down	Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001)	6
SFN	1	ARHGAP32	11	affinity chromatography technology	Benzinger A (2005)	1
TSG101	1	BCAR1	6	affinity chromatography technology, imaging technique	Kumar B (2016), Kumar B (2016)	2
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
HNRNPL	3	SRC	2	affinity chromatography technology	Fei T (2017)	1
MAPK8	3	YWHAZ	1	enzymatic study	Yoshida K (2005)	1
HYOU1	2	BCAR1	6	biochemical	Kristensen AR (2012)	1
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
EFS	2	SRC	2	unspecified method, unspecified method, affinity chromatography technology	Alexandropoulos K (1996), Alexandropoulos K (1996), Alexandropoulos K (1996)	3
PTK2	2	SH3KBP1	1	affinity chromatography technology	Schmidt MH (2003)	1
PTK2B	6	GRB2	2	affinity chromatography technology, affinity chromatography technology	Blaukat A (1999), Bruzzaniti A (2009)	2
NEDD9	3	ABL1	9	affinity chromatography technology, affinity chromatography technology	Minegishi M (1996), Law SF (1996)	2
SRC	2	PTPN1	2	enzymatic study, affinity chromatography technology	Jung EJ (1998), Ragab A (2003)	2
ALK	8	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004), Bai RY (1998), Ambrogio C (2005), Ambrogio C (2005)	5
SH2D3C	2	EFS	2	two hybrid	Rual JF (2005)	1
NEDD9	3	PTK2	2	affinity chromatography technology, two hybrid	Law SF (1996), Law SF (1996)	2
YWHAE	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Subramanian RR (2001), Taipale M (2014), Taipale M (2014)	3
ALK	8	PXN	1	affinity chromatography technology	Ambrogio C (2005)	1
SH2D3C	2	BCAR1	6	affinity chromatography technology	Sakakibara A (2000)	1
RAN	1	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
ABL1	9	HCK	5	affinity chromatography technology	Warmuth M (1997)	1
NPHP1	2	ARHGAP32	11	two hybrid, two hybrid	Eley L (2008), Eley L (2008)	2
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
TRIM25	5	CBL	7	affinity chromatography technology	Choudhury NR (2017)	1
PTK2	2	DOCK1	14	affinity chromatography technology	Hsia DA (2003)	1
TSG101	1	MDM2	2	affinity chromatography technology, affinity chromatography technology	Li L (2001), Cheng TH (2007)	2
CDC42	3	BCAR1	6	affinity chromatography technology	Modzelewska K (2006)	1
CRK	0	DOCK1	14	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Hsia DA (2003), Hsia DA (2003), Hsia DA (2003), Nishihara H (1999), Hasegawa H (1996), Hasegawa H (1996), Gu J (2001), Matsuda M (1996), Wu Y (2005), Wan C (2015)	10
BCAR1	6	PTPN11	20	affinity chromatography technology	Manie SN (1997)	1
HNRNPL	3	YWHAE	0	biochemical, affinity chromatography technology	Wan C (2015), Fei T (2017)	2
FYN	1	ARHGAP32	11	two hybrid, pull down, affinity chromatography technology	Taniguchi S (2003), Taniguchi S (2003), Taniguchi S (2003)	3
CRK	0	SFN	1	affinity chromatography technology	Brehme M (2009)	1
SRC	2	PTK2B	6	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Keely SJ (2000), Kumar S (1999), Dikic I (1996), Dikic I (1996), Bruzzaniti A (2009)	5
YWHAZ	1	SFN	1	biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2015), Huttlin EL (2017)	3
ERBB2	6	BMX	0	unspecified method	Jones RB (2006)	1
NCK1	0	PTK2	2	pull down, affinity chromatography technology, pull down	Minegishi M (1996), Goicoechea SM (2002), Goicoechea SM (2002)	3
LYN	2	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
CRK	0	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Moon SY (2003)	3
NEDD9	3	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Minegishi M (1996), Ohashi Y (1998), Ohashi Y (1998), Ohashi Y (1998), Kanda H (1997)	5
PTPRH	0	PXN	1	pull down	Noguchi T (2001)	1
GRB2	2	YWHAZ	1	affinity chromatography technology	Bisson N (2011)	1
ERBB2	6	GMPR2	1	two hybrid	Arroyo R (2015)	1
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
CRKL	1	PTPN11	20	affinity chromatography technology	Chin H (1997)	1
CRK	0	INPPL1	6	affinity chromatography technology	Brehme M (2009)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
CBL	7	PXN	1	affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Salgia R (1996)	2
FYN	1	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Tang H (1999), Chernock RD (2001)	2
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
BCAR1	6	NPHP1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Donaldson JC (2000), Donaldson JC (2000), Benzing T (2001), Eley L (2008), Eley L (2008), Eley L (2008)	6
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
HCK	5	MDM2	2	unspecified method	Batuello CN (2015)	1
PTK2	2	FYN	1	affinity chromatography technology, x-ray crystallography	Messina S (2003), Arold ST (2001)	2
BCAR1	6	HSPA5	0	two hybrid	Stelzl U (2005)	1
ERBB2	6	ITGAV	7	affinity chromatography technology, affinity chromatography technology	Lal S (2015), Lal S (2015)	2
NEDD9	3	LYN	2	pull down, affinity chromatography technology	Manie SN (1997), Manie SN (1997)	2
ESR1	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Castoria G (2001), Simoncini T (2000), Simoncini T (2000)	3
FYN	1	EFS	2	pull down, enzymatic study, two hybrid	Donlin LT (2002), Donlin LT (2002), Rolland T (2014)	3
BCAR1	6	TSEN34	2	biochemical	Kristensen AR (2012)	1
TRIM25	5	PTK2	2	affinity chromatography technology	Choudhury NR (2017)	1
SRC	2	LYN	2	unspecified method	Pirozzi G (1997)	1
SFN	1	BCAR1	6	affinity chromatography technology	Benzinger A (2005)	1
TRIP6	2	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Xu J (2004), Yi J (2002)	2
BCAR1	6	FXYD6	0	two hybrid	Stelzl U (2005)	1
CRK	0	RAPGEF1	6	affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka S (1994), Tanaka S (1994), Tanaka S (1994), Ingham RJ (1996), Sawasdikosol S (1995), Sawasdikosol S (1995), Brehme M (2009), Peterson ME (2008), Larsson H (1999)	9
TRIM25	5	PTPN11	20	affinity chromatography technology	Choudhury NR (2017)	1
PXN	1	NCK1	0	pull down	Turner CE (1999)	1
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
CBL	7	MAPK14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Erdreich-Epstein A (1997), Shen M (2009), Shen M (2009)	3
LCK	0	PTK2B	6	affinity chromatography technology	Ganju RK (1997)	1
VCL	6	SFN	1	biochemical	Kristensen AR (2012)	1
BCAR1	6	RAPGEF1	6	two hybrid, pull down, affinity chromatography technology	Kirsch KH (1998), Kirsch KH (1998), Kirsch KH (1998)	3
TSG101	1	CD2AP	0	affinity chromatography technology	Morita E (2007)	1
TRIM25	5	KIF13A	3	affinity chromatography technology	Choudhury NR (2017)	1
PTK2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Manes S (1999), Takahashi A (2011)	2
NEDD9	3	RAPGEF1	6	affinity chromatography technology	Astier A (1997)	1
NPHP1	2	CBL	7	bioid	Gupta GD (2015)	1
PIK3R1	6	SH3KBP1	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Gout I (2000), Tossidou I (2010), Borthwick EB (2004), Borthwick EB (2004)	4
PTK2B	6	NEDD9	3	affinity chromatography technology	Manie SN (1997)	1
SRC	2	MDM2	2	unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Batuello CN (2015), Batuello CN (2015), Batuello CN (2015), Batuello CN (2015), Batuello CN (2015)	5
ERBB2	6	PTPRH	0	affinity chromatography technology	Yao Z (2017)	1
TSEN34	2	ARMCX3	0	biochemical	Kristensen AR (2012)	1
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
TRIM25	5	MDM2	2	affinity chromatography technology	Choudhury NR (2017)	1
PTK2	2	SRC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hecker TP (2002), Angers-Loustau A (1999), Relou IA (2003), Messina S (2003), Lebrun P (1998), Ponnala S (2011), Grossmann A (2015), Chen TC (2014), Lee J (2013), Reiske HR (2000)	11
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
ABL1	9	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, enzymatic study, two hybrid, enzymatic study	Brehme M (2009), Brehme M (2009), Brehme M (2009), Peterson ME (2008), Yoshida K (2005), Chen C (2008), Feller SM (1994), Feller SM (1994), Bai RY (1998), Ren J (2002)	10
HCK	5	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
CDC42	3	CBL	7	affinity chromatography technology, pull down, affinity chromatography technology	Wu WJ (2003), Wu WJ (2003), Simmons A (2005)	3
ID2	0	NEDD9	3	affinity chromatography technology, two hybrid	Law SF (1999), Law SF (1999)	2
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
GRB2	2	TSG101	1	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Bisson N (2011)	2
BCAR1	6	DOCK1	14	pull down, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hsia DA (2003), Hsia DA (2003)	3
TRIM25	5	HNRNPL	3	affinity chromatography technology	Choudhury NR (2017)	1
SH2D3A	3	BCAR1	6	affinity chromatography technology	Lu Y (1999)	1
TRIM25	5	ITGAV	7	affinity chromatography technology	Choudhury NR (2017)	1
BCAR1	6	LCK	0	pull down	Manie SN (1997)	1
BCAR1	6	CD2AP	0	pull down, affinity chromatography technology	Kirsch KH (1999), Tibaldi EV (2003)	2
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
TRIP6	2	NEDD9	3	two hybrid, two hybrid, two hybrid	Yi J (2002), Rolland T (2014), Solaz-Fuster MC (2006)	3
BCAR1	6	TNS1	6	affinity chromatography technology	Salgia R (1996)	1
ZYX	2	CD2AP	0	biochemical	Wan C (2015)	1
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
ABL1	9	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Brehme M (2009), Brehme M (2009)	3
TRIP6	2	SRC	2	affinity chromatography technology	Xu J (2004)	1
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
PXN	1	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovacic-Milivojevic B (2001), Matsuya M (1998), Turner CE (1999), Liu S (2002), Liu S (2002), Mazaki Y (1997), Zheng C (1998), Brown MC (1996), Fujita H (1998), Zhang Z (1999), Wang JF (2000), Ivankovic-Dikic I (2000)	12
NPHP1	2	TNK2	7	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Eley L (2008), Eley L (2008), Eley L (2008), Eley L (2008), Chan W (2011)	5
ZYX	2	BCAR1	6	affinity chromatography technology	Yi J (2002)	1
MAPK8	3	CRK	0	affinity chromatography technology, pull down, imaging technique	Girardin SE (2001), Girardin SE (2001), Chen TC (2014)	3
LYN	2	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Manie SN (1997), Qiu W (1998)	2
BCAR3	5	NEDD9	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Cai D (2003), Rolland T (2014), Huttlin EL (2017)	3
BCAR1	6	FYN	1	two hybrid, affinity chromatography technology, pull down	Donaldson JC (2000), Manie SN (1997), Manie SN (1997)	3
MAPK14	0	MAPK8	3	affinity chromatography technology	Chan PM (2008)	1
PIK3R1	6	ALK	8	pull down	Ren SY (2005)	1
TRIM25	5	ABL1	9	affinity chromatography technology	Choudhury NR (2017)	1
CBL	7	PTEN	24	affinity chromatography technology, affinity chromatography technology	Rodriguez S (2013), Rodriguez S (2013)	2
TNK2	7	CRKL	1	affinity chromatography technology	Mahendrarajah N (2017)	1
TNK2	7	ALK	8	affinity chromatography technology	Pao-Chun L (2009)	1
GRB2	2	HSPA5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009)	2
SFN	1	SH2D3A	3	affinity chromatography technology	Benzinger A (2005)	1
SRC	2	SRCIN1	3	affinity chromatography technology, affinity chromatography technology, pull down	Di Stefano P (2007), Di Stefano P (2007), Di Stefano P (2007)	3
TRIM25	5	VCL	6	affinity chromatography technology	Choudhury NR (2017)	1
PTPN11	20	PTK2B	6	affinity chromatography technology, affinity chromatography technology, far western blotting, enzymatic study	Chauhan D (2000), Chauhan D (2000), Chauhan D (2000), Chauhan D (2000)	4
PTK2B	6	SH3KBP1	1	affinity chromatography technology	Schmidt MH (2003)	1
TRIM25	5	YWHAZ	1	affinity chromatography technology	Choudhury NR (2017)	1
YWHAZ	1	TNS1	6	two hybrid	Bandyopadhyay S (2010)	1
TRIP6	2	PXN	1	affinity chromatography technology	Xu J (2004)	1
BCAR1	6	EFS	2	two hybrid	Stelzl U (2005)	1
RAPGEF1	6	GRB2	2	affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology	Smit L (1996), Tanaka S (1994), Bandyopadhyay S (2010), Ingham RJ (1996)	4
DOCK1	14	SRC	2	affinity chromatography technology	Hsia DA (2003)	1
UHRF2	1	FYN	1	far western blotting	Mori T (2011)	1
SRC	2	PTPN11	20	enzymatic study	Vogel W (1996)	1
HCK	5	SRC	2	affinity chromatography technology	Howlett CJ (2002)	1
TRIM25	5	ESR1	0	affinity chromatography technology, pull down, enzymatic study	Nakajima A (2007), Nakajima A (2007), Nakajima A (2007)	3
TSG101	1	TRIM25	5	biochemical	Wan C (2015)	1
PTK2	2	LYN	2	affinity chromatography technology, two hybrid	Chung J (1997), Grossmann A (2015)	2
UHRF2	1	BCAR1	6	far western blotting	Mori T (2011)	1
BCAR1	6	MDM2	2	affinity chromatography technology	Kurokawa M (2013)	1
TSG101	1	CBL	7	affinity chromatography technology, imaging technique	Kumar B (2016), Kumar B (2016)	2
GRB2	2	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid	Sieg DJ (2000), Angers-Loustau A (1999), Hildebrand JD (1996), Messina S (2003), Arold ST (2002), Vinayagam A (2011)	6
CDC42	3	MAPK8	3	imaging technique	Chen TC (2014)	1
UHRF2	1	LYN	2	far western blotting	Mori T (2011)	1
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
LCK	0	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
TRIM25	5	YWHAE	0	affinity chromatography technology	Choudhury NR (2017)	1
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
ARHGAP32	11	CDC42	3	enzymatic study, enzymatic study, enzymatic study, two hybrid	Nakazawa T (2003), Zhao C (2003), Nakamura T (2002), Bandyopadhyay S (2010)	4
CRKL	1	DOCK1	14	affinity chromatography technology	Hein MY (2015)	1
BCAR1	6	NCK1	0	affinity chromatography technology, unspecified method	Okabe S (2002), Liu BA (2012)	2
FYN	1	TNK2	7	affinity chromatography technology, pull down	Linseman DA (2001), Linseman DA (2001)	2
GRB2	2	YWHAE	0	affinity chromatography technology	Bisson N (2011)	1
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
TNK2	7	CDC42	3	affinity chromatography technology, two hybrid, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, pull down, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down	Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Mott HR (1999), Mott HR (1999), Gu Y (2004), Gu Y (2004), Owen D (2000), Govind S (2001), Jones S (2014), Jones S (2014), Urena JM (2005), Urena JM (2005), Tetley GJN (2017), Tetley GJN (2017)	15
PTK2B	6	LYN	2	affinity chromatography technology	Yamasaki M (2001)	1
YWHAZ	1	BCAR1	6	two hybrid, pull down, affinity chromatography technology	Garcia-Guzman M (1999), Garcia-Guzman M (1999), Garcia-Guzman M (1999)	3
CBL	7	RAPGEF1	6	affinity chromatography technology, affinity chromatography technology	Uemura N (1999), Peterson ME (2008)	2
SRC	2	PXN	1	pull down	Angers-Loustau A (1999)	1
YWHAE	0	BCAR1	6	affinity chromatography technology	Gloeckner CJ (2007)	1
GRB2	2	PXN	1	pull down	Angers-Loustau A (1999)	1
CRK	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Larsson H (1999)	2
ABL1	9	SRC	2	pull down	Yu HH (2001)	1
PTEN	24	CRKL	1	affinity chromatography technology	Crockett DK (2005)	1
NEDD9	3	NCK1	0	affinity chromatography technology, pull down	Minegishi M (1996), Minegishi M (1996)	2
ID2	0	MAPK8	3	two hybrid	Wang J (2011)	1
HYOU1	2	ARMCX3	0	biochemical	Kristensen AR (2012)	1
SRC	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, imaging technique, imaging technique, imaging technique, pull down, imaging technique, imaging technique, affinity chromatography technology, two hybrid	Migliaccio A (2000), Teo AK (2001), Slentz-Kesler K (2000), Bourdoncle A (2005), Jaber BM (2004), Jaber BM (2004), Ku TK (2007), Cabodi S (2004), Monroe DG (2003), Hitosugi T (2007), Zwart W (2007), Zwart W (2007), Zwart W (2007), Yoshimaru T (2013), Yoshimaru T (2013), Zhang H (2006), Zhang H (2006), Zhang H (2006), Endler A (2012), Endler A (2012)	20
PTK2B	6	ERBB2	6	affinity chromatography technology, imaging technique	Zrihan-Licht S (2000), Chen TC (2014)	2
BCAR1	6	PTK2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Hsia DA (2003), Hildebrand JD (1996), Chellaiah MA (2001), Okabe S (2002), Wang JF (2000), Wu Y (2005), Ponnala S (2011), Cho SY (2002)	9
LYN	2	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Taher TE (2002), Dombrosky-Ferlan PM (1997), Kaabeche K (2004), Wu J (2008), Tanaka S (1995), Marcilla A (1995)	6
BCAR1	6	ABL1	9	affinity chromatography technology, enzymatic study	Salgia R (1996), Mayer BJ (1995)	2
BCAR1	6	ERBB2	6	affinity chromatography technology	Bisaro B (2016)	1
TNK2	7	HCK	5	pull down, pull down	Chan W (2011), Yokoyama N (2003)	2
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
HNRNPL	3	CD2AP	0	affinity chromatography technology	Fei T (2017)	1
LYN	2	PPP1R15A	2	two hybrid, affinity chromatography technology, pull down	Grishin AV (2001), Grishin AV (2001), Grishin AV (2001)	3
ARHGAP32	11	CRKL	1	pull down, affinity chromatography technology	Nakamura T (2002), Nakamura T (2002)	2
TNK2	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Satoh T (1996), Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Lin Q (2012), Yeow-Fong L (2005), Chan W (2011), Yokoyama N (2003), Huttlin EL (2017), Mahendrarajah N (2017)	10
TRIM25	5	GRB2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	BCAR1	6	affinity chromatography technology	Choudhury NR (2017)	1
VCL	6	HSPA5	0	biochemical	Kristensen AR (2012)	1
NPHP1	2	TNS1	6	affinity chromatography technology	Benzing T (2001)	1
TSG101	1	VPS11	3	two hybrid	Markson G (2009)	1
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
ALK	8	SRC	2	affinity chromatography technology	Ambrogio C (2005)	1
TRIM25	5	HSPA5	0	affinity chromatography technology	Choudhury NR (2017)	1
ITGAV	7	BCAR1	6	affinity chromatography technology	Elsegood CL (2006)	1
CBL	7	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vandenbroere I (2003), Prasad NK (2005), De Schutter J (2009), De Schutter J (2009), Brehme M (2009)	5
HCK	5	RAPGEF1	6	two hybrid, pull down, affinity chromatography technology	Shivakrupa R (2003), Shivakrupa R (2003), Shivakrupa R (2003)	3
GRB2	2	CD2AP	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Bisson N (2011), Wang J (2011)	3
ABL1	9	ERBB2	6	unspecified method	Jones RB (2006)	1
PTEN	24	ESR1	0	pull down	Lin HK (2004)	1
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
NEDD9	3	PTPN12	2	pull down	Cote JF (1998)	1
SRC	2	TNK2	7	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Chan W (2009), Modzelewska K (2006), Chan W (2011), Chan W (2011), Chan W (2011), Yokoyama N (2003)	6
ABL1	9	GRB2	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Warmuth M (1997), Ren R (1994), Ren R (1994), Patel H (2006), Johnson KJ (2009), Gaston I (2004), Gaston I (2004), Brehme M (2009), Brehme M (2009), Chen R (2013), Feller SM (1994)	11
TRIP6	2	VCL	6	two hybrid, two hybrid	Rual JF (2005), Yu H (2011)	2
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
NEDD9	3	LCK	0	affinity chromatography technology	Minegishi M (1996)	1
TSG101	1	SH3KBP1	1	biochemical	Wan C (2015)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
CRK	0	PTPN1	2	pull down	Liu F (1996)	1
TRIM25	5	BCAR3	5	affinity chromatography technology	Choudhury NR (2017)	1
YWHAZ	1	YWHAE	0	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, biochemical, affinity chromatography technology, pull down	Bandyopadhyay S (2010), Zippo A (2009), Zippo A (2009), Havugimana PC (2012), Gloeckner CJ (2007), Wang J (2011), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Gu YM (2006)	10
NCK1	0	ABL1	9	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Miyoshi-Akiyama T (2001), Ren R (1994), Ren R (1994), Wunderlich L (1999), Adler CE (2000)	5
BCAR1	6	PXN	1	affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Chellaiah MA (2001)	2
GRB2	2	ARHGAP32	11	two hybrid	Bandyopadhyay S (2010)	1
BCAR1	6	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Zhou B (2004), Di Stefano P (2004), Hsia DA (2003), Hsia DA (2003), Gu J (2001), Garton AJ (1999), Angers-Loustau A (1999), Qiu W (1998), Blaukat A (1999), Wang JF (2000), Holcomb M (2006), Wu Y (2005), Cho SY (2000), Modzelewska K (2006), Modzelewska K (2006), Brehme M (2009), Cho SY (2002), Cho SY (2002), Mielenz D (2001), Peterson ME (2008), Liu BA (2012), Larsson H (1999)	22
HNRNPL	3	DOCK1	14	affinity chromatography technology	Fei T (2017)	1
PTEN	24	PTK2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Tamura M (1999), Haier J (2002), Crockett DK (2005), Tamura M (1999), Tamura M (1999), Tamura M (1999)	6
GRB2	2	CDC42	3	two hybrid	Vinayagam A (2011)	1
PTPN12	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology	Charest A (1997), Charest A (1997), Bisson N (2011)	3
ESR1	0	ERBB2	6	affinity chromatography technology	Yang Z (2004)	1
ABL1	9	PIK3R1	6	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Kapeller R (1994), Ren SY (2005), Ren SY (2005), Ren SY (2005), Brehme M (2009)	5
MAPK8	3	SH2D3A	3	genetic interference	Lu Y (1999)	1
SRCIN1	3	CRK	0	affinity chromatography technology	Di Stefano P (2004)	1
BCAR1	6	KIF13A	3	biochemical	Kristensen AR (2012)	1
SH3KBP1	1	CD2AP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tossidou I (2010), Gaidos G (2007), Huttlin EL (2017)	3
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
FYN	1	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
ERBB2	6	SH2D3A	3	unspecified method	Jones RB (2006)	1
ID2	0	BCAR1	6	affinity chromatography technology	Law SF (1999)	1
TNK2	7	NCK1	0	pull down, affinity chromatography technology	Chan W (2011), Hein MY (2015)	2
HYOU1	2	KIF13A	3	biochemical	Kristensen AR (2012)	1
ESR1	0	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Cabodi S (2004), Robinson LJ (2009)	2
BCAR3	5	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Cai D (2003), Huttlin EL (2017)	2
CBL	7	MAPK8	3	affinity chromatography technology, enzymatic study	Miao H (2002), Miao H (2002)	2
BCAR1	6	PPP1R15A	2	two hybrid	Stelzl U (2005)	1
HSPA5	0	HNRNPL	3	biochemical	Havugimana PC (2012)	1
CBL	7	YWHAZ	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Robertson H (1997), Subramanian RR (2001), Wang H (1998)	3
BCAR1	6	ARMCX3	0	biochemical	Kristensen AR (2012)	1
GRB2	2	E2F2	0	two hybrid	Grossmann A (2015)	1
EFS	2	PTPN12	2	pull down	Cote JF (1998)	1
TRIM25	5	PTPN12	2	affinity chromatography technology	Choudhury NR (2017)	1
NPHP1	2	PTK2B	6	affinity chromatography technology, pull down	Benzing T (2001), Benzing T (2001)	2
NCK1	0	ARHGAP32	11	pull down, affinity chromatography technology	Zhao C (2003), Zhao C (2003)	2
HNRNPL	3	ERBB2	6	affinity chromatography technology	Fei T (2017)	1
PTEN	24	PTK2B	6	affinity chromatography technology	Crockett DK (2005)	1
BCAR1	6	PTEN	24	pull down	Tamura M (1999)	1
BCAR1	6	VCL	6	affinity chromatography technology	Chellaiah MA (2001)	1
HSPA5	0	NCK1	0	affinity chromatography technology	Misra UK (2005)	1
TNK2	7	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Modzelewska K (2006), Modzelewska K (2006)	2
ESR1	0	MDM2	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down	Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001)	8
CRKL	1	ABL1	9	affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heaney C (1997), Heaney C (1997), Heaney C (1997), Ren R (1994), Ren R (1994), Kyono WT (1998), Ren R (1994), Patel H (2006), Johnson KJ (2009), Ribon V (1996), Senechal K (1998), Nishihara T (2003), Peterson ME (2008)	13
PXN	1	LCK	0	affinity chromatography technology	Ostergaard HL (1998)	1
HSPA5	0	ID2	0	two hybrid, affinity chromatography technology	Wang J (2011), Lee SB (2016)	2
YWHAE	0	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	4
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
SFN	1	CBL	7	affinity chromatography technology	Subramanian RR (2001)	1
BCAR1	6	PTPN1	2	pull down, pull down, affinity chromatography technology, biochemical	Liu F (1996), Liu F (1996), Liu F (1996), Liu F (1996)	4
CRKL	1	RAPGEF1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kyono WT (1998), Grumbach IM (2001), Ahmad S (1997), Smit L (1996), Smit L (1996), Chin H (1997), Wu C (2001), Wu C (2001), Sakkab D (2000), Alsayed Y (2000), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Peterson ME (2008), Gutierrez-Berzal J (2006), Hein MY (2015)	16
BCAR1	6	SRCIN1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Di Stefano P (2004), Di Stefano P (2004), Di Stefano P (2004), Di Stefano P (2004)	4
BCAR1	6	HCK	5	pull down	Manie SN (1997)	1
ALK	8	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ambrogio C (2005), Ambrogio C (2005), Ambrogio C (2005)	3
GRB2	2	DOCK1	14	pull down, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hasegawa H (1996), Bandyopadhyay S (2010), Bisson N (2011), Huttlin EL (2017)	5
PTK2	2	CRK	0	affinity chromatography technology, pull down, two hybrid	Hsia DA (2003), Angers-Loustau A (1999), Grossmann A (2015)	3
CRK	0	PXN	1	pull down, affinity chromatography technology	Angers-Loustau A (1999), Abassi YA (2002)	2
TRIP6	2	PTK2	2	affinity chromatography technology	Xu J (2004)	1
ZYX	2	NEDD9	3	two hybrid	Yi J (2002)	1
LYN	2	SH2D3C	2	affinity chromatography technology	Zhu J (2013)	1
ARHGAP32	11	SRC	2	pull down, affinity chromatography technology	Moon SY (2003), Moon SY (2003)	2
CRK	0	HSPA5	0	affinity chromatography technology	Brehme M (2009)	1
BCAR1	6	CBL	7	affinity chromatography technology	Sawasdikosol S (1996)	1
HNRNPL	3	SRCIN1	3	affinity chromatography technology	Fei T (2017)	1
BCAR1	6	E2F2	0	two hybrid	Stelzl U (2005)	1
BCAR1	6	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Salgia R (1996), Salgia R (1996), Astier A (1997), Peterson ME (2008), Liu BA (2012)	5
ERBB2	6	BCAR3	5	unspecified method	Jones RB (2006)	1
BCAR1	6	GMPR2	1	biochemical	Kristensen AR (2012)	1
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
RAN	1	ABL1	9	affinity chromatography technology	Daniel R (2001)	1
MAPK14	0	BCAR1	6	affinity chromatography technology	Hein MY (2015)	1
YWHAE	0	VCL	6	biochemical	Kristensen AR (2012)	1
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
UHRF2	1	LCK	0	far western blotting	Mori T (2011)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
PIK3R1	6	EPN1	4	affinity chromatography technology	Bulut GB (2013)	1
BMX	0	PTK2	2	affinity chromatography technology, pull down	Chen R (2001), Chen R (2001)	2
YWHAZ	1	VCL	6	biochemical	Kristensen AR (2012)	1
HSPA5	0	HYOU1	2	affinity chromatography technology	Hein MY (2015)	1
INPPL1	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
PXN	1	VCL	6	pull down, pull down, pull down, biochemical	Turner CE (1999), Mazaki Y (1997), Brown MC (1996), Wan C (2015)	4
BCAR1	6	MMP14	0	affinity chromatography technology	Gingras D (2008)	1
HNRNPL	3	PTEN	24	affinity chromatography technology	Fei T (2017)	1
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
ABL1	9	RAPGEF1	6	affinity chromatography technology, pull down, enzymatic study	Gutierrez-Berzal J (2006), Gutierrez-Berzal J (2006), Gutierrez-Berzal J (2006)	3
TRIM25	5	INPPL1	6	affinity chromatography technology	Choudhury NR (2017)	1
ABL1	9	MDM2	2	affinity chromatography technology, pull down, enzymatic study, unspecified method, enzymatic study	Goldberg Z (2002), Goldberg Z (2002), Goldberg Z (2002), Batuello CN (2015), Batuello CN (2015)	5
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
CD2AP	0	CBL	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Haglund K (2004), Haglund K (2004), Kirsch KH (2001), Kirsch KH (2001), Cormont M (2003), Lynch DK (2003), Tibaldi EV (2003), Bao M (2012), Yao B (2007), Selbach M (2006), Taipale M (2014), Taipale M (2014), Igloi Z (2015)	13
BCAR1	6	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Nakamura T (2002)	3
YWHAZ	1	MDM2	2	affinity chromatography technology	Zhang B (2017)	1
TRIM25	5	LYN	2	affinity chromatography technology	Choudhury NR (2017)	1